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Who does not enjoy staying young? Especially when you can do it with just tweaking your diet a little! A recent study published in Nature Publishing Group Aging, reveals that a nutrient-rich diet, similar to the Mediterranean style plays an important role in slowing brain aging.
The study used blood biomarker analysis, brain imaging and cognitive assessments to conclude that specific nutrients like fatty acids, antioxidants, carotenoids, vitamin E, and choline, are essential to support healthy brain function and delay cognitive decline.
This was a cross-sectional study which involved 100 adults between the ages of 65 and 75. The participants were healthy and showed no evidence of cognitive impairment and they underwent several tests, including MRIs, mental tests and blood work. The researchers studied 139 variables of brain health, including brain metabolism, function, and structure.
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Fatty Acids: Vaccenic, gondoic, alpha-linolenic, eicosapentaenoic, eicosadienoic, and lignoceric acids, commonly found in plants, dairy, and oily fish, contribute to neuron maintenance.
Antioxidants and Carotenoids: Cis-lutein, trans-lutein, and zeaxanthin are essential for neutralizing free radicals and protecting the brain from oxidative stress.
Vitamin E: This antioxidant helps safeguard brain cells, with research suggesting its role in preventing dementias like Alzheimer's disease.
Choline: A vital nutrient for the neurotransmitter acetylcholine, which is important for memory and attention.
Experts affirm that these nutrients (mentioned above) are commonly found in the Mediterranean diet and are known for their neuroprotective properties. The Mediterranean diet has positive effects on brain, and there is enough evidence to prove that too. It is because the fatty acids maintain neurons, while the antioxidants combat oxidative stress, which then preserves brain function.
Choline, which is found in egg yolks are also essential for acetylcholine production, which supports cognitive functions such as memory and focus. There are certain nutrients which one can find in egg yolks that reduce oxidative stress and inflammation. Further, they also support cell membrane integrity and improve brain blood flow, which in turn enhances neuroplasticity. These are all crucial for healthy aging.
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There are also additional benefits too, for instance, omega-3 fatty acids also reduce heart disease risks, whereas antioxidants like vitamin C and E also boost immune system. The Mediterranean diet in all, also manages arthritis and metabolic syndrome.
Fatty Fish: These include Salmon, mackerel, sardines, and trout are rich in omega-3s.
Leafy Greens: These include spinach, kale, broccoli. These are packed with carotenoids like lutein and zeaxanthin.
Nuts and Seeds: They are rich in alpha-linolenic acid (ALA) and vitamin E. You can include almonds, sunflower seeds, and flaxseeds in your diet.
Eggs and Liver: They are a great source of choline, which can be helpful for brain function.
Colorful vegetables and fruits: Peppers, tomatoes, and oranges are rich in anti-oxidants and vitamin C.
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Our sleep can be influenced by what we eat, especially the quantity and timing of the food intake before bedtime; however, food is not the primary regulator of our sleep-wake cycle.
A large, heavy or fat-rich meal close to bedtime can prolong digestion and worsen acid reflux, which may fragment sleep. In contrast, a small, easily digested snack may be useful when someone is genuinely hungry before bed.
Certain foods containing tryptophan, which is a building block for serotonin, subsequently help in the production of melatonin in the body. Melatonin is the key regulator of our body’s sleep cycle. However, the effects of food-derived melatonin on human sleep are modest and less predictable than the body's own circadian melatonin secretion.
Emerging evidence shows that the timing of meals itself is relevant to circadian health. Later eating patterns are associated with poorer sleep outcomes.
Magnesium supports neuromuscular function and several pathways relevant to relaxation and sleep regulation. Scientific studies associate adequate magnesium status with better sleep, and studies have found a small improvement in insomnia symptoms with magnesium bisglycinate, particularly among people with lower dietary magnesium intake.
Tryptophan is an essential amino acid and a precursor of serotonin and melatonin. Evidence suggests that increasing tryptophan availability can modestly improve sleep, although the dose and specific population that will benefit remains controversial.
Carbohydrates may influence the availability of tryptophan to the brain. High-quality carbohydrates and fibre have generally been associated with better sleep, although the relationship is not straightforward. However this does not imply that eating a large amount of sugar before bed is beneficial.
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Tart cherries contain melatonin and polyphenols, and small clinical studies have reported improvements in sleep duration and efficiency. Chia seeds contribute fibre and magnesium, but there is no strong evidence that chia seeds itself is a sleep-promoting food. The juice portion should be kept modest, especially for someone with diabetes or glucose intolerance.
Milk provides protein and tryptophan. However, there is no convincing clinical evidence that nutmeg itself improves sleep. Consuming concentrated or large quantities of nutmeg can cause more harm than good.
