What Are The Most Abused Drugs In The US?

Updated Nov 29, 2024 | 05:00 AM IST

SummaryFrom prescription opioids to illicit drugs, understanding the most abused substances in the US sheds light on a crisis impacting health, families, and society at large.
Drug abuse in the US

Credits: Canva

Drug abuse is a serious problem, which is capable of not only causing death to the one using it, but create a havoc in the lives of those who are associated with that person too. There have been plenty cases, whether it is Matthew Perry or the recent death of Liam Payne, which is in trial currently.

It is also a problem in the US and is emerging as one of the health concerns that could destroy families and society. One of the most alarming aspects of drug abuse is also its impact on public safety as well as increased crime rates. Drugs also take a heavy toll on healthcare systems as emergency departments frequently encounter cases of drug overdoses, which puts the burden on medical professional who have the strain the limited resources available.

There are also long-term health impact due to drug abuse, which includes organ damage, infectious disease, mental health disorders and rise in healthcare cost.

Are there any specific drugs which are most abused in US?

Yes. There are commonly used drugs, which also includes prescribed painkillers like oxycodone, hydrocodone, and fentanyl, as well as illicit substances like heroin. As per recent data, opioid abuse has also reached alarming levels which has affected millions of Americans.

Here are the most abused drugs in the US:

Stimulants

They are used to increase alertness, attention, and energy. They also have a high potential for abuse due to the euphoric and performance enhancing effects. Cocaine and methamphetamine are notable stimulants frequently abused in the US. As per 2019 data, 10.3 million people reported to misuse stimulants in the previous year.

Depressants

These substances are used to slow down brain activity and induce relaxation. Benzodiazepines is one of the commonly prescribed medicine. Around 4.8 million individuals in the US have misused this drug.

Other misused drugs and its affects on the health:

Opioids:

It could lead to slow breathing and heart rate. It can also increase the risk of overdose and respiratory failure, constipation and a weakened immune system.

Stimulants:

It can elevate heart rate and blood pressure. It could also increase body temperate and lead to an irregular heartbeat. Furthermore, one can experience loss of appetite and weight loss.

Cannabis:

This can alter perception and coordination. People who consume it often have red eyes and a dry mouth. This can increase appetite, sometimes the "munchies" can reach to a point of no return and it could impair memory and cognitive function.

Benzodiazepines:

It could lead to sedation and drowsiness and an impaired coordination and balance. There also could be memory problems and confusion, along with respiratory depression, when combined with other depressant substance.

Alcohol:

This could lead to slurred speech, impaired condition, poor judgment and decision-making, liver damage and cirrhosis and an increased risk of accidents and injuries, which is the 3rd most leading cause of death in the US.

Additional Negative Impact: Social and psychological

Substance abuse impairs job performance and reliability, leading to frequent absenteeism, reduced productivity, and even job loss. This further leads to financial instability, strained relationships, and a cycle of dependency.

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World Liver Day 2026: Origin, Theme, and Significance

Updated Apr 19, 2026 | 07:00 AM IST

SummaryFrom filtering toxins to aiding in digestion and metabolism, the liver silently performs over 500 crucial functions in the body. The liver is the only organ blessed with the ability to regenerate itself. Yet, data show that 2 million lives worldwide are lost each year to liver disease. About 1.5 billion people suffer from chronic liver disease.
World Liver Day 2026: Origin, Theme, and Significance

Credit: Canva

World Liver Day 2026 is observed every year on April 19 to raise awareness of the importance of liver health, focusing on preventing diseases such as cirrhosis and fatty liver through healthy lifestyles.

The liver is a key organ that filters blood, breaks down food, stores energy, and keeps the human body in balance.

However, rising metabolic risk factors, including high blood sugar and obesity, are increasingly driving cases of metabolic dysfunction-associated steatotic liver disease (MASLD).

Nearly one-third of the global adult population today lives with MASLD, which can remain asymptomatic for years but turn into deadly scarring (fibrosis), cirrhosis (advanced fibrosis and loss of some of the liver function), or even liver cancer.

World Liver Day: Origin

The European Association for the Study of the Liver (EASL) launched World Liver Day in 2010. The day was established on April 19 to commemorate the EASL's founding in 1966.

World Liver Day 2026: Theme

This year, 2026, the World Liver Day theme is “Solid Habits, Strong Liver”. It emphasizes building consistent lifestyle habits, such as balanced diet, regular exercise, avoiding alcohol, and routine check-ups, to strengthen liver health and prevent diseases.

