Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

With advancements in medical technology, hip replacement surgery has evolved significantly over the years. One of the most promising innovations in this field is the Direct Anterior Approach (DAA) Total Hip Replacement, a modern technique that offers patients a safer procedure, reduced pain, and faster recovery.

Unlike traditional hip replacement surgeries, the DAA technique allows surgeons to access the hip joint from the front through a small incision. The biggest advantage of this approach is that muscles are not cut during the surgery. Instead, they are gently separated, which helps minimize tissue damage and reduces post-operative pain considerably.

This muscle-sparing approach has transformed patient recovery experiences. Most patients are able to stand and walk on the same day of surgery, and hospital stays are generally shorter. Recovery is smoother, allowing individuals to return to their normal routine within three to four weeks in most cases.

The DAA technique is especially beneficial for patients suffering from chronic hip pain, restricted movement, or severe joint damage. Common conditions that may require hip replacement include osteoarthritis, avascular necrosis (AVN), rheumatoid arthritis, old hip fractures, and long-standing degenerative joint conditions. When medications, physiotherapy, and injections fail to provide lasting relief, hip replacement surgery can significantly improve mobility and quality of life.

Compared to conventional hip replacement procedures, DAA offers several advantages. The surgery involves a smaller incision, less blood loss, minimal muscle damage, and lower post-surgical discomfort. Patients are able to regain movement faster and often experience greater confidence during rehabilitation.

One of the most common concerns among patients is the fear of severe pain after surgery. However, with modern pain management techniques and advanced surgical methods, discomfort after DAA hip replacement is usually minimal and manageable. Patients today recover much more comfortably than they did in the past.

Another important factor is the durability of modern implants. Advances in implant technology have significantly improved their lifespan, with many implants lasting more than 25 years. Maintaining a healthy body weight, staying physically active, and following medical advice can further improve the longevity and effectiveness of the implant.

After successful recovery, patients are generally able to resume a normal and active lifestyle. They can return to work, perform household activities independently, and participate in light exercises such as yoga, swimming, and stationary cycling. The primary goal of hip replacement surgery is not just pain relief, but restoring confidence, mobility, and independence.

Preparation before surgery also plays an important role in achieving better outcomes. Patients are advised to maintain controlled blood sugar levels, blood pressure, and overall heart health. Informing doctors about ongoing medications, performing basic physiotherapy exercises before surgery, and preparing a comfortable recovery environment at home can contribute to a smoother rehabilitation process.

Hip pain should never be ignored, especially when it begins affecting daily life and mobility. Timely treatment and the right surgical approach can make a remarkable difference. The Direct Anterior Approach has made hip replacement surgery simpler, safer, and more patient-friendly, helping individuals return to an active and pain-free life much faster than before.

Dr. Ishwar Bohra is Senior Director and Senior Joint Replacement Surgeon at BLK-Max Super Speciality Hospital, New Delhi.

Climate change is increasingly emerging as a major public health threat, contributing to a growing burden of disease worldwide and creating favorable conditions for the spread of infectious illnesses, according to health experts on World Environment Day 2026.

World Environment Day is observed every year on June 5 to raise awareness about the need for immediate action as heatwaves intensify, air pollution worsens, ecosystems degrade, and climate anxiety grows worldwide, even as the world crosses the UN-mandated 1.5°C limit.

The theme for World Environment Day 2026 is "Inspired by Nature. For Climate. For Our Future". It focuses on climate change and the signals nature is sending such as rising seas, raging wildfires, heatwaves and melting glaciers.

To understand the intersection between climate change and health impacts, HealthandMe spoke to two experts.

Heatwaves, Pollution And Food Insecurity

According to Dr. Sabine Kapasi, UN advisor, the consequences are no longer limited to environmental damage. Rising temperatures, worsening air pollution and shifting weather patterns are already affecting human health across the globe.

“Longer and more intense heatwaves are resulting in more cases of heat-related illness. Air pollution continues to exacerbate respiratory diseases, while changing weather patterns are impacting food security and nutrition in many parts of the world,” she said.

Importantly, in India, children, pregnant women and communities living in flood- and drought-prone regions face some of the greatest risks. Women are often disproportionately affected due to challenges related to water supply and sanitation. While India has reduced malaria cases by nearly 80 per cent since 2015, climate change is creating new health challenges that health systems will need to address in the coming years.

Infectious Disease Outbreaks

Also read: Dengue Is Spreading Beyond Monsoons And Into New Regions Across India, Says Expert

The expert warned that changing climatic conditions are also increasing the risk of infectious disease outbreaks. Dr. Kapasi told HealthandMe that rising temperatures and altered rainfall patterns are allowing mosquitoes to breed more easily and remain active for longer periods.

Floods further compound the problem by contaminating drinking water, damaging sanitation systems and disrupting healthcare services. Displacement caused by disasters can force families into crowded living conditions, increasing the risk of infections such as cholera, leptospirosis and tuberculosis.

“Recent climate-related disasters in South Asia and Africa have shown how quickly an environmental crisis can turn into a public health challenge,” she noted.

