As worldwide use of GLP-1 drug such as Ozempic and Mounjaro increase, medical experts are ringing the alarm over a bizarre new cosmetic side effect- loose skin on the feet. Ozempic, generic name semaglutide, was originally created to treat type 2 diabetes. Now it's a name on every lip for its unbelievable impact on weight loss. By mimicking the hormone GLP-1, it reduces hunger, decelerates digestion, and regulates blood sugar. But with the touted advantages comes a new and less sexy concern: Ozempic feet.

This is a slang term for visible signs of skin aging and sagging on the feet — a side effect now making its public debut thanks to social media gossip and sharp-eyed observers at celebrity makeovers. It's been added to a growing list of cosmetic issues like Ozempic face and Ozempic butt—terms used to describe the gaunt facial appearance and buttock deflation in some on these injectable medications.

What Is 'Ozempic Feet'?

'Ozempic feet' is a description of the creased, sloping skin and empty appearance of the feet — particularly at the top, where the skin is naturally thinner. This is due to a rapid and extreme reduction in fat reserves as patients lose weight. Unlike intentional body sculpting or fat reduction from exercise, weight loss with Ozempic is fast and even, subjecting areas that typically have small fat reserves, such as the feet.

Experts explain that the sudden and severe loss of fat leaves skin looking deflated, aged, or disproportionate to the rest of your body. Your feet don't have much cushioning to begin with. After the fat loss, you're left with wrinkled skin and a higher likelihood of experiencing pain when walking.

Essentially, the same drug that is helping drug users lose weight is giving them feet that look prematurely old without intending to.

The celebrity side effect was the subject of viral rumination following reports of speculation between followers that TV personality Sharon Osbourne and chat show host Oprah Winfrey may have 'Ozempic feet.' Sharon, 72, posted a snap with her grandson in April 2025 that prompted fans to comment upon an inconsistency between ageless looking face and sharply creased ankles. The reaction varied from worry to wonder, "Your ankles are giving your age away," a follower suggested.

Oprah Winfrey, 71, faced similar criticism when she showed up at the 55th NAACP Image Awards. Spectators commented on how loose her foot skin looked — a striking difference for someone who had seemingly shed almost 50 pounds on GLP-1 drugs.

Neither Osbourne nor Winfrey has indicated whether they attribute these differences to their weight-loss regimens, but the internet chatter has pushed the topic into the mainstream.

Is 'Ozempic Feet' a Cause for Concern?

While the term is likely to be ringing somewhat flippant or superficial in tone, it opens up into a wider, more serious discussion of the long-term impact of rapid medical weight loss.

Doctors note that any sudden change in weight — especially one achieved through drug methods — can affect soft tissue, elasticity of the skin, and distribution of fat. In a couple of cases, GLP-1 medication like Ozempic has been determined to cause treatment-induced neuropathy in patients with diabetes, producing symptoms of numbness, tingling, or burning sensations in the feet.

Healthcare professionals suggest the users to take care of their foot health very carefully. "If you notice changes in your feeling, persistent pain, or swelling, seek medical attention," says Dr. Weintraub. "Your feet also develop symptoms of nutrient deficiency or rapid muscle and fat loss which can affect your balance and stance."

Other Side Effects of Taking Weight Loss Drugs

As the fame of Ozempic shoots through the roof with nearly 1 in every 8 Americans having seemingly used GLP-1 medications by 2024, so has its psych effect.

A study indicated that the patients taking semaglutide were 195% more likely to suffer from severe depression and over 100% more likely to be suicidal. Even though both the U.S. FDA and the European Medicines Agency (EMA) have stated that no conclusive link has been made between Ozempic and suicidal thoughts, the increased number of reports is raising alarms.

These findings have prompted most health experts to emphasize the requirement for sustained assistance as well as frequent surveillance of individuals who take these drugs- physically as well as mentally.

Add to the complexity is the "rebound" phenomenon. Northwestern University studies indicate that patients who had stopped GLP-1 therapy regained nearly two-thirds of the lost weight. The reversal also logged increases in blood pressure, cholesterol, and risk for cardiovascular disease thus, lifestyle alteration and upkeep a priority, even after the drug.

