Do you know who can donate blood to you or who can you donate blood to? Blood donation may not be complex, but it does need to be compatible with yours and vice-versa. The blood types are determined by the presence or absence of certain antigens - substance that can trigger immune response if they are foreign to the body.

There are four major blood groups which are determined by the presence or absence of two antigens, A and B, on the surface of red blood cells. There is also a protein called the Rh factor, which can either be present (+) or absent (-), which creates A+, A-, B+, B-, O+. O-, AB+, AB- blood types.

Group A blood type has only A antigens on red blood cells and B antibody in the plasma. B has only B antigen on red cells and A antibody in the plasma. AB has both A and antigens on red cells, but neither A nor B antibody is present in the plasma. O has neither A nor B antigens on red cells, but both A and B antibody are present in the plasma.

Blood Type And Who Can You Donate To?

Your blood type determines who can you donate to. This is because there are very specific ways in which blood types must be matched for safe transfusion. The right blood transfusion could actually save you, while the wrong one could be lethal. Also, Rh-negative blood is given to Rh-negative patients and Rh-positive or Rh-negative blood can only be given to Rh-positive patients.

If you are O blood type, you can donate to O, A, B, and AB, if you are A blood type, you can donate to A and AB, if you are B blood type, you can donate to B and AB, however if you are AB, you can only donate to AB.

Who Can You Receive Blood From?

If you are O blood type, you can only receive from O. If you are A, you can receive from type A and O. If you are blood type B, you can receive from type B and O. If you are AB, you are lucky, you can receive blood from O, A, B, and AB.

There are more than 600 other known antigens, the presence or absence of which creates "rare blood types". Certain types are unique to specific ethnic or racial groups, this is why an African-American blood donation can be the best hope for the needs of patients with sickle cell disease, as per the Red Cross Organization.

Universal Blood Donor

Type O is one in high demand, as it can donate blood to anyone. O negative blood type is the universal blood type, which can donate to everyone, especially during the emergency transfusions and for immune deficient infants.

Who Have These Blood Types In US?

In the US, 37% Caucasian, 47% African-American, 39% Asians, and 53% Latino-American are O-positive. However, only 8% of Caucasian, 4% of African-American, 1% Asian, and 4% Latino=Americans are O-negative.

A+: 33% Caucasian, 34% African-American, 27% Asian, 29% Latino-American

A-: 7% Caucasian, 2% African-American, .5% Asian, 2% Latino-American

B+: 9% Caucasian, 18% African-American, 25% Asian, 9% Latino-American

B-: 2% Caucasian, 2% African-American, .4% Asian, 1% Latino-American

AB+:3% Caucasian, 4% African-American, 7% Asian, 2% Latino-American

AB-: 1% Caucasian, .3% African-American, .1% Asian, .2% Latino-American

In early January, the U.S. Centers for Disease Control and Prevention (CDC) made one of the most significant changes to childhood vaccination policy in decades. Routine vaccination is no longer universally recommended for six diseases, including rotavirus, influenza, meningococcal disease and hepatitis A. The move follows a directive from President Donald Trump’s administration to reassess vaccine schedules and align them with what officials called “international consensus.”

Supporters of the change describe it as a step toward informed consent and transparency. Many public health experts see it very differently. They argue that the science behind the decision is selective, the process breaks with long-standing norms, and the consequences may only become clear years later.

So are these vaccines actually necessary, and is removing them from compulsory recommendation a reasonable move? Health and Me ran a fact check to see whether the four vaccines removed from the CDC universal guidelines would actually be a "better thing", as the Health Secretary and long time vaccine critic Robert F Kennedy Jr says.

Read: Children Getting Fewer Vaccine May Be A 'Better Thing', Says RFK Jr, As US Struggles With Rise In Flu Activity

What Exactly Changed With The CDC Vaccination

Until recently, the CDC recommended routine childhood vaccination against 17 diseases. That number has now dropped to 11. Vaccines for rotavirus, influenza, meningococcal disease, hepatitis A, hepatitis B and COVID-19 are no longer universally recommended for all children. Instead, they fall under shared clinical decision-making, meaning parents can still opt for them after discussion with a healthcare provider.

Importantly, this does not mean the vaccines are banned or unavailable. Insurance coverage remains largely unchanged for now, and vaccines remain recommended for children at higher risk.

The larger concern raised by experts is not access, but messaging. Universal recommendations have historically been one of the strongest drivers of vaccine uptake.

Read More: CDC Vaccine Schedule: Coverage Falls From 17 to 11 Diseases For Children

A Break From the Usual Scientific Process

Traditionally, changes to the U.S. vaccine schedule go through the CDC’s Advisory Committee on Immunization Practices, a panel of independent experts who review evidence publicly over months. This time, that process was bypassed.

