What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Updated Dec 3, 2024 | 06:13 PM IST

SummaryDid you know type 3 diabetes, linked to insulin resistance in the brain, is associated with Alzheimer’s disease? It highlights how metabolic disorders can affect memory, cognition, and brain health.
What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

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Delhi Sees Some Relief From Toxic Air; GRAP IV Removed, 'Will Bring Down Pollution In 5 Years,' Says Nitin Gadkari

Updated Dec 25, 2025 | 11:20 AM IST

SummaryDelhi saw slight relief as AQI dropped to 221, prompting the lifting of GRAP IV, though smog and fog persist under a yellow alert. Restrictions under GRAP I–III remain. Union Minister Nitin Gadkari highlighted transport emissions as a major cause and outlined initiatives like electric vehicles, alternative fuels, and rice-straw-based CNG to curb pollution.
Delhi Sees Some Relief From Toxic Air; GRAP IV Removed, 'Will Bring Down Pollution In 5 Years,' Says Nitin Gadkari

Credits: iStock

Delhi finds itself in a little relief as the AQI of the city has dropped to 221 as per the CAQM. GRAP IV restrictions have also been lifted, however, pollution and smog continues to take over the city. The Meteorological Department has issued a yellow alert for the next few days, which could affect road and air traffic.

While GRAP IV is now removed, measures under GRAP I, II, and III will continue. As per the IMD forecast, this is what could happen for the next 5 days in Delhi

  • December 26: Dense fog will prevail in the morning. Visibility is likely to be low.
  • December 27: Yellow alert, dense fog in the morning and afternoon.
  • December 28: Yellow alert, moderate to dense fog expected in the early morning.
  • December 29-30: Fog will reduce slightly, but moderate haze will prevail in the morning.

Union Transport Minister On Delhi's Pollution

Nitin Gadkari, Union Minister of Road Transport and Highways also highlighted the alarming conditions of Delhi's smog and pollution. He said, "I stay for hardly two days in Delhi, and get an infection," as he spoke on how pollution impacts one's health conditions. However, he did speak on the severity of pollution and highlighted how the transport sector could play a huge role to bring relief to Delhi.

He highlighted that fuel combustion and transport emission leads to most of Delhi pollution.

In an interview with the news agency ANI, the minister also said that his ministry and Central Government are working on several projects and initiatives that will free Delhi from air pollution in the next five years.

Gadkari stated that the Ministry of Road Transport and Highways is undertaking projects worth Rs 1 lakh crore in Delhi to ease traffic congestion. He stated that all these efforts will not only help free Delhi of air pollution but also reduce the country's imports, increase job opportunities, and help farmers.

Electric Buses, Cars, and Scooters

The minister highlighted that 40% of the air pollution in the National Capital region is due to the burning of fossil fuels. In this regard, the government introduced electric buses in the city and enabled automakers to introduce electric cars and two-wheelers in the country.

He further stated that alternate fuel vehicles, such as those that run on CNG, LPG, and flex fuels (E20), are also being introduced and that all these efforts combined will reduce the city's pollution levels.

CNG And Bitumin From Rice Straw

Gadkari pointed out that nearly 200 lakh tonnes of rice straw or parali is burnt in Haryana and Punjab, a major cause of air pollution in the Delhi-NCR region. In this regard, the government is setting up 400 plants to convert the rice straw into CNG. At the moment, 60 plants are operational.

The minister also discussed a new project in Panipat in which rice straw is being used to create 1 lakh litres of Ethanol, 1.5 tonnes of bitumen, and 78,000 tonnes of jet fuel.

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Essential Tests Every Woman Should Go Through Before 2025 Ends

Updated Dec 25, 2025 | 06:00 AM IST

SummaryAs 2026 approaches, doctors urge women not to neglect year-end health checks. Annual gynecological screening helps detect silent issues like cervical changes, breast lumps, thyroid disorders, fertility concerns, vitamin deficiencies, and metabolic risks early. These tests support long-term health, informed family planning, and peace of mind.
Essential Tests Every Woman Should Go Through Before 2025 Ends

Credits: iStock

As the year draws to a close and 2026 approaches, most women find themselves juggling work deadlines, family responsibilities, and festive plans. In the middle of it all, personal health often slips to the bottom of the list. But doctors say this is exactly the time to pause and take stock of your body, especially your reproductive and hormonal health.

“Annual gynecological screening is one of the simplest ways to prevent silent illnesses, detect early changes, and understand your reproductive health better,” says Dr Tanveer Aujla, Consultant Obstetrician and Gynecologist at Motherhood Hospitals, Noida. Many common conditions show little to no symptoms in the early stages, making routine testing crucial.

Why yearly gynecological check-ups matter

Women often ignore subtle signs like fatigue, irregular periods, unexplained weight changes, or mood swings, assuming they are part of a busy lifestyle. According to Dr Aujla, this delay can be risky. “Conditions like cervical abnormalities, breast lumps, thyroid disorders, vitamin deficiencies, or hormonal imbalance often develop quietly and show symptoms only later,” she explains. A yearly check-up helps catch problems early and allows women to plan their health with confidence, especially if pregnancy is on the horizon.

