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Who does not enjoy staying young? Especially when you can do it with just tweaking your diet a little! A recent study published in Nature Publishing Group Aging, reveals that a nutrient-rich diet, similar to the Mediterranean style plays an important role in slowing brain aging.
The study used blood biomarker analysis, brain imaging and cognitive assessments to conclude that specific nutrients like fatty acids, antioxidants, carotenoids, vitamin E, and choline, are essential to support healthy brain function and delay cognitive decline.
This was a cross-sectional study which involved 100 adults between the ages of 65 and 75. The participants were healthy and showed no evidence of cognitive impairment and they underwent several tests, including MRIs, mental tests and blood work. The researchers studied 139 variables of brain health, including brain metabolism, function, and structure.
ALSO READ: Longevity Diets: What to Eat to Live Past 100
Fatty Acids: Vaccenic, gondoic, alpha-linolenic, eicosapentaenoic, eicosadienoic, and lignoceric acids, commonly found in plants, dairy, and oily fish, contribute to neuron maintenance.
Antioxidants and Carotenoids: Cis-lutein, trans-lutein, and zeaxanthin are essential for neutralizing free radicals and protecting the brain from oxidative stress.
Vitamin E: This antioxidant helps safeguard brain cells, with research suggesting its role in preventing dementias like Alzheimer's disease.
Choline: A vital nutrient for the neurotransmitter acetylcholine, which is important for memory and attention.
Experts affirm that these nutrients (mentioned above) are commonly found in the Mediterranean diet and are known for their neuroprotective properties. The Mediterranean diet has positive effects on brain, and there is enough evidence to prove that too. It is because the fatty acids maintain neurons, while the antioxidants combat oxidative stress, which then preserves brain function.
Choline, which is found in egg yolks are also essential for acetylcholine production, which supports cognitive functions such as memory and focus. There are certain nutrients which one can find in egg yolks that reduce oxidative stress and inflammation. Further, they also support cell membrane integrity and improve brain blood flow, which in turn enhances neuroplasticity. These are all crucial for healthy aging.
ALSO READ: What Is The Green Mediterranean Diet?
There are also additional benefits too, for instance, omega-3 fatty acids also reduce heart disease risks, whereas antioxidants like vitamin C and E also boost immune system. The Mediterranean diet in all, also manages arthritis and metabolic syndrome.
Fatty Fish: These include Salmon, mackerel, sardines, and trout are rich in omega-3s.
Leafy Greens: These include spinach, kale, broccoli. These are packed with carotenoids like lutein and zeaxanthin.
Nuts and Seeds: They are rich in alpha-linolenic acid (ALA) and vitamin E. You can include almonds, sunflower seeds, and flaxseeds in your diet.
Eggs and Liver: They are a great source of choline, which can be helpful for brain function.
Colorful vegetables and fruits: Peppers, tomatoes, and oranges are rich in anti-oxidants and vitamin C.
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Your gut's petrol maybe running low and it is causing you all sorts of gut issues. But, what does it really mean?
Bloating that doesn’t settle, gas that feels unpredictable, sluggish digestion, and a constant sense that your gut just isn’t cooperating anymore. All of these complaints are becoming increasingly common, especially in urban India. While many people blame stress or food intolerances, experts say the issue may lie deeper, at the level of the gut microbiome. One key reason: falling levels of butyrate, a small but powerful compound essential for gut health.
Often described as the gut’s “petrol,” butyrate plays a critical role in keeping the digestive system resilient and balanced.
Butyrate is a short-chain fatty acid (SCFA) produced when beneficial gut bacteria ferment dietary fiber. Think of it as the primary fuel source for the cells lining the colon. When enough butyrate is present, the gut lining stays strong, inflammation remains under control, and digestion functions smoothly.
When levels drop, the gut barrier weakens. This can lead to inflammation, slower digestion, immune imbalance, and even disruptions in metabolism and mood. In simple terms, low butyrate means the gut struggles to repair and protect itself.
