Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that affects millions of people, both children and adults. The key characteristics are hyperactivity, impulsivity, and inattention. Because of many obstacles, researchers have been searching for other therapies—inclining to include diet intervention to control the symptoms of ADHD more effectively. One interesting area of research is that for chili peppers! Yes, you read it correctly, scientists are studying the effects of chilli peppers in order to help ease symptoms of ADHD through their action on gut microbiota and the gut-brain axis.

The gut-brain axis (GBA) is a two-way communication system that connects the gastrointestinal tract with the central nervous system. It has significant roles in brain function, emotional control, and cognitive processes. The most recent research indicates that gut microbiota- bacteria living in the digestive system can potentially affect ADHD by impacting the production of neurotransmitters and brain structure.

People with ADHD tend to have reduced levels of healthy gut bacteria, including Lactobacillus, and a less diverse gut microbiota. This imbalance can contribute to greater neuroinflammation and oxidative stress, both of which are involved in ADHD pathology.

Gut microbiota also control the production of dopamine and serotonin, two neurotransmitters critical for attention, impulse control, and emotional stability.

Can Chili Peppers Be A Natural Treatment For ADHD?

Chili peppers have bioactive molecules, such as capsaicin, vitamin C, and polyunsaturated fatty acids (PUFAs), that could affect symptoms of ADHD through modulation of the gut microbiota and neurotransmitter concentration.

Capsaicin, the phytochemical in chili peppers, has been found to modulate neurotransmitter levels. Experiments with animals reveal that capsaicin boosts the levels of serotonin and dopamine in the brain, which has the potential to enhance attention and impulse control.

Additionally, capsaicin has been shown to inhibit neuroinflammation and oxidative stress, both of which are associated with ADHD pathology. Through the reduction of these variables, capsaicin could help to decrease some ADHD symptoms. While animal models offer promising information, human studies are needed to ascertain if capsaicin supplementation can produce a concrete effect on ADHD symptoms.

Role of Vitamin C and Gut Microbiobe

Chili peppers are a rich source of vitamin C, a potent antioxidant that enhances immune function, neurotransmitter production, and iron absorption. New evidence indicates that vitamin C can also increase the prevalence of helpful microbes such as Lachnospiraceae in the gut microbiota. Gut microbial balance has been implicated in neurodevelopmental diseases such as ADHD, and vitamin C's activity in regulating gut microbes could potentially be used as a therapy.

Moreover, vitamin C also decreases brain inflammation, which tends to be higher in patients with ADHD.

Chili peppers are also rich in PUFAs, such as omega-3 and omega-6 fatty acids. Studies have established that patients with ADHD tend to have lower levels of omega-3 PUFAs, which are important for brain function, synaptic plasticity, and regulation of neurotransmitters. Omega-3 supplementation has been shown to enhance memory function and boost short-chain fatty acid (SCFA)-producing gut bacteria, which promote brain and gut health.

Given that PUFAs have anti-inflammatory properties and maintain cognitive function, their occurrence in chili peppers contributes to the accumulating data indicating dietary intervention may be effective in modulating ADHD symptoms.

Although chili peppers have bioactive substances that could affect the gut-brain axis and help alleviate ADHD symptoms, their impact is speculative until stricter human trials are carried out. Being a readily available food item, peppers can be used as a possible adjunct therapy, which can be added to conventional ADHD treatments. Peppers, however, cannot be used as a substitute for established medical therapies, including behavioral therapy and prescription drugs.

The developing connection between nutrition, gut microbiome, and ADHD has paved the way for exploring non-medication interventions. Chili peppers, rich in capsaicin, vitamin C, and PUFAs, represent a novel yet unproven method for modulating ADHD symptoms. While early research points towards a possible intervention by chili peppers in modulating neurotransmitter content and minimizing neuroinflammation, human studies are essential to validate the observations.

Your gut's petrol maybe running low and it is causing you all sorts of gut issues. But, what does it really mean?

Bloating that doesn’t settle, gas that feels unpredictable, sluggish digestion, and a constant sense that your gut just isn’t cooperating anymore. All of these complaints are becoming increasingly common, especially in urban India. While many people blame stress or food intolerances, experts say the issue may lie deeper, at the level of the gut microbiome. One key reason: falling levels of butyrate, a small but powerful compound essential for gut health.

Often described as the gut’s “petrol,” butyrate plays a critical role in keeping the digestive system resilient and balanced.

What Is Butyrate and Why Does It Matter?

