Eight-month-old twins from Hayward Heath, West Sussex, recently met the surgeon who saved their lives even before they were born. The BBC reports how their mother, Katerina Ahouansou, at six months pregnant, during a routine scan, uncovered a serious issue with their development and blood supply.

Doctors diagnosed the twins with twin-to-twin transfusion syndrome or TTTS. It is a condition where one twin received more blood and nourishment than the other due to uneven blood vessel distribution in the placenta. In case there is no medical intervention, it could be fatal for both the twins.

A Specialist Steps In

This is when Ahouansou was referred to Professor Kypros Nicolaides at King’s College Hospital in London. Professor Nicolaides is a pioneer in fetal medicine and he specializes in a laser procedure that redistributes blood supply between twins in cases of TTTS.

When Ahouansou was scanned, Nicolaides observed that one of the twins were significantly smaller than the other. "There was a very high chance that if we did not intervene, both twins could die," he recalled.

An Operation No Less Than A Miracle

The life-saving laser surgery was performed and within a week the doctors saw an improvement with the twin who was smaller in size. When the twins were born, they weighed 1.5kg and 1.7kg. To recognize the efforts by the surgeon, Ahouansou named them Kai Kypros and Asher Nicolas after Professor Kypros Nicolaides.

Ahouansou also expressed deep gratitude for the professor's expertise and called him "proof that miracles can be performed by people who are devotees to their profession."

Professor Kypros Nicolaides has been at King’s College Hospital since 1980 and is widely regarded as a leader in fetal medicine. His groundbreaking research and development of screening and surgical techniques have saved countless lives.

Through his dedication, Professor Nicolaides has given many families hope, demonstrating how medical advancements continue to improve survival rates for complex fetal conditions like TTTS.

More about Twin-to-twin Transfusion Syndrome

As per the John Hopkins Medicine, TTTS is a rare pregnancy condition that affects identical twins or other multiples. It happens in pregnancies where twins share one placenta and a network of blood vessels that supply oxygen and nutrients essential for development in the womb. These pregnancies are known as monochorionic.

Sometimes, the blood vessels in the placenta are unevenly distributed, causing an imbalance in blood flow between the twins. The donor twin loses more blood than it receives, leading to malnutrition and potential organ failure. Meanwhile, the recipient twin gets an excess of blood, putting strain on the heart and increasing the risk of cardiac complications.

Impact on the Donor Twin

The donor twin loses blood volume (hypovolemia), reducing kidney function and urine production. This leads to low amniotic fluid levels (oligohydramnios) or, in severe cases, a complete absence (anhydramnios). Without proper blood circulation, the donor twin faces cardiovascular issues, increasing the risk of death.

Impact on the Recipient Twin

The recipient twin experiences excess blood volume (hypervolemia), causing increased urination and excessive amniotic fluid (polyhydramnios). The overworked heart struggles to handle the surplus blood, leading to cardiovascular dysfunction, heart failure, and, in extreme cases, death.

Herpes simplex virus (HSV), which commonly causes cold sores, usually causes mild symptoms in adults but can be life-threatening in newborns, whose immune systems are still developing.

Meg Edmonds, from Staffordshire, UK, lost her 10-day-old daughter, Magnolia, to HSV in February.

“We didn't know a cold sore could kill a baby,” Meg told the BBC. She is now urging parents to learn about the risks cold sores pose to newborns.

The virus is suspected to have been passed on to Magnolia by her mother.

“The guilt is obviously unbearable; it's horrific, but I just try and remind myself that I didn't know and I did what I could have done with the knowledge that I did have,” Meg said.

Mother Did Not Know Cold Sores Could Endanger Newborns

Also read: Rare Pregnancy Infections Linked To 3-Fold Higher Autism Risk: What Is TORCH?

The 22-year-old said Magnolia was born “perfectly healthy” after what she described as a straightforward “water birth”.

Only later did Meg realise she had a sore on her lip around the time of the birth.

“Looking back at photos now, I can see that I had a lesion or sore on my lip whilst I was giving birth which I thought nothing of at the time,” she said.

