What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Updated Dec 3, 2024 | 06:13 PM IST

SummaryDid you know type 3 diabetes, linked to insulin resistance in the brain, is associated with Alzheimer’s disease? It highlights how metabolic disorders can affect memory, cognition, and brain health.
What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

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World Allergy Day: Hidden Allergy Triggers At Home You May Be Overlooking

Updated Jul 8, 2026 | 05:00 PM IST

SummaryThe experts cautioned that chronic allergies should not be dismissed as a minor inconvenience, as they can affect sleep, respiratory health, and overall quality of life. They recommended consulting a healthcare professional if allergy symptoms persist for several weeks or throughout the year.
World Allergy Day: Hidden Allergy Triggers at Home You May Be Overlooking

Credit: iStock

While many people blame pollen or changing weather for their allergies, health experts say hidden allergens inside the home may be just as responsible. On the occasion of World Allergy Day on July 8, doctors highlighted that dust mites, mold, pet proteins, and household products are among the often-overlooked triggers that can affect indoor air quality and contribute to persistent allergy symptoms.

They also cautioned that chronic allergies should not be dismissed as a minor inconvenience, as they can affect sleep, respiratory health, and overall quality of life.

What Is A Chronic Allergy?

Dr. Sanjiv Dang, ENT & Allergy Specialist, Apollo Hospitals, Delhi, told HealthandMe that allergy symptoms lasting for weeks, months, or throughout the year may indicate chronic allergies and should not be ignored.

He explained that "allergies occur when the immune system overreacts to substances such as dust mites, pollen, mold, pet dander, or certain foods, releasing histamine". This can lead to symptoms including sneezing, nasal congestion, a runny nose, itchy eyes, and throat irritation.

Hidden Allergens Go Beyond Pollen

Also read: UK Met Office Warns of 'Pollen Bomb': What Hay Fever Patients Need to Know

Prof. (Dr.) Dwaipayan Mukherjee, Consultant ENT Surgeon, Kolkata, told HealthandMe that flower pollen is often blamed for seasonal allergies, but it is usually not the main culprit because its grains are larger and less likely to remain airborne. Instead, he said most seasonal allergies are caused by microscopic airborne pollen from grasses, weeds, and trees.

Dr. Mukherjee, also the Past President of the Association of Otolaryngologists of India (AOI), added that homes can also harbor numerous microscopic allergens that negatively affect indoor air quality. Common triggers include:

  • Dust Mites
These microscopic organisms thrive in mattresses, bedding, carpets, curtains, and upholstered furniture, and their presence depends more on warmth, humidity, and skin flakes than on how clean a home appears.

  • Mold
Found in damp areas such as bathrooms, kitchens, basements, and laundry rooms, it releases airborne spores that can cause sneezing, nasal congestion, coughing, and eye irritation. Poor ventilation and excess moisture can make the problem worse.

  • Pet Proteins
Pet allergies are also frequently misunderstood. Dr. Mukherjee explained that pet fur is rarely the main cause of allergic reactions. Instead, proteins found in an animal's skin cells, saliva, and urine trigger symptoms and can remain suspended in the air or settle on furniture, clothing, and bedding.

    Household Products and Indoor Plants

Cleaning sprays, air fresheners, scented candles, and similar products may emit compounds that irritate sensitive airways and worsen allergy symptoms despite creating the impression of a cleaner environment.

Indoor plants can also become a source of allergens if mold develops in damp potting soil or if certain plants release pollen. Outdoor pollen from trees, grasses, and weeds can also enter homes on clothing, shoes, and hair before settling on indoor surfaces, the experts said.

How Persistent Allergies Affect Health

Read More: New HIV Vaccine Produces Powerful Virus-Fighting Antibodies; Human Trials Begin

Dr. Dang said chronic allergies are more than just a runny nose. Persistent nasal congestion can disrupt sleep, leading to snoring, frequent awakenings, daytime fatigue, poor concentration, reduced productivity, and mood changes.

He added that ongoing allergic inflammation can affect both the upper and lower airways. People with chronic allergies are at a higher risk of developing asthma, while those who already have asthma may experience worsening symptoms such as coughing, wheezing, chest tightness, and shortness of breath.

Chronic allergies can also block normal sinus drainage, increasing the risk of recurrent sinus infections. Facial pressure, headaches, post-nasal drip, persistent congestion, and a reduced sense of smell may all indicate allergy-related sinus problems.

