Diabetes insipidus (DI) is a rare medical condition that disrupts the body's ability to regulate water, resulting in excessive thirst and an unusually high volume of urine. This condition affects the kidneys' ability to concentrate urine and causes individuals to produce between 3 and 20 quarts of dilute, colourless urine daily, compared to an average of 1 to 2 quarts. It is pertinent to note that DI is not related to diabetes mellitus, which disrupts the body's insulin production.

Types Of Diabetes Insipidus

This condition results from damage to the hypothalamus or pituitary gland, which impairs the production or release of vasopressin, a hormone responsible for water retention. When vasopressin levels are inadequate, the kidneys fail to conserve water, leading to excessive urination. It can result from Brain injuries or surgeries, tumours, infections or inflammation and aneurysms.

Nephrogenic Diabetes Insipidus

This type occurs when the kidneys fail to respond to vasopressin, causing excessive fluid loss. Common triggers include chronic kidney disease, and electrolyte imbalances, such as high calcium or low potassium levels. Additionally, medications like lithium

and urinary tract blockages can also cause Nephrogenic DI.

Gestational Diabetes Insipidus

A rare condition seen only during pregnancy, this occurs when the placenta produces an enzyme that breaks down vasopressin or increases prostaglandin levels, reducing kidney sensitivity to the hormone. Symptoms of this are usually mild and often resolve postpartum but can recur in future pregnancies.

Symptoms And Warning Signs

• Severe thirst, often leading to the consumption of over a gallon of water daily
• Frequent urination (polyuria), sometimes exceeding 20 quarts per day
• Nighttime urination and bed-wetting
• Weakness, muscle pain, and preference for cold drinks

In severe cases, dehydration may develop, manifesting as fatigue, dizziness, dry mouth, confusion, nausea, or fainting. Infants and children with DI may exhibit crankiness, poor feeding, slow growth, fever, or vomiting.

Causes And Risk Factors

DI stems from issues with vasopressin production or response. Central DI arises from damage to brain structures, while nephrogenic DI relates to kidney dysfunction. Risk factors include:

- Genetic mutations affecting water regulation

- Certain medications like diuretics or lithium

- Metabolic disorders that alter calcium or potassium levels

- Brain injuries or surgeries

Diagnosis And Testing

Diagnosing DI involves a combination of medical history, physical exams, and specialized tests:

- Urinalysis: Evaluates urine concentration and glucose levels to distinguish DI from diabetes mellitus.

- Blood tests: Check electrolyte, glucose, and vasopressin levels.

- Water deprivation test: Measures changes in weight, blood sodium, and urine concentration during fluid restriction.

- MRI: Detects abnormalities in the hypothalamus or pituitary gland.

- Genetic screening: Identifies inherited risk factors.

Although DI is rare, affecting about 1 in 25,000 people, early diagnosis and targeted treatment can significantly improve quality of life. Researchers continue to explore its causes and treatments to better support those living with this challenging condition.

High blood pressure (BP) has become a public health problem that is driving cardiovascular diseases like heart attacks and strokes globally. While medications are important to keep hypertension under control, lifestyle changes and healthy practices are also crucial.

Several global health guidelines recommend regular physical activity, but adhering to exercise programs daily becomes a challenge for many people. But in the overtly busy schedules, sparing 10 minutes for an exercise regimen can be easier than travelling to the gym.

A large randomized clinical trial, published in the Journal of the American College of Cardiology (JACC), has proved that a traditional Chinese mind-body practice — baduanjin — may help lower blood pressure, that too, without any equipment.

Baduanjin is a slow, structured movement, focused on deep breathing and meditation.

Importantly, the clinical trial proved that the ancient Chinese technique could lower BP as effectively as brisk walking.

In people practicing baduanjin, BP reductions were seen after three months and were sustained for one year.

"Given its simplicity, safety, and ease with which one can maintain long-term adherence, baduanjin can be implemented as an effective, accessible, and scalable lifestyle intervention for individuals trying to reduce their blood pressure," said Jing Li, Director, National Center for Cardiovascular Diseases in Beijing, China.

Baduanjin: The 10 Minute Routine

Baduanjin is a standardized eight-movement sequence that integrates aerobic, isometric, flexibility, and mind-body components.

