Blue Light (Credit: Canva)
Blue light emitted by devices like smartphones, computers, and televisions is becoming a major factor disrupting our sleep cycles. Research reveals that a significant number of Americans use electronic devices close to bedtime, contributing to poor sleep quality. Reducing exposure to blue light, particularly in the evening, is a simple yet effective way to help your body prepare for restful sleep.
Circadian rhythms are 24-hour cycles that control essential bodily functions, including sleep. Light is the primary factor that aligns these rhythms with day and night. Historically, exposure to sunlight during the day helped set our body clocks, signaling when to be awake and when to sleep. However, the widespread use of artificial lighting and electronic devices has introduced more light exposure after dark, disrupting these natural cycles.
Blue light, in particular, has the strongest impact on circadian rhythms. During daylight hours, blue light helps us feel alert by stimulating the brain, raising body temperature, and increasing heart rate. But in the evening, exposure to blue light can confuse the body’s internal clock, suppressing melatonin—the hormone responsible for making us feel sleepy. As a result, our brains may remain in “daytime mode,” preventing us from winding down for the night.
Persistent disruption of circadian rhythms can lead to a range of health issues, including metabolic disorders, poor mental health, and increased risk for conditions like depression and anxiety. Furthermore, the inability to sleep well at night affects cognitive performance, mood, and overall well-being. Chronic exposure to blue light in the evening may significantly contribute to these negative health outcomes.
Many common devices in our daily lives emit blue light, including:
- Smartphones and tablets
- Computer monitors and laptops
- Televisions and e-readers
- LED and fluorescent lighting
- Video game consoles
To reduce the effects of blue light on your sleep, here are some practical strategies:
1. Turn off screens before bed: Try to avoid using electronic devices at least two to three hours before bedtime. Reducing screen time helps prevent blue light from interfering with melatonin production.
2. Adjust your lighting: Dim your home’s lights or switch to warmer-toned lighting in the evening. You can also use lamps with red or orange light, which are less likely to impact your circadian rhythms.
3. Night mode settings: Many smartphones and computers have a "night mode" feature that reduces blue light emission. Make use of these features to limit exposure in the hours leading up to bedtime.
4. Blue light-blocking glasses: Special glasses designed to filter out blue light may be helpful for some individuals. These glasses can block or reduce the melatonin-suppressing effects of blue light.
5. Apps for blue light reduction: There are several smartphone and computer apps available that reduce blue light emission, allowing you to use your devices before bed without disturbing your sleep.
6. Create a sleep-friendly environment: If you can’t control light sources in your bedroom, consider using an eye mask to block out ambient light and promote better sleep.
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Alzheimer’s disease and dementia are often viewed as diseases of old age, with memory loss considered one of their most recognizable symptoms. However, emerging research increasingly points to factors such as diabetes, blood pressure, hormonal changes and lifestyle during midlife, particularly from the 40s onward, that may influence the risk of cognitive decline later in life.
As ageing populations worldwide face a growing dementia burden, doctors are emphasizing the importance of identifying and addressing these risks in midlife. Alzheimer’s disease is a progressive brain disorder that affects memory, thinking and the ability to manage everyday life.
HealthandMe spoke to doctors about the disproportionate burden of Alzheimer’s among women, the link between diabetes and accelerated brain ageing, and how disease-modifying treatments such as lecanemab are changing the treatment landscape. They also highlighted the importance of early assessment to identify cognitive problems that families may otherwise dismiss as normal ageing.
Type 2 diabetes is an important modifiable factor associated with accelerated brain ageing, making cognitive health an important part of diabetes care.
Dr. V. Mohan, Managing Director, Dr Mohan’s Diabetes Specialities Centre and President, Madras Diabetes Research Foundation, told HealthandMe that every diabetes appointment follows a familiar rhythm: check blood sugar, examine the feet, check the eyes, review the heart and kidneys, and renew the prescription. But the brain, more often than not, receives little attention.
Research suggests that type 2 diabetes is associated with accelerated brain ageing, while vascular damage linked to high blood sugar, blood pressure and cholesterol can affect the brain as well as the heart, kidneys and eyes.
The 2024 Lancet Commission on dementia prevention, intervention and care identified diabetes as one of 14 modifiable risk factors associated with nearly half of dementia cases worldwide.
