A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.

The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.

The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.

Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:

"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.

Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.

"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.

Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."

One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:

"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."

Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.

These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.

Link Between Metabolism and Bipolar Disorder

Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.

One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.

What Is a Ketogenic Diet?

The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.

First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.

There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.

Sugary drinks are a very soothing option in summer, but come with several health-related issues like diabetes, fatty liver, and heart disease, to name a few. And now this list is getting a new addition, as a new study claims that sugary beverages can cause brain aging. This research is linked to the Framingham Heart Study.

As the Indian summer is in full sway, the demand for cold sugary drinks is also rising along with it. During the hot summer, people use these beverages as cooling drinks, and consumption also goes through the roof.

What Did The Study Find?

The researchers from the Boston University School of Medicine studied participants in the Framingham Heart Study Offspring and the Third Generation Study. The research was done on the possible impacts that sugar-sweetened beverages (SSBs) and artificially sweetened beverages (ASBs) have on the brain.

The study finds that consuming a large amount of sugary drinks was associated with a smaller total size of the brain and reduced volume of the hippocampus, which is a critical region in the brain essential for learning and memory.

The research points out that consuming too many sugary drinks can lead to inflammation, poor blood vessel function, and high blood sugar, which in turn might harm the brain.

Which Drinks Are Considered As Sugary Drinks?

Sugary drinks or sugar-sweetened beverages (SSBs) are drinks that are added with sugar, sweeteners, or syrups. Some of the common sugary beverages are carbonated soft drinks, energy or sports drinks, and fruit-flavored drinks.

How to Cut Back on Sugary Drinks

Sugary drinks can feel addictive. If you find yourself hooked, try to slowly reduce how much you drink, just like you would with alcohol or tobacco. It helps to plan ahead for when you usually crave a soda.

You can start by mixing plain sparkling water with an equal amount of fruit juice or soda. Then, week by week, slowly reduce the amount of the sugary drink until you're mostly just drinking sparkling water. If it helps, add a little lemon or lime juice for flavor. Make this your new habit.

The data from the Centers for Disease Control and Prevention (CDC) shows that almost half the population of the United States has high blood pressure, numbering around 119.9 million people, who are suffering from this disease. The data also reveals that over 660,000 deaths occur every year. Thus, keeping your blood pressure under check is a necessity, and beetroot, along with some leafy greens, can help you in this.

A recent study conducted by the University of Exeter found that drinking beetroot juice twice daily can help lower blood pressure in older adults in just a fortnight. The findings of this study were published in the journal Free Radical Biology and Medicine.

The study was conducted with 75 volunteers from different age groups. They belong to the age bracket of 30s to 60s and 70s. The researchers asked each person to complete two separate two-week trials. In one of the two weeks, they were given nitrate-rich beetroot juice, and in the other week, it changed to a placebo version with the nitrate removed.

Benefits Of Drinking Beetroot Juice

• Beetroot is naturally high in nitrates, which the body converts into nitric oxide. This compound relaxes and widens blood vessels, improving circulation and reducing blood pressure.

• Beetroot juice contains betalains, natural pigments with anti-inflammatory properties.

• Beetroot contains iron, an essential component of red blood cells, which helps transport oxygen throughout the body. Low iron levels can lead to iron deficiency anemia, resulting in symptoms such as fatigue, dizziness, and shortness of breath.

• Beetroot juice may help manage nonalcoholic fatty liver disease (NAFLD).

Benefits Of Adding Spinach to Your Diet

• The potassium in spinach helps relax blood vessels, leading to lower blood pressure. Spinach is also high in magnesium and folate, which support the production of nitric oxide—a molecule that dilates blood vessels and promotes better circulation.

• Spinach provides a significant amount of vitamins and minerals with minimal calories. This makes it an ideal food for those looking to maintain a healthy weight while getting ample nutrients.

• Spinach is rich in antioxidants such as beta-carotene and lutein, which protect against cell damage caused by free radicals.

• Spinach is high in fiber, with about 2 grams per serving. Insoluble fiber helps improve digestion by adding bulk to stools and preventing constipation.

• The lutein and zeaxanthin in spinach, antioxidants related to vitamin A, help protect the eyes from sun damage and age-related disorders like cataracts and macular degeneration.

• Spinach is an excellent plant-based source of iron, essential for producing haemoglobin in red blood cells. This helps prevent iron-deficiency anemia, which can cause fatigue.