Burden Of Liver Diseases

https://www.youtube.com/watch?v=zklb3ZCyX2o

From filtering toxins to aiding in digestion and metabolism, the liver silently performs over 500 crucial functions in the body. The organ is also blessed with the ability to regenerate itself.

Yet data shows that 2 million lives worldwide are lost each year to liver disease. About 1.5 billion people suffer from chronic liver disease.

MASLD, formerly known as non-alcoholic fatty liver disease (NAFLD), has emerged as the most common liver condition worldwide. These patients suffer from either obesity, diabetes, metabolic syndrome, hypertension, or cholesterol problems.

According to a recent study published in The Lancet Gastroenterology & Hepatology journal, MASLD affected 1.3 billion people around the globe in 2023.

The alarming study estimates the numbers to further spike by over 38 percent to reach 1.8 billion cases by 2050, causing substantial health and economic impacts worldwide.

MASLD remains one of the most prevalent and rapidly growing liver conditions worldwide, with its prevalence marking a 143 percent increase between 1990 and 2023.

Also read: Why Regular Scans Are Crucial for Liver Cancer Patients: Doctors Explain

People with obesity, diabetes, central or abdominal fat, dyslipidemia, hypertension, and insulin resistance are more likely to have MASLD. Obesity is the strongest risk factor, with the likelihood rising steeply from overweight to severe obesity.

Other signs to watch for include

  • persistent fatigue
  • Digestive issues and bloating
  • Unexplained weight gain or difficulty losing weight
  • Skin changes

Everyday Habits That Harm The Liver

Certain lifestyle choices can accelerate liver damage, such as:

  • Overeating processed or fried foods
  • High sugar intake (soft drinks, sweets, desserts)
  • Physical inactivity or prolonged sitting
  • Ignoring health issues like diabetes or hypertension
  • Crash dieting or taking unprescribed supplements.

How To Improve Liver Health?

Early screening and detection are key to prevent irreversible stages. Yet liver disease can be prevented with lifestyle changes such as:

  • Eating a balanced diet with vegetables, fruits, whole grains, and lean protein
  • Engaging in at least 30 minutes of exercise daily
  • Staying hydrated to help the liver flush out toxins
  • Avoiding alcohol and smoking
  • Avoiding self-medication and unnecessary pills
  • Getting routine health screenings.

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Why Irritable Bowel Syndrome Is Rising Among Young Working Adults

Updated Apr 19, 2026 | 08:00 AM IST

SummaryWorld Irritable Bowel Syndrome Day is held annually on April 19th to raise global awareness, reduce stigma, and support the roughly 700 million people worldwide suffering from the condition.
Why Irritable Bowel Syndrome Is Rising Among Young Working Adults

Credit: Canva

A growing number of young professionals aged 18 to 30 are being diagnosed with Irritable Bowel Syndrome (IBS), a trend that is linked to the pressures and habits of modern life, said health experts today.

World Irritable Bowel Syndrome Day is held annually on April 19th to raise global awareness, reduce stigma, and support the roughly 700 million people worldwide suffering from the condition.

According to health experts, the combination of long hours in the office, irregular diets, high-stress levels, and lack of physical activity has paved the way for a lifestyle that is making young adults increasingly susceptible to developing symptoms related to their gut.

Speaking to HealthandMe, Dr. Nidhi Rawal, Consultant - Pediatric Gastroenterologist and Hepatologist, Rainbow Hospital, explained the major risk factors that are taking a visible toll on digestive health.

1. Chronic stress

Young professionals are faced with a fast-paced job environment full of obstacles and demands that they experience daily, along with performance pressure and increased digital overload; all of these factors can hurt the gut-brain axis.

When the gut-brain axis becomes disrupted, the motility and sensitivity of the digestive system can be affected, producing gut-related symptoms, such as abdominal discomfort, excessive gas, and changes in bowel movements.

2. Dietary habits

The increased reliance on processed foods, increased frequency of ordering takeout and fast food, excessive caffeine consumption, and irregular meal schedules can disrupt digestion and alter the balance of healthy vs unhealthy microbiota in the digestive tract.

3. Skipping meals

Skipping meals or eating a late dinner can also raise risk of IBS, and worsen symptoms.

4. Lack of physical activity

Being sedentary for long periods of time results in slowing the digestion process and therefore increases the risk of constipation and bloating.

5. Poor sleeping habits

Common among people in this age group, this also affect hormones and digestion negatively.

