How Antimicrobial Resistance Threatens Neonatal Mortality Rates Globally
Neonatal mortality remains a major health challenge across the world, which involves neonatal sepsis and other related factors of prematurity. Though many strides have been done in reducing NMR, there is a need for more appropriate interventions and strategies directed towards addressing the rise in the escalation of AMR. Combating AMR will be critical in improving neonatal survival rates while giving each newborn a healthier start into life globally.
The newborn period is the key period for infant health, and the first 28 days of life are critically important-both for survival and as a base to set lifetime health and development. Neonatal deaths globally have witnessed a significant decline over the past couple of decades. The neonatal mortality count has significantly reduced dropping from a high of 5 million in 1990 to as low as 2.3 million as of 2022. However, this decline notwithstanding, neonatal mortality is still staggeringly high across low-and middle-income nations.
Neonatal mortality rates are 22 per 1000 live births in India. Neonatal sepsis and prematurity are the main causes of neonatal deaths in these tragic events. Recognizing the gravity of the issue the Indian government started the Indian Newborn Action Plan (INAP) in 2014. The goal is to take NMR down to the single digits by 2030. This initiative has brought in several key interventions, including antenatal care (vaccines, micronutrient supplementation), skilled birth attendance, clean birth practices, and neonatal resuscitation techniques. More promisingly, postnatal interventions, including early initiation of breastfeeding and skin-to-skin contact, have been proven to work well in improving newborn survival rates.
Despite these improvements, one of the biggest concerns in neonatal care today is the growing problem of antimicrobial resistance (AMR) which seriously threatens efforts to reduce neonatal mortality.
Antimicrobial resistance occurs when microorganisms such as bacteria, viruses and fungi evolve over time and become resistant to commonly used antibiotics and other medications. This resistance makes infections more difficult to treat, increasing the risk of mortality and complicating treatment options. The World Health Organization has classified AMR as one of the most urgent global health threats since it not only causes death and disability but also places immense pressure on healthcare systems, significantly raising the economic burden.
The sources of AMR are many, including poor hygiene and infection control in healthcare settings, overuse and misuse of antibiotics. Contributing factors to this rapidly growing problem are antibiotic prescriptions for patient needs that do not require them and failure to complete antibiotic courses, as prescribed.
For neonates, the risk is much more vital for AMR. Neonates are particularly prone to developing infections due to their rather weak immune systems. Neonatal sepsis, severe bacterial infection, is one of the leading causes of neonate deaths and it often manifests complications when it is because of drug-resistant pathogens.
According to Dr. Apoorva Taduri, Consultant Neonatologist, "Neonatal sepsis accounts for a significant proportion of neonatal deaths, and AMR is making it worse. MDR pathogens cause around 30% of neonatal sepsis mortality globally.
Maternal health and care are also factors influencing AMR in neonates. Over-prescription of antibiotics during pregnancy increases the risk of neonatal sepsis and the development of multi-drug-resistant pathogens in newborns. This calls for prudent use of antibiotics during pregnancy and at the time of delivery. In fact, studies indicate that indiscriminate use of antibiotics in mothers has a direct impact on neonatal health, which may eventually lead to resistant infections in newborns.
One of the major issues is that the drug-resistant bacteria are causing an increasing number of healthcare-associated infections in the neonatal care settings, which include NICUs. Infections by such bacteria prove to be challenging to treat; they require more advanced, expensive interventions, and the period of risk of mortality and morbidity is extended.
To combat AMR and reduce neonatal mortality a multifaceted approach is necessary. Dr. Taduri emphasizes the continuation of the strategies outlined by the Indian Newborn Action Plan (INAP), specifically in reducing neonatal sepsis and improving infection control. However, to combat AMR more must be done to ensure proper use of antibiotics in both maternal and neonatal care settings.
Key strategies for reducing AMR in neonatal care are:
1. Improving Infection Prevention Practice: This implies, therefore, that more efforts would be made regarding stricter hospital hygiene standards, strict equipment sterilization after its usage and even maintaining adequate hand hygiene. Enhanced infection control practices greatly impact minimizing AMR pathogens distribution.
2. Antibiotic Stewardship- Teaching the healthcare providers how not to use antibiotics is a crucial thing in preventing overuse prescription. Antibiotic stewardship programs are designed to promote use of antibiotics only when truly required; appropriate drug, dose and length of treatment should be taken.
3. Improved access to WASH: Access to clean water and sanitation is a fundamental aspect of preventing infections in mothers and newborns. WASH interventions such as clean birthing practices, can reduce the risk of neonatal sepsis due to unsanitary conditions.
