Eight-month-old twins from Hayward Heath, West Sussex, recently met the surgeon who saved their lives even before they were born. The BBC reports how their mother, Katerina Ahouansou, at six months pregnant, during a routine scan, uncovered a serious issue with their development and blood supply.

Doctors diagnosed the twins with twin-to-twin transfusion syndrome or TTTS. It is a condition where one twin received more blood and nourishment than the other due to uneven blood vessel distribution in the placenta. In case there is no medical intervention, it could be fatal for both the twins.

A Specialist Steps In

This is when Ahouansou was referred to Professor Kypros Nicolaides at King’s College Hospital in London. Professor Nicolaides is a pioneer in fetal medicine and he specializes in a laser procedure that redistributes blood supply between twins in cases of TTTS.

When Ahouansou was scanned, Nicolaides observed that one of the twins were significantly smaller than the other. "There was a very high chance that if we did not intervene, both twins could die," he recalled.

An Operation No Less Than A Miracle

The life-saving laser surgery was performed and within a week the doctors saw an improvement with the twin who was smaller in size. When the twins were born, they weighed 1.5kg and 1.7kg. To recognize the efforts by the surgeon, Ahouansou named them Kai Kypros and Asher Nicolas after Professor Kypros Nicolaides.

Ahouansou also expressed deep gratitude for the professor's expertise and called him "proof that miracles can be performed by people who are devotees to their profession."

Professor Kypros Nicolaides has been at King’s College Hospital since 1980 and is widely regarded as a leader in fetal medicine. His groundbreaking research and development of screening and surgical techniques have saved countless lives.

Through his dedication, Professor Nicolaides has given many families hope, demonstrating how medical advancements continue to improve survival rates for complex fetal conditions like TTTS.

More about Twin-to-twin Transfusion Syndrome

As per the John Hopkins Medicine, TTTS is a rare pregnancy condition that affects identical twins or other multiples. It happens in pregnancies where twins share one placenta and a network of blood vessels that supply oxygen and nutrients essential for development in the womb. These pregnancies are known as monochorionic.

Sometimes, the blood vessels in the placenta are unevenly distributed, causing an imbalance in blood flow between the twins. The donor twin loses more blood than it receives, leading to malnutrition and potential organ failure. Meanwhile, the recipient twin gets an excess of blood, putting strain on the heart and increasing the risk of cardiac complications.

Impact on the Donor Twin

The donor twin loses blood volume (hypovolemia), reducing kidney function and urine production. This leads to low amniotic fluid levels (oligohydramnios) or, in severe cases, a complete absence (anhydramnios). Without proper blood circulation, the donor twin faces cardiovascular issues, increasing the risk of death.

Impact on the Recipient Twin

The recipient twin experiences excess blood volume (hypervolemia), causing increased urination and excessive amniotic fluid (polyhydramnios). The overworked heart struggles to handle the surplus blood, leading to cardiovascular dysfunction, heart failure, and, in extreme cases, death.

The pertussis vaccine, which protects against whooping cough (Bordetella pertussis), a highly contagious bacterial respiratory infection, offers strong protection in young children, according to a new study led by the US Centers for Disease Control and Prevention (CDC).

Published in the CDC’s Morbidity and Mortality Weekly Report (MMWR), the study found that children who received three or more doses of the diphtheria, tetanus, and acellular pertussis (DTaP) vaccine had 96.2% protection against laboratory-confirmed pertussis.

Pertussis Vaccine Offers Strong Protection

The DTaP vaccine is administered in a five-dose childhood series. The first dose is given at 2 months of age, followed by doses during infancy and early childhood. The final dose is recommended between ages 4 and 6 years.

The MMWR study compared children in Alaska who had received three or more DTaP doses with those who were unvaccinated or had received fewer doses than recommended.

Unvaccinated children had approximately 26 times the odds of developing laboratory-confirmed whooping cough compared with vaccinated children.

Overall, adjusted vaccine effectiveness against pertussis was 96.2% among children who had received three or more DTaP doses. Partial vaccination also offered protection, with effectiveness reaching 85.3% among children who had received one or two doses.

“Pertussis vaccination is effective in preventing laboratory-confirmed pertussis in young children,” said corresponding author Joseph McLaughlin of the Section of Epidemiology, Alaska Department of Health, Anchorage.

