Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

India has recorded 6,927 dengue cases and 10 deaths so far in 2026, according to the latest data from the National Centre for Vector Borne Diseases Control (NCVBDC).

According to the provisional data as of February this year, Tamil Nadu reported the highest number of cases at 2,873, followed by Maharashtra with 786, Kerala with 670, Karnataka with 560, and Andhra Pradesh with 448 cases. During the same period, Kerala reported nine deaths, while Tamil Nadu reported one death.

According to the Ministry of Health, the Case Fatality Rate (deaths per 100 cases) for dengue has remained below 1 per cent since 2008 and stood at 0.13 per cent in 2024.

The dengue burden in India has steadily increased over the past few years:

National Dengue Day: History And Theme

Launched in 2010, National Dengue Day is observed every year on May 16 as a pre-monsoon alert to help communities prepare before mosquito breeding peaks.

“On National Dengue Day, let us unite to spread awareness about dengue prevention and keep our surroundings clean and safe. The Government of India continues to strengthen dengue control through better surveillance, testing, improved treatment, and awareness campaigns,” said Jagat Prakash Nadda on the social media platform X.

“This year’s theme, ‘Community Participation for Dengue Control: Check, Clean and Cover,’ reminds us that community action is key to defeating dengue,” he added.

Dengue Vaccines In India

Notably, India is currently developing an indigenous dengue vaccine that is undergoing clinical trials.

“The trials will take at least two and a half years, which means by the end of 2028, we will have the results,” said Dr. N K Arora, Member of the National Technical Advisory Group on Immunization in India (NTAGI), speaking to HealthandMe.

He highlighted the severity of dengue when it progresses from a mild illness to a severe one, particularly among young adults.

The vaccine is expected to play a crucial role in protecting the 10–20 age group, which is considered more susceptible to severe dengue cases.

Also read:Ebola Resurfaces In Eastern DR Congo In 17th Outbreak, Claims 65 Lives: All You Need To Know

“We are waiting for the results of the trials, and once the vaccine is recommended by the NTAGI, the system will be ready to adopt it,” Dr. Arora added.

Meanwhile, Qdenga, a dengue vaccine developed by the Japanese pharmaceutical company named Takeda Pharma, is expected to be rolled out soon in the country.

The vaccine TAK-003 will be available in India through a manufacturing partnership with Hyderabad-based Biological E (Bio E), in line with the 'Make in India' initiative.

What Is Dengue?

Dengue is a viral infection transmitted primarily by Aedes mosquitoes and is common in tropical and subtropical regions worldwide.

Mild dengue causes high fever and flu-like symptoms. However, in some cases, it can progress to severe dengue, also known as dengue hemorrhagic fever, which may lead to serious bleeding, shock, and death.

Dengue is considered the most prevalent viral infection transmitted by Aedes mosquitoes. More than 3.9 billion people across over 132 countries are at risk, with an estimated 96 million symptomatic cases and around 40,000 deaths annually worldwide.

Symptoms Of Dengue Fever

Symptoms usually appear 4–10 days after being bitten by an infected mosquito and may vary in severity. Common symptoms include:

• High fever
• Severe headache
• Pain behind the eyes
• Joint and muscle pain
• Nausea and vomiting
• Fatigue
• Skin rashes appearing a few days after fever onset

In severe cases, dengue may cause excessive bleeding, a sudden drop in blood pressure, and organ complications.

How To Prevent Dengue

Preventing dengue mainly involves reducing mosquito exposure and eliminating mosquito breeding sites. Effective preventive measures include:

• Using insect repellents containing DEET
• Wearing long-sleeved clothing, especially during dawn and dusk
• Installing screens on windows and doors
• Using mosquito nets while sleeping in endemic areas
• Eliminating stagnant water in flower pots, gutters, and containers
• Using mosquito traps or insecticide-treated materials in mosquito-prone areas.

While alcohol consumption is known to be harmful to health, a new study has linked it to 62 disorders ranging from heart and digestive diseases to mental and neurological conditions and cancers.

The study, published in the journal Addiction, showed that the fully alcohol-attributable conditions are mainly grouped under non-communicable diseases and injuries. These include endocrine, nutritional, and metabolic diseases, mental and behavioral disorders, diseases of the nervous system, diseases of the circulatory system, such as alcoholic cardiomyopathy, and digestive diseases, including alcoholic liver disease and cirrhosis.

The latest data also adds psychotic disorders, gastritis, ulcers, pancreatitis, fatty liver disease, pregnancy- and perinatal-related conditions such as fetal alcohol syndrome and fetal alcohol spectrum disorders, as well as external causes and injuries, including alcohol poisoning.

“These conditions are 100 per cent alcohol attributable, meaning these diseases would not even exist in the world without alcohol use,” said Jürgen Rehm, senior scientist at the Institute for Mental Health Policy Research in Toronto and part of the study team, according to CNN.

“There are another 30 diseases in which alcohol plays a role, such as breast and other cancers, heart disease, stroke, diabetes, and dementia,” Rehm said. “These diseases would exist even without alcohol use, but alcohol use is responsible for a certain proportion of them.”

How The Study Identified Alcohol-Related Diseases

The diseases and injury categories fully attributable to alcohol were identified using the World Health Organization (WHO) International Statistical Classification of Diseases and Related Health Problems, 10th (ICD-10) and 11th (ICD-11) revision databases.

