Most people are aware of type 1 and type 2 diabetes, but did you know there is a type 3 diabetes as well! It is a more obscure term. Although it is not an accepted medical diagnosis, type 3 diabetes has been discussed in the literature as a possible relationship between insulin resistance in the brain and Alzheimer's disease. This link has been described to help explain how metabolic disorders impact brain health, causing cognitive decline and dementia.

What is Type 3 Diabetes?

Type 3 diabetes is more of a misnomer because it should not be confused with type 3c diabetes, which relates to pancreatic dysfunction. The term "type 3 diabetes," on the other hand, has been loosely used by some scientists to analogously propose that Alzheimer's disease is strongly implicated with insulin resistance in the brain.

This concept was conceptualized by Dr. Suzanne de la Monte and Dr. Jack Wands of Brown University in the year 2008. This hypothesis postulated that Alzheimer's disease may be called type 3 diabetes for it bears many similarities with glucose metabolism disorder type 2 diabetes. Their concept arises from the basic principle that insulin is fundamental to blood sugar regulation, but it is also the case with the brain. When brain cells become insulin-resistant, they lose access to glucose, impairing their function.

Research published in the Journal of Diabetes Science and Technology supports this hypothesis by indicating that insulin resistance can be a significant contributor to the occurrence of dementia, also referred to as Alzheimer's. The symptoms of memory loss and diminished reasoning are associated with impaired glucose metabolism in the body, especially in the cerebral tissue.

Symptoms of Type 3 Diabetes

Although type 3 diabetes is not a "medical term," its symptoms correlate well with Alzheimer's diseases that are known to reduce the ability to think in an efficient manner and bring down brain health. These signs are:

- Loss of memory, especially short-term.

- Poor judgment and judgment ability

- Failure in recognizing people or places familiar once.

- Failure in the process of reading, writing or processing numbers

- Anxiety, agitation, or mood changes.

- Disorganized thoughts or confusion

- Lack of impulse control

As the disease advances, patients may be afflicted with severe complications including an inability to swallow or control their bodily functions. In the final stages, most patients die from fatal complications such as aspiration pneumonia.

Causes of Type 3 Diabetes

This may not be well understood with regards to type 3 diabetes, or the exact link between insulin resistance and Alzheimer's disease. Some identified contributing factors include the following:

1. Insulin Resistance

Insulin acts as an important regulatory mechanism of brain functions such as memory and cognition. The reduction in insulin signaling may impair metabolism of brain cells, thus bringing about neurodegeneration.

2. Type 2 Diabetes

These diseases show a strong relationship and those individuals diagnosed with type 2 diabetes have double chances of getting Alzheimer's. In the two, the main causes can be chronic inflammation, oxidative stress, and a defect in glucose metabolism.

3. Environmental and Lifestyle Factors

Insulin resistance associated with obesity, stress, and an unhealthy diet is considered a cause that may increase the chances of Alzheimer's disease.

Researches in Frontiers in Neuroscience and The Lancet Neurology have also highlighted that drugs used for antidiabetic medication may be crucial for the prevention or at least slowing down the course of Alzheimer's.

Treatments for Type 3 Diabetes

In 2022, in a study in Pharmaceuticals, researchers studied biomarker uptake in brain regions implicated in the faulty uptake and metabolism of blood sugar in Alzheimer’s patients.

Emerging Therapies

Research into such treatments as intranasal insulin has also been promising. Intranasal delivery of insulin directly to the brain has been reported to enhance glucose uptake by brain cells, improve memory, and boost cognitive performance. While such clinical trials have been shown to be successful, additional research is needed for safety and efficacy.

Medications

For patients being aggressive or agitated, antipsychotic drugs may be prescribed; however, therapies such as cognitive rehabilitation as well as cognitive stimulation therapy serve to preserve memory and executive function.

Lifestyle Interventions

Diet, exercise, and stress management are critical in preventing and managing insulin resistance. A review in the Journal of Alzheimer's Disease also highlighted the benefits of Kirtan Kriya meditation, which can regulate genes involved in insulin and glucose metabolism, improve sleep, and reduce inflammation.

