We all must have come across the phase: this is why women live longer than men. These are all over the social media, where men are performing more often than not, some experiments, without gears, just for fun, "in the name of science". The caption reads: this is why women live longer. However, is there really a science to it, other than the fact that women choose to do things more safely?

In the United States, women have a life expectancy of about 80, whereas men have 75. Women outlive men and this holds true regardless of the country women live, the money they make, and other factors. In fact, it is true for most other mammals too.

Dr Dena Dubal, a professor of neurology at the University of California, San Francisco told the New York Times, "It is a very robust phenomenon all over the world, totally conserved in sickness, during famines, during epidemics, even during the times of starvation."

But what are the reasons? These reasons are often more complicated and less established. It is important to note that only because women are outliving men does not mean they are living a better life. In fact, women tend to have shorter health spans, which means the number of healthy years in a person's life is less in women than men, confirmed Bérénice Benayoun, an associate professor at the U.S.C. Leonard Davis School of Gerontology.

As per a 2021 study titled, Sex differences in frailty: Comparisons between humans and preclinical models, found that women are more physically grail than men in old age. They are also more vulnerable, especially after menopause and are at more risk of developing cardiovascular issues and Alzheimer's disease because of age.

The key is in figuring out what makes one sex more resilient or vulnerable.

Genetics

For things which do not find easy explanations, scientists look for their answers in genes. Many research, including a 2020 study titled, The sex with the reduced sex chromosome dies earlier: a comparison across the tree of life, suggests that the XX set of female sex chromosomes may impact longevity. However, there has not been any clarity on how it affects longevity.

Another 2018 study titled, Female XX sex chromosomes increase survival and extend lifespan in aging mice, which was conducted by Dr Dubal's lab, looked at genetically manipulated mice with different combinations of sex chromosomes and reproductive organs. It was found that those with two X chromosomes and ovaries lived longest, followed by mice with two X chromosomes and testes. Mice with XY chromosomes had shorter life spans.

"There was something about the second X chromosome that was protecting the mice from dying earlier in life, even if they had testes. What if there was something on that second X chromosome that was in some ways a sprinkle of the fountain of youth," says Dr Dubal. While scientists have not yet looked at this factor in humans, Dr Dubal suggests that humans have the same hormones and sex chromosomes, and similar reproductive system that could corroborate the similar findings in people.

Hormones

Plenty research has shown that estrogen is responsible for longevity also effect on the immune system. The data also shows that before menopause, the female immune system tends to do better. In fact Dr Benayoun said that males tend to do much worse in response to infection.

Another 2017 study titled, Ages at Menarche and Menopause and Reproductive Lifespan As Predictors of Exceptional Longevity in Women: The Women's Health Initiative, found that women who experienced menopause later in life over the age 50 lived longer than those who experienced it earlier.

Lifestyle and Behavior

There are also disparity in behavioral patterns between men and women. This includes smoking, drinking heavily, which can contribute significantly to mortality. Women also have more "health promoting behavior", believe experts. Women are also more likely to socialize than men and thus it protects them from detrimental effects of social isolation and loneliness. In fact, a 2023 analysis published in Jama Network, titled, Widening Gender Gap in Life Expectancy in the US, 2010-2021, found that women are less likely to die by drug overdose or suicide.

More than 10 million adults, young people, and children in the UK are currently living with arthritis, according to a 2025 report by Arthritis UK. The NHS says osteoarthritis is the most common form of the condition across the country.

NHS Issues Warning For People Taking NSAIDs For Osteoarthritis

Osteoarthritis develops when joints become stiff and painful over time. Symptoms vary widely depending on the joint involved and the severity of damage. While medication is often used to manage pain and inflammation, the NHS warns that some commonly used treatments can carry risks if not taken correctly.

One of the most widely used options for pain relief is NSAIDs, a group of medicines many people rely on daily.

What Are NSAIDs And Why Are They Prescribed?

NSAIDs, or non-steroidal anti-inflammatory drugs, are commonly prescribed by GPs to relieve pain, swelling, and inflammation. They are available in several forms, including tablets, capsules, suppositories, creams, gels, and injections. Some NSAIDs can be bought over the counter, while stronger versions require a prescription.

Common types of NSAIDs

The most commonly used NSAIDs include:

• ibuprofen
• naproxen
• diclofenac
• celecoxib
• mefenamic acid
• etoricoxib
• indomethacin
• aspirin for pain relief (low-dose aspirin is not usually classed as an NSAID)

Doctors usually advise which NSAID is suitable and explain the potential benefits and risks. However, the NHS stresses that patients should also understand possible side effects and when to seek medical help.

