What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Updated Dec 3, 2024 | 06:13 PM IST

SummaryDid you know type 3 diabetes, linked to insulin resistance in the brain, is associated with Alzheimer’s disease? It highlights how metabolic disorders can affect memory, cognition, and brain health.
What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

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Have You Lived This Moment Before? The Science Behind Déjà Vu

Updated Jun 15, 2026 | 09:00 PM IST

SummaryDéjà vu is a common sensation where a person feels they have already experienced a current moment before. Despite seeming rare, it occurs in most people at least once.
Have You Lived This Moment Before? The Science Behind Déjà Vu

Credit: AI Generated Image

Déjà Vu is a feeling of sensation when one person feels that they have felt or witnessed the same situation before, just like a single incident is happening once again. The word itself is from French and means "already seen." Though there is a common misconception among people that Déjà Vu is a very rare occurrence, in reality, this apparently mysterious experience happens to almost 97 percent of people's lives. Thus, it is a very common thing that will be felt by most people at least once in their lifetime.

What Is Déjà Vu?

As mentioned before, the word itself shows the very aspect of Déjà Vu that it's already seen. Suppose you are having a deep conversation with your friend, family, or a stranger, but you feel like this is not the first time you are having this conversation; you already know the topics and outcomes, as if you are living the same moment that you have lived before.

On the other hand, you might be visiting a new place, maybe a new city that you have never visited, but the places, houses, and overall atmosphere feel very recognizable. You suddenly feel that you have visited that place before and have felt good or bad in the past, as if you are living a past in your present.

All in all, this kind of strange phenomenon that happens to people regularly, this kind of uncomfortable feeling which is felt by 97 percent of people in the world, is called Déjà Vu.

What Causes Déjà Vu?

The root cause of this strange phenomenon is believed to be a result that one place or any conversation or any situation is resembling the same kind of pattern or feelings that you have experienced and felt before, and in most cases, you yourself have forgotten that, but your brain has not, and it recreates this sense of familiarity, and you feel you are living in a paradox.

In other words, déjà vu occurs when two parts of your brain fail to communicate properly: the temporal lobe, which handles memories, and the hippocampus, which processes new experiences.

There are certain things that can cause Déjà Vu more than others, such as fatigue or sleep deprivation, stress, and anxiety, which can trigger the feeling of Déjà Vu, as this pressure on your mental and physical health might pressure your brain and distort the recognition process. Other than that, migraine, dementia, and seizure can also cause Déjà Vu in a person.

Occasional déjà vu is generally harmless and not a cause for concern. However, if it happens frequently, lasts more than a few seconds, or is accompanied by other symptoms, it may be a good idea to seek medical advice.

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Why Sleeping Pill Addiction Is Common Among Football Players

Updated Jun 15, 2026 | 07:00 PM IST

SummaryDr. Chandran, currently President of the Indian Federation of Sports Medicine (IFSM), said that while players may turn to sleeping pills as a quick solution, regular use can become a habit that leads to dependence if left unchecked.
Why Sleeping Pill Addiction Is Common Among Football Players

Credit: AI generated image

As the FIFA World Cup 2026 is underway, players are navigating demanding training schedules, frequent travel, challenging weather conditions, and the pressure to perform at their peak. Amid these challenges, many elite footballers quietly face an often-overlooked problem off the field: sleep disturbances.

In an exclusive interview with HealthandMe, Dr. P.S.M. Chandran, former Director of Sports Medicine at the Sports Authority of India (SAI), said that the stress, anxiety, and disrupted routines associated with elite sport can make it difficult for players to get adequate rest. In some cases, these challenges may drive athletes toward sleeping medications, potentially affecting both their health and on-field performance.

Dr. Chandran, currently President of the Indian Federation of Sports Medicine (IFSM), said that while players may turn to sleeping pills as a quick solution, regular use can become a habit that leads to dependence if left unchecked.

