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Do you know who can donate blood to you or who can you donate blood to? Blood donation may not be complex, but it does need to be compatible with yours and vice-versa. The blood types are determined by the presence or absence of certain antigens - substance that can trigger immune response if they are foreign to the body.
There are four major blood groups which are determined by the presence or absence of two antigens, A and B, on the surface of red blood cells. There is also a protein called the Rh factor, which can either be present (+) or absent (-), which creates A+, A-, B+, B-, O+. O-, AB+, AB- blood types.
Group A blood type has only A antigens on red blood cells and B antibody in the plasma. B has only B antigen on red cells and A antibody in the plasma. AB has both A and antigens on red cells, but neither A nor B antibody is present in the plasma. O has neither A nor B antigens on red cells, but both A and B antibody are present in the plasma.
Your blood type determines who can you donate to. This is because there are very specific ways in which blood types must be matched for safe transfusion. The right blood transfusion could actually save you, while the wrong one could be lethal. Also, Rh-negative blood is given to Rh-negative patients and Rh-positive or Rh-negative blood can only be given to Rh-positive patients.
If you are O blood type, you can donate to O, A, B, and AB, if you are A blood type, you can donate to A and AB, if you are B blood type, you can donate to B and AB, however if you are AB, you can only donate to AB.
If you are O blood type, you can only receive from O. If you are A, you can receive from type A and O. If you are blood type B, you can receive from type B and O. If you are AB, you are lucky, you can receive blood from O, A, B, and AB.
There are more than 600 other known antigens, the presence or absence of which creates "rare blood types". Certain types are unique to specific ethnic or racial groups, this is why an African-American blood donation can be the best hope for the needs of patients with sickle cell disease, as per the Red Cross Organization.
Type O is one in high demand, as it can donate blood to anyone. O negative blood type is the universal blood type, which can donate to everyone, especially during the emergency transfusions and for immune deficient infants.
In the US, 37% Caucasian, 47% African-American, 39% Asians, and 53% Latino-American are O-positive. However, only 8% of Caucasian, 4% of African-American, 1% Asian, and 4% Latino=Americans are O-negative.
A+: 33% Caucasian, 34% African-American, 27% Asian, 29% Latino-American
A-: 7% Caucasian, 2% African-American, .5% Asian, 2% Latino-American
B+: 9% Caucasian, 18% African-American, 25% Asian, 9% Latino-American
B-: 2% Caucasian, 2% African-American, .4% Asian, 1% Latino-American
AB+:3% Caucasian, 4% African-American, 7% Asian, 2% Latino-American
AB-: 1% Caucasian, .3% African-American, .1% Asian, .2% Latino-American
Credit: AI generated image
Psilocybin is the active ingredient found in magic mushrooms, and a new study shows that just one high dose (25 mg) is enough to cause alterations in the brain’s structures and help improve mental health.
The changes could explain why some people report psychological benefits from the experience, revealed the study published in the journal Nature Communications. The study found that the effect may last for up to a month after the experience.
In the study, researchers from the University of California, San Francisco, and Imperial College London argue that the effect may lead to “subsequent improvements in mental health”.
"Psychedelic means 'psyche-revealing,' or making the psyche visible," said senior author Robin Carhart-Harris, Professor of Neurology at UCSF.
"Our data shows that such experiences of psychological insight relate to an entropic quality of brain activity and how both are involved in causing subsequent improvements in mental health. It suggests that the trip—and its correlates in the brain—is a key component of how psychedelic therapy works," Carhart-Harris added.
Psilocybin has been the subject of several studies in people that have found it appears to alleviate symptoms of depression and anxiety. It has also shown promise in addiction medicine.
In the latest study on 28 people, none had a diagnosed mental health condition. The team gave the participants a 1 mg dose of psilocybin, which the researchers regarded as a placebo, and then monitored them with electroencephalography (EEG), which records brain activity from electrodes on the scalp.
One month after the placebo, the subjects were given 25 mg of psilocybin, a dose capable of eliciting a strong psychedelic trip.
After each experiment, the researchers measured the participants’ psychological insight, well-being, and cognitive ability. They also examined brain activity with functional MRI (fMRI) and brain connectivity with diffusion tensor imaging (DTI).
The results showed that within 60 minutes of taking the 25 mg dose of psilocybin, the EEG revealed higher entropy — which means that the brain was processing a richer body of information under the psychedelic.
A month later, the researchers looked at their subjects' brains with DTI, which measures the diffusion of water along neural tracts in the brain, and found that they were denser and had more integrity. This is the opposite of what happens in aging, which makes these tracts more diffuse.
Also Read: Ibogaine: Why Donald Trump Is Pushing US FDA To Fast-track This Psychedelic
While the result is a never-before-seen sign of how psychedelics can change the brain, the researchers cautioned that more work needs to be done to better understand the meaning of this change.
The participants noted that they had experienced more psychological insight after taking the 25 mg of psilocybin than they had after the 1 mg placebo, and noted "feeling optimistic about the future".
A month after the study, they also did better on a test of cognitive flexibility.
"Psilocybin seems to loosen up stereotyped patterns of brain activity and give people the ability to revise entrenched patterns of thought," said Taylor Lyons, a research associate at Imperial College London and the first author of the paper. "The fact that these changes track with insight and improved well-being is especially exciting."