NHS Warning On Who Should Be Cautious With NSAIDs

The NHS advises that NSAIDs may not be suitable for everyone. Extra caution is needed if you have asthma, stomach ulcers, angina, or if you have previously had a heart attack or stroke. People taking low-dose aspirin should always speak to their GP before using an NSAID.

Who Should Avoid Or Seek Advice Before Taking NSAIDs?

You should consult a pharmacist or doctor before using NSAIDs if you:

• are over the age of 65
• are pregnant or trying to conceive
• are breastfeeding
• have asthma
• have had an allergic reaction to NSAIDs in the past
• have a history of stomach ulcers
• have heart, liver, kidney, blood pressure, circulation, or bowel problems
• are taking other medicines
• are buying medicine for a child under 16 (aspirin should never be given to children under 16)

The NHS explains that NSAIDs are not always completely avoided in these cases, but they should only be used with medical advice, as the risk of side effects may be higher.

If NSAIDs are unsuitable, doctors or pharmacists may recommend alternatives such as paracetamol.

Possible Side Effects Of NSAIDs

Over-the-counter NSAIDs generally cause fewer side effects than prescription-strength versions. However, risks increase when they are taken at high doses, used for long periods, or taken by older adults or people with underlying health conditions.

Possible side effects include:

• indigestion, stomach pain, nausea, and diarrhoea
• stomach ulcers, which can lead to internal bleeding and anaemia
• headaches
• drowsiness
• dizziness
• allergic reactions

In rare cases, NSAIDs can affect the liver, kidneys, heart, or circulation, and may increase the risk of heart failure, heart attacks, or strokes.

Taking NSAIDs Alongside Other Medicines

It is essential to seek medical advice before taking NSAIDs if you are already using:

• another NSAID
• low-dose aspirin or warfarin
• ciclosporin
• diuretics for high blood pressure
• lithium
• methotrexate
• selective serotonin reuptake inhibitors (SSRIs) such as citalopram or fluoxetine

Signs And Symptoms Of Osteoarthritis

Common symptoms of osteoarthritis include joint pain, stiffness, and difficulty moving the affected joints. Some people may also experience:

• swelling
• joint tenderness
• a grating or crackling sensation when moving joints
• pain and stiffness after periods of inactivity
• enlarged or knobbly joints
• reduced range of movement
• muscle weakness or muscle loss

The NHS notes that osteoarthritis can affect almost any joint but most commonly involves the knees, hips, and small joints of the hands. Anyone with persistent symptoms should see their GP for diagnosis and treatment advice.

Even people who do not fall into higher-risk groups should only use NSAIDs as directed by a healthcare professional. Side effects can still occur, especially with long-term use. If NSAIDs are not appropriate, safer alternatives may be suggested to manage pain effectively.

Following the water contamination emergency in Indore, similar concerns have now surfaced in Madhya Pradesh’s capital. Groundwater samples collected from four locations in Bhopal have tested positive for E. coli bacteria. In response, the Bhopal Municipal Corporation has barred residents from using groundwater for any purpose.

Officials clarified that the contamination is restricted to underground water sources and has not spread to the treated piped water supplied across the city. According to ANI, civic teams have tested 1,810 water samples so far and inspections are still underway in all zones.

E. coli was the same bacteria responsible for Indore’s recent water crisis, which claimed 20 lives, including that of a five-month-old infant. As per a report by Dainik Bhaskar, fear has gripped several neighbourhoods in Bhopal, with residents hesitant even to touch the water. Locals say the water is unfit not only for drinking but also for washing hands, utensils, or bathing. In some areas, tap water reportedly turns reddish within minutes and emits a strong, foul smell. Adding to the concern, iron levels in the water are said to be nearly 100 times above permissible limits.

Here is what you need to know about E. coli, how it spreads, its symptoms, and ways to stay safe.

What Is E. Coli Bacteria?

Escherichia coli, commonly known as E. coli, refers to a group of bacteria that naturally live in the intestines of humans and animals. Most of these strains are harmless and even play a role in digestion. However, certain types can trigger illness when they enter parts of the body where they do not belong or release harmful toxins.

These disease-causing strains attach themselves to body cells and produce toxins, leading to infection and inflammation.

What Happens During An E. coli Infection?

An E. coli infection occurs when harmful strains of the bacteria enter the body. It most often affects the digestive system, causing symptoms such as watery diarrhoea, abdominal pain, and gastroenteritis. In some cases, the bacteria can also infect the urinary tract.

Certain strains produce Shiga toxin, which can lead to severe complications, including kidney damage, especially in children and older adults.

Why E. coli Infections Occur?