How To Prevent Chronic Allergies

The experts advised relying solely on over-the-counter medications, saying they may provide temporary relief without addressing the underlying cause. They noted that prolonged use of certain nasal decongestant sprays can even worsen congestion over time, and also recommended consulting a healthcare professional if allergy symptoms persist for several weeks or throughout the year.

To help manage chronic allergies, the experts recommended:

  • Improving ventilation indoors.
  • Controlling indoor humidity.
  • Using HEPA air cleaners.
  • Cleaning the home regularly.
  • Eliminate excess moisture.
  • Identifying and reducing exposure to allergy triggers.
  • Controlling mold growth indoors.

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Challenge Your Brain To Keep It Young: New Study Says Learning Another Language Can Help

Updated Jul 8, 2026 | 11:47 AM IST

SummaryA new study says learning new languages requires attention, memory, problem-solving and cognitive control, all of which help in keeping the brain younger.
Learning Another Language May Help Slow Brain Ageing

Credit: AI

Learning a second or even a third language may do more than expand your communication skills. According to a new study presented at the Federation of European Neuroscience Societies (FENS) Forum 2026 in Barcelona, learning a new language could also help keep your brain younger as you age.

The findings of the study say that people who speak multiple languages have brains that appear biologically younger than those who speak only one language. The research added to the growing evidence that multilingualism has a beneficial effect on healthy cognitive ageing.

About The Study

To investigate how language affects the ageing brain, researchers analysed brain activity in adults living in Spain's multilingual Basque region.

They used magnetoencephalography (MEG), a non-invasive brain imaging technique that records the brain's electrical activity, along with artificial intelligence (AI) to ascertain each participant's brain age.

Rather than relying on a person's actual age, the AI model assessed how well different regions of the brain communicated with one another, a key marker that normally weakens with age.

Researchers first trained the AI using brain scans from 728 adults with varying language abilities before validating the findings in an independent group of 144 participants.

Read more: Normal Ageing or Alzheimer's? Doctors Explain Six Key Differences to Watch For

The results revealed an association between multilingualism and a younger-looking brain. Compared with people who spoke only one language, bilingual participants had brains that appeared around six years younger. Those who spoke three languages had brains that looked approximately seven years younger, while participants fluent in four languages had brains that appeared up to 13 years younger.

Researcher Lucia Amoruso, deputy scientific director at the Basque Center on Cognition, Brain and Language in San Sebastián, Spain, said, “In simple terms, people who spoke more languages tended to have brains that looked younger than expected for their chronological age.”

The researchers also found that language proficiency mattered. People who learned additional languages earlier in life and became more fluent showed even greater differences in brain age.

Is Multilingualism The Key To Keep Your Brain Younger?

Scientists believe speaking multiple languages provides the brain with a constant mental workout. Regularly switching between languages requires attention, memory, problem-solving and cognitive control, all of which strengthen the neural networks involved in thinking and decision-making.

This exercise may help maintain stronger communication between brain regions, increasing the brain's resilience against age-related decline.

While the team considered factors like age, sex, and education, multilingual individuals may also be more likely to engage in other habits that are beneficial for the brain.

Although the findings are encouraging, the researchers say that the study does not prove that learning another language directly slows brain ageing or prevents dementia. Experts say further long-term studies are needed to determine whether multilingualism can reduce the risk of neurodegenerative diseases such as Alzheimer's disease.

Despite the need for more research, scientists say the findings offer another compelling reason to learn a new language. Whether through formal classes, language-learning apps or everyday conversations, developing language skills could provide meaningful mental stimulation throughout life.

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The New Chapter After Cancer: Focusing On Wellness And Quality Of Life

Updated Jul 8, 2026 | 10:00 AM IST

SummaryThe goal is no longer to eliminate cancer cells, but to create a life that feels fulfilling and meaningful. Survivors are encouraged to focus on three things treatment itself cannot provide: strength, joy, and a renewed sense of control.
The New Chapter After Cancer: Focusing On Wellness And Quality Of Life

Credit: iStock

Completing cancer treatment is often imagined as the moment life returns to normal. The final chemotherapy session ends, follow-up scans show encouraging results, and the long-awaited words, “You’re in remission,” bring immense relief. Family and friends celebrate the milestone, expecting life to pick up where it left off.

Yet for many survivors, the end of treatment marks the beginning of a different journey. The hospital visits may become less frequent, but new questions often take their place. Will energy levels ever return? Is it normal to still feel anxious before every check-up? How does one rebuild a life that has been profoundly changed by illness?

