A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.

The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.

The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.

Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:

"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.

Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.

"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.

Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."

One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:

"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."

Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.

These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.

Link Between Metabolism and Bipolar Disorder

Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.

One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.

What Is a Ketogenic Diet?

The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.

First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.

There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.

Love your daily cup of coffee? The way you brew it could make a difference—not just for its taste, but also for your cholesterol levels.

A new scientific statement from the American Heart Association (AHA), published in the peer-reviewed journal Circulation, stated that for most healthy adults, drinking up to five cups of black caffeinated coffee a day (up to 400 mg of caffeine) is safe and may even benefit heart health.

However, the statement, based on a review of the latest evidence on caffeine and cardiovascular health, noted that the brewing method matters because some types of coffee contain compounds that can raise LDL, or "bad," cholesterol.

Black Coffee May Benefit Heart Health

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According to the AHA, moderate consumption of black, caffeinated coffee without added sugar, cream, or flavored syrups has been linked to several cardiovascular benefits.

A review of the latest evidence found that drinking three to five 8-ounce cups of regular black coffee daily was associated with a lower risk of:

• Heart disease
• Stroke
• Heart failure
• Type 2 diabetes
• Some abnormal heart rhythms.

"Caffeine consumed in coffee is a key part of daily life for millions of people, and in our review of the most recent research, for most adults, intake of up to 400 mg of caffeine/day, the equivalent of up to five cups of caffeinated coffee per day without added sugars or fillers, is safe and does not increase cardiovascular risk," said Gregory M. Marcus, chair of the scientific statement writing group and professor of medicine at the University of California, San Francisco.

Why Brewing Method Matters

While coffee itself may support heart health, the AHA highlighted one naturally occurring compound—cafestol—that can raise LDL ("bad") cholesterol.

Cafestol is found in both caffeinated and decaffeinated coffee, but its levels depend on how the coffee is prepared.

Cafestol, associated with increased LDL cholesterol levels, is high in unfiltered coffee, including:

• French press
• Espresso
• Turkish coffee
• Boiled coffee

In contrast, paper-filtered coffee and instant coffee contain little to no cafestol, making them a better choice for people concerned about cholesterol.

Read More: US Cardiologist Explains Why 2026 AHA Cholesterol Guidelines Recommend Starting Young

Coffee And Blood Pressure

The statement also found that coffee's effect on blood pressure is complex, and they called for more studies to better understand this relationship.

Yet the findings revealed that among people with normal blood pressure, drinking one to three cups a day was associated with a higher risk of developing hypertension, while consuming more than three cups daily was linked to a lower risk.

Coffee May Lower Diabetes Risk

Although caffeine may temporarily reduce insulin sensitivity, regular consumption of black caffeinated coffee has been linked to a lower risk of Type 2 diabetes. Researchers believe this benefit is likely due to compounds in coffee other than caffeine.

Energy Drinks Are Not the Same

The AHA cautioned that the findings do not apply to energy drinks or energy shots. These products contain much higher concentrations of caffeine—around 40–69 mg per fluid ounce, roughly three to four times more than regular brewed coffee—and have been linked to high blood pressure, abnormal heart rhythms, and other cardiovascular risks, even in healthy adults under 30.

No Universal Recommendation

Marcus stressed that there is no one-size-fits-all recommendation for caffeine intake because people respond differently based on age, genetics, medications, underlying health conditions, and how quickly they metabolize caffeine.

He advised people to pay attention to how their body responds to caffeine and discuss their intake with their healthcare provider if they experience symptoms such as palpitations, anxiety, or sleep disturbances.

Nutritious food has become up to 25% more expensive over the past five years, leaving nearly one-third of the global population unable to afford a healthy diet, according to a new report released by the United Nations.

The 2026 State of Food Security and Nutrition in the World, published by the UN Food and Agriculture Organization (FAO), estimates that a healthy diet now costs an average of US$4.28 (S$5.52) in purchasing power parity (PPP) dollars per person per day.

"A healthy diet costs 25% more than it did five years ago. One-third of the global population can't afford it. The cost of a healthy diet shows where agrifood systems investments can have the greatest impact," Máximo Torero Cullen, the FAO's Chief Economist, wrote in a post on social media platform X.

What Are The Key Findings?

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The full report, to be presented on July 21 at the organization's headquarters in Rome, found that the cost of a healthy diet is unevenly distributed across different food groups.

• Staple foods, including grains and legumes, account for 13% of the total cost.

• Animal-source foods make up nearly 30%, making them the largest cost component.

• Fruits and vegetables contribute about 16% of the overall cost.

"The challenge is not to produce enough calories; it is to make nutrient-rich foods more affordable," Torero said during a press conference, as quoted by AFP. The full report will be presented July 21 at the organization's headquarters in Rome.

He emphasized that strengthening local food production could significantly lower the cost of healthy diets.

