How Antimicrobial Resistance Threatens Neonatal Mortality Rates Globally
Neonatal mortality remains a major health challenge across the world, which involves neonatal sepsis and other related factors of prematurity. Though many strides have been done in reducing NMR, there is a need for more appropriate interventions and strategies directed towards addressing the rise in the escalation of AMR. Combating AMR will be critical in improving neonatal survival rates while giving each newborn a healthier start into life globally.
The newborn period is the key period for infant health, and the first 28 days of life are critically important-both for survival and as a base to set lifetime health and development. Neonatal deaths globally have witnessed a significant decline over the past couple of decades. The neonatal mortality count has significantly reduced dropping from a high of 5 million in 1990 to as low as 2.3 million as of 2022. However, this decline notwithstanding, neonatal mortality is still staggeringly high across low-and middle-income nations.
Neonatal mortality rates are 22 per 1000 live births in India. Neonatal sepsis and prematurity are the main causes of neonatal deaths in these tragic events. Recognizing the gravity of the issue the Indian government started the Indian Newborn Action Plan (INAP) in 2014. The goal is to take NMR down to the single digits by 2030. This initiative has brought in several key interventions, including antenatal care (vaccines, micronutrient supplementation), skilled birth attendance, clean birth practices, and neonatal resuscitation techniques. More promisingly, postnatal interventions, including early initiation of breastfeeding and skin-to-skin contact, have been proven to work well in improving newborn survival rates.
Despite these improvements, one of the biggest concerns in neonatal care today is the growing problem of antimicrobial resistance (AMR) which seriously threatens efforts to reduce neonatal mortality.
Antimicrobial resistance occurs when microorganisms such as bacteria, viruses and fungi evolve over time and become resistant to commonly used antibiotics and other medications. This resistance makes infections more difficult to treat, increasing the risk of mortality and complicating treatment options. The World Health Organization has classified AMR as one of the most urgent global health threats since it not only causes death and disability but also places immense pressure on healthcare systems, significantly raising the economic burden.
The sources of AMR are many, including poor hygiene and infection control in healthcare settings, overuse and misuse of antibiotics. Contributing factors to this rapidly growing problem are antibiotic prescriptions for patient needs that do not require them and failure to complete antibiotic courses, as prescribed.
For neonates, the risk is much more vital for AMR. Neonates are particularly prone to developing infections due to their rather weak immune systems. Neonatal sepsis, severe bacterial infection, is one of the leading causes of neonate deaths and it often manifests complications when it is because of drug-resistant pathogens.
According to Dr. Apoorva Taduri, Consultant Neonatologist, "Neonatal sepsis accounts for a significant proportion of neonatal deaths, and AMR is making it worse. MDR pathogens cause around 30% of neonatal sepsis mortality globally.
Maternal health and care are also factors influencing AMR in neonates. Over-prescription of antibiotics during pregnancy increases the risk of neonatal sepsis and the development of multi-drug-resistant pathogens in newborns. This calls for prudent use of antibiotics during pregnancy and at the time of delivery. In fact, studies indicate that indiscriminate use of antibiotics in mothers has a direct impact on neonatal health, which may eventually lead to resistant infections in newborns.
One of the major issues is that the drug-resistant bacteria are causing an increasing number of healthcare-associated infections in the neonatal care settings, which include NICUs. Infections by such bacteria prove to be challenging to treat; they require more advanced, expensive interventions, and the period of risk of mortality and morbidity is extended.
To combat AMR and reduce neonatal mortality a multifaceted approach is necessary. Dr. Taduri emphasizes the continuation of the strategies outlined by the Indian Newborn Action Plan (INAP), specifically in reducing neonatal sepsis and improving infection control. However, to combat AMR more must be done to ensure proper use of antibiotics in both maternal and neonatal care settings.