Recent gut microbiome analyses suggest that butyrate levels are declining sharply, particularly among adults living in metro cities. The drop isn’t limited to older age groups, even people in their 20s and 30s are showing early signs of imbalance.
While other SCFAs like propionate and acetate may remain relatively stable, butyrate appears to be the first to fall. This imbalance is increasingly being linked to rising cases of irritable bowel symptoms, unexplained digestive discomfort, and metabolic issues, even when routine tests appear normal.
Low butyrate usually signals one of two problems, or both. Either the butyrate-producing bacteria are disappearing, or the diet lacks the fibers those bacteria depend on. Many people believe they eat “healthy,” yet still miss out on fiber diversity.
Without adequate fuel, beneficial bacteria struggle to survive. As a result, the gut ecosystem shifts, leading to symptoms such as bloating, cramps, urgency, alternating constipation and loose stools, fatigue, brain fog, and sugar cravings. These issues often go undetected because structural tests show no obvious damage.
Traditional Indian diets once provided a wide range of fibers through millets, dals, vegetables, fermented foods, and seasonal produce. Over time, these have been replaced by ultra-processed foods that are low in fiber and high in sugar and refined carbohydrates.
Add irregular meal timings, chronic stress, poor sleep, frequent antibiotic or painkiller use, and environmental pollution, and the gut microbiome takes a hit. The bacteria that produce butyrate simply fade away, much like shutting down a factory that no longer receives raw materials.
Restoring butyrate isn’t about quick fixes. Supplements may provide temporary relief, but they don’t rebuild the ecosystem. The foundation is dietary diversity.
Foods that help feed butyrate-producing bacteria include millets, legumes, whole grains, fruits, vegetables, seeds, and resistant starches. Everyday foods such as bananas, onions, garlic, oats, and cooked-and-cooled rice act as natural prebiotics. Fermented foods like curd and buttermilk also support microbial balance.
With consistent changes, the gut can slowly restart its butyrate production, though meaningful recovery may take several months.
Low butyrate isn’t just a digestive issue. It reflects how modern lifestyles are reshaping gut health at a population level. Improving fiber diversity could strengthen immunity, metabolism, and long-term health more effectively than treating symptoms later.
In many ways, restoring butyrate means returning to simpler, whole-food eating habits — and giving the gut the fuel it was designed to run on.
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Millions of people are stocking up on food for Christmas, planning the main meal and everything that comes with the festive stretch. What many do not realise is that there is a proven link between cancer and one much-loved item that often sits on the Christmas Day plate.
While sugar is often blamed for causing cancer, that belief is not supported by evidence. In fact, only two foods have a confirmed, direct link to cancer: alcohol and processed meat. And popular pigs in blankets clearly fall into the processed meat category.
To be clear, no one is saying that eating pigs in blankets on Christmas Day will give you cancer, just as no one suggests that a single glass of wine or sherry will lead to a diagnosis. That said, recent scientific evidence shows there is no truly safe level of alcohol consumption. In a recent report, Vivek Murthy, former surgeon general of the US Public Health Service, warned that alcohol use has been directly linked to at least seven different types of cancer, and that even light or moderate drinking can raise a person’s cancer risk.
As per Mirror, both processed meat and alcohol are classified as Group 1 carcinogens by the World Health Organisation, which means there is clear evidence they can cause cancer in humans. According to the WHO, “There is convincing evidence that the agent causes cancer.” Tobacco smoking and asbestos are also listed as Group 1 carcinogens, although the organisation clarifies that this does not mean alcohol and processed meat are as dangerous as smoking or asbestos.
Cancer Research UK also states clearly, “We know for certain that processed meat causes cancer. We are as confident about this link as we are about other established causes of cancer, such as tobacco and alcohol.”
Cancer Research UK explains that processed meats contain chemicals that are either added during processing or formed during cooking. These include nitrates and nitrites, which help keep processed meat fresh for longer. The organisation notes, “When we consume them, nitrates and nitrites can turn into N-nitroso chemicals (NOCs), which can damage the cells lining the bowel. This damage can increase the risk of bowel cancer.”
