Lots of health videos circulate on social media, but one of the topic that grabbed attention of many is how man's sperm can affect not just the child's genes, but a mother's pregnancy experience. Dr Kirtly Jones, who has also been featured in the podcast of Health, University of Utah gives insight to how men influence pregnancy and what can to do to prepare for a healthy pregnancy of their partners.

Over the last two decades, researchers have discovered some fascinating insights on how genes can be influenced very early in the development. It could be as early as after fertilization. This is even before the woman herself realizes that she is pregnancy. This is a crucial time for the embryo and it can switch genes on or off to alter the way they function. This is also known as epigenetics. This does not change the DNA, however, it does modify how genes are expressed, and determines how they produce proteins and lastly, how it functions. These changes could continue throughout pregnancy and well into early childhood.

Role of the sperm

Historically and conventionally, the role of men in reproduction was believed to be limited to providing genetic material through sperm. This was thought as a simple delivery of DNA to the egg. However, there have been research that prove that this is more complex than thought.

Turns out, that genes in sperm can also be influenced by the environment in which they develop inside the man. These environmental modifications to sperm could also carry over and affect the development of the child.

In a 2013 study, published in the Journal of Neuroscience, it was studied how stress in male mice impacts their offspring. The researchers were able to see that stressed mouse dads experienced changes in their sperm and their offspring also exhibited abnormal stress. This was different when the offspring were compared to those of non-stressed dads.

For a mouse, it takes around 42 days to produce sperm and it was during this period when the mouse dads were exposed to stressors. This involved smell of foxes, wet bedding, brief restriction in a tube, and unfamiliar noises. Although DNA of the stressed dads' sperm was identical to that of the non-stressed mouse dad, the way it was processed was totally different.

These changes in sperm epigenetics is what led to stress responses abnormalities in the offspring as adults.

Now, talking about the human dads, or dads-to-be, precisely, the evidence that a father's health and behavior can also affect their sperm could be seen. A study that examined the cord blood of babies born to obese men revealed changes in how a particular gene regulating growth and calorie was expressed.

Wait, there's more!

What men eat could also impact how a mother feels during pregnancy.

While women are asked to not drink and smoke during pregnancy because it may impact the baby's health, it is also because babies are literally connected to mothers. But does dad's behavior matter too?

A fetus is physically connected to its mother, and factors like her physical and mental health, exposure to toxins, and nutrition have long been acknowledged as key to a newborn’s fitness. Yet the father’s role in ensuring a healthy pregnancy is often overlooked. That’s unfortunate because growing evidence suggests that fathers play a much more significant role than previously thought.

What’s more, this responsibility doesn’t just begin at conception. Both parents’ health and lifestyle choices before trying to conceive can profoundly influence their baby’s health.

How does it influence pregnancy and child's health?

Sperm plays a vital role in the formation of the placenta, a structure crucial to fetal development. Impaired sperm has been linked to higher miscarriage rates, likely because damaged sperm contains elevated levels of harmful free radicals.

There have been studies that proved that sperm can carry "biological memories" of environmental and lifestyle factors that influence gene expression. These epigenetic changes don’t alter the DNA itself but affect how genes function, leaving chemical marks on them. Alarmingly, these modifications can be passed down to future generations.

In rodent studies, exposure to certain endocrine disruptors caused epigenetic changes in sperm that were transmitted to over 90% of male descendants for up to three generations. This process, known as transgenerational epigenetic inheritance, highlights how a father’s environment and habits can have far-reaching consequences.

Children are sponges, picking up the behaviors and feelings of those around them, particularly their mothers. For one mother, the moment of realization came when she saw that her daughter was observing and learning everything—how she approached relationships, how she dealt with emotions, and how she established love and self-worth. That moment defined every choice she made, reaffirming a fact backed up by research: a mother's happiness is the number one predictor of a child's success.

Maternal satisfaction, usually quantified as subjective well-being, includes emotional well-being, satisfaction with life, and fulfillment. Maternal satisfaction is a function of numerous factors such as financial stability, social support systems, mental well-being, and work-life balance. Research, for instance, conducted at Ohio State University, verifies that children born to happier mothers are more likely to perform well academically, have better cognitive skills, and have fewer behavioral issues.

Cognitive and Emotional Development

Kids brought up in a home with a contented mother are likely to have better problem-solving abilities, greater emotional intelligence, and a positive learning attitude. When a mother takes care of herself, she creates a situation where her child feels safe, cared for, and motivated to excel.

Moreover, maternal happiness influences emotional stability. Children reflect their parents’ emotional states, meaning a mother who manages stress and prioritizes joy instills emotional resilience in her child. The result? A child who approaches challenges with confidence and composure.

The Behavioral Connection

A mother's joy is also a primary factor in determining the behavior of a child. The more joyful the mother, the more patient, caring, and involved she is, resulting in a warm and not tense home. This stability greatly minimizes the risk of anxiety, hostility, and other behavioral issues among children.

