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For many people, black coffee is the go-to morning pick-me-up. But could this beloved beverage do more than just wake you up? Emerging research suggests that black coffee might help reduce fat accumulation around the liver, a key factor in conditions like non-alcoholic fatty liver disease (NAFLD).
The liver plays a crucial role in filtering toxins, processing nutrients, and regulating metabolism. However, excessive fat deposits around the liver can impair its function, increasing the risk of inflammation, insulin resistance, and even liver disease.
Recent studies indicate that coffee, particularly black coffee, may offer protective benefits. The magic lies in its rich composition of bioactive compounds, including caffeine, chlorogenic acid, and polyphenols. These compounds are known for their antioxidant and anti-inflammatory properties, which may help combat fat buildup in the liver.
Several studies have examined the effects of coffee on liver fat. A 2021 study published in the Journal of Clinical Medicine found that individuals who consumed more than three cups of coffee daily had lower liver fat levels compared to non-coffee drinkers. Researchers believe this is due to coffee’s ability to enhance fat metabolism and reduce oxidative stress in liver cells.
Another study, conducted by researchers from the University of Naples, suggested that caffeine stimulates the breakdown of lipids (fat molecules), potentially preventing fat accumulation in the liver. Additionally, chlorogenic acid—one of coffee’s key antioxidants—has been found to reduce insulin resistance, a major contributor to fatty liver disease.
Unlike sugar-laden coffee drinks, plain black coffee is free of added calories and unhealthy fats. Here’s how it might contribute to a healthier liver:
Boosts Metabolism: Caffeine is a natural stimulant that increases metabolic rate, promoting fat burning.
Reduces Inflammation: Coffee’s antioxidants help lower liver inflammation, which is a major factor in the progression of liver diseases.
Improves Insulin Sensitivity: Better insulin regulation means less fat storage in the liver.
Prevents Liver Fibrosis: Some studies suggest that coffee consumption reduces liver stiffness, lowering the risk of fibrosis and cirrhosis.
Moderation is key. Experts suggest that drinking 2–4 cups of black coffee per day may offer liver-protective benefits without causing negative effects like jitteriness, acid reflux, or disrupted sleep. However, those with caffeine sensitivity or certain health conditions should consult a doctor before increasing their intake.
While black coffee alone won’t magically melt away liver fat, it can be a valuable addition to a healthy lifestyle. Pairing it with a balanced diet, regular exercise, and avoiding excessive alcohol and processed foods is essential for long-term liver health.
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Eating about two servings of unsalted, skin-roasted peanuts daily may help support brain health, and reduce the risk of Alzheimer's Disease, suggests a study.
The study, conducted in older adults, suggests that eating 60 grams of peanuts daily for 16 weeks improved insulin responsiveness in brain regions involved in memory, a function that can weaken with age and is linked to Alzheimer's Disease.
Published in the peer-reviewed journal Food & Function, the study highlights how daily peanut consumption may influence brain insulin signalling. However, it does not establish that peanuts can prevent Alzheimer's disease.
The study included 31 healthy adults aged 60 to 75. During the peanut consumption phase, participants ate 60 grams (approximately two servings) of peanuts daily for 16 weeks.
Researchers used a randomized, controlled crossover trial, allowing them to compare the effects of eating peanuts with those of avoiding them.
The elderly who consumed peanuts daily showed improved insulin responsiveness in several brain regions in the right hemisphere. These included parts of the lingual gyrus, hippocampus, parahippocampal gyrus and posterior cingulate gyrus, all involved in memory-related processes.
While insulin is best known for regulating blood sugar, it also plays an important role in the brain. It supports nerve cell growth, survival and communication, helping maintain memory and other cognitive abilities.
Also read: Just Four Days Of High-Fat Diet May Increase Inflammation, Study Finds
Reduced brain responsiveness to insulin with age has been linked to cognitive decline.