Pap smear and HPV testing for cervical health

One of the most important screenings is the Pap smear combined with HPV testing. The Pap test looks for abnormal cells on the cervix, while the HPV test detects high-risk viruses responsible for most cervical cancers. “Together, they form a powerful screening tool,” Dr Aujla says. Women between 25 and 65 years should undergo this test every three to five years, or as advised by their doctor.

Breast screening for early detection

Breast health should never be overlooked. Dr Aujla advises yearly mammograms for women above 40, along with clinical breast examinations or ultrasound scans when needed. “These screenings help identify lumps, cysts, or early tissue changes,” she notes. She also stresses the importance of monthly self-examination to check for lumps, pain, or changes like inverted nipples.

Thyroid testing for unexplained symptoms

Thyroid disorders are extremely common in women and often remain undiagnosed. “A simple TSH, T3, and T4 test can explain symptoms like fatigue, mood swings, irregular periods, weight changes, or fertility issues,” says Dr Aujla. Early diagnosis can significantly improve quality of life and prevent long-term complications.

Fertility markers and preconception screening

Tests like AMH offer insight into ovarian reserve and help women plan their reproductive timelines. Dr Aujla points out that this is especially important for women with PCOS, irregular cycles, or delayed family planning. Preconception screening, which includes anemia levels, vitamin D, rubella immunity, blood sugar, and hormonal panels, ensures the body is prepared for a safe pregnancy.

Other essential health screenings

Women over 30 or those with a sedentary lifestyle should also get diabetes and cholesterol tests. Bone health panels checking calcium and vitamin D help prevent future osteoporosis. STI screening is equally important, as infections like chlamydia or gonorrhea can silently damage reproductive health if left untreated.

“Whether you are planning pregnancy or simply want to stay healthy, these tests offer clarity, confidence, and peace of mind,” Dr Aujla concludes. Taking time for these screenings before the year ends is a small step that can protect your health for years to come.

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Is Santa Claus Bad for Your Health? Here’s Why a Doctor Is Raising Concerns Ahead of Christmas

Updated Dec 25, 2025 | 02:00 AM IST

SummaryA public health doctor argues Santa Claus may harm health by promoting obesity, alcohol use, unhealthy food, and risky behavior. Writing in a medical journal, he notes Santa’s massive global influence, especially on children, despite no peer-reviewed evidence. He calls for a healthier Santa image rather than regulation or strict oversight.
Is Santa Claus Bad for Your Health? Here’s Why a Doctor Is Raising Concerns Ahead of Christmas

Credits: iStock

Santa Claus is bad for your health! This is a statement by Dr Nathan Grills, a Public Health Fellow in the Department of Epidemiology and Preventative Medicine, Monash University, Australia. Why is he saying this right ahead of Christmas?

Writing for an article in the British Medical Journal's Christmas issue (BMJ), he says, "Santa only needs to affect health by 0.1% to damage million of lives". He says it would be better if his popularity was rather used to promote healthy living.

Why Is Santa Claus Unhealthy?

Santa Claus's portrayal is where the concerns lie. This was not the first time someone has talked about. In fact, The Conversation in December 2024, talked about this exactly. If you look at Santa, he stands anywhere between 5'6" to 6'6" and weighs between 80Kgs to 136Kgs. He also carries a lot of weight around his belly, which, some may say, keeps him insulated as he sleighs through the snowy lands, but is sure overweight and obese. These portrayal promotes an unhealthy living.

Dr Grils also writes that Santa should rather share Rudolf's snack of carrots and celery sticks than brandy and mince pies, and swap his reindeer for a bike or a walk.

After reviewing existing literature and online sources to understand Santa Claus’s possible impact on public health, the analysis found no peer-reviewed studies directly addressing the issue. What did stand out, however, was the exceptionally high level of awareness of Santa among children. In fact, surveys of American schoolchildren showed that Santa Claus was recognized more widely than almost any other fictional character, second only to Ronald McDonald.

The doctor says that Santa is also used for selling products, which are mostly harmful, and this happens on global scale, which means, people get inspired. "Santa sells, and sometimes he sells harmful products. Like Coca-Cola, Santa has become a major export item to the developing world."

While Santa has been banned from smoking, but his images of enjoying a pipe or cigar are easily found on Christmas cards. The depiction of Santa does form a public perception, argues the doctor.

Dr Grill also notes that Santa may be promoting potential drink-driving, especially when someone follows the tradition to leave him a brandy to wish him well on his travels, while he has billion houses to visit.

Can Santa Spread Diseases?

child on Santa's lap (iStock)

Dr Grill says that he can spread diseases. If Santa sneezes or coughs around 10 times a day, all the children who sit on his lap may also end up catching the flu along with their Christmas presents.

Fit Santa (iStock)

However, it is important to note that these are views expressed by the doctor and no actual studies have been conducted on the same, Though Dr Grill does indicate for more research before calling for authorities to regulate Santa's activities. For now, Dr Grill proposes a new image for Santa, a healthier one. A slim Santa on a treadmill.

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