Successful parenting techniques also derive from maternal happiness. Mothers who are happy and emotionally stable tend to be more consistent in their discipline, provide praise, and communicate openly—ingredients for the confident and well-adjusted child.

How to Support Mothers for Brighter Futures and Kids?

Understandably recognizing the pivotal position of happiness in mothers, it becomes a priority to ensure mothers get the support they require. The most important factors that promote a mother's well-being are:

Mental Health Resources: Access to counseling, therapy, and stress management initiatives.

Work-Life Balance: Family-friendly policies that allow flexible work hours and parental leave.

Social Support: Family networks, family support, and peer support groups.

Financial Stability: Financial security that alleviates stress and enables mothers to provide more for their children.

The mother who had worried about bringing up her daughter in a "broken home" discovered that a broken relationship is not a broken life. Rather, by putting herself first and taking care of herself, she gave her daughter the greatest gift: a model of self-worth, resilience, and emotional health.

A happy mother isn't solely about her—it's the key to a child's success. When mothers are successful, their children thrive, showing that a happy mother indeed builds a successful future.

Pregnancy is usually a period of euphoria and expectation, but what if the symptoms of loose stools, stomach pain, and dizziness are warning signs of something far more dangerous? Although morning sickness and fatigue are usual, these symptoms could be the sign of an ectopic pregnancy—a life-threatening condition affecting about 2% of all pregnancies. Interestingly enough, more than 90% of ectopic pregnancies are located in the fallopian tubes, where the implanted fertilized egg is found outside the uterus and can rupture, causing profuse internal bleeding. If this isn't treated, it will result in death. So how do you know when you are in danger, and what should you do if you are?

Although some aches and pains are usual, some symptoms warrant immediate medical intervention. Have you had loose stools and abdominal discomfort in early pregnancy? They may be more than just stomach upsets—they may be indicative of an ectopic pregnancy, which is a dangerous condition needing to be treated promptly.

What is Ectopic Pregnancy?

An ectopic pregnancy is one in which a fertilized egg implants outside of the uterus, usually in the fallopian tubes. These pregnancies cannot be carried to term because only the uterus can provide the necessary environment for fetal growth. Medical professionals estimate that roughly 1-2% of all pregnancies are ectopic, and more than 90% of these occur in the fallopian tubes. Less often, ectopic pregnancies may develop in the ovaries, cervix, or even the abdominal cavity.

As the pregnancy advances, the damaged tube can burst, causing extensive internal bleeding. This is a medical emergency requiring immediate surgery.

Dr. Monica Gupta, Consultant in Obstetrics and Gynecology, clarifies, "An ectopic pregnancy is a serious condition as the pregnancy cannot survive, and there is a high risk of internal bleeding, which can be fatal."

Early Symptoms of Ectopic Pregnancy

The early warning signs of an ectopic pregnancy might be subtle and confusing, simulating early signs of pregnancy, so it can be difficult to detect. Nevertheless, there are some crucial warning signs that must be evaluated immediately:

Vaginal bleeding: It can be light spotting or more significant bleeding other than a normal menstrual period.

Abdominal pain: Sustained or severe pain in the lower abdomen or pelvic region, usually on one side.

Loose stools and abdominal discomfort: Gastrointestinal disturbances, such as diarrhea and pressure in the rectum, may be a sign of a more developed ectopic pregnancy.

Dizziness and syncope: Internal bleeding causes hypotension that leads to feelings of lightheadedness or passing out.

Pain in the shoulder: This abnormal symptom might appear if blood from a ruptured ectopic pregnancy irritates the diaphragm.

Dr. Gupta points out, "Symptoms of ectopic pregnancy can be vague and difficult to differentiate from normal pregnancy, especially in early stages before tubal rupture begins." This is the reason women who have any of the aforementioned symptoms need to undergo medical examination without hesitation.

Who Is at Risk for an Ectopic Pregnancy?

Although an ectopic pregnancy can occur in any woman, there are some risk factors that can make this condition more likely:

Previous ectopic pregnancy: A history of ectopic pregnancy greatly increases the risk of recurrence.

Pelvic inflammatory disease (PID): Infection can lead to scarring of the fallopian tubes, preventing the passage of the fertilized egg.

Previous tubal surgery: Operations including tubal ligation (tying the tubes) or operations for endometriosis may predispose to it.

Use of fertility treatments: Women who have had in vitro fertilization (IVF) are at increased risk of ectopic implantation.

Smoking: Use of tobacco is associated with fallopian tube damage.

Use of IUD at conception: Though uncommon, an intrauterine device (IUD) at the time of conception may raise the risk.

Age more than 35 years: Women older than this age group have a slightly increased risk of ectopic pregnancy.

Notably, as many as 50% of ectopic pregnancies happen in women with no identifiable risk factors, which underscores the importance of caution among all pregnant women.

