Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

Receiving a cancer diagnosis is scary, but what often causes greater harm is the delay in finding the disease and starting treatment. Many patients visit doctors only when symptoms become too obvious to ignore, by which time the illness has already advanced and is far harder to control. In most cases, cancer is caught late not because it hides well, but because people skip routine screenings.

In an Instagram video shared on November 6, Dr Jayesh Sharma, consultant surgical oncologist at ITSA Hospitals, spoke about four key tests that can help detect cancer early and reduce the number of late-stage cases.

4 Tests That Help Catch Cancer Early

Dr Sharma explained that there are four screenings everyone should consider. He noted that these tests can help identify cancer at the very first stage, when abnormal cells have formed but have not yet begun to spread. Detecting it at this point allows doctors to remove the cells completely, giving patients an excellent chance of recovery.

Mammography

Dr Sharma advised getting a mammogram once around the age of 40. He mentioned that while yearly tests are often suggested, most people do well with a screening every two years.

Cervical Cancer Screening

Cervical cancer remains one of the most common cancers in women. According to Dr Sharma, the Pap smear is a reliable way to catch early changes in cervical cells, even before symptoms appear.

Stool Test

He also recommended a stool test as a simple way to look for signs of stomach cancer. The earliest sign of trouble in the stomach is often hidden bleeding, which can be picked up through this test.

Chest CT Scan

For people who have been heavy smokers over many years, Dr Sharma suggested a chest CT scan. This group faces a higher chance of lung cancer, and a scan can help identify changes in the lungs at an early stage.

Symptoms Of Cancer

Warning signs of cancer can appear in many ways, and the symptoms usually depend on which part of the body is involved.

Some broad symptoms that may point to cancer, though they can occur in many other conditions as well, as per Mayo Clinic include:

• Fatigue that does not improve
• A lump or thickened area you can feel beneath the skin
• Unexpected weight loss or gain
• Changes in the skin, such as darkening, redness, yellowing, slow-healing sores, or new changes in moles
• Altered bowel or bladder habits
• A cough that lingers or ongoing breathing trouble
• Difficulty swallowing food
• A rough or hoarse voice
• Regular indigestion or discomfort after meals
• Ongoing, unexplained joint or muscle pain
• Recurring fevers or night sweats without a clear cause
• Bleeding or bruising without explanation

When To Seek Medical Advice

You should contact your doctor if any symptom continues for a long time or gives you reason to worry.

If you feel fine but are anxious about your cancer risk, speak with your doctor about it. They can guide you on the screening tests or checks that may be suitable for you

Recent data from the Human Fertilisation and Embryology Authority show a sharp rise in the number of women opting for egg-freezing. Yet the subject remains clouded by many misunderstandings. The decision itself is not simple. It involves emotional questions, significant costs and the physical demands of treatment. One common misunderstanding is the belief that egg freezing can harm egg quality, when the procedure does not lower the inherent quality of the eggs you already have.

We got in touch with Dr Shaweez Faizi, Fertility Specialist, Nova IVF Fertility, Mangalore, who told us more about the same.

What Is Egg Freezing?

Egg freezing, also called oocyte cryopreservation, is a fertility option in which a woman’s eggs are collected, frozen, and kept for future use. The steps include taking hormones to help the ovaries produce multiple mature eggs, retrieving those eggs through a short clinical procedure, and freezing them through a rapid cooling method known as vitrification.

As per Healthline, the frozen eggs are then stored in liquid nitrogen. When pregnancy is planned later, the eggs are thawed, fertilized in a laboratory, and the embryo is transferred to the uterus.

How Egg-Freezing Works?

The journey begins with roughly 8 to 12 days of hormonal tablets and injections that help several follicles grow at once. Dr Shaweez Faizi told us that doctors then use an ultrasound-guided needle to retrieve the mature eggs under light anaesthesia. The eggs are preserved through vitrification. The medication does not pull eggs from future years. It acts only on that month’s cohort, which is why medical bodies consider the procedure safe and ethically sound.

Can Egg Freezing Lower Your Egg Quantity?

Dr Shaweez Faizi told us that egg-freezing does not drain your ovarian reserve for life. The process collects only the group of eggs that your body was already preparing to release in that month. Some women notice a short-term dip in AMH after the procedure, but this usually settles with time. The stored supply inside the ovaries remains unchanged.

For those unversed, AMH, or Anti-Müllerian Hormone, is commonly used to assess ovarian reserve, meaning the approximate number of eggs still present in a woman’s ovaries.

Anti-Müllerian Hormone and Reserve

AMH is often treated as a marker of ovarian reserve, though it naturally varies. Studies show that a small number of women experience a temporary fall in AMH after stimulation, followed by a return to baseline. Specialists usually advise repeating the AMH test a few months after retrieval to get an accurate picture.

