A revolutionary study published in BJPsych Open has revealed compelling evidence that a ketogenic diet can have a major impact on mental and physical well-being in bipolar disorder patients. The study, conducted by Dr. Iain Campbell, PhD, Baszucki Metabolic Psychiatry Research Fellow at the University of Edinburgh, investigates how a metabolic-based intervention might represent an exciting new strategy for treating this serious mental illness.

The research is the first in Europe to use neuroimaging methods, namely magnetic resonance spectroscopy (MRS), to investigate changes in brain metabolism in people with bipolar disorder after a ketogenic diet. The imaging findings revealed decreases in excitatory neurotransmitters, which are normally increased in bipolar disorder. This indicates that the ketogenic diet can stabilize brain activity, possibly reducing mood swings and other symptoms of the condition.

The trial involved 27 participants diagnosed with bipolar disorder, 20 of whom successfully completed the 6-8 week program. A staggering 91% of these individuals maintained ketosis, the metabolic state where the body primarily burns fat for energy instead of carbohydrates. Those who provided consistent daily ketone and mental health assessments reported notable improvements in mood, energy levels, anxiety, and impulsivity.

Dr. Campbell, who personally adheres to a ketogenic diet himself in order to treat symptoms of bipolar disorder, discussed the importance of these results:

"We saw indicators of diminished excitotoxicity in the brain regions most implicated in bipolar disorder. These findings are consistent with the metabolic overdrive hypothesis that postulates energy dysregulation within the brain as central to the disorder. Treating the dysregulation by means of a ketogenic diet could be a game-changer in treatment-resistant patients.

Aside from the scientific evidence, personal accounts of study participants underscore the life-altering effect of a ketogenic diet.

"Quite literally, for the first time in years, I felt like my brain was finally fueled correctly," explained a participant.

Another participant called the diet "a lifeline, restoring my energy and sense of hope. I felt like I was finally healing my mind, not just coping with my bipolar symptoms."

One of the very vivid accounts described the impact of ketosis in terms of a relaxing mental atmosphere:

"Applying a ketogenic diet is akin to giving my mind a nice warm bath. The edginess disappears. I am more calm, more clear, and my brain function is restored again."

Aside from the psychological benefits of the study, the ketogenic diet was also seen to have beneficial effects on participants' physical health. Nineteen out of the 20 trial completers lost a total of 9.3 pounds (4.2 kg) on average and showed improvements in body mass index (BMI) and blood pressure.

These results are noteworthy in that numerous treatments for bipolar disorder, such as mood stabilizers and antipsychotic medications, have been linked to metabolic side effects of weight gain and risk of cardiovascular disease. In contributing to the reduction of such risks, a ketogenic diet may provide a double dividend for patients with bipolar disorder.

Link Between Metabolism and Bipolar Disorder

Although the ketogenic diet has previously been known largely for its utility in treating epilepsy that is treatment-resistant, it is a somewhat new area to explore in conditions of psychiatry such as in bipolar disorder. It has come to be known that metabolic imbalance is an underlying factor in causing psychiatric disorders as energy production deficiencies have been recognized to contribute towards neural excitability and mood disruption.

One of the important findings of the study is that people with bipolar disorder tend to have sodium levels higher than usual within their cells. Lithium, a standard mood stabilizer, acts partly by reducing these sodium levels. The ketogenic diet seems to do the same thing, offering a metabolic explanation for its beneficial effect on mood stabilization.

What Is a Ketogenic Diet?

The ketogenic diet is a high-fat, low-carb diet that changes the body's main source of energy from glucose to ketones. As carbohydrate consumption is significantly decreased, the liver breaks down fats into ketones, which can be used as a substitute fuel by the brain and body.

First developed in the 1920s as a therapy for epilepsy, the ketogenic diet has been researched for its therapeutic applications in a variety of neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and most recently, bipolar disorder.

There's a critical need for bigger replication studies and well-designed randomized clinical trials to follow up on these findings," added Dr. Campbell. "Our findings indicate that a ketogenic diet may be a useful adjunctive treatment for bipolar disorder, bringing new promise to patients who have difficulty with standard therapies.

Diljit Dosanjh posted a reel dated December 11, where he flaunted his workout plan which starts at 4am and his day ends at 9pmDiljit Dosanjh Swears by This Green Juice to Power His 4am to 9am Workout. His secret to a long day is his 'green juice'. In the video itself, the 42-year-old actor and singer shared that he makes a green juice.

What Is Diljit Dosanjh's Green Juice?

He had shared once on his story in 2021 that he mixes neem and amla along with water for his green juice. The juice works best when consumed on an empty stomach. Why does this juice work?

