Have you ever been in a situation where you felt like you needed to pee but could not use a restroom? A lot of times, especially in public, during an office meeting or an interview, we come across such circumstances, while sometimes we hold pee to not embarrass ourselves socially, or just because of the lack of facilities. Doing that often may not be good for our health.

How much pee can a person hold?

The urinary bladder is a hollow, pear-shaped organ that forms part of the urinary system. The bladder's role while is to store urine, it also releases once the limit is crossed, which is around one pint or two cups of liquid. However, under certain circumstances, it can stretch to hold more than this.

We start to fee the urge to urinate when it is filled halfway.

What can happen if you hold your pee long too often?

When you hold your pee too often, your bladder stretches and the muscle weakens. As time pass by, it can become difficult for your bladder to empty it completely. This can lead to urinary retention, and being unable to fully emptying your bladder.

Discomfort Due To Holding Pee

Pain

Ignoring the urge to pee regularly can lead to pain or discomfort in the bladder or kidneys. When you eventually make it to the bathroom, urinating might feel painful.

Additionally, the muscles involved in holding urine may remain partially tense even after you’ve emptied your bladder, potentially causing pelvic cramps.

Urinary Tract Infection

One of the most common discomforts caused by holding in pee for too long is Urinary tract infection. It can cause bacteria to multiply.

As per the Urology Care Foundation, people should avoid holding in pee for extended periods, as it increases the risk of UTIs. Dehydration, poor personal hygiene, and certain medications can also increase the risk of developing a UTI.

Common symptoms of a UTI include:

• A burning or stinging sensation during urination
• Pain in the pelvis or lower abdomen
• A persistent urge to urinate
• Strong or foul-smelling urine
• Cloudy or discolored urine
• Consistently dark urine
• Blood in the urine

Bladder Stretching

As mentioned before, in long run, regularly holding in pee could cause the bladder to stretch and make it difficult or sometimes, impossible for the bladder to contract and release pee.

If someone has a stretched bladder, sometimes, extra measures like a catheter could also be necessary.

Damage to Pelvic Floor Muscles

Regularly holding in urine can strain and potentially damage the pelvic floor muscles.

One key muscle, the urethral sphincter, helps keep the urethra closed to prevent leaks. Damage to this muscle may lead to urinary incontinence. Performing pelvic floor exercises, like Kegels, can help strengthen these muscles, repair damage, and reduce the risk of leakage.

Kidney Stones

For individuals prone to kidney stones or those with high mineral levels in their urine, holding in pee may contribute to stone formation. Urine naturally contains minerals like uric acid and calcium oxalate, which can crystallize and form stones over time.

While GLP-1 drugs like Ozempic are popular for weight loss, a new study published today in The Lancet Psychiatry journal showed that it can also help tackle the burden of depression, anxiety, and self-harm in high-risk diabetic patients.

The GLP-1 drugs, with ingredients such as semaglutide and liraglutide, were found to effectively reduce the risk of these mental health conditions in patients already taking the medications to manage their diabetes or obesity.

Also Read: ACC/AHA Cholesterol Guidelines 2026 Explained: Start Screening For Cardiovascular Diseases Early

The study found that these medications were linked to

• fewer psychiatric hospitalizations,
• taking sick leave due to mental illness,
• death by suicide.

The study comes as people with diabetes are known to have a higher risk of depression (2-3 times), anxiety (20 percent), and suicide than the general population.

“Our findings suggest that GLP-1 drugs, particularly semaglutide, might contribute to better mental health in people with diabetes and obesity,” said Jari Tiihonen, specialist physician and professor at the Centre for Psychiatry Research, Karolinska Institutet, Sweden.

Calling the results "observational", Tiihonen urged the need for controlled clinical trials to confirm the findings.

Also read: Ozempic Can Help People With Diabetes Walk Better Despite Poor Blood Flow To Legs

Key Findings

The researchers followed more than 95,000 participants diagnosed with depression or anxiety and were prescribed various antidiabetic medications through Swedish national registers between 2009 and 2022. Of the patients, 22,480 had used GLP-1 drugs.

Semaglutide, the main ingredient in Ozempic, showed the highest benefits against the mental health conditions. Semaglutide led to a:

• 42 percent reduced risk of worsening mental health
• 44 percent lower risk of worsening depression,
• 38 percent lower risk of worsening anxiety,
• 47 percent lower risk of worsening substance use disorder.

On the other hand, liraglutide, sold under the brand names Victoza (for type 2 diabetes) and Saxenda (for chronic weight management), was linked to an 18 percent lower risk of worsening mental health.

Other GLP-1 medications, including exenatide and dulaglutide, did not show the same benefit.

Also read: Oprah Winfrey Sparks Ozempic Buzz at Paris Fashion Week with Slim Figure

How Do GLP-1 Medicines Fight Against Addiction?

A recent study, published by researchers at the Washington University School of Medicine in St Louis, reported that Ozempic could prevent substance use disorder and could also treat it.

Not just the lack of will to eat food, but some people have actually reported a lack of interest in alcohol or nicotine consumption.

Previously, observational studies have also shown how it could lower the risk of alcohol and cannabis use disorders, opioid overdose, and alcohol related hospitalization.

The findings published in The BMJ showed that people taking GLP-1 drugs had a 14 percent lower risk of developing any substance use disorder.

