The year that just went by, was obsessed with Ozempic and weight loss. Not just that, but it was also the most searched weight loss drug outpacing Wegovy, its closest competitor, by 300%. As of November 2024, it had a current volume of 16 million searches per month.

What is Ozempic?

Ozempic or semaglutide s a prescribed drug that is used in people with type 2 diabetes. It is given as an injection under your skin and could be prescribed off-label for weight loss. However, the drug is not approved by Food and Drug Administration (FDA) for weight loss.

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The active ingredient in this is semaglutide, which belongs to the class of drugs called glucagon-like peptide-1 or GLP-1 receptor agonists. This is what helps stimulate pancreas to release insulin, prevents, cravings and hunger pangs and prevents increase in blood sugar. It basically mimics the action of naturally produced hormones GLP-1 by activating GLP-1 receptors to achieve these results.

However, it does not come without any side effects. They can include nausea, stomach pain, constipation, thyroid cancer, and more.

But, what if we tell you that you can try these foods which mimic the results of Ozempic, without these above mentioned side effects?

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Filling Foods

These foods are called filling foods, that make you feel full and thus controls your cravings. These are foods high in protein, fiber, and healthy fats which can trigger the release of GLP-1 hormones and other satiety-enhancing effects. Another reason to consider it? These are cheaper than the medications and do not have the unwanted side effects.

Foods that mimic Ozempic effects

Oats: They are rich in soluble fiber called beta-glucan. This can delay gastric emptying and promote feelings of fullness. As per a study published in Current Nutrition Reports, the beta-glucan increases satiety and reduces energy intake by enhancing GLP-1 secretion.

Studies also show that oats can help lower body weigh and harmful LDL- cholesterol levels.

Barley: This also contains beta-glucan, so the effects remain same. Furthermore, the journal Nutrients reported that barley lowered a hunger hormone called leptin.

Legumes, beans, lentils, chickpeas: In one study that included more than 15,000 U.S. adults published in the journal Nutrients found that legume intake was inversely associated with weight gain over the 10-year study period. Adults in the study with moderate to high intakes gained substantially less weight over the past decade than those reporting no legume intake.

Eggs: A study published in Nutrition Research reported that those who had eggs for breakfast reduced overall caloric consumption for the entire day.

Greek Yogurt: It is a healthy, must-have in your diet as it helps you stay fuller longer and also helps with your gut health. Studies suggest that the protein coupled with probiotics enhances satiety and impacts your appetite-regulating hormones to keep your hunger and cravings in check.

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Avocado: They are rich in monounsaturated and polyunsaturated fats, which are considered heart healthy. Avocados are also rich in dietary fiber. A medium-sized avocado has 10 grams of fiber, or more than half the fiber you need in a day. The high fat and fiber content of avocados leads to slower digestion, lower blood sugar and insulin levels and elevates hormones levels that trigger fullness.

Fish: The long-chain omega-3 fatty acids in fish along with the high-quality protein help down-regulate your hunger and appetite.

While the World Health Organization recommends 5g or a tablespoon of salt every day, Indians consume more than double, increasing their risk of having a fatal stroke exponentially.

According to EatRightIndia, Indians consume about 11g of salt each day through meals which can significantly increase their risk of high blood pressure, strokes and hypertension.

Hypertension causes over 1.6 million deaths annually, accounting for nearly 18 percent of all fatalities and heavily contributes to deaths caused by heart disease, stroke and kidney disease.

What Is Excessive Salt Dangerous?

The most important side effect of consuming excessive salt intake is high blood pressure. Salt causes the body to retain water, increasing the volume of blood in your vessels and leading to elevated pressure levels. If your blood pressure consistently measures over 140/90 mmHg, it's time to evaluate your salt consumption.

Over time, this can rapidly raise your risk for heart disease, stroke while also potentially contributing to stomach cancer and weakened bones. Additionally, high blood pressure damages kidneys and excess sodium can lead to kidney stones or disease.

Apart from a 5gm recommendation for adults, NHS suggests that children between seven to 11 years of age should not eat more than 5g of salt while those between four to six years of age should eat less than 3g of salt every day to maintain heart health.

How Can You Reduce Your Salt Consumption?

Both excessive and insufficient salt intake have been linked to adverse outcomes. Achieving the right balance is critical, and the best approach is to minimize processed food consumption rather than relying solely on the salt shaker.

Common items such as pickles, paapads, chutneys, salads and buttermilk significantly contribute to daily salt consumption. Hidden salts in packaged goods like biscuits, sauces, condiments and snacks also can increase your salt intake.

To cut down on your salt intake, experts recommend:

• Not adding salt in rice and dough for chapati, poori and paratha.
• Not sprinkling salt on salad, cut fruits, cooked vegetables or curd.
• Gradually reducing the salt usage while cooking from lesser to least.
• Limit food accompaniments like salted butter, salty spice mixes (chaat masala, jal jeera masala etc.), chutneys, pickles, ketchups, sauces and dressings as they contain excess salt.
• Baking soda, baking powder, and monosodium glutamate (MSG) also contains high sodium and should be avoided in your daily cooking.
• Not keeping salt on the table.
• Buying tinned vegetables, pulses or fish in water instead of brine.
• Being aware that some dissolvable tablets, such as painkillers, vitamins or prescription medicines, may be high in salt.

Tagatose, a natural sugar with a third of the calories of table sugar, may be the up-and-coming safe alternative to unhealthy added sugars, scientists say.

