A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.

The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.

The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.

Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:

"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.

Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.

"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.

Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."

One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:

"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."

Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.

These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.

Link Between Metabolism and Bipolar Disorder

Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.

One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.

What Is a Ketogenic Diet?

The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.

First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.

There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.

Collagen is essential for maintaining firm skin, prevent premature aging and regulates cell proliferation. While it is usually found in animal sources, many fruits and super foods acts rich sources.

Why Does Collagen Fall as You Age?

Here are natural collagen rich superfoods, you can consume:

Vitamin C Rich Fruits Guava, Amla, and kiwi help stimulate collagen supporting skin repair and hydration.

Strawberries are rich in polyphenols, reducing oxidative stress, while oranges provide hydration and vitamin for rebuilding the skin. These fruits are catalysts essential for youthful and resilient skin.

Meats

Leafy Greens and Nuts

Supplements

Collagen is the perfect ingredient for glowing skin and it is all over the internet–coffee, Collagen is added to coffee by mixing peptides which dissolve easily in hot liquid and powders that give comparatively quicker results. Type 1 Collagen is usually considered the best for skin.

Tiny but mighty, eating blueberries not only gives you a sweet taste but also can be extremely beneficial for your entire body.

Extremely rich in antioxidants called anthocyanins, they help with slowing down brain aging. Along with this, the fruit also helps regulates blood pressure and cholesterol levels, overall improving cardiovascular health.

Although they might sound beneficial, they are pricey and inaccessible to a majority of the public.

However, experts have now revealed that guava can provide the body with more benefits than blueberries at half the price.

Why Is Guava Better Than Blueberries?Guavas are living proof that appearances are deceptive. Packed with nearly five times more Vitamin C (about 228mg) and loaded with digestive fibers, this winter fruit is perfectly suited for everyday snacking.

According to Healthline, a single guava can fulfill 12 percent of your recommended daily intake of fiber. A 2025 overview by PubMed also shows that guava leaves have been researched for managing blood sugar levels.

Guavas contain soluble fibers which slow down the digestion and absorption of sugars, preventing sudden spikes in glucose levels. Previous research also shows that regular consumption can help improve insulin sensitivity and lipid profiles, benefiting metabolic health.

With significantly higher Vitamin C content than blueberries, this fruit supports collagen production and gives you brighter skin and protection against premature aging.

Which Other Fruits Are Rich in Antioxidants?

While cranberries support urinary tract health by preventing bacterial adhesion and reducing inflammation, strawberries are rich in Vitamin C and folate and help with blood sugar regulation which can help stabilize glucose levels.

After all the environmental damage and aging that you have caused your skin, it deserves the utmost care and protection to rebuild and glow.

While blueberries have been linked to improving skin texture, goji berries are far rich in flavonoids that can neutralize free radicals, boost collagen and protect against UV damage.

Blackberries and raspberries are excellent sources that reduce oxidative stress and inflammation.

Experts recommend incorporating a mix of these fruits in your diet to help repair your DNA, reduce inflammation and prevent chronic conditions.

If you drink 14 drinks per week, the American Cancer Society's peer-reviewed journal Cancer, noted that you have a 25% higher risk of developing colorectal cancer. This also means that you have a 95% higher risk of developing rectal cancer as compared to those who drink an average of one drink per week.

Moderate alcohol intake is measured as seven or less drinks per week, which is associated with a lower risk. However, experts have time and again stressed that there is no safe limit of drinking.

"While the data on former drinkers were sparse, we were encouraged to see that their risk may return to that of the light drinkers,” co–senior author Erikka Loftfield of the National Institutes of Health's National Cancer Institute said in a news release.

What the Study Found

The findings come from an analysis of U.S. adults who took part in the National Cancer Institute’s Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Researchers tracked 88,092 participants over a 20 year period and identified 1,679 cases of colorectal cancer during that time.

The data showed a clear pattern. Higher lifetime alcohol consumption was linked to a higher risk of colorectal cancer, with the strongest association seen for rectal cancer. However, the study also offered encouraging news. People who stopped drinking saw their risk decline, highlighting that lifestyle changes can still make a difference later in life.

Read: Drinking Alcohol Could Damage Your DNA, Not Just Your Liver Or Heart

Colorectal Cancer Is Rising in Younger Adults

These findings come at a time of growing concern about colorectal cancer rates, especially among younger people. Earlier this month, the American Cancer Society reported that colorectal cancer has become the leading cause of cancer-related deaths among people under 50 in the United States.

Dr. Ahmedin Jemal, senior author of the report and senior vice president of surveillance, prevention and health services research at the American Cancer Society, said the trend is alarming. He noted that the speed at which colorectal cancer rates have risen among younger adults means it can no longer be considered a disease that only affects older people.

Also Read: Diljit Dosanjh Swears By This Green Juice to Power His 4am to 9pm Routine

Changing Guidance on Alcohol Consumption

Federal health guidance around alcohol has also shifted. Instead of specifying how many drinks are considered safe, the latest dietary guidelines advise Americans to drink less overall. People with certain health conditions are encouraged to avoid alcohol entirely.

Christopher Kahler, director of the Center for Alcohol and Addiction Studies at Brown University, has previously explained that no amount of drinking is completely risk-free. According to him, health risks increase with higher consumption, which is why current guidelines focus on reducing intake rather than defining a safe threshold.

What This Means for Individuals

Taken together, the research reinforces a simple message. Heavy drinking raises cancer risk, drinking less is better for health, and stopping alcohol use can help lower the chances of developing colorectal cancer. With rates rising in younger adults, experts say awareness and prevention efforts are more important than ever.