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Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that affects millions of people, both children and adults. The key characteristics are hyperactivity, impulsivity, and inattention. Because of many obstacles, researchers have been searching for other therapies—inclining to include diet intervention to control the symptoms of ADHD more effectively. One interesting area of research is that for chili peppers! Yes, you read it correctly, scientists are studying the effects of chilli peppers in order to help ease symptoms of ADHD through their action on gut microbiota and the gut-brain axis.
The gut-brain axis (GBA) is a two-way communication system that connects the gastrointestinal tract with the central nervous system. It has significant roles in brain function, emotional control, and cognitive processes. The most recent research indicates that gut microbiota- bacteria living in the digestive system can potentially affect ADHD by impacting the production of neurotransmitters and brain structure.
People with ADHD tend to have reduced levels of healthy gut bacteria, including Lactobacillus, and a less diverse gut microbiota. This imbalance can contribute to greater neuroinflammation and oxidative stress, both of which are involved in ADHD pathology.
Gut microbiota also control the production of dopamine and serotonin, two neurotransmitters critical for attention, impulse control, and emotional stability.
Chili peppers have bioactive molecules, such as capsaicin, vitamin C, and polyunsaturated fatty acids (PUFAs), that could affect symptoms of ADHD through modulation of the gut microbiota and neurotransmitter concentration.
Capsaicin, the phytochemical in chili peppers, has been found to modulate neurotransmitter levels. Experiments with animals reveal that capsaicin boosts the levels of serotonin and dopamine in the brain, which has the potential to enhance attention and impulse control.
Additionally, capsaicin has been shown to inhibit neuroinflammation and oxidative stress, both of which are associated with ADHD pathology. Through the reduction of these variables, capsaicin could help to decrease some ADHD symptoms. While animal models offer promising information, human studies are needed to ascertain if capsaicin supplementation can produce a concrete effect on ADHD symptoms.
Chili peppers are a rich source of vitamin C, a potent antioxidant that enhances immune function, neurotransmitter production, and iron absorption. New evidence indicates that vitamin C can also increase the prevalence of helpful microbes such as Lachnospiraceae in the gut microbiota. Gut microbial balance has been implicated in neurodevelopmental diseases such as ADHD, and vitamin C's activity in regulating gut microbes could potentially be used as a therapy.
Moreover, vitamin C also decreases brain inflammation, which tends to be higher in patients with ADHD.
Chili peppers are also rich in PUFAs, such as omega-3 and omega-6 fatty acids. Studies have established that patients with ADHD tend to have lower levels of omega-3 PUFAs, which are important for brain function, synaptic plasticity, and regulation of neurotransmitters. Omega-3 supplementation has been shown to enhance memory function and boost short-chain fatty acid (SCFA)-producing gut bacteria, which promote brain and gut health.
Given that PUFAs have anti-inflammatory properties and maintain cognitive function, their occurrence in chili peppers contributes to the accumulating data indicating dietary intervention may be effective in modulating ADHD symptoms.
Although chili peppers have bioactive substances that could affect the gut-brain axis and help alleviate ADHD symptoms, their impact is speculative until stricter human trials are carried out. Being a readily available food item, peppers can be used as a possible adjunct therapy, which can be added to conventional ADHD treatments. Peppers, however, cannot be used as a substitute for established medical therapies, including behavioral therapy and prescription drugs.
The developing connection between nutrition, gut microbiome, and ADHD has paved the way for exploring non-medication interventions. Chili peppers, rich in capsaicin, vitamin C, and PUFAs, represent a novel yet unproven method for modulating ADHD symptoms. While early research points towards a possible intervention by chili peppers in modulating neurotransmitter content and minimizing neuroinflammation, human studies are essential to validate the observations.
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Folklore has long suggested that a hot toddy, the warm alcoholic drink made with hot water, lemon juice, honey, and spirits such as whiskey, rum, or brandy, can ease a sore throat or help clear congestion caused by a winter cold. Many people swear by it. But what exactly is a hot toddy, and how does it work when you are dealing with cold and congestion?
