Drug abuse is a serious problem, which is capable of not only causing death to the one using it, but create a havoc in the lives of those who are associated with that person too. There have been plenty cases, whether it is Matthew Perry or the recent death of Liam Payne, which is in trial currently.

It is also a problem in the US and is emerging as one of the health concerns that could destroy families and society. One of the most alarming aspects of drug abuse is also its impact on public safety as well as increased crime rates. Drugs also take a heavy toll on healthcare systems as emergency departments frequently encounter cases of drug overdoses, which puts the burden on medical professional who have the strain the limited resources available.

There are also long-term health impact due to drug abuse, which includes organ damage, infectious disease, mental health disorders and rise in healthcare cost.

Are there any specific drugs which are most abused in US?

Yes. There are commonly used drugs, which also includes prescribed painkillers like oxycodone, hydrocodone, and fentanyl, as well as illicit substances like heroin. As per recent data, opioid abuse has also reached alarming levels which has affected millions of Americans.

Here are the most abused drugs in the US:

Stimulants

They are used to increase alertness, attention, and energy. They also have a high potential for abuse due to the euphoric and performance enhancing effects. Cocaine and methamphetamine are notable stimulants frequently abused in the US. As per 2019 data, 10.3 million people reported to misuse stimulants in the previous year.

Depressants

These substances are used to slow down brain activity and induce relaxation. Benzodiazepines is one of the commonly prescribed medicine. Around 4.8 million individuals in the US have misused this drug.

Other misused drugs and its affects on the health:

Opioids:

It could lead to slow breathing and heart rate. It can also increase the risk of overdose and respiratory failure, constipation and a weakened immune system.

Stimulants:

It can elevate heart rate and blood pressure. It could also increase body temperate and lead to an irregular heartbeat. Furthermore, one can experience loss of appetite and weight loss.

Cannabis:

This can alter perception and coordination. People who consume it often have red eyes and a dry mouth. This can increase appetite, sometimes the "munchies" can reach to a point of no return and it could impair memory and cognitive function.

Benzodiazepines:

It could lead to sedation and drowsiness and an impaired coordination and balance. There also could be memory problems and confusion, along with respiratory depression, when combined with other depressant substance.

Alcohol:

This could lead to slurred speech, impaired condition, poor judgment and decision-making, liver damage and cirrhosis and an increased risk of accidents and injuries, which is the 3rd most leading cause of death in the US.

Additional Negative Impact: Social and psychological

Substance abuse impairs job performance and reliability, leading to frequent absenteeism, reduced productivity, and even job loss. This further leads to financial instability, strained relationships, and a cycle of dependency.

It was during the COVID-19 pandemic that Annabelle Gurwitch, an American author, actress, and television host, developed a "a little persistent cough".

Suspecting it to be a COVID symptom, Annabelle went for a check-up. Her doctor alarmingly informed her about something suspicious on her lungs. Soon after, an X-ray and a biopsy confirmed her diagnosis of stage 4 cancer.

But, here's the catch. Annabelle is a non-smoker. She also lived a healthy lifestyle and exercised every day, and felt like she was in really good health, besides the persistent little cough.

Also read:American Author Annabelle Gurwitch Writes New Memoir On Stage-4 Lung Cancer Diagnosis

HealthandMe spoke to health experts to understand how a persistent cough signals the risk of lung cancer.

If you, too, are a non-smoker who is leading a healthy lifestyle and has no medical conditions other than a persistent cough, then you must visit your doctor right away, advised the experts.

"A persistent cough can be an early warning sign of lung cancer, especially when it shows specific features rather than behaving like a routine respiratory illness," Dr Sameer Khatri, Principal Director - Medical Oncology, Max Super Speciality Hospital, Patparganj, told HealthandMe.

The doctor noted that the cough becomes suspicious when it persists beyond three weeks without a clear cause or fails to respond to standard symptomatic treatment such as cough syrups, bronchodilators, etc.

"A change in a pre-existing smoker’s cough—for example, becoming more frequent, severe, or different in character—is particularly important. In non-smokers, a new, unexplained chronic cough should not be ignored," Dr. Khatri said.

Certain associated symptoms further strengthen the suspicion of cancer. The most significant is hemoptysis, the coughing up of blood or blood-stained mucus, even if minimal.

Other red flags include

• unintentional weight loss,
• chest pain,
• breathlessness,
• hoarseness,
• recurrent pneumonia in the same lung region.
• age >40 years,
• smoking history, occupational exposures.

Persistent cough: TB Vs Lung Cancer

Persistent cough also signals the risk of tuberculosis (TB) -- the world's most deadliest infectious disease. Understanding the differences between these two causes is critical for early diagnosis and timely treatment.

Dr Seema Jagiasi from MOC Cancer Care Center told HealthandMe that the cough in TB may sometimes produce blood-tinged phlegm, but it is usually associated with signs of infection, such as fatigue and a general feeling of illness.

TB is more common in younger populations and in individuals with weakened immunity or poor living conditions.

"In contrast, a cough associated with lung cancer tends to be more insidious. It may start as a dry, persistent cough that gradually worsens over time. Unlike TB, it may not initially present with fever or infection-related symptoms," the doctor explained.

Also read: Suffering From Mid-back Pain? Doctors Say It May Be Spinal TB

One of the key differences lies in progression and response to treatment.

TB is treatable with a course of antibiotics, and symptoms often improve within weeks of starting therapy. However, a lung cancer-related cough persists or worsens despite routine medications.