4. Maternal Health Strengthening: Proper maternal care, such as proper vaccination, antenatal steroids, and supplementation of micronutrients, can reduce the risk of prematurity and neonatal infection. Prevention of infection in mothers is the first step towards prevention of infection in newborns.
5. Early Diagnosis and Treatment: Early identification and treatment of neonatal infections are very important. This includes proper screening for sepsis and the use of appropriate antibiotics based on the local resistance patterns. It also involves ensuring that infants receive adequate neonatal care, such as those provided in Special Newborn Care Units (SNCUs).
The rise of antimicrobial resistance is a global health challenge that requires urgent action. Combating AMR requires a coordinated effort from governments, healthcare systems and communities worldwide. In neonatal care, addressing AMR is essential to further reducing neonatal mortality rates and ensuring that every newborn has the opportunity to thrive.
As Dr. Taduri concludes, "While we have made substantial progress in reducing neonatal mortality, the emerging risk of antimicrobial resistance creates a major challenge for our efforts. Combating AMR requires a global collective effort, with priorities on infection prevention, responsible use of antibiotics, and enhancement of healthcare practices to ensure a healthier future for all newborns."
Dr Apoorva Taduri is a Consultant Neonatologist at Fernandez Hospital
Credits: Canva
Men's health is a topic often not talked about, however, it is as important as any other health related topics that are addressed more frequently. This is the case especially when it comes to men's reproductive health. While there has a been a lot of studies around semen production and what makes a sperm healthy, there are still many myths around it.
To burst one of such myths, we spoke to Dr Beena Muktesh, Senior IVF Expert at Motherhood Hospital, Gurugram. We asked her whether there was any truth in the claim that semen production is linked to healthy sperm.
Dr Muktesh points out that while sperm-related problems are rampant in men, many men still assume that producing semen automatically indicates fertility. "However, it is a myth that needs to be addressed." She says that there is a need to understand the difference between the two.
Semen is a fluid that is released during ejaculation. It contains sperm and other substances from the male reproductive organs. The sperm is around 1 to 5% of the semen. The rest of it is a liquid called seminal plasma, this includes water, proteins, enzymes, and nutrients like fructose for energy. It Is important for reproduction by helping sperm reach and fertilize the egg. "Healthy semen is pivotal when it comes to male fertility. However, a common myth among men is that if they ejaculate normally, their sperm must be healthy and fertile," she points out.
The doctor says that while semen production is sign that the reproductive system is functioning, it may not guarantee that the sperm it contains are capable of fertilizing an eff.
Dr Muktesh says, "Fertility depends not just on the presence of sperm but on their count, motility or movement, and morphology, or shape. Though many women do not know about this fact and continue to struggle in silence."
Semen that appears normal is volume, color and consistency, could still contain sperm that are low in number. They could move poorly, or have structural abnormalities, pointed out the doctor. "These factors impact the ability of sperm to reach and fertilize an egg, making conception difficult even if ejaculation occurs regularly."
The doctor suggests that men must undergo a semen analysis to evaluate their fertility. The analysis will be able to tell the number of sperm in a given volume of semen.
"Low count can reduce the chances of fertilization. The sperm motility will be checked to know how the sperm will move. Poor motility means sperm may struggle to reach the egg. The expert will also pay attention to the sperm shape and structure. Abnormal shapes can affect the ability to penetrate and fertilize the egg, and make conception challenging," she points out.
There are also other factors like the semen pH, volume, and white blood cell presence that could be monitored to detect infections or other underlying concerns. This is why it is important to get the analysis done and not just assume, she points out.
"Awareness and early evaluation allow timely intervention, increasing the chances of conception and promoting informed decisions about reproductive health. So, men, consult the expert without any delay and know about your sperm health status for healthy conception," she says.
It’s almost a reflex action now - your teen seems distracted, moody or defiant and the first thing you reach for is their phone. Many parents believe that once the phone is gone, their child will start behaving better, focusing more and feeling calmer. But psychologists say this approach may be oversimplifying a complex emotional landscape.
Teenagers today are navigating a world far more layered than the one their parents grew up in. Their phones are not just gadgets, they are extensions of their identity, their social life and even their coping mechanisms. When parents link every behavioural problem to 'too much screen time' teens feel misunderstood and invalidated.
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“I am tired of being told that if I stop using my phone, I will feel better. My phone isn’t the problem, it’s how I connect with friends and keep up with what’s happening around me. Why should the rules be different for adults and for us?" says 16-year-old G. Kaur
This sentiment echoes across many teenage households - the need to be heard rather than judged. Their brains are still developing, firing signals of independence and identity formation, which often clash with parental control.