"The hormone insulin plays an important role in the brain, where it supports memory and other cognitive processes. As people age, the brain may become less responsive to insulin, which has been linked to age-related cognitive decline," said Dr Peter Joris, associate professor in the Department of Nutrition and Movement Sciences at Maastricht University Medical Center, Netherlands.
"Our study found that daily peanut consumption beneficially affected insulin responsiveness in memory-related brain regions in older adults. These findings suggest that enhanced regional brain insulin responsiveness may contribute to the cognitive benefits of unsalted, skin-roasted peanut intake," he added.
Read More: Peanut Consumption Associated With Lower Type 2 Diabetes Risk: Study Explains
Researchers supplied participants with premeasured packets of skin-roasted peanuts to ensure consistent consumption.
Participants were instructed to eat their peanuts in the morning or afternoon. They could consume the entire portion at once, divide it into smaller servings throughout the day or include the peanuts in their meals.
Researchers believe several peanut components, rather than a single nutrient, may contribute to the observed effects.
"Multiple nutrients present in peanuts, including unsaturated fats, dietary fibre, vitamins and minerals and bioactive phytochemicals, could potentially contribute to the observed brain benefits," said Joris.
"Peanuts are also a good source of plant-based protein and are especially rich in L-arginine. L-arginine is a key precursor of nitric oxide (NO), which has been reported to facilitate learning and memory performance," he added.
Peanut and Improvements in Blood Flow and Verbal Memory
A previous study published in the peer-reviewed journal Clinical Nutrition 2025, found that consuming peanuts for 16 weeks increased overall cerebral blood flow (CBF) by 3.6% and improved verbal memory performance by 5.8%.
Cerebral blood flow measures the amount of blood circulating through the brain, delivering oxygen and nutrients that brain cells need to function. It is also an indicator of brain blood vessel health.
A burger, French fries and a soft drink represent high-fat fast food, which researchers say may influence immune responses and inflammation. (Image Credits: iStock)
Long-term diet and obesity are known to affect inflammation. A new study from the University of California, San Francisco suggests that even a few days of eating differently can change how strongly the immune system reacts, at least in mice.
The study was published in Nature on October 28. It was led by Sagar Bapat, a professor of pathology at UCSF and the paper’s corresponding author. Zewen “Owen” Jiang, who did the work as a graduate student at UCSF, was co-first author, according to UCSF.
The team raised mice on either low-fat or high-fat food pellets. They then applied imiquimod, a cream that triggers skin inflammation, to one ear of each mouse. Mice raised on high-fat food and made obese had severe reactions, while mice on low-fat food had mild ones.
Obesity has long been tied to more severe inflammation, but it wasn’t clear why. “We wanted to know whether it was the extra weight or simply the bad diet that was driving the stronger response,” Jiang said.
To find out, the researchers switched normal-weight mice from low-fat to high-fat food for just four days, then applied the cream three days later. These lean mice developed severe ear inflammation, just like the obese mice. In the other direction, obese mice moved to normal food for four days had much milder inflammation.
The paper’s conclusion is that the dietary state around the time inflammation starts, rather than obesity itself, determines how severe the disease gets.
Weeks later, the normal-weight mice were back on low-fat food and their inflammation had cleared. The researchers applied the cream again to the same ear. The reaction was far stronger than expected.
The researchers found that high-fat food drew rapid-response immune cells into the skin, which amplified the reaction. As the inflammation faded, memory T cells stayed behind in the ear. Together, these changes left the tissue primed for the next flare-up, UCSF reported. The paper also found that the response depends on CD4+ T cells, and that a protein complex called NLRP3 drives the diet-amplified disease.
The team saw a similar heightened response in the lungs after a few days on a high-fat diet.
Also Read: Psoriasis: Understanding The Skin Condition And Ways To Manage Flare-ups
“Long-term dietary habits absolutely matter for health, but our study unearthed a much more real-time influence of diet,” Bapat said. “Breakfast, lunch, dinner, they all can have a tremendous and rapid impact on the immune system.”