Summer brings not just a temperature change, but also a change in energy. Ayurveda, the ancient Indian study of life and health, says that each season has its main dosha, or bio-energetic force. Summer is the time of Pitta — the dosha ruled by the elements of fire and water. Dr Mandeep Singh Basu, Director, Jagat Pharma, in an interview with Health and Me, listed some of the best desi foods that can help you beat the heat and stay hydrated even in peak summer.

In summer, the goal is to favour sheeta (cooling), laghu (light), and snigdha (mildly unctuous) foods. They balance Pitta's hot, furious, and acute qualities. In Ayurveda, there are six tastes: sweet, sour, salty, pungent, bitter, and astringent. All six tastes have a relationship with Pitta. Sweet, bitter, and astringent are the flavours of summer.

Let us look at the superfoods of summer from this viewpoint.

Coconut Water

The most famous summer drink in Ayurveda is probably coconut water. It is categorised as a tridoshic drink. It balances all three doshas but is highly prized for its capacity to soothe Pitta and restore ojas, the vital essence of immunity and vigour. Coconut water is packed with natural electrolytes, potassium, magnesium, and sodium, replenishing what perspiration leaves behind.

Drink fresh tender coconut water in the mid-morning or as an afternoon refresher. Do not drink it cold from the refrigerator. Room temperature or slightly cool coconut water is recommended for the best absorption.

Cucumber

More than 95% of a cucumber is water, and it is known for its cooling energy, which Ayurveda has long understood. It cools internal heat, soothes irritated digestive tissue, and improves renal function, all of which are important in summer when the body is under heat stress.

Modern nutritionists would say that cucumber is also a source of silica for skin health, vitamin K, and antioxidants like cucurbitacins. But in Ayurveda, its Pitta-shamaka (Pitta-pacifying) quality is most appreciated — it literally cools the gut, the blood, and the skin from the inside out.

Have cucumber slices with a pinch of rock salt (sendha namak) and fresh mint. Mix it into raita with cooling coriander and cumin. According to Ayurveda, you should not consume cucumber at night as it may slow digestion.

Watermelon

Tarbuj is known for its sweet, cooling, and hydrating nature. One of the most generous gifts of summer is watermelon, a fruit that contains approximately 92% water and is a source of lycopene, a potent antioxidant that helps protect against UV damage. Watermelon is a natural Pitta pacifier and a mild urinary tract detoxifier in Ayurveda.

It is classed as sheeta virya (cold potency) and is considered helpful for burning sensations in the body, such as heartburn, skin redness, and excessive thirst. The seeds, which are generally discarded, are treasured in Ayurveda. They are dried, powdered, and consumed as a kidney tonic.

Eat watermelon on its own. It is best eaten alone in the late morning. Ayurveda also recommends against pairing watermelon with dairy, cereals, or other fruits because it digests best alone. A squeeze of lime and a pinch of black salt may be added for flavour.

Mint

Ayurvedic Quality: Cool, light, pungent in taste but cooling in effect.

Mint is one of Ayurveda's most fascinating paradoxes — it tastes pungent (which would ordinarily aggravate Pitta), but its virya, or post-digestive potency, is deeply cooling. This makes it uniquely suited for summer use. It stimulates digestion without generating heat, relieves nausea, clears the respiratory tract, and cools the mind. Modern science confirms that its menthol content activates cold-sensing receptors in the body, creating a genuine cooling sensation.

You can consume mint in the form of freshly brewed mint tea (cooled to room temperature), blend it into chutneys with coriander and coconut, or add it to cooling drinks like aam panna or shikanji. Mint-infused water kept in a clay pot (matka) is a classic Ayurvedic cooling remedy.

Amla (Indian Gooseberry)

Amla is one of the most remarkable foods in the Ayurvedic pharmacopoeia. Its virya is cooling, meaning it has a unique ability to soothe rather than inflame, even though it is sour — a taste that normally aggravates Pitta. It is the main constituent in two of the most revered Ayurvedic formulations, Chyawanprash and Triphala.

Amla is the richest natural source of vitamin C among fruits, containing about 600–700 mg per 100 grams. A large proportion of this vitamin C is heat-stable because tannins in the berry protect it during digestion and cooking. It safeguards the liver, enhances skin clarity, and bolsters immunity — all of which are challenged by the demands of summer.