For many parents, taking away the phone feels like the only available disciplinary tool. “Whenever I feel helpless about my son’s behaviour, my instant reaction is to taunt him about his phone usage or take it away,” admits one mother. “I know it is not right, but I don’t know what else to do. We grew up without phones and turned out fine but today’s kids just can’t seem to focus.”
This response, psychologists say, stems from fear and frustration. The digital world is unfamiliar territory for many parents, and snatching the phone feels like regaining control. But in reality, it often deepens the disconnect between parent and child.
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First and foremost, understand the role of the phone. For teens, phones serve as social lifelines, a place where they explore identity, friendship and belonging. Dismissing that entirely can make them feel isolated. So instead of taking the phone away, have open conversations about how and why they use it.
Next focus on connection, not control. Rather than imposing blanket bans, set boundaries. For instance, agree on screen-free times during meals or before bed but let your teen be part of the decision-making. This gives them a sense of respect and control.
Also, look for the real reason behind behaviour. Irritability, withdrawal or lack of focus may not always be caused by phone use. These could be signs of stress, anxiety or emotional overwhelm.
Model healthy digital habits yourself. Teens mirror adult behaviour. If they see you constantly checking emails or scrolling late at night, they will assume it’s normal.
Keep an open communication. Teens respond better to empathy than authority. Simple statements like “I understand it’s hard to disconnect, even for me sometimes” or “I want to know what’s stressing you out” can make way for honest conversations.
In the end, parents need to understand that phones are not the enemy, disconnection is. When parents focus solely on controlling screen time, they risk missing the deeper emotional needs of their teens. Instead of snatching the phone, try reaching for understanding.
After all, the goal isn’t to raise a child who lives without a phone, it’s to raise one who can live well with it.
(Credit-Canva)
A new study showed that teens who begin using cannabis before the age of 15 are much more likely to face health problems later in life. Statistics show that many teens use cannabis, or substance more commonly known as weed from a young age.
The data from Government of Canada shows that 1 in 6 children from grades seventh to 12th reported using cannabis in 2014-15. They assessed that Canadian adolescents have the highest rates of cannabis usage.
The usage of cannabis at such a young age has also been linked to higher risk of using drugs later in life, according to the new study published in the JAMA Network Open. Compared to their peers who didn't use the drug in adolescence, they also face an increased risk of developing mental and physical health problems in young adulthood.
This important conclusion comes from a recent study published in a science journal called JAMA Network Open. The researchers used data from a long study in Canada called the Québec Longitudinal Study of Child Development, where they have been following more than 1,500 children from when they were infants into their young adult years.
The scientists recorded many details about their lives, including if they used cannabis between the ages of 12 and 17. The study sorted the teenagers into three groups based on their habits:
Most of the teenagers didn't use cannabis at all during their adolescence.
These teens started using cannabis later (in their late teens) and only used it rarely—less than once a month—by the time they were 17.
This last group started using cannabis before age 15 and used it at least once a month by age 17.
The group of teens who started early and used often was much more likely to visit the doctor or seek care for both mental and physical health problems as young adults.
These early/frequent users had a 51% higher chance of seeking professional help for mental health issues. This risk was calculated to be real even after the researchers carefully removed the influence of other factors that can affect health, like being bullied or problems at home.
Similarly, the same early and frequent users had an 86% higher chance of needing care for physical problems. The most common physical issues they reported were respiratory issues and getting into accidents or unintentional injuries. These issues could be related to being high/intoxication or perhaps to the body reacting when they stop using the drug, which are known as withdrawal symptoms.
The Center of Disease Control and Prevention (CDC) explained that the brain of a teenager is still growing and developing a lot, and this process continues until they are about 25 years old. Using cannabis (marijuana) during the teen years and young adulthood can potentially harm this development.
Compared to teens who don't use cannabis, those who do are more likely to drop out of high school or not finish a college degree. Using cannabis can cause several immediate and long-term problems for teens
Cannabis is linked to depression and anxiety, and it raises the risk of temporary psychosis (paranoia or hallucinations). Starting young and using often increases the likelihood of long-term illness like schizophrenia.
Driving under the influence of cannabis is illegal and unsafe, as it severely slows reaction time. Cannabis reduces coordination and concentration, impacting all the skills necessary for responsible and safe driving.
Around 30% of cannabis users develop an addiction (cannabis use disorder). Failing to quit or choosing the drug over family activities are signs. This risk is higher for frequent teen users.
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