Can Type 3 Diabetes Be Prevented?

Although type 3 diabetes is not officially recognized, its connection to Alzheimer’s disease underscores the importance of proactive measures for brain health. Some prevention strategies include:

1. Healthy Diet

Consuming a balanced diet rich in antioxidants, whole grains, and healthy fats may support brain health.

2. Regular Exercise

Physical activity improves insulin sensitivity, reduces inflammation, and enhances overall metabolic health.

3. Stress Reduction

Mindfulness practices, including meditation, have been shown to lower stress levels, which can reduce the risk of cognitive decline.

The term type 3 diabetes brings out the complex relationship between metabolic disorders and brain health. Even though it is not a recognized medical condition, the concept emphasizes the crucial role of insulin in brain function and its possible contribution to Alzheimer's disease. Continued research will hopefully provide hope for therapies such as intranasal insulin and lifestyle modifications.

The World Health Organization (WHO) noted that menopause often goes unnoticed as a clinical priority, observing these unmet needs, the state governments in Maharashtra and Kerala will soon launch government-run menopause clinics. These clinics will have specialized support systems designed to offer holistic healthcare services for menopausal women within the public system.

These clinics will also have medical consultations, mental health counselling, targeted screening services and lifestyle guidance.

What Are Menopause Clinics?

Menopause clinics are specialized healthcare units, usually housed in government hospitals, urban health centres or district hospitals, that focus on both the medical and emotional needs of women transitioning through menopause. Rather than brushing menopause aside as a “natural” phase that needs little attention, these clinics offer organized, evidence-based care that goes well beyond routine outpatient visits.

At the heart of a menopause clinic is a comprehensive, integrated approach that includes:

• Clinical assessment of menopausal symptoms
• Screening for hormonal and physical health issues, such as bone health and heart disease risk
• Mental health support and psychosocial counselling
• Personalized advice on lifestyle, nutrition and mid-life wellness
• Ongoing patient education and structured follow-up

By bringing these services together under one roof, menopause clinics help women cope with day-to-day symptoms while also addressing long-term risks like osteoporosis, metabolic changes and a higher likelihood of cardiovascular disease.

What Is Menopause?

This is the natural, permanent end of menstruation defined as 12 consecutive months without a period. This typically occurs between ages 45 to 55.

Foods That May Help During Menopause

• Soy: A top source of phytoestrogens, particularly isoflavones, which bind to estrogen receptors in your body. Studies suggest soy may help alleviate hot flashes, improve cholesterol levels, and even reduce the risk of heart disease during menopause.
• Flaxseed: Packed with lignans, a type of phytoestrogen with mild estrogenic effects, flaxseed may also offer some relief.

Including these foods in your diet could help ease symptoms and reduce your risk of certain menopause-related conditions.

Why a Balanced Diet Matters

A nutrient-packed, balanced diet is the foundation of good health at any age. Prioritize:

• Vegetables and fruits: Rich in vitamins and antioxidants.
• Whole grains: Great for maintaining steady blood sugar levels.
• Lean proteins: Support muscle health and repair.
• Low-fat dairy: Provides calcium for bone strength.
• Avoid ultra-processed junk foods, excessive sugar, and unhealthy fats, which contribute little beyond empty calories.

Maharashtra Menopause Clinic

Earlier this January, the Maharashtra government rolled out the country’s first state-run menopause clinics across government hospitals and urban health facilities. The initiative was launched on Makar Sankranti, January 14, under the guidance of Minister of State for Health Meghna Bordikar.

As per official statements, these clinics are designed to offer end-to-end care in one place. Services include expert medical consultations to evaluate and manage menopausal symptoms, mental health support to address emotional and psychological concerns, and screenings for bone health, cardiovascular risk and hormonal balance. Medicines and follow-up advice are also provided during the same visit, cutting down the need for multiple referrals and repeat hospital trips.

A senior health official pointed out that while menopause is a natural life stage and not a disease, many women need consistent physical and emotional support during this transition. The strong response from women across Maharashtra highlights a long-standing gap in healthcare, where menopause-related concerns often went unaddressed due to the absence of dedicated services. With this move, Maharashtra has also set an example for other states looking to introduce gender-specific care within public health systems.

