Who does not enjoy staying young? Especially when you can do it with just tweaking your diet a little! A recent study published in Nature Publishing Group Aging, reveals that a nutrient-rich diet, similar to the Mediterranean style plays an important role in slowing brain aging.

The study used blood biomarker analysis, brain imaging and cognitive assessments to conclude that specific nutrients like fatty acids, antioxidants, carotenoids, vitamin E, and choline, are essential to support healthy brain function and delay cognitive decline.

How Was The Study Conducted?

This was a cross-sectional study which involved 100 adults between the ages of 65 and 75. The participants were healthy and showed no evidence of cognitive impairment and they underwent several tests, including MRIs, mental tests and blood work. The researchers studied 139 variables of brain health, including brain metabolism, function, and structure.

ALSO READ: Longevity Diets: What to Eat to Live Past 100

Nutrients The Protect The Brain

Fatty Acids: Vaccenic, gondoic, alpha-linolenic, eicosapentaenoic, eicosadienoic, and lignoceric acids, commonly found in plants, dairy, and oily fish, contribute to neuron maintenance.

Antioxidants and Carotenoids: Cis-lutein, trans-lutein, and zeaxanthin are essential for neutralizing free radicals and protecting the brain from oxidative stress.

Vitamin E: This antioxidant helps safeguard brain cells, with research suggesting its role in preventing dementias like Alzheimer's disease.

Choline: A vital nutrient for the neurotransmitter acetylcholine, which is important for memory and attention.

The Science Behind Mediterranean Diet and Brain Health

Experts affirm that these nutrients (mentioned above) are commonly found in the Mediterranean diet and are known for their neuroprotective properties. The Mediterranean diet has positive effects on brain, and there is enough evidence to prove that too. It is because the fatty acids maintain neurons, while the antioxidants combat oxidative stress, which then preserves brain function.

Choline, which is found in egg yolks are also essential for acetylcholine production, which supports cognitive functions such as memory and focus. There are certain nutrients which one can find in egg yolks that reduce oxidative stress and inflammation. Further, they also support cell membrane integrity and improve brain blood flow, which in turn enhances neuroplasticity. These are all crucial for healthy aging.

ALSO READ: What Is The Green Mediterranean Diet?

There are also additional benefits too, for instance, omega-3 fatty acids also reduce heart disease risks, whereas antioxidants like vitamin C and E also boost immune system. The Mediterranean diet in all, also manages arthritis and metabolic syndrome.

Ingredients You Can In Your Diet To Boost Brain Health

Fatty Fish: These include Salmon, mackerel, sardines, and trout are rich in omega-3s.

Leafy Greens: These include spinach, kale, broccoli. These are packed with carotenoids like lutein and zeaxanthin.

Nuts and Seeds: They are rich in alpha-linolenic acid (ALA) and vitamin E. You can include almonds, sunflower seeds, and flaxseeds in your diet.

Eggs and Liver: They are a great source of choline, which can be helpful for brain function.

Colorful vegetables and fruits: Peppers, tomatoes, and oranges are rich in anti-oxidants and vitamin C.

It’s 3 pm. Are you feeling the familiar feeling of slow down with heavy eyelids, fading concentration and a sudden urge for coffee? While you may blame a busy schedule, long screen time or poor sleep for the afternoon slump, your nutrition levels may also play a role in how well you sustain your energy, experts said.

With increasing work stress and responsibilities, your body requires a steady supply of nutrients for energy production, brain support and normal body functioning. However, afternoon tiredness is not always a sign of nutrient deficiency. Sleep quality, stress, physical activity, hydration and even the natural dip in alertness that occurs during the day can influence energy levels.

Yet, nutrition can affect how well you sustain your energy through the day.

Could Your Lunch Be Making You Tired?

Speaking to HealthandMe, Meenakshi Aggarwal, Clinical Dietician, MAIINS, Marengo Asia Hospitals, Gurugram, said that a lunch built largely around refined carbohydrates or sugary foods, with little protein or fibre, may leave you feeling hungry again sooner.

“Choosing whole grains, pulses, vegetables, curd, eggs or other protein-rich foods can make a meal more balanced and support steadier energy,” she said.

