Diabetes insipidus (DI) is a rare medical condition that disrupts the body's ability to regulate water, resulting in excessive thirst and an unusually high volume of urine. This condition affects the kidneys' ability to concentrate urine and causes individuals to produce between 3 and 20 quarts of dilute, colourless urine daily, compared to an average of 1 to 2 quarts. It is pertinent to note that DI is not related to diabetes mellitus, which disrupts the body's insulin production.

Types Of Diabetes Insipidus

This condition results from damage to the hypothalamus or pituitary gland, which impairs the production or release of vasopressin, a hormone responsible for water retention. When vasopressin levels are inadequate, the kidneys fail to conserve water, leading to excessive urination. It can result from Brain injuries or surgeries, tumours, infections or inflammation and aneurysms.

Nephrogenic Diabetes Insipidus

This type occurs when the kidneys fail to respond to vasopressin, causing excessive fluid loss. Common triggers include chronic kidney disease, and electrolyte imbalances, such as high calcium or low potassium levels. Additionally, medications like lithium

and urinary tract blockages can also cause Nephrogenic DI.

Gestational Diabetes Insipidus

A rare condition seen only during pregnancy, this occurs when the placenta produces an enzyme that breaks down vasopressin or increases prostaglandin levels, reducing kidney sensitivity to the hormone. Symptoms of this are usually mild and often resolve postpartum but can recur in future pregnancies.

Symptoms And Warning Signs

• Severe thirst, often leading to the consumption of over a gallon of water daily
• Frequent urination (polyuria), sometimes exceeding 20 quarts per day
• Nighttime urination and bed-wetting
• Weakness, muscle pain, and preference for cold drinks

In severe cases, dehydration may develop, manifesting as fatigue, dizziness, dry mouth, confusion, nausea, or fainting. Infants and children with DI may exhibit crankiness, poor feeding, slow growth, fever, or vomiting.

Causes And Risk Factors

DI stems from issues with vasopressin production or response. Central DI arises from damage to brain structures, while nephrogenic DI relates to kidney dysfunction. Risk factors include:

- Genetic mutations affecting water regulation

- Certain medications like diuretics or lithium

- Metabolic disorders that alter calcium or potassium levels

- Brain injuries or surgeries

Diagnosis And Testing

Diagnosing DI involves a combination of medical history, physical exams, and specialized tests:

- Urinalysis: Evaluates urine concentration and glucose levels to distinguish DI from diabetes mellitus.

- Blood tests: Check electrolyte, glucose, and vasopressin levels.

- Water deprivation test: Measures changes in weight, blood sodium, and urine concentration during fluid restriction.

- MRI: Detects abnormalities in the hypothalamus or pituitary gland.

- Genetic screening: Identifies inherited risk factors.

Although DI is rare, affecting about 1 in 25,000 people, early diagnosis and targeted treatment can significantly improve quality of life. Researchers continue to explore its causes and treatments to better support those living with this challenging condition.

The southern Indian state of Karnataka, currently reeling under intense summer heat, has been experiencing an outbreak of viral gastroenteritis over the past few weeks, according to media reports.

Due to the scorching heat, doctors in Mysuru flagged a 15-20 per cent rise in patients with gastrointestinal complaints, Deccan Herald reported.

According to Dr A. K. Satheesh Rao, senior consultant in medical gastroenterology and hepatology, the early arrival of summer with higher intensity across Mysuru and surrounding regions is driving the cases.

“The prolonged spells of heat and rising temperatures are impacting stomach and digestive health. Over the past few weeks, we have seen about a 15-20 per cent increase in patients with gastrointestinal complaints like frequent episodes of vomiting, abdominal discomfort, rapid dehydration, and diarrhea. Another major concern is a rise in dehydration,” he said.

“Although such seasonal spikes are expected, this year the intensity and frequency of symptoms are concerning, as a majority of the cases are being diagnosed as viral gastroenteritis. Just like any other viral infection, viral gastroenteritis is transmissible through contaminated food and water,” Dr. Rao added.

Meanwhile, the India Meteorological Department (IMD) has issued a warning of rising heat and humidity across Coastal Karnataka until April 12.

Districts like Dakshina Kannada, Udupi, and Uttara Kannada are expected to experience hot weather with high atmospheric moisture. Such weather can lead to fatigue and discomfort, particularly among the elderly, children, and those with existing health conditions.

The IMD has advised people to stay well hydrated and take precautions while stepping outdoors. Residents are also urged to avoid prolonged exposure to the sun during peak hours.

What Is Gastroenteritis?

Commonly referred to as the stomach flu, gastroenteritis is another illness that tends to spike in the fall.

Caused by viruses like norovirus, this condition leads to inflammation of the stomach and intestines. While gastroenteritis is typically short-lived, it can be particularly uncomfortable and disruptive.