Read: Can Your Diet Affect Menopause?

Kerala follows with dedicated clinics

Taking a cue from Maharashtra, the Kerala government has announced plans to set up specialized menopause clinics in district hospitals. An initial allocation of Rs 3 crore has been earmarked for the project in the 2026 state budget, presented by Finance Minister K N Balagopal.

The proposed clinics in Kerala will follow a similar model, offering medical consultations for menopausal symptoms, mental health counselling, and screenings for heart, bone and hormonal health. Women will also receive medicines along with lifestyle and dietary advice at a single facility.

The initiative acknowledges the wide-ranging impact of menopause, including hormonal changes, sleep disturbances, bone health issues and increased stress, and aims to create a one-stop support system within district hospitals. By bringing menopause care into mainstream public healthcare, Kerala hopes to improve access, reduce stigma and ensure that women receive timely, structured support during this phase of life.

Bruce Willis was diagnosed with frontotemporal dementia in 2022. His wife, Emma Heming Willis recalled the day when Bruce was diagnosed with the condition and how it made her feel "lost, isolated and afraid." Talkin to PEOPLE, Emma said, Bruce "never connected the dots" that he has been diagnosed with frontotemporal dementia. “I think that's like the blessing and the curse of this, is that he never connected the dots that he had this disease, and I'm really happy about that. I'm really happy that he doesn't know about it,” she shared about Bruce, 70.

Bruce Willis' Diagnosis

"On the day Bruce got his diagnosis, we walked out of the doctor's office with a pamphlet and an empty goodbye. No plan, no guidance, no hope, just shock," she explained in front of a packed auditorium, People reported.

In one instant, the family's future disappeared. The Oscar-winning actor, famous for his quick wit and performances in Die Hard and The Sixth Sense, would be leaving his career behind. Emma found herself thrust into a whole new role of full-time caregiver at the same time.

She continued to explain, "I found myself having to keep my family intact, raise our two small girls, and tend to the man that I love while dealing with an illness I hardly knew anything about."

Emma's emotional candor resonated with hundreds of families who have received similar diagnoses and encouraged her to author a book, The Unexpected Journey, scheduled for publication in September. In Emma's words, "This is the book I hope will assist the next caregiver. It is packed with encouragement, wisdom, and the encouragement necessary to walk this path.

Read: Bruce Willis’ Dementia Diagnosis Left Wife Emma Heming Feeling ‘Lost’ And ‘Isolated’ - What Are The Signs Of Caregivers Burnout?

What Is Frontotemporal Dementia?

Frontotemporal dementia is a less prevalent type of dementia that mainly occurs in the frontal and temporal lobes of the brain. It tends to affect behavior, personality, language, and movement more than memory, particularly in its initial stages.

In contrast to Alzheimer's, which generally strikes older individuals, FTD can hit at an earlier age—sometimes as young as 40. The symptoms can range from changes in personality, emotional flatness, or the inability to show empathy to impulsiveness, so it is especially hard for spouses and children to cope.

Emma's case illustrates how abrupt and disrupting this diagnosis can be—not only for the patient but for caregivers as well.

Whereas Bruce Willis' diagnosis hit global headlines, the mental toll taken by Emma, his caregiver, was largely in the background—until she decided to come forward.

Caregiving is a respectable position, but it's also a challenging and thankless one. For those who are caring for loved ones with dementia or other chronic illnesses, the stress of "keeping it all together" can result in a condition called caregiver burnout.

"Caring for someone is the most intimate and demanding work of love," Emma explained, "but when you're not noticed or supported, it begins to undermine your health—mentally and physically."

Work stress could make you gay, said a Malaysian minister Zulkifli Hasan, as continued government intervention of what is described as 'sexually deviant behavior' has pressured the country's LGBTQ community. This happened two weeks after religious authorities and police acted on complaints from a sultan and Islamist politicians that a camping retreat was promoting the LGBTQ lifestyle, reported South China Morning Post.