Why Ectopic Pregnancy Is a Medical Emergency

A growing pregnancy needs room to expand, but fallopian tubes do not have the capacity to stretch like the uterus. If an ectopic pregnancy goes undiagnosed, the tube may rupture, causing heavy internal bleeding, shock, and death if untreated.

Dr. Gupta describes, "In advanced stages, patients have severe abdominal pain, fainting, anemia, a drop in blood pressure, and shock. If rupture happens, immediate surgery is required."

How Is an Ectopic Pregnancy Diagnosed?

Early diagnosis is critical in treating an ectopic pregnancy. Physicians employ the following methods:

Pregnancy test: A positive pregnancy test with abnormal symptoms is suspicious.

Pelvic examination: Physicians can sense tenderness, a mass, or abnormal fullness in the pelvis.

Ultrasound scan: Transvaginal ultrasound can establish the lack of pregnancy in the uterus and detect its location elsewhere.

Blood tests: Testing for levels of hCG (human chorionic gonadotropin) can diagnose abnormal pregnancies.

Treatment Options for Ectopic Pregnancy

The treatment depends on the stage at which an ectopic pregnancy is diagnosed:

Medication: If caught early, methotrexate, a drug that halts cell development, can be administered to dissolve the ectopic tissue without surgery.

Surgery: In the event the condition has progressed or rupture has already happened, immediate surgery must be done to remove the pregnancy and repair or eliminate the affected fallopian tube. This is usually done laparoscopically (minimal invasive procedure).

Ectopic pregnancy is a life-threatening condition, and early diagnosis makes a big difference in outcomes. Any woman with unusual pain, bleeding, or gastrointestinal symptoms during early pregnancy must be evaluated immediately.

Dr. Gupta emphasizes, "A suspicion of ectopic pregnancy should always be made when a patient comes with abnormal bleeding or pain during early pregnancy. Delay in diagnosis can result in serious complications."

Pregnancy should be a time of joy, but unexpected complications can arise. If you are pregnant and experience persistent abdominal pain, loose stools, dizziness, or unusual bleeding, consult a healthcare provider without delay. Ectopic pregnancy is a serious but treatable condition when diagnosed early. Raising awareness and understanding the warning signs can save lives.

Dr Monica Gupta is a Consultant Obstetrics and Gynaecology at Manipal Hospital, Bhubaneshwar In India

A recent study published in JAMA Network Open reveals that pregnant individuals facing food insecurity are at a higher risk of complications such as preeclampsia and gestational diabetes. The analysis, based on data from over 19,300 pregnant Kaiser Permanente Northern California members, found that those receiving food assistance did not face the same increased risks. The findings highlight the importance of food assistance programs in ensuring better maternal and infant health outcomes.

Study Reveals Link Between Food Insecurity and Pregnancy Complications

The study examined pregnant individuals who were screened for food insecurity—defined as running out of food or worrying about running out due to financial constraints. Key findings include:

• 14% (about 2,700 participants) experienced food insecurity during pregnancy.
• 7.6% (1,470 participants) received food assistance while pregnant.
• Higher rates of gestational diabetes (10.9% in food-insecure individuals vs. 7.9% in those without food insecurity).
• Increased risk of preeclampsia (8.1% vs. 6.3%).

Other complications such as preterm birth and neonatal ICU admission were also more common in food-insecure pregnancies.

No significant link was found between food insecurity and gestational hypertension or Caesarean delivery.

How Does Food Insecurity Affect Pregnancy?

Poor Nutrition and Diet Quality

Lack of access to nutritious food may lead to an unbalanced diet, increasing the risk of pregnancy-related conditions like gestational diabetes and high blood pressure disorders.

Inconsistent Eating Patterns

Skipping meals or irregular eating habits can affect blood sugar regulation and overall maternal health.

Psychological and Physical Stress

The stress of worrying about food availability can contribute to inflammation, hormonal imbalances, and other health risks during pregnancy.

Food Assistance Can Reduce Health Risks

Unlike food-insecure participants, those who received food aid did not experience the same increase in complications. This suggests that food assistance programs play a crucial role in mitigating the health effects of food insecurity.

The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) was the primary source of food assistance for study participants. In 2022, WIC provided benefits to 6.31 million pregnant and postpartum individuals, infants, and children, according to the U.S. Agriculture Department.

Recommendations: Improving Food Security in Pregnancy

Experts emphasize the need for better screening and policy improvements to address food insecurity among pregnant individuals. The study suggests:

• Routine screening for food insecurity during prenatal visits.
• Increased funding and accessibility for food assistance programs like WIC.
• Public health initiatives to ensure pregnant individuals have consistent access to nutritious food.

Food insecurity during pregnancy is linked to increased risks of gestational diabetes, preeclampsia, and other complications. However, food assistance programs can help reduce these risks, emphasizing the importance of expanding access to such resources. Ensuring that all pregnant individuals have access to adequate nutrition is essential for improving maternal and infant health outcomes.