Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

Beyond being a medical challenge, multiple sclerosis (MS), which affects nearly three times as many women as men, raises emotional and physical concerns among women.

MS is a neurological condition that affects cognitive, emotional, motor, sensory, or visual functions. It is also a chronic autoimmune disease that is caused when a person’s immune system attacks their brain and spinal cord.

According to the UK-based MS International Federation, an estimated 2.8 million people live with MS worldwide, with prevalence increasing globally. However, women make up about 75 percent of MS patients globally.

However, women are disproportionately affected. The diagnosis gets more emotionally challenging for women as it often appears during early adulthood -- a key period for women building their careers, relationships, and families.

Estrogen, genetics and a lack of Vitamin D are major reasons for its increased prevalence in women.

Beyond the clinical symptoms, the anxiety, depression, mood changes, and stress, driven by uncertainty about disease progression, impact the daily life of women. Concerns about pregnancy, parenting, work, and long-term independence can further intensify the emotional burden.

“MS is significantly more prevalent in women, often striking during their most pivotal years. For many women, the diagnosis goes beyond a medical challenge; it becomes a profound emotional crossroads centered around family planning. They face daunting questions: Can I safely carry a pregnancy? Is breastfeeding possible? Will I have the physical stamina to care for a child? These are not merely clinical concerns; they are deeply personal anxieties about identity, motherhood, and the future,” Dr. Sudhir Kumar, Sr. Consultant Neurologist, Apollo Hospital, Jubilee Hills, Hyderabad, told HealthandMe.

“Multiple sclerosis is increasingly recognized as a disproportionate neurological burden among women. Globally, women are affected nearly two to three times more often than men, a pattern believed to arise from a complex interaction of immune system behavior, hormonal influences such as estrogen fluctuations, genetic susceptibility, and environmental triggers, including low Vitamin D levels and viral exposures,” added Dr. Manish Gupta, Director – Neurology, Max Super Specialty Hospital, Noida.

Symptoms of multiple sclerosis can be different from person to person. They can come and go or get worse over time. MS can affect any part of the central nervous system.

MS symptoms can worsen with heat or during other infections, such as urinary tract or respiratory infections.

Common symptoms can include:

• vision problems
• difficulty walking or keeping balance
• difficulty thinking clearly
• numbness or weakness, especially in the arms and legs
• muscle stiffness
• depression
• problems with sexual function or urination
• feeling very tired.

“No two patients experience MS in the same way. Symptoms depend on the location of demyelinating lesions in the brain or spinal cord, affecting vision, mobility, cognition, balance, or sensation. This biological variability makes early diagnosis and timely, high-efficacy intervention critical. The goal today is no longer just to manage relapses. It is to limit ongoing subclinical inflammation, prevent silent progression, and delay long-term disability,” Dr. Kumar said.

Why Treating Multiple Sclerosis Is Difficult

MS is an inflammatory condition that results from an autoimmune attack on myelin -- the fatty insulation that surrounds the nerves in the brain and spinal cord.

This disrupts the electrical impulses that are sent through the nerves to the rest of the body and results in scars (plaques or sclerosis).

“Multiple Sclerosis is one of the most complex neurological disorders we encounter in clinical practice, not because it is untreatable, but because it is unpredictable. MS is an immune-mediated disease characterized by inflammation and demyelination — damage to the protective myelin sheath that insulates nerve fibers in the brain and spinal cord. When this insulation is stripped away, nerve signals slow down or become distorted, producing a wide spectrum of symptoms, varying from fatigue, blurred vision, and dizziness to limb weakness, imbalance, or sensory disturbances,” Dr. Subhash Kaul, Consultant Neurologist at KIMS Hospital, Hyderabad, told HealthandMe.

Many of these are invisible, fluctuating, and easily dismissed, both by patients and sometimes even by primary care providers. It is not uncommon for individuals in the early stages of MS to be misdiagnosed.

“This delay in recognising the disease is deeply concerning, because MS strikes people in the prime of their lives — when they are building careers, raising families, and contributing economically. If left untreated, the disease does not remain static; inflammation accumulates silently, relapses leave residual deficits, and disability compounds over time. This is precisely why early and appropriate treatment matters,” said Dr. Kaul.

Yet, experts stated that early diagnosis remains crucial. Regular neurological evaluation for persistent numbness, vision disturbance, or unexplained fatigue allows timely therapy. Disease-modifying treatments, adequate sunlight exposure, physical activity, and stress management help slow progression and preserve long-term neurological function.

“Multiple Sclerosis is not a series of unfortunate episodes; it is a silent, relentless fire. From the moment of onset, MS acts as a chronic, immune-mediated assault on the central nervous system, often causing irreversible damage long before the first visible symptom appears. As one of the leading causes of non-traumatic disability in young adults, we must confront a sobering reality: even when a patient appears clinically stable, “smoldering” inflammation frequently continues beneath the surface, gradually eroding brain volume and neural pathways,” Dr. Kumar said.

