It seems like winter has become a gauntlet of illness, between colds, flu, COVID-19, and norovirus, it can be impossible to remain healthy. However, knowing these illnesses, their symptoms and the ways in which they spread may help you ride out the season more effectively. Here's a closer look at these winter ills and some proactive measures you can take to protect yourself and your family.

Though viruses are present all year round, winter creates the perfect storm of infections. According to scientists, this uptick is due to more time spent indoors and the cold, dry air weakening our immune defenses. Respiratory and stomach viruses thrive under these conditions, making it vital to distinguish between them for effective care and prevention.

Experts have noticed that the pattern of respiratory illnesses has changed since the COVID-19 pandemic. High-level simultaneous spread of flu, RSV, and COVID-19 has been observed, making it a challenging phenomenon for health care systems.

Winter illnesses are very overwhelming, but some basic steps like hand washing, disinfecting surfaces, and getting vaccinated can make a lot of difference in keeping yourself and others safe. If you are feeling unwell, just stay home, rest, and seek the opinion of a healthcare provider if your symptoms worsen.

Spot the Difference Between All Symptoms

Each illness has its own signs, and the following can be seen to point towards the disease.

Norovirus

Often termed as "stomach flu," norovirus spreads by contaminated food, water, or surfaces. Its symptoms include nausea, vomiting, diarrhea, and stomach pain and last 1–3 days.

Common Cold

Caused by viruses, common colds are generally marked by a runny nose, congestion, coughing, sneezing, and sometimes low-grade fever. Its symptoms typically take a week to resolve.

Flu (Influenza)

It can cause sudden onset and symptoms like fever, chills, body aches, cough, and fatigue and may last for up to two weeks.

COVID-19

Its symptoms overlap with flu but might include shortness of breath, loss of taste or smell, and fatigue. Duration varies, but the symptoms could be several days or more.

RSV (Respiratory Syncytial Virus)

Common in children but increasingly affecting adults over 50, RSV can cause runny noses, coughing, sneezing, and wheezing, persisting for one to two weeks.

If you’re unsure about your illness, testing can provide clarity, especially for COVID-19 and flu, which have specific treatments available.

Also Read: Is US Preparing For A Quad-Demic 2025?

Why Hand Hygiene is the Most Important?

Viruses spread through contact with contaminated surfaces or droplets from coughs and sneezes. One of the easiest things to do to prevent this is by washing your hands frequently with soap and water.

Scour your hands for at least 20 seconds and be sure to clean every area, such as under the nails and between the fingers, for maximum cleanliness. When soap is not available, a hand sanitizer containing at least 60% alcohol is effective against most germs, though it won't kill norovirus.

Clean your high-touch surfaces regularly, such as doorknobs, light switches, and cell phones. For norovirus, disinfect contaminated surfaces with chlorine bleach solutions. Do not forget to wash clothes or linens that may have come into contact with bodily fluids in hot water and detergent.

Key Preventive Measure To Take When You Are Sick

Prevention is the best strategy against these diseases. Masks, especially N95 or medical-grade ones, reduce exposure to respiratory viruses in crowded or enclosed spaces. Being up to date on COVID-19 boosters, annual flu shots, and RSV vaccines (for those eligible) significantly reduces the severity of infections. Lastly, don't touch your face because touching it introduces germs on your hands into your body.

Your immune system works best when well-rested. Sleep deprivation, stress, and even dehydration weaken your defenses. Prioritizing sleep, managing stress, and staying hydrated can strengthen your body's ability to fight off infections.

Can People Get Both COVID-19 and flu or RSV and COVID-19 at the Same Time?

This winter marks another season of the "tripledemic," with flu, COVID-19, and RSV circulating simultaneously. Some patients are experiencing co-infections, with overlapping symptoms like fever, cough, and fatigue. While rare, these cases underline the importance of vaccinations and preventive measures.

If You're Sick, Should You Stay At Home And Rest Or See A Doctor?

If symptoms arise, appropriate measures can help you recover while preventing the spread to others. Staying home minimizes the risk of transmission. Hydration and rest support recovery, while over-the-counter pain relievers and humidifiers can ease symptoms. For norovirus, rehydration is crucial to combat the dehydration caused by vomiting and diarrhea. Seek medical help if symptoms worsen or persist.

As the seasons progress, remaining vigilant and proactive can help one navigate these tough months while securing health and wellness.

