Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

A blood test is considered the first step towards fertility enquiries, but for many, the results might seem like a confusing jumble of numbers and acronyms. Reports sometimes contain terms like AMH, FSH, LH, AFC, and estradiol, which makes patients confused if a single "abnormal" figure indicates they are unable to conceive.

The truth is more reassuring, and more nuanced. Fertility experts stress that a person's fertility cannot be ascertained by a single test. Instead, these markers serve as parts of a bigger picture, assisting fertility specialists in comprehending reproductive health and suggesting the best course of action when necessary.

Fertility Tests Are Guides, Not Verdicts

The idea that a single blood test can determine whether a woman would naturally become pregnant is one of the most widespread myths. Age, egg quality, ovulation, sperm health, uterine health, lifestyle, and underlying medical issues are some of the factors that actually affect fertility.

Although diagnostic markers offer useful information, they must always be interpreted in conjunction with the couple's overall reproductive profile, clinical history, and ultrasound results.

Also read: How Menopause Changes Heart Health Risks?

Understanding The Ovarian Reserve “AMH”

Many women with low AMH can still achieve successful pregnancies, especially if they continue to ovulate regularly. Similarly, women with high AMH are not necessarily more fertile, elevated AMH levels in women also means Polycystic Ovary Syndrome (PCOS), where ovulation may actually be irregular. For fertility specialists, AMH is useful in predicting the number of eggs that are likely to respond to ovarian stimulation medication, based on which they customize IVF treatment.

Also read: Making IVF Affordable: Experts Push For Insurance Cover, Public Funding & Better Access To Fertility Care In India

FSH Determines Ovarian Function

Our pituitary gland produces Follicle Stimulating Hormone (FSH) and this hormone helps in stimulating egg development.

Usually, the second or third day of the menstrual cycle is when FSH is measured. If ovarian reserve is reduced, that is higher-than-normal levels, which may imply that ovaries need more stimulation to mature eggs. From cycle to cycle the FSH levels change.

Also read: NCR's Long Commutes Are Stealing Sleep & Affecting Reproductive Health

LH And The Ovulation Story

FSH and luteinizing hormone (LH) cooperate to control ovulation. The ovary releases a developed egg in response to an increase in LH.

LH levels may be disproportionately greater than FSH in PCOS-affected individuals, which can lead to irregular menstrual periods and ovulation. Instead of using LH alone, fertility specialists assess it in link with other hormone markers.

Also read: World Embryologist Day: What Really Happens Inside An IVF Lab?

Estradiol And AFC: Completing The Picture

An indicator of ovarian activity during the menstrual cycle is estradiol (E2), a type of estrogen generated by growing follicles. Combined interpretation is crucial since elevated early-cycle estradiol levels can occasionally conceal an elevated FSH.

The Antral Follicle Count (AFC), which is done via a transvaginal ultrasound, is another crucial evaluation. AFC gives an additional indication of ovarian reserve by counting the number of visible tiny follicles in the ovaries.

Indeed, the combination of AMH and AFC provides a more thorough insight than any test by itself.

Also read: World IVF Day: Why Men Need To Be Part Of The Fertility Conversation

Fertility Evaluation Isn't Just For Women

Female hormone testing frequently receives greater attention, whereas male fertility contributes to roughly half of all infertility issues.

A semen screening remains one of the most significant and cost-effective tests, measuring sperm count, mobility, and morphology. When necessary, additional hormonal or genetic tests might be suggested.

Era Of Self-Diagnose

After getting a test report, many people search the web for quick answers, but those disguised numbers without proper medical context from a specialist can erupt unnecessary tension.

The fertility markers depend on a variety of factors, some of which include: age, weight, menstrual history, prior pregnancies, medications, hormonal status, and lifestyle.

Therefore, understanding the parameters like “low” or “high” online may create chaos within the individuals. Instead, consult a fertility specialist to decode the report.

By Dr Rubeena Zainab, Senior Consultant - Reproductive Medicine, Milann Fertility and Birthing Hospital, Bengaluru

Period hygiene is something that girls today are more aware of. This is because they have access to a lot of information from schools, doctors, social media and public health campaigns.