This combination is biologically plausible as a light evening snack, as it is nutritionally well balanced. The pumpkin seeds provide magnesium and tryptophan, while the banana provides carbohydrate and potassium. However, the pumpkin seeds are calorie-dense, and so the serving should be kept moderate
Greek yoghurt, like milk, provides protein and tryptophan. Fermented dairy foods are associated with favourable dietary patterns, although direct evidence that Greek yoghurt itself improves sleep is limited. A small amount of honey provides carbohydrate, which may potentially assist tryptophan availability.
This provides a combination of carbohydrate, protein and healthy unsaturated fat. The carbohydrate component may support tryptophan availability, while the almond butter adds magnesium and protein.
A small study has found that eating two kiwi fruits about an hour before bed improved sleep onset, total sleep time and sleep efficiency. The mechanisms may involve antioxidants, serotonin and other bioactive compounds, but the evidence is still preliminary. It is naturally portion-controlled and relatively light, making it a practical evening option.
Oats provide complex carbohydrates, fibre and some magnesium, while chamomile has traditionally been used for relaxation. However, there isn’t strong evidence to call this combination a proven sleep therapy.
Walnuts contain melatonin, magnesium and healthy polyunsaturated fats, making them nutritionally interesting for sleep. A small handful is sufficient, as their high calorie and fat content makes large portions unnecessary before bed.
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For most people, I would recommend about 1–2 hours before bedtime, and the snack should be genuinely small, and it should not be a second dinner. For calorie-conscious people, the amount should be roughly 100 to 200 calories, depending on the individual’s need, activity level and reason for eating. The goal is to take the edge off hunger without creating substantial digestive work.
Are there foods on this list that could potentially disrupt sleep, digestion or blood sugar when consumed late at night?
It is important to note that the portion and timing of the food, along with individual metabolic health conditions, determine the effect of food on sleep to a much larger extent than the type of food itself.
However, having cherry juice and honey can produce a significant glucose load, especially in diabetic patients. This requires caution. Nut butter, walnuts, and pumpkin seeds are calorie-dense and rich in fat and hence can feel heavy close to bedtime.
Most importantly, any large snack eaten close to lying down can worsen reflux, particularly in people who already have gastroesophageal reflux disease. It is better to avoid meals within approximately 2–3 hours of bedtime in patients with reflux symptoms.
A bedtime snack is not necessary for everyone. It may be useful for someone who is genuinely hungry before bed, for people with increased energy requirements such as athletes during heavy training, or when a long gap between dinner and breakfast makes hunger interfere with sleep. In those situations, a small balanced snack can be preferable to going to bed uncomfortably hungry.
On the other hand, people with night-time reflux, significant indigestion, delayed gastric emptying, or difficulty controlling their calorie intake should generally avoid substantial food close to bedtime. People with diabetes should also individualise bedtime snacks according to their glucose-lowering therapy and glucose pattern rather than assuming that a bedtime snack is universally beneficial.
By Dr. Subho Sarkar, Consultant, Pulmonary & Sleep Medicine, Sir HN Reliance Foundation Hospital
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In India, vegetarian food is often considered a healthier choice, and many people believe that avoiding meat automatically reduces their risk of lifestyle diseases.
The traditional Indian vegetarian diet, rich in lentils, vegetables, whole grains and legumes, has long been seen as a cornerstone of good health. Yet India faces a staggering diabetes epidemic, with over 101 million people living with diabetes and millions more at the pre-diabetic stage. This contradiction is often called the "Indian vegetarian paradox". As doctors, we need to look beyond whether someone eats vegetarian or non-vegetarian food and understand what actually goes into their daily meals.
A person can follow a completely vegetarian diet and still be at risk of developing type 2 diabetes. This does not mean that vegetarian food is unhealthy. The root of the paradox lies not in vegetarianism itself, but in what makes up the contemporary Indian plate.
Traditional diets relied on complex carbohydrates, high fibre and unrefined grains. Modern eating habits have shifted heavily towards refined carbohydrates such as polished white rice, white flour (maida) and packaged snacks. Indian vegetarian cooking also often includes generous amounts of oil, ghee, full-fat dairy and sugar in sweets and beverages.
Consider a typical Indian meal. A large serving of rice or chapati, accompanied by a small portion of dal and limited vegetables, may look like a regular home-cooked meal.
However, if this pattern is repeated every day, the overall carbohydrate intake can become quite high. When the diet is also low in fibre and protein, it triggers sharp spikes in blood glucose after meals. Over time, these repeated spikes overwhelm the pancreatic beta cells and accelerate insulin resistance, making blood glucose harder to manage, particularly in people who already have insulin resistance.
Interestingly, the ICMR-INDIAB dietary study published in Nature Medicine in 2025, which analysed dietary patterns among 18,090 Indian adults, highlighted the high consumption of low-quality carbohydrates and relatively low protein intake in Indian diets. Its analysis also suggested that replacing a portion of carbohydrate intake with plant-based or dairy protein was associated with a lower likelihood of type 2 diabetes.