Neem is loaded with benefits, and same is the case with amla. Neem is known for improving cardiovascular health, eyesight, liver health and the overall immune system. Amla on the hand contains nutrients like vitamin A, pyridoxine, riboflavin and minerals like sodium, potassium, carotene, calcium, copper, zinc, phosphorus, manganese, magnesium, and iron. Amla is also known to help with digestion and increase production of red blood cell.

What Are The Benefits Of Amla And Neem?

Amla or Indian gooseberry helps in diabetes control as they have soluble fiber in it and it dissolves quickly in the body. This also helps to slow down the rate at which your body absorbs sugar. Furthermore, it aids with digestion, and the vitamin A content in it helps with eye health. Amla is also rich in vitamin C, which helps in improving immunity and its antibacterial and anti-inflammatory properties helps furthermore with boosting health.

Neem, or scientifically called Azadirachta Indica contains chemicals that could help with diabetes control by reducing blood sugar levels, heal ulcers in the digestive tract, prevent pregnancy, kill bacteria, and prevent plaque from forming in the mouth.

What Does Diljit Dosanjh's Day Look Like?

He wakes up at 4am and his day begins with energy and powerhouse performances. His fitness regime includes a mix of cardio and weight training.

His day starts with cardio which includes:

Climbing Stairs

• Stand at the bottom of the staircase with your back straight.
• Step up with one foot, then bring the other foot up to the same step.
• Continue climbing at a steady pace, using the handrail if needed for balance.
• Walk back down carefully, keeping your steps controlled.
• Repeat for several rounds or for a set time.

Push Ups

• Start in a plank position with your hands placed slightly wider than shoulder-width.
• Keep your body in a straight line from head to heels.
• Bend your elbows and lower your chest toward the floor.
• Push through your palms to straighten your arms and return to the starting position.
• Repeat for the desired number of reps. Beginners can keep their knees on the floor.

Jumping Jacks

• Stand straight with your feet together and arms by your sides.
• Jump up, spreading your legs while raising your arms overhead.
• Jump again to bring your feet back together and arms down.
• Maintain a steady rhythm and breathe normally.
• Continue for a set number of reps or time.

His weight training includes:

Chest flys with dumbbells

• Lie flat on a bench or the floor, holding a dumbbell in each hand.
• Extend your arms above your chest with palms facing each other.
• Keep a slight bend in your elbows throughout the movement.
• Slowly lower your arms out to the sides until you feel a stretch in your chest.
• Bring the dumbbells back together above your chest in a controlled motion.
• Repeat for the desired number of reps.

Dumbbell overhead extensions

• Stand or sit upright, holding one dumbbell with both hands.
• Raise the dumbbell overhead, arms fully extended.
• Keep your elbows close to your ears.
• Slowly bend your elbows to lower the dumbbell behind your head.
• Extend your arms to lift the dumbbell back to the starting position.
• Repeat while keeping your core tight and back straight.

His workout regime ends with light yoga, with cobra pose.

Kennedy Jr. recently revealed how he lost 20 pounds in 20 days on a highly restrictive diet focused completely on meats and fermented foods.

In an interview with USA Today’s “The Excerpt” podcast, the US Health and Human Services Secretary revealed that he followed the diet the whole day. “That may not be right for other people, but I lost 40 percent of my visceral fat within a month”. His eating habits have been highlighted before; previous interviews revealed he ate a steak along with fermented vegetables for breakfast.

However, is carnivorous die ideal for weight loss and are there any major concerns related to solely living on different kinds of meats?

Is A Carnivorous Diet Health?

A "carnivore" diet contains only animal products such as meat, eggs, and dairy. Kennedy Jr. also mentioned fermented foods, which include sauerkraut, yogurt, or miso, that are made using natural bacteria. While Kennedy Jr. claimed he lost 20 pounds in 20 days and felt more mentally clear, he also admitted some of it could be a ‘placebo effect.’

The leader of the MAHA movement reportedly eats steak and fermented vegetables for breakfast and even asks his wife, Cheryl Hines, to carry bags of sauerkraut in her purse when they go out to dinner, according to an interview by the CUT.

However, according to the British Heart Foundation, while some people use the carnivore diet to lose weight quickly, health experts warn that it could cause serious long-term damage to your body.

Does A Carnivorous Diet Aid In Weight Loss?

The carnivore diet works on the principle of ketosis, where the body burns fat for fuel because there are no carbs available. While you might lose weight at first, experts say this is likely because protein makes you feel full, so you naturally eat less. Also because you’ve cut out high-calorie snacks like cake, chips, and alcohol.

