Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

Mental health struggles among young children and teens are most likely to get overlooked due to many reasons. That is one of the glaring problems that prompted 16-year-old Imaan Zara Khan to write and direct Unspoken, a movie that follows four teenagers from different social, cultural, and economic backgrounds who navigate their mental health struggles.

Imaan told HealthandMe, "We constantly tell young people to speak up, but what happens when they don’t have the words for what they’re feeling? And even when they do, there’s the fear of being judged, misunderstood or simply not taken seriously. The social visibility cost is simply too high. So, they choose silence instead. I wanted to explore that silence, because sometimes the biggest barrier to seeking help comes long before someone actually asks for it."

The Ministry of Education, Government of India, recently reviewed the draft school mental health policy to foster students' mental wellbeing. The landmark move aims at ensuring adequate resources to protect students' mental well-being by strengthening school systems. Scaling up proven best practices to promote student mental health and psychosocial well-being is one of the primary objectives of the policy.

On World Mental Health Day, we review the government's initiative to comprehend its importance and urgency amid expanding mental health crisis in India's young population.

School Mental Health Policy Aims To Reshape Mental Care For Young Children

Also read: Childhood Fitness Linked To Lower Risk Of Depression In Adulthood: 30-Year Study

The policy entails several key measures to reshape mental healthcare in educational institutions. From identifying early signs of academic stress to proactive screening, it says that schools must routine mental wellness checkups into their academic calendars.

Nandita Bhatla, Vice President and Country Director, WorldBeing India, an international non-profit that works towards integrating mental health wellbeing programs into education systems, told HealthandMe, "India has done well to break the silence. Yet the loss of young lives to suicide tells us that too many children still feel they have nowhere to turn, and that listening cannot wait for a crisis."

She added, "The harder, more important work is making care a routine part of a school day, owned and led by governments, and not dependent on a single programme or a single champion. Schools are the lived reality of millions of our children. When they become spaces to build resilient, hopeful individuals and not mere academic achievers, we know we are on the right path."

The draft also stresses upon building an inclusive and supportive school culture built on a strong foundation of empathy, care, and mutual trust.

The policy also moves away from emergency crisis management. Instead, it aims to create robust, long-term support systems that could help children thrive and stay motivated towards building their future.

Imaan said mental health problems should not be treated as emergencies. She said, "Just as we build physical health through everyday habits, schools should be building emotional resilience, coping skills and mental-health literacy from an early age. But equally important is having a clear, transparent, end-to-end framework that everyone, whether it’s a student, teacher or parent, can understand and navigate."

Also read: Over 2 Hours of Daily Screen Time Linked to Depression, Obesity In Young People: Lancet

Turning Teachers Into Mentors

The policy also focuses on training teachers to be primary mentors for students who could interact with them every day and recognise early signs of conditions like stress, anxiety, and depression. According to the policy, teachers will be trained to identify changes in behaviours and academic burnout.

This does not mean that teachers will replace professional counselors. Additionally, this effort also urges parents to monitor domestic environments.

The policy also plans to channel traditional Indian Knowledge Systems to promote mental wellness among students. It urges schools to integrate mindfulness practices into everyday student activities.

It promotes that these ancient practices can equip students to handle academic pressure, especially during stressful board examinations. The updated curriculum will now support both cognitive growth and development and psychological well-being.

Artificial intelligence is changing the way people work. Tasks that once required hours of effort can now be completed in minutes; therefore, organizations are increasingly using AI tools to improve productivity, reduce costs, and streamline operations. These changes have brought both excitement and fear along with them. That is, will my skills still matter in the future?

The fear of becoming irrelevant in an AI-driven workplace is becoming a source of anxiety for employees across industries. Beyond concerns about job security, many are struggling with the pressure to learn new technologies, keep up with changing expectations and prove their value in an environment where machines are becoming increasingly capable.

The Pressure To Prove Oneself

Workplace anxiety surrounding AI does not always stem from the possibility of losing a job. Sometimes, it comes from the feeling that one must constantly do more to remain employable.

Employees who have spent years developing expertise in a particular field may find it unsettling to see AI tools perform parts of their work in seconds. Writers, designers, analysts, customer service professionals and even experienced managers are being encouraged to adapt to new technologies, often while managing their existing responsibilities.

For some, this creates a persistent sense of falling behind. Learning new tools becomes less about professional growth and more about avoiding obsolescence. The pressure can be particularly challenging when employees are uncertain about which skills will remain valuable or how quickly their roles might change.

Professionals’ Fear Of Uncertainty Affects Mental Health

Prolonged uncertainty about one's career can affect emotional well-being. Employees may experience stress, irritability, difficulty concentrating, disrupted sleep or a loss of confidence in their abilities. Some may begin comparing their productivity with AI-generated outputs, overlooking the judgement, experience and context they bring to their work.

There is also the pressure to demonstrate constant productivity. When technology makes it possible to complete tasks faster, employees may feel expected to produce more within the same working hours. What initially appears to be a tool for reducing workloads can, in some workplaces, create an expectation of doing more with less time.

Over time, this pressure can contribute to exhaustion and burnout, particularly when employees have little control over how new technologies are introduced or how their performance is measured.