Winfrey herself echoed those words in a recent interview, "These drugs are not a magic bullet. They're a tool, not a replacement for lifestyle change."

'Ozempic feet' is a superficial aesthetic issue, but it reflects on a larger narrative: the evolving landscape of weight loss pharmaceuticals. As ever more people pursue drugs to manage weight and comorbid risk, the focus must remain with overall well-being far and above the reading on the scale.

The international public health community was hopeful that polio—the crippling viral illness that previously paralyzed hundreds of thousands of children every year—was almost extinct. But in a concerning twist in 2025, the World Health Organization (WHO) has raised the alarm- polio is back, and eradication hangs in the balance.

In 2020, the world celebrated a milestone—polio was officially eradicated everywhere except two nations. But in the first quarter of 2025, an old nemesis has reappeared. Cases of wild poliovirus are again increasing in Pakistan and Afghanistan, the final two bastions of endemic transmission. Pakistan, which had reported 74 cases in 2024, has already seen 6 new cases this year. Afghanistan is not far behind with 1 reported case.

While the numbers are small in themselves, they portend a worrisome trend in a decades-long fight. Global health professionals point to interruptions of vaccine campaigns—interruptions they say are directly caused by deep reductions in international assistance.

One major factor behind this upsurge is the abrupt interruption of funding support from the United States Agency for International Development (USAID). USAID has long been a pillar of support for vaccination activities in polio-endemic and high-risk areas by financing personnel, logistics, vaccine sourcing, and outreach.

A private memo by Nicholas Enrich, USAID acting assistant administrator for global health, cautions that if these pauses in funding continue, we will witness another 200,000 cases of polio paralysis each year, and hundreds of millions more are at risk of being infected. The International Rescue Committee (IRC), which was carrying out polio vaccinations under the watch of the Ministry of Health and World Vision in Kenya, says its USAID-funded program was the initial one to close on January 31st.

"Right now, IRC support for polio immunization in Kenya's hard-to-reach areas has come to a halt," confirms Mohamed El Montassir Hussein, Kenya's IRC country director. Although local health officials are still immunizing, their efforts are strained without foreign funding.

Why Does Wild Polio Persist in Just Two Countries?

Pakistan and Afghanistan are the exceptions to an otherwise polio-free world. Several chronic challenges, according to experts, include unstable security environments, misinformation, religious and political opposition to vaccination, and weak health infrastructures. Additionally, vaccination teams working in war zones frequently encounter logistical challenges and safety threats.

The virus has been extremely resilient. It takes advantage of holes in immunity caused by lack of vaccinations. Adding to the problem is the presence of circulating vaccine-derived poliovirus (cVDPV)—an uncommon event whereby the attenuated virus contained within oral polio vaccines changes and becomes virulent again.

WHO Flags High-Risk Nations and Rising Global Concern

The WHO has listed five countries with the immediate risk of the international spread of polio:

• Afghanistan
• Pakistan
• Mozambique
• Democratic Republic of Congo
• Guinea

Furthermore, 35 nations have recorded imported cases of cVDPV type 2, while 10 countries continue to experience active circulation of wild-type or vaccine-derived poliovirus in the last 24 months. WHO's guidelines are:

• Improved vaccine coverage
• Increased access to healthcare in risk areas
• Travel restrictions for unvaccinated travelers from high-risk areas

But with more than $200 million in donor funding lost— including life-saving funds from the U.S. President's Emergency Plan for AIDS Relief (PEPFAR)—these guidelines encounter tremendous implementation challenges.

Hidden Cost of Underfunding Global Health

It is the invisible spread that makes the situation more threatening. Those countries with weak surveillance systems may not see early outbreaks until it becomes too late. In politically unstable or humanitarian crisis-affected areas, the virus can spread quietly among unvaccinated groups, only to spill over borders.

Polio flourishes in these crevices—between the unvaccinated, the untracked, and the neglected. And once it establishes itself, retaking control is that much harder and costly.

Although the numbers as they stand are alarming, they also create an opportunity for recommitment on a global scale. Global polio eradication has always been a collective endeavor. Today, more than ever, a concerted effort is needed.