The Nutrients That Matter

Before reaching for another cup of coffee, look at your plate. Iron deserves special attention. It is essential for hemoglobin formation and oxygen transport, as well as normal cellular energy metabolism. Research has found that people with iron deficiency can experience fatigue even without anemia.

“Iron is needed to make hemoglobin, the protein that carries oxygen around the blood. Fatigue, weakness, poor concentration, and reduced stamina are all symptoms of low iron levels. Lentils, beans, leafy greens, eggs and meat are iron-rich foods,” Shabana Parveen, Head, Nutrition & Dietetics, Artemis Hospitals, told HealthandMe.

Other nutrients, including vitamin B12, folate and magnesium, also have important roles in normal blood formation, nervous-system function and energy metabolism.

Vitamin B12 helps make red blood cells and keeps nerves healthy. Tiredness, weakness and concentration problems may be related to inadequate intake or poor absorption. Common sources include dairy products, eggs, fish and meat.

Magnesium participates in hundreds of processes in the body, including energy production and muscle function. Nuts, seeds, whole grains, legumes and leafy vegetables can help supply it.

When Fatigue Needs More Than A Diet Fix

The experts noted that fatigue alone does not prove a deficiency. Dehydration, irregular meals, too much caffeine, lack of sleep, stress, thyroid problems, anemia and other health conditions can also play a part, Parveen said.

Instead of reaching for another sugary snack or coffee, it is better to focus on balanced meals containing protein, whole grains, vegetables, fruits and healthy fats.

If tiredness is common, severe or persistent despite a healthy lifestyle, speak to a healthcare professional to identify the underlying cause.

A balanced lunch, adequate fluids and sufficient sleep may be more useful than simply pushing through the slump.

Why Nutrition Matters Beyond Energy

The importance of nutrition, however, goes beyond managing an afternoon energy slump.

Dr Sabine Kapasi, Global Health Strategist and a UN Advisor, told HealthandMe that preventive healthcare has traditionally centered on screening, exercise and early diagnosis.

Nutrition often receives less attention, despite being one of the strongest modifiable factors influencing long-term health.

“Nutrition matters because it affects several metabolic pathways at the same time. Weight, blood pressure, blood glucose and cholesterol are closely linked to diet and are major risk factors for cardiovascular disease, diabetes and other NCDs.”

Ever wondered why a food you have eaten comfortably for years suddenly starts causing bloating, abdominal discomfort or bowel changes? The food may not have changed — your gut may have.

Food intolerance can develop in adulthood as the gut microbiome, digestive enzymes, intestinal lining and gut-brain interactions change with age, illness, medications, diet, stress and other factors.

What Changes Inside The Gut?

“The intestine is a dynamic ecosystem. Its microbiome, immune system, intestinal lining and digestive enzymes are constantly changing and adapting to factors such as age, infections, antibiotics, medications, diet, stress and hormonal changes,” Dr. Amit Maydeo, Chairman, Institute of Gastrosciences, Sir HN Reliance Foundation Hospital, told HealthandMe.

Dr. Geeta Malkan-Billa, Director of Gastroenterology & Hepatology, Dr. L. H. Hiranandani Hospital, highlighted several changes that can affect food tolerance:

• Digestive enzymes: Lactase levels decline after childhood. For some, lactose intolerance can appear in their 20s–40s. Diamine oxidase, which helps break down histamine, can also decrease.
• Gut microbiome: Antibiotics, infections, illness and major diet changes can alter gut bacteria, changing how foods are fermented and potentially causing more gas or bloating.
• Past infections: Gastroenteritis can affect the gut lining, digestive enzymes and gut nerves for months, making certain foods harder to tolerate.
• Gut lining: NSAIDs, tobacco, heavy alcohol use and chronic stress can increase intestinal permeability and trigger low-grade immune activity.
• Gut movement: Ageing, surgery, diabetes, thyroid problems and GLP-1 medications can alter how quickly food moves through the gut, affecting fermentation and potentially contributing to bacterial overgrowth.

Why Does A Familiar Food Suddenly Cause Problems?

Dr Amit said that changes in gut bacteria can alter how carbohydrates and fibers are fermented, while a more sensitive gut lining can make previously tolerated foods feel uncomfortable.

A previous gut infection can also leave the gut more sensitive. After gastroenteritis, some people develop post-infectious IBS, which can make certain foods trigger symptoms.

