The year that just went by, was obsessed with Ozempic and weight loss. Not just that, but it was also the most searched weight loss drug outpacing Wegovy, its closest competitor, by 300%. As of November 2024, it had a current volume of 16 million searches per month.

What is Ozempic?

Ozempic or semaglutide s a prescribed drug that is used in people with type 2 diabetes. It is given as an injection under your skin and could be prescribed off-label for weight loss. However, the drug is not approved by Food and Drug Administration (FDA) for weight loss.

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The active ingredient in this is semaglutide, which belongs to the class of drugs called glucagon-like peptide-1 or GLP-1 receptor agonists. This is what helps stimulate pancreas to release insulin, prevents, cravings and hunger pangs and prevents increase in blood sugar. It basically mimics the action of naturally produced hormones GLP-1 by activating GLP-1 receptors to achieve these results.

However, it does not come without any side effects. They can include nausea, stomach pain, constipation, thyroid cancer, and more.

But, what if we tell you that you can try these foods which mimic the results of Ozempic, without these above mentioned side effects?

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Filling Foods

These foods are called filling foods, that make you feel full and thus controls your cravings. These are foods high in protein, fiber, and healthy fats which can trigger the release of GLP-1 hormones and other satiety-enhancing effects. Another reason to consider it? These are cheaper than the medications and do not have the unwanted side effects.

Foods that mimic Ozempic effects

Oats: They are rich in soluble fiber called beta-glucan. This can delay gastric emptying and promote feelings of fullness. As per a study published in Current Nutrition Reports, the beta-glucan increases satiety and reduces energy intake by enhancing GLP-1 secretion.

Studies also show that oats can help lower body weigh and harmful LDL- cholesterol levels.

Barley: This also contains beta-glucan, so the effects remain same. Furthermore, the journal Nutrients reported that barley lowered a hunger hormone called leptin.

Legumes, beans, lentils, chickpeas: In one study that included more than 15,000 U.S. adults published in the journal Nutrients found that legume intake was inversely associated with weight gain over the 10-year study period. Adults in the study with moderate to high intakes gained substantially less weight over the past decade than those reporting no legume intake.

Eggs: A study published in Nutrition Research reported that those who had eggs for breakfast reduced overall caloric consumption for the entire day.

Greek Yogurt: It is a healthy, must-have in your diet as it helps you stay fuller longer and also helps with your gut health. Studies suggest that the protein coupled with probiotics enhances satiety and impacts your appetite-regulating hormones to keep your hunger and cravings in check.

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Avocado: They are rich in monounsaturated and polyunsaturated fats, which are considered heart healthy. Avocados are also rich in dietary fiber. A medium-sized avocado has 10 grams of fiber, or more than half the fiber you need in a day. The high fat and fiber content of avocados leads to slower digestion, lower blood sugar and insulin levels and elevates hormones levels that trigger fullness.

Fish: The long-chain omega-3 fatty acids in fish along with the high-quality protein help down-regulate your hunger and appetite.

Nowadays, people of every age group consume junk food. While this junk food is appealing to the taste buds, it can take a toll on liver health. Yes, that’s right. You will be shocked to know that frequent junk food consumption not only leads to obesity, gastric issues, joint pain, and inflammation but also to liver problems. Individuals who consume junk food four to five times a week, combined with a hectic lifestyle, have a higher chance of suffering from fatty liver, which can lead to liver damage. Everyone, including youngsters, should be cautious and prioritise liver health. Ahead of World Liver Day, Dr Chetan Kalal, Assistant Director – Hepatology, Gleneagles Hospital, Parel, spoke about the impact of junk food on liver health.

The junk food crisis

In today’s fast-paced lifestyle, many people rely heavily on junk food due to long working hours, stress, and a lack of time to cook healthy meals. They tend to order food online, consume processed snacks even at work, and skip balanced meals. Many are addicted to junk food, avoid freshly prepared home-cooked meals, and order online at least three to four times a week simply because they enjoy trying a variety of dishes. While ordering food is quick and may seem like a convenient option, such unhealthy eating patterns can negatively impact the liver.

Decoding the link between junk food and liver health, the liver plays a pivotal role in digestion and detoxification. Unfortunately, poor eating habits can overload it, leading to serious liver problems. Junk food is loaded with unhealthy fats, sugar, and refined carbohydrates. When consumed regularly, it leads to the build-up of fat in the liver, a condition known as fatty liver disease. Frequent consumption of junk food can interfere with the liver’s normal functioning. Excess sugar, especially from soft drinks and desserts, is converted into fat and stored in the liver. Similarly, fried and processed foods increase inflammation and make it harder for the liver to process nutrients effectively and function properly.

How does junk food affect the liver?

When the liver is affected, many people experience symptoms such as tiredness, digestive discomfort, bloating, and unexplained weight gain. In many cases, fatty liver may not show clear symptoms in the early stages, making it even more dangerous. If ignored, it can progress to more serious conditions such as liver inflammation, fibrosis, and even cirrhosis, which can permanently damage the liver. If the liver fails to function as it should, the last option may be a transplant. Undergoing a liver transplant can help improve the patient’s quality of life. To avoid the need for a transplant, it is essential to adopt liver-friendly habits.

