Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

Actress Lisa Ray was diagnosed with Multiple Myeloma, an incurable but treatable blood cancer, in 2009. She successfully went into remission but experienced a cancer relapse shortly after her wedding in 2012.

During her journey to recovery, she became a prominent advocate for cancer awareness and research. However, it was during this period, at the age of 37, that she also suffered chemo-induced menopause — a topic she brushed aside, not wanting to bring it up out of shame and fear, reflecting the taboo society still associates with the natural end of a woman’s reproductive phase.

In an interaction with HealthandMe, the Oscar-nominated film Water (2005) actress opened up about her experience with chemo-induced menopause.

“I went into chemo-induced menopause at 37. I was given no support. I was completely lost. And even for a subsequent decade after that, I couldn’t find any answers. I didn’t know how to take care of myself. I didn’t know I had options,” she said.

‘I Carried This Burning Secret Inside Me’

The actress shared that she normalized many of her symptoms and avoided speaking openly about menopause despite being candid about cancer.

“I was so vocal about cancer. I’m actually somebody who prefers to be quite truthful about what I’m going through. I don’t really like to hide things. I’m not secretive by nature. And yet, I carried this burning secret inside me for so many years,” she said.

“When I was being lauded as someone who was breaking through the silence of cancer, I was carrying the silent secret inside me. I couldn’t understand why for many years. And I realized today, I was carrying shame.”

She noted that menopause continues to remain a deeply misunderstood and under-discussed subject, despite affecting all women.

‘Menopause Was Like A Black Box’

Lisa said conversations around menopause were absent even within families.

“My mother never talked to me about menopause. Of course, we discussed my period when I got it, but menopause was simply like a black box,” she said.

The actress recalled that discussions around perimenopause and menopause only began when many of her close friends started experiencing symptoms themselves.

Calling the silence around menopause “astonishing” and “extremely unjust,” Lisa said women’s hormonal health continues to be severely underfunded and misunderstood globally.

“Menopause impacts all women. Yet it’s treated like a dark secret,” she told HealthandMe.

Lisa added that once she began researching the issue, she became increasingly frustrated by the lack of awareness and medical attention surrounding menopause and hormonal health.

Menopause Not Getting Enough Attention

The actress said that after moving to Dubai, she began openly discussing menopause on social media, despite initially worrying about public reaction.

“Sometimes in social settings, women would almost shut down or turn away and say, ‘Don’t talk about that.’ But when I put it on social media, maybe it permitted a lot of other women to also find a place to have a conversation or a community,” she said.

To bring about change where women can speak freely about the topic and seek treatment early, Lisa has co-founded NuHer, a science-backed health clinic and platform dedicated to midlife care for women. It is designed to support perimenopause and menopause through personalized medical treatments, clinical psychology, and nutritional guidance.

When asked why she chose to focus on menopause and women’s hormonal health, the Four More Shots Please! actress stated, “Menopause is simply not getting the attention that it needs. Women are struggling to get the care that they need and understand their options.”

Lisa explained that while awareness around cancer has steadily improved in India since her multiple myeloma diagnosis in 2009, menopause remains “the next taboo or frontier.”

According to Lisa, NuHer aims to create a safe, science-backed space where women can access support without judgment or dismissal.

“We need a place where women can be heard, where they’re not dismissed, where they’re not gaslit, where they receive all the right science and the options they can choose for this journey,” she told HealthandMe.

She also criticized the tendency to dismiss menopausal symptoms as a “normal” part of aging without offering support or treatment options.

“Women are not broken. Menopause is not a disease like cancer that has to be cured. But women need support. We don’t need to normalize suffering,” Lisa said.

Menopause Is 'Stepping Into Our Power Age’

Speaking about aging and post-menopause life, Lisa argued that society often dismisses older women despite what she described as a biologically important phase of life.

“We’ve had terrible PR as aging women. We are dismissed and considered irrelevant when actually we’re stepping into our power age if we know how to take care of ourselves,” the acclaimed actress told HealthandMe.

However, the problem arises when menopause is left unaddressed, and the hormonal changes cause long-term health impacts, including bone health, heart disease risk, and possibly dementia.

