Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

Amid reports of the hantavirus outbreak onboard the cruise ship MV Hondius, and two Indian crew members, India’s Ministry of Health and Family Welfare has stepped up surveillance measures.

While the Indian Embassy in Spain has confirmed that the two Indian nationals are currently asymptomatic and are being evacuated to the Netherlands for quarantine, health authorities in the country are closely monitoring the situation in coordination with national and international health agencies.

Notably, the Indian Council of Medical Research (ICMR) has mobilized its formidable "Viral Shield", a sophisticated network of 165 specialized laboratories, called the Virus Research & Diagnostic Laboratory (VRDL), to ensure that the rat-borne virus does not breach the country's borders.

What Are The VRDLs?

The 165 laboratories include

• 11 Regional level,
• 27 State level
• 127 medical college level,
• It covers 31 States and Union Territories of India and functions under the umbrella of the Department of Health Research (DHR)/ ICMR.

Post-pandemic, VRDLs are actively engaged in integrated surveillance for Influenza-like Illness (ILI) and Severe Acute Respiratory Infection (SARI), monitoring for pathogens like Influenza A/B, Mycoplasma pneumonia, and SARS-CoV-2 variants.

In 2025, Union Minister of State for Health and Family Welfare, Anupriya Patel, said, VRDL has stood as “sentinels in protecting the country”.

She added that 16 VRDLs are now equipped with Bio-Safety Level-3 (BSL-3) facilities for studying high-risk pathogens, playing a central role in detecting outbreaks of Nipah, Zika, and Kyasanur Forest Disease.

Also read: Hantavirus: Is Climate Change Behind The Outbreak?

What's The Status Of MV Hondius Passengers?

Amid stiff opposition from the locals, the Dutch-flagged vessel MV Hondius, carrying 94 people, including Filipinos, Britons, Americans, Indians, and Spaniards, arrived in Spain's Canary Islands on May 10. All have been evacuated and repatriated.

Two of the 17 American passengers evacuated from the hantavirus-hit MV Hondius have tested positive, the US Department of Health and Human Services (HHS) announced today.

A French woman onboard the same cruise has also tested positive for hantavirus, and her health worsened in the hospital overnight, French Health Minister Stephanie Rist said.

The woman was among five French passengers repatriated from the MV Hondius.

"It’s not surprising that others on the ship will test positive for hantavirus in the coming days. What’s crucial is that they don’t pass this on to others- those most at risk: who they live with/family/friends as they head home. Quarantine for next 45 days super important," Prof. Devi Sridhar, Professor & Chair of Global Public Health, Edinburgh University, said in a post on the social media platform X.

WHO Guidelines On Hantavirus

Read More: Why The Norovirus Outbreak On A Caribbean Cruise Ship Is Not A Cause for Panic

The WHO maintains that the eight passengers on board have been infected with hantavirus. While three have died, six have been hantavirus infection has been confirmed in six cases.

Dr. Maria Van Kerkhove, the WHO’s head of epidemic and pandemic preparedness, said that after being brought to shore, passengers will be kept cordoned off from the public and taken to repatriation flights.

In their home countries, many will be taken onward to isolation facilities. Van Kerkhove said that the WHO is recommending “active monitoring and follow-up” for all passengers and crew for 42 days from their “last point of exposure” to a confirmed case.

"Our recommendation is daily health checks, at home or in a specialized facility. It's up to countries to develop their policies, but our recommendations are very clear," Van Kerkhove said, highlighting that the incubation period for the virus was up to six weeks.

In my journey as a neonatologist, one truth has remained constant—no healthcare system can succeed without strong nursing care. We often celebrate breakthroughs in technology and clinical expertise, but at the bedside, where outcomes are truly shaped, it is the nurse who makes the difference.

Nowhere is this more evident than in the Neonatal Intensive Care Unit (NICU), a space I have spent decades working in. Caring for extremely premature babies—sometimes born as early as 24–26 weeks—requires far more than advanced machines or protocols. These fragile lives demand minute-to-minute monitoring, swift clinical judgment, and unwavering attention.

It is the nurse who notices the subtle drop in oxygen levels, the slight change in skin tone, or the early signs of infection. Many times, it is their timely intervention that prevents a complication from becoming a crisis. I have witnessed countless such moments—quiet, uncelebrated, yet life-saving.

What we see in practice is strongly supported by global data. Research has consistently shown that for every additional patient assigned to a nurse, the risk of patient mortality increases by nearly 7%. Hospitals with optimal nurse-to-patient ratios report lower infection rates, shorter hospital stays, and significantly better survival outcomes. These are not marginal gains—they are decisive factors in patient care.

And yet, as healthcare advances, a critical gap is becoming increasingly visible.

Over the past five to six decades, medicine has transformed dramatically. We have moved from general practice to highly specialized and super-specialized care—interventional cardiology, robotic surgeries, advanced oncology, and neonatal care that can support extremely preterm infants. These advancements have contributed to a remarkable rise in life expectancy in India—from around 41 years in the 1960s to over 69 years today.

But while medicine has rapidly specialized, nursing training has not evolved at the same pace. This imbalance is one of the most pressing challenges in healthcare today.

The Global Shortage For Nurses

India, like many parts of the world, faces a significant workforce gap. The World Health Organization estimates a global shortage of nearly 6 million nurses. While we continue to train and recruit more nurses, the real challenge lies in specialized skill development. In many hospitals, nurses are assigned to departments based on immediate needs rather than structured career pathways. They learn on the job, often in high-pressure environments, building expertise through experience.

While this speaks volumes about their dedication and resilience, it also highlights a systemic limitation. Specialized medicine cannot function optimally without specialized nursing.

