A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.

The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.

The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.

Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:

"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.

Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.

"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.

Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."

One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:

"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."

Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.

These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.

Link Between Metabolism and Bipolar Disorder

Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.

One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.

What Is a Ketogenic Diet?

The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.

First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.

There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.

Kate Middleton visited a brewery, London beer hall. The princess of Wales shared her new approach to alcohol and said, "Since my diagnosis, I haven't had much alcohol. It's something I have to be a lot more conscious of now."

In March 2024, Kate Middleton shared her cancer diagnosis. "It has been an incredibly tough couple of months for our entire family, but I’ve had a fantastic medical team who have taken great care of me, for which I’m so grateful,” her message began. “In January [2024], I underwent major abdominal surgery in London, and at the time, it was thought that my condition was noncancerous. The surgery was successful. However, tests after the operation found cancer had been present. My medical team therefore advised that I should undergo a course of preventive chemotherapy, and I am now in the early stages of that treatment.”

She said that her diagnosis was a "huge shock" for her family and that recovery form such a major surgery took a lot of time.

In January 2025, she announced that she was in remission. “It is a relief to now be in remission, and I remain focused on recovery,” she wrote on her Instagram account. “As anyone who has experienced a cancer diagnosis will know, it takes time to adjust to a new normal. I am, however, looking forward to a fulfilling year ahead. There is much to look forward to. Thank you to everyone for your continued support.”

Alcohol And Cancer

In 1987, the International Agency for Research on Cancer (IARC) classified alcohol as a Group 1 carcinogen, meaning there is sufficient evidence that it causes cancer in humans. Research has linked alcohol consumption to cancers of the oral cavity, pharynx, larynx, esophagus (particularly squamous cell carcinoma), and liver.

Although the level of risk varies between light, moderate, and heavy drinkers, the association between alcohol and cancer has been well documented for decades. In light of this evidence, Middleton appears to have reconsidered her relationship with alcohol following her diagnosis, remission, and recovery.

Scientific evidence continues to reinforce these concerns. According to the National Cancer Institute, alcohol consumption can increase the risk of several cancers, and the risk rises with greater intake. Even light drinking may carry some risk. For instance, studies show that women who consume one alcoholic drink a day have a higher risk of breast cancer compared with those who drink less than once a week, with the risk increasing further among heavy and binge drinkers.

Data from the United States also highlights the scale of the impact. Alcohol was estimated to be responsible for about 5% of the 1.8 million cancer cases diagnosed in 2019, as well as around 4% of cancer-related deaths that year. Research consistently shows that people who consume alcohol face higher risks of several cancers compared with those who do not drink.

The following table shows the risk of cancer and consumption of alcohol as per the National Cancer Institute data:

Water Stacking, a new term , a new trend comes up, after we have already reached the peak of "maxxing". If you have been keeping up with social media wellness trend, then you must be aware of the water stacking trend. For the uninitiated, this is a viral #WaterTok trend which started on the social media platform TikTok, that involves elevating plain water with various supplements, electrolytes, collagen, and flavoring the enhance hydration. For those who struggle to drink water and keep themselves hydrated, this is a trend which could help them stay on top of their hydration game.

Who Created Water Stacking Trend?

The trend was created by food scientist and content creator Jeffrey Ma. Ma says stacked water is a combination of different functional ingredients and juices added to water that enhances the hydration experience. Ma has worked in natural product industry for more than a decade and this is how he has come up with this idea that lets you get all your nutrients, simply through water.

In an interview with Vogue, he says, "It really came from me being lazy and wanting to mix everything into one tasty all-in-one drink." How did he come up with the ingredients, you ask? This is his answer: "I'm in my mid-30s and once you get past your 20s, it feels like there are more preventative supplements to think about (collagen for skin, joints and hair; vitamin C for immunity; fiber; protein; creatine; probiotics; electrolytes), while also trying to eat enough fruit and drink enough water each day. At the same time, I was working out a lot for Hyrox (a fitness competition), running, playing pickleball, and doing HIIT, so I genuinely needed daily electrolytes."

