The year that just went by, was obsessed with Ozempic and weight loss. Not just that, but it was also the most searched weight loss drug outpacing Wegovy, its closest competitor, by 300%. As of November 2024, it had a current volume of 16 million searches per month.

What is Ozempic?

Ozempic or semaglutide s a prescribed drug that is used in people with type 2 diabetes. It is given as an injection under your skin and could be prescribed off-label for weight loss. However, the drug is not approved by Food and Drug Administration (FDA) for weight loss.

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The active ingredient in this is semaglutide, which belongs to the class of drugs called glucagon-like peptide-1 or GLP-1 receptor agonists. This is what helps stimulate pancreas to release insulin, prevents, cravings and hunger pangs and prevents increase in blood sugar. It basically mimics the action of naturally produced hormones GLP-1 by activating GLP-1 receptors to achieve these results.

However, it does not come without any side effects. They can include nausea, stomach pain, constipation, thyroid cancer, and more.

But, what if we tell you that you can try these foods which mimic the results of Ozempic, without these above mentioned side effects?

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Filling Foods

These foods are called filling foods, that make you feel full and thus controls your cravings. These are foods high in protein, fiber, and healthy fats which can trigger the release of GLP-1 hormones and other satiety-enhancing effects. Another reason to consider it? These are cheaper than the medications and do not have the unwanted side effects.

Foods that mimic Ozempic effects

Oats: They are rich in soluble fiber called beta-glucan. This can delay gastric emptying and promote feelings of fullness. As per a study published in Current Nutrition Reports, the beta-glucan increases satiety and reduces energy intake by enhancing GLP-1 secretion.

Studies also show that oats can help lower body weigh and harmful LDL- cholesterol levels.

Barley: This also contains beta-glucan, so the effects remain same. Furthermore, the journal Nutrients reported that barley lowered a hunger hormone called leptin.

Legumes, beans, lentils, chickpeas: In one study that included more than 15,000 U.S. adults published in the journal Nutrients found that legume intake was inversely associated with weight gain over the 10-year study period. Adults in the study with moderate to high intakes gained substantially less weight over the past decade than those reporting no legume intake.

Eggs: A study published in Nutrition Research reported that those who had eggs for breakfast reduced overall caloric consumption for the entire day.

Greek Yogurt: It is a healthy, must-have in your diet as it helps you stay fuller longer and also helps with your gut health. Studies suggest that the protein coupled with probiotics enhances satiety and impacts your appetite-regulating hormones to keep your hunger and cravings in check.

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Avocado: They are rich in monounsaturated and polyunsaturated fats, which are considered heart healthy. Avocados are also rich in dietary fiber. A medium-sized avocado has 10 grams of fiber, or more than half the fiber you need in a day. The high fat and fiber content of avocados leads to slower digestion, lower blood sugar and insulin levels and elevates hormones levels that trigger fullness.

Fish: The long-chain omega-3 fatty acids in fish along with the high-quality protein help down-regulate your hunger and appetite.

The latest Annual Ground Water Quality Report 2025 by the Central Ground Water Board (CGWB) has delivered a worrying revelation: Punjab now records the highest intensity of uranium contamination ever reported in India, with 62.5% of groundwater samples exceeding the safe limit post-monsoon. This is followed by Haryana, Delhi, Karnataka and Uttar Pradesh, indicating a dangerous pattern across north and north-central India.

While nitrate and fluoride remain more widespread contaminants, uranium’s increasing presence raises an urgent public health concern because even low-dose, long-term exposure can quietly harm vital organs.

Where Is Uranium Contamination Rising?

The CGWB tested 3,754 groundwater samples across India in pre- and post-monsoon seasons. The findings show a clear upward trend:

Nationally, uranium exceedance rose from 6.71% (pre-monsoon) to 7.91% (post-monsoon).

Punjab recorded the highest contamination:

• 53.04% pre-monsoon
• 62.50% post-monsoon

Haryana followed with 15–23.75% of samples above limits.