“The message is simple: just as people routinely check their blood pressure, blood sugar, eyes, feet and kidneys, cognitive health deserves attention too,” he said, while suggesting ABCD for Protecting Brain Health in Diabetes:
A – Aim for HbA1c Control
B – Blood Pressure Control
C – Control Cholesterol
D – Diet Management
Read More: Hormone Replacement Therapy May Lower Dementia Risk In Women, Shows Study
Women carry a disproportionate burden of Alzheimer’s disease. According to Stanford, roughly three women are diagnosed with Alzheimer’s for every two men, while data from the Framingham Heart Study cited by the
Alzheimer’s Association estimated that at age 45, the lifetime risk of developing clinical Alzheimer’s dementia was about 20% for women compared with 10% for men.
Dr. Anmol Singh Rai, Consultant Neurology, Fortis Hospital Jalandhar, pointed out several factors that may contribute to this difference. He noted:
“Managing blood pressure, blood sugar and cholesterol, addressing hearing loss, identifying sleep apnea, staying physically active and addressing depression and social isolation can all form part of a broader approach to brain health,” he told HealthandMe.
More than 55 million people worldwide live with dementia today, with a new case developing every three seconds. This number is projected to rise to 139 million by 2050.
With the arrival of disease-modifying treatments such as Leqembi (lecanemab), the importance of identifying cognitive decline early has become even greater.
"For three decades, Alzheimer's treatment has leaned on drugs that modestly improve cognition, function and behavior, buying patients and caregivers meaningful time. But none of them alter the underlying biology of the disease," Dr. Praveen Gupta, Chairman, Marengo Asia International Institute for Neuro and Spine (MAIINS), Marengo Asia Hospitals, Gurugram, told HealthandMe.
The disease-modifying therapy for Alzheimer’s, Leqembi, was cleared in the US in 2023, followed by Japan the same year, China in June 2024, the European Union in 2025, and India in August 2026.
"Unlike everything that came before it, lecanemab is designed to act on the pathological process itself, not merely its downstream consequences," Dr. Praveen Gupta said.
However, the treatment is not meant for everyone with Alzheimer’s. It is approved for early Alzheimer’s disease, including mild cognitive impairment and mild dementia, rather than moderate or advanced disease.
That makes timely diagnosis particularly important.
"Patient selection now hinges on confirming amyloid pathology, through cerebrospinal fluid analysis or blood-based biomarkers, before treatment even begins," Dr. Praveen Gupta explained.
The experts noted that brain health is not something that needs attention only after memory loss begins.
Midlife is an important window to control blood pressure, blood sugar and cholesterol, remain physically active, address hearing and sleep problems, and pay attention to changes in memory or thinking.
For people already showing cognitive symptoms, early medical assessment can help distinguish normal ageing from mild cognitive impairment, dementia or potentially treatable conditions.
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Cardiac arrest is considered one of the most urgent medical situations. It can occur unpredictably, at home, at work, while traveling, or anywhere. It is characterized by a blockage in the heart's arteries, and it differs from a heart attack, which is a situation when the heart stops pumping blood into the body. After a few minutes, oxygen deficiency happens and affects the brain and other organs. Therefore, it is important to know how to perform cardiopulmonary resuscitation (CPR).
CPR is an emergency lifesaving technique that uses chest compressions and, in some situations, blowing mouth-to-mouth air into the person who has suffered a cardiac arrest, to help maintain blood circulation and oxygen delivery to vital organs when a person's heart has stopped beating effectively. It does not restart the heart by itself, but it can keep blood flowing until an automated external defibrillator (AED) is available or emergency medical professionals arrive.
Importantly, CPR is not a skill limited to doctors or healthcare professionals. It can be administered by ordinary people for whom learning the basic CPR techniques is easy.
If someone faces cardiac arrest, rapid actions may save this person's life. If CPR is performed directly and immediately after a cardiac arrest, it will be possible to keep the flow of blood to the brain and other organs before the arrival of medical experts. The use of CPR can improve the chances of survival for patients who have experienced cardiac arrest.
Besides, in combination with early defibrillation through an AED, it can be even more effective. AED is a portable medical device that checks the heart rhythm of the person experiencing cardiac arrest and delivers an electric shock to restart a normal heartbeat.
However, sometimes people prefer to do nothing for fear of mistakes. But it is much more dangerous not to act at all.