“By intervening decisively at the outset, we can suppress smoldering inflammation, preserve long-term neurological function, and give women the confidence to pursue the lives and families they envision,” he added.

Chief Minister Siddaramaiah’s announcement during his presentation of the Karnataka State Budget 2026-27, proposing a ban on social media for children under 16 years of age, has sparked intense interest among parents and professionals alike. As the first state in India to attempt such a sweeping measure, the government has invited us to reflect upon this proposal.

We are in an age where technological advancements have blurred the lines between online and offline worlds, blending them seamlessly. While this is the norm in the world of adults, it has silently reshaped childhood with increased screentime.

Concerns about digital dependency, anxiety disorders in children, and reduced focus in academic and non-academic tasks have already made it to research papers and therapy rooms.

But Karnataka has now shifted the focus from debate to discussion and action. While a ban may reduce certain risks of social media exposure, children’s psychological needs like social connection, belonging, peer group and individual identity, besides guidance, must be nurtured if such protections are to be meaningful.

The Pediatric Perspective: A Medical Minefield

From a psychological perspective, the idea of an age-based social media ban is both promising and complex. On the brighter side, reducing screen usage can help address problems of poor sleep schedules, heightened anxiety, and trouble concentrating in studies or tasks. These problems have become increasingly common among not only adolescents, but very young children too.

However, age alone cannot be used as the single measure of readiness to implement this proposal. Two children of the same age may differ vastly in maturity levels, coping skills, and the ability to use technology responsibly.

The deeper issue is not simply “how much time” children spend online, but “what they do there”. Creative exploration, learning, and connection can be enriching, while endless scrolling reinforces dependency and stress.

A ban can reduce such harmful patterns, but in order to have real impact, such a move should be paired with support for children’s psychological needs to help them combat loneliness, handle peer pressure, and guiding their search for identity. Addressing these issues along with the ban can make the protection well intended, more meaningful and long-lasting.

The Silent Crisis: Nocturnal Anxiety And Doom-scrolling

Late-night scrolling (doom scrolling) is more than just a disruption of sleep. It is a psychological trigger for worry and overthinking. In the quiet of the night, children are left alone with a flood of unfiltered information, which can heighten anxiety, and unwanted exposure to inappropriate content.

An effective way to combat the dangers of unsupervised social media access could be “digital sundowning” i.e. setting clear screen time guidelines for children. Families can create screen-free zones, especially in bedrooms, bathrooms, and at dining tables, or create “phone parking zones” – a specific place in the house to keep all phones so no one is carrying them around all the time. This can encourage children towards healthier routines.

Unlike government-imposed bans, household practices can set healthy and firm boundaries, reinforce self-regulation and reduce the anxiety that comes from constant connectivity and information overload.

Symptoms In The Clinic: Beyond The Screen

In therapy rooms and schools, counsellors are addressing more and more concerns about children and adolescents spending excessive time with their screens. Some of the common ones are highlighted here:

• Social Isolation in Hyper Connectivity: Children may appear socially active online but withdraw from face-to-face interactions, leaving them paradoxically isolated.

• Body Image Concerns: Exposure to curated images on social media can fuel anxiety about appearance among growing children, who are already socially awkward during adolescence. This goes beyond normal teenage insecurity and can spiral into unhealthy self-image or self-criticism.

• Academic Fatigue: Digital content trains the brain to expect constant novelty and quick changes within a short time span of seconds or minutes, which makes textbooks and traditional classroom driven problem-solving feel slow and tiring. This leads to academic fatigue, where children struggle to sustain focus for deeper learning.

• Fear of Missing Out (FOMO): Constant checking of devices reflects a deep-seated need for validation and belonging. FOMO keeps children’s nervous systems on a constant loop of high alert, thus undermining emotional stability.

What Comes Next: The Prioritization Framework

For this ban to have a lasting impact, it needs to draw on psychological principles. Restrictions work best when paired with meaningful alternatives, as children are known to engage positively when they feel supported rather than restricted or scolded. A framework needs to be set up where learning and guidance is prioritized and alternatives offered are strengthened. Some pointers:

Digital Literacy in Schools: Children should be taught not only to limit screen time but also to understand how online platforms work. Lessons on algorithms, advertising, and curated content help them understand and evaluate what they see, so they become more resilient to digital influence.

Parental Guidance Programs: As with other trained behaviors, parents play a central role in shaping healthy digital habits too. Guidance programs can provide resources and strategies for families to showcase balanced device use. When adults demonstrate mindful online usage and behavior, children are likely to follow.

