Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

Cosmetic treatments are no longer rare or exclusive. A quick search online reveals hundreds of options promising smoother skin, sharper features, or younger-looking results. Walk through any city, and you’ll find salons and aesthetic studios advertising fillers, lasers, chemical peels, and anti-ageing injections. On the surface, it all looks routine. But for many doctors, this growing trend has also raised an uncomfortable question: who is actually performing these procedures?

The skin is considered a cosmetic surface that can be polished or fixed quickly. In reality, skin is the largest organ of the body and is closely related to other deeper structures like the blood vessels, nerves, and muscles. Procedures that alter or inject into these layers require medical knowledge and technical training.

When carried out by individuals without proper qualifications, even treatments marketed as “simple” can turn risky.

The Rise of Unregulated Aesthetic Treatments

In recent years, cosmetic procedures have moved far beyond hospitals and specialised clinics. Many services are now offered in beauty salons or small aesthetic centres that operate with very little medical know-how.

The treatments themselves may sound harmless: lip fillers, Botox injections, laser resurfacing, or skin tightening.

Unfortunately, the procedures done are not merely surface-level. For example, injectables are not something done without considering the underlying structures and related anatomy. A small error or poor technique can result in uneven, unbalanced results, or prolonged swelling or more serious complications such as blocked blood vessels.

Laser treatments also require expertise. Different skin types react differently to energy-based devices. Incorrect settings can result in burns, pigmentation changes, or scarring that may take months to correct.

Medical Expertise Matters

Qualified dermatologists and plastic surgeons approach cosmetic procedures with a very different mindset. The process rarely begins with the treatment itself. It begins with evaluation.

A trained specialist looks at the patient’s medical history, skin condition, lifestyle habits, and expectations before recommending any intervention. Sometimes the safest recommendation is to delay a procedure or choose a less aggressive approach.

Patients should also take a moment to verify the doctor's qualifications to perform the procedure. A qualified plastic surgeon typically holds an MCh or DNB degree in plastic surgery, whereas a dermatologist holds an MD or DNB in Dermatology. The risks of choosing a provider on the basis of cost or accessibility can expose patients to unnecessary risks.

Medical training also prepares specialists to recognise complications early and manage them effectively. Even well-performed procedures can occasionally cause reactions. The difference lies in how quickly those issues are identified and treated.

There is a Hidden Cost to “Convenient” Treatments

Lower prices and easy accessibility often attract people toward unregulated services. What many do not realise is that fixing a poorly performed cosmetic procedure can be far more complex than the original treatment.

Corrective procedures may involve dissolving fillers, repairing damaged skin, or undergoing additional medical care to restore normal appearance. Apart from the financial cost, these situations can also affect confidence and emotional well-being.

Choosing Safety Over Convenience

Cosmetic procedures can be safe and effective when performed by trained medical professionals. Patients should feel comfortable asking about qualifications, experience, and the type of equipment being used. A responsible practitioner will always prioritise safety, proper consultation, and realistic expectations.

Aesthetic treatments may focus on appearance, but the responsibility behind them is medical. Your skin deserves expertise, careful judgement, and the assurance that every step is taken with your health in mind.

An estimated 4.9 million children died before reaching their fifth birthday in 2024, including 2.3 million newborns, according to the latest United Nations report on global child mortality. The findings were released in the report Levels and Trends in Child Mortality, which examines the leading causes of deaths among children worldwide.

The report notes that many of these deaths could have been prevented through simple and affordable health measures. Access to quality healthcare, timely treatment, vaccination, and better nutrition remain key factors in reducing child deaths.

Over the past two decades, the world has made significant progress. Global under five deaths have dropped by more than half since 2000. However, the pace of improvement has slowed in recent years. Since 2015, the rate of decline in child mortality has fallen by more than 60 percent, raising concerns among health experts.

India Shows Steady Progress In Reducing Child Mortality

Despite global challenges, India has made notable progress in improving child survival rates through sustained public health efforts.

According to the United Nations Inter Agency Group for Child Mortality Estimation (UNIGME) Report 2025, India has steadily reduced deaths among newborns and young children over the past decades. The Union Health Ministry said the country has played an important role in lowering child mortality across South Asia.

India’s Neonatal Mortality Rate, which measures deaths within the first 28 days of life, has seen a major decline. In 1990, the rate stood at 57 deaths per 1,000 live births. By 2024, it had dropped to 17.

A similar trend was seen in the Under Five Mortality Rate. In 1990, India recorded 127 deaths per 1,000 live births among children under five. By 2024, that number had fallen sharply to 27.

Health officials attribute this progress to targeted public health programmes, improved hospital deliveries, and wider vaccination coverage.

