A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.

The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.

The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.

Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:

"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.

Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.

"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.

Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."

One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:

"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."

Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.

These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.

Link Between Metabolism and Bipolar Disorder

Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.

One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.

What Is a Ketogenic Diet?

The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.

First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.

There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.

Festivals bring family and friends together and all enjoy traditional sweets and savouries to rich gravies and deep-fried delicacies. However, the joy of celebration and eating more than regular can sometimes lead to bloating, acidity, heaviness, gas and discomfort. Understanding how digestion works and how Ayurveda explains it through the concept of Agni can help us celebrate with smoothness in our digestive system.

During festival, we may eat larger portions, enjoy several rich dishes at one meal, or eat again before we feel actual hunger. Digestive discomfort often occurs when we eat food without knowing agni, consume fatty or fried foods, eat too quickly or combine multiple rich dishes in one meal, untimely, without proper digestion of previous meal. For some people, carbonated drinks and particular food can increase gas or bloating. Stomach stretches when we overeat, and high-fat and heavy meals may delay stomach emptying, leaving us feeling uncomfortably full for longer period. Eating rapidly can also cause us to swallow more air. For people prone to acid reflux, large meals may get worsen with heartburn and regurgitation. Occasional bloating after a heavy meal is common.

Ayurveda explain digesting and metabolism through concept of Agni. The concept of Jatharagni relates particularly to the digestion and metabolism of food. Ayurveda also describes Mandagni (diminished digestive capacity) which will be associated with symptoms such as heaviness, reduced appetite and sluggish digestion etc..., from a practical perspective, the Ayurveda emphasis on eating according to digestive capacity, avoiding excessive food intake and maintaining regular dietary habits aligns sensibly with modern nutrition advice. Classical ayurvedic text emphasise the importance of maintaining balance Agni, for overall health, well-being and preventive care; however, Agni is a traditional Ayurvedic concept and should not be directly corelated with any single modern physiological process.

Also read: We Fact Checked The Ayurveda Claim Of Papaya Lowering Your Cholesterol, Details Inside

Five Healthy Eating Habits For Festive Season

1. Portion awareness: Enjoy your favourite dishes of festival but begin with moderate portions. Eat in moderate speed and pause before taking a second serving.

2. Avoid excessive food in one sitting: Multiple preparations which are fried and sugary can make a meal unnecessarily heavy. Choose a balanced plate with vegetables, protein-rich foods and appropriate portions of carbohydrates and Fats.

3. Hydration: Drink warm water regularly throughout the day sip by sip. Limit excessive carbonated beverages if they are causing any discomfort or not.

4. Digestion time: Avoid lying down immediately after meals. A gentle 10–15-minute slow walk after eating may support general digestive comfort, then if needed lie-down on left sided.

5. Routine and mindful eating: Avoid skipping meals to compensate for feasting. Eat when comfortably hungry after analysing agni, pay attention to fullness and maintain regular sleep, physical and mindfulness activities.

Festive eating need not mean deprivation or discomfort. Ayurveda's emphasis on Agni encourages us to respect individual digestive capacity, and guidance from nutrition reinforces moderation, mindful eating and balanced meals. Enjoy the foods you love, savour every bite, observe and recognise when you are comfortably full of stomach.

Seek medical evaluation if bloating is persistent, frequently recurring or accompanied by severe abdominal pain, repeated vomiting, diarrhea, blood in the stool, unexplained weight loss, difficulty swallowing or any GI related symptoms. Severe or sudden abdominal pain requires urgent medical attention and assessment.

This festive season, let celebration nourish your well-being not leave you feeling weighed down.

Disclaimer: This article is for informational purposes only and is not a substitute for professional medical advice.

According to Indian food regulations, there is a specified amount of pesticide residue that can legally remain in tea leaves. But the Food Safety and Standards Authority of India (FSSAI) has proposed new limits for two types of pesticides used in agriculture, including a limit for one that is lower than those in the United States and Japan.

The draft amendment, announced by the Ministry of Health and Family Welfare on October 17, 2026, proposes maximum residue limits (MRLs) for acetamiprid and imidacloprid in tea. The move is aimed to give tea farmers, manufacturers and regulators clearer standards to follow.

Under the proposal, the maximum permitted residue of acetamiprid in tea would be 20 milligrams per kilogram (mg/kg), or 20 parts per million (ppm). For imidacloprid, the proposed limit is 50 mg/kg.

The draft regulations were published in the Gazette of India on October 16 and are yet to be finalised. These are proposed legal limits, not measurements showing how much pesticide is present in tea sold in India.

India's Proposed Limits For Pesticide Residue In Tea

India has proposed a limit of 20 ppm for acetamiprid, which is lower than the corresponding limit of 30 ppm in Japan and 50 ppm in the United States. For imidacloprid, the proposed Indian limit has been formulated with reference to international Codex standards.

These figures do not mean that tea sold in the US or Japan necessarily contains more pesticide residue. Maximum residue limits specify the highest concentration legally permitted in a food product. Actual residue levels depend on pesticide use, farming practices, and testing results.

A higher legal limit also does not automatically mean that a food product is unsafe. Risk assessment requires additional information about the pesticide, the amount consumed, the level of exposure and its toxicological profile.

The proposed tea standards are part of FSSAI's review of pesticide residue regulations. The government said an earlier regulatory measure aimed at delisting 13 pesticides that were known to have higher toxicity.

