Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

For years, people have joked about how women seem to enjoy showers that could probably cook noodles. If you are someone who loves cranking up the water temperature until the bathroom looks like a steam room, you may have wondered whether there is an actual reason behind it. According to UK surgeon and content creator Dr Karan Rajan, the answer lies in biology. Women are not simply choosing scalding showers for fun. Their bodies are wired differently, and that affects how they experience temperature.

Higher Core Body Temperature

Dr Rajan explains that, on average, women have a slightly higher core body temperature than men. It might sound like this would keep them warmer, but in reality, it does the opposite. When the core is warm but the surrounding environment is cool, that contrast makes cold air feel even colder. So a mildly chilly room may feel more uncomfortable for women, leading them to turn to hotter showers to compensate.

This idea has gone viral online. In a popular TikTok clip, creator couple Micah and Sarah joked about preparing for a shared shower. Micah pretended to train for the extreme heat by dipping his hand in boiling water. The internet quickly chimed in with comments like “My husband says I am training for hell” and “He calls it lobster time”. The jokes were relatable because many couples experience this temperature divide, but not many knew the science behind it until now.

Hormones Add to the Chill

Hormones play a major role too. Estrogen affects blood flow to the extremities, which includes hands, feet and even earlobes. Research shows that women’s extremities can be up to three degrees colder than men’s. Dr Rajan points out that this becomes more noticeable during ovulation when estrogen levels peak. Women on hormonal birth control may also experience increased sensitivity because estrogen stays higher for longer periods.

So even when the core stays warm, the toes and fingers may feel unusually cold. A very warm shower becomes a quick and comforting fix for this temperature imbalance.

Lower Metabolic Rates

Another biological factor is metabolic rate. Women generally have a lower resting metabolic rate than men, meaning they produce less body heat throughout the day. This naturally makes them feel colder and more drawn to hotter water while bathing. Women also tend to have more body fat and less muscle mass, which influences how the body responds to temperature changes.

What Doctors Say

Australian GP Dr Jasmina Dedic Hagan supports these findings, as reported in Body and Soul. She explains that women typically have warmer cores, cooler skin, and a higher layer of insulating fat around the body. On top of that, they have reduced circulation in the extremities because the body prioritises keeping reproductive organs warm. With less muscle mass, the body’s heat-producing brown fat does not function in quite the same way as it does in men.

So Is It Just Preference?

Not entirely. While some women truly enjoy the sensation of a very hot shower, much of it is tied to biology. From hormones to metabolism to circulation, several factors work together to make warmer showers feel soothing and sometimes even necessary. So the next time someone teases you about loving lava-level water, you can tell them it is simply science at work.

When you are burning up, even a simple shower can feel confusing. Should you cool your body quickly with cold water or soothe your aches with something warm? Fever is a natural defense mechanism, but the symptoms it brings can make you feel miserable. The right water temperature can help ease discomfort and support your recovery.

Below is a simple breakdown of how fever affects your body, followed by practical shower tips and additional ways to safely bring your temperature down.

How Fever Resets Your Body’s Thermostat

During an infection, your immune system releases chemicals called pyrogens. These signals tell the hypothalamus, which is your internal thermostat, to raise your core temperature. The added heat slows the growth of certain viruses and bacteria and helps immune cells work more efficiently.

This temperature rise is why you feel:

• Chills as your body works to reach the new set point
• Sweating when the fever begins to settle
• Faster heart rate and quicker breathing, which increase fluid loss

Knowing this matters because water that is too cold can trigger intense shivering, which drives your temperature higher. Water that is too hot can widen your blood vessels and increase sweating, which may worsen dehydration.

Cold, Lukewarm, or Hot: Which Shower Helps Most?

Each water temperature works differently with a fever. Understanding these differences helps you choose what your body needs at that moment.

Cold showers cool your skin quickly. They may feel refreshing if you are overheated, but they often trigger shivering. That shivering can raise your core temperature and is especially risky in children.

Lukewarm or tepid showers are the safest choice for most people with fever. This temperature allows gentle heat loss through the skin without causing shivering. It helps you cool down gradually while keeping your body comfortable.

Warm or hot showers can help relieve muscle aches or sinus congestion, especially for adults. However, they can increase sweating and may slightly raise your temperature. Avoid them if you are already overheated or dehydrated.

Simple Shower Tips When You Have a Fever

• Start with lukewarm water to safely reduce temperature and ease discomfort.
• If you feel flushed and sweaty, splash cold water only on pulse points such as the wrists and neck.
• Use warm showers only for congestion relief and follow up with hydration and light clothing.
• If you feel dizzy, sit on a chair outside the shower and let steam fill the bathroom while you take a gentle sponge bath.

Other Safe Ways to Bring Down a Fever

Rest

Your body is already working hard to fight the infection. Light activity can raise your temperature further, so give yourself time to rest and recover.

Stay Hydrated

Fever increases the risk of dehydration, especially if you have vomiting or a poor appetite. Sip water, oral rehydration solutions, or electrolyte drinks. Chilled fluids can also help lower your temperature.