Also read: RSV Warning: Welsh Mum Urges Pregnant Women To Get Vaccine After Baby Nearly Dies

Whooping Cough Can Cause Severe Complications

Pertussis can cause serious complications in young children, including pneumonia, pauses in breathing (apnea), seizures, brain damage, and death. Severe coughing fits can also trigger vomiting and, in some cases, fractured ribs.

Infants younger than 6 months are particularly vulnerable because their immune systems are still developing. Babies may not develop the characteristic “whoop” sound and can instead experience feeding difficulties or pauses in breathing, making the infection harder to recognize.

According to a provisional CDC report, 16 people died from pertussis in the United States in 2025, including 10 infants.

Whooping cough spreads through respiratory droplets and can affect people of any age. However, newborns and people who are not adequately vaccinated face a greater risk of severe illness.

Previous research has also found that unvaccinated children are more likely to develop severe illness or require hospitalization than vaccinated children.

Childhood Vaccination Rates Have Declined In The US

Read More: US Kindergarten Vaccination Rates Decline, Exemptions Rise as Measles Cases Hit 35-Year High

Despite the protection offered by vaccination, DTaP coverage among US kindergartners has declined in recent years.

CDC data show that coverage fell to 92% in the 2025–26 school year, down from 95.2% in 2017–18.

The findings underscore the importance of maintaining high childhood vaccination coverage to reduce pertussis infections and protect children against severe illness and death.

Identifying Whooping Cough Symptoms

Whooping cough often begins with cold-like symptoms, including a runny nose, sneezing, a mild cough, and sometimes a low-grade fever. After one to two weeks, coughing fits may become more severe and persistent.

The cough can be followed by a characteristic whooping sound as the person gasps for air. Vomiting after coughing fits can also occur. However, symptoms vary, particularly in infants, who may experience breathing difficulties without a typical cough.

Diagnosis may involve laboratory testing of a nasal or throat sample. Early recognition is especially important in infants because the infection can progress to serious complications.

Herpes simplex virus (HSV), which commonly causes cold sores, usually causes mild symptoms in adults but can be life-threatening in newborns, whose immune systems are still developing.

Meg Edmonds, from Staffordshire, UK, lost her 10-day-old daughter, Magnolia, to HSV in February.

“We didn't know a cold sore could kill a baby,” Meg told the BBC. She is now urging parents to learn about the risks cold sores pose to newborns.

The virus is suspected to have been passed on to Magnolia by her mother.

“The guilt is obviously unbearable; it's horrific, but I just try and remind myself that I didn't know and I did what I could have done with the knowledge that I did have,” Meg said.

Mother Did Not Know Cold Sores Could Endanger Newborns

Also read: Rare Pregnancy Infections Linked To 3-Fold Higher Autism Risk: What Is TORCH?

The 22-year-old said Magnolia was born “perfectly healthy” after what she described as a straightforward “water birth”.

Only later did Meg realise she had a sore on her lip around the time of the birth.

“Looking back at photos now, I can see that I had a lesion or sore on my lip whilst I was giving birth which I thought nothing of at the time,” she said.

Meg, who had never experienced a cold sore before, sought advice from health professionals but was reassured that the sore was nothing to worry about.

“They just thought that I might need to drink more or that it might just have been hormonal from giving birth only the day prior, so I thought nothing of it,” she said.

Magnolia's condition later deteriorated, and she died from HSV, according to the report.

Cold Sore Outbreak Brings Back Painful Memories

Meg said she had avoided visitors who were unwell, never kissed Magnolia and washed her hands frequently to protect her newborn from infections.

“I washed my hands constantly because I was worried in general about infections. But I never knew that if that passed to her it could kill her,” she said.

A subsequent cold sore outbreak brought back painful memories.

“I'm constantly reminded anyway that my daughter isn't here any more and why that is, but to actually have a physical reminder on my face is horrible,” she said.

How To Protect Newborns From HSV

Read More: Baby Not Sitting by 9 Months? Warning Signs Parents Should Know

According to the UK's National Health Service (NHS), newborns are particularly vulnerable to HSV, especially during the first six weeks of life. The infection can affect the eyes, mouth and skin or spread to other organs, potentially becoming life-threatening.

