Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

Vanessa Trump, , the former wife of Donald Trump Jr., has revealed that she has been diagnosed with breast cancer and recently underwent a medical procedure as she begins treatment and recovery.

In a post on social media platform Instagram, Vanessa informed of recently undergoing a medical procedure as she begins treatment and recovery. However, she did not disclose additional details about the stage of the cancer or specifics of her treatment plan.

"I’ve recently been diagnosed with breast cancer," Vanessa wrote in the post. "While this isn’t news anyone expects, I’m working closely with my medical team on a treatment plan."

She also revealed that doctors performed "a procedure earlier this week" and thanked her family, children and medical team for supporting her through the diagnosis and recovery process.

"I am staying focused and hopeful while surrounded by the love and support of my family, my kids, and those closest to me," she added.

The announcement also drew support from members of the Trump family and supporters online, including a public response from Ivanka Trump, who commented: "Praying for your continued strength and a swift recovery. Love you mama."

The post was also liked by Tiffany Trump and rapidly gained engagement as readers reacted to Vanessa’s news.

Vanessa thanked her supporters “for their kindness” and also requested for privacy in her road to recovery.

"Thank you for your kindness and support it truly means more than I can express," she wrote. "I kindly ask for privacy as I focus on my health and recovery."

Vanessa was married to Donald Trump Jr. from 2005 until their divorce was finalized in 2018. They share five children together. In 2025, she began a highly publicized relationship with professional golfer Tiger Woods.

Also read: Breast Cancer To Reach Over 3.5 Mn By 2050, Deaths To Surge 44% Predicts Lancet Study

What Is Breast Cancer?

Breast Cancer occurs when abnormal cells in the breast grow uncontrollably, often beginning in the milk ducts or lobules. It remains the most commonly diagnosed cancer among women worldwide.

A recent study published in The Lancet Oncology projected that global breast cancer cases could rise to more than 3.5 million annually by 2050.

Major Lifestyle Risk Factors

In 2023, 28 percent of the global breast cancer burden (6.8 million years of healthy life lost to disability, illness, and early death) was linked to six potentially modifiable risk factors. These include:

• High red meat consumption
• Tobacco use and second-hand smoke exposure
• High blood sugar levels
• High body mass index (BMI)
• Excessive alcohol use
• Low physical activity

Read More:Olivia Munn Opens Up About Detecting No-Symptom Breast Cancer With Lifetime Risk Assessment Test

Regular checkups are the cornerstone of early breast cancer detection. According to the World Health Organization (WHO), early identification of breast abnormalities greatly increases the chances of effective treatment and survival. Women who ignore screenings may face delayed diagnosis, which can complicate treatment.

• Schedule regular mammograms and clinical breast exams
• Perform monthly self-examinations
• Know your family medical history
• Maintain a healthy weight and active lifestyle
• Pay attention to hormonal health
• Watch for physical changes such as persistent pain, swelling, or skin dimpling.

Many couples who consult a fertility specialist are advised to undergo Assisted Reproductive Techniques, such as in vitro fertilisation (IVF). However, there are many myths linked to IVF regarding pain and injections. According to the experts, the procedure is more manageable and less painful than commonly believed. This article helps debunk myths surrounding IVF injections.

Dr. Sneha Sathe, Clinical Director & Fertility Specialist, Nova IVF Fertility, Chembur, Mumbai and Dr. Anuranjita Pallavi, Consultant- Fertility & IVF Specialist, Motherhood Fertility & IVF , Kharghar, Navi Mumbai collectively listed some of the most common myths associated with the stigma surrounding IVF – whether it is painful, complicated, or even worth the financial investment.

Currently, many are opting for IVF, a process where eggs are collected from a woman’s ovaries and fertilised with sperm in a laboratory. The embryo is then transferred into the uterus for conception. Couples may consider IVF for several reasons, such as blocked fallopian tubes, low sperm count, hormonal issues, age-related fertility decline, or unexplained infertility. For many, IVF becomes a go-to option, offering hope and a chance to start a family. However, despite its growing success, IVF is still surrounded by fear, especially when it comes to injections and pain. Social media, hearsay, and lack of awareness often make the process seem more difficult and can prevent couples from exploring it.

