Have you ever been in a situation where you felt like you needed to pee but could not use a restroom? A lot of times, especially in public, during an office meeting or an interview, we come across such circumstances, while sometimes we hold pee to not embarrass ourselves socially, or just because of the lack of facilities. Doing that often may not be good for our health.

How much pee can a person hold?

The urinary bladder is a hollow, pear-shaped organ that forms part of the urinary system. The bladder's role while is to store urine, it also releases once the limit is crossed, which is around one pint or two cups of liquid. However, under certain circumstances, it can stretch to hold more than this.

We start to fee the urge to urinate when it is filled halfway.

What can happen if you hold your pee long too often?

When you hold your pee too often, your bladder stretches and the muscle weakens. As time pass by, it can become difficult for your bladder to empty it completely. This can lead to urinary retention, and being unable to fully emptying your bladder.

Discomfort Due To Holding Pee

Pain

Ignoring the urge to pee regularly can lead to pain or discomfort in the bladder or kidneys. When you eventually make it to the bathroom, urinating might feel painful.

Additionally, the muscles involved in holding urine may remain partially tense even after you’ve emptied your bladder, potentially causing pelvic cramps.

Urinary Tract Infection

One of the most common discomforts caused by holding in pee for too long is Urinary tract infection. It can cause bacteria to multiply.

As per the Urology Care Foundation, people should avoid holding in pee for extended periods, as it increases the risk of UTIs. Dehydration, poor personal hygiene, and certain medications can also increase the risk of developing a UTI.

Common symptoms of a UTI include:

• A burning or stinging sensation during urination
• Pain in the pelvis or lower abdomen
• A persistent urge to urinate
• Strong or foul-smelling urine
• Cloudy or discolored urine
• Consistently dark urine
• Blood in the urine

Bladder Stretching

As mentioned before, in long run, regularly holding in pee could cause the bladder to stretch and make it difficult or sometimes, impossible for the bladder to contract and release pee.

If someone has a stretched bladder, sometimes, extra measures like a catheter could also be necessary.

Damage to Pelvic Floor Muscles

Regularly holding in urine can strain and potentially damage the pelvic floor muscles.

One key muscle, the urethral sphincter, helps keep the urethra closed to prevent leaks. Damage to this muscle may lead to urinary incontinence. Performing pelvic floor exercises, like Kegels, can help strengthen these muscles, repair damage, and reduce the risk of leakage.

Kidney Stones

For individuals prone to kidney stones or those with high mineral levels in their urine, holding in pee may contribute to stone formation. Urine naturally contains minerals like uric acid and calcium oxalate, which can crystallize and form stones over time.

Rubbing your eyes is a common habit, often triggered by itching, dryness or tiredness. However, frequent and vigorous rubbing can damage the cornea and increase the risk of keratoconus, a progressive condition that causes it to thin and bulge outward, experts warn.

World Keratoconus Day is observed every year on November 10 to raise awareness about the condition.

Early diagnosis is important to slow its progression. Frequent changes in spectacle prescriptions or deteriorating vision should prompt an eye examination.

Why Should You Avoid Rubbing Your Eyes?

Frequent or aggressive eye rubbing can put mechanical stress on the cornea, potentially weakening its structure and worsening existing eye conditions.

Speaking to HealthandMe, Dr Janhvi Mehta, Consultant Ophthalmologist, Jaslok Hospital and Research Centre, Mumbai, said, "Frequent or vigorous eye rubbing can damage the cornea, particularly by contributing to keratoconus. It can also cause corneal epithelial injury and worsen existing ocular allergy."

Repeated rubbing can:

• Contribute to corneal thinning and biomechanical weakening.
• Accelerate keratoconus in susceptible individuals.
• Cause corneal abrasions and increase the risk of infection.

Also read: Ozempic, Zepbound: US FDA Orders New Warning Over Rare Eye Risk

Dr Mahipal Singh Sachdev, Chairman and Managing Director, Centre for Sight Group of Hospitals, explained that excessive rubbing puts pressure on the cornea and can damage its collagen structure.

"The cornea might become thinner than usual or its shape may become uneven, leading to impaired vision. Hence, people should avoid the habit of rubbing their eyes," he told HealthandMe.

Why Are Children More At Risk?

Children with allergies, especially allergic conjunctivitis, may be more vulnerable to keratoconus because of frequent eye rubbing.

Allergies can cause persistent itching, redness, watering, and discomfort, encouraging children to rub their eyes repeatedly. The resulting mechanical stress may contribute to the development or progression of keratoconus in susceptible individuals.

The experts urged parents to watch for excessive rubbing and changes in their children's vision. Timely allergy treatment and regular eye examinations can help identify potential problems early.