Hot toddy is a popular winter drink, especially during colder months. It is a traditional mix of whiskey or rum, hot water, honey, lemon, and warming spices like cinnamon or cloves. The drink helps warm the body, offers comfort in chilly weather, and may support the body during seasonal illnesses such as colds and flu.
Each ingredient plays a role. Honey is known for its natural antibacterial properties, while lemon provides vitamin C to support immune health. Alcohol acts as a mild vasodilator, which helps improve blood flow, and spices aid digestion while easing congestion. Together, these elements make hot toddy a soothing, natural option for winter discomfort.
That said, moderation is key. One serving, or at most two, especially in the evening, may help with sleep, stress, congestion, sore throat, and general discomfort. Below are some potential health benefits of drinking a hot toddy during winter.
A hot toddy can feel deeply comforting when your throat is irritated during winter. The heat from the water, combined with honey, helps coat the throat and calm inflamed tissues. This can ease irritation caused by dry air or colds. Honey’s antibacterial qualities support healing, while lemon adds vitamin C to help the immune system. A small amount of whiskey or rum may further relax throat muscles, making coughing and swallowing less uncomfortable.
Winter often brings frequent infections, but a hot toddy may help strengthen the body’s natural defences. Vitamin C from lemon supports white blood cells that fight viruses common in colder months. Honey provides antioxidants and enzymes that assist overall immunity. The warmth of the drink increases circulation, helping immune cells move efficiently through the body. Spices such as cinnamon or ginger offer anti-inflammatory benefits that may reduce the risk of infection. Having this drink before bedtime can support the body during seasonal changes.
Blocked noses are a common winter complaint, often caused by cold air outside and dry heating indoors. The steam from a hot toddy can help loosen mucus in the sinuses and nasal passages. Lemon’s acidity may help break down phlegm, while alcohol slightly widens blood vessels, which can ease congestion. Slowly inhaling the vapour can help open airways and make breathing more comfortable.
Few things fight winter chills better than a warm drink. Hot toddy raises your core temperature, helping warmth spread through the body. Alcohol encourages better circulation, especially to hands and feet that often feel cold. Ingredients like ginger or cloves add a warming effect by gently increasing metabolic heat.
Winter stress, shorter days, and busy schedules can interfere with sleep. A hot toddy in moderation may help the body relax. Alcohol has a calming effect that can slow mental activity and ease restlessness. Honey may help stabilise blood sugar levels overnight, reducing sleep interruptions. The warmth of the drink also signals the body to wind down and prepare for rest.
There is no cure for the common cold. Most people manage symptoms through home remedies and over-the-counter medicines. Honey is known for its anti-inflammatory effects, and lemon contains antioxidants that support health. However, no scientific studies have directly proven that hot toddies treat colds.
That said, according to Medical News Today, many people believe that a hot toddy can help ease common cold symptoms, including:
While it may not cure a cold, a hot toddy can offer comfort and temporary relief during the winter months when used responsibly.
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A young man walked into a hospital with two worrying symptoms that had been bothering him for nearly two weeks. His eyes had turned yellow and his urine had grown unusually dark. These are classic warning signs of jaundice, often linked to liver trouble. Naturally, doctors began running tests.
He had already consulted two doctors before reaching out to The Liver Doc, @theliverdr on Instagram, Dr Cyriac Abby Phillips, hepatologist and clinician scientist, who shared this case study on his Instagram post. Blood tests for common causes of acute hepatitis came back negative. Viral markers were clear. Autoimmune conditions were ruled out. Scan after scan showed nothing definitive. Despite extensive investigations, no one could pinpoint the cause.
When he finally The LiverDoc, even his team found themselves stuck.
As Dr Philips later wrote in his post, the breakthrough came not from a scan or a lab report, but from a conversation. Almost as a last attempt, the team asked the patient a simple question. Had he changed anything recently in his diet?
The young man paused and then mentioned something that seemed harmless at first. He had started drinking coffee a few weeks earlier.