WHO Director-General Dr. Tedros Adhanom Ghebreyesus reacted with strong concern over the diminishing U.S. support and asserted the urgency for international collaboration. "The precipitous cuts to U.S. funding also affect efforts to stop polio for good," he cautioned.

Relaunching public confidence in vaccines, maintaining secure access during times of conflict, reinstating funds channels, and reinforcing surveillance form part of the arsenal necessary to complete the mission against polio.

The resurgence of polio in 2025 is a wake-up call. It reminds the world that public health victories, no matter how close, can unravel quickly without consistent investment and collaboration.

Eradiating polio was never a matter of one country or one continent. It was about a shared global commitment. If the trend continues, we will risk wasting decades of progress—and allowing a preventable disease to reassert its hold on the world's most vulnerable.

For decades, the ideal age for women to become mothers was firmly rooted in the 20s—a peak period conventionally tied to prime fertility, social norms, and the onset of family life. However, recent information reveals a different picture, more women are increasingly opting to start families when they are in their 30s, although fertility does start decreasing with age. Based on initial data from the Centers for Disease Control and Prevention (CDC), women aged 30 to 34 now have more births than women in their late 20s, a big cultural and demographic change.

This article explores into what's behind this shift—from changing social values and economic considerations to medical innovations and individual empowerment.

In 2016, the CDC also said that the birth rate for women between the ages of 30 and 34 was 103 per 100,000, just barely above the 102 per 100,000 for women between the ages of 25 and 29. The mean age at which American women are giving birth to their first child has also increased to 28, from 26 only a few years earlier. This change signals something more than mere preference; it indicates greater systemic shifts within education, relations, and economic scenarios.

Women aged in their late 20s had the country's peak birth rates for over three decades. That storyline is being revised now. Authorities are attributing the change to a range of interrelated reasons—the primary among them being a decision to wait until marriage to come later in favor of a career or self-realization phase first.

Is Rise of Professional and Financial Independence the Reason?

Women of the millennial and Gen Z generations are entering a job market where education and career mobility are prized—and in many cases, a necessity for financial security. With women becoming more prevalent in positions of leadership within industries and with record-breaking levels of educational attainment, motherhood is no longer viewed as a duty of youth but as a thoughtful life choice.

Waiting until later to have a child offers the time necessary to acquire financial stability, establish a robust professional base, and even eliminate student loans. These actions are important in an environment where living costs and child-rearing—particularly in metropolitan areas—keep increasing.

Deeply connected to this movement is the shifting attitude toward marriage. The first marriage age in America has climbed to 27 for women, a drastic increase over earlier generations. As people delay marriage or pursue alternative relationship structures, the timing of having children has naturally followed suit.

Relationship expert Bill Albert of the National Campaign to Prevent Teen and Unplanned Pregnancy observes that cultural trends, such as the continued decline in teen pregnancies, are part of a larger movement toward thoughtful parenting—where a person is prepared emotionally and economically before assuming the responsibility of bringing a child into the world.

Fertility, Egg Freezing, and Reproductive Health Awareness

Although the social clock might be ticking later, biology hasn't. A healthy woman has approximately a 20% chance of conceiving in any menstrual cycle in her 20s, says the American Congress of Obstetricians and Gynecologists. Fertility, however, starts to decline in the early 30s and declines more steeply after age 37.

Despite this, women are becoming more attuned to these biological facts—and are doing something about it. Egg freezing is becoming a proactive solution, enabling women to freeze their eggs as they work toward other objectives in life. Even though the treatment is expensive (usually more than $10,000, with yearly storage charges), its popularity speaks volumes for the contemporary woman's willingness to seize control of her reproductive destiny.

Infertility Support and Treatment Options

To those who do experience fertility issues, advances in medicine have made family creation more possible than ever. The CDC reports that approximately 11% of women aged 15 to 44 have utilized infertility services, and the Mayo Clinic explains several causes—ranging from ovulation problems and PCOS to endometriosis and cancer treatment complications.

For couples seeking to become pregnant, lifestyle issues such as smoking, weight imbalance, and stress can be factors as well. Health professionals advise women older than 35 to have an evaluation after six months of failing to conceive—six months less than for younger women. With various treatments such as IVF, hormone therapy, and assisted reproductive technologies, increasing numbers of women in their 30s are having successful pregnancies despite the loss of function that comes with age.

