Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

A 31-year-old Brazilian beauty queen, Maiara Cristina de Lima Fiel, has reportedly died after suffering a sudden heart attack.

de Lima Fiel, a young mother, was due to compete in a beauty pageant next week. She reportedly had no major health issues. Paramedics spent more than an hour trying to save her life but she tragically did not recover, The Daily Mail reported.

Her untimely death has sparked grief and shock among her community and followers, and has also reignited concerns over unexpected cardiac events in seemingly healthy individuals.

Who Was Maiara Cristina de Lima Fiel?

de Lima Fiel was crowned Miss Londrina last year in a prestigious regional beauty pageant and also came runner-up in the 2025/26 edition of Miss Sarandi, The Daily Mail reported.

"She was such a committed, dedicated young woman," the report quoted Vitor Tavares, organizer of the contest Maiara, as saying. She was due to compete on April 29.

"I had the pleasure of meeting her in person at the end of last year when she confirmed her participation as Miss Londrina. From that moment, it was clear how seriously she took this dream," he added.

While detailed medical circumstances have not been publicly disclosed, such sudden cardiac events in young adults are often linked to underlying, sometimes undiagnosed, heart conditions or acute cardiovascular episodes.

Also read: US Cardiologist Explains Why 2026 AHA Cholesterol Guidelines Recommend Starting Young

Heart Attacks Rising Among Younger Adults

Acute coronary syndromes, or heart attacks, are on the rise among young adults.

While there are some genetic predispositions for premature heart attacks, the majority of the risk is attributed to the increased incidence of conventional risk factors in young people, such as

• Obesity,
• Sedentary lifestyle,
• Diabetes,
• Hypertension,
• Dyslipidemia
• Smoking
• Substance abuse.

Who Is At Risk for Sudden Heart Attacks?

Also read: Ideal Blood Pressure Reading for Older Adults: Harvard Health Experts Have an Answer

Doctors are now seeing them in people as young as their late 30s and early 40s, especially those with high-stress jobs.

“They mistake early signs for lifestyle issues: acidity after a heavy dinner, shoulder pain from sitting at a laptop, or tiredness from long hours," Pankaj Vinod Jariwala, Interventional Cardiologist at Yashoda Hospitals, told HealthandMe.

Dr Krunal Tamakuwala, cardiologist at KD Hospital, Ahmedabad, pointed out that the real danger is not that these heart attacks are completely "symptomless," but that their symptoms are so common that they are easily ignored.

By the time a person finally sees a doctor, their heart may already be seriously damaged.

“Sometimes, it arrives silently, hidden behind complaints we consider minor. That is why doctors urge patients not to ignore symptoms that linger or feel unusual, even if they seem harmless at first,” Dr Tamakuwala told HealthandMe.

How To Reduce Heart Disease Risk In The 30s?

The experts shared that to boost heart health, the key is to

• Eat a healthy and balanced diet
• Avoid refined sugars, fats, and processed foods.
• Do at least 30 minutes of moderate physical activity per day, for five days a week.
• Stay away from smoking,
• Early screening and treatment
• Improving mental health.

Body odour is natural, but sometimes it may signify a health issue. When body odour is persistent, unusual, and/or changes suddenly, it could indicate a possible health problem. Sweat itself is odourless, but when it interacts with bacteria on the skin, it creates the odour that we associate with body odour. Some of the factors that may alter the way the body smells are medications, hormones, and lifestyle choices. Dr Pooja Kanumuru, a dermatologist at Apollo Clinic, Indiranagar, addressed this for Health and Me.

What does body odour indicate?

There are medical conditions that can cause body odour to be unusual or excessive: bromhidrosis; bacterial and/or fungal skin infections; and systemic diseases such as diabetes, liver disease, and kidney disease. For example, a diabetic with poor management may have a fruity-smelling body odour, whereas an infected person may have a foul body odour due to bacterial activity.

Body odour becomes an issue when there is no improvement despite proper hygiene. If body odour is associated with other symptoms such as fatigue, unexplained weight loss, fever, and/or abnormal skin changes, these should be addressed to determine the cause and seek appropriate assistance. Medically associated body odour does not decrease with normal methods such as bathing and/or the use of deodorants but tends to persist.

Factors that affect body odour

Body odour can also be affected by the following:

Hormonal and metabolic changes during certain periods of life (for example, puberty, menstruation, pregnancy, and menopause) can change the amount of sweat produced, which can also alter the intensity of its smell.

Thyroid disorders, especially hyperthyroidism, can sometimes result in increased sweating.

Rare metabolic disorders, such as trimethylaminuria, can result in a strong, fishy-smelling body odour due to the inability to break down certain substances in the body.

Clinical insights of body odour

It is interesting how certain unusual odours can offer important clinical insights. For example, if a person has a fruity odour, this could indicate difficulties with diabetes control. A fishy smell could be a sign of a metabolic disorder, while an ammonia-like smell may indicate problems with kidney function. Meanwhile, musty or foul odours may suggest an infection or liver dysfunction. While these odours cannot be used as stand-alone diagnoses, they can help guide further medical evaluation.

Lifestyle changes to improve body odour

Diet and lifestyle choices significantly affect body odour. For example, foods such as garlic, onions, spicy foods, red meat, and alcohol can exacerbate body odour, while poor hydration, high stress levels, smoking, and obesity can worsen it further. Additionally, wearing very tight or non-breathable clothing may cause perspiration and bacteria to become trapped, thereby worsening body odour.

