Eight-month-old twins from Hayward Heath, West Sussex, recently met the surgeon who saved their lives even before they were born. The BBC reports how their mother, Katerina Ahouansou, at six months pregnant, during a routine scan, uncovered a serious issue with their development and blood supply.

Doctors diagnosed the twins with twin-to-twin transfusion syndrome or TTTS. It is a condition where one twin received more blood and nourishment than the other due to uneven blood vessel distribution in the placenta. In case there is no medical intervention, it could be fatal for both the twins.

A Specialist Steps In

This is when Ahouansou was referred to Professor Kypros Nicolaides at King’s College Hospital in London. Professor Nicolaides is a pioneer in fetal medicine and he specializes in a laser procedure that redistributes blood supply between twins in cases of TTTS.

When Ahouansou was scanned, Nicolaides observed that one of the twins were significantly smaller than the other. "There was a very high chance that if we did not intervene, both twins could die," he recalled.

An Operation No Less Than A Miracle

The life-saving laser surgery was performed and within a week the doctors saw an improvement with the twin who was smaller in size. When the twins were born, they weighed 1.5kg and 1.7kg. To recognize the efforts by the surgeon, Ahouansou named them Kai Kypros and Asher Nicolas after Professor Kypros Nicolaides.

Ahouansou also expressed deep gratitude for the professor's expertise and called him "proof that miracles can be performed by people who are devotees to their profession."

Professor Kypros Nicolaides has been at King’s College Hospital since 1980 and is widely regarded as a leader in fetal medicine. His groundbreaking research and development of screening and surgical techniques have saved countless lives.

Through his dedication, Professor Nicolaides has given many families hope, demonstrating how medical advancements continue to improve survival rates for complex fetal conditions like TTTS.

More about Twin-to-twin Transfusion Syndrome

As per the John Hopkins Medicine, TTTS is a rare pregnancy condition that affects identical twins or other multiples. It happens in pregnancies where twins share one placenta and a network of blood vessels that supply oxygen and nutrients essential for development in the womb. These pregnancies are known as monochorionic.

Sometimes, the blood vessels in the placenta are unevenly distributed, causing an imbalance in blood flow between the twins. The donor twin loses more blood than it receives, leading to malnutrition and potential organ failure. Meanwhile, the recipient twin gets an excess of blood, putting strain on the heart and increasing the risk of cardiac complications.

Impact on the Donor Twin

The donor twin loses blood volume (hypovolemia), reducing kidney function and urine production. This leads to low amniotic fluid levels (oligohydramnios) or, in severe cases, a complete absence (anhydramnios). Without proper blood circulation, the donor twin faces cardiovascular issues, increasing the risk of death.

Impact on the Recipient Twin

The recipient twin experiences excess blood volume (hypervolemia), causing increased urination and excessive amniotic fluid (polyhydramnios). The overworked heart struggles to handle the surplus blood, leading to cardiovascular dysfunction, heart failure, and, in extreme cases, death.

Pregnancy is probably one of the most important periods in a woman’s life during which her decisions regarding nutrition, exercise, and many other factors can directly affect the health of the fetus.

Today, doctors are paying more attention to the impact that modern lifestyle trends have on pregnant women and their babies, since improper nutrition, sedentary lifestyle, too much use of electronic devices, stress, and bad sleeping habits are causing various problems during pregnancy.

The Role Of Nutrition And Exercise In Pregnancy

A good diet that provides all the necessary nutrition is another vital factor in pregnancy. The development of the baby relies completely on the nutrients provided by the mother in terms of iron, calcium, folic acid, protein, and vitamins.

Inadequate nutrition can cause various issues such as poor body weight, anemia, delays in the process of development, and premature delivery. Excessive intake of processed food, sugar-filled drinks, and junk food can cause the development of gestational diabetes, obesity, and high blood pressure in the course of pregnancy.

Exercise is also essential when it comes to sustaining a healthy pregnancy. Exercises such as walking, prenatal yoga, and stretching will aid women in improving their blood flow, managing their weight, reducing stress, and minimizing the chances of developing complications due to pregnancy.

However, it should be noted that pregnant women should not engage in rigorous exercise.

Why Managing Stress Is Key

Stress and mental health hold equal importance for pregnant women. Stressful situations may have a negative effect on the mother as well as the unborn child. Emotional stress, insomnia, anxiety, and occupational stress may result in hypertension, premature childbirth, and low birth weight.

