Drug abuse is a serious problem, which is capable of not only causing death to the one using it, but create a havoc in the lives of those who are associated with that person too. There have been plenty cases, whether it is Matthew Perry or the recent death of Liam Payne, which is in trial currently.

It is also a problem in the US and is emerging as one of the health concerns that could destroy families and society. One of the most alarming aspects of drug abuse is also its impact on public safety as well as increased crime rates. Drugs also take a heavy toll on healthcare systems as emergency departments frequently encounter cases of drug overdoses, which puts the burden on medical professional who have the strain the limited resources available.

There are also long-term health impact due to drug abuse, which includes organ damage, infectious disease, mental health disorders and rise in healthcare cost.

Are there any specific drugs which are most abused in US?

Yes. There are commonly used drugs, which also includes prescribed painkillers like oxycodone, hydrocodone, and fentanyl, as well as illicit substances like heroin. As per recent data, opioid abuse has also reached alarming levels which has affected millions of Americans.

Here are the most abused drugs in the US:

Stimulants

They are used to increase alertness, attention, and energy. They also have a high potential for abuse due to the euphoric and performance enhancing effects. Cocaine and methamphetamine are notable stimulants frequently abused in the US. As per 2019 data, 10.3 million people reported to misuse stimulants in the previous year.

Depressants

These substances are used to slow down brain activity and induce relaxation. Benzodiazepines is one of the commonly prescribed medicine. Around 4.8 million individuals in the US have misused this drug.

Other misused drugs and its affects on the health:

Opioids:

It could lead to slow breathing and heart rate. It can also increase the risk of overdose and respiratory failure, constipation and a weakened immune system.

Stimulants:

It can elevate heart rate and blood pressure. It could also increase body temperate and lead to an irregular heartbeat. Furthermore, one can experience loss of appetite and weight loss.

Cannabis:

This can alter perception and coordination. People who consume it often have red eyes and a dry mouth. This can increase appetite, sometimes the "munchies" can reach to a point of no return and it could impair memory and cognitive function.

Benzodiazepines:

It could lead to sedation and drowsiness and an impaired coordination and balance. There also could be memory problems and confusion, along with respiratory depression, when combined with other depressant substance.

Alcohol:

This could lead to slurred speech, impaired condition, poor judgment and decision-making, liver damage and cirrhosis and an increased risk of accidents and injuries, which is the 3rd most leading cause of death in the US.

Additional Negative Impact: Social and psychological

Substance abuse impairs job performance and reliability, leading to frequent absenteeism, reduced productivity, and even job loss. This further leads to financial instability, strained relationships, and a cycle of dependency.

Subtle personality shifts are often brushed off as stress, burnout, or simply aging; however, experts speaking to The Telegraph UK said that, in many families, behavior changes appeared years before memory problems ever showed up. Long before forgetting names or misplacing keys, the brain sometimes reveals distress through temperament.

Here are the personality patterns specialists consider early warning signs.

Loss Of Confidence

One of the earliest changes families notice is a sudden drop in self belief. A person who once handled responsibilities with ease may start doubting routine decisions. Tasks they previously mastered begin to feel overwhelming.

This does not look like ordinary ageing. It feels abrupt and out of character. People may avoid activities they enjoyed, stop fixing things around the house, or repeatedly seek reassurance.

The reason lies in declining brain flexibility. When brain networks struggle to process information efficiently, the individual senses something is wrong even before memory fails. Many withdraw socially, which further increases cognitive decline risk because isolation deprives the brain of stimulation.

Becoming Less Curious Or Open

Everyone becomes slightly set in their ways with age. But a marked shift toward rigid thinking can be significant.

Someone once eager to try new foods, travel, hobbies, or conversations may now resist anything unfamiliar. They prefer repetitive routines and become uncomfortable with change.

This matters because curiosity acts like exercise for the brain. Reduced openness means fewer new neural connections being formed. Over years, that lack of stimulation weakens resilience against degeneration.

Families often interpret this as stubbornness. In reality, the brain may be losing its ability to adapt.

Difficulty Handling Problems

A striking early sign is emotional collapse over manageable situations. People who previously handled pressure calmly may suddenly panic over bills, schedules, or minor setbacks.

They might abandon responsibilities, become overwhelmed quickly, or react with distress disproportionate to the problem.

This happens because the brain’s coping reserve shrinks slowly over time. The person is not overreacting intentionally. They genuinely cannot process the situation the way they once could.