Jiang added a note of caution. “The diet of a laboratory mouse doesn’t map neatly onto what we eat, but it’s striking how quickly the immune system responds to what’s happening in the body right now,” he said. “Diet, exercise, sleep, they could all shape immune health in ways we don’t yet appreciate.”
This was a study in mice, and the high-fat pellets used in the lab are not the same as human meals. The findings don’t show that a single unhealthy meal will worsen a person’s skin or lung conditions. They do suggest that what is eaten around the time inflammation begins may matter more than researchers had assumed, and that the immune system may hold a memory of it.
Credit: Brigham Young University
An international team of 23 nutrition scientists has developed a food pyramid emphasizing plant foods, healthier fats and high-quality carbohydrates, offering an alternative to the Trump administration’s meat-heavy dietary advice.
Published in Advances in Nutrition, the International Food Guide Pyramid synthesizes evidence from more than 250 scientific publications and dietary guidelines from seven countries and regions.
“Despite what people often hear, there’s actually substantial agreement in nutrition science about the foundations of healthy eating,” said Karen Della Corte, a Brigham Young University nutritional scientist who led the team.
The pyramid focuses on three principles:
It encourages plant-based proteins such as beans, lentils, nuts and soy, without excluding fish, poultry, eggs or dairy. The guide can also be adapted for vegetarian and vegan diets.
The EAT-Lancet Commission estimates that adopting its proposed plant-forward diet could prevent approximately 15 million premature deaths annually.
The guide prioritizes whole grains and other high-quality carbohydrates over refined grains and sugary drinks. Carbohydrate quality depends on fiber content, processing, food structure and glycemic index (GI), which measures how carbohydrate-containing foods affect blood glucose.
“For both health and sustainability reasons, carbohydrate-rich foods should provide a substantial share of our energy, so their quality is particularly important,” said Anette Buyken, a professor at Paderborn University in Germany.
Traditional staples such as basmati rice, durum pasta, tortillas, rice noodles and bulgur can fit into a healthy diet, Della Corte said, depending on their glycemic index and preparation.
The pyramid also recommends choosing beans, peas, lentils, fish, poultry or yogurt more often than red and processed meats. It also advises replacing saturated fats, such as butter and animal fats, with unsaturated fats from sources such as olive and canola oils.
Other suggestions include choosing nuts, seeds, fruit or vegetables with hummus instead of processed snacks, whole-grain bread over refined white bread, and water instead of sugary soda.
The international pyramid contrasts with the Trump administration’s updated US dietary guidance, shaped by Health Secretary Robert F. Kennedy Jr.’s “Make America Healthy Again” (MAHA) agenda, which has emphasized meat and other animal-based foods.
Rather than prioritizing red meat, the international guide stresses plant proteins, unsaturated oils and higher-quality carbohydrates. It also considers the environmental impact of food production, including greenhouse gas emissions associated with livestock farming.
“Our diet has to be not only for our own health but also for the health of our planet,” said David Jenkins, a University of Toronto professor and creator of the glycemic index.
The guide also highlights the importance of limiting added sugars, particularly from sugary drinks, and favors water or sugar-free alternatives.
Working with the International Carbohydrate Quality Consortium, Della Corte compared dietary guidelines from Canada, Germany, Australia, China, the Netherlands, the United States and the Nordic countries. She also reviewed more than 250 scientific publications and drew on the EAT-Lancet Planetary Health Diet to identify shared principles of healthy eating.
The researchers say healthy eating does not require everyone to follow the same menu. Recommendations can be adapted to local food traditions, availability and budgets.
“When you’re designing a meal, start by thinking about the plant foods you want to emphasize,” Della Corte said. “What vegetables, whole or lower-GI grains, beans or lentils could you include?”
However, affordability and access can make healthier choices difficult.
“We need food environments that make it easy to put the pyramid’s recommendations into practice,” Buyken said, calling for nutrition policies that address food marketing, access and prices.
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