Overview

This is a disease that is transmitted from mosquitoes to humans and affects many people in the world. Found in densely populated countries and continents, like Africa, Asia and the tropics of the Americas, this has severe symptoms. This viral disease is caused by the Chikungunya virus of the Togaviridae. First identified in the United Republic of Tanzania in 1952 and subsequently in other countries like Africa and Asia. Since 2004 the outbreak of CHIKV virus has become more widespread and caused partly due to the viral adaptations allowing the virus to be spread more easily by Aedes albopictus mosquitoes. The transmission has been noted to persist in countries where there is a large population, but interestingly, the transmission has been interrupted on islands where a high proportion of the population is infected and then immune.

Symptoms

The onset of the disease is usually in 4-8 days and after a bite of an infected mosquitoes, it is characterized by an abrupt onset of fever and then joint pain. This joint pain is severed and lasts for a few days but may prolong for months maybe even years. Other signs are joint swelling, muscle pains, headache, nausea, fatigue and rash. These symptoms also overlap with those of dengue and Zika virus and can be misdiagnosed. Most people fully recover from the infection and experience only mild and sometimes the infection even goes unrecognized. However, there have been cases of eye, heart, and neurological complications. The elderly and newborns are more susceptible to the infection and if they have any underlying conditions then they are likely to become severely ill increasing the risk of death.

Diagnosis and treatment

The diagnosis and treatment of the virus may be done by blood sampling and other tests like reverse transcriptase–polymerase chain reaction (RT–PCR). Other tests detect the activity of the antibodies. These can be detected in the first week after illness onset and can be detected for about 2 months. Many clinical measures can be taken to address fever and joint pain. But there is no specific anti-viral drug treatment for the virus.

Preventing Chikungunya

As this disease is caused by the bite of a mosquito, you must reduce the opportunities to let the mosquito breed. Mosquitoes bite during the day and night, and for people who live in risk areas like southeast Asia, Africa and tropical regions of America, many outbreaks happen each year. The best way to prevent it is to protect yourself from the mosquito's bite. You also must get vaccinated before travelling to any of these regions. Use insect repellent, and wear long-sleeved shirts and pants. You can also treat your clothes and gear with permethrin. As we all know, they tend to breed in humid places and places where they have access to water, so try to close the rooms that are air-conditioned with screens and windows. Use nets and mosquito repellents if you are sleeping outside. There are many different types of mosquito repellents like paper, liquid etc, and they are quite effective. If your job needs, you to be stationary for long hours or frequently go outside you must take the necessary precautions.

A team of UK scientists has developed a non-invasive brush biopsy test that can detect oral cancer within just 60 minutes, potentially transforming the way the disease is diagnosed.

Researchers from Queen Mary University of London say the test could prevent more than 90% of unnecessary scalpel biopsies, reducing pain, infection risk and diagnostic delays. The findings were published in the journal Biomarker Research.

Early diagnosis of oral squamous cell carcinoma (OSCC) is critical. However, most oral potentially malignant disorders (OPMDs) are benign, meaning many patients undergo invasive scalpel biopsies that ultimately show no cancer.

These procedures can be painful, carry a risk of infection and, in areas such as the gums, can be difficult to perform and may damage the underlying tooth or bone.

Beyond diagnosis, researchers say the test could also help monitor patients with persistent OPMDs over time. Because the test is non-invasive and repeatable, it can be used for regular surveillance, improving the chances of detecting malignant transformation at an early stage, when treatment is most likely to be successful.

How Does The Brush Test Work?

The newly developed brush biopsy requires only a simple swab of the mouth, without removing any tissue. According to the researchers, the test can identify low-risk patients and potentially spare more than 90% of them from unnecessary invasive tissue biopsies. Another advantage is speed—the results are available within one hour.

"This test gives clinicians a rapid, accurate, and non-invasive way to triage patients, and crucially, it can be repeated. That means we can now monitor patients with persistent pre-malignant lesions regularly and systematically — and pick up cancers much earlier than we would have been able to before," said Muy-Teck Teh, Professor of Molecular Oral Oncology at Queen Mary.

How Was The Study Conducted?

The study is the largest of its kind, involving more than 1,000 samples from 545 patients. The team collected brush biopsies from the mouths of 545 patients with lesions that could potentially be cancerous.

The test was found to have an overall accuracy of 95.5 percent, with false-positive and false-negative rates of less than 5 percent. The results were available within an hour.

The latest study builds on an earlier version of the test, qMIDS-V2, which required a 1 mm microbiopsy and had already been validated using more than 530 samples from the UK, India and China.

The new qMIDS-V3 requires only a brush swab of the mouth, with no tissue removal, yet achieves test performance comparable to its microbiopsy predecessor.

Oral Cancer Remains A Growing Global Burden

According to Global Burden of Disease data, lip and oral cancer are among the world's fastest-growing causes of early death.

More than 10,000 people in the UK were diagnosed with oral cancer last year, while 3,637 people died from the disease, according to the charity Mouth Cancer.

Worldwide, oral cancer affects around 650,000 people every year. Major risk factors include tobacco use, smoking, alcohol, HPV infection and sun damage. More than 53% of mouth cancers are diagnosed at Stage IV, when the disease is at its most advanced.

What does it take to become a CEO? Decades of hustle and hard work. J Michael Prince, CEO of US Polo Assn., probably had the same idea. But after years of toiling away, he landed at a startling realization – he could have done it all without pushing himself to the limit. He recently opened up about the importance of work-life balance and setting aside time for yourself at the end of the day.

Work-Life Balance And Burnout

In a conversation with Fortune, Prince said that he now makes a conscious effort to avoid contacting his employees outside office hours unless it’s an emergency.

