A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.
The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.
The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.
Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:
"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.
Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.
"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.
Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."
One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:
"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."
Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.
These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.
Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.
One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.
The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.
First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.
There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.
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Amid intensified inspections and market surveillance by the Food Safety and Standards Authority of India (FSSAI) to crack down on counterfeit and substandard dairy products, a new survey has found that 6 in 10 urban Indian households are not fully confident about the purity and quality of the ghee or clarified butter they consume.
The survey, conducted by community social media platform LocalCircles, received over 91,000 responses from more than 18,000 urban consumers across 293 districts, revealing widespread concern over adulteration—particularly in loose and unbranded ghee.
According to the survey:
The findings come amid a series of enforcement actions by FSSAI targeting fake and substandard dairy products across India.
Also read: India Gets Its First Plant-Based Vitamin D3: What You Need to Know
In December 2025, FSSAI directed all States and Union Territories to launch a nationwide enforcement drive against the adulteration and misbranding of milk and milk products, including ghee, paneer and khoya, under the Food Safety and Standards Act, 2006.
Since then, the regulator has significantly expanded inspections and surveillance. Recent enforcement actions include:
FSSAI has also issued notices to quick-commerce platforms over complaints of expired and spoiled food products being delivered to consumers.
Made by clarifying butter obtained from cow's milk, ghee is a staple in Indian kitchens and contains approximately 130 calories and 15 grams of fat per tablespoon. It is also a rich source of vitamins A, D, E and K, along with antioxidants.
However, because ghee is high in saturated fat, excessive consumption may raise LDL ("bad") cholesterol levels in some individuals and increase the risk of cardiovascular disease.
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Health experts advise people with certain medical conditions to consume ghee cautiously or avoid it altogether.
These include people with:
Doctors generally recommend limiting intake to no more than two teaspoons a day, unless advised otherwise by a healthcare professional.
Food adulteration involves the deliberate addition of inferior or harmful substances to food products, compromising their quality and safety.
According to a 2024 study published in SAGE Open Medicine, consuming adulterated food may increase the risk of:
The study notes that children, pregnant women and older adults are particularly vulnerable to the harmful effects of adulterated food.
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India has approved its first plant-based Vitamin D3 (cholecalciferol) ingredient, a move that could expand options for food fortification and dietary supplements while addressing the country's widespread Vitamin D deficiency.
The Food Safety and Standards Authority of India (FSSAI) has cleared VITADEE Green, developed by Fermenta Biotech,for use in health supplements, nutraceuticals and food products.
The company stated that the ingredient is produced using an India-patented process and offers a sustainable, scalable and vegetarian-friendly source of Vitamin D3.
The approval allows Indian manufacturers to incorporate the ingredient into fortified foods, beverages and dietary supplements.
It is particularly significant for vegetarians and vegans, who have traditionally had limited access to Vitamin D3 because most supplements are derived from lanolin, a by-product of sheep's wool.
The approval also supports India's broader efforts to improve nutrition through food fortification, an area where experts say Vitamin D remains a major gap.
Studies suggest a large proportion of Indians have inadequate Vitamin D levels despite abundant sunlight, largely due to urban lifestyles, limited outdoor exposure and reduced sun exposure.
"Vitamin D deficiency remains a widespread public health concern in India, and the demand for sustainable nutrition continues to grow rapidly. The FSSAI approval allows us to bring VITADEE Green directly to Indian food fortification and nutraceutical manufacturers, helping bridge the nutrition gap for the country's large population," said Prashant Nagre, Managing Director, Fermenta Biotech.
For India's large vegetarian population, the approval also brings a domestically manufactured, regulatory-approved plant-source Vitamin D3 to the market.
Vitamin D3, often called the "sunshine vitamin," is produced by the body when the skin is exposed to sunlight.
It helps the body absorb calcium, maintain healthy bones and teeth, and lowers the risk of fractures. In children, severe deficiency can lead to rickets, while in adults it increases the risk of osteoporosis, muscle weakness and falls.
Beyond bone health, Vitamin D3 also supports immune function. Research suggests low Vitamin D levels may be associated with increased susceptibility to infections and higher levels of inflammation.
Despite abundant sunshine, Vitamin D deficiency is common across India. Experts attribute this to long hours spent indoors, limited outdoor activity, sunscreen use, ageing and diets naturally low in Vitamin D.
