What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Updated Jun 7, 2025 | 11:15 AM IST

SummaryDid you know type 3 diabetes, linked to insulin resistance in the brain, is associated with Alzheimer’s disease? It highlights how metabolic disorders can affect memory, cognition, and brain health.
What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

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Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

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Have Dense Breasts? What Women Should Know About Their Breast Cancer Risk

Updated Sep 5, 2026 | 03:00 PM IST

SummaryDense breast tissue can increase breast cancer risk and make some cancers harder to detect on mammograms, making personalised screening discussions important.
Have Dense Breasts? What Women Should Know About Their Breast Cancer Risk

Credit: AI

Many women may come across the term "breast density" following a mammogram, but not all of them fully understand what it implies. The fact that someone has dense breasts does not mean that they have cancer or that they will definitely get it.

On the other hand, greater breast density can be linked to a higher risk of breast cancer and may also make it more difficult to detect certain cancers on a mammogram.

What Is Breast Density?

The breast density is the ratio of fibrous and glandular tissue to fatty tissue in the breast. Dense breast tissue is a normal variation and is especially frequent in younger women. It should be clear that women cannot tell themselves if their breast has dense tissue or not; it has to be assessed using breast imaging, typically a mammogram.

Breast density is usually divided into four types, going from almost all fatty tissue to very dense tissue, and women who have heterogeneously dense or extremely dense breasts are at a greater risk of developing breast cancer than women whose breasts are mainly fatty.

Also read: Alcohol-Linked Cancer Deaths Doubled In US: Colorectal Leads In Men, Breast Leads In Women

What Do Dense Breasts Indicate?

A major concern is that on a mammogram dense tissue appears white, just as many breast abnormalities—some of which are cancers—do too. This makes it harder for radiologists to spot certain abnormalities. Women need not be alarmed if their mammogram report states that their breasts are dense.

Breast density is just one of the factors to take into account when evaluating the risk of breast cancer; family history, age, past breast conditions, genetic mutations, hormonal factors, reproductive history, and lifestyle must also be considered.

It will depend on a woman's total risk level whether or not further screening is needed. Although mammography is still an important method of screening, in certain individual cases a doctor may suggest extra imaging, for example breast ultrasound or magnetic resonance imaging (MRI). Such tests are not required automatically for every woman who has dense breasts.

Also read: How Scientists Blocked Drug-Resistant Triple-Negative Breast Cancer With A Two-Step Drug Method

What Should Women Do?

Women should also know what is normal for their breasts. If a new lump is detected, there is a persistent change in the shape or size of the breast, the skin becomes dimpled, the nipple turns inwards, there is an unusual discharge from the nipple or there is ongoing discomfort, then it is advisable to have a healthcare professional look at it. Yet the majority of breast changes are not cancerous and symptoms by themselves are not enough to make a diagnosis.

Lifestyle plays a big role in maintaining breast health. One way of reducing the overall risk of breast cancer is to keep a healthy weight, remain physically active, limit alcohol intake, avoid tobacco, eat a well-balanced diet and stick to the recommended screening programmes.

Women must not regard breast density as a diagnosis. The main point is that women should not be afraid of dense breasts but should understand what this means for them. They must talk to their family doctor about their mammography report and their individual risk factors and then follow a screening programme suitable to their risk.

Breast density is therefore a valid reason for having a screening examination, not one for concern. By understanding breast density and talking to a breast specialist, women can make informed choices regarding screening and make sure that any potential abnormalities are assessed as early as possible.

By Dr. Meghal Sanghavi, Consultant Onco Surgeon, Wockhardt Hospital, Mumbai Central

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Teachers' Day 2026: How Teachers Shape Students’ Mental Health

Updated Sep 5, 2026 | 11:00 AM IST

SummaryTeachers can shape students’ mental health through supportive relationships, communication and safe classrooms. Research shows teacher well-being and experience can positively influence student well-being.
Teachers' Day 2026: How Teachers Shape Students’ Mental Health

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Teachers are unarguably one of the most important influences during the early stages of a person's life. Along with learning and wisdom, teachers can also influence a child's or adolescent's mental health. Thus, they help shape students who are the future of any society or nation. This impactful profession and its contributions are celebrated worldwide, including in India.