The study defines heavy drinking as more than 40 g of pure alcohol a day for women and 60 g a day for men. This translates to about 1.4 ounces of liquor for women and 2.1 ounces for men.

The good news, researchers said, is that many of these health effects can be slowed, stopped, or even reversed.

“Fortunately, the immediate effects of alcohol on the immune system don’t last long. Depending on levels of consumption, the body bounces back within days to a week,” Rehm said.

Alcohol And Cancer Risk

Also read: Antidepressant Use During Pregnancy Not Linked To Autism, ADHD, Finds Lancet Study

In 2025, former US Surgeon General Dr. Vivek Murthy released a new Surgeon General Advisory on alcohol and cancer risk, highlighting the direct link between alcohol consumption and increased cancer risk.

Similar to warning labels on cigarettes, the Surgeon General called for cancer risk warnings on alcohol products.

The report released by the US Surgeon General’s office identified at least seven types of cancer associated with alcohol consumption. It also recommended updating alcohol labels to include cancer warnings and reassessing guideline limits for alcohol consumption.

The cancers linked to alcohol consumption that Murthy recommended should be included on warning labels:

• Breast cancer
• Colon cancer
• Throat cancer
• Liver cancer
• Voice box cancer
• Esophageal cancer
• Mouth cancer.

Amid India's growing burden of high blood pressure among the youth, Prataprao Jadhav, Union Minister of State (I/C), Ministry of Ayush and Minister of State for Health and Family Welfare, said hypertension is emerging as a major public health concern due to worsening lifestyle habits.

High blood pressure is a “silent killer” that is rapidly increasing among India’s youth because of unhealthy lifestyle changes, the minister said.

Hypertension Rising Rapidly Among Young Indians

Ahead of World Hypertension Day 2026, Jadhav noted that the condition often progresses without visible symptoms and can eventually lead to severe complications such as heart attacks and strokes.

“In today’s time, it is essential that we make our communities more sensitive and aware and strengthen awareness about hypertension. Due to changing lifestyles and reduced attention to physical and mental health, hypertension is rapidly increasing even among the youth,” Jadhav said in a video message during the ‘Illness to Wellness Conference on Transforming Hypertension Care: Prevention to Wellness’ organized in the national capital.

He highlighted that the Government of India, under the National Program for Prevention and Control of Non-Communicable Diseases (NPCDCS), is actively promoting population-based screening, early detection, and management through Health and Wellness Centers across the country.

Modern Lifestyle Habits Increasing Hypertension Risk

Prof. Rakesh Yadav, Cardiologist and head of the Department of Emergency Medicine at AIIMS, New Delhi, stated that once known to be the disease of the elderly, hypertension is now more common among the youth. The reason — lifestyle changes, the experts said.

“The biggest problem is that despite increasing awareness, people still do not monitor their blood pressure regularly or continue treatment consistently. Hypertension is no longer limited to the affluent or elderly; it is now affecting all sections of society, including children and young adults,” said Prof. Rakesh Yadav, Cardiologist and head of the Department of Emergency Medicine, AIIMS, New Delhi.

“Obesity remains one of the major underlying causes, and regular monitoring of blood pressure and sugar levels, affordable lifelong medication, healthy dietary practices, and weight management are essential to reducing mortality associated with hypertension and related diseases,” he added.

In India, more than 1 in 4 people have hypertension, and cumulatively, more than 90% of adults with hypertension are either undiagnosed, untreated, or treated but live with uncontrolled hypertension.

Experts at the conference also pointed out that modern lifestyles marked by long working hours, constant connectivity, poor sleep, sedentary habits, and rising stress levels are significantly contributing to the growing burden of hypertension and other lifestyle disorders.

Another major concern, they said, is that many people tend to ignore early symptoms until complications arise, negatively affecting treatment outcomes.

“Hypertension is one of the biggest public health challenges today because most people do not take it seriously until complications arise. Nearly one in four adults is affected by hypertension, yet awareness and blood pressure control remain very low,” said Dr. Ripen Gupta, Vice Chairman & Unit Head - Cardiology, Max Smart Super Speciality Hospital, Saket.

Rajesh Bhushan, Former Secretary, Ministry of Health & Family Welfare, said high blood pressure is not limited to urban populations and is increasingly affecting youth in rural India as well.

“The problem of hypertension is as prevalent in rural India as it is in urban India, but because we live in metro cities, we often believe it is only an urban problem. Early detection is extremely important because without early detection, early treatment becomes difficult,” Bhushan said.

Experts Stress Early Detection And Preventive Care

Bushan stated that non-communicable diseases impact GDP significantly across countries, and therefore, prevention and timely intervention are critical.

Hypertension should never be taken lightly, said Dr. Sanjeev Singh, Chairperson, FICCI Medical Education Task Force and Medical Director, Amrita Institute of Medical Sciences & Research Centre. He urged people to follow medical advice seriously to avoid long-term complications.

The doctors called for critical lifestyle interventions for prevention and management. This included:

• annual BP screening,
• aerobic exercise,
• resistance training,
• reduced desk time,
• proper sleep,
• yoga,
• meditation,
• monitoring BMI and waist circumference.