Low Vitamin D levels can lead to weak bones, muscle weakness and an increased risk of fractures. In children, severe deficiency can cause rickets, while inadequate levels have also been linked to poorer immune function.
"Vitamin D deficiency remains a widespread public health concern in India, and the demand for sustainable nutrition continues to grow rapidly," said Prashant Nagre, Managing Director of Fermenta Biotech.
Doctors say no—not in terms of effectiveness.
Dr. Murtaza S. Bagwala, Head of Emergency Medical Services at Saifee Hospital, Mumbai, told HealthandMe that current evidence shows plant-based Vitamin D3 raises Vitamin D levels just as effectively as conventional supplements.
"Based on current science, plant-based Vitamin D3 is comparable to conventional Vitamin D3 supplements. For most people, it is a good alternative if they prefer a plant-based product," he said.
Dr. Sudhir Kumar, Neurologist at Apollo Hospitals, Hyderabad, explained that plant-derived Vitamin D3—typically sourced from lichen, algae or newer fermentation technologies—offers an animal-free option without compromising efficacy.
"It is good news for consumers who prefer vegan products, but both forms are equally effective. There is no medical reason for people to switch if they are already taking conventional Vitamin D3," he said in a post on X.
The experts said the key question is whether supplementation is needed, not whether the source is plant- or animal-derived.
"The source matters mainly for ethical, dietary or personal preference—not for efficacy," Dr. Sudhir said.
Dr. Bagwala cautioned against taking high-dose Vitamin D without medical advice, as excessive intake can raise calcium levels and increase the risk of kidney stones and other complications.
Doctors recommend that supplementation should be based on:
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One extra serving of leafy greens like kale and spinach may be good for your lungs and help you breathe better, according to a study. The secret? It is the vitamin K1 found in leafy green vegetables.
Researchers from Edith Cowan University (ECU) tracked more than 179,000 adults over a decade and found that people who eat more vitamin K1-rich foods such as leafy green vegetables may lower their risk of chronic lung disease and boost lung function.
“We found that people who ate more vitamin K1-rich green vegetables had better lung function and were less likely to develop COPD,” ECU researcher Chengfeng Li said.
“Just one extra serve of leafy greens like kale, about one and a half to two cups a day, is an achievable way to boost your vitamin K1 intake,” Li added.
The findings suggest that adding more greens to your plate could help keep your lungs in better shape as you age.
The study found that those with the highest intake of vitamin K1 had about a 16 per cent lower risk of COPD compared to those eating the least.
They also had better lung performance, meaning their lungs could hold and move more air, a key sign of good respiratory health.
“Vitamin K likely activates a protein that protects the lungs’ elastic fibers - the tiny structures that let your lungs expand and contract,” Associate Professor Marc Sim said.
“When these fibers break down, breathing becomes harder over time. This nutrient may help keep lung tissue flexible and prevent damage,” Sim added.
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The second type, vitamin K2, showed no benefit for COPD risk, though it was linked to somewhat better lung function at moderate intakes.
The researchers think the same protective mechanism probably applies to vitamin K2, but any benefit may be masked by what it's eaten alongside.
K1-rich leafy greens, by contrast, come with their own bonus nutrients like fiber and antioxidants that may boost the effect, while K2's main sources, including processed and red meat, are linked to poorer health outcomes.
The study also found no link between vitamin K and asthma, suggesting vitamin K may be more relevant for long-term lung damage rather than allergic conditions.
While the boost from greens appears favorable, researchers are clear on one thing: it won’t cancel out smoking.
“The biggest thing you can do for your lungs is to quit smoking and reduce your exposure to environmental pollution,” Li said.
“But a healthy diet may still play a supporting role by counteracting some of the damage caused by these harmful factors.”
“Eating more leafy greens is a simple step that could help support lung health over time.”
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The World Health Organization data shows that chronic obstructive pulmonary disease (COPD) remains the fourth leading cause of death worldwide. The condition was responsible for an estimated 3.5 million deaths in 2021, according to the latest available global data.
COPD is a common and serious lung disease, and the WHO noted that smoking, indoor and outdoor pollution, and harmful inhalants are among its most significant triggers.
If your breathing feels effortless, steady, and natural, so much so that you barely notice it, your lungs are likely in good shape. To maintain this good lung health, it is essential to:
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