Other risk factors for keratoconus include:

• Vernal keratoconjunctivitis (VKC)
• Atopic eye disease
• Family history of keratoconus
• Genetic predisposition
• Certain connective tissue disorders

However, not everyone who frequently rubs their eyes develops keratoconus.

Read More: 6 Million People In Delhi Living With Poor Vision: AIIMS Study

Why Is Keratoconus Often Diagnosed Late?

Dr Janhvi noted that keratoconus commonly begins during adolescence or early adulthood but may remain undiagnosed until vision deteriorates.

Its early symptoms can resemble common refractive errors such as myopia. Children and young adults may experience mild blurring or require frequent changes in their spectacle prescriptions, which can be mistaken for routine vision changes.

The condition can also progress gradually and initially affect only one eye, making changes harder to recognise. Routine eye examinations may not always detect early keratoconus without specialised corneal assessment, Dr. Mahipal said.

Warning signs to watch for include:

• Increasing myopia
• Progressive or irregular astigmatism
• Frequent changes in spectacle prescriptions
• Reduced visual clarity despite corrective lenses
• Ghosting, glare or double vision in one eye
• Difficulty driving at night

Increasing astigmatism despite repeated spectacle corrections is an important warning sign that warrants further evaluation.

Read More: Sudden Floaters, Flashes Or Blurred Vision? When Should You Seek Emergency Care For Retinal Changes

How Can You Prevent Corneal Damage?

Preventing excessive eye rubbing and managing its underlying causes can help reduce avoidable stress on the cornea.

1. Break the eye-rubbing habit

• Avoid pressing or massaging closed eyelids.
• Use a cold compress when your eyes itch.
• Avoid rubbing your eyes even through a towel or handkerchief.
• Keep children's fingernails short to minimise accidental injury.

2. Treat underlying allergies

If itching triggers eye rubbing, consult an ophthalmologist about appropriate treatment. Options may include topical antihistamine or mast-cell stabiliser drops, such as olopatadine or ketotifen.

Other measures include:

• Using preservative-free artificial tears for irritation
• Treating associated blepharitis or dry eye
• Avoiding prolonged use of topical steroid drops without medical supervision

3. Reduce exposure to environmental triggers

• Avoid dust, smoke and known allergens
• Wear protective glasses outdoors
• Avoid direct airflow from air conditioners.

Come Saturday morning, many people have just one thing on their mind: catching up on sleep. After a week of early mornings, office deadlines, late-night screen time and household responsibilities, the weekend feels like the perfect opportunity to stay in bed for a few extra hours. Some people even sleep until noon, believing that the extra rest will make up for all those late nights. But is it really possible to undo five days of poor sleep in just two days?

Unfortunately, the brain doesn't work that way. Sleeping longer over the weekend can certainly help you feel less tired, but it cannot completely compensate for a week of inadequate sleep.

Sleep is much more than physical rest. It is when the brain gets down to some of its most important work. Memories are processed, information gathered during the day is organised, and the brain gets an opportunity to recover from constant activity. When we repeatedly cut short our sleep, these processes can suffer.

Why Do We Feel Better After Sleeping In?

Think about how you feel after several nights of going to bed late. You may find yourself forgetting small things, struggling to concentrate during meetings or becoming unusually irritable over minor issues. These are some of the ways sleep deprivation can affect everyday functioning.

Sleeping for a few extra hours over the weekend can ease some of this fatigue. You may feel more alert and find it easier to concentrate. However, feeling refreshed is not necessarily the same as being fully recovered. Certain effects of repeated sleep restriction, particularly on attention and reaction time, can take longer to resolve.

Can Weekend Lie-ins Disturb Your Sleep Cycle?

There is another side to this weekend habit that people rarely consider. If you sleep at 11 pm during the week but stay awake until 2 or 3 am on Friday and Saturday, your body's internal clock can get disrupted.

This internal timing system, called the circadian rhythm, helps regulate when you feel sleepy and when you wake up. Large changes in sleep timings can make it harder to fall asleep on Sunday night. Before you know it, Monday morning arrives and you are back to feeling exhausted.

It becomes a familiar cycle: insufficient sleep during the week, prolonged sleep on weekends and difficulty getting back into a routine.

What Does Repeated Sleep Deprivation Do To The Brain?

One of the biggest areas affected is memory. Sleep plays an important role in consolidating information, which is why a poor night's sleep can make it harder to remember things or absorb new information the following day.

It can also affect emotional regulation. People who regularly sleep less may become more impatient, anxious or sensitive to everyday stress. Their ability to focus and make decisions may also take a hit.

Persistent sleep deprivation has also been associated with metabolic and cardiovascular problems. It is therefore important not to treat poor sleep as an unavoidable part of a demanding work schedule.