India has reported its second human fatality due to highly pathogenic avian influenza (HPAI) or bird flu, marking the first such death in four years. While bird flu infections in humans are rare, they are highly lethal, with a fatality rate of one in two cases. The most recent victim was a two-year-old girl from Palnadu, Andhra Pradesh, who passed away in mid-March after being hospitalized for over 10 days at the All India Institute of Medical Sciences (AIIMS), Mangalgiri.

The pathogen responsible for the infection and subsequent deaths was confirmed only on 31 March, following a survey by the Indian Council of Medical Research-National Institute of Virology (ICMR-NIV). According to details shared by the state government, the child, who had a habit of consuming raw chicken, was admitted to the hospital on 4 March with symptoms including fever, breathlessness, nasal discharge, seizures, diarrhea, and reduced feeding. Two days before falling ill, she had reportedly consumed raw chicken. She succumbed to the infection 12 days later.

In a statement issued on Wednesday, the state government noted that no abnormal cases of respiratory infections had been identified in the ongoing survey. However, surveillance will continue for the next two weeks, with testing arranged for any suspected cases. Union health ministry officials stated that, based on data from the Integrated Disease Surveillance Programme (IDSP), no unusual surge in influenza-like illness (ILI) or severe acute respiratory illness (SARI) cases has been observed in the district in recent weeks.

A national joint outbreak response (NJOR) team has been deployed to conduct an epidemiological investigation and provide assistance to the state.

3 States Impacted By Bird Flu

This year, outbreaks of HPAI—also known as Influenza A virus subtype H5N1 or bird flu—have been reported in Maharashtra, Karnataka, and Andhra Pradesh. The trend follows a similar pattern observed in 2024, when states such as Jharkhand and Kerala, along with the aforementioned three states, recorded widespread H5N1 infections in poultry, prompting authorities to cull thousands of birds.

The Union government emphasized that "human-to-human transmission of the H5N1 virus is uncommon, and the risk of any other epidemiologically linked case being reported is assessed to be low."

India's first recorded human infection of the H5N1 influenza virus occurred in 2021 when an 18-year-old boy in Haryana succumbed to the infection within days of contracting it.

In May last year, Australia reported its first human infection with H5N1, stating that the patient had acquired the virus in India. Towards the end of 2024, the deaths of four big cats—three tigers and a leopard—were attributed to H5N1 infection.

Oxytocin, commonly referred to as the "love hormone" because it is involved in bonding and social behavior, is now being investigated for its surprise effect on pregnancy. Although oxytocin is traditionally linked to childbirth, milk letdown during lactation, and emotional bonding, recent findings indicate that this hormone can possibly delay early pregnancy. A study on mice conducted recently has helped explain how the hormone can stop embryonic growth, which may provide new understanding of human fertility and pregnancy.

In a few mammals, such as marsupials, bats, and more than 130 others, a process called "diapause" takes place. This is a natural biological phenomenon that sees embryos suspend their development in order to wait until the right conditions prevail for pregnancy to resume. Although very uncommon and hard to monitor in human beings, clinical experience from in vitro fertilization clinics indicates that human embryos might at times show delayed implantation. One highly documented case in 1996 showed that an embryo implanted in a uterus was in a suspended state for five weeks before implantation took place.

The new research by scientists at the NYU Grossman School of Medicine investigated oxytocin's possible role in inducing this pause in pregnancy. Their results indicate that oxytocin could be a major player in controlling diapause in mice, and they raise questions about its possible role in human pregnancies.

Oxytocin-Induced Pregnancy Pause

To study the impact of oxytocin on pregnancy, scientists tested female mice who had recently given birth by letting them be mated while still lactating. The research revealed that nursing females had pregnancies that lasted about a week longer than those of the non-nursing mice. Since the normal pregnancy in mice takes only 19 to 21 days, this postponement is a drastic halt to embryonic development.

The research team then sought to determine how this pause occurred. Using optogenetics, a technique that enables the activation of specific neurons through light stimulation, they artificially triggered the release of oxytocin in pregnant mice. After five days of oxytocin stimulation, the researchers examined the mice’s uteruses and found that five out of six had embryos in a dormant state, indicative of diapause. Conversely, pregnant mice that were not administered oxytocin stimulation did not exhibit any indication of developmental arrest.

In further confirmation of their research findings, the scientists administered oxytocin to early-stage mouse embryos in the laboratory setting. They detected identical cellular alteration related to diapause, implying that oxytocin has a direct influence on suspended embryonic development.

How Oxytocin Affects Embryonic Development?

The research showed that oxytocin slows down the process through which embryonic cells convert genetic information into proteins. This process, essential for growth and development of the cell, is copying DNA instructions into RNA, which then guides protein synthesis. By suppressing this process, oxytocin puts the embryo into suspended animation.