However, because the diet is so restrictive, most people find it impossible to stick to for very long. While the all-meat part of his diet is controversial, experts say the fermented foods he eats do have proven benefits.

How Does A Carnivorous Diet Affect Our Health?

The carnivore diet is heavy in red meat and dairy, which are packed with saturated fats. Consuming too much of these fats can lead to:

High Cholesterol

This increases your risk of heart attacks and strokes, as the bad cholesterol or LDL can block arteries and restrict blood flow from organs

High Blood Pressure

Many processed meats (like bacon) are high in salt, which strains your heart. When your salt consumption is high, it causes water retention, which puts pressure on your blood vessel walls, which eventually weakens them.

Kidney Stress

Eating massive amounts of protein forces your kidneys to work much harder to process the waste.

Which can lead to kidney stones, according to National Kidney Foundation.

Kennedy’s diet is much more extreme than the official advice he helped create. He was quick

However, Kennedy Jr.’s personal diet plan is much stricter than the one he helped create for millions of Americans while in office. The official was quick to inform viewers that he is not trying to be a ‘role model’ for everyone, noting that what works for him might not be right for others.

Snacking on grapes could offer surprising protection against heart attacks and strokes, researchers say. The fruit, often labelled a superfood, contains natural compounds that support gut health and help bring down cholesterol levels, both of which play a role in heart disease.

Researchers found that even a short-term change made a difference, especially for people whose diets were low in vegetables and fibre.

Eating Grapes May Lower Heart Attack and Stroke Risk, Study Finds

As per Express UK,In the study, participants saw health improvements after just four weeks of eating grapes daily. The simple dietary shift was linked to a lower risk of cardiovascular disease, which remains the leading cause of death worldwide.

Grapes are rich in antioxidants known to calm inflammation, a key driver of heart problems.

How Grapes Affect Cholesterol and Gut Health

Professor Zhaoping Li of the University of California, Los Angeles, who led the research, said grapes improved the diversity of gut bacteria while also reducing cholesterol levels.

The study followed adults aged 21 to 55 who ate the equivalent of about 40 grapes, or two servings, each day. Their usual diets were low in fibre and plant compounds called polyphenols.

Within a month, researchers saw a clear increase in microbiome diversity. This community of trillions of bacteria plays a central role in digestion, immunity, and overall health.

Drop In ‘Bad’ Cholesterol And Harmful Fats

Participants recorded nearly an eight per cent reduction in LDL cholesterol, often described as the “bad” kind. Levels of bile acids, which fuel harmful fats in the body, fell by more than 40 per cent.

These fats are linked to the formation of clots that can block blood vessels and cut off blood supply to the heart or brain.

Rise in Beneficial Gut Bacteria

One of the most notable changes was an increase in Akkermansia, a beneficial bacterium known to help burn sugar and cholesterol and strengthen the gut lining.

Professor Li said the findings were encouraging, as a healthy gut is increasingly recognised as essential to good overall health.

Why Researchers Call Grapes A Superfood

Professor Li said the study adds to growing evidence of grapes’ heart health benefits, particularly their role in lowering cholesterol. Grapes provide a rich mix of fibre and polyphenols, which appear to influence how the body processes fats.

The findings, published in the journal Nutrients, may help shape future research into diet and disease prevention.

Previous research has linked grapes to a range of health benefits, from helping manage weight gain in middle age to improving libido.

In another study, researchers found grapes may help counter the effects of processed foods high in fats and sugars.

In experiments on mice fed a high-fat Western-style diet, those given a daily grape supplement showed less fatty liver disease and lived longer than those that did not.

Dr John Pezzuto of Western New England University said the results suggest grapes may influence how genes linked to metabolism and ageing behave. The changes observed in mice could equate to several additional years of life in humans.

Researchers also found improvements in brain function. Mice given grape supplements showed better behaviour and cognition, suggesting potential protective effects against conditions such as Alzheimer’s disease.

Grapes and Metabolism

A separate study found grapes may also boost metabolism, helping the body burn calories more efficiently. This could explain their protective role against non-alcoholic fatty liver disease, which is strongly linked to poor diet.

Dr Pezzuto said long-term grape consumption appeared to reduce oxidative damage, improve fat metabolism, and support longevity, even alongside a high-fat diet.

Heart disease kills an estimated 17 million people globally each year and more than 160,000 in the UK alone. While grapes are not a cure, researchers say the evidence suggests they can play a meaningful role as part of a balanced diet.

The findings were published across several journals, including Foods, Antioxidants, and Food & Nutrition, adding to growing interest in how everyday foods influence long-term health.