People are now more open to talking about periods than they were a years ago. Knowing about period hygiene does not always mean that girls are doing things the right way.

A lot of girls are still not sure how often they should change their sanitary pads or how to keep themselves clean. They also do not know which menstrual product is best for them.

Educating Young Girls About Menstruation

This is where parents can help. They should start teaching girls about menstruation before they get their period. This way girls will know that getting their period is not something to be scared of.

Parents should tell girls to change their sanitary pads every hour even if they are not completely soaked. They should also teach girls to wash themselves with clean water. Using soaps or fragrances is not necessary and can be bad for the skin.

When it is raining and the air is damp girls should keep themselves dry by patting themselves after washing. Wearing cotton underwear that can absorb moisture is also a good idea. This can help prevent infections.

Parents should also talk to girls about how to use menstrual products safely. Whether a girl uses sanitary pads, tampons, menstrual cups or period underwear she should know how to use them clean them and replace them correctly. If girls do not use these products the way they can get infections or feel uncomfortable.

Also read: Bryan Johnson's New 2.6M Women's Health Project Centers on Girlfriend's Menstrual Blood

Menstrual Products

There are different menstrual products available today. This is a thing because girls can choose the products that are best for them. Having so many options can also be confusing especially for teenagers.

Instead of saying that one product is better than another we should focus on making sure girls have all the information they need to make good choices.

All menstrual products are safe if used correctly. Girls should feel like they can try products ask for help when they need it and choose the products that make them feel good, about themselves.

By Dr Nishita Shah, Gynaecologist, Saifee Hospital

Medical tourism is no longer just a trend—it's becoming a practical choice for millions of people worldwide. Whether it's traveling abroad for an affordable heart surgery, a dental implant, cosmetic procedures, or fertility treatment, more patients are exploring healthcare beyond their home countries.

But is medical tourism always a good idea? While it can offer significant savings and quicker access to treatment, it also comes with important risks that patients should understand before booking a flight.

What Is Medical Tourism?

Medical tourism refers to traveling to another country to receive medical treatment. People often choose this option because healthcare services may be less expensive, waiting times may be shorter, or certain treatments may not be easily available in their own country.

Popular destinations include countries such as India, Thailand, Turkey, Singapore, Mexico, and South Korea, each offering specialized medical services ranging from orthopedic surgeries to cosmetic procedures.

Benefits Of Medical Tourism

One of the biggest reasons people seek treatment abroad is cost. In many cases, medical procedures can cost significantly less than they would in countries with expensive healthcare systems, without necessarily compromising on quality.

Another major advantage is faster treatment. Patients who face months-long waiting lists for surgeries at home may be able to receive care within days or weeks overseas.

Understanding The Risks

Despite its advantages, medical tourism isn't without challenges.

Healthcare standards, regulations, and infection-control practices vary from country to country. Patients may also face language barriers, making communication with healthcare providers more difficult.

Follow-up care is another important concern. If complications develop after returning home, local doctors may have limited information about the treatment performed abroad, making recovery more complicated.

Long-distance travel soon after surgery can also increase the risk of complications such as blood clots, particularly after major operations.

Additionally, legal protections differ between countries. If something goes wrong during treatment, seeking compensation or resolving medical disputes may be more difficult than in your home country.

Also Read: US Issues Measles Alert After Infected Visitor Spent 11 Hours at Universal Studios Hollywood

How To Stay Safe

Experts recommend researching hospitals carefully before making any decisions. Look for internationally accredited healthcare facilities, experienced specialists, and verified patient reviews.

Patients should also request detailed information about the procedure, possible complications, recovery timelines, and total costs—including unexpected expenses.

Before traveling, discuss your plans with your primary healthcare provider. They can help determine whether traveling for treatment is appropriate and advise you on vaccinations, medications, and post-treatment follow-up.

Finally, purchase travel insurance that specifically covers medical procedures abroad if available, as standard travel insurance policies may exclude elective treatments.