Key strategies for reducing AMR in neonatal care are:
1. Improving Infection Prevention Practice: This implies, therefore, that more efforts would be made regarding stricter hospital hygiene standards, strict equipment sterilization after its usage and even maintaining adequate hand hygiene. Enhanced infection control practices greatly impact minimizing AMR pathogens distribution.
2. Antibiotic Stewardship- Teaching the healthcare providers how not to use antibiotics is a crucial thing in preventing overuse prescription. Antibiotic stewardship programs are designed to promote use of antibiotics only when truly required; appropriate drug, dose and length of treatment should be taken.
3. Improved access to WASH: Access to clean water and sanitation is a fundamental aspect of preventing infections in mothers and newborns. WASH interventions such as clean birthing practices, can reduce the risk of neonatal sepsis due to unsanitary conditions.
4. Maternal Health Strengthening: Proper maternal care, such as proper vaccination, antenatal steroids, and supplementation of micronutrients, can reduce the risk of prematurity and neonatal infection. Prevention of infection in mothers is the first step towards prevention of infection in newborns.
5. Early Diagnosis and Treatment: Early identification and treatment of neonatal infections are very important. This includes proper screening for sepsis and the use of appropriate antibiotics based on the local resistance patterns. It also involves ensuring that infants receive adequate neonatal care, such as those provided in Special Newborn Care Units (SNCUs).
The rise of antimicrobial resistance is a global health challenge that requires urgent action. Combating AMR requires a coordinated effort from governments, healthcare systems and communities worldwide. In neonatal care, addressing AMR is essential to further reducing neonatal mortality rates and ensuring that every newborn has the opportunity to thrive.
As Dr. Taduri concludes, "While we have made substantial progress in reducing neonatal mortality, the emerging risk of antimicrobial resistance creates a major challenge for our efforts. Combating AMR requires a global collective effort, with priorities on infection prevention, responsible use of antibiotics, and enhancement of healthcare practices to ensure a healthier future for all newborns."
Dr Apoorva Taduri is a Consultant Neonatologist at Fernandez Hospital
Credits: iStock
For generations, childbirth has been closely tied to a certain visual and emotional script. Bright lights, clinical beds, beeping monitors, and an air of urgency have long defined labor rooms. Today, that script is being rewritten. Across hospitals and birthing centers, childbirth is undergoing a quiet but powerful aesthetic shift, one that places calm, comfort, and emotional safety at the center of the experience.
At the heart of this transformation is the growing popularity of warm water births and thoughtfully designed birthing spaces. As Dr. Preety Aggarwal, Medical Director of Obstetrics and Gynecology at Motherhood Hospitals, Gurugram explains, “From harsh hospital lights to calm, spa-like spaces, childbirth is being reimagined as a peaceful, deeply personal experience wherein tranquility takes center stage over tension.” What once felt intimidating is increasingly being shaped to feel intimate and reassuring.
Childbirth has always been transformative, but for decades, the setting often heightened fear rather than eased it. Labor rooms were designed primarily for efficiency and medical control, not for emotional comfort. That approach is now evolving. More couples are actively seeking environments that respect birth as both a physiological and emotional journey.
“Childbirth is a one-of-a-kind experience. It is deeply transforming for the mother,” the doctor notes. This understanding has prompted hospitals to rethink how birthing spaces look and feel. Neutral colous, warm lighting, wooden textures, and minimal visual clutter are replacing stark whites and harsh fluorescents. The goal is not to eliminate medical safety, but to soften its visual dominance.
The rise of warm water birthing pools fits naturally into this shift. These pools are often placed in private, dimly lit rooms that resemble wellness studios rather than hospital wards. Gentle music, controlled lighting, and calming scents further enhance the sense of control and peace.
Water has an innate ability to soothe. Immersion in warm water relaxes muscles, reduces physical tension, and encourages slower, deeper breathing. According to clinical observations, many women feel a stronger sense of control when laboring in water. The pool acts as a physical and psychological buffer, helping block out noise, distractions, and external stress.