Egg Freezing Success Rates

Age at the time of freezing and the number of eggs stored have the strongest influence on outcomes. Global data suggest that women under 38 who freeze about 20 eggs tend to have higher chances of a future live birth. Older women usually retrieve fewer eggs per cycle, and success rates decline. Indian clinics report a wide range of live-birth outcomes, depending on age and the number of usable eggs.

People with low AMH or diminished reserve will have fewer eggs from the start. The issue lies in the baseline biology, not in the freezing itself. Those who have had ovarian surgery, such as endometrioma removal, may have reduced reserve due to the operation and should plan their timing carefully.

Women facing chemotherapy or serious medical treatment should consult both oncologists and fertility specialists. The Indian Fertility Society recently issued guidance on handling low ovarian response and preservation choices.

Practical Steps For Those Considering Egg Freezing

Dr Shaweez Faizi shared a few practical steps for women considering egg freezing:

• Start with basic tests such as AMH, AFC and a hormonal panel.

• Ask detailed questions about expected egg yield for your age, the number of cycles you may need, and the clinic’s real success figures. Advertising often paints a brighter picture than the data.

• Plan financially for medication, scans, retrieval, freezing and long-term storage.

• Keep age in mind, as younger eggs are more likely to develop into healthy embryos.

• Choose established centres that follow national and international practice standards.

Egg-freezing is a recognised and safe method to preserve fertility options, but it is not a guaranteed path to pregnancy.

Costs, success rates and the number of cycles needed vary widely. As the service becomes more accessible in India’s metropolitan centres, careful counselling and realistic planning remain essential before you decide.

India’s growing dependence on quick, over-the-counter remedies has drawn fresh concern from a senior orthopaedic and sports surgeon in New Delhi. In a recent Instagram video, Dr Obaidur Rahman of Dr Ram Manohar Lohia Hospital warned that the country’s casual use of a common antibiotic is undermining its effectiveness and pushing India closer to a major public health challenge. His message, shared through a post and video, called attention to an urgent issue that often goes unnoticed in everyday medical choices.

What Is Azithromycin?

Azithromycin, sold under brand names such as Zithromax, Azee and Zmax, is a macrolide antibiotic prescribed for various bacterial infections. It works by slowing the growth of harmful bacteria. It does not help with viral illnesses like the common cold or flu, according to MedlinePlus.

Azithromycin Is Being Used “More Than Toffee or Roti”

Dr Rahman explained that one particular antibiotic has become so familiar in Indian homes that many people take it without a second thought. He noted that families frequently reach for this medicine to treat colds, coughs and mild fevers, despite the fact that most of these illnesses are viral. Because antibiotics do not work on viruses, this habit has increased unnecessary exposure and created ideal conditions for resistance to form.

In his post, he described the extent of the overuse by saying that the tablet is consumed even more commonly than basic household foods. This pattern, he said, has quietly pushed India into a vulnerable zone.

Azithromycin Antibiotic Resistance: Azithromycin Losing Power Against Key Bacteria

The antibiotic at the center of his warning is Azithromycin, a drug often prescribed for sore throats and upper respiratory tract infections. Dr Rahman noted that it was once effective against Mycoplasma Pneumonia, a bacterium responsible for pneumonia in adults and children.

He pointed out that this is no longer the case. According to him, India now shows an alarming 80 to 90 percent resistance to Azithromycin when treating infections caused by this bacterium. A medicine that once addressed a wide range of respiratory problems is no longer reliable for many patients.

Azithromycin: Antibiotic Resistance Already Reaching Clinics

Dr Rahman said that antibiotic resistance is not an abstract idea but something he encounters in his orthopaedic practice. He has seen cases where routine antibiotics fail entirely, leaving patients with few options. When commonly used drugs stop working, he added, treatment becomes more complicated, more expensive, and sometimes impossible.

His concern is that if such misuse continues unchecked, India could face a situation where even simple infections become difficult to manage.

The surgeon urged people to avoid taking antibiotics without proper medical advice. Most seasonal respiratory infections resolve on their own, and unnecessary drugs only add to the resistance problem. He encouraged viewers to share the information, especially with those who often purchase antibiotics over the counter.

Azithromycin Warning: Why This Warning Matters Now

Dr Rahman, who works at PGIMER and RML Hospital and specialises in bone, joint and sports injury care, said his experience treating a large volume of patients has made the issue impossible to ignore. He believes that without immediate changes in how antibiotics are used, India risks losing access to medicines that save lives in emergencies.

His message acts as a reminder that antibiotic resistance does not appear suddenly. It builds slowly through small, routine choices. And, as he warns, the cost of ignoring these early signs may be far greater than most people realise.