What Is A Healthier Way To Catch Up On Sleep?

Rather than depending on Saturday and Sunday to recover, try making small changes to your routine throughout the week.

• Keep a consistent schedule: Try to go to bed and wake up at roughly the same time every day.
• Don't compromise on sleep duration: Most adults need around seven to nine hours of sleep each night.
• Put your phone away before bedtime: Late-night scrolling can keep the mind stimulated and delay sleep.
• Be mindful of caffeine: That evening cup of coffee may be affecting your ability to fall asleep.
• Step outdoors in the morning: Natural daylight helps regulate the body's sleep-wake cycle.
• Pay attention to persistent tiredness: If you wake up exhausted despite getting enough sleep, speak to a doctor. Sleep disorders such as obstructive sleep apnoea may need to be ruled out.

Your brain needs rest every day, not just when the calendar says it is the weekend. Instead of treating sleep as something you can postpone and recover later, make it a non-negotiable part of your daily routine.

For decades, vaccines have transformed numerous fight against aggressive infectious diseases, saving millions of lives. Still, despite years and years of research proving their effectiveness, there is still significant skepticism surrounding vaccination. One of the most enduring claims is that vaccines, especially the measles, mumps and rubella (MMR) vaccine, can cause autism.

The belief that vaccines can cause autism has been debated for decades, despite a solid body of research failing to establish a link between the two.

In an exclusive interview with HealthandMe on World Immunization Day, Dr. Paul Offit, paediatrician and director of the Vaccine Education Center at Children’s Hospital of Philadelphia and former member of the CDC’s Advisory Committee on Immunization Practices, explained why the vaccine-autism claim is a myth difficult to debunk.

Why Is The Vaccine-Autism Issue Still Debated?

Also read: EXCLUSIVE: Ex-CDC Vaccine Advisor Says Measles Outbreak Bigger Than Reported, Slams RFK Jr’s ‘No-See Evil’ Approach

According to Dr Paul Offit, the controversy can be traced back to a 1998 paper that claimed the measles, mumps and rubella (MMR) vaccine caused autism. “I think it was born in that 1998 paper that MMR caused autism,” he said.

He said that the paper did an excellent job at convincing the masses that the adverse events related to vaccines can be long-standing and irreversible, like autism. Offit said the original claim had a lasting effect on public understanding of vaccine safety.

He said, “It’s very hard to unring the bell once you've rung it. I think it's hard to unscare people.”

He said the public-health and academic communities responded by conducting study after study to examine the alleged association. “But vaccines don't cause autism,” Offit said.

He believes that the research conducted after the 1998 paper helped address the concern. He said, “The question has been answered. Most parents of children with autism no longer believe that's the case. So I think that those studies were of value,” he said.

The 1998 paper by Andrew Wakefield and colleagues, which suggested a connection between the MMR vaccine and autism, was later retracted by The Lancet. Subsequent research has not established that MMR vaccination causes autism.

Offit said vaccines had been studied extensively as a possible environmental factor in autism. “Vaccines are probably the best studied environmental factor and that ain't it,” he said.

Autism-Vaccine Debate Is Distracting Essential Research

Also read: 'It’s The Best-Studied Vaccine In Human History': Former CDC Adviser Busts Common Myths About COVID Vaccines

Dr. Offit said that genetics plays an important role in autism, while several factors related to maternal health and pregnancy have also been associated with the condition. He said, “About 80% of autism is genetic.”

He added, “There are a number of sort of factors regarding maternal health, regarding maternal drugs, infections during pregnancy that are associated with autism.”

His comments highlight the need to understand autism through research into its different possible causes rather than focusing on vaccines. To which, Offit said that the vaccine-autism controversy has affected essential autism research.

When asked whether vaccine debates were diverting resources from research into autism causes and diagnosis, he pointed to the work of Alison Singer at the Autism Science Foundation and said there were several promising areas of investigation.

However, he criticised anti-vaccine groups for continuing to use autism as part of their arguments against vaccination. “I think that anti-vaccine groups have sadly taken the autism story hostage,” he said.

He argued that this had reduced the attention and resources that could go towards more promising areas of autism research. “So they hurt children with autism in the end,” he said.

On Revising Autism-Vaccine Debate

When asked what new evidence could make him reconsider his position on vaccines and autism, Offit said he would be open to changing his mind if a particular standard of scientific evidence were met.

“If there was an excellent retrospective study that controlled for things like healthcare seeking behavior, socioeconomic background, medical background, maternal health, et cetera, that was published in an excellent scientific journal and reproduced, then I'm willing to change my mind,” he said.

He added that a study would have to account for factors that could influence the results and be independently reproduced. “But until then, you're just hearing a lot of conspiracy theory and hand-waving,” he said.