The expert points out that water births are not only about comfort but also about reducing fear. Many mothers report feeling less anxious and more connected to their bodies during labor. This inward focus can make contractions feel more manageable and the overall experience more empowering.
Rephrasing this idea, the essence of water birth lies in its ability to support the body’s natural rhythm. Instead of fighting pain, women are encouraged to work with it, supported by warmth, buoyancy, and privacy.
One of the most common misconceptions about serene birthing environments is that they compromise safety. In reality, the shift is about balance. Modern birthing spaces are designed to keep medical equipment accessible but discreet. The focus is on emotional well-being alongside clinical readiness.
“There is a clear shift in attitude,” the doctor explains, adding that childbirth is no longer seen as just a medical event but as a life experience deserving emotional care. This change also reflects broader conversations around respectful maternity care, where the mother’s comfort, dignity, and choices are prioritized.
For expectant parents interested in this approach, preparation plays a key role. Choosing a hospital or birthing center that offers warm water birth options and calming room designs is the first step. Simple additions like soft lighting, calming music, and guided breathing techniques can make a noticeable difference.
Incorporating natural elements such as plants and warm colors helps create a grounding environment. Emotional support from a partner, doula, or trusted caregiver is equally important. A clear birth plan that balances comfort preferences with medical safety allows both parents and healthcare teams to work in harmony.
Warm water pools and serene birthing environments are changing more than the appearance of labor rooms. They are reshaping how birth is felt, remembered, and processed. By replacing tension with tranquility, this approach supports mothers in feeling calmer, more confident, and more present during one of life’s most intense moments.
As the expert advises, anyone considering this option should discuss it with their doctor and make informed decisions based on individual health needs. What is clear, however, is that the aesthetics of childbirth are no longer an afterthought. They are becoming an essential part of how birth itself is experienced, marking a meaningful shift toward gentler, more human-centered care.
Credits: iStock
Sleep training is a key to a good night's rest. This is especially true for the parents who are still new with handling their babies. One such method of sleep training, famous in Denmark is called the 'cry it out' method.
However, this method has been long in debates, Especially with one side saying that allowing babies to bawl does no harm, whereas, other sets of research and studies suggest that it impacts babies' emotional quotient. In fact, research suggest that leaving the babies to cry could have knock-on effects including damaging the bond between parent and child and raising the infant's stress levels.
However, recently, 723 Danish psychologists signed an open letter stating that cry it out sleep method, known as the "good night and sleep well" method in Denmark should be discouraged, as such methods may risk the attachment and child's development.
This is also known as the extinction method, where rather than answering your little one's crying call as soon as it goes out, you give them the opportunity to independently work it out and nod off. This method is not intended to be cruel, it is meant to be used as an intentional tool to teach your baby self-soothing techniques that will stick with them for life.
Some also call it same as going cold turkey on your child. Parenting experts say that you put your baby in their crib, say goodnight and shut the door.
A study led by researchers from the University of Warwick and published in the Journal of Child Psychology and Psychiatry, followed 178 babies and their mothers in the UK from birth to 18 months. Mothers regularly filled out questionnaires explaining how often they let their baby “cry it out” shortly after birth, and again at three, six, and 18 months.
Researchers also observed mother-infant interactions through video recordings at three and 18 months. At 18 months, they assessed children’s behavior and attachment using parent questionnaires, psychologist reports, and observations of play.
The results showed that most mothers rarely let newborns cry. However, by 18 months, around two-thirds allowed their child to cry sometimes or often. Importantly, babies who were occasionally allowed to cry as newborns tended to cry for shorter periods by 18 months.
The team found no negative effects on the child’s emotional attachment, behaviour, or the mother’s sensitivity by 18 months. Based on these findings, researchers concluded that the practice does not appear to cause harm.
Professor Dieter Wolke, a co-author of the study, said parents may have worried unnecessarily about the issue. He suggested that debates around crying may have been exaggerated.
