What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Updated Dec 3, 2024 | 06:13 PM IST

SummaryDid you know type 3 diabetes, linked to insulin resistance in the brain, is associated with Alzheimer’s disease? It highlights how metabolic disorders can affect memory, cognition, and brain health.
What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

What Is Type 3 Diabetes? Insulin Resistance In The Brain That Could Trigger Alzheimer’s

Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

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Times Network India Health Summit 2026 Key Takeaways: AI, Fertility, AYUSH, Cancer Care & More

Updated Oct 28, 2026 | 11:57 PM IST

SummaryThe Times Network India Health Summit 2026 featured several informative and insightful knowledge sessions and panel discussions on subjects like AI in healthcare, advancement in healthcare technologies, AYUSH, cancer care and more.
Times Network India Health Summit 2026 Key Takeaways: AI, Fertility, AYUSH, Cancer Care & More

Credit: Times Network

The Times Network India Health Summit 2026 brought together policymakers, clinicians, researchers and healthcare industry leaders to discuss the future of India's healthcare system, with conversations spanning medical innovation, access to treatment, mental health, women's health and preventive care.

The third edition of the Times Network India Health Summit & Awards was held in New Delhi on October 28 under the theme, The Blueprint for a Future-Ready Healthcare Ecosystem: Innovation. Access. Self-Reliance.

From the use of artificial intelligence (AI) in diagnostics to advances in fertility treatment and the need to strengthen public health infrastructure, various sessions explored several aspects of how healthcare delivery could evolve. Here are the key discussions and takeaways from the summit.

Anupriya Patel Highlights India's Healthcare Priorities Including Ayushman Bharat Coverage

Union Minister of State for Health and Family Welfare Anupriya Patel addressed the summit on building a future-ready healthcare ecosystem. With around 500 Ayushman Bharat cards issued, Patel also said that 132.5 million people had received free treatment under the scheme.

She also addressed India's Viksit Bharat 2047 vision, stating that Union health budget increased from around Rs 37,000 crore in 2014 to more than Rs 1.06 lakh crore.

Also read: Infertility Affects 1 In 6 Couples: Experts Highlight Age, IVF Costs & Male Fertility At Times Health Summit 2026

Delhi Health Minister Dr. Pankaj Singh Addressed Air Pollution Crisis

Delhi Health Minister Pankaj Singh answered key questions about the city’s looming air pollution crisis. He said that the government's various pollution-control measures, including electric vehicle (EV) policy can help fight it. He also spoke about the need for long-term solutions.

Union Minister of State (Independent Charge) AYUSH Prataprao Jadhav, Madhya Pradesh Minister of State Narendra Shivaji Patel and Uttarakhand Cabinet Minister Subodh Uniyal, were also scheduled to address different aspects of healthcare policy and delivery.

Padma Bhushan Dr S K Sarin On Liver Health

Padma Bhushan Dr Shiv Kumar Sarin, leading hepatologist, gastroenterologist, and medical educator who also serves as the Senior Professor, Chancellor, and Director of the Institute of Liver and Biliary Sciences (ILBS), recently spoke about the dos and don’ts to maintain a healthy liver at the Times Health Summit 2026.

From ideal breakfast time to late night eating, the expert spoke about common lifestyle mistakes people make that could worsen their liver health.

Also read: Unspoken Side Of Breast Cancer: Experts Discuss Recurrence Risk, Emotional Toll & Societal Impact At Times Health Summit 2026

Need For Investment In Ayurveda & AYUSH Sector

The session From Tradition to Therapeutics: The New Science of AYUSH was based on the role of traditional medicine in India's healthcare landscape.

Dr Biswaroop Roy Chowdhury, Founder of BRC Clinics Health, and Dr Tanmay Goswami, Founder of Goswal, discussed Ayurveda, its potential applications and questions surrounding its integration with modern medicine.

The speakers spoke about Ayurveda’s scientific research, evidence, AYUSH funding, clinical applications and integration with western medicine. The experts said that Ayurveda sector is valued at approximately $17–18 billion, while China's traditional medicine sector is estimated at around $30 billion, calling for greater investment in the sector.

Mental Health: Suicide Risk, Screen Addiction & More

Mental healthcare was another focus, with Dr Deepak Kumar, Professor and Head of the Department of Psychiatry at the Institute of Human Behaviour and Allied Sciences (IHBAS), discussing The Next Frontier in Indian Psychiatry: Specialization, Geriatric Mental Health, and De-addiction Strategies.

The doctor discussed immediate threat of suicidal thoughts, warning behavioural signs, screen addiction and need for parents to supervise and limit screen use in children.