It has been in practice for centuries and commonly performed in community settings across China. The routine typically takes 10–15 minutes and requires no equipment and only minimal initial instruction.

Because it is low- to moderate-intensity, it is considered safe and accessible for many adults.

Also read: Cardiovascular Diseases Lead As India’s Top Killer: US Cardiologist Points Out Risk Factors

The Clinical Trial

A team of Chinese researchers led the first large, multicenter randomized trial to look at the impact of baduanjin on blood pressure.

They followed 216 participants, aged 40 years or older, across seven communities to determine changes in 24-hour systolic BP from baseline to 12 and 52 weeks.

Compared to people indulging in self-directed exercise, practicing baduanjin five days a week reduced

• systolic blood pressure by approximately 3 mg Hg
• systolic blood pressure by 5 mg Hg.

Notably, the benefits were sustained even without ongoing monitoring, a key challenge for many lifestyle interventions that struggle to maintain long-term adherence outside structured programs.

"Baduanjin has been practiced in China for over 800 years, and this study demonstrates how ancient, accessible, low-cost

approaches can be validated through high-quality randomized research," said Harlan M. Krumholz, Editor-in-Chief of JACC and the Harold H. Hines, Jr Professor at the Yale School of Medicine.

"The blood pressure effect size is similar to that seen in landmark drug trials, but achieved without medication, cost, or side effects. This makes it highly scalable for community-based prevention, including in resource-limited settings," they added.

Also read: AHA Cholesterol Guidelines 2026: How Indians Can Improve Heart Health

How To Practice Baduanjin

• Stand upright with your feet shoulder-width apart and keep your movements slow and controlled.
• Coordinate each motion with steady, deep breathing, inhaling and exhaling smoothly as you move.
• Move through the traditional eight postures in sequence, focusing on posture, balance, and relaxation rather than speed or force.
• Practice for about 10 to 15 minutes a day in a quiet space, maintaining calm attention throughout.

Are you a working professional? Have you been diagnosed with endometriosis? Worried about how this condition can impact your career? Well, don’t panic! We give you vital tips to manage the symptoms of endometriosis without compromising your professional aspirations. Dr. Kanika Gera Thakral, Consultant – Obstetrics & Gynaecology, Motherhood Hospitals, Greater Noida, spoke about the effects of endometriosis on working women and what women can do to not let the pain take a toll on their work life.

What is endometriosis?

Endometriosis happens when tissue similar to the lining of the uterus grows outside the uterus. These tissues commonly develop on the ovaries, fallopian tubes, or the pelvic lining. Endometriosis affects many women and can impact their daily lives, including their ability to work comfortably. Many women continue their professional responsibilities despite experiencing severe discomfort, fatigue, and pain.

Raising awareness about the condition and encouraging supportive workplaces can help women manage both their health and career more effectively. Since it is a progressive disorder, timely intervention remains key to managing it. In many cases, women live with symptoms for several years before receiving the correct diagnosis, which can delay treatment and affect their quality of life.

Read more: The Right Approach To Manage Endometriosis

The workplace challenge

Many working women who are diagnosed with endometriosis tend to experience symptoms such as pelvic pain, cramps, fatigue, nausea, and heavy menstrual cycles. These symptoms can make it difficult to maintain productivity at work, especially during flare-ups. Hence, women will be unable to concentrate on work or finish the tasks. Some may miss deadlines and meetings due to the painful symptoms. Women will have to skip going to work when the symptoms are intense and will have to rest at home. So, women living with endometriosis may face interruptions in their career growth and reduced working hours. But don’t worry, it is possible to manage this condition and give your best at work.

1. Long working hours, prolonged sitting, workplace stress, irregular meals, and lack of adequate rest can sometimes worsen symptoms of endometriosis.
2. Apart from physical discomfort, the condition can also affect emotional well-being. Living with chronic pain may lead to stress, anxiety, or frustration, which can indirectly impact workplace confidence and productivity.

Strategies for managing work and endometriosis

It is necessary for women with endometriosis to go for regular check-ups and follow-ups with the doctor. Women can continue to pursue their professional goals by adopting practical strategies to manage the condition. Open communication with employers when it comes to flexible schedules can help overcome stress and anxiety. Women should have access to remote working to avoid unnecessary travel due to pain.