Recently, striker Omar Bogle, who plays for Crewe Alexandra in League Two, shared his story with The New York Times' The Athletic about the moment last year when he became addicted to sleeping pills and painkillers.

What began as a way to help him sleep after suffering a back fracture during pre-season in the summer of 2024 became an addiction.

From January 2025, his usage accelerated to an alarming level. He said that many of the pills he was taking were benzodiazepines, such as diazepam and lorazepam. He was also using the stronger zopiclone pills, which the NHS says can be prescribed for the short-term treatment of severe insomnia.

"No one knew the extent of what I was doing," he said. "I never told anyone I was popping 18 or 19 of the things in the night."

Bogle's is not alone.

Also read: FIFA World Cup 2026: What Keeps Messi and Ronaldo Biologically Younger Than Their Age? Experts Explain

In January 2026, former England midfielder Jonjo Shelvey revealed on a podcast how he had become addicted to sleeping pills because of the loneliness he experienced while playing in Turkey. Shelvey said his dependence affected his relationship with his children.

Former Manchester United midfielder Darron Gibson also developed a sleeping pill addiction and, at his worst point, was taking 12 to 14 tablets a night, according to The New York Times.

In 2023, former Tottenham Hotspur and England midfielder Dele Alli told the BBC that he had become addicted to sleeping pills to block out past traumas.

According to Dr. Chandran, the issue is not unique to football but affects athletes across multiple sports, driven by stress, performance pressures, injuries, and demanding schedules.

"Football is not an exception," Dr. Chandran said. "Because of its popularity, we hear more about football players, but athletes in other sports face similar problems."

Why Elite Footballers Face Sleep Issues?

Elite footballers operate in a high-pressure environment where careers can be influenced by contracts, team selection, injuries, and performance expectations. Frequent travel, changing time zones, training camps, and irregular eating patterns can further disrupt normal sleep cycles.

According to Dr. Chandran, these factors create significant psychological stress, making it difficult for athletes to unwind and get adequate rest.

"Athletes are always stressed because of their contracts with clubs, their interaction with coaches, and concerns about injuries that can affect their income," he explained. "All these tensions bring stress, and stress leads to sleep disturbance."

Read More: Heading to FIFA World Cup 2026? Here's How to Stay Safe From Measles, Heatstroke

Why Athletes Turn to Sleeping Pills

Sleep plays a crucial role in athletic recovery. Without adequate rest, muscle repair, mental focus, and physical performance can suffer.

"If athletes do not get good sleep, the next day's training will suffer," Dr. Chandran said. "To get better sleep, they try sleeping pills. That becomes an escape route for them."

However, he warned that regular use of sleeping medications can quickly develop into dependence.

"Once they start taking sleeping pills, it becomes a habit. It is difficult to get out of it," he told HealthandMe.

The expert noted that while occasional use under medical supervision may be appropriate in certain situations, unsupervised and prolonged use can worsen sleep problems and lead to dependence.

Also read: 22 Treated For Heat Illness At FIFA Fan Festival: How Are World Cup Players Protected?

The Role of Stress Hormones

Stress hormones such as cortisol, adrenaline, and noradrenaline are naturally involved in exercise and performance. However, elevated stress levels can interfere with healthy sleep patterns.

These hormones increase alertness, heart rate, and metabolic activity—responses that may be useful during competition but can make it difficult to fall asleep afterward.

Dr. Chandran emphasized that athletes should seek professional guidance when dealing with sleep issues rather than relying on self-medication.

Recovery Is Key to Performance

Modern sports science places a strong emphasis on recovery, recognizing it as an essential component of performance. Elite football clubs now employ teams of physiotherapists, psychologists, nutritionists, doctors, and recovery specialists to help athletes maintain optimal health.

"Training leads to tiredness, and tiredness has to be overcome by recovery methods," Dr. Chandran said. "The better you recover, the better you can perform the next day."