Butyrate is a short-chain fatty acid (SCFA) produced when beneficial gut bacteria ferment dietary fiber. Think of it as the primary fuel source for the cells lining the colon. When enough butyrate is present, the gut lining stays strong, inflammation remains under control, and digestion functions smoothly.

When levels drop, the gut barrier weakens. This can lead to inflammation, slower digestion, immune imbalance, and even disruptions in metabolism and mood. In simple terms, low butyrate means the gut struggles to repair and protect itself.

A Silent Deficiency on the Rise

Recent gut microbiome analyses suggest that butyrate levels are declining sharply, particularly among adults living in metro cities. The drop isn’t limited to older age groups, even people in their 20s and 30s are showing early signs of imbalance.

While other SCFAs like propionate and acetate may remain relatively stable, butyrate appears to be the first to fall. This imbalance is increasingly being linked to rising cases of irritable bowel symptoms, unexplained digestive discomfort, and metabolic issues, even when routine tests appear normal.

What Low Butyrate Says About Your Gut

Low butyrate usually signals one of two problems, or both. Either the butyrate-producing bacteria are disappearing, or the diet lacks the fibers those bacteria depend on. Many people believe they eat “healthy,” yet still miss out on fiber diversity.

Without adequate fuel, beneficial bacteria struggle to survive. As a result, the gut ecosystem shifts, leading to symptoms such as bloating, cramps, urgency, alternating constipation and loose stools, fatigue, brain fog, and sugar cravings. These issues often go undetected because structural tests show no obvious damage.

How Modern Diets Are Fueling the Problem

Traditional Indian diets once provided a wide range of fibers through millets, dals, vegetables, fermented foods, and seasonal produce. Over time, these have been replaced by ultra-processed foods that are low in fiber and high in sugar and refined carbohydrates.

Add irregular meal timings, chronic stress, poor sleep, frequent antibiotic or painkiller use, and environmental pollution, and the gut microbiome takes a hit. The bacteria that produce butyrate simply fade away, much like shutting down a factory that no longer receives raw materials.

Rebuilding Butyrate Naturally

Restoring butyrate isn’t about quick fixes. Supplements may provide temporary relief, but they don’t rebuild the ecosystem. The foundation is dietary diversity.

Foods that help feed butyrate-producing bacteria include millets, legumes, whole grains, fruits, vegetables, seeds, and resistant starches. Everyday foods such as bananas, onions, garlic, oats, and cooked-and-cooled rice act as natural prebiotics. Fermented foods like curd and buttermilk also support microbial balance.

With consistent changes, the gut can slowly restart its butyrate production, though meaningful recovery may take several months.

Why Fiber Awareness Matters More Than Ever

Low butyrate isn’t just a digestive issue. It reflects how modern lifestyles are reshaping gut health at a population level. Improving fiber diversity could strengthen immunity, metabolism, and long-term health more effectively than treating symptoms later.

In many ways, restoring butyrate means returning to simpler, whole-food eating habits — and giving the gut the fuel it was designed to run on.

Millions of people are stocking up on food for Christmas, planning the main meal and everything that comes with the festive stretch. What many do not realise is that there is a proven link between cancer and one much-loved item that often sits on the Christmas Day plate.

While sugar is often blamed for causing cancer, that belief is not supported by evidence. In fact, only two foods have a confirmed, direct link to cancer: alcohol and processed meat. And popular pigs in blankets clearly fall into the processed meat category.

Popular Christmas Food Could Raise Your Risk of Cancer And Heart Attack

To be clear, no one is saying that eating pigs in blankets on Christmas Day will give you cancer, just as no one suggests that a single glass of wine or sherry will lead to a diagnosis. That said, recent scientific evidence shows there is no truly safe level of alcohol consumption. In a recent report, Vivek Murthy, former surgeon general of the US Public Health Service, warned that alcohol use has been directly linked to at least seven different types of cancer, and that even light or moderate drinking can raise a person’s cancer risk.

As per Mirror, both processed meat and alcohol are classified as Group 1 carcinogens by the World Health Organisation, which means there is clear evidence they can cause cancer in humans. According to the WHO, “There is convincing evidence that the agent causes cancer.” Tobacco smoking and asbestos are also listed as Group 1 carcinogens, although the organisation clarifies that this does not mean alcohol and processed meat are as dangerous as smoking or asbestos.

Cancer Research UK also states clearly, “We know for certain that processed meat causes cancer. We are as confident about this link as we are about other established causes of cancer, such as tobacco and alcohol.”

What Is Processed Meat?