In a NICU, for instance, managing non-invasive ventilation, performing neonatal resuscitation, ensuring strict infection control, and counselling anxious parents are not basic skills—they are specialized competencies. These require structured training, repeated practice, and continuous upskilling.

Bridging The Gap: Training Initiatives In Practice

Recognizing this gap, we recently conducted 10 focused workshops across Karnataka as part of the State Neonatal Nurses Conference. These workshops were designed to strengthen critical skills such as the Neonatal Resuscitation Program (NRP), Non-Invasive Ventilation (NIV), and effective communication within the NICU. What stood out was the response.

Participation exceeded capacity by nearly four times. Nurses travelled long distances, eager to learn, engage, and enhance their skills. This was not just enthusiasm—it was intent. It was a clear indication that nurses are ready to grow, to specialize, and to deliver better outcomes. What they need is access—structured, scalable, and sustained opportunities to learn.

Globally, the impact of investing in nursing education is well documented. Hospitals with a higher proportion of well-trained nurses have reported up to 20% lower mortality rates in certain patient groups. Healthcare systems that prioritize continuous professional development for nurses consistently demonstrate better patient safety outcomes and higher satisfaction levels.

The Need for Systemic Change in Nursing Education

India has begun to take steps in this direction. Initiatives such as the Neonatal Nurse Fellowship introduced by the National Neonatology Forum are important milestones. However, these programs, while valuable, are not accessible to all. Financial constraints, time commitments, and geographical limitations often restrict participation.

This calls for a shift in approach.

Training must move beyond select programs and become an integral part of the healthcare system. We need modular learning formats, simulation-based training, in-hospital skill development programs, and digital platforms that allow continuous learning. Every nurse—irrespective of location or institution—should have access to opportunities that help them grow.

Because ultimately, no matter how advanced our systems become, outcomes depend on the people delivering care.

I often remind my teams of a simple reality—without strong nursing care, the success of any medical speciality is less than 50%.

Beyond systems, statistics, and strategy lies the human side of nursing—a dimension that cannot be measured but is deeply felt.

In the NICU, nurses are not just caregivers to fragile newborns; they are also a source of strength for parents navigating uncertainty and fear. I have seen nurses hold the hands of anxious mothers, explain complex medical situations with patience, and provide reassurance during some of the most difficult moments a family can experience. They are the bridge between clinical excellence and emotional care.

And yet, despite their central role, nurses often remain under-recognized and under-supported. If we are serious about strengthening healthcare, this must change.

Empowering nurses is not just about improving skills—it is about acknowledging their value, creating structured career pathways, and ensuring they are included in decision-making processes. It is about building a culture of respect, where nursing is seen not as support, but as a critical pillar of care delivery.

The future of healthcare will not be defined by technology alone. It will be defined by the strength, capability, and empowerment of its workforce.

And at the heart of that workforce are our nurses. If we want safer hospitals, better clinical outcomes, and resilient healthcare systems, the path forward is clear—we must invest in our nurses, not just in numbers, but in their growth, training, and empowerment. Because in every critical moment I have witnessed, one truth stands out—quietly, consistently, and powerfully: Empowered nurses don’t just support care. Empowered nurses save lives.

Dr. R. Kishore Kumar is President – National Neonatology Forum, Karnataka Chapter

Post-viral syndromes are a classic example of the body not feeling better even after the viraemia is over. When a viral infection ends, most people expect life to quickly return to normal.

For many, it does, but for some, recovery stretches on for weeks or even months. This condition, often called a post-viral syndrome, is now being seen more clearly across the country, especially after the COVID-19 pandemic. Thus, the main question that arises is why doesn’t recovery end when the infection is gone? The answer is that the body does not always ‘reset’ immediately.

Why Symptoms Continue After the Infection Clears?

During an infection, the body’s defense system becomes highly active to fight the virus. In some people, this response does not completely settle down even after the virus has been cleared. This can lead to ongoing tiredness, body aches, or a general feeling of being unwell. This could be due to the immune system remaining partially activated.

In certain cases, the body’s defense system may even start reacting in an unbalanced way, affecting normal tissues. This is why some people develop symptoms like joint pains, palpitations, or dizziness after a viral illness, even though tests may not show an active infection.

Another important reason is energy depletion. Viral infections can temporarily affect how the body produces and uses energy. As a result, even small physical or mental efforts can feel exhausting. Many patients describe a pattern where they feel better, try to return to normal activity, and then feel worse again. This cycle can delay full recovery. The nervous system can also be affected. Some people experience what is commonly called ‘brain fog’, poor sleep, or a sense of imbalance in heart rate and blood pressure. These symptoms are real and are part of the body’s recovery process.

POTS Syndrome

Also, there is something called POT (Positional Orthostatic Tachycardia) syndrome. Patients, when they get up and stand, develop mild giddiness and palpitations.

It is also important to understand that the body may take time to rebuild strength. Muscle loss, physical inactivity, and lack of appetite are common effects following an illness.

Why Recovery Should Not Be Rushed

Consequently, when an individual has recovered from the virus, it is more than just getting rid of the virus. It involves restoring and getting stronger over time. Most importantly, recovery should never be rushed. Pushing too hard or returning to high levels of activity too soon after becoming ill can lead to worsening of symptoms and therefore prolong the recovery time.

A more effective way to recover is by taking a gradual, steady approach. Recovery involves resting adequately, maintaining a nutritious diet, engaging in light exercise and receiving adequate amounts of sleep and at the same time being aware of how your body feels. Long-term symptoms are not in your head. They are part of the process of healing that occurs after some forms of infection.

Most people will recover, but patience and using proper methods are key to recovering completely. It is also important to understand that recovery involves rebuilding the strength that the body needs time to restore this balance.

It is important not to get carried away assuming post-viral syndrome, but consult a physician and not miss out on an underlying medical disorder, and investigate appropriately.