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Implant Dentistry Beyond Replacement: How It Restores Quality of Life

Updated Jun 15, 2026 | 06:00 PM IST

SummaryBy restoring the ability to eat, speak, smile, and engage confidently in daily life, implant dentistry offers benefits that extend far beyond the replacement of a missing tooth.
dental implant (1)

As awareness of the broader benefits of implant therapy continues to grow, dental implants are increasingly being recognised as a comprehensive rehabilitation solution. (Photo credit: AI generated)

The loss of a tooth is often viewed as a purely dental concern, but its impact extends far beyond appearance. Missing teeth can affect chewing efficiency, speech, facial structure, and even emotional well-being. While traditional tooth replacement options have served patients for decades, modern implant dentistry has transformed the way tooth loss is managed. Today, dental implants are not merely about filling a gap; they are about restoring function, confidence, and overall quality of life.

Restoring Natural Function and Comfort

Dr. Achuth M. Baliga, Director, Happiest Pearls, said, "One of the greatest advantages of dental implants is their ability to closely replicate the function of natural teeth. Unlike removable dentures that may shift or cause discomfort, implants are anchored securely within the jawbone, providing exceptional stability. This allows individuals to chew a wider variety of foods with confidence and comfort."

The expert went on to say that proper chewing is essential for nutrition and digestive health. Patients who struggle with missing teeth often avoid certain foods such as fruits, vegetables, nuts, and proteins, potentially compromising their dietary intake. By restoring full chewing efficiency, dental implants help individuals maintain a balanced and nutritious diet, contributing to better overall health. Dr Baliga also answered more FAQs on the subject.

Preserving Jawbone and Facial Structure

Tooth loss triggers a process known as bone resorption, where the jawbone gradually deteriorates due to the absence of stimulation from the tooth root. Over time, this can lead to changes in facial appearance, including a sunken or prematurely aged look.

Dental implants address this challenge by functioning like artificial tooth roots. They stimulate the surrounding bone during everyday activities such as chewing, helping to preserve bone volume and density. This not only supports long-term oral health but also helps maintain natural facial contours. In many cases, implants play a significant role in preserving a youthful appearance and preventing the structural changes associated with prolonged tooth loss.

Rebuilding Confidence and Self-Esteem

The psychological effects of missing teeth are often underestimated. Individuals may become self-conscious about smiling, speaking, or interacting socially. Concerns about appearance can affect personal relationships, professional interactions, and overall self-confidence.

Dental implants provide a fixed and natural-looking solution that blends seamlessly with surrounding teeth. The ability to smile without hesitation and speak without worrying about movement or instability can have a profound impact on emotional well-being. Many patients report feeling more confident in social settings and more comfortable expressing themselves after completing implant treatment.

Supporting Better Speech and Daily Living

Missing teeth, particularly in the front of the mouth, can interfere with pronunciation and speech clarity. Similarly, loose or ill-fitting dentures may cause slurring or difficulty articulating certain sounds.

Because implants are securely integrated into the jawbone, they provide the stability needed for clear and natural speech. Everyday activities such as eating in public, participating in meetings, or engaging in conversations become more comfortable and predictable. These seemingly small improvements can significantly enhance daily living and social participation.

Advancements Making Treatment More Predictable

Modern implant dentistry has benefited greatly from technological innovations. Digital imaging, three-dimensional treatment planning, guided implant placement, and advanced restorative materials have improved precision and predictability. These advancements allow clinicians to tailor treatment plans to each patient's unique anatomy and functional requirements.

In addition, improved understanding of bone biology and soft tissue management has contributed to higher success rates and more aesthetically pleasing outcomes. As a result, implant therapy has become a reliable long-term solution for a wide range of patients experiencing tooth loss.

A Comprehensive Approach to Oral Health

Implant dentistry today is centred on patient outcomes rather than simply replacing missing teeth. The goal is to restore oral function, maintain facial structure, support emotional well-being, and improve overall quality of life. Successful treatment considers not only the clinical aspects of tooth replacement but also the patient's lifestyle, expectations, and long-term health needs.

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