Meg, who had never experienced a cold sore before, sought advice from health professionals but was reassured that the sore was nothing to worry about.

“They just thought that I might need to drink more or that it might just have been hormonal from giving birth only the day prior, so I thought nothing of it,” she said.

Magnolia's condition later deteriorated, and she died from HSV, according to the report.

Cold Sore Outbreak Brings Back Painful Memories

Meg said she had avoided visitors who were unwell, never kissed Magnolia and washed her hands frequently to protect her newborn from infections.

“I washed my hands constantly because I was worried in general about infections. But I never knew that if that passed to her it could kill her,” she said.

A subsequent cold sore outbreak brought back painful memories.

“I'm constantly reminded anyway that my daughter isn't here any more and why that is, but to actually have a physical reminder on my face is horrible,” she said.

How To Protect Newborns From HSV

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According to the UK's National Health Service (NHS), newborns are particularly vulnerable to HSV, especially during the first six weeks of life. The infection can affect the eyes, mouth and skin or spread to other organs, potentially becoming life-threatening.

HSV can spread after birth through contact with a cold sore, including when someone with an active cold sore kisses a baby. It can also spread through herpes blisters on the breast during breastfeeding.

The NHS recommends these precautions to reduce the risk of infection:

• Wash hands: Wash hands thoroughly before handling a newborn.
• Avoid kissing: People with an active cold sore should not kiss a baby.
• Prevent direct contact: Keep cold sores and other herpes lesions away from the baby.
• Take care during breastfeeding: Do not breastfeed from a breast with herpes blisters until they have healed. Seek medical advice about feeding and expressed milk from the affected breast.
• Inform healthcare professionals: Pregnant women with a history of genital herpes or symptoms of a possible infection should inform their doctor or midwife.

Warning Signs Of Neonatal Herpes

Babies may not develop visible blisters, and neonatal herpes can progress rapidly. Seek urgent medical attention if a newborn has:

• Unusual irritability or difficulty settling.
• Poor feeding or feeds less than usual.
• A fever of 38°C or higher.
• A rash or sores on the skin, eyes or inside the mouth.
• Unusual lethargy, floppiness or difficulty waking.
• Breathing difficulties or seizures.

Influenza and COVID-19 may trigger a rare but fatal brain condition in children, according to a new study published in Frontiers in Neurology.

Based on 138 reported cases of acute necrotizing encephalopathy (ANE), the research is built on 15 studies involving children under 18 diagnosed with ANE following respiratory viral infections.

ANE can cause rapid neurological deterioration, seizures and damage to deep structures of the brain, even in children who were previously healthy.

Influenza viruses accounted for 46% of the reported cases, while SARS-CoV-2, the COVID-19 virus, accounted for 42.3%. Together, they represented nearly 90% of the cases in the review.

The findings highlight the need to recognise neurological symptoms that develop after a child has a fever or respiratory infection.

However, ANE remains rare, and the study does not suggest that most children with flu or COVID-19 are at risk of developing the condition.

Flu And COVID-19 Accounted For Most Reported Cases

Influenza viruses were identified in 63 cases, while SARS-CoV-2 was identified in 58. Another 17 cases were linked to unspecified respiratory viral infections.

The findings suggest that influenza and COVID-19 are key reported triggers of ANE. However, the researchers cautioned that the studies were observations, and the findings cannot establish how often ANE develops among children infected with either virus.

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What Is Acute Necrotizing Encephalopathy?

Acute necrotizing encephalopathy is a rare neurological disorder in which inflammation and tissue injury cause damage to the brain. It is mostly linked with a respiratory viral infection.

The condition is characterised by lesions in the thalami, two structures deep inside the brain that help process sensory information and regulate functions like alertness.

In some children, damage also affects the brainstem and other regions. Rather than the virus directly destroying brain tissue, an excessive inflammatory response may disrupt the blood-brain barrier, allowing inflammation to damage the brain.