Alcohol increases cancer risk through biological processes that occur as it is broken down in the body. This means that any alcoholic drink, regardless of how expensive, high-quality, or mild it may seem, carries a cancer risk. There is no safe threshold for drinking alcohol. The WHO says cancer risk “rises significantly the more alcohol is consumed,” but also points out that “the latest available data show that around half of all alcohol-related cancers are caused by ‘light’ and ‘moderate’ drinking,” defined as less than 1.5 litres of wine, less than 3.5 litres of beer, or under 450 millilitres of spirits per week.
In 2021, researchers at Oxford University reported that the “largest review of all large-scale studies to date shows red and processed meat increase the risk of heart disease.”
Worldwide, coronary heart disease causes nearly nine million deaths each year, making it the leading cause of death globally. Scientists from the University of Oxford’s Nuffield Department of Population Health said their analysis “showed that each additional 50g per day of processed meat, such as bacon, ham, or sausages, was linked to an 18% higher risk of coronary heart disease.”
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Eating is something we do every day, and its connection to our weight is undeniable. Most of us concentrate on what we eat, and rightly so, because the nutritional value and calorie content of food directly impact our weight. Yet, an increasingly important factor in weight management is when we eat. Nutritionist Pooja Makhija explains the science behind having early dinners, particularly in the evening, and how this aligns with the body clock to support overall weight management.
In an Instagram video, she writes in the caption, “You don't start digesting worse at night because of the food… you digest worse because melatonin has already risen,” adding, “Melatonin climbs 2–3 hours before your bedtime, dropping your insulin sensitivity by up to 50% and switching fat cells into storage mode. So the same meal hits very differently at 7 pm vs 10 pm.”
Melatonin is a hormone made by the pineal gland in the brain that helps control the body’s sleep-wake cycle. Its levels usually rise in the evening, peak during the night, and fall in the early morning. Many doctors even recommend melatonin supplements to help regulate sleep patterns, though they can sometimes cause side effects, so consulting a physician is advised, as per Healthline.
In her video, Pooja grabs attention by asking, “We all know that melatonin makes you sleepy. But what if I told you that melatonin wakes up your fat cells and makes them store more? Hadn't heard of that?”
She continues, “Melatonin isn’t just your sleep hormone. It’s your body’s night mode switch. As it rises in the evening, your metabolism slows down. Insulin sensitivity drops 25 to 50 percent, glucose clearance slows, and your fat cells switch from burning energy to storing it.” Referring to a study published in the *Clinical Endocrinology and Metabolism* journal, she adds, “People who ate dinner when their melatonin was high had a 34 percent higher glucose spike. Same people, same meal, same calories—just bad timing.”
Front-loading calories is a way of eating where most of your daily calories are consumed earlier in the day, with a big breakfast and hearty lunch and a lighter dinner in the evening. This approach matches your meals with your body’s natural circadian rhythms, improving metabolism, insulin response, and appetite control. It helps with weight management and energy levels by taking advantage of the morning metabolism, reducing late-night cravings, and supporting better sleep.
Pooja Makhija says the most effective method to prevent melatonin from triggering fat storage is to eat early dinners and front-load calories during the day.
“So when most of your calories land late at night, it’s at a time when your biology is saying, ‘I’m done for the day; I’m not burning more.’ In contrast, front-loading calories with a big breakfast, solid lunch, and small dinner means you’re eating when melatonin is low. Your insulin is sharp, mitochondria are active, and your body is in daytime burning mode,” she explains.
She concludes with a reminder: “Your fat cells have melatonin receptors, and they behave differently depending on the time of day. Front-loading isn’t a hack—it’s circadian biology. Melatonin guides your metabolism. So eat in tune with your body clock, not against it, and notice the difference.”
According to Healthline, the ideal dinner time for better melatonin regulation and metabolism is 2–3 hours before bedtime—before your body naturally begins releasing melatonin—to avoid insulin spikes and fat storage.
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