Torero also highlighted two major uncertainties that could further drive up global food prices:

• A potential disruption in fertilizer supplies if the Strait of Hormuz faces prolonged closure amid tensions involving Iran

• The impact of a strong El Niño weather pattern, which is expected to peak toward the end of 2026.

Healthy Eating to Prevent Chronic Disease: One Size Doesn't Fit All

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While eating a healthy diet is widely recommended to reduce the risk of chronic diseases, experts say there is no one-size-fits-all approach. Nutritional needs vary based on factors such as age, health status, activity level, and cultural preferences.

According to Harvard Health, the key principles of a healthy diet include:

• Eating plenty of plant foods: Vegetables, fruits, legumes, whole grains, nuts, and seeds provide vitamins, minerals, fibre, and beneficial plant compounds known as phytochemicals

• Getting enough protein: Adequate protein intake, combined with regular physical activity, helps maintain muscle strength, overall health, and independence as people age

• Avoiding processed foods: Prioritize whole and minimally processed foods over ultra-processed products, which often contain excess sugar, unhealthy fats, sodium, and preservatives while offering fewer nutrients

• Limiting saturated fats, added sugars, and sodium: The US Dietary Guidelines recommend keeping saturated fat and added sugar intake to less than 10% of daily calories while reducing sodium intake.

• Focus on balance and variety: Eating a diverse range of nutrient-dense foods across all food groups helps meet nutritional needs without consuming excess calories.

Amid intensified inspections and market surveillance by the Food Safety and Standards Authority of India (FSSAI) to crack down on counterfeit and substandard dairy products, a new survey has found that 6 in 10 urban Indian households are not fully confident about the purity and quality of the ghee or clarified butter they consume.

The survey, conducted by community social media platform LocalCircles, received over 91,000 responses from more than 18,000 urban consumers across 293 districts, revealing widespread concern over adulteration—particularly in loose and unbranded ghee.

Survey Findings

According to the survey:

• 60% of urban households said they are only partially confident or not confident about the purity and quality of ghee.
• Consumers expressed greater concern about loose or unbranded ghee, which is perceived to be at higher risk of adulteration.

The findings come amid a series of enforcement actions by FSSAI targeting fake and substandard dairy products across India.

Also read: India Gets Its First Plant-Based Vitamin D3: What You Need to Know

FSSAI Intensifies Action Against Adulterated Ghee

In December 2025, FSSAI directed all States and Union Territories to launch a nationwide enforcement drive against the adulteration and misbranding of milk and milk products, including ghee, paneer and khoya, under the Food Safety and Standards Act, 2006.

Since then, the regulator has significantly expanded inspections and surveillance. Recent enforcement actions include:

• June 2026: FSSAI busted a counterfeit ghee network operating across Delhi and Haryana, seizing over 6,500 litres of suspected adulterated ghee. Laboratory testing found samples mixed with vegetable oils and other non-dairy ingredients.
• July 2026: FSSAI seized more than 50,000 food and non-food products in Delhi over fraudulent relabelling and improper storage. Around the same time, Delhi Police dismantled a syndicate that allegedly altered manufacturing and expiry dates on packaged goods before supplying them to retail and e-commerce markets.
• November 2025: Authorities uncovered a major fake ghee racket in Bengaluru operating under the Nandini brand name, seizing over 8,000 litres of suspected adulterated ghee and machinery allegedly used to manufacture counterfeit products.

FSSAI has also issued notices to quick-commerce platforms over complaints of expired and spoiled food products being delivered to consumers.

Is Ghee Healthy?

Made by clarifying butter obtained from cow's milk, ghee is a staple in Indian kitchens and contains approximately 130 calories and 15 grams of fat per tablespoon. It is also a rich source of vitamins A, D, E and K, along with antioxidants.

However, because ghee is high in saturated fat, excessive consumption may raise LDL ("bad") cholesterol levels in some individuals and increase the risk of cardiovascular disease.

Read More: Michigan Health Officials May Have Traced The Possible Source Behind Massive Cyclospora Outbreak

Who Should Limit or Avoid Ghee?

Health experts advise people with certain medical conditions to consume ghee cautiously or avoid it altogether.

These include people with:

• Heart disease
• High cholesterol
• Obesity
• Chronic kidney disease
• Certain digestive disorders
• Liver conditions such as jaundice

Doctors generally recommend limiting intake to no more than two teaspoons a day, unless advised otherwise by a healthcare professional.

Health Risks of Adulterated Food

Food adulteration involves the deliberate addition of inferior or harmful substances to food products, compromising their quality and safety.

According to a 2024 study published in SAGE Open Medicine, consuming adulterated food may increase the risk of:

• Cancer
• Liver disease
• Kidney disease
• Cardiac failure
• Lathyrism
• Nervous system disorders
• Allergic reactions

The study notes that children, pregnant women and older adults are particularly vulnerable to the harmful effects of adulterated food.