Dr Jagiasi emphasized that any cough lasting beyond three weeks, especially when accompanied by alarming symptoms, should not be ignored.

"Early investigations, such as chest imaging and further diagnostic tests, can help distinguish between the two conditions," the doctor said.

While both TB and lung cancer may present with a persistent cough, their underlying causes, associated symptoms, and progression differ significantly.

The health experts called for more awareness and the need for timely medical evaluation for the effective management of the disease.

Irish Actor Michael Patrick, known for his significant role in Game of Thrones, has sadly passed away at the young age of 35.

Sharing the news in a post on social media platform Instagram, his wife Naomi Sheehan shared that Michael Patrick (whom she fondly calls Mick) died after a years-long battle with Motor Neurone Disease.

"Last night, Mick sadly passed away in the Northern Ireland Hospice. He was diagnosed with Motor Neurone Disease on 1st February 2023. He was admitted 10 days ago and was cared for by the incredible team there. He passed peacefully, surrounded by family and friends," Naomi said.

Calling Michael a "titan of a ginger-haired man", she said that “Words can’t describe how broken-hearted we are".

Naomi called Michael an "inspiration to everyone."

Also read: Dismissed as Anxiety: Terry Crew’s Wife Rebecca Shares Decade-Long Struggle With Parkinson’s

What Is Motor Neurone Disease (MND)

MND is a rare and progressive neurodegenerative disease. According to NHS UK, it causes muscle weakness that gets worse over a few months or years. It's usually life-shortening, and there's currently no cure, but treatment can help manage the symptoms.

Symptoms of MND include:

• stiff or weak hands
• weak legs and feet
• twitches, spasms, or muscle cramps (where muscles painfully tighten).

It makes everyday tasks such as climbing stairs or gripping objects difficult.

Also read: Grey’s Anatomy Star Eric Dane Dies After ALS Battle

As the disease advances, patients may develop difficulties with breathing, swallowing, and speech, along with changes in mood or personality. In later stages, walking and movement can become extremely limited.

Treatment of MND

About 1,500 people are diagnosed with MND each year, yet treatment choices remain scarce. Only a small proportion of patients currently qualify for therapies that target the disease process itself.

MND can be difficult to diagnose in the early stages. But as the symptoms get worse, it can usually be confirmed.

Tests used to help diagnose MND include:

• blood tests
• tests to check how well your nerves are working
• an MRI scan to help rule out other conditions that affect the brain and nerves

1. Amyotrophic lateral sclerosis (ALS): Early symptoms include muscle weakness in the arms and legs can cause you to trip and drop things.

2. Progressive bulbar palsy (PBP): It mainly affects muscles in the face, throat, and tongue, causing slurred speech and problems swallowing.

3. Progressive muscular atrophy (PMA): It causes weakness in the hands.

4. Primary lateral sclerosis (PLS): Leads to weak legs, sometimes with other symptoms, including speech problems.

Common treatment options for MND include:

• physiotherapy and exercises to help with muscle weakness and stiffness
• dietary advice to help you maintain weight
• speech and language therapist to help with talking
• Cognitive behavioral therapy (CBT) to help cope with emotions and feelings, such as anxiety and depression.

During the COVID-19 pandemic, the SARS-CoV-2 virus had a significant impact on the eyes, causing conjunctivitis (pink eye), with red, itchy, watery, or painful eyes.

A new study now shows that eye symptoms may also be key in understanding the severity of long COVID, a collection of symptoms that last three months or longer after your first COVID symptoms.

The new study, published in the journal Clinical Ophthalmology, showed that the new onset of eye symptoms in people with long COVID may be an indicator of more severe disease.

Also read: Long Covid Causes Lasting Brain Inflammation And Lung Injury, Reveals Study

Key Findings

Researchers from the Yale School of Medicine analyzed survey data from 595 adults who self-reported having long COVID in surveys conducted from May 2022 to October 2023. They found that nearly 60 percent of people reported new-onset of ocular symptoms.

The findings suggest that ocular symptoms in long COVID may be interpreted as vision-related manifestations that cluster with systemic post-COVID conditions. The symptoms include a new onset of :

• blurred or lost vision,
• dry eyes,
• floaters or flashes

Notably, individuals with ocular symptoms reported:

• A greater overall symptom burden,
• Financial difficulties,
• Challenges in everyday life.

Also read: Long COVID: The Story Of Those Who Are Still Dealing With Symptoms And Illnesses

What is Long COVID

Long COVID includes a wide range of symptoms or conditions that may improve, worsen, or be ongoing. While anyone who gets COVID-19 can develop Long COVID, studies have shown that some groups of people are more likely to develop Long COVID than others, including:

• Women
• People who have experienced more severe COVID-19 illness, especially those who were hospitalized or needed intensive care
• People with underlying health conditions
• People who did not get a COVID-19 vaccine

While many of the Long COVID conditions remain to be fully recognized, some people have more than one symptom that can be moderate to severe, and also impact the quality of life. According to the US CDC, they include:

• Tiredness or fatigue
• Difficulty thinking or concentrating (sometimes called “brain fog”)
• Shortness of breath or difficulty breathing
• Headache
• Dizziness on standing
• Fast-beating or pounding heart (known as heart palpitations)
• Chest pain
• Cough
• Joint or muscle pain
• Depression or anxiety
• Fever
• Loss of taste or smell