Keeping your body clean, applying the right type of antiperspirant, wearing breathable materials, and maintaining a healthy diet can all help in managing body odour. However, if body odour persists or worsens, you should consult a doctor. A prompt medical assessment can identify the cause and allow your physician to discuss possible treatments, including topical medications and procedures that reduce excessive sweating.

The human skin is the body's largest organ, a dynamic barrier spanning roughly 1.7 square meters in the average adult. It blocks pathogens, regulates temperature, and signals systemic distress.

What compromises this barrier most reliably are decisions made in the course of an ordinary day; how a body is cleaned, what materials rest against it for hours, and whether moisture is managed or ignored

Most skin infections, rashes, and fungal conditions during primary care can be prevented. They develop when the skin is exposed to moisture, friction, or microbes for extended periods, which weakens its natural protective barrier. Once this barrier is compromised, bacteria, fungi, and irritants can take hold. Seeing it this way makes hygiene a matter of health, not just routine care.

Moisture, Friction, and Microbial Load: The Three-Factor Model

Many skin conditions linked to hygiene arise from a combination of factors, including excess moisture, repeated friction, and unchecked microbial growth.

Moisture, whether it is from sweat, urinary leakage, or inadequate drying after bathing, softens the stratum corneum, the protective outermost layer.

Softened skin abrades under friction far more readily than dry skin. In zones like the groin, underarm, and the skin folds of infants, this combination creates ideal conditions for intertrigo, candidal infections, and bacterial folliculitis.

Infants represent the most vulnerable case study. Diaper dermatitis, affecting a significant proportion of children at some point in infancy, develops when occlusive material holds urine and stool in prolonged skin contact.

The enzymatic activity of fecal matter sharply raises skin surface pH, stripping the acid mantle and triggering an inflammatory response. Consistent nappy changes, appropriate absorbent capacity, and barrier creams together are solutions to this cycle. When any one element is compromised, either frequency of change or material quality, dermatitis rates climb demonstrably.

For adolescent and adult women, an equivalent vulnerability exists during menstruation. Extended contact with saturated absorbent materials elevates local moisture and pH, producing an environment conducive to bacterial vaginosis and vulvar dermatitis. Clinical guidance consistently recommends regular pad or tampon changes irrespective of flow volume, the interval matters as much as saturation levels.

Infection Pathways That Begin with Hygiene Gaps

As per the systematic review by Bowen et al. (2015) in PLOS ONE, over 162 million children in low- and low-middle-income countries are affected by impetigo at any given time, with most cases occurring in tropical, resource-limited regions. These figures underline how everyday hygiene practices influence skin health and help prevent infections from spreading.

Urinary tract infections in women and girls are closely linked to perineal hygiene. The urethra’s proximity to the rectum makes it easy for faecal bacteria, particularly Escherichia coli, to spread if cleaning is inadequate. Changing underwear regularly, wiping front to back, and using breathable fabrics can help reduce this risk.

Fungal infections require particular attention in warm, humid climates, where heat and moisture create ideal conditions for dermatophytes to thrive and persist. As per Gupta, Chaudhry, and Elewski (2003) in Dermatologic Clinics, tinea corporis, tinea cruris, and other superficial dermatophytoses show increased prevalence in developing and tropical countries due to elevated temperatures and sustained humidity, which create an environment conducive to fungal proliferation.

India's combination of heat, humidity, and fabric choices creates a near-constant conducive environment for dermatophyte infections like tinea cruris (groin ringworm). These infections respond well to antifungal treatment but return when underlying hygiene practices are not followed appropriately. Dry skin after bathing, moisture-wicking undergarments, and clean, well-ventilated footwear are among the most evidence-backed preventive measures available.

Hence for females, during periods, it's important to have a sanitary napkin or period panty which has rash free and leakage prevention capabilities.

Long-Term Consequences Beyond the Skin

Hygiene practices for adults, including the use of well-fitted absorbent products, have consequences that extend beyond comfort. Improper or prolonged use of adult diapers can create conditions for recurrent urinary tract infections (UTIs).

Hygiene-related infections place a heavy burden on public health. In India, poor menstrual hygiene is linked to school absenteeism, reproductive tract infections, and delays in seeking care because of stigma. Outcomes are shaped by access to products, awareness, and their quality.

Hygiene Access as a Health Equity Issue

Clinical recommendations are only actionable where products and information reach people reliably. In rural and peri-urban India, access to affordable, functional hygiene products such as absorbent sanitary pads, quick dry & reliable baby / adult diapers, and effective skin-cleansing agents remains uneven. Affordability and quality often sit at opposite ends of the market.

When hygiene products fail in absorbency, breathability, or durability, the burden falls on the user's skin and health. A diaper that leaks prematurely does not reduce dermatitis risk; a sanitary pad which leaks fails mid-cycle, does not support menstrual hygiene management. Product performance, therefore, is inseparable from health outcomes.

Practice Over Knowledge

The evidence base for hygiene as preventive medicine is extensive and long-established. The gap that persists is between knowledge and consistent practice, sustained by habit formation, reliable access to appropriate products, and normalisation of conversations around intimate health.

Maintaining daily hygiene by using the right products and following regular routines decreases the risk of infections, protects the skin, and promotes overall long-term health.

By Vijay Chaudhary, Founder of Lakons. The Healthandme team was not involved in authoring this story