Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

The view generally is that the occurrence of knee issues is usually associated with age, injury or overexertion. However, there is another reason people ignore: lack of movement. If a person leads an inactive lifestyle, spending long hours sitting at a desk, working from the couch, watching TV or doing nothing physical, the eventual consequences for the knees might arise.

Knees are created for motion, and motion is essential for keeping the flexibility of a joint. Their effective functioning depends on the health of the muscles surrounding your knee. The less active various leg muscles are, including quadriceps and other counterparts, the weaker they will be. The muscles help stabilize the knee and can relieve it from some of the burdens during daily activities performed by the knees.

Remaining seated for an extended time can also lead to stiffness. When you sit for a while, you may feel uncomfortable or stiff in your knees when you finally stand up. While the occasional instance of stiffness may go away with movement, constant stiffness can impact mobility and cause people to wish to move even less.

Another issue is gaining weight. Living a sedentary lifestyle causes individuals to become heavier, and excess weight puts more stress on the knees. In time, this added pressure will lead to increased wear of the joints and the development of knee pain and other problems in the musculoskeletal system.

The positive aspect with respect to your knees is that you don’t have to put in hours at the gym to keep them safe. Small, steady efforts can easily do the trick. You can choose to walk for five minutes after being seated for a long time, stretch regularly, take stairs if you are physically able and do some simple workouts for the legs and thighs to increase strength. Low-impact sports such as swimming, cycling and walking can help you maintain muscle power and flexible joints while avoiding the stress on your knees resulting from extensive workouts.

Persistent pain in the knee, however, cannot be treated as a usual symptom of ageing. Knee swelling or prolonged stiffness, difficulties climbing stairs, instability, or pain that has an impact on routine activities should be addressed by health professionals.

Movement is necessary for knees to be strong and flexible. Therefore, if you want your knees to be strong, you need to use them consistently and perform all activities without remaining still for long.

(By Dr Sujoy Bhattacharjee, Chairman & Chief, Max Institute of Robotic Joint Replacement, Max Super Speciality Hospital, Saket)

Blocked ears are one of the most common and irritating problems associated with air travel.

While the sensation usually resolves on its own shortly after landing, for 22-year-old Aida Burkins from California, it persisted and eventually led to a frightening diagnosis of rare head and neck cancer.

Blocked Ears Persisted After Flight

Burkins was travelling to Chicago in May 2025 when her ears became blocked. When she returned home, her ears still hadn’t popped.

She later developed unusual symptoms, including hearing loss and bleeding from her throat.

“I started bleeding into my throat, which would only come out of my nose if I was bent at the hip at about 90 degrees,” the 22-year-old told Newsweek. “My hearing got worse and worse. Then I started getting more tired and losing weight.”

Symptoms Were Initially Dismissed

When Burkins sought medical help, her condition was initially dismissed as “just altitude sickness.” After several months, her hearing had deteriorated significantly.

“Everything sounded so muffled, and I had a ringing that wouldn’t go away,” she said.

Burkins eventually saw an ear, nose, and throat (ENT) specialist, who discovered a mass and noted that her adenoids — soft tissue in the throat, just behind the nose — were inflamed.

“The doctor told me he had never seen anything quite like what I had going on. He couldn’t be sure it was cancer, but he said it was very suspicious,” she told the outlet.

Diagnosed With Rare Head And Neck Cancer

In February 2026, after undergoing CT scans and two biopsies, Burkins learned that she had a widespread tumour affecting the cervical lymph nodes near the base of her skull.

She was diagnosed with nasopharyngeal carcinoma, a rare type of head and neck cancer that starts in the upper part of the throat behind the nose and near the base of the skull, according to the American Cancer Society.

“Hearing I have cancer, all I thought about was not being able to see my babies grow up or do the things they want to do in life. It was horrifying,” Burkins, who is a mother to a 1-year-old and 3-year-old.

Burkins has since undergone months of chemotherapy and radiation. She is now finishing her treatment and hopes to be cancer-free soon as her body is responding well to the treatments.

What Is Nasopharyngeal Carcinoma?

According to the Mayo Clinic, nasopharyngeal carcinoma is a cancer that starts as a growth of cells in the nasopharynx, the upper part of the throat located behind the nose.

The cancer is rare in the United States and occurs much more often in other parts of the world, particularly Southeast Asia.

Nasopharyngeal carcinoma can be difficult to detect early because the nasopharynx is not easy to examine and there may be no symptoms initially.

Symptoms To Watch For

When symptoms do occur, they present non-classic signs which include:

• A lump in the neck caused by a swollen lymph node
• Nosebleeds
• Bloody saliva
• Double vision
• Ear infections
• Facial numbness
• Headaches
• Hearing loss
• Nasal stuffiness
• Ringing in the ears, known as tinnitus
• Sore throat

How Is It Treated?

Treatment for nasopharyngeal carcinoma usually involves radiation therapy, chemotherapy, or a combination of the two, depending on the cancer and the individual patient.

Perimenopause has become a regular conversation and its been high time that people are talking about it. You can see friends discussing it, social media coverage has increased and more importantly women are discussing this with their gynaecologists.

For decades, menopause was thought to be a single event - that is the day the periods stopped, but today we understand that the transition lasts for a few years. These changes can affect the quality of a woman’s life and hence I’m glad the conversation has gained more traction.

Perimenopause-Related Changes

Also read: Yoga Or Strength Training: What Can Help Manage Hot Flashes During Perimenopause?

First lets understand what perimenopause is. It literally means “around menopause” Its a transition phase where the ovaries gradually change the production of the hormones, mainly oestrogen and progesterone. It usually begins in the early 40’s but some women may experience it earlier.

One of the commonest signs of this is a change in the pattern of your menstrual cycle. Periods can be become longer or shorter, heavier or lighter. Basically the menstrual cycle becomes a bit unpredictable.

But periods aren’t the only sign. A woman may start experiencing disturbed sleep cycles. She may wake up randomly at 3am or feel exhausted despite getting 7-8 hours of sleep. Hot flushes and night sweats may also occur. Mood changes, irritability, anxiety and difficulty in concentration can also affect her quality of life.

Some women complain of being forgetful or more commonly used term "experience brain fog”. They forget names, lose train of though or struggle to multitask. There can also be a change in libido, vaginal dryness, discomfort during intercourse, headaches, join pain and alterations in skin and hair.

Besides this there could possibly a change in the body composition. A woman may notice increasing abdominal fat or find difficulty in maintaining her weight even though her lifestyle hasn’t changed.

Why The Current Focus On Wellness Is Important?

Also read: Explained: Why Some Women Start Experiencing Joint Pain As They Approach Menopause

The good part of this increase in awareness is that women are paying more attention to their health early rather than waiting of menopause. This transition phase provides a golden opportunity to reassess exercise, nutrition, sleep and preventative healthcare.

Strength training becomes even more valuable as it helps maintain muscle and bone mass.

Adequate protein, calcium and Vitamin D intake along with a balanced diet helps long term metabolic and bone health.

During this time, its important for a woman to even assess her cardiovascular health. Blood pressure, cholesterol, blood sugar and weight don’t just become numbers on the chart anymore, they become important markers of future health during this time.

Not Every Symptom Should Be Blamed On Hormones

However every label shouldn’t be blamed on perimenopause. Thyroid disorders, anaemia, vitamin deficiencies, depression and few other medical conditions can produce similar symptoms.

Unusually heavy bleeding, bleeding between periods or after intercourse also warrants medical assessment rather than being dismissed as “just hormones”.