Also read: Leading Gastroenterologist Padma Bhushan Dr S K Sarin Shares Dos & Don’ts For Healthy Liver At Times Health Summit 2026

Aftermath Breast Cancer Diagnosis & Treatment

Women's health was featured prominently at the summit, with the knowledge session Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes.

The session featured Dr Meenu Walia, Chairman of Medical Oncology at Max Healthcare; Vaishali Iyer, Country Head of Communications, Patient Advocacy and CSR at Novartis in India; and Dr Pankaj Goyal, Senior Consultant and Unit Head of Medical Oncology at Rajiv Gandhi Cancer Institute.

The experts focused on the risk of recurrence, the emotional toll of breast cancer treatment, financial and societal hardships, body image issues, intimacy problems and other challenges patients face after leaving the hospital.

Fertility Treatment And Parenthood

The panel The Fertility Revolution: Reimagining Parenthood in Modern India spoke about the evolving field of reproductive medicine and the challenges faced by people seeking fertility treatment.

The speakers included Dr Ranjana Sharma, Senior Consultant in Obstetrics and Gynaecology at Indraprastha Apollo Hospital; Dr Vimal Grover, Senior Director of Obstetrics and Gynaecology at Fortis LaFemme; Dr Hrishikesh Pai, Founder and Managing Director of Bloom IVF India; and Dr Abha Majumdar, Emeritus Consultant in IVF and Human Reproduction at Sir Ganga Ram Hospital.

The session brought attention to fertility preservation, IVF costs, male infertility, stigma women face, and the judgments that come with seeking IVF for starting a family.

Also read: Experts Discuss Ayurveda For Treating Lifestyle Disorders, Medical Emergencies & Trauma At Times Health Summit 2026

Why Menopause Is A Long-Overlooked Health Issue

The session From Silence to Care: Why India Can No Longer Ignore Menopause focused on menopause and the need to bring greater attention to women's health during midlife.

The session was led by Sanjith Shetty, Founder and CEO of Miror. He spoke about the suicide rates among menopausal women, along with other life challenges like divorces, retirements, and social isolation.

Digging Deeper Into Longevity Science

The fireside chat From LifeSpan to HealthSpan: Can Science Help Us Live Longer and Better? explored the science of longevity and the difference between living longer and maintaining good health for more years.

The conversation featured Dr Chirantan Bose and Dr Preetesh Bhandari, founders of Vytalyou. They spoke about the importance of maintaining muscle health, monitoring neurological health, and warding off lifestyle diseases like obesity and diabetes.

Other Sessions

The role of technology in modern medicine was explored in Precision Diagnostics: AI, Genomics & The New Era Of Personalized Care. The panel featured Dr Arjun Dang, CEO and Partner at Dr Dangs Lab; Dr Manish Vaish, Director and Head of the Institute of Neurosciences at Medanta, Noida; and Dr Belal Bin Asaf, Director of the Institute of Chest Surgery, Chest Onco-Surgery and Lung Transplant at Medanta, Noida.

The discussion focused on the evolving role of artificial intelligence and genomics in diagnostics, personalised treatment and improving diagnostic accuracy.

The future of specialised medical services was examined in The Next Frontier of Advanced Care: Scaling Capacity, Innovation & Clinical Excellence. The session brought together Dr V.S. Chauhan, Chairman and Managing Director of Prakash Hospitals and Institutions, and Prof. Dr Sanjeev Bagai, Chairman of Nephron Clinic.

The discussion centred on expanding advanced healthcare capacity, strengthening clinical excellence and leveraging innovation and technology to improve patient outcomes while making specialised treatment more accessible.

Addressing the challenges of equitable healthcare delivery, Reengineering Public Health Infrastructure: Last-Mile Delivery, Digital Health Equity, and Rural Access brought together Dr Anoop Saraya of the Institute of Liver & Biliary Sciences; Dr Charu Dutt Arora of AmeriHealth Home Healthcare, Asian Institute of Medical Sciences; Dr Gyanendra Kumar of Maulana Azad Institute of Dental Sciences; Girish Krishnamurthy, CEO of Tata Medical & Diagnostics; and Dr Jyoti Wadhwa of Apollo Athenaa Women's Cancer Centres.

The session focused on strengthening public health infrastructure, improving rural and last-mile access, and exploring the role of digital health and healthcare delivery models in bridging gaps in access to medical services.

