Have you ever been in a situation where you felt like you needed to pee but could not use a restroom? A lot of times, especially in public, during an office meeting or an interview, we come across such circumstances, while sometimes we hold pee to not embarrass ourselves socially, or just because of the lack of facilities. Doing that often may not be good for our health.

How much pee can a person hold?

The urinary bladder is a hollow, pear-shaped organ that forms part of the urinary system. The bladder's role while is to store urine, it also releases once the limit is crossed, which is around one pint or two cups of liquid. However, under certain circumstances, it can stretch to hold more than this.

We start to fee the urge to urinate when it is filled halfway.

What can happen if you hold your pee long too often?

When you hold your pee too often, your bladder stretches and the muscle weakens. As time pass by, it can become difficult for your bladder to empty it completely. This can lead to urinary retention, and being unable to fully emptying your bladder.

Discomfort Due To Holding Pee

Pain

Ignoring the urge to pee regularly can lead to pain or discomfort in the bladder or kidneys. When you eventually make it to the bathroom, urinating might feel painful.

Additionally, the muscles involved in holding urine may remain partially tense even after you’ve emptied your bladder, potentially causing pelvic cramps.

Urinary Tract Infection

One of the most common discomforts caused by holding in pee for too long is Urinary tract infection. It can cause bacteria to multiply.

As per the Urology Care Foundation, people should avoid holding in pee for extended periods, as it increases the risk of UTIs. Dehydration, poor personal hygiene, and certain medications can also increase the risk of developing a UTI.

Common symptoms of a UTI include:

• A burning or stinging sensation during urination
• Pain in the pelvis or lower abdomen
• A persistent urge to urinate
• Strong or foul-smelling urine
• Cloudy or discolored urine
• Consistently dark urine
• Blood in the urine

Bladder Stretching

As mentioned before, in long run, regularly holding in pee could cause the bladder to stretch and make it difficult or sometimes, impossible for the bladder to contract and release pee.

If someone has a stretched bladder, sometimes, extra measures like a catheter could also be necessary.

Damage to Pelvic Floor Muscles

Regularly holding in urine can strain and potentially damage the pelvic floor muscles.

One key muscle, the urethral sphincter, helps keep the urethra closed to prevent leaks. Damage to this muscle may lead to urinary incontinence. Performing pelvic floor exercises, like Kegels, can help strengthen these muscles, repair damage, and reduce the risk of leakage.

Kidney Stones

For individuals prone to kidney stones or those with high mineral levels in their urine, holding in pee may contribute to stone formation. Urine naturally contains minerals like uric acid and calcium oxalate, which can crystallize and form stones over time.

Systematic Lupus Erythematosus (SLE), also known as Lupus, is a multisystem autoimmune disease in which one's immune system attacks the body. It is most common in women of reproductive age; however, in rare cases, it can present in men and patients of any age.

Lupus Symptoms: More Than Just Joint Pain

Symptoms for SLE can range from unexplained fever for days to months, to oral ulcers, malar rash, photosensitivity (after exposure to sun), hair loss, headache, stroke, seizure, abnormal behavior (psychiatry lupus). A large group of patients experiences joint swelling, pain, and fatigue. If the kidneys are affected in Lupus patients, they can pass blood with their urine.

Their urine output also decreases; their legs swell, and there is swelling around the eyes. Involvement of the heart, brain, and pancreas is also not uncommon. Lupus is one of the causes of multiple unexplained pregnancy losses, especially in the second trimester, but with proper treatment and observation, many patients do well and have an uneventful pregnancy and childbirth.

Common Myths About Lupus

Some very prominent myths about SLE need to be debunked. Many think SLE is contagious and that only women can get it, when in reality, neither is true. Being an autoimmune disease means it cannot spread by contact, and it impacts both men and women, although the incidence rate of SLE is higher for women. Many also believe in the common misconception that it affects only joints, when in reality it is a multisystem disease that can affect the kidneys, heart, brain, skin, and lungs.

There is a common myth that pregnancy is impossible or unsafe for women with Lupus; however, many women with Lupus can conceive and experience safe and healthy full-term pregnancies under the right medical guidance. Kidney biopsy, which is a required test for treating Lupus, is often deemed unsafe, but it is a safe test and is required to decide the stage of the disease and treatment.

Lupus: Warning Signs

Some symptoms that can be a cause of alarm in SLE are rapid rising serum creatinine, new onset seizure or psychosis, sudden onset shortness of breath associated with chest pain, blood in cough with low oxygen saturation, acute confusional state with fever, vision changes, severe abdominal pain, unexplained severe anemia, severe thrombocytopenia (platelet count < 20,000).

Managing Lupus

For accurate diagnosis and treatment, one needs a rheumatologist's consultation. Rheumatologists will decide the plan of treatment to manage symptoms, reduce inflammation, prevent flares of the disease, and minimize organ damage. Lifestyle measures like avoiding Sun exposure, quitting smoking, lowering stress, and engaging in some low-impact physical activities help patients to minimize the disease burden.