Stress can further amplify these sensations through the gut-brain axis. As the nervous system becomes more sensitive, normal amounts of gas or intestinal distension may feel uncomfortable, Dr. Amit said.

It May Not Be Food Intolerance

Not every reaction to food is an intolerance. Some conditions can look similar but are actually different:

• Celiac disease: An autoimmune condition that can develop at any age, rather than simply an inability to digest gluten or wheat.
• Food allergy: True IgE-mediated food allergies can also develop during adulthood.

So, a new reaction to a familiar food should not automatically be labelled as food intolerance.

What Should You Do?

Before cutting gluten from your diet, get celiac serology testing, as going gluten-free beforehand can affect the results.

A two-week food and symptom diary can also help identify patterns. Note:

• What you ate
• How much you ate
• When symptoms appeared

The key is to remember that the food itself may not have suddenly become “bad” for you. Your gut’s ability to process and tolerate it may have changed.

Sometimes, however, a new food allergy or another gastrointestinal disorder may need to be ruled out.

When Should You See A Doctor?

Certain symptoms should not simply be blamed on food intolerance. See a doctor if you experience:

• Unexplained weight loss
• Blood in the stool
• Anaemia
• Symptoms that wake you at night
• Swelling
• Difficulty breathing

These symptoms need medical evaluation rather than simply eliminating foods from your diet.

Sorbitol is often seen as a healthier alternative to sugar. The sugar alcohol is widely used in sugar-free chewing gum, candies and other low-calorie foods, offering sweetness with fewer calories than regular sugar.

But new research suggests that sorbitol may not just pass through the digestive system as it was previously assumed.

Scientists have found that after reaching the liver, sorbitol may be converted into a compound related to fructose, where it could trigger metabolic changes associated with fatty liver disease.

How Sorbitol Interacts With The Body?

Researchers from Washington University in St. Louis used zebrafish models to analyse what happens to sorbitol after it enters the body.

They found that after eating a meal, sorbitol can be produced naturally in the intestine from the glucose. What happens next depends partly on the bacteria residing in the gut.

Certain bacteria, including Aeromonas strains that degrades sorbitol, can consume sorbitol and convert it into a harmless bacterial byproduct. This may act as a protective filter, preventing the compound from reaching the liver.

But when those bacteria are absent, more sorbitol may pass through to the liver. Researchers found sorbitol can be converted into a derivative of fructose.

The researchers describe sorbitol as being “one transformation away from fructose”, because of how closely the two compounds are connected through metabolism.

Also read: Should You Really Cut Out Rice And Roti To Lose Weight? Expert Explains The Truth About Carbs

Could Sorbitol Affect Liver Health?

The metabolism of fructose in the liver has been linked to steatotic liver disease, a condition in which excess fat accumulates in liver cells. The new findings suggest that sorbitol may have some of the same metabolic effects.

The researchers found that sorbitol could contribute to processes linked with liver fat accumulation when the gut's ability to break it down was impaired.

However, this does not mean that eating sugar-free gum or food containing sorbitol will automatically and mandatorily cause fatty liver disease.

The research was conducted in zebrafish, and the study is exploring a biological mechanism rather than demonstrating that ordinary dietary sorbitol causes liver disease in humans.

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Gut Bacteria May Make A Difference

One of the more unexpected findings was the potential role of the gut microbiome in preventing this scenario. At relatively low levels, including amounts naturally obtained from fruit, researchers found that bacteria appeared capable of breaking down sorbitol.

Problems may surface when the amount of sorbitol becomes too high for these microbes to process efficiently. That could happen through consuming large quantities of products that contain sorbitol. High glucose intake may also increase the amount of sorbitol produced inside the intestine.

The researchers therefore suggest that how much sorbitol is consumed and the composition of an individual's gut bacteria could influence what happens to the compound and thus shape the risk of liver disease.

The study does not establish that sorbitol is harmful for humans even when consumed in moderate amounts. In fact, sorbitol occurs naturally in fruits such as stone fruits, and the researchers noted that relatively low amounts are generally handled effectively by gut bacteria.

The findings challenge the assumption that sugar substitutes are automatically metabolically healthy simply because they contain less sugar or fewer calories.