Instead, the decision relied on a 33-page internal assessment prepared by two political appointees. Several experts criticized both the lack of transparency and the narrow interpretation of evidence.

Dr. Paul Offit, a pediatrician and vaccine expert at Children’s Hospital of Philadelphia, described the process as federal officials making sweeping decisions behind closed doors, without public input or broad expert review.

Rotavirus: Rare Deaths, Heavy Hospital Burden

Rotavirus causes severe diarrhea and vomiting in infants and young children, often leading to dehydration. Before routine vaccination began in 2006, an estimated 55,000 to 70,000 U.S. children were hospitalized each year due to rotavirus.

The administration justified dropping the universal recommendation by emphasizing low mortality rates. However, CDC researchers previously estimated 20 to 60 deaths annually in the pre-vaccine era. Experts say focusing narrowly on death counts ignores the very real suffering and healthcare burden the virus caused.

Offit, who helped develop one of the vaccines, noted that most pediatric residents today have never seen a child hospitalized with severe rotavirus dehydration. That absence, he argues, is proof of success, not irrelevance.

Meningococcal Disease: Rare but Devastating

Meningococcal disease is uncommon, but when it strikes, it can be deadly within hours. Even with treatment, about 15 percent of patients die, and up to 20 percent suffer permanent complications such as amputations or hearing loss.

The administration cited low incidence and World Health Organization thresholds to justify removing the universal recommendation. But experts counter that low incidence is precisely what vaccination programs aim to achieve.

Dr. David Stephens of Emory University pointed out that most high-income countries still recommend meningococcal vaccines, even with similarly low disease rates. He also warned that recent U.S. data show a resurgence, with 2024 recording the highest number of cases in over a decade.

Modeling studies suggest that U.S. vaccination programs have already prevented hundreds of cases and dozens of deaths. Removing universal recommendations, experts warn, risks reversing those gains.

Influenza: The Limits of Clinical Trials

Annual flu vaccination for children has been recommended since 2008, based on evidence that children both suffer from influenza and play a major role in spreading it.

The administration argued that randomized controlled trials have not proven flu vaccines reduce hospitalizations or deaths in children. What it did not emphasize is that such trials are not designed to detect rare outcomes like death.

Dr. Mark Loeb of McMaster University explained that proving mortality benefits would require trials involving millions of children, which is not feasible. Instead, real-world observational studies are used.

Those studies consistently show that flu vaccination reduces hospitalizations in children. A 2024 review in the New England Journal of Medicine estimated a 67 percent reduction in pediatric hospital admissions. Experts say dismissing this evidence reflects a misunderstanding of how vaccine effectiveness is measured.

Also Read: RSV Vaccine Has Benefits, Reveals Study Amid CDC's Changed Guidelines On Childhood Vaccines

Hepatitis A: Protecting Others by Vaccinating Children

Hepatitis A rarely causes severe illness in young children, which is precisely why childhood vaccination works. Children often spread the virus silently to adults, who face much higher risks of liver failure and death.

Dr. Noele Nelson, a former CDC epidemiologist, explained that vaccinating children interrupts this transmission chain and provides lifelong immunity. She warned that reducing childhood vaccination could recreate the conditions that once fueled adult outbreaks.

Claims that hepatitis A vaccines lack adequate safety data were also disputed. Clinical trials and decades of post-licensure monitoring have found no unexpected safety concerns, according to Nelson and other experts.

Are These Changes Scientifically Justified?

Public health experts broadly agree that these vaccines are not perfect and that honest discussions about risks and benefits matter. Where they strongly disagree is the idea that low disease rates or ethical limits on trial design justify weakening universal recommendations.

Low incidence, experts emphasize, is not a reason to stop vaccinating. It is evidence that vaccination works.

Whether the consequences of this policy shift emerge in five years or ten, many experts fear the costs will be paid quietly, through preventable hospitalizations, outbreaks and deaths that no longer make headlines but never needed to happen in the first place.

A GP has shared an urgent alert about a clearly visible cancer symptom that many women may be brushing aside. The doctor stressed that this particular sign needs to be checked without delay. Ahead of Cervical Cancer Prevention Week, beginning January 19, as per Mirror, Dr Rupa Parmar outlined key warning signs of the disease and cautioned that one in three women are skipping their routine cervical screening appointments.

She also highlighted that some of the most common symptoms are often dismissed. One such sign is weight loss, which many women may wrongly link to cutting back after festive overindulgence or returning to a normal routine in January.

