Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

As winter transitions into warmer summer months, many people notice a sudden worsening of dandruff. During colder months, dandruff often appears as dry, fine flakes due to scalp dryness. However, as temperatures rise and humidity increases, dandruff can become oily and sticky because of increased sweating and sebum production. This seasonal shift highlights that dandruff is not limited to a particular time of year; rather, changes in climate can disrupt scalp balance and trigger flare-ups. Dr. Anupriya Goel, MBBS, MD, DPD (UK) – Dermatology, answered this for us.

Why does dandruff recur?

Many people struggle to understand why dandruff keeps recurring. It is often treated as a temporary cosmetic concern, but in reality, dandruff is a chronic scalp condition that requires consistent care and appropriate treatment. The primary cause of dandruff is a yeast called Malassezia globosa, which naturally resides on the scalp. This microorganism feeds on sebum (the natural oils produced by the scalp). As it breaks down these oils, it releases by-products that can irritate the scalp, leading to inflammation, itching, and visible flaking.

Seasonal factors further aggravate this process. In winter, cold air, low humidity, indoor heating, and frequent hot showers can strip the scalp of its natural moisture and weaken the skin barrier, resulting in dryness and flaking. In contrast, summer brings increased sweat and oil production. The combination of humidity, sweat, and sebum creates an ideal environment for Malassezia to multiply, which can worsen dandruff symptoms.

Read here: Simple Secrets To Establishing The Right Winter Hair Care Routine

What are the external factors responsible for dandruff?

Environmental factors such as pollution can also settle on the scalp and contribute to irritation. In addition, daily habits like wearing helmets for long hours, tying up damp hair, or not cleansing the scalp regularly can further disrupt scalp health. The transition period between seasons is often the most challenging, as the scalp has limited time to adapt to changing environmental conditions.

Because dandruff is often mistaken for a temporary issue, many people rely on occasional treatments or home remedies. However, effective management typically requires regular scalp-focused care using clinically proven active ingredients.

Treating dandruff

One such ingredient commonly used in anti-dandruff formulations is Piroctone Olamine, an antifungal agent that helps control the growth of Malassezia on the scalp. By reducing fungal proliferation, it helps address the underlying cause of dandruff and can assist in decreasing flaking, itching, and scalp irritation. It also helps cleanse the scalp by removing excess oil and buildup while being relatively gentle on the hair and scalp.

Read more: 7 Ayurvedic Hair Health Tips You Should Try For Healthy Locks

For optimal results, individuals experiencing recurrent dandruff may benefit from incorporating an anti-dandruff shampoo containing Piroctone Olamine into their regular hair care routine. Consistent use is important for maintaining scalp balance. During periods of increased sweating, such as in hot and humid weather, washing frequency may be increased as needed. Maintaining hygiene practices such as regularly cleaning helmets, pillowcases, and hair accessories can also help minimise recurrence.

In addition to controlling dandruff, well-formulated shampoos containing Piroctone Olamine are often combined with conditioning and moisturising ingredients that help maintain hair softness and scalp comfort while supporting long-term scalp balance.

Autism in women is not often entirely recognized because this disorder does not always have to correspond to the “classic” picture characteristic of males.

The diagnosis is based on a male criterion with such behavior as obvious withdrawal from a group, overtly displayed repetitive behaviour, and limited interests. There can be mild social deficit or internalized anger and frustration that can pass unnoticed in clinical practice.

The Art of Masking

One of the most significant reasons behind underdiagnosis is masking (also called camouflaging). Masking is one of the most significant reasons for underdiagnosis. This is helpful in masking but also covers or conceals essential symptoms.

Masking causes mental exhaustion, anxiety, and burnout, but it does not address the underlying autism and leaves it undiagnosed.

Stereotypes And Gender Bias

There is a strong societal stereotype that autism is a “male condition”. This bias is felt by parents, teachers, as well as health care professionals.

Sex bias is evident in that boys get referred for evaluation early. Girls are often tagged “shy,” “sensitive,” and “introverted.”