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Another misconception is that replacing white rice with millets or switching to whole wheat is enough to prevent diabetes. High-fibre millets and whole grains can certainly be part of a healthy diet, but the quantity consumed and the overall balance of the meal matter just as much. Simply changing the grain without addressing portion sizes may not make a significant difference.
We also need to pay attention to what people eat between meals. Biscuits, bakery products, packaged snacks and sweetened beverages are often considered harmless because they are vegetarian. However, many of these foods contain refined carbohydrates, added sugar, trans fats and excess calories.
There is also an important Indian-specific concern. Diabetes does not affect only people who are visibly overweight.
South Asians have a distinct metabolic profile, with more fat around the abdominal organs, more fat deposited in the liver and lower muscle mass relative to body fat.
This makes them more susceptible to type 2 diabetes even at lower body weights and BMI levels. Family history, physical inactivity and poor sleep can further increase the risk.
The answer is not to give up vegetarian food. Instead, we should focus on improving the quality of the diet by returning to nutrient-dense, traditional patterns. Including adequate portions of dal, whole legumes, beans, non-starchy vegetables, curd, nuts and seeds, while moderating refined carbohydrates, trans fats and added sugars, can make everyday meals more balanced.
Being vegetarian is a dietary choice, but preventing diabetes requires a more thoughtful approach to what we eat, how much we eat and how consistently we maintain a healthy lifestyle. Plant-based nutrition remains powerful, but only when it is balanced for metabolic health.
By Dr Hiran S. Reddy, Consultant Physician, Diabetologist & Critical Care Specialist, Gleneagles Hospital, Lakdi-Ka-Pul, Hyderabad
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From sugary mithai such as jalebi, gulab jamun, laddoo and barfi to fried foods such as puris and pakoras, Diwali is a time for gastronomic delight. While occasional indulgence is unlikely to cause lasting harm, overeating can strain the digestive system, health experts warn.
It can trigger acidity, bloating and indigestion. Excessive consumption of sugary foods can also affect blood sugar levels, particularly in people with diabetes.
Speaking to HealthandMe, two experts explain how festive overeating affects your body and how to ease digestive discomfort.
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Overeating stretches the stomach and may slow gastric emptying, particularly after fatty meals. This can cause heaviness, nausea and abdominal discomfort.
"Excessive consumption of samosas, kachoris, puris and rich gravies can cause heaviness, nausea, belching and abdominal discomfort," said Dr Parmeet Kaur, Chief Dietician, AIIMS.
Dr Ayush Dhingra, Chairman – Gastroenterology, Manipal Hospital, Gurugram, said large portions, eating too quickly and consuming excessive fried, fatty, spicy or sugary foods can trigger digestive discomfort.
Large meals distend the stomach, while fatty foods can delay gastric emptying and worsen reflux. Excessive consumption of chole bhature, pakoras, spicy curries and late-night snacks can trigger heartburn, a sour taste in the mouth and the sensation of food coming back into the throat.
Dr Dhingra said an excessively full stomach can aggravate acid reflux. Recurring symptoms may indicate gastroesophageal reflux disease (GORD) and require medical evaluation.
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Festive sweets such as jalebi, gulab jamun, laddoo and barfi can rapidly raise blood glucose levels, stimulating insulin secretion. Fried foods, including puris and pakoras, may prolong glucose elevations. Excessive fat intake can also temporarily reduce insulin sensitivity.
Dr Kaur cited a controlled human study in which one day of high-fat overfeeding increased glucose and insulin responses and reduced insulin sensitivity by 28%.
Sugary foods and beverages can also cause blood sugar spikes, making portion control particularly important for people with diabetes, Dr Dhingra told HealthandMe.
Excess calories from sweets, namkeen, fried snacks, rich gravies and sugary beverages can increase body weight.
However, initial weight gain may partly reflect water retention and increased glycogen stores rather than fat accumulation.
A systematic review of 39 studies found an average festive-period weight gain of approximately 0.7 kg, although individual outcomes varied. Repeated overeating can contribute to fat accumulation and affect metabolic health.
Mild bloating and indigestion may settle on their own, but persistent or severe symptoms should not be dismissed as ordinary indigestion.
Dr Dhingra cautioned that severe upper abdominal pain, particularly when it radiates to the back and is accompanied by nausea, vomiting or fever, could indicate pancreatitis.
Recurring acidity and indigestion also warrant medical evaluation rather than repeated self-medication.
Returning to regular eating habits rather than following restrictive diets can help your digestive system settle.
Dr Kaur recommends balanced meals comprising dal, roti, vegetable sabzi, curd and khichdi. Adequate hydration and fibre intake can also support digestion.
Dr Dhingra suggests the following measures:
Avoid crash diets or skipping meals to compensate for festive overeating. Return to balanced meals and regular eating habits instead.
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