E. coli has many strains. While some support gut health, others can cause serious illness. Experts classify the harmful types based on how they attach to cells and the toxins they release. Several strains are known to cause diarrhoeal diseases, including:

• Shiga toxin-producing E. coli (STEC)
• Enterotoxigenic E. coli (ETEC)
• Enteropathogenic E. coli (EPEC)
• Enteroaggregative E. coli (EAEC)
• Enteroinvasive E. coli (EIEC)
• Diffusely adherent E. coli (DAEC)

Other important strains include uropathogenic E. coli, which is a common cause of urinary tract infections, and E. coli K1, which can lead to meningitis in newborns, according to the Cleveland Clinic.

Common Signs Of E. coli Infection

An infection affecting the gut often begins with digestive symptoms. These may include:

• Diarrhoea that is watery and sometimes blood-stained
• Abdominal pain and cramping
• Reduced appetite
• Mild fever

The Cleveland Clinic notes that watery diarrhoea is usually the earliest symptom when the gastrointestinal tract is involved. Symptoms can vary depending on which part of the body is infected.

How To Protect Yourself From E. Coli?

Preventing E. coli infection largely depends on basic hygiene and safe food practices. Since the bacteria spreads through contaminated food, water, and faecal matter, simple precautions can lower the risk significantly.

Maintain hand hygiene

Wash hands thoroughly with soap and water for at least 20 seconds before eating or cooking, after using the toilet, changing diapers, or handling animals. Proper handwashing removes bacteria and limits its spread.

Practice safe food handling

Use separate cutting boards and utensils for raw meat and ready-to-eat foods. Clean kitchen surfaces and tools with hot, soapy water after each use. Keep raw meat away from fruits and vegetables to avoid cross-contamination.

Cook food completely

Ground meat should be cooked to at least 160°F or 71°C, while poultry needs to reach 165°F or 74°C. Using a food thermometer ensures food is properly cooked and free from harmful bacteria.

Clean fruits and vegetables

Wash all produce under running water just before consumption, even if you plan to peel it. This helps remove bacteria picked up from soil or contaminated irrigation water.

Choose safe drinks

Consume only pasteurised milk and juices, and rely on boiled or treated municipal water. Avoid unpasteurised products and untreated water, as pasteurisation effectively eliminates dangerous E. coli strains.

We often hear of dementia as an adult, or older people's disease, but, a father from Glasgow shares how his four-year-old daughter was diagnosed with the condition. Childhood Dementia news of Darren Scott's daughter was delivered to him like a "complete thunderbolt", he tells Sky News. She was diagnosed with the condition before she turned four. Five doctors were waiting, when Sophia Scott, who had just turned four, were summoned to a Glasgow hospital room. Then came the worst news. Scott was told that his daughter could not live beyond the age of 16. "We were told... there was nothing they could do. It was a moment that broke us, shattered our lives. We have never recovered," he says.

What Is Childhood Dementia?

As per Dementia Australia, childhood dementia is a rare brain condition that affects one in every 2,900 babies globally. Childhood dementia is a group of serious brain conditions that interfere with a child’s memory, behavior, emotions and ability to communicate. It isn’t caused by lifestyle or ageing. Instead, it stems from more than 100 rare genetic disorders that children are born with. These include conditions such as Niemann-Pick type C, Batten disease and Sanfilippo syndrome.

No two children experience childhood dementia in the same way. The illness progresses differently for each child, but one thing remains constant: there is currently no cure. Like adult dementia, childhood dementia is progressive, meaning symptoms worsen over time. Heartbreakingly, around half of all affected children do not survive beyond the age of 10.

What causes childhood dementia?

Childhood dementia is genetic. Globally, about one in every 2,900 babies is born with a condition that can lead to childhood dementia. In Australia alone, an estimated 1,394 children were living with dementia in 2021.

The conditions that cause childhood dementia fall into several categories, including inborn errors of metabolism, lysosomal disorders, mitochondrial disorders, mucopolysaccharidoses, leukodystrophy, neurodegeneration with brain iron accumulation (NBIA), and peroxisomal diseases.

Signs and symptoms to look out for

Symptoms can begin in early childhood or appear much later, sometimes not showing up until the teenage years. The progression may be rapid or unfold slowly over several years, deeply affecting both the child and their family.

Much like adults with dementia, children may struggle with memory loss, confusion, changes in personality, anxiety or fear, and severe sleep disturbances. They may also find it difficult to concentrate, learn, communicate or understand things, and some experience behavioral challenges such as hyperactivity.

In addition, childhood dementia can affect the body beyond the brain. Children may develop problems with their bones or joints, experience issues with the heart, lungs or digestive system, lose their ability to move, see or hear, or have seizures.

As the condition advances, children gradually lose skills they once had — talking, walking, reading, writing and playing. Eventually, the body itself begins to shut down. Without major medical breakthroughs and more research, most children with childhood dementia will continue to face a shortened life, often not surviving beyond their teenage years.