He said, “One thing I try to respect is—and this never really happened to me throughout my career—unless there’s something major going on, I try to leave people alone in the evenings, so you rarely ever get an email or text from me after the office.”

He spoke about the importance of personal time and allowing oneself to reset after a workday. “I leave the office, and I really try to respect people’s weekends, because I feel like that’s your family time, that’s your personal time, that’s your friendship time, that’s your time to reset, recharge spiritually, mentally, physically, emotionally,” he added.

HealthandMe spoke to Dr. Samant Darshi, Consultant- Psychiatrist & Neuromodulation Expert, Director - Psymate Healthcare, Noida, about the importance of maintaining work-life balance to prevent burnout.

Read more: Doctors Day: From Burnout To Work Anxiety, The Mental Health Struggle Doctors Rarely Talk About

The expert says that it is necessary to maintain a balance between work and life since it helps in enhancing health and well-being, reduces stress, increases productivity, and develops meaningful relationships. Maintaining a balance would lead to higher job satisfaction and happiness in life.

Dr Darshi says, “Work-life imbalance increases levels of stress and anxiety and causes emotional exhaustion. Persistent stress can result in depression, insomnia, hypertension, decreased immunity, and cardiovascular diseases. Lack of rest and time for leisure activities causes a loss of concentration and low self-esteem, thus making everyday life more stressful and challenging.”

Tackling Burnout

Prince admitted he didn’t always give importance to work-life balance. Earlier in his career, he regularly worked 90-hour weeks, stayed up through the night, and rarely slowed down. Looking back, he said he could have achieved the same goals without sacrificing so much of his health and time.

Prince said, “I could have eaten differently, I could have been a little more thoughtful about my sleep, about my routine around working out, my travel.”

According to Dr Darshi, work-life imbalance leads to a feeling of burnout. Experiencing constant stress, unrealistic expectations, and lack of time for leisure gradually exhausts physical and emotional resources. Eventually, motivation tanks, productivity drops, fatigue, detachment, frustration, and inability to function increase.

He explains, “Burnout adversely impacts the mental state of an individual by causing symptoms such as emotional fatigue, anxiety, depression, irritability, and hopelessness. It causes demotivation and loss of focus in addition to making individuals feel insecure. If not addressed, it may adversely impact personal relationships, affect work, and cause chronic health conditions.”

While many people blame pollen or changing weather for their allergies, health experts say hidden allergens inside the home may be just as responsible. On the occasion of World Allergy Day on July 8, doctors highlighted that dust mites, mold, pet proteins, and household products are among the often-overlooked triggers that can affect indoor air quality and contribute to persistent allergy symptoms.

They also cautioned that chronic allergies should not be dismissed as a minor inconvenience, as they can affect sleep, respiratory health, and overall quality of life.

What Is A Chronic Allergy?

Dr. Sanjiv Dang, ENT & Allergy Specialist, Apollo Hospitals, Delhi, told HealthandMe that allergy symptoms lasting for weeks, months, or throughout the year may indicate chronic allergies and should not be ignored.

He explained that "allergies occur when the immune system overreacts to substances such as dust mites, pollen, mold, pet dander, or certain foods, releasing histamine". This can lead to symptoms including sneezing, nasal congestion, a runny nose, itchy eyes, and throat irritation.

Hidden Allergens Go Beyond Pollen

Also read: UK Met Office Warns of 'Pollen Bomb': What Hay Fever Patients Need to Know

Prof. (Dr.) Dwaipayan Mukherjee, Consultant ENT Surgeon, Kolkata, told HealthandMe that flower pollen is often blamed for seasonal allergies, but it is usually not the main culprit because its grains are larger and less likely to remain airborne. Instead, he said most seasonal allergies are caused by microscopic airborne pollen from grasses, weeds, and trees.

Dr. Mukherjee, also the Past President of the Association of Otolaryngologists of India (AOI), added that homes can also harbor numerous microscopic allergens that negatively affect indoor air quality. Common triggers include:

• Dust Mites

• Mold

• Pet Proteins

Household Products and Indoor Plants

Cleaning sprays, air fresheners, scented candles, and similar products may emit compounds that irritate sensitive airways and worsen allergy symptoms despite creating the impression of a cleaner environment.

Indoor plants can also become a source of allergens if mold develops in damp potting soil or if certain plants release pollen. Outdoor pollen from trees, grasses, and weeds can also enter homes on clothing, shoes, and hair before settling on indoor surfaces, the experts said.

How Persistent Allergies Affect Health

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Dr. Dang said chronic allergies are more than just a runny nose. Persistent nasal congestion can disrupt sleep, leading to snoring, frequent awakenings, daytime fatigue, poor concentration, reduced productivity, and mood changes.

He added that ongoing allergic inflammation can affect both the upper and lower airways. People with chronic allergies are at a higher risk of developing asthma, while those who already have asthma may experience worsening symptoms such as coughing, wheezing, chest tightness, and shortness of breath.

Chronic allergies can also block normal sinus drainage, increasing the risk of recurrent sinus infections. Facial pressure, headaches, post-nasal drip, persistent congestion, and a reduced sense of smell may all indicate allergy-related sinus problems.

How To Prevent Chronic Allergies

The experts advised relying solely on over-the-counter medications, saying they may provide temporary relief without addressing the underlying cause. They noted that prolonged use of certain nasal decongestant sprays can even worsen congestion over time, and also recommended consulting a healthcare professional if allergy symptoms persist for several weeks or throughout the year.

To help manage chronic allergies, the experts recommended:

• Improving ventilation indoors.

• Controlling indoor humidity.

• Using HEPA air cleaners.

• Cleaning the home regularly.

• Eliminate excess moisture.

• Identifying and reducing exposure to allergy triggers.

• Controlling mold growth indoors.