Physical and Social Alternatives: If digital spaces are restricted, offline opportunities must be strengthened. Sports, arts, and community activities help children gain a sense of belonging and enjoyment beyond screens, thus building confidence and social skills in real life.

Collaboration with Tech Companies: Lasting change requires cooperation of technology providers and social media platforms. Stricter age verification systems and design changes at the source are needed, rather than placing usage responsibility on children. By remodeling platforms, risk of unsupervised penetration of digital content can be mitigated so children may still be allowed safe, and age appropriate engagement on social media.

As Karnataka moves into this new territory, one thing is certain – the intention is noble. However, the execution of such a ban will require a fine balance of protection and empowerment, as it attempts to re-imagine childhood experiences in an age where the “virtual” and the “real” are meshed together. Whether this becomes a guiding model for the rest of the country, will depend entirely on how thoughtfully it is carried out.

Karnataka’s proposed ban is a bold first step, but its true impact will depend on how parents, teachers, and policymakers align on this, because healthy childhoods thrive not on restrictions, but through resilience, support, guidance, and strong offline connections that nurture growth and belonging.

Iron deficiency is one of the most common nutritional problems among women, but in the juggle between professional and household responsibilities, a majority of women tend to ignore their health. However, the detecting the mild symptoms in the beginning can help boost treatment and improve quality of life for women, said experts, while stressing the need for timely screening, ahead of International Women's Day.

International Women's Day is observed globally on March 8 every year.

According to health experts, in a month, around 5 out of 10 women between the ages of 30 and 45 visit doctors with complaints such as persistent weakness, headaches, and tiredness. These symptoms are often linked to iron deficiency and put women at risk of developing anemia.

“Iron deficiency is a matter of concern among women, because the symptoms, such as fatigue and weakness, are neglected until the condition becomes serious,” said Dr. Upasana Garg, Regional Technical Chief, Apollo Diagnostic Mumbai.

Dr. Garg said iron deficiency can be detected through simple blood tests that will be advised by the expert and will play a pivotal role in early diagnosis and timely treatment.

These include tests for

• Hemoglobin levels -- are carried out to measure the amount of oxygen-carrying protein in the blood and indicate if a woman has anemia

• Serum ferritin and iron levels -- to gauge the amount of stored iron in the body and help detect iron deficiency even before anemia develops

• A complete blood count (CBC) -- to measure red blood cells, including their size and number, which checks if the body is producing healthy blood cells.

Anemia In Women

Anemia is a major public health concern, mainly affecting young children, pregnant and postpartum women, and menstruating adolescent girls and women.

The World Health Organization (WHO) estimates that 40 percent of all children aged 6–59 months, 37 percent of pregnant women, and 30 percent of women 15–49 years of age worldwide are affected by anemia.

Anemia occurs when there isn’t enough hemoglobin in the body to carry oxygen to the organs and tissues.

In severe cases, anemia can cause poor cognitive and motor development in children. It can also cause problems for pregnant women and their babies. It is often caused by a lack of iron in the blood.

“Iron is a necessary mineral which helps the body to produce hemoglobin, a protein in red blood cells that carries oxygen to different parts of the body. When the body does not have enough iron, it is unable to produce healthy red blood cells. This condition is known as iron deficiency or iron deficiency anemia,” said Dr. Ritu Agrawal, Gynecologist, Zynova Shalby Hospital, Mumbai.

Dr. Agrawal said that women are more likely to experience iron deficiency when compared to men.

The major reason is blood loss during menstruation, and women who have heavy periods are at a higher risk.

During pregnancy, when the body needs extra iron to support the growing baby, the risk of anemia increases in the mother.

Other factors include poor diet, skipping meals, and not eating enough iron-rich foods.

Early Screening And Treatment

The common symptoms of anemia in women include:

constant tiredness,

weakness,

pale skin,

shortness of breath,

dizziness,

headaches,

hair fall

difficulty concentrating

frequent infections due to reduced immunity

Dr. Agrawal said that 50 percent of women tend to ignore early symptoms of anemia.

“In a month, around 5 out of 10 women between the ages of 30–45 visit with complaints such as persistent weakness, headaches, and tiredness, which are often linked to iron deficiency and put them at risk of developing anemia. If iron deficiency is not treated in time, it can lead to several health complications,” she added.

Severe anemia can also lead to heart-related problems, such as irregular heartbeat or shortness of breath.

The experts noted that detecting iron deficiency on time and initiating immediate treatment is necessary for women's better health.

Management of iron deficiency includes

• improving diet and taking iron supplements as advised by any expert
• Have iron-rich foods like spinach, beans, lentils, nuts, and dates
• Vitamin C–rich foods, such as oranges and lemons.