The year that just went by, was obsessed with Ozempic and weight loss. Not just that, but it was also the most searched weight loss drug outpacing Wegovy, its closest competitor, by 300%. As of November 2024, it had a current volume of 16 million searches per month.

What is Ozempic?

Ozempic or semaglutide s a prescribed drug that is used in people with type 2 diabetes. It is given as an injection under your skin and could be prescribed off-label for weight loss. However, the drug is not approved by Food and Drug Administration (FDA) for weight loss.

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The active ingredient in this is semaglutide, which belongs to the class of drugs called glucagon-like peptide-1 or GLP-1 receptor agonists. This is what helps stimulate pancreas to release insulin, prevents, cravings and hunger pangs and prevents increase in blood sugar. It basically mimics the action of naturally produced hormones GLP-1 by activating GLP-1 receptors to achieve these results.

However, it does not come without any side effects. They can include nausea, stomach pain, constipation, thyroid cancer, and more.

But, what if we tell you that you can try these foods which mimic the results of Ozempic, without these above mentioned side effects?

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Filling Foods

These foods are called filling foods, that make you feel full and thus controls your cravings. These are foods high in protein, fiber, and healthy fats which can trigger the release of GLP-1 hormones and other satiety-enhancing effects. Another reason to consider it? These are cheaper than the medications and do not have the unwanted side effects.

Foods that mimic Ozempic effects

Oats: They are rich in soluble fiber called beta-glucan. This can delay gastric emptying and promote feelings of fullness. As per a study published in Current Nutrition Reports, the beta-glucan increases satiety and reduces energy intake by enhancing GLP-1 secretion.

Studies also show that oats can help lower body weigh and harmful LDL- cholesterol levels.

Barley: This also contains beta-glucan, so the effects remain same. Furthermore, the journal Nutrients reported that barley lowered a hunger hormone called leptin.

Legumes, beans, lentils, chickpeas: In one study that included more than 15,000 U.S. adults published in the journal Nutrients found that legume intake was inversely associated with weight gain over the 10-year study period. Adults in the study with moderate to high intakes gained substantially less weight over the past decade than those reporting no legume intake.

Eggs: A study published in Nutrition Research reported that those who had eggs for breakfast reduced overall caloric consumption for the entire day.

Greek Yogurt: It is a healthy, must-have in your diet as it helps you stay fuller longer and also helps with your gut health. Studies suggest that the protein coupled with probiotics enhances satiety and impacts your appetite-regulating hormones to keep your hunger and cravings in check.

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Avocado: They are rich in monounsaturated and polyunsaturated fats, which are considered heart healthy. Avocados are also rich in dietary fiber. A medium-sized avocado has 10 grams of fiber, or more than half the fiber you need in a day. The high fat and fiber content of avocados leads to slower digestion, lower blood sugar and insulin levels and elevates hormones levels that trigger fullness.

Fish: The long-chain omega-3 fatty acids in fish along with the high-quality protein help down-regulate your hunger and appetite.

Trying to lose weight? Drop that wheat bread loaded with carbohydrates, suggests a study, which showed that the humble staple food for people worldwide can cause weight gain even without adding extra calories.

Traditionally, research has focused on high-fat consumption as the main driver of weight gain, but the role of carbohydrate-rich foods such as bread, rice, and noodles—consumed daily around the world—is less explored.

In the study, researchers at Osaka Metropolitan University in Japan studied how carbohydrates influence eating behavior and metabolism in mice.

The researchers examined whether mice preferred foods like wheat, bread, and rice over standard chow, and how these choices affected body weight and energy use.

The animals were divided into several feeding groups, including

• Chow,
• Chow + Bread,
• Chow + Wheat flour,
• Chow + Rice flour,
• High-fat diet (HFD) + Chow,
• HFD + Wheat flour.

Mice that consumed rice flour similarly gained weight to those that ate wheat flour. In contrast, mice given a High-fat diet (HFD) + Wheat flour gained less weight than those on a High-fat diet (HFD) + Chow.

"These findings suggest that weight gain may not be due to wheat-specific effects, but rather to a strong preference for carbohydrates and the associated metabolic changes," said Professor Shigenobu Matsumura from the varsity’s Graduate School of Human Life and Ecology.

What Is Driving Weight Gain

The results showed that weight gain was not caused by "overeating," but by a reduction in energy expenditure.

Further analysis revealed higher levels of fatty acids in the blood and lower levels of essential amino acids. In the liver, fat accumulation increased, along with the activity of genes linked to fatty acid production and lipid transport.

When wheat flour was removed from the diet, both body weight and metabolic abnormalities improved quickly. This suggests that moving away from a wheat-heavy diet and toward a more balanced one may help regulate body weight more effectively.

While the study was conducted in mice, the researchers aim to focus on humans “to verify the extent to which the metabolic changes identified in this study apply to actual dietary habits".

"We also intend to investigate how factors such as whole grains, unrefined grains, and foods rich in dietary fiber, as well as their combinations with proteins and fats, food processing methods, and timing of consumption, affect metabolic responses to carbohydrate intake. In the future, we hope this will serve as a scientific foundation for achieving a balance between "taste" and "health" in the fields of nutritional guidance, food education, and food development," stated Professor Matsumura.