The work-from-home option can be given to the women when needed by them. Planning demanding tasks during times of higher energy and maintaining a balanced daily routine can also improve productivity at work. Women should make sure to keep essential medications, a heating pad, or comfort aids at their desk to be able to relieve sudden discomfort. Likewise, using ergonomic seating or maintaining good posture while working may reduce pelvic and even back discomfort. Women should also connect to support groups that help to provide emotional reassurance and useful coping strategies that include yoga and meditation.

Lifestyle habits also play an important role. Regular physical activity, adequate sleep, stress-management techniques such as yoga or meditation, and following an anti-inflammatory diet rich in fruits, vegetables, whole grains, and healthy fats may help reduce flare-ups.

Read more: Women With Endometriosis Are Earning Less, Reveals Study

Treating endometriosis

Treatment is particularly based on the severity of symptoms. Women will be advised lifestyle modifications such as regular exercise, stress management, and an anti-inflammatory diet. Non-steroidal anti-inflammatory drugs may help reduce discomfort. Hormonal therapies may also be used to control symptoms. Some women will be advised to undergo laparoscopy to remove endometriotic cysts. Minimally invasive surgery can help remove lesions and restore pelvic anatomy, which may also improve fertility in some cases. In advanced cases, surgery can be recommended to women.

With timely care and supportive workplaces, women can pursue their ambitions without letting endometriosis interfere with their careers.

Four years after suffering from a rare neurological condition known as Stiff-Person Syndrome, Céline Dion, known for power ballads like My Heart Will Go On and Because You Loved Me, has announced her return to the stage.

The incurable condition had affected her singing voice and even her ability to walk.

In a message on her Instagram page, the singer announced plans to play a 10-night residency at the 40,000-capacity Paris La Défense Arena in September and October.

Calling her comeback "the best gift of my life", 58-year-old Dion said: "I'm doing great, managing my health, feeling good. I'm singing again, even doing a little bit of dancing.

"I'm so ready to do this. I'm feeling good, I'm strong, I'm feeling excited, obviously, [and] of course, a little nervous," she said, while thanking her fans for the “prayers and support, kindness and love”.

What Is Stiff Person Syndrome

Stiff-Person Syndrome is a neurological disease caused by the signals from the nerves to the muscles not working properly. It affects an estimated 8,000 people worldwide.

It is also an autoimmune is a neurological disease caused by the signals from the nerves to the muscles not working properly. It affects an estimated 8,000 people worldwide.

It is also an autoimmune condition, that is linked to diseases such as type 1 diabetes, thyroiditis, vitiligo, and pernicious anemia.

For some, it can be debilitating. SPS is progressive, meaning it gets worse over time. There is no known cure.

Common symptoms may include:

• Stiff muscles in the torso, arms, and legs
• Greater sensitivity to noise, touch, and emotional distress, which can set off muscle spasms

The condition is also more common among women than men, and affects people between the ages of 20 and 60.

While there is no known cure for SPS, current treatments such as intravenous immunoglobulin (IVIg) can help manage the symptoms.

Stiff-Person Syndrome: Celine Dion’s Diagnosis

Dion announced her diagnosed with Stiff Person Syndrome (SPS) in December 2022 in an emotional Instagram video. The condition had affected "every aspect of my daily life", she told her fans.

The best-selling artists of all time began noticing her symptoms, such as feeling "a little spasm" while performing on stage. She found her “voice was struggling", BBC reported.

Even though she experimented with her singing to ease the stress on her vocal cords, her condition worsened. She also began facing difficulties while walking.

"It's like somebody is strangling you. It's like somebody is pushing your larynx [or] pharynx," she told NBC News.

Determined to get back on her feet and sing, worked "all my body and soul, from head to toe, with a medical team", French Vogue magazine reported.

"Five days a week, I undergo athletic, physical, and vocal therapy. I work on my toes, my knees, my calves, my fingers, my singing, my voice."

The intense workouts enabled her to make a comeback at the 2024 Paris Olympics, singing Edith Piaf's classic Hymne à l'Amour from the Eiffel Tower.