It begins with identifying the presence of a possible cardiac arrest in the patient. The patient will generally fall, become unconscious, and will not breathe properly. They can occasionally breathe abnormally with strange sounds, which should not be considered breathing properly.
If you see anyone fall and become unresponsive, check whether they respond to your questions and breathe normally. Tell any passerby to call the emergency services and bring an AED device, if one is present. If the patient is not breathing normally, initiate CPR on them.
If the patient is an adult, hands-only CPR can be done easily by everyone. For this, you need to keep the heel of one of your hands in the center of the person’s chest, keep your other hand over it, and press down with a rapid rhythm. The compression must be continued at a pace of around 100-120 beats per minute.
Also, you can use the AED device if one is available. Turn on the AED and follow the steps according to the voice prompts from it. The AED device will analyze the rhythm of the heart and give a shock.
Another reason for reluctance to administer CPR is the notion that it should be administered only by doctors, nurses, and other professionals. However, even basic CPR can be taught to regular citizens using special courses. It takes only a couple of hours of practice for someone to gain enough confidence to use CPR in emergencies.
CPR training should be more accessible in schools, offices, and residential communities, as it would help people know what to do in those critical first few minutes.
Cardiac arrest will not wait for doctors to show up. When cardiac arrest occurs, the first person on the scene might be either a relative, co-worker, friend, or a total stranger. Knowing CPR will prepare you for these moments of life or death. A simple skill learned today may help save someone’s life tomorrow.
(Dr. Lalit Kapoor, Senior Consultant - Cardiac Surgery and Robotic Surgery – Narayana RN Tagore Hospital, Mukundapur, Kolkata)
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Worried about your graying hair? It may reflect a natural cellular response to DNA damage, according to a study by Japanese researchers.
Hair color comes from melanocyte stem cells (McSCs), which live inside hair follicles and produce melanin, the pigment responsible for hair and skin color. These cells are especially sensitive to DNA damage from environmental and internal factors.
While DNA damage is linked to both aging and cancer, researchers at the University of Tokyo found that McSCs can take different paths after being damaged — including one that leads to hair graying and another associated with melanoma, a type of skin cancer.
When McSCs suffer certain types of DNA damage, they can undergo a process called senescence-coupled differentiation, or seno-differentiation. The damaged stem cells permanently differentiate and are eventually lost, leading to hair graying.
This response is driven by the p53–p21 pathway and may help eliminate damaged cells before they can become cancerous.
Also read: Unusually High Cancer-Fighting Immune Cells Could Explain Why Some People Live Beyond 100: Study
Published in Nature Cell Biology, the study examined how McSCs respond to different types of DNA damage.
Professor Emi Nishimura and Assistant Professor Yasuaki Mohri used long-term in vivo lineage tracing and gene-expression profiling in mice to study the fate of these stem cells.
The researchers found that DNA double-strand breaks triggered seno-differentiation. In this process, damaged McSCs irreversibly differentiate and are lost, resulting in hair graying.
However, the response was different when the cells were exposed to certain carcinogens, including 7,12-dimethylbenz(a)anthracene, or ultraviolet B. In these situations, McSCs could bypass the protective differentiation process, retain their ability to self-renew and expand clonally.
This process was supported by KIT ligand signals from the surrounding tissue and epidermis, which suppressed seno-differentiation and pushed the cells toward a tumor-prone state.
“These findings reveal that the same stem cell population can follow antagonistic fates—exhaustion or expansion—depending on the type of stress and microenvironmental signals,” Nishimura said.
“It reframes hair graying and melanoma not as unrelated events, but as divergent outcomes of stem cell stress responses,” she added.
Read More: Ferritin Face: Can Pale Skin Signal Iron Deficiency?
Not necessarily. The study does not show that people with gray hair have a lower risk of cancer.
Instead, the findings suggest that hair graying can be the result of a protective cellular response in which damaged stem cells are eliminated. When that response is bypassed, damaged McSCs may persist and contribute to melanoma development.
The researchers say the findings offer a framework for understanding how the same stem-cell population can contribute to either tissue aging or cancer depending on the type of damage and signals from the surrounding environment.
Genetics plays a major role in when hair turns gray. There are also some lifestyle changes that can prevent graying, support hair and overall health. These include:
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