The findings could improve treatment for people with mental illness with psilocybin, for example, by ensuring that the right dosage is used to produce the right amount of brain entropy to promote insight.
Uncontrolled eczema can also make sleep disorders worse. (Photo credit: AI generated)
Every year on May 5, World Asthma Day is observed, an event that aims at spreading awareness about the respiratory disorders. While asthma is becoming a common occurrence in India, citing excessive pollution and unhealthy lifestyle choices. But in a shocking revelation on the occasion, Dr. Gitika Sanodia, Consultant Dermatologist at Dr L H Hiranandani Hospital, Powai, revealed that leaving eczema untreated could lead to chronic asthma. Talking about it, Dr Sanodia answered some common FAQs about eczema and asthma.
Yes, especially for those suffering from early childhood onset of moderate/severe atopic dermatitis. Eczema is not always limited to being solely a skin condition. In many cases, patients who suffer from eczema actually have one part of the atopic triad, which means the patient's skin barrier is dysfunctional, allowing for allergens to enter and sensitize the immune system. With time, the same tendency can impact other organs, causing allergic rhinitis or asthma. However, it must be noted that not all children with eczema develop asthma.
Because of symptoms including itching, dryness, redness, scaling, and oozing from the skin. The families take care to control the acute phase of eczema while ignoring the patient's predisposition to allergies. Furthermore, atopic dermatitis is an inflammatory skin condition that is accompanied by impaired skin barrier function, immune dysfunction, and environmental factors. Moreover, according to DermNet, atopy is a term used for conditions where eczema, rhinitis, and asthma happen together.
Parents should worry if their children with eczema exhibit recurrent coughs, wheezing, noisy breathing, difficulties breathing during playtime, nighttime coughing, chest tightness, frequent sneezing, nasal blockage, allergic rhinitis, or exacerbation of symptoms following exposure to dust, animal dander, pollens, airborne particles, or fluctuating environmental conditions.
Successful treatment of eczema can help minimize the chances of allergens penetrating the skin barrier and allergic inflammation. Nonetheless, it would not be accurate to predict with certainty that eczema therapy will effectively prevent the onset of asthma. Literature recommends the prompt restoration of the skin barrier function, regular application of moisturizing agents, avoiding triggers such as fragrances and harsh soaps, managing flare-ups with prescription corticosteroid creams, controlling infections, and referring patients with severe eczema cases.
Yes. This condition is becoming more common, especially among children. If not controlled effectively, eczema will result in poor sleeping habits, difficulties with academic performance, reduced quality of life, greater susceptibility to infections, and potentially even links to other allergies. People lack sufficient information regarding the condition because they normally medicate themselves by applying whatever ointment or steroid to their skin.
Credit: AI generated image
Asthma is often thought of as an "outdoor" problem, with triggers such as smog, pollen, or car exhaust. But for many, the real danger may be sitting right there on the sofa or hiding under the sink.
The chronic condition affects over 260 million people. It is also responsible for over 450,000 deaths each year worldwide.
If you're doing everything right with your inhaler but still feel that tightness in your chest, it’s time to look at silent indoor triggers.
1. The Bedding "Dynasty"
“It’s a bit unsettling, but your mattress is likely home to millions of microscopic dust mites. They love the warmth and humidity of a bed. You won't see them, but you’ll feel them,” Dr. Sandeep Nayar, Principal Director & HOD - Chest & Respiratory Diseases, BLK Max Super Speciality Hospital, told HealthandMe.
The Fix: Don’t just wash your sheets; use hot water (60°C). If you haven't encased your pillows in allergen-proof covers yet, make that your priority this weekend.
2. Moisture is the Enemy
Dr Nayar said mold isn't always a giant green patch. It hides in the "sweat" behind your wallpaper or the damp corners of a bathroom that doesn't vent well. If a room smells even slightly musty, mold spores are likely in the air.
The Tip: Keep your home's humidity below 50 per cent. A simple dehumidifier can sometimes do more for your lungs than an extra dose of medicine.
3. It’s Not Just the Fur
Many people think "hypoallergenic" pets are the cure. It’s actually a protein in pet saliva and skin flakes (dander) that causes the flare-up.
The Reality: Even if you keep the dog off the bed, dander travels on your clothes. HEPA air purifiers are a must-have if you share your home with a furry friend.
4. The "Clean" Smell Myth
That "fresh lemon" scent or your favorite scented candle? Those are Volatile Organic Compounds (VOCs). To a sensitive lung, those chemicals are irritants, not cleaners.
The Switch: Move toward fragrance-free products. If a cleaning spray makes you cough, your body is telling you everything you need to know.
5. Urban Uninvited Guests
In cities, cockroach droppings are a massive, often ignored asthma trigger. Their proteins mix with household dust and get kicked up every time you walk across the floor.
The Strategy: Seal the cracks in your walls and keep the kitchen bone-dry.
Other asthma triggers include dust mites, pet dander, indoor smoke, and strong cleaning agents that can worsen symptoms over time
Dr. Manisha Mendiratta, Director & Head - Pulmonology, Sarvodaya Hospital, Faridabad, told HealthandMe that the key is prevention through simple, consistent habits. To make a meaningful difference, the expert urged people to
“Most importantly, patients should identify their personal triggers and act early, because managing their indoor environment is just as critical as managing their medication,” added Dr. Mendiratta.
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