• Delhi: 13–15.66%
• Karnataka: 6–8%
• Uttar Pradesh: 5–6%

The report highlights northwestern India: Punjab, Haryana, Delhi, and parts of Rajasthan and Uttar Pradesh — as the main hotspot, likely due to geogenic factors, aquifer depletion, and intense groundwater extraction. Meanwhile, eastern and southern states reported minimal contamination.

Why Uranium in Water Is Dangerous

According to the 2025 study “Uranium’s hazardous effects on humans and recent developments in treatment,” the real threat from uranium lies in its chemical toxicity, not its radioactivity.

Kidney Damage: The Most Significant Risk

Uranium behaves like a heavy metal that gets absorbed and stored in the kidneys, impairing their ability to filter waste.

This can lead to:

• Proteinuria (excess protein in urine)
• Reduced kidney function
• Long-term kidney diseases

Even low-dose, chronic exposure through drinking water can gradually weaken renal functioning.

Respiratory Harm and Lung Cancer Risk

People who inhale uranium particles — especially workers in mining or processing — face:

• Chronic respiratory irritation
• Persistent coughing
• Higher risk of lung cancer, particularly due to radon gas produced as uranium decays

Gastrointestinal Entry and Toxic Build-Up

Recent findings note that the gastrointestinal system is the main route of uranium entry. Once consumed through contaminated water, uranium moves from the stomach and intestines into soft tissues and organs.

Bone Accumulation and Cancer Risk

Because uranium is a chemical analog of calcium, it can get deposited into bones. Over time, this raises the risk of bone cancer and may interfere with normal bone cell functioning.

Possible Reproductive and Developmental Effects

Animal studies suggest:

• Potential risks of congenital disabilities
• Effects on reproductive organs
• But direct evidence in humans remains incomplete, calling for more research.

Neurological and Immune Effects Being Explored

Some studies hint at:

• Behavioral changes
• Cognitive deficits
• Unclear impacts on the immune system

These areas remain under-studied but concerning.

Why India Must Worry Now

The CGWB report warns that while most groundwater in India remains safe, the pockets of rising uranium contamination require immediate monitoring and mitigation. With millions relying on groundwater for daily consumption, even a small rise in toxic metals can translate into widespread health damage over time.

Long-term exposure rarely shows immediate symptoms, which makes the threat quiet but deeply harmful.

A new study suggests that drinking coffee could help certain individuals slow their biological ageing. Researchers found that consuming up to four cups a day may give some people a biological advantage, effectively making their cells appear five years younger than those who abstain. The study, published in BMJ Mental Health, focused on people with severe mental illnesses, including schizophrenia, bipolar disorder, and psychosis.

How Coffee Might Affect Ageing

The scientists linked this effect to coffee’s high antioxidant content, which appears to protect and lengthen telomeres—the protective caps at the ends of chromosomes. Telomeres function like the plastic tips on shoelaces, preventing chromosomes from fraying. Normally, telomeres shorten naturally as we age, but in people with major psychiatric conditions, this process is often accelerated, contributing to premature cellular ageing.

According to News Medical, coffee’s antioxidants can reduce oxidative stress, a factor that speeds up telomere shortening and biological ageing. By consuming the optimal amount, individuals may slow this process, potentially gaining the equivalent of five years of cellular youth.

The Study: Coffee, Mental Health, and Telomeres

The study observed 436 adults, including 259 participants with schizophrenia and the remainder with affective disorders like bipolar disorder or major depressive disorder with psychotic features. Researchers analyzed participants’ coffee consumption and its impact on telomere length.

Results showed that drinking up to four cups daily was associated with longer telomeres. However, consuming more than five cups each day did not provide additional benefits; in fact, heavy coffee drinkers were biologically older compared to those consuming one or two cups. This highlights the importance of moderation, as excessive caffeine intake may lead to cellular stress and telomere shortening.