“The problem is with the drop in hormones. If you don’t have strategies and lifestyle changes to support yourself post-menopause, you become a frail woman. Your bones suffer. You’re more prone to heart disease and possibly even dementia,” she said, urging more women to seek medical help during menopause and not suffer in silence.

GLP-1 agonist drugs like Ozempic, Mounjaro, and Wegovy, may not only help treat obesity and diabetes but also improve survival among breast cancer patients, according to a new study.

The research published in JAMA Network Open suggests that the GLP-1 agonist drugs can lower deaths in breast cancer patients as well as cut down the risk of recurrence of the deadly cancer.

Breast cancer patients who used GLP-1 RA had an overall lower risk of death from any cause over a 10-year follow-up period.

Similarly, breast cancer survivors who used GLP1-RAs for diabetes or obesity had a significantly lower risk of their cancer returning over 10 years following their initial treatment.

"This study suggests that GLP-1 drugs may offer protective benefits, potentially improving survival and recurrence risk in some female patients with breast cancer—whether this is related to weight control, improved cardiovascular health, or other mechanisms remains to be studied," said study senior author Bernard F. Fuemmeler, Chair in Cancer Research at Virginia Commonwealth University’s Massey Comprehensive Cancer Center.

The findings were based on a retrospective cohort study examining the electronic health records of more than 840,000 breast cancer patients who were diagnosed between 2006 and 2023 and also were obese or had type 2 diabetes.

GLP-1 Drugs And Breast Cancer

Also read: World Hypertension Day 2026: Why Switching Salt May Be India’s Simplest Weapon Against High Blood Pressure

Widely hailed as a medical breakthrough, the GLP-1s (glucagon-like peptide-1 receptor agonists) act like the gut hormones that regulate appetite and blood sugar.

It acts specifically on obesity and diabetes — well-established risk factors that significantly elevate the risk of breast cancer progression and recurrence.

GLP-1 medications help lower the risk of breast cancer by promoting weight loss and decreasing circulating tumor activity. It also lowers blood sugar.

Studies have showed that people taking GLP-1s also experience fewer chemo side effects. They were less likely to have anemia, blood clots in veins, low levels of white blood cells called neutrophils, low blood platelet count, sepsis, nausea and vomiting, fatigue, cardiomyopathy, and neuropathy after chemotherapy.

However, the Virginia Commonwealth University study researchers noted that further studies are needed to understand the biological mechanisms, if any, between GLP-1 RAs and breast cancer outcomes.

Global Burden of Breast Cancer

Read: High Blood Pressure? Daily Soy And Legume Intake May Help Lower The Risk: Study

Breast cancer is the most diagnosed cancer worldwide, accounting for over 2.3 million new cases annually.

According to the WHO's International Agency for Research on Cancer (IARC), it is the leading cause of cancer-related deaths among women, resulting in roughly 670,000 deaths globally each year.

It is also one of the most common cancers among women in the US, and accounts for nearly one-third of all female cancer cases.

The average risk of a woman in the US developing breast cancer sometime in her life is about 13 per cent.

Breast cancer patients who are also obese or have type 2 diabetes experience more aggressive cancer growth and worse outcomes. Prior studies have shown that weight loss treatment and surgery following a breast cancer diagnosis are associated with improved heart health and increased survival.

-Walk into any salon, and you'll be offered a facial for almost every skin concern under the sun. But somewhere along the way, targeted treatments like de-tanning started giving traditional facials a real run for their money. If your main concern is sun damage, uneven tone, or that stubborn dullness that builds up over weeks of stepping out, the de tan vs facial debate is worth having properly.

The perfect de-tan face mask used consistently at home can deliver results that genuinely rival a salon treatment. It helps you in targeting pigmentation and sun damage right at the source without the appointment, the wait, or the cost. What keeps those results going between sessions is just as important. A daily de-tan face wash helps prevent surface tan from quietly rebuilding.

So eventually your skin holds onto its progress rather than starting from scratch every week. Here's a proper breakdown of the difference between de-tan and facial so you can make the right call for your skin.

De Tan Vs Facial for Oily Skin

The core difference comes down to what each treatment is actually designed to do.