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Unspoken Side Of Breast Cancer: Experts Discuss Recurrence Risk, Emotional Toll & Societal Impact At Times Health Summit 2026

Updated Oct 28, 2026 | 08:59 PM IST

SummaryAt the Times Network India Health Summit and Awards 2026 in New Delhi, experts discussed the aftermath of breast cancer diagnosis and treatment.
Unspoken Side Of Breast Cancer: Experts Discuss Recurrence Risk, Emotional Toll & Societal Impact At Times Health Summit 2025

Credit: Times Network

The journey of a breast cancer patient does not end when their treatment comes to a conclusion. There is always a risk of recurrence, which makes regular follow-ups and adherence to treatment important.

At the Times Network India Health Summit and Awards 2026 in New Delhi, a panel formed by Dr Priya Parmar, Chief Operating Officer, Indian Cancer Society, Delhi, Dr. Jyoti Wadhwa - Principal Lead of Medical and Precision Oncology, Apollo Athena Women’s Cancer Centres, New Delhi and Apollo Hospital, Gurgaon, Dr. Meenu Walia, Chairman Medical Oncology, Max Healthcare, Dr Pankaj Goyal, Sr Consultant and Unit Head, Medical Oncology, RGCI, and Vaishali Iyer, Country Head, Communications, Patient Advocacy and CSR, Novartis in India, discussed the big picture after breast cancer treatment.

During a panel discussion titled “Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes,” experts highlighted the physical, emotional, social and financial challenges that women may continue to face after treatment among many more.

What Comes After Breast Cancer Treatment?

For many women, the period after breast cancer can involve more than medical monitoring. They may face fatigue, menopausal symptoms and changes in body image after undergoing a major physical change, while concerns about intimacy, fertility and relationships can affect emotional and mental well-being.

Dr. Priya Parmar highlighted how losing a breast or hair can affect a woman's sense of identity and femininity. Some survivors also face social stigma related to marriage and fertility, while sexual health and relationship concerns may remain difficult to discuss.

The burden can be greater for women who lack family support or have limited financial resources. These circumstances may affect not only emotional recovery but also their ability to attend follow-up appointments and continue treatment.

The financial strain can become particularly difficult if cancer returns and further investigations or treatment are required.

Dr. Meenu Walia said that treatment for advanced disease can add to the economic burden faced by patients and their families.

Also read: Vanessa Trump Recovers From 'Very Invasive' Breast Cancer, Reveals Early Sign Of The Disease

Risk Of Recurrence

The risk of breast cancer recurrence is not the same for every patient. It depends on the cancer's stage and subtype, tumour grade, lymph node involvement, response to treatment and whether treatment is timely.

Dr. Jyoti Wadhwa explained that different breast cancer subtypes can follow different recurrence patterns.

Triple-negative breast cancer tends to recur earlier, often within the first two to three years after treatment. Hormone receptor-positive, HER2-negative breast cancer, however, can return even 10 to 20 years later.

She also said that patients who achieve a pathological complete response after treatment given before surgery may have a lower risk of recurrence than those with residual disease.

However, a lower estimated risk does not mean the risk is eliminated. Continued monitoring is important even for patients who have responded well to treatment.

Also read: Beyond the Lump: Overlooked Breast Cancer Symptoms That Can Delay Diagnosis

Feeling Better Is Not A Reason To Skip Follow-Ups

One concern raised by the experts was that some patients stop taking prescribed oral hormone therapy or miss appointments after their symptoms improve.

“Your first attempt at treatment is always your best attempt,” Dr. Walia said, underlining the importance of appropriate diagnosis and treatment from the outset.

Follow-up care helps doctors monitor a patient's recovery, assess treatment-related effects and make decisions based on individual clinical circumstances. The appropriate schedule and any further treatment depend on the patient's diagnosis, risk profile and medical history.

Experts also cautioned against allowing the possibility of recurrence to dominate a survivor's life. Understanding individual risk should help patients make informed decisions, rather than leave them in constant fear that cancer will return.

Post-Treatment Care Needs More Than Medical Monitoring

The long-term effects of breast cancer also have implications beyond the individual patient. Vaishali Iyer, Country Head of Communications, Patient Advocacy and CSR at Novartis in India, highlighted an estimated 140 million productive hours lost due to breast cancer care, drawing attention to its wider economic impact.

Dr. Wadhwa emphasised the need to address treatment-related concerns, including menopausal symptoms and bone health, which may require attention even after primary cancer treatment has ended.

Dr. Pankaj Goyal, Senior Consultant and Unit Head of Medical Oncology at RGCI, stressed that doctors must build trust with patients and explain recurrence risks without causing unnecessary alarm. Discussions about care should also account for patients' personal circumstances and financial constraints.