Coffee? That did not raise alarms immediately. As Dr Philips often points out in his posts, regular coffee is actually known to be protective for the liver. It does not cause jaundice.
But then came the detail that made everyone stop. It was not regular coffee. It was “Chinese coffee” given to him by his roommate.
When asked to show the product, the patient shared a photo. Dr Philips, a coffee lover himself, immediately realized this was not coffee at all. It was Chinese herbal coffee, specifically a product labelled as Jasmine Black Coffee, sold as an instant powder drink.
After what Dr Philips described as a “whodunit-style investigation,” the cause finally became clear. The young man had been drinking this herbal coffee for a week, about two to three cups a day, just before his symptoms began. Along with jaundice, he had severe itching of his hands and feet, another sign of liver injury.
True jasmine plants, commonly used for flavoring teas, are generally safe in small amounts. But as Dr Philips explained in his post, several toxic plants are also casually referred to as “jasmine.”
These include Night-blooming jasmine, Yellow jessamine, and Star jasmine, all of which can cause serious toxicity. Some contain compounds that behave like vitamin D in the body, leading to dangerous calcium overload. This can damage not just the liver, but also the heart and kidneys.
The biggest concern, according to Dr Philips, is that these herbal coffees and teas are largely unregulated. There is no reliable way for consumers to know which plant species or plant parts are actually used. Health claims are made freely, but safety testing is often missing.
His advice is clear and direct. Stay away from advertised “exotic herbal drinks.” They are neither proven safe nor proven beneficial, and the risk to your liver may be far greater than you realize.
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A simple drink costing just 22p per serving could benefit your heart. Recent research suggests that orange juice may help reduce blood pressure and inflammation, which are two major risk factors for cardiovascular disease.
Cardiovascular disease remains a leading health concern in the UK, responsible for roughly a quarter of all deaths each year. This umbrella term covers conditions affecting the heart and blood vessels, including coronary artery disease, stroke, heart failure, and irregular heart rhythms.
While medications exist to manage these conditions, health authorities recommend lifestyle adjustments as well. Among these, dietary changes are crucial, particularly reducing foods high in saturated fats.
Orange Juice Shows Promise for Heart Health
New research from the University of São Paulo in Brazil, published in Molecular Nutrition and Food Research, has revealed that orange juice can influence genes linked to high blood pressure and inflammation. These are key contributors to heart attacks, strokes, and heart failure.
Inflammation can damage blood vessels, constrict arteries, and promote plaque buildup. Orange juice was also shown to enhance genes involved in fat metabolism, supporting better processing and storage of fats in the body.
Layanne Nascimento Fraga, the study’s lead author, told Medical News Today: “We used a transcriptomic approach to observe the effects of orange juice on the entire metabolic system, allowing us to see multiple pathways working together. We found improvements in key cardiometabolic markers, including blood pressure, inflammation, oxidative stress, and lipid metabolism.”
The study identified 1,705 genes affected by orange juice, with 98% being downregulated, highlighting its broad impact on cardiovascular health.
The researchers noted that orange juice’s effects can vary based on an individual’s body weight. This provides insights for tailored dietary recommendations, particularly regarding flavonoid-rich foods like citrus. At the time of reporting, a litre of orange juice from Tesco cost 89p, making a 250ml serving roughly 22p.
This is not the first time orange juice has been linked to heart health. A 2023 study in Lipids in Health and Disease found that consuming two glasses (480ml) daily for at least a year led to significantly lower cholesterol levels in participants aged 18–66.
A meta-analysis reviewing nine studies also suggested that orange juice may improve levels of “bad” LDL cholesterol, though effects on total cholesterol and “good” HDL cholesterol were not significant.
A 2021 study in the European Journal of Nutrition further showed that hesperidin-enriched orange juice could reduce systolic blood pressure and pulse pressure, offering a potential tool for managing pre- and stage-1 hypertension.
It is important to remember that orange juice contains roughly 24 grams of sugar per serving, which should be considered when incorporating it into a daily diet, especially for those monitoring sugar intake.
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