Read: Why The Social Media Trend Of Parents Shaving Children's Facial Hair Could Go Wrong

How To Make Your Own Stacked Water?

Think of it as a detox drink. You can customize your drink as per your needs. A bottle of stacked water does not have to be the same for everyone. Yours might include the nutrients you need, whereas someone else could have a completely different set of ingredient. The aim is to ensure that you get all your nutrients and the tasty water will make it easier for you to stay hydrated.

Jeffrey Ma on his Instagram (@heyjeffreyhouse) shared how people can use ingredients to make their own stacked water:

• Blended carrot
• 2 tsp Collagen peptides
• Lime or orange juice
• 1 Yakult
• 1 scoop creatine (optional)
• ½ tsp sea salt for electrolytes
• ½ tsp vanilla
• Lots of ice
• Just mix everything, and your stacked water is ready

You can customize your drink using chia seeds to add more fiber or chopped fruits to give it a little texture. The best part? It suits best for a summertime drink!

Note: Please consult your nutritionist and doctor before adding any extra supplements or nutrients to your daily water intake. Health and Me Does NOT promote a user-generated content as a substitute for medically verified hydration techniques.

David Protein Bars is facing a lawsuit that alleged that the company misrepresented the calorie and fat contents. It is a challenge for a company which is known for catering health-conscious customers.

The complaint was filed on January 23 in the US District Court for the Southern District of New York. Three individuals who bought David bars claimed that the protein bars contained "way more" calories and fat than the label noted.

Also Read: What Is the Viral Water Stacking Trend?

As per CBS News, independent and third-party testing used a method called Atwater factors. The result showed that the number of calories exceeded the amount listed on the label as much as by 83 per cent.

Fat Content In David Protein Bars

The lawsuit alleged that David Protein underestimated the fat content, as the testing revealed that the fat content exceeded by as much as 400 per cent.

As per the David Protein's website and the product label, the bar is supposed to contain 150 calories, 28 grams of protein and 0 grams of sugar. The lawsuit also stated Food and Drug Administration (FDA) guidelines that dictate that a product is misbranded if the "nutrient content of the composite is greater than 20% in excess of the value for that nutrient declared on the label."

The lawsuit names Linus Technologies as the primary defendant. The nutrition-focused company was founded by entrepreneur Peter Rahal in 2023, according to market intelligence platform Tracxn. It operates under the brand name David Protein.

Neither Linus Technologies nor David Protein immediately responded to requests for comment as reported by CBS News. However, on Wednesday the company posted a statement on Instagram that said, “No one is getting Regina Georged,” referencing the film Mean Girls, where the character Cady Heron tricks Regina George into eating a protein bar that leads to weight gain.

After the lawsuit was filed in January, Rahal told Vanity Fair that the company stands by the accuracy of its product labeling and plans to strongly contest the claim.

The David Protein bar was launched in 2024. According to Forbes, its name is inspired by Michelangelo’s famous 16th-century sculpture David.

The bars are sold in several flavors, including chocolate chip cookie and fudge brownie. A pack of 12 bars retails for $39, which works out to about $3.25 per bar.

Clear Information On Labels

FDA last year announced that in the coming next few years, food manufacturers have to put nutritional labels on the front of packaged foods. This proposal by FDA comes in the content of chronic diseases and the need for combating the same. The front-of-package labels are required for "most packaged foods", said the announcement.

Read: FDA Wants Nutrition Labels Of Saturated Fat, Sodium, And Added Sugar On Food Packaging

This announcement makes it easier for the customer to read the nutrition box that could otherwise go unnoticed, with many thinking that they are consuming something healthy. In most cases nutrition boxes are placed behind the packaging, and many ignore the content and thus continue to consume products with the presumption that it is healthy.