The regulator also highlighted India's comparatively low average pesticide use, at less than 0.5 kg per hectare, against an estimated global average of 2.38 kg per hectare.

Also read: Your Protein Powder May Be Toxic! A New Study Reveals High Levels Of Lead And Cadmium

What Are Acetamiprid And Imidacloprid?

Acetamiprid and imidacloprid belong to a class of insecticides called neonicotinoids. They are used to control agricultural pests. Although they help protect crops, their safety depends on how they are used, the residues left behind and the amount people are exposed to.

Acetamiprid acts on the nervous system of insects. Toxicological research has raised concerns about its potential effects on the nervous system and reproductive development at sufficiently high exposure levels.

Imidacloprid also works the same way and its excessive exposure can cause toxic effects, including neurological symptoms.

The health risks stem from long-term, low-level exposure that depend on the dose, way of exposure and duration. The proposed residue limit alone cannot establish whether a particular tea product poses a health risk.

Also read: Blueberries To Green Beans: Fruits & Vegetables With Maximum Pesticide Content

Health Risks Of Pesticide Residues In Tea

The health risks associated with pesticide residues depend on the chemical involved and how much enters the body. High exposure to certain insecticides can affect the nervous system, while toxicological studies have also investigated possible effects on reproduction.

For consumers, the key question is whether pesticide exposure through food remains within levels considered acceptable under established safety assessments.

Maximum residue limits are designed to help regulate pesticide use. They are generally set using data on pesticide use, residue levels, dietary exposure and toxicological assessments.

The actual exposure for tea drinkers also depends on how much residue remains in the dry leaves and how much transfers into the brewed drink. Residue levels in dry tea cannot be directly compared with the amount consumed in a cup.

McMaster University’s release names packaged snack foods, sugary breakfast cereals, soft drinks, instant noodles and ready-to-eat frozen meals as examples of ultra-processed food.

What counts as ultra-processed

Chips, sweet breakfast cereals, processed sweet yogurts, soft drinks, instant noodles and frozen ready meals all fall under the ultra-processed category, according to Russell de Souza, a health research professor at McMaster University and registered dietitian, speaking to CTV News.

What the study found

McMaster University’s release names packaged snack foods, sugary breakfast cereals, soft drinks, instant noodles and ready-to-eat frozen meals as examples of ultra-processed food.

The study was led by McMaster’s Population Health Research Institute (PHRI) and enrolled nearly 9,000 Canadians aged 35 to 69 with no history of heart disease, according to McMaster. Participants came from two PHRI studies, the Canadian Alliance for Healthy Hearts and Minds and the Prospective Urban and Rural Epidemiology-MIND study. Each completed detailed dietary questionnaires and had an MRI brain scan, reviewed by neurologists who didn’t know their diets.

Also Read: Ozempic Baby: Can GLP-1 Drugs Help Women With PMOS Conceive?

Published October 15 in JAMA Network Open, the study found that participants with the highest intake were 40 per cent more likely to show tiny areas of brain damage than those who ate the least, per McMaster. These changes cause no obvious symptoms. They are considered early warning signs that can appear years before a stroke or memory problems.

Ultra-processed food made up about 25 per cent of participants’ daily food servings on average. For the heaviest consumers it was 45 per cent, compared with 16 per cent for the lowest group, McMaster reported.

Ultra-processed food made up about 25 per cent of participants’ daily food servings on average. For the heaviest consumers it was 45 per cent, compared with 16 per cent for the lowest group, McMaster reported. As intake rose, whole-food intake fell. Fruits, vegetables, grains and other minimally processed foods made up 41 per cent of daily servings in the highest-intake group, against 68 per cent in the lowest. Russell J. de Souza said this suggests ultra-processed foods displaced healthier whole foods rather than simply being eaten on top of a usual diet.

“I would not have expected this finding, frankly,” said de Souza, who is also an associate scientist at PHRI. The participants were middle-aged Canadians with no heart problems and no other reported health concerns, he noted. He added that this kind of damage is usually associated with conditions seen at a much older age, according to McMaster.

A stronger link in women

The association between ultra-processed food and brain damage appeared stronger among women. Those in the highest consumption group were nearly twice as likely to show signs of brain damage as those in the lowest, according to McMaster.

Participants with the highest intake also carried more body fat and more deep belly fat. McMaster’s release says this fat is linked to inflammation and blood vessel damage that can also reach the brain.

Senior author Sonia Anand, a senior scientist at PHRI, said the findings suggest the link between diet and brain health may be detectable before people notice memory or thinking problems. She said it adds to evidence that what Canadians eat from their 30s through their 60s shapes brain health later in life, per McMaster.

Correlation, not yet proof

Because participants were assessed only once and not followed over time, the researchers couldn’t determine whether ultra-processed food directly causes these brain changes, McMaster noted. De Souza said longer-term studies with repeated MRI scans are needed to find out whether cutting back can slow or prevent them. He said such follow-up is ongoing.

Speaking to CTV News, Anand said some participants whose diets were more than 45 per cent ultra-processed showed a combination of silent stroke and a pre-stroke profile. She said the team observed an independent effect of ultra-processed food on the damage seen in the scans. In the same interview, de Souza acknowledged that avoiding these foods isn’t equally easy for everyone, with many people struggling to make ends meet. He encouraged eating at home, buying local and using supermarket sales. Some participants are now returning for follow-up MRIs, with results expected in early 2028.