Emotional Readiness and the Psychology of Modern Motherhood

Aside from biology and economics, there's the issue of emotional readiness. Women say they feel more grounded, self-assured, and self-aware in their 30s. They've had time to travel, learn, experience the world, and develop a strong sense of self prior to embracing the challenging and life-altering role of motherhood.

This emotional maturity will also feed through into more secure parenting arrangements and more settled family lives. More mature age at motherhood will also include women who have long-term partnership experience and securely structured support networks behind them.

The motherhood narrative is shifting. Women today are rewriting the playbook, using fertility with deliberation and knowledge, and turning conventional wisdom on its head when it comes to the "right" time to have children. While age still plays a huge role in reproductive health, it is no longer the sole factor.

As the world continues to evolve—socially, economically, scientifically, it's bound to happen more and more often that women continue to look on their 30s not as a deadline but as an opening. And as they gain ever-improved access to fertility procedures, as wider society offers their support, as medicine makes breakthrough after breakthrough, they'll have more control over motherhood than ever before to enter into when they want.

What started out as a persistent cough while pregnant almost turned into a tragedy for 26-year-old Illinois' MaKenna Lauterbach. At 36 weeks' pregnancy, the would-be mom thought that her symptoms were normal for pregnancy exhaustion in late stages—until she started gasping for air from doing minor chores. What ensued was a time-sensitive, life-saving battle of wits between world-class experts, state-of-the-art medical treatments, and an outcome against all odds.

Pregnancy tends to be accompanied by fatigue, shortness of breath, and changing physical needs. So when MaKenna began feeling breathless and having a persistent cough while caring for her horses, she attributed it to third-trimester exertion. Walking to the barn made her breathless—as if she'd run a marathon. But her symptoms did not get better, and by the time she was full term, her condition had progressed dramatically.

Even with her deteriorating symptoms, imaging tests were initially shunned. Medical staff are naturally averse to putting pregnant women through the stress of radiation exposure, particularly when in the late stages of pregnancy. But MaKenna's condition rapidly worsened—coughing gave way to vomiting and intense respiratory distress, prompting emergency admission to hospital.

Just a few days from her due date, imaging at last showed the devastating discovery—a grapefruit-sized tumor wedged in her chest, obstructing the artery to her right lung. The tumor was suffocating her airway and threateningly restricting oxygen delivery, placing mother and baby alike in danger.

MaKenna was flown to Northwestern Memorial Hospital in Chicago, where she was admitted to the intensive care unit. Within a short time after arrival, she went into labor. Her blood pressure rose, the baby became distressed, and physicians realized that they had only hours—possibly minutes—to move.

"Her lungs were impaired because of the tumor, and labor was also slowing her down to breathe. The danger of respiratory failure and cardiac arrest was very real," said Dr. Lynn Yee, a maternal-fetal medicine specialist at Northwestern Medicine.

MaKenna was put on extracorporeal life support (ECMO)—a life-supporting device that circulates oxygenated blood outside of the body—and received an emergency C-section. Her baby boy, Colter, was delivered safely, healthy in spite of the wild ride he had getting here.

For MaKenna, there was a mix of joy and fear. "Because of the tumor, the delivery came so rapidly. I was mourning the birth plan I had been planning for months, while also coping with the news of my surprise diagnosis," she explained.

What is Rare and Aggressive Melanoma?

After the birth, physicians initiated additional tests. A bronchoscopy test showed the tumor was stage 3 melanoma—a skin cancer that had somehow traveled and developed inside her chest.

This posed a singular challenge. "There isn't much written about or a lot of published cases on how to treat melanoma that comes in this way," said Dr. Kalvin Lung, a thoracic surgeon at Northwestern Medicine. "We had to fall back on the knowledge our team has gained from years of taking care of complex thoracic cases."

Prior to surgery, doctors gave three doses of immunotherapy to shrink the tumor. The therapy was effective in diminishing its size from 13 centimeters to 9 centimeters, thus enabling the subsequent action—surgery.