Women Urged Not To Ignore This Obvious Cancer Symptom

Dr Parmar, a GP and Medical Director at Midland Health, explained: “Cancer cells interfere with the body’s ability to properly absorb fats, proteins and carbohydrates from food. As a result, calories are burned more quickly, leading to weight loss. Unexplained weight loss is often the most obvious sign of cancer and should always be checked straight away.” She added that sudden weight loss is not exclusive to cervical cancer and is recognised as a general warning sign across several types of cancer.

Cancer Research UK also notes that weight loss is common among people with cancer and can be one of the first reasons someone seeks medical advice. The charity points out that lung cancer and cancers of the upper digestive system are among those most often linked to weight loss.

Dr Parmar also highlighted other possible signs of cervical cancer.

Pain During Sex

Pain during intercourse can be caused by issues such as vaginal dryness, infections or skin conditions, Dr Parmar said. However, if pain is new and wasn’t present before, it could be linked to cervical cancer, as a growing tumour may begin to affect nearby tissues.

Recurrent UTIs

Experiencing three or more urinary tract infections within a year could indicate an underlying problem, including cervical cancer. Dr Parmar clarified that UTIs do not cause cancer, but repeated infections may occur if a tumour has advanced and is pressing on or blocking the urinary tract.

Pelvic Pain

Ongoing and severe pain in the lower back or pelvic area with no clear explanation can be another warning sign, particularly when combined with other symptoms. As cervical cancer advances, this pain may intensify and can worsen during sex, urination or bowel movements.

Vaginal Bleeding

Bleeding that is unusual for you should never be ignored. This includes bleeding during or after sex, spotting between periods, bleeding after menopause, heavier-than-normal periods, or cycles that last longer than usual. These changes can signal that something may be wrong.

Discharge

Changes in vaginal discharge can also point to problems with the cervix. An increase in discharge, an unusual smell, changes in colour, or the presence of blood may occur once cancer has begun to affect nearby tissues.

If you notice any of these symptoms, it’s important to speak to a doctor as soon as possible.

Dietary supplements are already part of many people’s daily habits, especially at the start of the year when health goals are front of mind. What many may not realise is that there is one supplement the Government says everyone should be taking through the colder months. Health guidance recommends a small daily dose of vitamin D for everyone in the UK from around October to late March, as sunlight levels are too low for the body to produce enough on its own. Vitamin D supplements are easy to find and come in several forms, including tablets, capsules, gummies and liquid drops. Here is a simple breakdown of what vitamin D is and why it matters.

What Is Vitamin D?

Vitamin D is an essential nutrient that helps control calcium and phosphate levels in the body. These minerals work together to support healthy bones, teeth and muscles.

When vitamin D levels are too low, children can develop rickets, a condition that causes bones to become soft and weak. In adults, deficiency may lead to osteomalacia, which can result in bone pain, muscle weakness and a higher risk of fractures.

What Does The Government Recommend?

UK health advice states that everyone should take a daily supplement containing 10 micrograms, or 400 international units, of vitamin D during autumn and winter.

This amount is considered sufficient to maintain general wellbeing, particularly bone and muscle health, at a time of year when sunlight alone is not enough for vitamin D production.

Official guidance explains: “This advice is particularly important for people who have little exposure to sunlight during spring and summer, including those living in residential or nursing care homes, people in prisons, and individuals who regularly wear clothing that covers most of their skin when outdoors.

“These groups are at greater risk of vitamin D deficiency. People with darker skin tones, such as those from African, African-Caribbean or South Asian backgrounds, may also struggle to get enough vitamin D from sunlight alone.

“All of these groups are advised to take a vitamin D supplement throughout the year, in line with standard government dietary guidance.”

A scheme that once allowed eligible people to apply for free vitamin D supplements was available previously, but this programme ended in 2021.

Where Can You Get Vitamin D?

Between late March or early April and the end of September, most people can produce enough vitamin D naturally through sun exposure. The body creates vitamin D when UV-B rays from sunlight reach the skin.

Vitamin D is also present in certain foods, including oily fish, red meat, egg yolks, and fortified products such as some spreads and breakfast cereals.

Supplements can be bought easily from pharmacies and supermarkets, with some costing as little as 2p per day. Vitamin D3 is generally the preferred form.

Can You Get Too Much Vitamin D?

Yes. While sunlight does not cause vitamin D overdose, taking excessive supplements over a long period can lead to a build-up of calcium in the body. This can weaken bones and cause damage to the kidneys and heart.

For most people, a daily intake of 10 micrograms is sufficient. NHS advice states that adults should not take more than 100 micrograms, or 4,000IU, per day, as higher amounts may be harmful.

If a doctor has advised a different dosage based on your individual health needs, it is important to follow their guidance.