Credits: Canva
Do you know who can donate blood to you or who can you donate blood to? Blood donation may not be complex, but it does need to be compatible with yours and vice-versa. The blood types are determined by the presence or absence of certain antigens - substance that can trigger immune response if they are foreign to the body.
There are four major blood groups which are determined by the presence or absence of two antigens, A and B, on the surface of red blood cells. There is also a protein called the Rh factor, which can either be present (+) or absent (-), which creates A+, A-, B+, B-, O+. O-, AB+, AB- blood types.
Group A blood type has only A antigens on red blood cells and B antibody in the plasma. B has only B antigen on red cells and A antibody in the plasma. AB has both A and antigens on red cells, but neither A nor B antibody is present in the plasma. O has neither A nor B antigens on red cells, but both A and B antibody are present in the plasma.
Your blood type determines who can you donate to. This is because there are very specific ways in which blood types must be matched for safe transfusion. The right blood transfusion could actually save you, while the wrong one could be lethal. Also, Rh-negative blood is given to Rh-negative patients and Rh-positive or Rh-negative blood can only be given to Rh-positive patients.
If you are O blood type, you can donate to O, A, B, and AB, if you are A blood type, you can donate to A and AB, if you are B blood type, you can donate to B and AB, however if you are AB, you can only donate to AB.
If you are O blood type, you can only receive from O. If you are A, you can receive from type A and O. If you are blood type B, you can receive from type B and O. If you are AB, you are lucky, you can receive blood from O, A, B, and AB.
There are more than 600 other known antigens, the presence or absence of which creates "rare blood types". Certain types are unique to specific ethnic or racial groups, this is why an African-American blood donation can be the best hope for the needs of patients with sickle cell disease, as per the Red Cross Organization.
Type O is one in high demand, as it can donate blood to anyone. O negative blood type is the universal blood type, which can donate to everyone, especially during the emergency transfusions and for immune deficient infants.
In the US, 37% Caucasian, 47% African-American, 39% Asians, and 53% Latino-American are O-positive. However, only 8% of Caucasian, 4% of African-American, 1% Asian, and 4% Latino=Americans are O-negative.
A+: 33% Caucasian, 34% African-American, 27% Asian, 29% Latino-American
A-: 7% Caucasian, 2% African-American, .5% Asian, 2% Latino-American
B+: 9% Caucasian, 18% African-American, 25% Asian, 9% Latino-American
B-: 2% Caucasian, 2% African-American, .4% Asian, 1% Latino-American
AB+:3% Caucasian, 4% African-American, 7% Asian, 2% Latino-American
AB-: 1% Caucasian, .3% African-American, .1% Asian, .2% Latino-American
Credit: Canva/WHO
Women can play a major role in preventing as well as eliminating Chagas Disease, a potentially life-threatening neglected tropical disease that affects 8 million people globally and causes 10,000 deaths every year, according to UN agencies.
World Chagas Disease Day is observed every year on April 14 to raise awareness around the disease, and the impact it has on lives.
In a statement, the Pan American Health Organization (PAHO) and the Global Chagas Coalition urged health authorities to make women central to the fight against the disease and to empower them to make early detection, prevention, and care.
“Eliminating Chagas disease as a public health problem requires placing women at the center of diagnosis, treatment, and care strategies,” said Dr. Jarbas Barbosa, PAHO Director.
“Ensuring timely access to quality health services, particularly for women of reproductive age, is essential to prevent new infections and advance toward the elimination of congenital Chagas disease in the Region of the Americas,” he added.
Chagas disease, also known as American trypanosomiasis, is a illness caused by the parasite Trypanosoma cruzi, and is primarily transmitted by triatomine insect vectors.
It gets spread through
If left untreated, one third of infected people—including women and the children they carry—will develop life-altering heart, digestive, and even neurological conditions, and may even become fatal.
Once endemic to 21 countries in Latin America, the disease has now spread globally due to migration. It is now a global health concern with cases found in 44 countries including the US, Canada, Europe, Australia, and Japan.
World Chagas Disease Day was celebrated for the first time in 2020.
The theme this year is “Women at the heart of care, protecting the next generation” and underscores the key role women play in family and community caregiving, as well as their greater interaction with health services, particularly during pregnancy.
Chagas Disease: Role Of Women
According to the World Health Organization (WHO), about 2 million women aged 15-44 years are living with Trypanosoma cruzi infection worldwide.
Congenital transmission or mother-to-child transmission remains a major challenge, occurring in about 3–5 percent of pregnancies. However, it also provides a key opportunity for effective intervention.