The procedure itself was extremely complicated. Dr. Lung and Dr. Chris Mehta, a cardiac surgeon with Northwestern Medicine, were required to remove MaKenna's right lung entirely, part of the pulmonary artery, and related lymph nodes. The tumor had invaded large blood vessels and spread throughout all three lobes of the right lung. "We may have a case like this every few years," said Dr. Mehta.

Now 27, MaKenna is stable and continues her immunotherapy treatments. Her scans show no new signs of metastatic cancer, and the tumor site remains inactive. She’s focusing on motherhood, recovery, and gratitude.

“Colter is the best baby—always smiling and sleeping through the night,” she said. “I can’t say enough about the incredible medical team that saved my life. Because of them, I’m here today.”

Dr. Yee continued, "To see MaKenna doing so well, and Colter thriving, brings tears to my eyes. It demonstrates what coordinated, compassionate medical care can do."

Can Pregnancy Shadow Life-Threatening Illnesses?

Pregnancy is commonly accompanied by a variety of physical changes—fatigue, shortness of breath, backaches, nausea, and swelling. Although these symptoms are typically harmless, they sometimes mask the signs of serious underlying medical conditions. This crossover between normal pregnancy pains and signs of potentially fatal diseases can mean that the illnesses are not diagnosed until late, as in the recent case of MaKenna Lauterbach—a 26-year-old woman whose relentless cough and shortness of breath throughout her pregnancy proved to be stage 3 melanoma in her chest.

Shared Symptoms of Pregnancy and Illness Mimic One Another

Most life-threatening conditions have symptoms that are identical to those of pregnancy. Diseases such as heart disease, blood clots, infections, and even cancer may appear with fatigue, chest pain, shortness of breath, or swelling—commonly attributed to normal pregnancy complaints. This similarity results in a diagnostic blind spot.

For example:

• Shortness of breath can be due to increased oxygen demand during pregnancy but can also result from lung disease or heart failure.
• Swelling in late pregnancy is normal but may indicate preeclampsia, kidney disease, or a tumor compressing veins.
• Nausea and vomiting are usual in the first trimester but may also obscure gastrointestinal cancers or liver disease.

Hesitation With Diagnostic Imaging in Pregnancy

One of the greatest difficulties is that physicians tend to shun some diagnostic tests such as X-rays, CT scans, or MRIs during pregnancy in order to avoid exposing the fetus to radiation. Although this prudence is necessary, it can lead to life-threatening delays if a critical condition is suspected but not diagnosed. In MaKenna's situation, imaging was delayed until her symptoms became critical—by that time, a tumor had obstructed large lung arteries.

Immune and Hormonal Alterations Can Speed Up Underlying Disorders

Pregnancy dampens some immune reactions to shield the developing fetus. Yet, this changed immune environment can give rise to or speed up latent diseases like cancer, autoimmune disorders, or infections. Hormonal spikes can also nourish hormone-sensitive tumors, elevating the risk of complications.

Fetal Over Maternal Prioritization in Emergency Situations

During emergencies, choices are frequently made to safeguard the baby—even at the expense of delaying the mother's treatment. This preference can make cases more complex when the mother's declining health impacts fetal welfare directly. Delayed diagnosis or treatment of maternal illness can put both lives at increased risk.

Emotional and Cognitive Biases

Numerous pregnant women—such as MaKenna—will minimize their symptoms, assuming they are just a result of pregnancy demands. There is also a cultural pressure to suffer through pregnancy, and this can cause women not to speak up or seek second opinions when something does not feel right.

Pregnant patients with severe medical issues frequently need treatment from several specialists: obstetricians, oncologists, cardiologists, or pulmonologists. Without an integrated and coordinated effort, important warning signs can be overlooked or insufficiently explored. MaKenna's survival was partly because of the rapid collaboration between maternal-fetal medicine, thoracic surgery, oncology, and intensive care specialists.

Pregnancy never needs to stand in the way of diagnosing and treating potentially life-threatening diseases. Awareness, early investigation, and multidisciplinary care are critical in distinguishing normal pregnancy symptoms from red flags. Pregnant women must always feel confident enough to voice their concerns, clarify the situation, and stand up for their well-being—because, as MaKenna's experience demonstrates, an early diagnosis can save not just one, but two lives.