We all must have come across the phase: this is why women live longer than men. These are all over the social media, where men are performing more often than not, some experiments, without gears, just for fun, "in the name of science". The caption reads: this is why women live longer. However, is there really a science to it, other than the fact that women choose to do things more safely?

In the United States, women have a life expectancy of about 80, whereas men have 75. Women outlive men and this holds true regardless of the country women live, the money they make, and other factors. In fact, it is true for most other mammals too.

Dr Dena Dubal, a professor of neurology at the University of California, San Francisco told the New York Times, "It is a very robust phenomenon all over the world, totally conserved in sickness, during famines, during epidemics, even during the times of starvation."

But what are the reasons? These reasons are often more complicated and less established. It is important to note that only because women are outliving men does not mean they are living a better life. In fact, women tend to have shorter health spans, which means the number of healthy years in a person's life is less in women than men, confirmed Bérénice Benayoun, an associate professor at the U.S.C. Leonard Davis School of Gerontology.

As per a 2021 study titled, Sex differences in frailty: Comparisons between humans and preclinical models, found that women are more physically grail than men in old age. They are also more vulnerable, especially after menopause and are at more risk of developing cardiovascular issues and Alzheimer's disease because of age.

The key is in figuring out what makes one sex more resilient or vulnerable.

Genetics

For things which do not find easy explanations, scientists look for their answers in genes. Many research, including a 2020 study titled, The sex with the reduced sex chromosome dies earlier: a comparison across the tree of life, suggests that the XX set of female sex chromosomes may impact longevity. However, there has not been any clarity on how it affects longevity.

Another 2018 study titled, Female XX sex chromosomes increase survival and extend lifespan in aging mice, which was conducted by Dr Dubal's lab, looked at genetically manipulated mice with different combinations of sex chromosomes and reproductive organs. It was found that those with two X chromosomes and ovaries lived longest, followed by mice with two X chromosomes and testes. Mice with XY chromosomes had shorter life spans.

"There was something about the second X chromosome that was protecting the mice from dying earlier in life, even if they had testes. What if there was something on that second X chromosome that was in some ways a sprinkle of the fountain of youth," says Dr Dubal. While scientists have not yet looked at this factor in humans, Dr Dubal suggests that humans have the same hormones and sex chromosomes, and similar reproductive system that could corroborate the similar findings in people.

Hormones

Plenty research has shown that estrogen is responsible for longevity also effect on the immune system. The data also shows that before menopause, the female immune system tends to do better. In fact Dr Benayoun said that males tend to do much worse in response to infection.

Another 2017 study titled, Ages at Menarche and Menopause and Reproductive Lifespan As Predictors of Exceptional Longevity in Women: The Women's Health Initiative, found that women who experienced menopause later in life over the age 50 lived longer than those who experienced it earlier.

Lifestyle and Behavior

There are also disparity in behavioral patterns between men and women. This includes smoking, drinking heavily, which can contribute significantly to mortality. Women also have more "health promoting behavior", believe experts. Women are also more likely to socialize than men and thus it protects them from detrimental effects of social isolation and loneliness. In fact, a 2023 analysis published in Jama Network, titled, Widening Gender Gap in Life Expectancy in the US, 2010-2021, found that women are less likely to die by drug overdose or suicide.

Brain health is often associated with old age, but according to neurologists, the foundation for healthy cognitive function is laid much earlier.

On World Brain Day, they warned that the 30s and 40s are a crucial period to protect the brain, as lifestyle habits and underlying health conditions can quietly affect memory, concentration, and overall cognitive health.

Brain Ages Alongside the Heart

Speaking to HealthandMe, Dr. Gurucharan Adoor, Neurologist, Apollo Hospitals Bannerghatta Road, Bengaluru, said brain health is closely linked to cardiovascular health. High blood pressure, high cholesterol, and elevated blood sugar can silently damage the brain years before noticeable symptoms appear.

His advice? Make preventive health checks a routine by monitoring blood pressure, blood glucose or HbA1c, cholesterol, weight, and waist circumference—especially for people with a family history of diabetes, stroke, or early heart disease.

Brain Fog A Warning Signal

Also read: Neurological Disorders Emerging As India's Next Major Public Health Challenge, Say Experts

Dr. Adoor said sleep is often the first thing people sacrifice during their busiest years, but the brain pays the price.

Irregular sleep schedules, untreated sleep apnea, and repeated nights of poor-quality sleep can lead to mental fatigue, difficulty concentrating, and persistent brain fog. If brain fog continues, he said, it should not be ignored, as it may indicate an underlying health issue that requires attention.

Dr. Bhushan Joshi, Consultant Neurologist, Manipal Hospital, Kharadi, Pune, told HealthandMe that he is "seeing more professionals in their 30s and 40s complaining of brain fog than ever before". According to him, hormonal changes and chronic inflammation are among the common but often overlooked causes.

Hormonal Changes Can Affect Cognitive Function

Dr. Joshi noted that hormonal fluctuations can significantly influence brain function. Women entering perimenopause may experience difficulty concentrating, while others may notice "word retrieval and short-term memory due to changing estrogen levels that influence brain function."