The study authors emphasized that while this research cannot definitively prove causation—because it was observational—coffee’s established health benefits make it a plausible contributor to preserving cellular health. As they noted: “Telomeres are highly sensitive to both oxidative stress and inflammation, further highlighting how coffee intake could help maintain cellular integrity in a population predisposed to accelerated ageing.”

Guidelines and Considerations

Global health authorities generally recommend limiting caffeine intake to around 400 mg per day, roughly equivalent to four cups of coffee. Staying within this range seems to provide the protective effects without overloading the body.

The researchers also acknowledged some limitations in the study. They did not track other sources of caffeine participants may have consumed, nor did they account for the type of coffee or the time of day it was consumed, factors that could influence outcomes.

Overall, the study reinforces the idea that moderate coffee consumption can be a simple lifestyle choice with potential long-term benefits for mental health populations and, possibly, the general population as well.

Americans reach for coffee more often than any other drink, and studies continue to show that a couple of daily cups suit most people and may even support overall health. At the same time, nearly half of U.S. adults live with high blood pressure, defined as a systolic reading above 130 mmHg or a diastolic reading above 80 mmHg.

This raises a natural question. Does caffeine play a part in rising blood pressure levels? Is our strong preference for coffee adding to the problem, or could regular coffee intake possibly help keep blood pressure lower?

Coffee And High Blood Pressure: Is There A Link?

Many people enjoy coffee because it sharpens focus and lifts energy. That same stimulating action is also what can nudge blood pressure upward for a short while. John Higgins, MD, a cardiologist and professor of medicine at UTHealth Houston, agrees that this happens and notes that the general answer is yes. Moderate coffee use is usually acceptable for people whose blood pressure is stable or only slightly raised, though individuals react differently. While caffeine can push readings higher for a brief period, long-term drinking patterns tell another story.

Several studies report no added risk of hypertension among people who drink coffee often. A review of 13 cohort studies found no clear link between coffee intake and the development of high blood pressure. A separate 2023 review even noted that heavier coffee consumption was tied to a 7 percent lower risk of hypertension. The evidence suggests that people who drink coffee regularly tend to build tolerance to caffeine’s short-lived effect on blood pressure.

The 2025 AHA/ACC Hypertension Guideline does not list specific limits for coffee, and the American Heart Association states that moderate amounts appear fine for healthy adults.

How Much Coffee Is Safe To Consume For Blood Pressure Patients?

There is no set rule, but research supports one to three cups a day for most people whose blood pressure is well controlled.

Remember that caffeine levels can vary quite a bit depending on the brewing method, and it is wise to think about your total caffeine intake, including tea, soft drinks, and energy drinks.

Keep the following points in mind when having coffee:

• Choose your add-ins carefully. Sugar, flavored syrups, and full-fat milk can lead to weight gain and metabolic issues, both of which raise blood pressure risk and may add to caffeine’s influence.
• Avoid drinking coffee late in the afternoon. Coffee taken after two or three o’clock can disturb sleep, and poor sleep on its own can worsen blood pressure.
• Allow some time before checking your blood pressure. Coffee can cause a temporary rise, giving you an inaccurate reading. If you want to see how caffeine affects you, measure your pressure before drinking and again 30 to 60 minutes later.

Who Should Avoid Drinking Coffee?

Drinking coffee is generally safe for those with steady or slightly raised blood pressure, and the greater concern usually lies with uncontrolled hypertension. Still, people who are sensitive to caffeine or have poorly managed blood pressure should be more careful.

Extra caution is advised if you have:

• Uncontrolled stage 2 or 3 hypertension
• Organ damage tied to long-standing high blood pressure or other chronic illnesses
• Heart rhythm problems, particularly atrial fibrillation
• Conditions such as hypertrophic cardiomyopathy

In these situations, consider limiting or avoiding caffeinated coffee until your readings improve. Keep in mind that coffee is only one part of overall blood pressure care. Do not overlook reducing sodium intake, staying active, managing weight, and following prescribed treatment.