The spread of mosquito-borne diseases such as dengue, malaria and chikungunya is also becoming a growing concern. Health authorities around the world are reporting these diseases in areas where they were previously uncommon.

Globally, countries including Italy, France and Spain have also witnessed an increase in locally transmitted dengue and chikungunya cases over the past decade. In the United States, locally acquired malaria cases were recently reported in Florida and Texas, marking the first such transmission in nearly 20 years.

India is also experiencing rising dengue activity. Dengue outbreaks have become a regular occurrence during the monsoon and post-monsoon seasons in many states. Estimates suggest dengue cases could reach around 278,000 in 2025, up from roughly 230,000 the previous year. Experts say warmer temperatures and changing rainfall patterns are helping disease-carrying mosquitoes survive and spread more effectively.

Climate Change And Shifting Disease Patterns

Also read: Forget Supplements: Barbara O'Neill Says Sleep Is The Best Medicine

Dr. Devarsetty Praveen, Program Director at NIHR GHRC for Non-communicable Diseases and Environmental Change, hosted by The George Institute India, in partnership with Imperial College London, said climate change is affecting both communicable and non-communicable diseases.

“Climate change is increasing health risks through rising temperatures, extreme weather events, worsening air quality and changing disease patterns. In India, it is affecting both communicable and non-communicable diseases, with vulnerable populations bearing the greatest burden,” he told HealthandMe.

He noted that research has found that people living with chronic conditions such as hypertension and diabetes are particularly vulnerable to extreme heat, underscoring the growing link between climate change and non-communicable diseases.

Dr. Praveen added that climate change influences disease transmission by altering temperature, humidity and rainfall patterns while also affecting water quality, food systems and interactions between humans, animals and disease vectors.

“These changes can make outbreaks more frequent, more widespread and harder to predict,” he said.

How To Reduce Climate-related Health Risks

To reduce climate-related health risks, the experts recommend staying informed about weather conditions, remaining hydrated, limiting outdoor exposure during extreme heat and taking precautions against mosquito bites.

People with chronic conditions such as hypertension, diabetes, heart disease and kidney disease are advised to maintain adequate medication supplies and consult healthcare providers during periods of extreme heat.

According to the experts, awareness and early action remain critical to protecting public health as climate change continues to reshape disease patterns around the world.

To reduce the risk of mosquito-borne diseases, people should make sure that water does not get collected in buckets, coolers, flower pots or other containers around the home. Additional precautions include the use of mosquito repellents, sleeping under nets when necessary and wearing clothing that covers the arms and legs.

Dr Sabine said food and water safety is particularly important after heavy rain or flooding. Proper food storage, clean drinking water and good hygiene practices can go a long way in preventing many infections. Those with pre-existing medical conditions should also have essential medicines within easy reach during extreme weather.

The United States has been working on reducing smog for more than a decade and has become quite successful in this endeavor, but since 2015, the situation has changed for the worse as a new study reveals that the smog level is once again on the rise, and the main reason behind this is another long-term problem of the nation, wildfire.

The federal regulations tightened on power plants, cars, and diesel engines, which in turn caused a drop in the national smog level by 11% from 2003 to 2015. Since then, cases of wildfire have increased, resulting in the smog level going up by 4%. The study finds that if the current trend continues, it will cause smog to go back up to 2003 levels in 20 years.

The study in the journal Science has also calculated a surge in deaths from ozone attacking lungs by comparing death rates in clean and dirty air. They estimated a surge of 318 American deaths per year since 2013 due to smog.

The co-author of the study, Meng Zhou, a University of Iowa wildfire researcher, said, “For the last 20 years, by regulations, we keep decreasing the emissions." He added, “However, because of wildfires, which are actually from natural hazards, all those kinds of effort were wiped out.”

The study also flagged concerns about the current smog situation and its possible impact on the population. University of Washington public health and climate scientist Kristie Ebi said, “Higher daily ozone concentrations can increase asthma attacks, hospital admissions, and mortality.” She added, “still a very important pollutant, which is why it's regulated.”

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The research finds that the heavy wildfire smoke seasons of 2022, 2023, and 2024, mainly in Canada, created a massive amount of smog, and this then came down south. As a result, about 43 million people got exposed to smog levels that exceeded the current EPA safety standards. The wildfires in Canada have been particularly severe since 2022.

The problem is also with the massive wildfires in the mainland US, as the National Interagency Fire Center's data also shows that the average amount of land in the US that wildfires burn every year has increased by 9% higher than it was from 2003 to 2014.

Also Read: CDC Warns That Tick Bites Are Surging Across The US: What You Need to Know

What Are The Possible Health Impacts?

There are many short-term and long-term impacts on public health from the constant exposure to air pollution. As per IQAir, in the short term, people experience irritation in the eyes, throat, and nose, along with irregular heartbeats, asthma attacks, coughing, chest tightness, and difficulty breathing.

Prolonged exposure also intensifies these risks and leads to long-term effects such as chronic respiratory illnesses like bronchitis, asthma, and emphysema. Pollutants can also damage lung tissue, increasing the likelihood of lung cancer. Air pollution also leads to an increased risk of heart attacks and strokes, and could also be linked to premature death.