The transmission cycle of the disease can be effectively broken by
“On the contrary, it represents a strategic opportunity to strengthen more equitable, accessible, and responsive health systems that recognize and respect women’s needs.”
Credit: Naga Munchett/ Instagram
The BBC Breakfast host Naga Munchetty has opened up about her experience of suffering from a painful womb condition, known as the "evil twin sister of endometriosis".
The 51-year-old Naga Munchetty explained her condition as adenomyosis, which can cause extreme pain at any time. Munchetty added that she has faced the condition even while presenting her show, The Independent reported.
Naga Munchetty said that adenomyosis has caused her severe pain since she was in her teens, and she has “become conditioned to accept” it.
“If you’re curled up on the floor screaming, sweating, flooding, passing out, vomiting, that is debilitating. But you end up normalizing that pain.”
Adenomyosis is an extremely painful condition, which affects the womb and causes the uterus to enlarge. Although it affects an estimated one in 10 women, it remains undiagnosed in most women.
It is a lesser-known but significantly debilitating gynecological disorder that is commonly mistaken for endometriosis.
Adenomyosis leads to debilitating symptoms such as
Adenomyosis occurs when endometrial cells—typically restricted to the lining of the uterus—break through the myometrium, the muscular wall of the uterus.
Endometriosis, on the other hand, happens when tissue similar to the lining of the uterus grows outside the uterus. These tissues commonly develop on the ovaries, fallopian tubes, or the pelvic lining.
In contrast, adenomyosis is inside the uterus but produces serious complications. These out-of-place endometrial cells continue to act as they would in a regular menstrual cycle, becoming thick and shedding, which leads to internal bleeding, inflammation, and intense pain.
Despite going to the doctors several times, Naga Munchetty was not diagnosed until recently, as she was led to believe the pain she was experiencing was “normal”.
No absolute cure for adenomyosis exists except for a hysterectomy, which involves the removal of the uterus. Nevertheless, several treatment options can alleviate symptoms and enhance quality of life. These include:
1. Pain Relief
Ibuprofen and naproxen, over-the-counter pain medications, are usually prescribed to relieve menstrual cramps and pain.
2. Hormonal treatment such as
GnRH agonists, such as Lupron, induce temporary menopause by suppressing estrogen production, thereby reducing adenomyosis symptoms. However, these injections can cause severe side effects, including mood swings, hot flashes, and bone density loss, making them unsuitable for long-term use.
4. Surgical Intervention
According to experts, the brain is responsible for high BP. (Photo credit: iStock)
Hypertension, or high blood pressure, is caused by excessive salt intake; however, according to scientists, there are more reasons. Experts also blame a brain glitch. A part of the brain that makes us breathe while laughing or coughing could also cause a blood pressure spike, as per researchers from New Zealand and Brazil. This could explain why medication is not enough for controlling BP in some people. According to experts at the University of Auckland, there is a part of the brain that could cause high BP, thereby suggesting that the brain is responsible for hypertension.
Experts say that the lateral parafacial region is located in the brainstem. It is the oldest part of the brain and regulates heart rate, digestion, and breathing. Its action causes one to exhale during a cough, laugh, or workout. These actions are driven by abdominal muscles. Researchers also found that this area could connect to the nerves that tighten blood vessels and raise blood pressure. However, it is possible to reverse this action by inactivating this region.
Hypertension, or high blood pressure, is a condition wherein blood pushes against the walls of the blood vessels with too much force. Initially, it has no symptoms, but it is a silent killer. Over time, untreated high BP can lead to a stroke or a heart attack. While it is mostly believed to be a consequence of smoking, drinking alcohol, eating salty foods, and not exercising, experts have found other causes as well. As per research by the University of São Paulo in Brazil and the University of Auckland in New Zealand, published in the journal Circulation Research, rat brains had their brain cells in the lateral parafacial region switched off.
Researchers in the study successfully reactivated neurons in some rats and found that brain circuits ultimately raised BP. Experts mapped out what happened and compared it with rats that did not have hypertension. In the hypertensive group, lateral parafacial region neurons were helping with breathing but were also raising BP. This suggests that changes in breathing, which involve abdominal muscle contractions, can also trigger high BP. This is why patients with sleep apnoea experience interrupted breathing while sleeping and high blood pressure.
Apart from normal breathing, lateral parafacial region neurons are activated when oxygen levels are low. Experts also checked whether they could trigger the brainstem with medication. They noted that it was tricky because drugs would work on the entire brain and not a specific region. It could be activated by signals from the neck cells near the carotid artery. These can be safely targeted with medication.
To control persistent high BP, medication every day is a must. But to intensify the benefits, try the following simple tricks:
© 2024 Bennett, Coleman & Company Limited