6. Better access to diagnostic tests

Better access to diagnostic tests and awareness are leading to an increase in diagnosis of the condition, that can also enable faster treatment and early recovery.

What Is IBS?

Irritable Bowel Syndrome (IBS) is a common but often overlooked gastrointestinal disorder, and less than 15 per cent get diagnosed.

Common symptoms include

  • bloated abdomen,
  • abdominal pain,
  • gas,
  • diarrhea,
  • constipation.

Why IBS Symptoms Are Often Ignored

IBS remains undiagnosed for many years as people tend to normalize these symptoms over time or attribute them to "something they ate" or everyday stresses.

One reason for this delay in being diagnosed is that the symptoms occur intermittently.

It is also important to note that the presentation of these symptoms is inconsistent and unpredictable; there may be episodes where the IBS can last many days, and then completely resolve, thus providing a false sense of relief.

Therefore, many individuals choose to delay consulting with a physician due to their belief that the symptoms they are experiencing are not serious.

Another contributing factor is that there is still a degree of reluctance or discomfort associated with discussing problems related to the gastrointestinal tract openly; this only further complicates under-reporting statistics.

IBS is a functional disorder. Therefore, routine diagnostic testing will not reveal any visible abnormalities.

Many patients may assume that the symptoms they are experiencing are not "real" or are not significant enough to warrant seeking medical attention, even though the discomfort they experience can be quite significant and affect their daily lives.

To treat IBS effectively, those suffering from it need to adopt some lifestyle changes, such as

Regular mealtimes,

A balanced diet,

Exercise,

Stress reduction.

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HPV Vaccines Can Prevent Head And Neck Cancers In Men, Says Study

Updated Apr 18, 2026 | 10:30 PM IST

SummaryThe study, published in JAMA Oncology, showed that men and boys who received the HPV vaccine from ages nine to 26 were nearly 50 per cent less likely to develop cancers of the head and neck, esophagus, anus, or penis.
HPV Vaccines Can Prevent Head And Neck Cancers In Men, Says Study

Credit: Canva

While vaccinations against human papillomavirus (HPV) are key to preventing cervical cancers in women, a new study has shown that the shots can also lead to a significant risk of head and neck cancers in men and boys.

The study, published in JAMA Oncology, showed that men and boys who received the HPV vaccine from ages nine to 26 were nearly 50 per cent less likely to develop cancers of the head and neck, esophagus, anus, or penis.

The results show the importance of vaccinating all children and teens against HPV, said Taito Kitano, DrPH, first author of the study and a researcher at Nara Prefecture General Medical Center in Nara, Japan, CIDRAP News reported.

“Children, adolescents, parents, and health care workers should be more informed about the expected benefits of the HPV vaccine, not just cervical cancer,” Kitano added.

The study included more than 510,000 boys and men vaccinated between January 2016 and December 2024, along with an equal number of unvaccinated males.

Vaccinated participants in the study were given shots that prevent infection with nine strains of HPV.

What Are HPV-related Cancers in Men

HPV-related head and neck cancers often develop in the back of the mouth and throat. They are asymptomatic in the early stages and are typically found only after they cause pain or swelling.

However, by the time these symptoms begin to appear, the cancers are often larger and more advanced, making them harder to cure.

Earlier this year, the European Cancer Organization noted in a LinkedIn post urged for HPV vaccine for all people, regardless of gender.

"HPV affects everyone, regardless of gender. It can lead to cancers of the cervix, mouth and throat, anus, and penis. This is why universal protection is so important," it said.

According to Dr David Pfister, an oncologist at Memorial Sloan Kettering Cancer Centre, New York, the HPV vaccine protects men from penile, neck, and head cancer. He also noted that while a pap test detects early-stage cervical cancer in women, no such test exists for penile, anal, or head and neck cancers in men, which can worsen their survival rate.

"Developing something like a pap test for throat cancer would be a game-changer. When you compare the throat to the cervix, the anatomy of sites like the tonsils and the base of the tongue has hard-to-reach crevices in which the virus can hide," Dr Pfister explained.

"Until an effective and reliable screening test is developed, patients should stay up to date on their HPV vaccines, know how the disease is acquired, and take any suspicious symptoms like a lump in the neck or blood in the phlegm to their doctor or dentist," he added.

The findings have important implications for vaccination policies. HPV vaccination programs have focused primarily on women because of the link between HPV and cervical cancers. The study provides evidence that HPV vaccination should be accessible irrespective of sex.

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