There is very little awareness about Lupus in society, and due to varied presentations and symptoms, patients often consult with multiple doctors of different specialties before consulting with rheumatologists. We need to push for more awareness in society about less talked-about ailments like Lupus, which needs efficient intervention and management, as it is a lifelong condition. Talking about it also helps reduce stigma and bust myths around it. Late diagnosis and delay in treatment can cause significant morbidity, disease progression, and mortality. With early diagnosis and optimal treatment.

Holistic care is possible, which goes a long way in helping individuals manage autoimmune conditions like Lupus

(By Dr Niharika Gill, Rheumatologist, Lilavati Hospital and Research Center, Mumbai)

Not long ago, heatstroke was something most people associated with spending hours outdoors in scorching heat. That picture has changed.

Heatwaves today are longer, more intense, and more frequent than they used to be. Heat-related illnesses are showing up across all age groups, and what makes heatstroke particularly dangerous is how quietly it can creep up. The body usually sends warning signals well before things get serious, but those signals get mistaken for tiredness, dehydration, or just an off day.

Catching them early can stop a medical emergency before it happens.

It Is More than Just Feeling Hot

Heatstroke happens when the body loses its ability to regulate temperature, and the core temperature starts climbing rapidly. Unlike heat exhaustion, which is uncomfortable but manageable, heatstroke is a genuine medical emergency. Left unaddressed, it can affect the brain, heart, kidneys, and other vital organs.

Most people wait for dramatic symptoms before taking it seriously. The early signs, however, are often anything but dramatic.

Warning Signs People Keep Dismissing

One of the earliest signals is feeling unusually wiped out. If someone who is normally active suddenly feels drained after doing very little, the body may be struggling to handle the heat. This often comes with dizziness, weakness, or a light-headed feeling that is hard to shake.

Persistent headaches are another sign that tends to get ignored. People blame them on poor sleep, stress, or not drinking enough water, and carry on with their day. But a headache that keeps coming back during extreme heat can mean the body is under real strain.

Other signs worth watching out for:

- Excessive thirst or a noticeably dry mouth

- Muscle cramps, especially in the legs

- Nausea or a sudden loss of appetite

- Reduced sweating even when feeling very hot

- Difficulty concentrating or feeling unexpectedly confused

On their own, each of these can seem minor. Together, they can be a sign that the body's cooling system is starting to give way.

When Things Turn Serious

As heatstroke progresses, the symptoms become harder to miss. A very high body temperature, a racing heartbeat, flushed skin, confusion, slurred speech, or out-of-character behavior are all red flags.

One of the more dangerous aspects of heatstroke is that the mental changes can be subtle enough to be mistaken for exhaustion. A person may seem disoriented, unusually irritable, or unable to think straight. Family members sometimes put it down to tiredness when it may actually mean the brain is being affected by a rapidly rising body temperature. That distinction matters.

Who Needs to Be Most Careful

Anyone can develop heatstroke, but some people carry a higher risk. Older adults, young children, outdoor workers, athletes, and people living with chronic conditions like heart disease, diabetes, or kidney disorders are particularly vulnerable. Certain medications, including diuretics and some psychiatric drugs, can also reduce the body's ability to manage temperature and stay hydrated.

Simple Steps That Make a Real Difference

Drink water throughout the day, not just when you feel thirsty. Avoid being outdoors during the hottest part of the afternoon. Wear loose, breathable clothing and get to a cool or shaded space when you can.

More than anything, pay attention to what your body is telling you. Heatstroke rarely arrives without warning. Unusual fatigue, dizziness, a persistent headache, or sudden confusion during hot weather are not things to push through and ignore.

The Bottom Line

Heatstroke is no longer an occasional summer story. As temperatures keep climbing, it is becoming a public health concern that touches more people every year.

The early warning signs are there if you know what to look for. Recognizing them and acting quickly can be the difference between recovering at home and ending up in a hospital.

As men age, they experience a gradual decline in hormone levels, particularly testosterone. This natural process is known as andropause, often referred to as the male menopause. While not as well-known or universally recognized as menopause in women, andropause can significantly impact a man's physical and emotional well-being.

Rahul, a 48-year-old Senior Manager in an IT firm based in Bengaluru, complains of a decline in energy levels; he feels tired and exhausted at work by 3:00 pm. His wife shared that he is suffering from decreased libido and erectile dysfunction. He also overthinks, because of which he remains under chronic stress. Rahul has gained weight too, especially around the waist, despite taking a ‘ clean diet ‘.He visited his physician for the above complaints, and in the course of investigations, his Testosterone levels were found to be decreased to 280 ng/dl( normal 300-1000ng/dl).

Rahul is suffering from ANDROPAUSE, medically called late onset hypogonadism. Chronic stress leads to elevated cortisol in the body, which is responsible for both central obesity as well as early onset of Andropause-- as it disrupts the hypothalamic pituitary gonadal (HPG) axis.

What Is Andropause?

Andropause refers to the age-related decline in testosterone levels and the accompanying symptoms experienced by men. Unlike menopause, which is a sudden cessation of reproductive function in women, andropause is a gradual decline in hormone production. It usually occurs in middle-aged or older men, typically starting in their 40s or 50s, although the onset and severity can vary from person to person.