Research indicates that prolonged maternal stress may even affect the neurodevelopment and behavior of the fetus. Thus, it becomes important to ensure the emotional stability of the pregnant woman through relaxation exercises and sufficient sleep.

The Importance of Sleep And Healthy Lifestyle Practices

Sleep is also an important yet underrated aspect that needs to be considered. Disrupted sleeping habits, working late into the night, and a lack of proper sleep may have adverse impacts on the hormonal balance of the body, thereby causing fatigue. Good sleep is essential for the body’s healing process, proper regulation of blood pressure, and the development of the fetus.

Some of the lifestyle practices may pose serious risks to the development of the fetus. The use of cigarettes, drinking alcoholic beverages, and drug abuse while being pregnant is linked to congenital anomalies, poor fetal growth, prematurity, and developmental problems. It should also be noted that secondhand smoke poses health risks to the baby.

A Healthy Pregnancy

Prenatal examinations are crucial in maintaining the well-being of the mother and fetus during the period of gestation. Early detection of possible problems through ultrasound, blood tests, immunization, and physician consultations can be achieved through regular prenatal examinations.

A healthy pregnancy does not merely involve avoiding diseases; it involves establishing an optimal environment for fetal growth and development. Healthy behaviors during pregnancy not only benefit the mother but also provide an excellent starting point for the health of her child in the future. With modern changes in lifestyle patterns, it is now more essential than ever before to be aware of and prevent any problems that might arise during pregnancy.

Dengue affects children differently from adults, making them among the most vulnerable groups to the mosquito-borne disease. While platelet monitoring remains important, experts on National Dengue Day 2026 stressed that dengue severity depends on a child’s overall clinical condition and not just a single laboratory value.

Speaking to HealthandMe, the doctors informed that there is more than a falling platelet count among children and shared warning signs that parents must never ignore.

Dr. Vijay Yewale, Head Pediatrician at Apollo Hospitals, Mumbai, said many parents panic when platelet counts begin to fall during dengue infection. However, he stressed that serious complications such as bleeding can occur even when platelet levels are not critically low.

“It is important to remember that while platelet count needs to be watched closely during dengue, serious complications such as bleeding, fluid leakage, or organ involvement can sometimes occur even when platelet levels are not very low,” Dr. Vijay said.

He explained that many children with low platelet counts recover completely with proper monitoring and supportive care.

According to Dr. Yewale, the most critical stage of dengue usually begins when the fever starts coming down and may last for 24 to 48 hours. During this phase, some children can rapidly progress to severe dengue due to plasma leakage.

“This can quickly become life-threatening, as fluid leaking from damaged blood vessels may lead to a drop in blood pressure and shock, impaired blood supply to vital organs, and failure of multiple organs. If not recognized and treated promptly, severe dengue can even result in death,” he added.

How Dengue Symptoms In Infants Are Different

Dr. Rahul Nagpal, Principal Director and Head of Pediatrics & Neonatology at Fortis Vasant Kunj, highlighted that dengue symptoms in infants and toddlers are often very different from those seen in older children and adults, making diagnosis more challenging.

“In infants and toddlers, dengue symptoms are often subtle and nonspecific. Unlike adults who commonly complain of severe headaches, muscle pain, or joint pain, young children may simply become irritable, unusually sleepy, less active, or unwilling to feed. In many cases, fever may be the only noticeable symptom during the early stage of infection,” Dr. Rahul told HealthandMe.

The doctors warned that infants and young children are particularly vulnerable to dehydration because of smaller fluid reserves. Their condition can quickly worsen due to:

• Fever,
• vomiting,
• poor feeding,
• fluid loss.

• dry lips,
• reduced urination,
• sunken eyes,
• absence of tears while crying,
• unusual lethargy.

Warning Signs Parents Should Not Ignore

The doctors advised parents to monitor warning signs beyond platelet numbers, which need immediate medical attention. This includes:

• persistent vomiting,
• severe stomach pain,
• bleeding from the gums or nose,
• unusual drowsiness,
• restlessness,
• breathing difficulty,
• dizziness,
• Reduced urine output
• abdominal swelling or pain,
• cold hands and feet,
• seizures.

Why Diagnosing Dengue In Children Is Still A Challenge

The experts noted that diagnosing dengue in infants can be difficult because its symptoms often resemble common viral infections. Additionally, young children cannot clearly express discomfort, making close observation by parents and healthcare providers extremely important during the dengue season.