Stay Cool

Keep your room slightly cool and wear loose, breathable clothing. If you have chills, use a light blanket but avoid overheating. You can place a cool cloth on your forehead or under the arms for short intervals.

Medication

Over the counter fever reducers like acetaminophen and ibuprofen can safely lower fever. Always follow dosage guidelines. Avoid aspirin in children because it can lead to Reye's syndrome.

What Not to Do

• Do not take cold showers or ice baths because they trigger shivering and can raise your temperature.
• Avoid alcohol rubs since the alcohol can be absorbed through the skin.
• Do not take extra doses of fever medicine thinking it will work faster.
• Always read medication labels carefully to avoid accidental overdosing.

Turns out, kidney disease is not just a ‘kidney’ problem anymore, it can, in fact, affect other organs, and could even be linked to other chronic conditions, revealed a recent study.

In the US, more than 1 in 7 adults are affected by chronic kidney disease or (CKD). This means that 35.5 million Americans are affected by it, and what makes it worse is that 9 out of 10 people do not even know they have CKD, says the Centers for Disease Control and Prevention (CDC). Amid all these numbers thrown on to, something more concerning lies. A recent Lancet study shows a link between the rise in CKD and other chronic diseases. We are talking about chronic conditions like diabetes, high blood pressure, and obesity.

So, What Does The Study Say?

The researcher saw that 14 percent of adults who are over the age 20 or older, which makes 788 million Americans who had CKD in 2022. The biggest problem is not the disease itself, but the unawareness. Doctors, experts, and researchers from time and again have pointed out how kidney disease is often asymptomatic, this is why it is ignored until it becomes advanced. However, at that point the patients could already need dialysis or even an organ transplant. This gap in early diagnosis and treatment is what has made CKD the ninth leading reason of death, worldwide.

When you kidney functions naturally, it works as the powerhouse of filtration. A pair of healthy kidneys are able to filter and process more than 150 liters of fluid from the blood. These organs are also responsible for filtering out the waste and toxins through your urine. Not just that, but your kidneys also help in red blood cells production that keeps you healthy. When all of that does not happen, it can eventually impact every other organ in your body.

Like they say, everything is connected, and it surely is. For instance, somewhere around 20% of the blood that your heart pumps goes to your kidneys. If someone has diabetes and high blood pressure, it could damage the blood vessels and lead to protein in the urine and a slower filtration rate. It can then lead to other chronic infections, autoimmune disorders, and even genetic variants.

Kidney-Body Relation

If you leave your kidney disease untreated, it could lead to kidney failure. This is when you would be more in need of dialysis or a transplant. Doctors have pointed out that most people do not die of chronic kidney disease, rather it impacts their quality of life, worsening their cardiovascular conditions. It can lead to complications like a heart attack, a stroke, or a heart failure.

How Does This Happen?

People who have kidney diseases are at an increased risk for high blood pressure. Due to hurdles in the process of filtration, plaque build ups and hardens the arteries. This in return increases stress on the heart. In fact, the American Heart Association also defined the link between kidney and heart as 'cardiovascular-kidney metabolic syndrome'. This defines a health disorder that is a condition of the overlap of obesity, chronic kidney disease and cardiovascular diseases.

The bleed out of CKD is not just limited to your heart. The National Institute of Health, US points out that along with heart complications and high blood pressure, CKD could also lead to anemia, mineral and bone disorder, metabolic acidosis, malnutrition, and electrolyte imbalances in the blood.

So, What Is The Best Way To Keep Yourself Safe?

The first way is to note any symptoms and get yourself diagnosed. Look for signs like loss of appetite, unexplained nausea or vomiting. Do you feel tired often? Are you having trouble concentrating? Is there any change in how often you go pee?

Other symptoms like a change in your urine color or texture, or feeling itchy or dry, muscle cramps, unexplained weight loss or skin conditions could also signal towards kidney diseases.

However, not always does CKD show symptoms, experts suggest that to be one step ahead, it is important to undergo regular health checkups, including blood culture. General guidelines usually point towards getting a blood test done every 3 to 6 months. For someone with high blood pressure, diabetes or any other disease, the current guidelines say that those people should get regular blood and urine tests to screen for kidney disease. But what really happens is that though these tests exist, they are still used far too little. Doctors point out that many patients skip them because collecting a urine sample feels inconvenient, and overall awareness about kidney disease remains low. As a result, research shows that only about 35 percent of people with diabetes, and just 4 percent of those with high blood pressure, actually end up getting the recommended urine screening.

A ray of hope is that there are now several effective tools to slow the progression of kidney disease. Along with traditional options like ACE inhibitors, newer classes of medications including certain heart failure drugs and GLP-1 drugs. These medicines have shown to help protect kidney function. Although these newer treatments are not widely used yet, their adoption is steadily increasing.

What is important to remember is to also always consult your GP to ensure all preventative measures are followed carefully.