Life After Cancer

Life after cancer is not simply about surviving; it is about learning to live well again. This phase is an opportunity to focus not only on physical recovery but also on emotional healing, meaningful relationships, and rediscovering a sense of purpose. Survivorship is not defined by the absence of disease alone; it is measured by the quality of life that follows.

During treatment, every decision revolves around cancer. Appointments, medications, scans, and side effects dominate daily life. Once treatment ends, the focus gradually shifts from fighting the disease to rebuilding health and well-being. This transition, often referred to as survivorship care, is about moving from crisis management to long-term wellness.

The goal is no longer simply to eliminate cancer cells, but to create a life that feels fulfilling and meaningful. Survivors are encouraged to focus on three things treatment itself cannot provide: strength, joy, and a renewed sense of control.

Quality of life after cancer extends far beyond follow-up scans and medical reports. It encompasses physical, emotional, social, and practical well-being. Paying attention to each of these areas can help survivors thrive rather than merely cope.

Physical Recovery After Cancer Treatment

Physically, the body often needs time to recover from the effects of chemotherapy, surgery, radiation, or hormone therapy. Fatigue, reduced stamina, neuropathy, weight changes, and muscle loss are common challenges. Regular movement plays a critical role in recovery.

Experts recommend at least 150 minutes of moderate exercise each week, along with two sessions of strength training to rebuild muscle and improve energy levels. For survivors experiencing lymphedema, pelvic floor concerns, or mobility limitations, working with a physiotherapist can provide targeted support. A balanced diet rich in protein also helps restore strength and independence.

Emotional Recovery Post Cancer Treatment

Emotional recovery deserves equal attention. Fear of recurrence, anxiety before follow-up scans, survivor's guilt, and grief for the life that existed before diagnosis are all common experiences.

These feelings are not symptoms of weakness; they are natural responses to a life-changing event. Seeking support from a psycho-oncologist, counsellor, or support group can significantly improve emotional well-being. Even simple practices such as mindfulness, journaling, or spending a few quiet minutes each day focusing on the present moment can help reduce stress and build resilience.

Cancer's Impact On Relationships And Financial Pressures

Cancer can also reshape relationships. Some friendships may change, while family members and partners may continue adjusting to roles they adopted during treatment.

Open conversations about needs, limitations, and expectations can help strengthen these relationships. Reconnecting with supportive people, participating in survivor communities, or mentoring newly diagnosed patients can create a sense of belonging and purpose. Healing is often easier when it happens in the company of others.

Practical concerns can persist long after treatment ends. Financial pressures, career interruptions, insurance challenges, and concerns about returning to work can affect overall well-being. Seeking guidance from social workers, financial counsellors, or patient support organizations can help survivors navigate these issues. In India, government initiatives such as Ayushman Bharat, state-level healthcare schemes, and various non-governmental organizations may offer valuable assistance.

Challenges Of Survivors

One of the greatest challenges survivors face is the expectation of returning to the person they were before cancer. However, recovery is not about going back; it is about moving forward. A new normal often emerges, the one shaped by deeper self-awareness, healthier boundaries, and a greater appreciation for everyday moments.

Many long-term survivors describe experiencing what experts call post-traumatic growth. They report stronger relationships, clearer priorities, and a renewed sense of purpose. They become more intentional about how they spend their time and energy, recognizing that health and meaningful experiences deserve as much attention as professional achievements.

The first year after treatment is a time of adjustment. Establishing healthy routines, gradually resuming work and hobbies, staying consistent with follow-up appointments, and setting goals unrelated to cancer can help restore confidence. Whether it is taking a short trip, learning a new skill, planting a garden, or simply enjoying time with loved ones, these experiences remind survivors that life extends beyond medical milestones.

Risk of New Symptoms

At the same time, wellness does not mean ignoring new symptoms. Persistent pain, unexplained weight loss, unusual bleeding, ongoing fatigue, or symptoms of anxiety and depression that last more than two weeks should be discussed with a healthcare provider. Survivorship care is an essential part of recovery, and seeking help when needed is a sign of self-care, not concern.

Cancer may have changed the course of life, but it does not define its future. The chapter after treatment may look different from the one that came before, but it can still be rich with meaning, connection, and hope.

The treatment phase was about fighting to survive. The next phase is about discovering what makes life meaningful again. It is about protecting quality of life with the same determination that carried survivors through treatment—because surviving cancer is not only about living longer, but about living well.

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