However, not everyone experiences AI in the same way. Some employees welcome the opportunity to learn, experiment and move away from repetitive tasks. The impact often depends on individual circumstances, workplace culture, access to training and the level of uncertainty surrounding employment.

The Importance Of A Supportive Workplace

Employers have an important role to play in reducing unnecessary anxiety during technological transitions. Introducing AI without explaining its purpose can leave employees filling information gaps with their own fears.

Clear communication about how AI will affect specific roles, what changes employees can expect and which skills they should develop can help reduce uncertainty. Training should be accessible and practical, allowing employees to learn without feeling that they must master every new tool immediately.

Managers should also recognize that productivity is not the only measure of an employee's contribution. Critical thinking, creativity, communication, ethical judgement and the ability to understand people remain important aspects of professional work.

Creating opportunities for employees to ask questions, express concerns and participate in decisions about AI adoption can help build trust. Organisations should also pay attention to signs of excessive workload, disengagement and burnout rather than assuming that employees will automatically adapt.

Finding A Healthier Relationship With AI

For employees, it may help to approach AI as a skill to develop rather than a competition to win. Identifying the tools relevant to one's role, learning at a manageable pace and strengthening skills that complement technology can make change feel less overwhelming.

It is equally important to recognize that professional worth cannot be measured solely by speed or the number of tasks completed. Experience, sound judgement, empathy and accountability continue to shape meaningful work. If anxiety begins to interfere with sleep, daily functioning or relationships, seeking support from a mental health professional may be helpful.

AI will continue to change the workplace, but the transition does not have to come at the cost of employee well-being. Organizations that combine technological progress with honest communication, meaningful training and respect for their workforce are more likely to create environments in which people can adapt with confidence.

Ultimately, the question is not simply whether employees can keep pace with AI. It is whether workplaces can evolve in ways that allow people to feel secure, valued and capable of growing alongside it.

(By Shilpi Saraswat, Clinical Psychologist, Sakra World Hospital, Bengaluru)

Spending hours sitting at a desk, gaming or binge-watching shows without moving may increase the risk of blood clots, including deep vein thrombosis (DVT), vascular experts have warned.

Prolonged sitting slows blood flow from the legs, potentially increasing the risk of clot formation. Experts from the Vascular Society of India (VSI) highlighted the concern at the VSI-ASVS 2026 Conference, noting that sedentary screen habits warrant attention even among young, otherwise healthy people.

“In our OPD, we are seeing patients where lifestyle history has become an important part of the vascular evaluation. Earlier, when we thought about prolonged immobility, we primarily discussed long-distance travel, hospitalization or being bedridden. Today, we also need to ask young patients how many hours they spend continuously sitting in front of a gaming console, computer or OTT screen,” said Dr. Tarun Grover, Senior Director of Peripheral Vascular and Endovascular Sciences at Medanta.

What Is DVT?

Deep vein thrombosis (DVT) occurs when a blood clot forms in a deep vein, usually in the legs. If the clot travels to the lungs, it can cause a potentially life-threatening pulmonary embolism.

Although prolonged immobility has traditionally been associated with long-distance travel, hospitalization and bed rest, experts say extended screen time can also contribute to inactivity.

Gaming and binge-watching do not automatically cause DVT. However, prolonged sitting may add to the risk, particularly in people with obesity, dehydration, smoking habits, hormonal risk factors, inherited clotting disorders or a previous history of thrombosis.

Also read: Richard Branson’s Wife’s Death Highlights Blood Clot Risk After Fractures

What Does Science Say?

A 2024 systematic review and dose-response meta-analysis published in Scientific Reports, covering 25 articles and 31 studies, found that people with the highest levels of sedentary behavior had approximately 24% higher risk of venous thromboembolism (VTE) than those with the lowest levels.

The analysis also found a 2% increase in VTE risk for every additional hour of sedentary behavior per day. The association persisted after accounting for physical activity, suggesting that exercise may not fully offset the potential risks of prolonged sitting.

The experts explained that when people sit for hours, their calf muscles—which help pump blood back toward the heart—remain relatively inactive, slowing venous circulation.

A separate study of 11 adolescents with thrombosis found that all reported at least four hours of daily screen exposure, averaging approximately six hours. Eight had DVT in the legs, two had pulmonary embolism and one had subclavian vein thrombosis.

Many also had inherited thrombophilia, a predisposition to blood clots. Researchers noted that prolonged screen-related inactivity may act as an additional trigger rather than the sole cause of thrombosis.

“The evidence showing a 24% higher VTE risk with higher sedentary exposure should make us take this issue seriously. A young age should not create a false sense of security, particularly when prolonged sitting is combined with other risk factors,” Dr. Grover said.

How Can You Reduce The Risk?

Experts recommend taking regular movement breaks during work, gaming and streaming sessions to avoid prolonged uninterrupted sitting.

“Just as smoking increases vascular and clotting risks, prolonged sitting can also increase the risk of blood clots. When a person remains seated for hours, the calf-muscle pump becomes inactive, venous blood flow from the legs slows down and blood can stagnate in the deep veins," said Dr. Bhupesh Garg, Senior Vascular and Endovascular Surgeon, Vascular Society of India.

The message should be simple: if you are going to spend hours on a screen, do not spend those hours completely still, the experts said.