Their struggles are normalized instead of being explored for any issues. Gender bias is a significant contributor to delayed or wrong diagnosis.

Different Interests, Less Suspicion

A restricted interest is another hallmark of autism, but in women, it tends to be more socially acceptable. Their interests conform to the norms of society; they do not predispose clinical suspicion as opposed to more masculine interests like mechanical systems or numbers.

Overlap With Other Conditions

Autism in women being misdiagnosed as other psychiatric disorders is due to symptom comorbidity. Some of the common misdiagnoses are:

• anxiety disorders,
• major depressive disorder,
• borderline personality disorder,
• eating disorders.

In many cases, these are secondary to autism as a result of years of living with undiagnosed autism.

Social Expectations And Conditioning

From an early age, girls are often conditioned to be socially attentive, empathetic, and compliant. This societal conditioning pushes autistic girls to adapt and hide their difficulties.

These may include forcing themselves into socializing. Fitting in is deemed more important than comfort. They end up creating coping mechanisms that mask their difficulties.

While this may benefit outward functioning, it postpones the recognition of underlying neurodevelopmental differences.

The Consequences of Late Diagnosis

Delayed diagnosis or missed diagnosis has the following effects:

• Chronic mental illness
• Low self-esteem
• Confusion about identity
• Inadequate support services

The World Health Organization estimates that 10 percent (190 million) of reproductive-age women worldwide suffer from endometriosis.

The chronic and complex menstrual disease that affects many women is characterized by severe pain during menstruation, heavy menstrual bleeding, chronic pelvic pain (pain that does not go away when the menstrual cycle ends), infertility, and abdominal bloating and nausea.

The incurable condition poses a significant challenge to women as it affects their personal and professional lives, relationships, and fertility, among others, due to persistent pain and fatigue.

The diagnosis also gets delayed, as endometriosis is often confused with PCOS, or Polycystic Ovary Syndrome, due to some overlapping symptoms like irregular menstrual periods. The symptoms may continue to persist or recur after treatment is initiated.

In a powerful statement resonating with millions worldwide, Indian American author and television host Padma Lakshmi has shared her experience with the condition.

Opening about her personal battle with endometriosis, the 55-year-old, Co-founder of Endometriosis Foundation of America, said that the condition made her understand how strong she is and called for greater awareness and self-advocacy among women.

"Endometriosis has taught me that I should always listen to my body. Pain is your body's way of telling you something is wrong,” said Lakshmi, in a media post on social media platform Instagram.

"Through my struggles with endometriosis, I've learned that, actually, I have a very high threshold for pain, that I may be stronger than I know, but that I shouldn't always need to be,” PopSugar quoted her as saying.

Lakshmi noted that it is now her life's mission "to advocate for my own health, and also to advocate for all women with endometriosis."

What Is Endometriosis?

Endometriosis happens when tissue similar to the lining of the uterus grows outside the uterus. These tissues commonly develop on the ovaries, fallopian tubes, or the pelvic lining.

Endometriosis affects many women and can impact their daily lives, including their ability to work comfortably. Many women continue their professional responsibilities despite experiencing severe discomfort, fatigue, and pain.

Raising awareness about the condition and encouraging supportive workplaces can help women manage both their health and career more effectively.

Since it is a progressive disorder, timely intervention remains key to managing it. In many cases, women live with symptoms for several years before receiving the correct diagnosis, which can delay treatment and affect their quality of life.

Treating Endometriosis

Treatment is particularly based on the severity of symptoms. Women will be advised lifestyle modifications such as regular exercise, stress management, and an anti-inflammatory diet. Non-steroidal anti-inflammatory drugs may help reduce discomfort.

Hormonal therapies may also be used to control symptoms. Some women will be advised to undergo laparoscopy to remove endometriotic cysts.

Minimally invasive surgery can help remove lesions and restore pelvic anatomy, which may also improve fertility in some cases. In advanced cases, surgery can be recommended to women.