Not everyone agrees that the findings settle the debate. Professor Amy Brown from Swansea University, who was not involved in the research, warned that the results should be interpreted carefully. She noted that very few mothers in the study regularly used the “cry it out” approach, and the study did not examine how long babies were left to cry or how distressing parents found the experience.
She also emphasized that the research does not prove controlled crying is beneficial, nor does it address the emotional toll it can take on caregivers.
Some researchers highlight concerns about stress in early life. A baby’s brain grows rapidly in the first year, and intense distress triggers the release of cortisol, a stress hormone. In high levels, cortisol may harm developing neural connections. While the effects may not be immediate, some experts question whether repeated distress could have long-term consequences.
Infants rely on caregivers to learn how to regulate emotions. When caregivers respond quickly and consistently, babies learn calmness and trust. Comforting a distressed baby helps build the foundation for self-soothing later in life.
Critics argue that leaving babies to cry may teach them to shut down emotionally rather than truly self-regulate. Over time, this could affect how children respond to stress and relationships.
Decades of developmental research show that caregiver responsiveness plays a crucial role in positive outcomes such as emotional regulation, social skills, empathy, and even intelligence. When caregivers are sensitive to a baby’s signals, it supports healthy brain and emotional development.
Because responsiveness is so influential, experts stress that any parenting approach should prioritize attentiveness to a child’s needs. While occasional crying may not be harmful, consistent care and emotional availability remain central to healthy development.
Credits: Canva
A 16-year-old mother in Peru delivered a baby who was in placenta that attached to her liver.
This is a rare milestone as the baby has been safely delivering from an abdominal ectopic pregnancy in which the placenta was attached to the mother’s liver.
The case involved 19 year old Valeria Vela, whose pregnancy continued to 40 weeks and resulted in the birth of a healthy baby girl. Health authorities in Peru say this is the first documented case of its kind in the country and only the fourth reported worldwide in which both mother and baby survived.
Ectopic pregnancies occur when a fertilized egg implants outside the uterus. In most situations, they develop in the fallopian tubes.
Around 96 percent of ectopic pregnancies happen there and only a very small number occur in the abdominal cavity. These pregnancies cannot safely continue because the organs where the egg may attach are not designed to support a growing fetus. In this case, the egg implanted directly on the liver, which meant the fetus relied on the liver’s arteries for blood supply. This created a situation that demanded extremely careful monitoring, as even small shifts in blood flow could have been dangerous.
For doctors, the biggest challenge was the placenta. Removing a placenta that has attached itself to the liver can cause severe bleeding that can quickly turn fatal. Peru’s Health Minister Luis Quiroz Avilés explained that any attempt to detach it without preparation could have caused life threatening hemorrhage in the mother.
To manage this, the medical team used a technique that closes the arteries feeding the placenta by blocking their blood flow. This approach helped prevent massive bleeding during surgery and gave both mother and baby a chance at survival.
Another extraordinary aspect of this case was that the pregnancy reached 40 full weeks. Previous live abdominal ectopic pregnancies that resulted in birth reached only up to 36 weeks. Doctors followed Valeria closely through her pregnancy and relied on advanced imaging and interventional radiology techniques to keep the situation stable. According to local reports, the clinical management required constant coordination among specialists from obstetrics, radiology, surgery and intensive care.
The baby, named Aylin, was born on November 30 and weighed 7.9 pounds. Officials revealed the case only after both mother and child were safely discharged from the hospital. Valeria is now in stable condition and recovering well, while Aylin is reported to be healthy.
Although the case has been described as a medical milestone, specialists emphasize that such pregnancies are exceptionally rare. Most ectopic pregnancies cannot continue and trying to carry them comes with severe risks that include hemorrhage, organ damage and even death. For this reason, early diagnosis and timely intervention remain the safest and most widely recommended approach. This case highlights what is medically possible under very specific circumstances, but it does not change established guidelines for managing ectopic pregnancies.
© 2024 Bennett, Coleman & Company Limited