Oats for breakfast are a go-to choice for many health enthusiasts. Celebrities often turn to this source of complex carbohydrates to kick-start their day—but research suggests some health benefits of this breakfast food that are often overlooked. According to a study by the University of Bonn, eating oats for just two days can help reduce cholesterol levels naturally, and the benefits can last for weeks afterwards. The study, published in the Nature Communications journal, found that even short-term dietary changes can contribute to improvements in people’s risk of metabolic diseases. Experts say that such studies reinforce the importance of following a healthy diet for heart health.

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What makes oats a healthy breakfast choice?

Oats are rich in soluble fibre and beta-glucans, and these nutrients make them good for cholesterol management and heart health. Experts say that while two days of oats can benefit the heart, it is important to follow a long-term dietary regime to maximise the benefits. Researchers noted that oats can improve cholesterol management by altering the gut microbiome. They help produce compounds that boost metabolism, such as ferulic acid. At the same time, oats help reduce insulin resistance, which is a driving factor for diabetes.

How do oats improve heart health?

In the trial, participants who were suffering from metabolic syndrome followed an oat-based diet for two days—about 300 mg per day. This was divided into three meals along with portions of fruits and vegetables. The results were:

1. Weight loss of 2 kilos
2. LDL dropped by 10 per cent
3. Benefits sustained after six weeks
4. Blood pressure also improved

A control group also followed a calorie-restricted diet, and the improvements noted were greater compared to people who consumed oats.

Are two days sufficient to reap the benefits of oats?

The study found that a high-intensity oat diet had stronger effects compared to a longer and moderate intake. It was found that people who ate 80 grams of oats for six weeks showed minor improvements compared to those who followed the strict two-day plan. This suggests that a structured dietary intervention, even if short, can deliver faster metabolic results.

Nutrition in oats

Oats contain some protein but are primarily rich in soluble fibre, beta-glucans, and complex carbohydrates. One cup of oats can provide about 4–6 grams of fibre. To enhance the nutritional value and benefits of oats, you can also add fruits and vegetables.

Conclusively, it can be said that diet can have a strong impact on heart health, especially if one makes informed choices. However, experts warn against relying on short-term solutions for long-term care. Particularly in the case of patients with high cholesterol, consulting an expert is important before making dietary changes. While eating oats for just two days can be beneficial, it is advisable to follow a long-term plan to improve overall metabolic health.

Drinking hot tea or coffee can be a real source of comfort as a wake-up time ritual or a relaxing activity after work. But how hot is too hot? And could everyday habits like burning the bridge with your tea or brushing past frequent heartburn be putting you at risk for serious health problems? New research indicates that temperature and long-term irritation of the food pipe (esophagus) may be more important than many realize in the risk of cancer.

The Hidden Risk Of Very Hot Drinks

It’s not the tea or coffee, it’s the temperature. The International Agency for Research on Cancer has classified “drinking very hot beverages” (i.e., those that are consumed at greater than 65°C (149°F) as “probably carcinogenic to humans.” Repeated incidents of hot liquids in the esophagus lining can lead to damage over time.

In support of this, a meta-analysis of 39 studies totaling more than 42,000 participants, published in BMC Cancer (2015), found that hot beverages and foods were associated with a significantly higher risk of esophageal cancer, ranging from an overall increase of about 82%.

A recent prospective cohort study published in the British Journal of Cancer (2025) based on UK Biobank data has again pointed out the association of drinking very hot beverages frequently with increased risk of esophageal cancer.

What Happens Inside The Body?

The mechanism is simple but scary. Repeatedly consuming very hot liquids can damage the fragile lining of the esophagus, through repeated thermal injury. Over time this repetitive damage may lead to:

• Chronic inflammation
• Increased cell turnover
• Greater likelihood of abnormal cell growth

This process can create an environment where cancer is more likely to develop.

Where Heartburn Fits In

But hot drinks are just part of the picture. Another risk factor is frequent heartburn/acid reflux - which is the back flow of stomach acid into the esophagus. Chronic exposure to acid is a risk factor for developing the condition known as Barrett’s esophagus, which has a higher risk of progressing to esophageal cancer.

Research published in Gastroenterology (2014) shows that long-term gastroesophageal reflux disease (GERD) is strongly associated with an increased risk of esophageal adenocarcinoma. When combined, heat damage from hot drinks and chemical irritation from acid reflux may further increase the risk.

An important point: Tea and Coffee are NOT the issue. In fact, a number of studies have shown that these drinks may have some healthy benefits due to their antioxidant content. The issue is drinking these drinks at very high temperatures.

How To Reduce Your Risk

The good news is that small changes can make a meaningful difference.

Experts recommend:

• Letting hot drinks cool slightly before sipping
• Avoiding frequent consumption of very hot liquids
• Managing heartburn symptoms early
• Seeking medical advice for persistent acid reflux

Even pausing a few minutes before sipping your tea or coffee can help cut out some of the risks. You don’t have to sacrifice your daily cup of tea or coffee for your health, but how you drink it does matter.

Scientific research indicates that chronic heartburn and very hot drinks can, over time, damage the esophagus and possibly increase cancer risk. Simple changes like enjoying your drinks at a lower temperature and tackling reflux can help to safeguard your long-term health without giving up those drinks you love.