Recovering from years of liver damage

Adhering to vital measures is the need of the hour to protect liver health. Make sure to avoid junk food, sugary drinks, desserts, bakery items, ice creams, sodas, and colas. Seek guidance from an expert who can advise on healthy eating habits. It is important to include fresh fruits, vegetables, whole grains, nuts, and seeds in the diet to support liver function. Avoid deeply fried snacks, which may be tempting but can lead to health problems. Foods such as samosas, vada, instant noodles, pizza, biscuits, kachori, pakora, puri, potato chips, cakes, white bread, sweets, and buns should be limited or excluded from the diet. Daily physical activity, weight management, and proper hydration are beneficial for liver health. Regular health check-ups, as advised by an expert, can help detect liver problems early and ensure timely treatment.

Trying to lose weight? Drop that wheat bread loaded with carbohydrates, suggests a study, which showed that the humble staple food for people worldwide can cause weight gain even without adding extra calories.

Traditionally, research has focused on high-fat consumption as the main driver of weight gain, but the role of carbohydrate-rich foods such as bread, rice, and noodles—consumed daily around the world—is less explored.

In the study, researchers at Osaka Metropolitan University in Japan studied how carbohydrates influence eating behavior and metabolism in mice.

The researchers examined whether mice preferred foods like wheat, bread, and rice over standard chow, and how these choices affected body weight and energy use.

The animals were divided into several feeding groups, including

• Chow,
• Chow + Bread,
• Chow + Wheat flour,
• Chow + Rice flour,
• High-fat diet (HFD) + Chow,
• HFD + Wheat flour.

Mice that consumed rice flour similarly gained weight to those that ate wheat flour. In contrast, mice given a High-fat diet (HFD) + Wheat flour gained less weight than those on a High-fat diet (HFD) + Chow.

"These findings suggest that weight gain may not be due to wheat-specific effects, but rather to a strong preference for carbohydrates and the associated metabolic changes," said Professor Shigenobu Matsumura from the varsity’s Graduate School of Human Life and Ecology.

What Is Driving Weight Gain

The results showed that weight gain was not caused by "overeating," but by a reduction in energy expenditure.

Further analysis revealed higher levels of fatty acids in the blood and lower levels of essential amino acids. In the liver, fat accumulation increased, along with the activity of genes linked to fatty acid production and lipid transport.

When wheat flour was removed from the diet, both body weight and metabolic abnormalities improved quickly. This suggests that moving away from a wheat-heavy diet and toward a more balanced one may help regulate body weight more effectively.

While the study was conducted in mice, the researchers aim to focus on humans “to verify the extent to which the metabolic changes identified in this study apply to actual dietary habits".

"We also intend to investigate how factors such as whole grains, unrefined grains, and foods rich in dietary fiber, as well as their combinations with proteins and fats, food processing methods, and timing of consumption, affect metabolic responses to carbohydrate intake. In the future, we hope this will serve as a scientific foundation for achieving a balance between "taste" and "health" in the fields of nutritional guidance, food education, and food development," stated Professor Matsumura.

Oats for breakfast are a go-to choice for many health enthusiasts. Celebrities often turn to this source of complex carbohydrates to kick-start their day—but research suggests some health benefits of this breakfast food that are often overlooked. According to a study by the University of Bonn, eating oats for just two days can help reduce cholesterol levels naturally, and the benefits can last for weeks afterwards. The study, published in the Nature Communications journal, found that even short-term dietary changes can contribute to improvements in people’s risk of metabolic diseases. Experts say that such studies reinforce the importance of following a healthy diet for heart health.

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What makes oats a healthy breakfast choice?

Oats are rich in soluble fibre and beta-glucans, and these nutrients make them good for cholesterol management and heart health. Experts say that while two days of oats can benefit the heart, it is important to follow a long-term dietary regime to maximise the benefits. Researchers noted that oats can improve cholesterol management by altering the gut microbiome. They help produce compounds that boost metabolism, such as ferulic acid. At the same time, oats help reduce insulin resistance, which is a driving factor for diabetes.

How do oats improve heart health?

In the trial, participants who were suffering from metabolic syndrome followed an oat-based diet for two days—about 300 mg per day. This was divided into three meals along with portions of fruits and vegetables. The results were:

1. Weight loss of 2 kilos
2. LDL dropped by 10 per cent
3. Benefits sustained after six weeks
4. Blood pressure also improved

A control group also followed a calorie-restricted diet, and the improvements noted were greater compared to people who consumed oats.

Are two days sufficient to reap the benefits of oats?

The study found that a high-intensity oat diet had stronger effects compared to a longer and moderate intake. It was found that people who ate 80 grams of oats for six weeks showed minor improvements compared to those who followed the strict two-day plan. This suggests that a structured dietary intervention, even if short, can deliver faster metabolic results.

Nutrition in oats

Oats contain some protein but are primarily rich in soluble fibre, beta-glucans, and complex carbohydrates. One cup of oats can provide about 4–6 grams of fibre. To enhance the nutritional value and benefits of oats, you can also add fruits and vegetables.

Conclusively, it can be said that diet can have a strong impact on heart health, especially if one makes informed choices. However, experts warn against relying on short-term solutions for long-term care. Particularly in the case of patients with high cholesterol, consulting an expert is important before making dietary changes. While eating oats for just two days can be beneficial, it is advisable to follow a long-term plan to improve overall metabolic health.