Common symptoms include:

• Nausea and vomiting – More common in children than adults.
• Watery diarrhea – May cause dehydration if not well taken care of.
• Stomach cramps and pain – Usually intense and sudden.
• Mild fever and body aches – May be confused with flu.
• Sudden development of illness – Symptoms develop 24-48 hours after exposure and persist 1-3 days.

Gastroenteritis can affect children more intensely. Dehydration is the most immediate threat posed by stomach flu, particularly among infants and young children. As children quickly lose fluids from diarrhea and vomiting, parents must observe warning symptoms of severe dehydration, such as:

• Dry mouth and tongue
• Decreased urine output (fewer wet diapers in an infant)
• Not crying tears
• Sunken soft spot on the top of a baby's head (fontanelle)
• Irritability, drowsiness, or lethargy.

How To Prevent

Hydrating oneself with portable water, eating healthy food, and maintaining hand hygiene are important.

“Simple practices like proper water storage, drinking filtered or boiled and cooled water, opting for home-cooked and freshly prepared meals, and basic hand hygiene serve as powerful safeguards,” Dr Rao said.

Further, one should also follow essential hygiene practices, including:

1. Practice frequent handwashing

2. Clean high-touch surfaces

3. Safe food handling

4. Keep sick children at home.

There are many myths linked to heart health that can mislead people and prevent them from seeking timely help. This article helps to debunk the myths and keep the heart healthy. It is time to prioritize heart health. Dr Rahul Gupta, Director of Interventional Cardiology and Structural Heart Program, Gleneagles Hospital, Parel, Mumbai, spoke about the common myths about heart disease and listed the facts as well.

Heart problems are commonly seen in people of all age groups. However, heart health is often surrounded by myths and misconceptions that can lead to confusion and poor lifestyle choices in people. So, heart health depends on multiple factors, including diet, activity, stress, and overall lifestyle, and not just one or two habits. Here, the expert helps to debunk the myths associated with heart health and improve the quality of life.

Dispelling myths surrounding heart health

Myth 1: Only older people are at risk of heart problems

Fact: People commonly believe that heart problems can only happen in old age. However, currently, a large number of youngsters aged 25-35 are also struggling with heart issues such as heart attacks and heart failure because of stress, unhealthy diets, and lack of exercise. So, heart problems are not limited only to older people. Anyone, irrespective of their age, can suffer from them. Hence, there is a need of the hour to go for regular heart check-ups and to initiate timely treatment for heart problems.

Myth 2: If you are fit, your heart is SAFE

Fact: So, being physically active is important, but it does not reduce the chances of heart problems. Be attentive to the family history, genetics, and other factors such as high cholesterol or even stress. So, go for cardiac screening on a yearly basis to know the status of your heart health. Discomfort in the arms, jaw, or back and light-headedness can also mean that your heart is in danger.

Myth 3: Heart disease is only seen in men

Fact: Shockingly, heart disease also causes higher morbidity and mortality rates in women. The symptoms seen in women linked to heart disease are dizziness, palpitations, and even giddiness. Hence, women should also focus on their heart health. Stay alert, stay safe!

Your heart health matters. By understanding the facts and making informed choices, it is possible for everyone to protect their heart and overall well-being.

Parkinson's disease is a condition that affects people with Parkinson's ability to move and do things on their own. People with Parkinson's disease will find that it gets worse over time. At first, medicines can help people with Parkinson's disease.

After a while, these medicines might not work as well as they used to for people with Parkinson's disease. Some people with Parkinson's disease might even feel bad because of the medicines they are taking for Parkinson's disease.

That is when doctors might suggest something called Deep Brain Stimulation, or DBS for short, to people with Parkinson's disease. Deep Brain Stimulation is a kind of help for people with Parkinson's disease.

What Is DBS?

DBS is a kind of surgery where doctors put wires into the brain. These wires are connected to a device that is put under the skin in the chest. This device sends messages to the brain to help it work better. The brain can get mixed up. Cause people to shake or move slowly. The messages from the device help fix that.

One of the things about DBS is that it can help people move better when medicines are not working well. People might shake less. Feel less stiff. They might even be able to take medicine, which can be good because it can reduce the side effects.

It is very important to remember that DBS is not a cure for Parkinson's disease. It does not make the disease go away. It can help people do things on their own again. Many people who have DBS say they can eat, walk, and dress themselves better. These are things that can be very hard for people with Parkinson's disease.

DBS Promising For Parkinson's Patients

Doctors have to be very careful about whom they recommend DBS to. It is usually for people who take medicines for Parkinson's disease. The medicines do not always work well. The doctors, surgeons, and therapists all have to work to make sure everything goes well.

Exciting things are happening with DBS. Soon, there might be devices that can adjust on their own to help people more. This means that people with Parkinson's disease might have more hope for feeling better.

DBS is a step forward from just taking medicines. It helps people take control of their bodies again. It helps them feel more independent and dignified. That can make a difference in their daily lives. Parkinson's disease is a hard condition to deal with, but with DBS, people might feel like they can do things again. They might feel like they have their life back. DBS is a promising treatment for people with Parkinson's disease.