Interestingly, scientists also learned that embryos without oxytocin receptors were still able to enter diapause, suggesting that more than one biological pathway is used to trigger the pause. Still, having working oxytocin receptors seemed to increase the embryo's chances of surviving the halted state. When oxytocin receptors in the embryos were deactivated, survival rates while in diapause fell to 11% from 42%.

Implications for Human Fertility and Pregnancy

Although this research is in its infancy, it presents exciting possibilities for human fertility studies. A better grasp of the role oxytocin plays during early pregnancy may lead to significant advances in treating unexplained infertility and recurrent miscarriage. If human embryos can enter a state of diapause, further study could reveal how hormonal or environmental influences are responsible for early pregnancy loss.

Also, these discoveries may have greater implications outside pregnancy. As oxytocin is implicated in cell survival, researchers now want to know if what it does in diapause can help understand how to keep nerve cells from dying in the developing nervous system. What stops cells from dying early on might help neurobiology and regenerative medicine advance.

Even with these thrilling findings, much remains to be answered. How long can diapause be in various species, including humans? What are other biochemical signals that cooperate with oxytocin to control embryonic development? And might this information one day lead to targeted fertility treatments or interventions?

More studies are needed to uncover these secrets. As researchers learn more about the multifaceted functions of oxytocin, its image as just the "love hormone" is changing. This potent molecule seems to play a much more intricate function in reproductive biology than has been known, and it may play a role not only in when life starts, but in when it temporarily gets suspended.

Oxytocin's role in pregnancy is turning out to be more complex than originally thought. Though still a primary force behind labor and maternal attachment, it has also recently been found to retard embryonic development, which could have far-reaching consequences for reproductive science. As more research unfolds, the hormone could provide new insights into fertility, enhance IVF success, and even prevent early miscarriage. The possibility of oxytocin-based fertility therapies is an exciting one, and future research will be important to determine how this information can be translated to human pregnancy.

A study published in the New England Journal of Medicine has listed five key factors that impact the longevity of individuals. The research tracked participants for up to 47 years, assessing how five specific factors influenced their risk of death, longevity, and the number of healthy years they could gain by altering these habits. The conclusions of this study were based on data analyzed from over two million adults aged 18 and above across 39 countries.

Five Factors That Influence Longevity

• High blood pressure
• High cholesterol
• Diabetes
• Smoking
• Bodyweight, including being overweight and underweight

Women Could Add 14 Years To Their Lives

As per the researchers, women who didn't have these five risk factors at age 50 could potentially add more than 14 years to their lives, and men could gain almost 12 additional years. Men were most affected by these factors as those with all five faced a 94% chance of dying before 90, while their counterparts without these issues had just a 68% chance. Women with all five risk factors at age 50 had an 88% chance of dying before 90, whereas those without these problems had a 53% chance.

Diabetes Is The Main Factor

Out of all the factors, cholesterol was the least impactful of all. As per the study, people who lowered their cholesterol levels could only add 1.2 extra healthy years to their lifespan. On the contrary, individuals who quit smoking could potentially extend their lives by up to six years. Women who do not have diabetes could gain an extra 6.4 years, while men without the condition might see an increase of 5.8 years. Even a slight reduction in blood pressure could lead to an additional 1.8 healthy years, and achieving a normal BMI could contribute an extra 2.6 years, with variations depending on the region.

Importance Of Lifestyle Changes

The study reinforces the importance of lifestyle modifications in extending a healthy lifespan. The researchers noted that small but consistent changes in daily habits could significantly impact longevity. For example, maintaining an optimal weight through a balanced diet and regular physical activity helps control blood pressure, diabetes, and cholesterol levels, reducing overall health risks.

Smoking cessation emerged as the most crucial lifestyle change that could dramatically influence lifespan. Quitting smoking, even later in life, significantly reduces the risk of cardiovascular diseases, lung disorders, and certain cancers, contributing to longer and healthier lives. Similarly, diabetes management through dietary changes, regular exercise, and proper medical intervention plays a vital role in preventing complications and enhancing longevity.

Regional And Gender-Based Differences

The study also highlighted variations in longevity gains based on gender and geographical regions. For instance, men were more susceptible to the adverse effects of these five risk factors than women. This disparity could be attributed to lifestyle differences, genetic predisposition, or healthcare access.

Additionally, in certain countries with high obesity rates, maintaining a normal BMI was one of the most significant contributors to longevity. Meanwhile, in regions with lower tobacco consumption, factors like high blood pressure and diabetes had a more prominent role in affecting lifespan.