Symptoms of Acute Necrotizing Encephalopathy

ANE usually starts with symptoms of the initial viral infection, like fever, cough, vomiting, and diarrhea, followed by rapid neurological decline, which may include:

• Seizures
• Confusion, drowsiness, and altered consciousness
• Coma lasting for weeks
• Problems with movement (ataxia)
• Abnormal muscle tone

One of the most concerning features of ANE is how quickly a child's condition can worsen after a febrile illness.

In the reviewed cases, fever was reported in 93.4% of children, altered consciousness in 94.9% and seizures in 68.6%. These figures describe children who had ANE, not all children with respiratory infections.

These symptoms require emergency medical assessment. Parents should not wait for a fever or other infection symptoms to resolve if a child develops seizures, confusion or reduced consciousness.

Mortality Rate Of ANE

Despite treatment, the outcomes reported in the study were serious. Of the 138 children included in the review, 54 died, giving a reported mortality proportion of 39.1%.

Survivors also experienced neurological complications, including problems affecting movement, cognition and development.

It is important to note that the study included published cases of a rare and severe disease, which may overrepresent children with particularly serious illness. It is not a population-wide estimate of the risk of death from ANE. Brain imaging like MRI can help doctors identify the characteristic lesions associated with the condition.

India's food safety regulator has proposed implementing a restriction on adding sucrose and fructose to foods for babies up to six months old. The move aims to reduce consumption of added sugars during early infancy, which is considered to be a crucial period for growth and development.

The Food Safety and Standards Authority of India (FSSAI) has published a draft amendment to the Food Safety and Standards (Foods for Infant Nutrition) Regulations, 2020. The proposal was published in the Gazette of India on October 16, 2026, and announced by the Ministry of Health and Family Welfare on October 17.

Under the proposed amendment, “sucrose and fructose shall not be added in the products intended for infants up to the age of 6 months”. The FSSAI has kept the proposal open, inviting objections and suggestions within 60 days of the Gazette copies being made available.

FSSAI's Proposal For Baby Foods

Sucrose is the most common sugar found in many baby foods, while fructose is a naturally occurring sugar found in fruits and some other foods. Both can also be used as ingredients in certain manufactured foods products.

Under the existing infant nutrition regulations, lactose and glucose polymers are the preferred carbohydrate sources. Sucrose and fructose can be added when carbohydrate sources need to be added, subject to prescribed limits.

The proposed amendment would restrict that allowance for baby foods for infants up to six months. The proposal concerns the addition of these sugars to regulated infant nutrition products.

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Is Added Sugar A Concern In Early Infancy?

The first six months of life are important for an infant's physical growth and development. During this period, babies need nutrition that meets the requirements needed for growth, rather than ingredients added simply to increase sweetness.

FSSAI says the proposed restriction aims to ensure that infant nutrition products meet these needs without unnecessary additions of sucrose and fructose. The move is also part of a measure towards wider public health efforts to curb dietary risk factors like childhood obesity and other metabolic health problems.

The proposal, therefore, focuses on reducing unnecessary added sugars and strengthening nutritional standards for this age group.

Also read: Childhood Fitness Linked To Lower Risk Of Depression In Adulthood: 30-Year Study

Could This Improve Infant Health?

If the amendment is finalised, manufacturers will need to formulate baby food products for babies up to six months in accordance with the new restriction. The benefits of this move include:

• Reducing unnecessary added sugars: Infant nutrition products would no longer be permitted to contain added sucrose or fructose for this age group under the proposed rule.
• Supporting age-appropriate nutrition: Manufacturers would need to ensure their formulations meet infants' nutritional requirements without relying on these sugars.
• Strengthening preventive nutrition: The proposal forms part of wider efforts to promote healthier feeding practices from the earliest stages of life.

The actual health impact will depend on how the rules are implemented and the nutritional composition of the products affected.

The proposed restriction also supports established public health recommendations that promote exclusive breastfeeding during the first six months of life.

For parents who cannot breastfeed or need an alternative for medical or other reasons, an appropriate infant formula can help meet a baby's nutritional needs. Parents should consult a qualified healthcare professional about feeding choices rather than preparing homemade substitutes.