Cancer Research UK explains that processed meats contain chemicals that are either added during processing or formed during cooking. These include nitrates and nitrites, which help keep processed meat fresh for longer. The organisation notes, “When we consume them, nitrates and nitrites can turn into N-nitroso chemicals (NOCs), which can damage the cells lining the bowel. This damage can increase the risk of bowel cancer.”

Why Does Alcohol Cause Cancer?

Alcohol increases cancer risk through biological processes that occur as it is broken down in the body. This means that any alcoholic drink, regardless of how expensive, high-quality, or mild it may seem, carries a cancer risk. There is no safe threshold for drinking alcohol. The WHO says cancer risk “rises significantly the more alcohol is consumed,” but also points out that “the latest available data show that around half of all alcohol-related cancers are caused by ‘light’ and ‘moderate’ drinking,” defined as less than 1.5 litres of wine, less than 3.5 litres of beer, or under 450 millilitres of spirits per week.

Processed Meat And Heart Disease

In 2021, researchers at Oxford University reported that the “largest review of all large-scale studies to date shows red and processed meat increase the risk of heart disease.”

Worldwide, coronary heart disease causes nearly nine million deaths each year, making it the leading cause of death globally. Scientists from the University of Oxford’s Nuffield Department of Population Health said their analysis “showed that each additional 50g per day of processed meat, such as bacon, ham, or sausages, was linked to an 18% higher risk of coronary heart disease.”

Eating is something we do every day, and its connection to our weight is undeniable. Most of us concentrate on what we eat, and rightly so, because the nutritional value and calorie content of food directly impact our weight. Yet, an increasingly important factor in weight management is when we eat. Nutritionist Pooja Makhija explains the science behind having early dinners, particularly in the evening, and how this aligns with the body clock to support overall weight management.

In an Instagram video, she writes in the caption, “You don't start digesting worse at night because of the food… you digest worse because melatonin has already risen,” adding, “Melatonin climbs 2–3 hours before your bedtime, dropping your insulin sensitivity by up to 50% and switching fat cells into storage mode. So the same meal hits very differently at 7 pm vs 10 pm.”

What Is Melatonin?

Melatonin is a hormone made by the pineal gland in the brain that helps control the body’s sleep-wake cycle. Its levels usually rise in the evening, peak during the night, and fall in the early morning. Many doctors even recommend melatonin supplements to help regulate sleep patterns, though they can sometimes cause side effects, so consulting a physician is advised, as per Healthline.

How Does Melatonin Affect Your Fat Storage In Body?

In her video, Pooja grabs attention by asking, “We all know that melatonin makes you sleepy. But what if I told you that melatonin wakes up your fat cells and makes them store more? Hadn't heard of that?”

She continues, “Melatonin isn’t just your sleep hormone. It’s your body’s night mode switch. As it rises in the evening, your metabolism slows down. Insulin sensitivity drops 25 to 50 percent, glucose clearance slows, and your fat cells switch from burning energy to storing it.” Referring to a study published in the *Clinical Endocrinology and Metabolism* journal, she adds, “People who ate dinner when their melatonin was high had a 34 percent higher glucose spike. Same people, same meal, same calories—just bad timing.”

What Is Front Loading Calories?

Front-loading calories is a way of eating where most of your daily calories are consumed earlier in the day, with a big breakfast and hearty lunch and a lighter dinner in the evening. This approach matches your meals with your body’s natural circadian rhythms, improving metabolism, insulin response, and appetite control. It helps with weight management and energy levels by taking advantage of the morning metabolism, reducing late-night cravings, and supporting better sleep.

What Is The Correct Time To Have Dinner To Prevent Fat Storage And Weight Gain?

Pooja Makhija says the most effective method to prevent melatonin from triggering fat storage is to eat early dinners and front-load calories during the day.

“So when most of your calories land late at night, it’s at a time when your biology is saying, ‘I’m done for the day; I’m not burning more.’ In contrast, front-loading calories with a big breakfast, solid lunch, and small dinner means you’re eating when melatonin is low. Your insulin is sharp, mitochondria are active, and your body is in daytime burning mode,” she explains.

She concludes with a reminder: “Your fat cells have melatonin receptors, and they behave differently depending on the time of day. Front-loading isn’t a hack—it’s circadian biology. Melatonin guides your metabolism. So eat in tune with your body clock, not against it, and notice the difference.”

According to Healthline, the ideal dinner time for better melatonin regulation and metabolism is 2–3 hours before bedtime—before your body naturally begins releasing melatonin—to avoid insulin spikes and fat storage.