The IVF journey is different for each woman. IVF does involve medical procedures, but it is not as painful or overwhelming as people believe. One of the biggest concerns around IVF is the use of injections. These injections are given to stimulate the ovaries to produce multiple eggs. While the idea of daily injections can be intimidating, most are administered using very fine needles and are relatively painless. Patients may feel slight discomfort, similar to a small prick, but it is usually manageable and short-lived.

Common IVF Myths Debunked

1. Myth: IVF injections cause extreme pain—IVF injections cause minimal discomfort, and women should not worry. Most patients experience mild and easy-to-manage pain, especially with guidance from an expert.
2. Myth: IVF is a very complicated and stressful process. While IVF consists of multiple steps, doctors guide patients throughout the journey. With proper counselling and support, the process becomes much smoother and less stressful for women.
3. Myth: IVF guarantees pregnancy in one cycle - IVF increases the chances of pregnancy but may not be successful on the first attempt. Success depends on factors such as age, health, and underlying fertility conditions. So, do not get disheartened if the first cycle fails. The first cycle provides a lot of information, and certain steps can be taken, along with changes made to the next attempt, in order to improve the chances of success.

Understanding the facts and debunking common myths can help reduce anxiety and build confidence in couples.

Couples often hesitate to opt for IVF due to the fear of injections and the assumption that the process will be extremely painful or emotionally exhausting. However, with advancements in fertility care today, IVF has become far more patient-friendly, safe, and comfortable than most people imagine. One of the biggest myths is that IVF injections are administered painfully multiple times throughout the day. In reality, most injections are scheduled and simple to administer, and many couples are even taught how to take them comfortably at home.

Another important aspect people often overlook is that IVF treatment today is highly personalised.

While some women may experience temporary bloating, mild cramps, mood changes, or fatigue due to hormonal medications, these symptoms are usually manageable and closely monitored by the facility team. Most women can continue their daily routine during treatment without any major challenges. Equally important are support, counselling, and clear communication with the fertility team, which help reduce anxiety and build confidence. It is necessary to understand that IVF is a step-by-step guided process designed to give couples hope and a better chance at parenthood. Hence, make sure to consult an expert, clear all doubts, and initiate IVF treatment as soon as possible to achieve the dream of pregnancy.

Everyone knows that when cancer is detected early, cure rates are far superior, side effects are much less, and treatment expenses are also less.

Diagnosis of cancer depends upon carrying out various tests and then their analysis to reach a conclusion.

How AI Supports Cancer Diagnosis

These tests are radiological, like Chest X-ray, CT scans, MRI, Mammography, etc., and in histopathology, analysis of tissue, be it a small biopsy, large specimen handling, or Frozen Section. AI is empowered with large data to suggest and analyze minute patterns that are difficult for a human mind to comprehend, supported by machine learning.

With the use of AI in the analysis of radiological data, it points out suspicious changes (data is fed into its memory), but they are not very clearly visible to the human eye. Hence, it alerts the radiologist to have a close look at that and enhances accuracy and reduces the chances. It is the radiologist who takes the final call because it has to be correlated with the patient’s clinical findings and other information from other investigations of the patient.

Early detection of breast cancer has received a big boost from the integration of AI in the analysis of mammography data. Similar applications are also used by pathologists when they are examining the tissues because the final diagnosis of cancer can be obtained on histopathology only.

Challenges In The Use Of AI

Use of AI is not without challenges: knowledge of proper tools and applications is critical. Results can not be relied upon blindly, and an expert is very critical of their analysis. Sometimes there may be an improper result that needs to be filtered out.

It's time to accept that AI is present and not the future, and we need to learn, adapt, and use it to the benefit of mankind. India is making great strides in AI, and many startups have also come up that are doing a great job.

The real strength of AI in the care of cancer mainly lies in its ability to support the doctors in making faster, sharper, and more well-informed decisions. It can also reduce delay in diagnostics, improve efficiency of screening, and help in detecting cancers at a stage where outcomes of treatment are much better.