He added that it is not limited to women. Men also undergo age-related hormonal changes that can affect energy levels and cognitive performance. While these changes are often temporary, they can still be distressing.

Read More: Aspartame, Saccharin, Erythritol Linked To Faster Brain Ageing: Study

Chronic Inflammation May Reduce Mental Clarity

Dr. Joshi explained that chronic low-grade inflammation can also contribute to brain fog. Conditions such as obesity, diabetes, autoimmune diseases, and persistent infections can trigger inflammatory responses that interfere with the brain's ability to process information efficiently. In some people, inflammation has been linked to reduced attention, poor memory, and diminished mental clarity.

Small Lifestyle Changes Key

The good news: Simple daily habits can support long-term brain health. Regular physical activity—whether it's walking, cycling, dancing, or strength training several times a week—improves blood flow to the brain, boosts mood, and supports healthy ageing.

Dr. Adoor also recommends limiting unnecessary screen time, taking regular breaks from phones and digital devices, and focusing on one task at a time to reduce mental overload.

When Should You See A Doctor?

Occasionally feeling mentally sluggish is common, but worsening memory problems or cognitive changes that begin interfering with work or daily life should not be ignored, Dr. Joshi said.

He added that these symptoms may stem from treatable conditions such as thyroid disorders, vitamin deficiencies, anxiety, or depression, making timely medical evaluation important.

Insufficient sleep can impact the brain. A good night's sleep allows the brain to repair and even recharge. Poor sleep over time can increase the risk of several neurological disorders and affect overall brain health.

This article helps to understand how poor sleep can take a toll on neurological health. Read on to know more about this and get a sound sleep at night.

Currently, due to hectic schedules, people are now sacrificing sleep to meet work deadlines, study longer, or spend more time on screens. Missing a few hours of sleep once in 2-3 months is harmless.

However, chronic sleep deprivation can not only cause irritation and weight gain but also neurological issues. During sleep, the brain processes memories, repairs nerve cells, regulates emotions, and clears waste products that accumulate throughout the day.

When sleep is disturbed on a regular basis, there can be a risk of neurological problems over time.

How Poor Sleep Affects The Brain

Also read: The Silent Impact of Stress On Your Brain: How Chronic Stress Affects Memory, Focus, And Mental Health

If you are one of those who is unable to get a sound sleep at night, then beware. If you are a night owl, then you will have to ensure you sleep well now.

Sleep helps the brain store and organise new information. Lack of sleep can make it difficult to concentrate, learn new skills, and remember important details. Many will also experience poor decision-making.

Poor sleep, especially when associated with conditions like sleep apnoea, can increase blood pressure and reduce oxygen supply, raising the risk of stroke in the near future.

Long-term sleep deprivation may reduce the brain's ability to clear harmful proteins such as beta-amyloid, which are linked to Alzheimer's disease and other forms of dementia.

People who sleep too little or have poor-quality sleep can also suffer from constant headaches and migraine attacks. In people living with epilepsy, inadequate sleep is a common trigger for seizures. Poor sleep increases the risk of anxiety, depression, irritability, and emotional stress.

Tips For Better Brain Health Through Sleep

It is necessary to get at least 7-9 hours of sleep per day. Maintain a consistent sleep and wake-up schedule.

Avoid screens, caffeine, and heavy meals before hitting the sack. Exercise regularly but avoid intense workouts late at night.

Keep your bedroom quiet, cool, and dark so that you can sleep better. Seek help from the doctor if you snore loudly, stop breathing during sleep, or feel excessively sleepy during the day.

So, just like a balanced diet, exercise, and staying stress-free by doing yoga and meditation, getting a good night’s sleep is also important. Sleep well and prevent any neurological issues.

In today's fast-paced world, stress has become an unavoidable part of life. While short-term stress can help us stay alert and respond to challenges, prolonged or chronic stress can have a significant impact on brain health.

On the occasion of World Brain Day, it is important to raise awareness about how unmanaged stress can silently affect memory, concentration, emotional well-being, and overall quality of life.

How Chronic Stress Affects the Brain

When the body is under constant stress, it releases higher levels of cortisol, commonly known as the stress hormone. Persistently elevated cortisol can interfere with the normal functioning of the brain, particularly areas responsible for learning, memory, and decision-making.

Individuals may experience forgetfulness, difficulty concentrating, reduced productivity, irritability, anxiety, and disturbed sleep. If left unaddressed, chronic stress may also increase the risk of depression and other mental health disorders.

How to Protect Your Brain from Stress

The good news is that the brain has an incredible ability to recover when stress is managed effectively. Adopting healthy lifestyle habits such as regular physical activity, adequate sleep, mindfulness practices, balanced nutrition, and maintaining meaningful social connections can significantly reduce stress levels and protect brain function. It is equally important to recognize when stress becomes overwhelming and seek timely professional support.

Prioritize Brain Health

Brain health is just as important as heart health, and taking care of our mental well-being should never be overlooked. This World Brain Day, let us prioritize stress management as an essential part of a healthy lifestyle. By identifying the early signs of chronic stress and making positive lifestyle changes, we can preserve memory, improve focus, enhance emotional resilience, and ensure a healthier brain for years to come.