There is also no specific antiviral treatment for dengue currently available for children. Management mainly includes adequate fluid intake, breastfeeding or frequent feeding for infants, rest, fever management using paracetamol, and careful medical monitoring. Aspirin and ibuprofen are generally avoided because they may increase the risk of bleeding.

Prevention Remains The Best Protection

Doctors reiterated that mosquito bite prevention remains the best protection against dengue, especially for infants and young children. The use of mosquito nets, protective clothing, and the elimination of stagnant water around homes were strongly recommended.

The experts added that with early diagnosis, proper hydration, and timely medical care, most children with dengue recover fully.

A large new study, published in the Lancet Psychiatry journal, has shown that using antidepressant medications during pregnancy does not increase the risk of developmental disorders such as autism and attention-deficit/hyperactivity disorder (ADHD) in children.

The analysis, based on data from more than 25 million pregnancies, refutes assertions made by Robert F. Kennedy Jr. and states that there is no evidence to support a causal link between the use of almost all antidepressants during pregnancy and an increased risk of neurodevelopmental disorders.

Kennedy has previously claimed, without evidence, that certain antidepressants pose such a risk to fetuses. He has also linked vaccines to autism — a theory that has been widely debunked and contradicts established scientific evidence. The exact causes of autism remain unclear, though scientists believe neurological characteristics may begin developing in utero as the fetal brain forms.

“We know many parents-to-be worry about the potential impact of taking medication during pregnancy; our study provides reassuring evidence that commonly used antidepressants do not increase the risk of neurodevelopmental disorders such as autism and ADHD in children,” said Dr. Wing-Chung Chang of the University of Hong Kong.

Dr. Chang also warned against stopping antidepressant medication during pregnancy without medical advice.

“While all medications carry risks, so too does stopping antidepressants during pregnancy due to an increased risk of relapse,” he said.

He added that for women with moderate-to-severe depression, doctors and patients must carefully weigh the potential risks and benefits of continuing antidepressant treatment during pregnancy against the potential harms of untreated depression.

What Did The Study Find?

The meta-analysis was based on pooled data from 37 studies involving more than 600,000 pregnant women taking antidepressants and nearly 25 million pregnancies without antidepressant use.

Before adjusting for key factors such as underlying mental health conditions, the analysis found that antidepressant use during pregnancy was associated with:

• A 35 per cent increased risk of ADHD
• A 69 per cent increased risk of autism

However, these associations became greatly reduced or statistically non-significant after accounting for confounding factors.

Interestingly, antidepressant use by fathers during pregnancy was also associated with:

• A 46 per cent increase in ADHD risk
• A 28 per cent increase in autism risk

“Although our study found a small increase in the risk of autism and ADHD in the children of women who had used antidepressants during pregnancy, it also found that this risk disappeared when we accounted for other factors,” Dr. Chang said.

“The increased risk was also seen in the children of fathers who took antidepressants and of mothers with antidepressant use before, but not during, pregnancy,” he added.

“Together, this suggests that it is not the antidepressants themselves causing an increased risk of autism and ADHD, but it is more likely due to other factors, including genetic predisposition to conditions such as ADHD, autism, and mental health conditions,” the researcher explained.

Which Drugs Were Linked To Increased Risk?

Among the studies analysed, researchers found that only amitriptyline and nortriptyline remained associated with increased ADHD and autism risk.

These medications are generally considered second- or third-line treatment options for depression and are often prescribed in cases of treatment-resistant depression.

Researchers noted that women taking these medications may have more severe, chronic, or complex underlying mental health conditions, which could influence the observed association.

The study also found no difference in risk between high and low doses of antidepressants.

“The evidence suggests a link between either parent having a mental health condition and a slightly higher risk of ADHD or autism,” said Dr. Joe Kwun-Nam Chan of the University of Hong Kong.

“In addition to genetic factors, this link could be explained by the home and social environment, as ongoing family stress, changes in family functioning, and differences in parenting and caregiving may influence neurodevelopment,” he added.

He stressed the importance of ensuring that both parents have access to mental health support and treatment, both for their own wellbeing and to support the neurodevelopment of their child.

Limitations Of The Study

The researchers acknowledged several limitations, including a lack of data on factors such as socioeconomic status, lifestyle-related risks, and low birth weight in some studies.

Additionally, only a small number of studies examined antidepressant use during specific trimesters or evaluated exact dosage changes, making it difficult to draw firm conclusions in these areas.

The authors also noted that women prescribed antidepressants often have more severe depression than those who are not prescribed medication, meaning some bias may still remain despite adjustments for mental health conditions.