The panel discussion, titled “Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes,” took place at the Times Network India Health Summit and Awards 2026.

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Leading Gastroenterologist Padma Bhushan Dr S K Sarin Shares Dos & Don’ts For Healthy Liver At Times Health Summit 2026

Updated Oct 28, 2026 | 04:02 PM IST

SummaryPadma Bhushan Dr Shiv Kumar Sarin spoke about lifestyle habits that could worsen liver health at the Times Health Summit 2026.
Leading Gastroenterologist Padma Bhushan Dr S K Sarin Shares Dos & Don’ts For Healthy Liver At Times Health Summit 2026

Credit: Times Health Summit 2026

Padma Bhushan Dr Shiv Kumar Sarin, leading hepatologist, gastroenterologist, and medical educator who also serves as the Senior Professor, Chancellor, and Director of the Institute of Liver and Biliary Sciences (ILBS), recently spoke about the dos and don’ts to maintain a healthy liver at the Times Health Summit 2026.

Held under the theme “The Blueprint for a Future-Ready Healthcare Ecosystem – Innovation. Access. Self-Reliance,” the summit brought together healthcare professionals and industry stakeholders to discuss innovation, access to treatment and policy approaches shaping India's healthcare sector.

Should You Drink Hot Water In The Morning For Bowel Movement?

The doctor addressed the daily morning ritual of drinking hot water in the morning, which a lot of people follow to release bowels.

Dr Sarin said, “Don't use hot water or anything for that matter to make you go to the toilet because it is the connection between the brain and the bowel that is very important.

He also spoke about opting for other drinks like coconut water or lemon water with honey. He said that lemon can help improve iron absorption in your body.

He added, “As per coconut water is concerned, it has potassium which is very good for your bowel health but it should still not be an everyday thing. For nimbu and honey, you should remember that honey has fructose. So if you are consuming honey, you also need to churn that out."

Also read: Fatty Liver Disease: Scientists Identify 5 Subtypes With Different Health Risks

Ideal Time for Breakfast

Many of us do not know what is the right time for breakfast. It is especially important as eating after fasting for eight to ten hours affects your energy and metabolic health throughout the day.

Dr Sarin said, "It's after sunrise. Minimum 12 hours after the last food that you have eaten. Ussay pehle galti nahi kariyega khaanay ki. Let the stomach, and the bacteria and the intestine recover."

He also spoke about whether you should have fruits for breakfast. "Breakfast should be fruits. And, low calories fruits. Avoid carbs."

Also read: The Changing Obesity Treatment Landscape: Where Does Bariatric Surgery Fit in the Age of Weight-Loss Drugs?

How Coffee Affects The Liver

There is a lot of information as well as misinformation about coffee consumption and liver health. Dr S K Sarin spoke in its favour and said that it could prevent a lot of liver conditions.

He said, "It does many things. it clears several toxic things including fat, clears the flow of bile, good enzyme inducer, prevents fibrosis of the liver and can decrease cirrhosis and also the development of liver cancer."

He also warned ignoring healthy dietary habits and simply relying on coffee is also not ideal. He added, "Coffee is not medicine, it is something which can help you prevent and not treat."

Is Your Lunch Completely Healthy?

Dr Sarin also warned against eating more amount carbohydrates than the recommended limit. He explained how sitting next to an obese person can make you feel physically lethargic as their breath may emit endogenous alcohol.

When you eat a carbohydrate-heavy meal, your digestive system breaks down carbohydrates into sugars. Certain microorganisms in the gut, including yeasts and some bacteria, can ferment these sugars and produce small amounts of ethanol, or alcohol. This is known as endogenous alcohol production.

Dr Sarin recommends eating low-carb meals for lunch like sprouts, vegetables, yoghurt, buttermilk or low-sugar fruits.

Late-Night Eating Is A Red Flag

Dr Sarin recommends having dinner before sunset. He also said that having late-night dinners could disrupt your sleep.

He added, "Obesity during youth increases the risk of heart disease later in life. After the age of 40, eating one meal a day may have health implications. The total daily calorie intake should not exceed 300–400. Avoid eating late at night. Eating late can also affect your insulin resistance."

Yearly Screening To Keep Liver Health In Check

Dr Sarin also said that thin people can also have unhealthy fat that may cause fatty liver. He recommended yearly screens to keep liver health in check.

He said, "Even thin people can have excess body fat and low muscle mass, which may affect their health. Being thin does not necessarily mean being healthy. Maintaining good muscle mass is important."

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