Researchers from Tufts University, Massachusetts in partnership with biotechnology companies Manus Bio (US) and Kcat Enzymatic (India), claim that tagatose, found in only small amounts in some dairy products and fruits, is a healthier option than regular sugar and sweeteners.

The experts also claim it this rare natural sugar also does not cause insulin spikes, making it safe for consumption for both Type 1 and 2 diabetes patients. Tagatose has also been previously recognized as safe for consumption by the US Food and Drug Administration (FDA) and the World Health Organization (WHO).

Certain studies have also found tagatose to be 'tooth friendly', as it can limit the growth of harmful microbes in the dental cavity and prevent tooth decay as well as cavities.

How Is Better Than Other Artificial Sweeteners?

Due to being a natural sugar with similar taste and bulk to sugar but fewer calories, minimal blood sugar impact, prebiotic benefits and heat-stable for baking, tagatose is known to better than artificial sweeteners.

Moreover, it also lacks the bitter aftertaste common with some artificial sweeteners such as saccharin and stevia and tastes 92 percent as sweet and 60 percent less calories than common sugar.

With low calories and low absorption, tagatose is an attractive bulk sweetener, meaning it can not only can replace sugar for sweetness but can also provide a similar bulk texture in cooking that comes with adding the sugar in some quantity, something that high intensity sweetener substitutes are unable to do due to their composition.

Can Diabetes Patients Consume It?

Yes, tagatose can be eaten by insulin-resistant people as it's only partially absorbed in the small intestine; much of it being fermented by gut bacteria in the colon. Because of this, its impact on blood glucose and insulin is much less than that of conventional sugar.

Clinical studies show very low increases in plasma glucose or insulin after ingestion of tagatose. However, in the gut, the rare sugar is metabolized in a similar way to the fruit sugar, fructose, meaning those with fructose intolerances may want to steer clear

Where Can I Buy It?

While tagatose is far more beneficials than other commercially-available sugars, it remains unavailable due to limited production. "There are established processes to produce tagatose, but they are inefficient and expensive," explains biological engineer Nik Nair from Tufts.

But it can still be found in milk and other dairy products when lactose is broken down by heat or enzymes, such as yogurt, cheese and kefir. Along with this, fruits such as apples, pineapples and oranges also contain trace levels of tagatose as part of their natural carbohydrate spectrum.

Cancer cells do use oxygen to metabolize sugar(glucose) to generate energy for their sustenance. They use anaerobic respiration i.e. glycolysis. Cancer still remains a prominent cause of mortality across the globe. Despite recent breakthroughs in the treatment strategies, the understanding of how cancer begins inside a cell remains elusive.

Traditional treatment pathways such as chemotherapy, radiation therapy and even surgery, although inevitable, are still falling short in effectively eradicating certain malignancies. In many cases, they aren’t fully able to restrict the disease progression, causing systemic toxicity which further can have its own complications.

However, we find ourselves in an interesting place where growing research is making us look at cancer in newer ways. For the first time, cancer is being considered as having metabolic irregularities as a major cause in addition to genetic aberrations. This might change the way we treat the disease in the coming days.

Cancer cells breathe differently

Interestingly, new age theories are observing some commonality among all cancers, the affected cells generate energy differently.

Cancer cells are not using oxygen to generate energy. Instead, they are fermenting glucose and glutamine (an amino acid found in the body) to fuel their growth. This impaired cellular respiration might be at the core of disease formation.

Dr Thomas Seyfried (a leading proponent of the metabolic theory of cancer) has gone ahead in saying that infected mitochondria (powerhouse of the cell) is the propeller of the disease and not the nucleus (where genetic material is stored inside a cell). It might be the kitchen of the cells that is calling the shots.

Starving cancer cells could be a way forward

Healthy human cells can use liver-generated ketone bodies for energy production in the absence of glucose. However, cancer cells are incapable of fermenting ketone bodies.

If tumors thrive on glucose and glutamine, removing these fermentable fuels can enable starvation of cancer cells. They can easily shrink or even disappear. On the flip side, chronically elevated blood glucose can contribute to the progression of the disease.

Growing research propagates the induction of a ‘calorie-restricted’ diet for both prevention and management of cancer.

It is being observed that therapeutic ketosis using carbohydrate-restricted diets alongside traditional treatments (chemotherapy, surgery et al) is showing clinically positive results in cancer patients. In my own office, I have seen similar experiences where my patients benefitted from a holistic approach to cancer treatment which included tailored low glycemic diets.

The standard treatment in form of chemotherapy, radiation and surgery are cytotoxic methodology; dietary interventions and Indian traditional medicine break the resistance of cancer cells and make them amenable to cytotoxic treatment simultaneously decreasing the adverse effects of cytotoxic treatment.

While aggressive keto diets can be a late-stage intervention, maintaining a moderately calorie-restricted diet can be adopted as a preventive measure against the rise of cancer.

Finding a middle path

Cancer researchers might have theoretical disagreements but most of them agree on the fact that there are multiple factors involved in conversion of a normal cell into a tumour. Hence, having a holistic approach to the treatment is the way forward.

While standard treatments like chemotherapy, radiation therapy and surgery are not replaceable, the systemic toxicity caused by these aggressive treatments is reduced as well as response to them is augmented using holistic approach with dietary intervention and Indian traditional medicine, under the supervision of skilled professionals.

Note: Conventional treatments like chemotherapy, radiation therapy and surgery are not replaceable, and must be continued as per the instruction of the supervising practitioner