Symptoms Of Andropause

The symptoms of andropause can vary widely among individuals. Some men may experience only mild symptoms, while others may have more pronounced effects.

• Decreased energy levels and fatigue: Men going through andropause often report a decrease in energy levels, feeling tired and fatigued even with adequate rest.
• Sexual changes: Many men experience a decline in sexual desire (libido) and may have difficulties achieving or maintaining erections (erectile dysfunction). Additionally, there might be a decrease in sexual spontaneity and a longer recovery time between sexual encounters.
• Mood changes: Andropause can cause mood swings, irritability, increased anxiety, and even depression in some individuals. These emotional changes may be attributed to hormonal fluctuations and the psychological impact of dealing with aging-related concerns.
• Muscle and bone changes: Testosterone plays a crucial role in maintaining muscle mass and bone density. During andropause, men may experience a decrease in muscle mass, strength, and bone density, potentially leading to increased frailty and the risk of osteoporosis.
• Changes in body composition: Andropause can contribute to an increase in body fat, particularly around the abdomen. This change in body composition can lead to a decrease in overall physical fitness and self-esteem.

Why Andropause Happens

The primary reason is the age-related decline in testosterone production. Testosterone levels typically decrease by about 1 per cent/per year after 30. Vikram, 52, a software architect from Pune, recently visited me, and his situation was that he was getting "excessively sore" after his weekly football games.

Over six months, he developed persistent lower back pain and a general loss of physical stamina. Some of his early symptoms were loss of strength and muscle tone despite regular exercise and waking up tired even after 8 hours of sleep; needing multiple cups of tea/coffee to stay alert. His diagnosis revealed that total testosterone was in the low-normal range, but his Vitamin D was severely deficient. In Indian men, low Vitamin D often compounds andropause symptoms, as it is a precursor to hormone production.

However, other factors can contribute to the onset and progression of andropause, including:

Lifestyle factors: Unhealthy lifestyle habits, such as poor diet, lack of exercise, excessive alcohol consumption, and smoking, can accelerate the decline in testosterone levels and exacerbate the symptoms of andropause.

Chronic health conditions: Certain chronic conditions, such as obesity, diabetes, hypertension, and cardiovascular disease, can affect hormone production and contribute to the development of andropause.

Medications and treatments: Certain medications, including some antidepressants, corticosteroids, and opioids, can interfere with testosterone production. Additionally, treatments like chemotherapy or radiation therapy for cancer can also impact hormone levels.

Psychological factors: Psychological stress, depression, and anxiety can have a reciprocal relationship with andropause. Hormonal changes can contribute to emotional disturbances, while emotional well-being can also influence hormone regulation.

Diagnosis

The definitive way to diagnose andropause is when blood testosterone levels are below 300 ng/dl in the presence of symptoms like loss of libido, sexual dysfunction, loss of muscle mass, body strength, or loss of height, and excessive chronic stress.

Treatment options

In India, gynecologists strictly treat female reproductive health. For "male menopause," the male equivalent specialist is the Andrologist. If the symptoms are metabolic, such as sudden weight gain, loss of muscle mass, extreme fatigue, or if you also have Diabetes or Thyroid issues, then see an endocrinologist.

Common treatments include:

Hormone replacement therapy (HRT): In some cases, testosterone replacement therapy may be recommended to address the hormonal imbalance associated with andropause. HRT can help alleviate symptoms such as low libido, fatigue, and mood changes. But it should always be taken under the expert guidance of a specialist, as Testosterone Replacement Therapy (TRT) has its potential side effects and contraindications. TRT is not for ALL.

• Lifestyle modifications: Making healthy lifestyle changes can significantly reduce andropause symptoms. Regular exercise, a balanced diet rich in essential nutrients, stress reduction techniques, and adequate sleep can help improve energy levels, mood, and overall well-being.

• Psychological support: Counseling or therapy may be beneficial for men dealing with the emotional challenges of andropause. Addressing psychological factors, learning coping mechanisms, and developing a positive mindset can help navigate this phase of life more effectively.

• Symptoms-based medication: Depending on the individual symptoms experienced during andropause, medications such as phosphodiesterase type 5 inhibitors (e.g., Viagra) may be prescribed to address erectile dysfunction, or antidepressants may be considered for mood-related concerns, but only under a doctor’s guidance.

Andropause is a natural process that many men experience as they age. It involves a gradual decline in testosterone levels and can manifest in various physical and emotional symptoms. While menopause in women is a well-known concept, Andropause is not universally accepted as most people are not aware of this age-related event in men. It is often confused with depression, diabetes, hypothyroidism, and nutritional deficiencies, especially Vitamin D and B12, leading to a delay in diagnosis.

Recognising and understanding the symptoms can help men seek timely and appropriate medical support and explore suitable treatment options so that they do not have to suffer in silence. Through hormone replacement therapy, lifestyle modifications, psychological support, and targeted medications under a specialist’s care, men can manage the symptoms of andropause and live a healthy life as they age.

(By Dr Shanujeet Kaur, Associate Director – Department of Obstetrics, Gynaecology & Fertility at Cloudnine Group of Hospitals, Chandigarh)