HSV can spread after birth through contact with a cold sore, including when someone with an active cold sore kisses a baby. It can also spread through herpes blisters on the breast during breastfeeding.

The NHS recommends these precautions to reduce the risk of infection:

• Wash hands: Wash hands thoroughly before handling a newborn.
• Avoid kissing: People with an active cold sore should not kiss a baby.
• Prevent direct contact: Keep cold sores and other herpes lesions away from the baby.
• Take care during breastfeeding: Do not breastfeed from a breast with herpes blisters until they have healed. Seek medical advice about feeding and expressed milk from the affected breast.
• Inform healthcare professionals: Pregnant women with a history of genital herpes or symptoms of a possible infection should inform their doctor or midwife.

Warning Signs Of Neonatal Herpes

Babies may not develop visible blisters, and neonatal herpes can progress rapidly. Seek urgent medical attention if a newborn has:

• Unusual irritability or difficulty settling.
• Poor feeding or feeds less than usual.
• A fever of 38°C or higher.
• A rash or sores on the skin, eyes or inside the mouth.
• Unusual lethargy, floppiness or difficulty waking.
• Breathing difficulties or seizures.

Influenza and COVID-19 may trigger a rare but fatal brain condition in children, according to a new study published in Frontiers in Neurology.

Based on 138 reported cases of acute necrotizing encephalopathy (ANE), the research is built on 15 studies involving children under 18 diagnosed with ANE following respiratory viral infections.

ANE can cause rapid neurological deterioration, seizures and damage to deep structures of the brain, even in children who were previously healthy.

Influenza viruses accounted for 46% of the reported cases, while SARS-CoV-2, the COVID-19 virus, accounted for 42.3%. Together, they represented nearly 90% of the cases in the review.

The findings highlight the need to recognise neurological symptoms that develop after a child has a fever or respiratory infection.

However, ANE remains rare, and the study does not suggest that most children with flu or COVID-19 are at risk of developing the condition.

Flu And COVID-19 Accounted For Most Reported Cases

Influenza viruses were identified in 63 cases, while SARS-CoV-2 was identified in 58. Another 17 cases were linked to unspecified respiratory viral infections.

The findings suggest that influenza and COVID-19 are key reported triggers of ANE. However, the researchers cautioned that the studies were observations, and the findings cannot establish how often ANE develops among children infected with either virus.

Also read: Swimmer Archie Goodburn’s Plea Prompts UK Brain Cancer Research Review

What Is Acute Necrotizing Encephalopathy?

Acute necrotizing encephalopathy is a rare neurological disorder in which inflammation and tissue injury cause damage to the brain. It is mostly linked with a respiratory viral infection.

The condition is characterised by lesions in the thalami, two structures deep inside the brain that help process sensory information and regulate functions like alertness.

In some children, damage also affects the brainstem and other regions. Rather than the virus directly destroying brain tissue, an excessive inflammatory response may disrupt the blood-brain barrier, allowing inflammation to damage the brain.

Symptoms of Acute Necrotizing Encephalopathy

ANE usually starts with symptoms of the initial viral infection, like fever, cough, vomiting, and diarrhea, followed by rapid neurological decline, which may include:

• Seizures
• Confusion, drowsiness, and altered consciousness
• Coma lasting for weeks
• Problems with movement (ataxia)
• Abnormal muscle tone

One of the most concerning features of ANE is how quickly a child's condition can worsen after a febrile illness.

In the reviewed cases, fever was reported in 93.4% of children, altered consciousness in 94.9% and seizures in 68.6%. These figures describe children who had ANE, not all children with respiratory infections.

These symptoms require emergency medical assessment. Parents should not wait for a fever or other infection symptoms to resolve if a child develops seizures, confusion or reduced consciousness.

Mortality Rate Of ANE

Despite treatment, the outcomes reported in the study were serious. Of the 138 children included in the review, 54 died, giving a reported mortality proportion of 39.1%.

Survivors also experienced neurological complications, including problems affecting movement, cognition and development.

It is important to note that the study included published cases of a rare and severe disease, which may overrepresent children with particularly serious illness. It is not a population-wide estimate of the risk of death from ANE. Brain imaging like MRI can help doctors identify the characteristic lesions associated with the condition.