A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.

The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.

The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.

Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:

"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.

Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.

"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.

Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."

One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:

"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."

Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.

These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.

Link Between Metabolism and Bipolar Disorder

Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.

One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.

What Is a Ketogenic Diet?

The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.

First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.

There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.

Ultra-processed foods (UPFs), typically high in salt, sugar, and unhealthy fats, have long been associated with obesity, diabetes, hypertension, and other chronic diseases.

Now, new research suggests that the vast majority of foods marketed for toddlers in the US fall into this category. A study led by the University of Texas at Austin found that more than 80% of toddler foods sold in US grocery stores are ultra-processed, while nearly half fail to meet at least one nutrient standard set by the World Health Organization (WHO) for commercial foods intended for children aged 6 to 36 months.

Majority Of Toddler Foods Are Ultra-Processed

Also read: Can Your Child’s Diet Shape Future Diabetes Risk? Study Links Ultra-Processed Foods To Early Insulin Responses

Researchers analyzed 2,783 toddler food products sold across 21 grocery stores in Texas. Using the Nova classification system, they found that 81% of products were ultra-processed, while 49% failed to meet at least one WHO nutrient standard.

Among the products analyzed:

• 81% were classified as ultra-processed.
• 17% exceeded WHO recommendations for sugar.
• 25% exceeded recommended sodium levels.
• 11% exceeded recommended fat levels.
• 12% exceeded recommended energy density.

Products that exceeded WHO recommendations included:

• Fruit pouches (high in sugar)
• Oat bars (high in sugar and calories)
• Mac and cheese (high in sodium and fat)
• Turkey sticks (high in sodium and fat)
• Cheese puffs (high in calories)
• Peanut butter puffs (high in sodium, fat, and calories)

“Many parents may assume that products sold on the baby/toddler food aisles of their grocery stores have to meet certain nutrient standards. Our findings highlight that half of the toddler foods available in local grocery stores do not,” said Erin A. Hudson, a University of Texas at Austin graduate student and science policy fellow with the American Society for Nutrition.

Hudson urged parents "to be vigilant in checking labels and ingredients to determine the nutrient content and processing level of products for their toddlers".

Read More: 'Let's Fix Our Food': India Launches New Policy To Fight Childhood Obesity, Boost Nutrition

Why Is This Concerning?

The toddler years are a crucial period for developing lifelong eating habits and taste preferences. Diets high in added sugars and ultra-processed foods during early childhood may increase the risk of obesity, diabetes, cardiovascular disease, and other chronic illnesses later in life.

The researchers found that ultra-processed toddler foods were significantly more likely to be high in sugar than less-processed alternatives. Excess sugar intake in young children has been consistently linked to poor health outcomes, including obesity and metabolic disorders.

The findings come as the US Food and Drug Administration (FDA) is considering new guidelines for front-of-package nutrition labels, healthy claims and marketing of food products to children. The US currently does not require warning labels on any food products that are high in sugar, sodium or calories.

What Are Ultra-Processed Foods?

Ultra-processed foods (UPFs) are industrially manufactured products made with ingredients and additives rarely used in home cooking, including preservatives, emulsifiers, artificial sweeteners, colorants, flavor enhancers, and hydrogenated oils. They are generally high in refined carbohydrates, added sugars, unhealthy fats, and sodium, while being low in fiber and other essential nutrients.

Research suggests that diets high in UPFs may promote chronic inflammation, disrupt the gut microbiome, and impair insulin regulation over time, potentially increasing the risk of obesity, type 2 diabetes, cardiovascular disease, and other chronic illnesses from an early age.

The monsoon season offers relief from the heat but also creates the perfect environment for bacteria, viruses, and fungi to multiply. As a result, stomach infections, food poisoning, diarrhea, and indigestion become more common.

Thus, fermented foods act as a natural probiotic to keep the gut healthy during the rainy season. They also support digestion, improve nutrient absorption, and may reduce the risk of digestive problems during the rainy season. However, the humidity can spoil the food.

HealthandMe spoke to experts who stressed good hygiene and freshly cooked meals. They also called for foods to be prepared

and stored safely to prevent contamination.

Common probiotic-rich homemade foods include:

• Curd (dahi)
• Buttermilk (chaas)
• Fermented rice (panta bhat)
• Idli and dosa batter
• Kanji
• Hygienically prepared homemade pickles

Why Fermented Foods Are Good During Monsoon

The experts said that homemade fermented foods naturally contain beneficial bacteria (probiotics) that help maintain a healthy gut microbiome.

"Monsoon brings a natural dip in immunity, and gut health takes centre stage in staying resilient through the season. Fermented foods are one of the simplest ways to introduce live beneficial bacteria that aid digestion and strengthen the body's natural defence mechanisms," Dr. Eileen Canday, Head of Nutrition & Dietetics at Sir H. N. Reliance Foundation Hospital, Mumbai, told HealthandMe.

Riya Oswal, Clinical Nutritionist at Ruby Hall Clinic, said pairing good hygiene with probiotic-rich fermented foods can help support gut health and strengthen the body's natural defenses.

Why Fermented Foods Can Be Risky During Monsoon

Despite their benefits, fermented foods can become unsafe if they are not prepared or stored properly.