De Tan is a targeted treatment built around one primary goal. It aims to dissolve surface-level pigmentation and sun damage. It is made up of chemical exfoliants like AHAs, brightening ingredients like vitamin C or kojic acid, and clay formulas that peel away tanned, dead skin cells to expose younger skin underneath.

A facial is a multi-step ritual that addresses overall skin health, not just one specific condition. It usually comprises cleansing, exfoliating, steaming, extraction, massage, and masks. Each phase has a particular objective. A facial is a great way to boost circulation, tackle a range of skin issues all at once, and give your skin a really good refresh.

Maintaining De-Tan Results at Home: A Wiser Approach

Including a targeted de-tan mask in the weekly regimen can help those who want to keep their skin more even-toned and brighter in between salon visits. Exfoliating acids, oil-balancing clays, and barrier-supporting elements fuel a product that targets dullness, uneven texture, and stubborn tan without stripping the skin.

Products like the Foxtale Skin Radiance De-Tan Mask are particularly helpful for oily, mixed, and sun-exposed skin types since they combine light exfoliation with skin-brightening treatment. Over time, a de-tan treatment at home may make skin seem brighter, fresher, and more radiant when used regularly in conjunction with daily sunscreen.

Which One Suits Your Skin Type?

Oily & Acne-Prone Skin

For oily and acne-prone skin, a targeted de-tan treatment is almost always the safer choice over a traditional facial. Most salon facials designed for brightening use heavy cream-based products, facial massages with oils, and steam, all of which can aggravate acne, clog pores, and trigger fresh breakouts on skin that's already overproducing sebum.

When you use a detan mask with Kaolin Clay and AHAs, it controls excess oil and pigmentation. It does all this without introducing anything that worsens breakouts for you. If you have oily skin, at-home detan treatments done consistently outperform most salon facials in both safety and visible results.

Dry & Dehydrated Skin

A traditional facial that includes a hydrating massage and a nourishing mask can work well here because it addresses moisture levels alongside surface concerns.

That said, a detan treatment isn't off the table for dry skin. The key is picking the right formula, one that uses gentler AHAs like Lactic Acid rather than stronger Glycolic Acid, and that includes hydrating ingredients like Ceramides or Hyaluronic Acid to counterbalance the exfoliation.

Dull & Sun-Damaged Skin

When the skin is suffering from a noticeable tan, uneven tone, and stubborn dullness from sun exposure, a detan treatment is the gold standard of 2026. A facial can provide a glow to your overall tone, but it doesn’t target the melanin deposit that produces your tan and pigmentation. A detan mask with Glycolic Acid, Niacinamide, and brightening clays works on the actual source of the problem, and with consistent use, the results compound over time in a way that a monthly salon facial simply can't replicate.

Which Works Better for Pigmentation and Sun Damage?

Here's a simple way in which you can decide:

Choose a De-Tan when:

• Your main concern is tan, uneven skin tone, or post-sun pigmentation
• You prefer to have targeted, efficient results at home without salon visits
• Your skin is oily or acne-prone and reacts badly to heavy facial products
• You need something you can do consistently every week as part of your routine
• You've just come back from a trip, a wedding season, or an extended time outdoors, and need to reset your skin quickly.

Choose a Facial when:

• Your skin needs an overall reset, not just brightening, but deep cleansing, circulation boost, and hydration together
• You're dealing with multiple concerns at once and want a professional to assess and treat your skin
• Your skin is dry or mature, and benefits from the massage and nourishment steps a facial includes
• You want a one-time intensive treatment before a special occasion rather than an ongoing routine fix.

For most people, the best approach isn't choosing one over the other permanently. In fact, you should understand when each serves your skin best and use them accordingly. A weekly de-tan treatment at home, with an occasional facial when your skin needs a deeper reset, covers most bases without overcomplicating your routine.

Can You Use a De-Tan Mask Instead of a Facial?

The facial vs de-tan debate doesn't have a single winner. It actually depends entirely on what your skin is dealing with and what goal you are trying to achieve. If you have issues with tan, pigmentation, and sun damage, a dedicated detan treatment is a better option for you.

Overall skin health, hydration, and multi-concern maintenance are where a facial earns its place. Know what your skin needs, pick the right tool for the job, and stay consistent; that's where the real results come from.