Malnutrition And Infections Still Claim Many Young Lives

The report highlights that several preventable health conditions continue to drive child deaths across the world.

For the first time, the report estimated deaths directly caused by severe acute malnutrition. It found that more than 100,000 children aged between one month and five years died due to severe malnutrition in 2024.

Experts believe the real impact may be even higher because malnutrition often weakens the immune system. This makes children more vulnerable to common infections such as pneumonia, diarrhea, and malaria, which can become life threatening.

Some countries reporting high numbers of malnutrition related deaths include Pakistan, Somalia, and Sudan.

Newborn Complications Remain A Major Concern

Nearly half of all deaths among children under five occur during the newborn stage. This reflects slower progress in preventing deaths around the time of birth.

The leading causes of newborn deaths include complications related to premature birth, which account for about 36 percent of cases. Problems during labor and delivery contribute to around 21 percent of deaths.

Other important causes include infections such as neonatal sepsis and certain birth defects.

After the first month of life, infectious diseases remain the main threats to children’s survival. Malaria, diarrhea, and pneumonia are among the biggest causes of death.

Health Experts Stress Need For Continued Investment

The report also points out that global funding for maternal and child health programmes is facing increasing pressure. This could slow progress in reducing child deaths in the coming years.

Experts stress that investing in child health remains one of the most effective public health strategies. Basic interventions such as vaccination, treatment for severe malnutrition, and skilled care during childbirth can save millions of lives.

According to the report, such measures not only improve health outcomes but also strengthen economies by creating healthier and more productive populations.

A lighthearted Instagram reel by Delhi-based influencer Yuvraj Dua has turned into a broader conversation about the health risks of excessive sugar consumption after Prime Minister Narendra Modi responded with a public message urging people to cut down on sweets.

Dua made a humorous request to the Prime Minister about his father’s eating habits, explaining that his father is a devoted follower of PM Modi and tends to take his words very seriously.

He asked if the Prime Minister spoke against sweets during his monthly radio programme “Mann Ki Baat”, it might finally convince his father to control his sugar intake.

“If in the next Mann Ki Baat you say something against sweets, my father’s sugar will come under control,” he said in the video.

The reel quickly gained traction online and eventually caught the Prime Minister’s attention.

Responding to the post on Instagram, PM Modi on his Instagram story used the opportunity to deliver a broader public health message about the dangers of consuming too much sugar.

“On Yuvraj’s request, I urge his father and everyone out there to reduce sugar intake, be healthy and be happy,” he wrote.

The Prime Minister also warned that excessive sugar consumption is linked to several serious health conditions.

“Focus on your wellbeing. Eat well, eat healthy. Excessive sugar invites a range of diseases. Then there is the looming threat of obesity. Also, do make Yoga a part of your lives. It is a great way to remain fit and active,” he added.

India And Diabetes

India today carries one of the heaviest diabetes burden in the world. This is a crisis that is not just driven by genetics, but also by rapid urbanization, sedentary routines, shifting diets, stress, and late diagnosis. With over 101 million Indians currently living with diabetes in India, and 136 million in the pre-diabetic stage, as stated by the latest ICMR estimates, the country is facing an epidemic. This threatens to overwhelm the healthcare system in the coming years.

Diabetes is one of the chronic lifestyle conditions that most older adults fear developing, especially past the age of 40. This is when body's main source of energy or glucose is too high. However, recent cases show that diabetes may no longer be a disease of aging. While most people who are middle-aged or older adults develop Type 2 diabetes, there is in fact a rise in cases among the youth, including children.

In India too, there is a sharp rise in diabetes across all age groups, with many cases going undiagnosed until complications set in, says Dr Mayanka Lodha Seth, chief pathologist at Redcliffe Labs. " Diabetes cases are rising not just among older adults but also in children, teenagers, and youngsters in their 20s & 30s," says the doctor.

When large amounts of sugar are consumed regularly, the body experiences repeated spikes in blood glucose levels. Over time, this can lead to insulin resistance, a condition where the body’s cells stop responding effectively to insulin. This is one of the key mechanisms behind the development of type 2 diabetes.

Excess sugar intake is also strongly linked with weight gain. Sugary foods and beverages are often calorie dense but nutritionally poor, making it easy to consume large amounts of calories without feeling full.

Research has also shown that frequent consumption of sweets and sugary drinks can increase the risk of fatty liver disease and dental problems.

Public health organizations across the world recommend limiting added sugar in daily diets. The World Health Organization suggests that added sugar should make up less than 10 percent of total daily calorie intake, and ideally below 5 percent for additional health benefits.

Following the Prime Minister’s response, Dua reacted with amusement and relief, hoping that the message would finally persuade his father to change his habits.

“Now even Modi ji has said it. Papa, please listen,” he wrote in response.