Religious Affairs Minister Hasan on Tuesday said that work stress could be among many other factors that is pushing people into sexual orientations other than heterosexuality. “Societal influence, sexual experiences, work stress and other personal factors come under this category [of possible causes],” Zulkifli said in a written parliamentary reply to a question by Siti Zailah Mohd Yusoff, a lawmaker with the opposition Islamist party PAS.

Also Read: Andy Kershaw Diagnosed With Spinal Cancer That Left Him Unable To Walk

He cited a 2017 study by Sulaiman et.al., that said such elements "can contribute to the increase in LGBT acts".

His comments have attracted a lot of backlash, with many people on social media mocking him. A social media user Muaz Zam said, "By this logic, I am genuinely shocked my entire office isn't gay by now". Another one read: "In other words: they never work hard in the parliament."

However, these claims are not scientifically back. Work related stress can impact a person, but cannot change their sexuality. It can, however, cause health effects. What it does not do is change one's sexuality and this is why one should know the difference about gender, sex and sexual orientation or sexuality.

'Work Stress Makes You Gay': The Difference Between Gender vs Sex

While these both terms are often used interchangeably in official forms, there is a difference between the two.

As per the Council of Europe, gender is an area that cuts across thinking about society, law, politics, and culture.

Read: Trump Administration Deadnames Transgender Former HHS Officer Rachel Levine in Official Portrait

Definition Of Gender vs Sex by WHO

The World Health Organization notes that sex refers to: "the different biological and physiological characteristics of males and females, such as reproductive organs, chromosomes, hormones, etc.”

Whereas, gender refers to: "the socially constructed characteristics of women and men – such as norms, roles and relationships of and between groups of women and men. It varies from society to society and can be changed. The concept of gender includes five important elements: relational, hierarchical, historical, contextual and institutional. While most people are born either male or female, they are taught appropriate norms and behaviours – including how they should interact with others of the same or opposite sex within households, communities and work places. When individuals or groups do not “fit” established gender norms they often face stigma, discriminatory practices or social exclusion – all of which adversely affect health."

Definition Of Gender vs Sex by The European Institute For Gender Equality

“Sex refers to the biological and physiological characteristics that define humans as female or male. These sets of biological characteristics are not mutually exclusive, as there are individuals who possess both, but these characteristics tend to differentiate humans as females or males.”

“Gender refers to the social attributes and opportunities associated with being female and male and to the relationships between women and men and girls and boys, as well as to the relations between women and those between men. These attributes, opportunities and relationships are socially constructed and are learned through socialisation processes. They are context- and time-specific, and changeable. Gender determines what is expected, allowed and valued in a woman or a man in a given context. In most societies, there are differences and inequalities between women and men in responsibilities assigned, activities undertaken, access to and control over resources, as well as decision-making opportunities. Gender is part of the broader sociocultural context. Other important criteria for sociocultural analysis include class, race, poverty level, ethnic group and age.”

The main difference is that gender is a social construct, whereas sex is the biologically labelled term based on organs and hormones.

Read More: Trump's Top Health Nominee Wants ‘Corrective Care’ For Trans People

What Is Sexuality?

As per the American Psychological Association (APA), sexuality is the capacity to derive pleasure from various forms of sexual activity and behavior. The Lanarkshire Sexual Health describes sexual orientation as a way to describe the feelings you have for someone you fancy or are attached to.

While sexuality can change overtime, it is not a choice. There is no evidence that sexual orientation can be forced to change through therapy.

Can Stress Impact Sexuality?

While stress can impact sexual function by reducing libido, causing fatigue, and triggering hormonal changes, it does not change one's sexual orientation. Jason Teoh, who writes on LGBTQ issues, project partner at NSW Department of Planning, Housing and Infrastructure, notes: "Sexual orientation is not caused by stress. It is not caused by trauma, influence or difficult life circumstances."

The WHO notes: sexual orientation is a natural, stable part of human identity shaped by biology, genetics, and early development. The WHO removed homosexuality from its disease classification in 1990. The American Psychiatric Association did the same in 1973.