"The higher humidity and fluctuating temperatures during the monsoon create favorable conditions for harmful microorganisms if fermentation is not properly controlled," Dt. Deepali Sharma, Clinical Nutritionist at CK Birla Hospital, Delhi, told HealthandMe.

How to Prepare Fermented Foods Safely

Food safety becomes especially important during the rainy season. The experts recommended to:

• Wash hands thoroughly before preparing food.
• Use clean, sterilized utensils.
• Prepare foods with safe drinking (potable) water.
• Use fresh ingredients.
• Follow the recommended fermentation time and avoid over-fermentation in humid weather.
• Cover food properly while it ferments.
• Refrigerate fermented foods promptly after fermentation.
• Store them in clean, airtight containers.
• Consume them within the recommended storage period.

When Should You Throw Fermented Food Away?

Do not consume homemade fermented foods if they show signs of spoilage. Discard them if you notice:

• An unusual or foul smell
• Mold growth
• Discoloration
• A slimy texture
• An excessively sour taste

"Any fermented item that has been maintained at a temperature beyond the normal room temperature for too long must also be avoided, since it might carry dangerous microbes, even if everything seems fine at first glance," she said.

Who Should Be Extra Careful?

While fermented foods are generally safe for healthy individuals, some people should consult a doctor before consuming homemade fermented products, Oswal told HealthandMe.

These include:

• People with weakened immunity
• Patients undergoing chemotherapy
• Organ transplant recipients
• Those receiving immunosuppressive therapy
• People with serious chronic illnesses
• Individuals with uncontrolled gastrointestinal diseases

Sharma added that infants, older adults with reduced immunity, and pregnant women should consume only freshly prepared and properly stored fermented foods during the monsoon to minimize the risk of infection.

The Indian Council of Medical Research–National Institute of Nutrition (ICMR-NIN) has launched a new policy document aimed at tackling childhood obesity and promoting healthier diets and food environments for children and adolescents in India.

Released under the multi-institutional 'Let's Fix Our Food' (LFOF) consortium, which was launched in 2022, the policy comes as India faces a growing burden of obesity and diet-related non-communicable diseases (NCDs), including diabetes, hypertension, cancer and respiratory illnesses.

The document outlines evidence-based recommendations to improve food environments and encourage healthier dietary habits among children and adolescents.

"Evidence-based, multisectoral policy action is essential to create healthier food environments for children and adolescents. Collaborative initiatives such as the Let's Fix Our Food Consortium are important for addressing the growing burden of overweight, obesity and diet-related non-communicable diseases in India," said Dr. M. Srinivas, Member (Health), NITI Aayog.

What Does The Policy Recommend?

The policy outlines recommendations across several areas, including:

• Healthy school food environments
• Nutrition literacy
• Front-of-pack nutrition labelling
• Regulation of unhealthy food marketing to children
• Taxation of foods high in fat, salt and sugar (HFSS)
• Healthier dietary fats
• Salt reduction
• Low-sodium salt substitutes
• Social and behavior change communication
• Youth engagement
• Fiscal measures to promote healthier diets.

India's Growing Obesity, Malnutrition Burden

The policy highlights India's growing double burden of malnutrition.

According to the National Family Health Survey-6 (NFHS-6) fact sheets for 2023–24, the prevalence of overweight children under five has increased to 3.4%, up from 2.1% in NFHS-4 and 1.3% in the previous survey.

The survey also found that although stunting among children under five has declined to 29.3%, acute malnutrition (wasting) remains unchanged at 5.2%, and only 15% of young children receive an adequate diet.

"Malnutrition is no longer only about undernutrition. Rising obesity, driven by unhealthy diets, challenges healthy growth among children and adolescents," said Marie-Claude Desilets, Chief of Nutrition, UNICEF India.

Key Recommendations

The Let's Fix Our Food Consortium was established to generate evidence and drive policy action for healthier food environments, particularly for children and adolescents. Based on multidisciplinary research and expert consultations, the policy recommends:

Stricter Advertising Rules

• Enforce legal restrictions on marketing HFSS foods to children and adolescents.
• Ban misleading health claims and deceptive advertising across all media.

Front-of-Pack Nutrition Labels

• Introduce mandatory, easy-to-read nutrition labels on packaged foods.
• Help consumers quickly identify products high in fat, salt and sugar.

Healthier School Food Environments

• Restrict junk food in and around schools.
• Ensure affordable, healthy food options and monitor school food environments using NEAT-S.

Tax Junk Food

• Levy taxes on HFSS foods and sugar-sweetened beverages to discourage consumption.
• Use fiscal measures to make healthier foods more affordable.

Strengthen National Programs

• Integrate these measures into initiatives such as the Ayushman Bharat School Health and Wellness Programme to promote better nutrition and physical activity.

New Tools to Support Healthy Eating

The consortium also launched practical tools to help schools and adolescents make healthier food choices.

• Nutrition Environment Assessment Toolkit for Schools (NEAT-S): A framework to help schools assess and improve their food environments by promoting healthier canteens.
• Digital Literacy Modules: An interactive e-learning platform and comic books developed by ICMR-NIN to help adolescents understand food labels and reduce their intake of excess sodium and unhealthy fats.

The initiative is supported by several national and international organizations, including UNICEF India, the Global Health Advocacy Incubator (GHAI), the Public Health Foundation of India (PHFI), the World Health Organization (WHO), the Food Safety and Standards Authority of India (FSSAI), and other partners.