Their substance-specific reductions:

• Alcohol use disorder risk fell by 18 percent
• Cannabis use disorder fell by 14 percent
• Cocaine and nicotine use disorders fell by 20 percent
• Opioid use disorder fell by 25 percent

Digestive problems like bloating, gas, acidity, and constipation have quietly become a common problem in our daily lives. It is common these days to find people experiencing discomfort after meals or feeling unusually heavy. While these problems may not be serious in nature, doctors say these problems have increased in recent times due to changes in the way people live and eat.

• The first major cause of these problems in recent times is the change in the way people eat. It is a known fact that people are now eating more of junk food and less of fiber-rich food. Fiber plays a crucial role in keeping digestion smooth and bowel movements normal. If the amount of fiber in the diet is low, digestion becomes slow, leading to bloating, gas, and constipation.

• Another major cause of these problems in recent times is the sedentary lifestyle people are leading these days. It is a known fact that a person should move around a lot in a day. Lack of physical activity may cause problems in digestion. Simple habits like eating quickly, missing meals, or drinking excessive carbonated beverages are some of the common causes of excessive gas and discomfort.

• Another cause of digestive upsets that is often overlooked is stress. The fact that the brain and digestive system are closely related means that digestive upsets can be caused by emotional stress. When a person is under a lot of stress, hormones are secreted into their system that can slow down digestion. As a result, a person may feel stomach upsets like tightness, bloating, irregular bowel movements, or even develop a medical condition like irritable bowel syndrome depending on their digestive system composition.

• In addition to that, other lifestyle habits like late-night meals, lack of proper sleep, dehydration, or excessive caffeine intake can cause digestive upsets. When a person’s body is out of sync, digestion is not as effective as it should be. As a result, food ferments in the stomach, leading to excessive gas production.

Traditional Remedies

Most people tend to use various remedies when they are feeling unwell.

Also Read: Why Regulatory Clarity Is Important for Safe Aesthetic Procedures in India

Remedies such as the consumption of warm water, fennel seeds, ginger tea, and the intake of probiotics in the form of curd may offer temporary relief. However, it is important to note that these might offer temporary relief and might not be effective if the symptoms of digestive discomfort are recurring.

Digestive discomforts that recur frequently should not be taken lightly. Frequent occurrences of digestive discomforts such as bloating and constipation might sometimes be symptoms of an underlying condition.

Therefore, if the symptoms of digestive discomfort last for weeks and if the symptoms also include the presence of any of the aforementioned symptoms of digestive discomfort, it might be important to consult a doctor.

Gut Problems: Need For Lifestyle Modifications

The relationship between gut health and wellbeing is also well noted. Among the lifestyle modifications that may be implemented for improved digestive health is a healthy and balanced diet, exercising regularly, adequate intake of water, stress levels, and eating at regular times.

It is a normal occurrence for people to experience bloating and gas at some point in their lives. However, if discomfort in the digestive system is a frequent occurrence, it may be a wake-up call from the body that something is amiss and deserves attention. Heeding such a call and making lifestyle modifications may work wonders for the gut.

Aesthetic medicine in India has been expanding rapidly in the past decade. There is increasing demand for more minimally invasive cosmetic treatments such as injectables (botox and dermal fillers), laser treatments, and hair restoration procedures.

According to the International Society of Aesthetic Plastic Surgery (ISAPS) report, more than 1.29 million procedures have been recorded in 2024 for cosmetic treatments. India has successfully entered the top 5 countries in the world for aesthetic procedures.

Also Read: Why Are Gut Problems Like Bloating, Gas, and Constipation Increasing Today?

Although this shows the increased demand for aesthetic medicine, there is an even larger concern that there is little to no regulation to protect the consumers.

Aesthetic Services: No Regulatory Clarity

Aesthetic services and practices in India have an unclear position which has been increasing concern for stakeholders in the industry. Medical specialties like dermatology and aesthetic medicine have been recognized fields that require training, clinical judgement, and sterile environments, but cosmetology is largely non-medical. However, that is not the case. For instance, there are many beauty centers and spas that offer procedures of medical aesthetic services like chemical peels, laser treatments, and injectables.

Regulatory clarity addresses the issue by describing who can do aesthetic procedures, and the conditions required for them to do so. Absence of such descriptions could allow low-practice and trained personnel to do procedures that carry risk for infection, scarring, burning, or other dissatisfactory results and complications. There are licensing and enforcement ambiguities that are giving the ability to practitioners to call themselves "cosmetic surgeons" without any training in plastic surgery.

Need For Strong Regulatory System

A strong system of regulations is also in the interest of uniformity in clinical practices. Regulations may lay down the minimum requirements for the infrastructure of aesthetic clinics so that they can provide sterile equipment, emergency protocols, and trained medical personnel. Regulations can also mandate obtaining informed consent, so that patients know the risks, benefits, and likely results of a procedure.

A further important role for regulations is to prevent misleading advertisements, and unscrupulous behavior. The competitive field of aesthetics invites patients based on exaggerated, and unfulfilled promises. Patients can be misled if there are no regulations to relatively eliminate the occurrence.

Trust from patients stems from regulatory transparency. Accreditation of clinics and the specialties of staff performing the procedures reassure patients regarding safety, hygiene, and postoperative care. This ultimately increases the standard of the aesthetic industry for patients and ethical practitioners.

As aesthetic medicine continues to develop in India, the evolving regulatory mechanisms will be essential in continuing to promote innovation while ensuring the safety of patients. Greater regulatory documentation, transparency from governing bodies, and public education regarding evolving safety regulations will safeguard the aesthetic space from practitioners prioritizing profit over ethics.

Besides recommending patients needing aesthetic treatment to consult a licensed plastic surgeon or dermatologist, they ensure that intricate aesthetic procedures are performed in clinical environments by qualified personnel.