The deteriorating mental health condition in students has escalated into a major global public health concern, heavily accelerated by academic pressure, systemic changes, and digital isolation. The World Health Organization (WHO), UNICEF, and Indian governmental bodies like NCERT have shared data that reveals a grim situation: there is a huge gap between the rising psychological distress among youth and the infrastructure available to support them.

The role of teachers in youth mental health is a topic that the study "A Shelter for the Heart: The Impact of Teacher Quality on Students' Mental Health" has thoroughly analyzed. The research, published in the journal Health Economics in 2026, was conducted in China and included 3,529 Grade 7 students, 86 classrooms, and 43 schools throughout the country. The study examines the impact of teacher quality, proxied by teacher experience, on student mental health.

How Do Teachers Protect Students' Mental Health?

According to the study, the role of the head teacher is particularly important to a student's mental well-being. While subject teachers are primarily responsible for learning, the study emphasizes that experienced teachers might do more than improve grades—they may also help protect students' mental health.

The study finds that the more experienced head teachers tended to build stronger teacher–student relationships, communicate more with parents, and create more supportive classroom environments. They were less likely to ignore or isolate struggling students and more likely to try to help them. All in all, the researchers concluded that school environments play an important role in determining adolescents’ mental health.

Mental Health On Location And Gender

The study “A study on mental health of students teacher in relation to their achievement in education psychology” by researchers at Tamil Nadu Teachers Education University, Chennai, found significant differences in mental health based on gender and location, with female and rural student-teachers reporting better mental health than their male and urban counterparts.

Teacher Distress Linked To Student Mental Health

A 2024 study published in BMC Psychology by researchers from McMaster University, the University of Sydney, the University of Johannesburg and the Hospital for Sick Children examined the relationship between teacher distress and student mental health. The researchers analysed data from 23,568 students and 1,478 teachers across 268 schools in Ontario, Canada. The researchers suggested that supporting teachers’ mental health and creating safer school environments could also benefit students’ well-being.

A 2019 study published in the Journal of Affective Disorders by researchers led by Stephen Harding also suggested that better teacher well-being was associated with better student well-being, highlighting the potential importance of supporting teachers’ mental health within schools.

Teachers Day 2026

Teachers’ Day 2026 in India is celebrated on September 5 to honour the contribution of teachers and educators. The day marks the birth anniversary of Dr. Sarvepalli Radhakrishnan, India’s first Vice President and second President, who was a distinguished philosopher, scholar and teacher. Since 1962, his birthday has been observed as Teachers’ Day in India. The occasion recognises teachers’ role in shaping students’ knowledge, character, confidence and well-being, while inspiring future generations to learn, grow and contribute to society.

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5 Important Differences Between Living And Deceased Organ Donation

Updated Sep 5, 2026 | 09:00 AM IST

SummaryDeceased organ donation can help bridge India’s severe organ shortage, while live donation offers another vital transplant pathway, each with distinct processes, possibilities, and limitations.
Organ Donation

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Deceased organ donation covers our organ needs. In India, we are woefully short of organs such as kidneys and livers in cases of liver and kidney failure that need to be transplanted.

Deceased donation, as the name sounds, is a donation by people who are brain dead, whose family has now accepted and has willingly donated their organs for the benefit of the rest of the world.

Live donation, on the other hand, is a donation by living or emotionally related individuals who want to donate a kidney to a diseased patient. A live donation is usually transplanted immediately. It's done in the same centre, and both are done together, as the harvesting of the organ from the donor and transplantation are done simultaneously.

On the other hand, a deceased organ from a cadaveric donor may be harvested in a different geographical location and may be transported over time and over a lot of distance to another centre.

Deceased donation can be done for organs that cannot be transplanted by live donation, which are so consequential to a human body, such as the heart, lungs, and pancreas. They are very vital and cannot be transplanted from a live patient to another.

In a deceased organ donation, we can even donate tissues such as the cornea, skin, and blood vessels, which are required as a part of donation, as a part of other organ donation transplant programmes or, for example, in giving vision to people who have a white cornea or corneal opacity.

These are a few differences between live and deceased or cadaveric donation.

Dr. Vikram Shah Batra, Director - Urology, Kidney Transplant and Uro Oncology, Max Super Speciality Hospital, Dwarka

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