Often, this stage appears many years before diagnosis.

Rising Impulsivity

Uncharacteristic impulsive behavior can be a strong warning sign. This may include reckless spending, gambling, inappropriate jokes, blunt comments, or risky decisions.

The change is especially noticeable when the person was previously cautious.

This reflects weakening control centres in the brain that regulate inhibition. The desire may always have existed, but the filter disappears. Families sometimes mistake this for a personality crisis or rebellion rather than a neurological change.

Reduced Conscientiousness

Another overlooked sign is declining organization. Bills go unpaid, appointments are missed, and routines fall apart.

The person may appear lazy, careless, or uninterested in hygiene or planning. In truth, the brain’s planning circuits are struggling.

Interestingly, people who maintain structured habits tend to have lower dementia risk. When those habits suddenly erode, it may indicate underlying biological changes rather than attitude.

Increased Anxiety And Emotional Fragility

Heightened nervousness often emerges early. Individuals become unusually worried, tense, or easily rattled. Minor uncertainties feel threatening.

Chronic stress affects inflammation levels in the body and brain, which accelerates damage to nerve cells. The emotional change can therefore be both a symptom and a driver of decline.

Families frequently interpret this as midlife stress, but persistence and personality mismatch are key clues.

Loss Of Warmth And Empathy

Perhaps the most distressing shift is emotional distancing. Someone affectionate may grow indifferent, withdrawn, or blunt. They may stop comforting loved ones or show little reaction to emotional events.

This does not mean they care less. The brain regions responsible for social understanding and emotional recognition are weakening.

Such changes are often mistaken for depression or relationship problems, delaying evaluation.

When Should You Be Concerned

A single change alone rarely means dementia. What matters is a consistent shift from lifelong behavior. If reactions feel unfamiliar compared to how the person handled situations for decades, it deserves attention.

In many cases, personality changes appear years before memory loss. Recognizing them early allows families to seek assessment, improve lifestyle factors, and prepare support systems while independence remains intact.

The brain often whispers before it forgets. Listening to behavior can be the first step toward protecting it.

Heart attack is the world's number one killer, yet its symptoms differ for both men and women, leading to varied outcomes.

A heart attack typically occurs when cholesterol plaque builds inside the walls of arteries and causes damage to the major blood vessels.

While men typically develop plaque in the largest arteries that supply blood to the heart, in women, it accumulates in the heart’s smallest blood vessels, known as the microvasculature.

A study published today in Circulation: Cardiovascular Imaging, an American Heart Association journal, showed that women report less artery-clogging plaque. Yet, it did not protect them from heart disease compared to men.

The study showed that women faced increased heart risk at lower levels of plaque compared to men. For total plaque burden, women’s risk began to rise at 20 percent plaque burden, while men’s risk started at 28 percent.

The increasing plaque levels led to a sharper risk for women than for men.

How Heart Attack Symptoms Differ Between Men And Women

According to global studies, women are more likely than men to die from a heart attack. The major reason is the late onset of symptoms of a heart attack in women.

During a heart attack, men are likely to experience sweating, pain in the chest, arms, and legs, and shortness of breath.

While the experiences are common among women, they also tend to suffer a combination of less-recognized symptoms such as nausea, indigestion, fatigue, dizziness, and pain in the neck, jaw, throat, abdomen, or back.

The obvious chest discomfort is also sometimes absent during heart attacks in women.

Other common reasons for heart attacks in women include:

• High testosterone levels before menopause
• Hypertension during menopause
• Autoimmune diseases such as rheumatoid arthritis
• Stress and depression

Can Heart Attacks Be Prevented?

Cardiovascular diseases are mostly preventable by targeting traditional risk factors common to both women and men, which include obesity, smoking, diabetes, high blood pressure, family history and metabolic syndrome -- the co-existence of high blood pressure, obesity, and high glucose and triglyceride levels.

The American Heart Association also advises at least 150 minutes a week of moderate-intensity aerobic activity (such as brisk walking) or 75 minutes of vigorous activity (such as jogging), or a combination of both.

Include fruits, vegetables, lean proteins, whole grains, low-fat or fat-free dairy, nuts, and seeds in your diet.

Limit processed foods, added sugars, sodium, and alcohol.

Seeing your child suddenly screaming at night, with wide eyes and thrashing limbs, can be deeply unsettling. However, remaining calm and focusing on safety is crucial for parents during the sleep terror episodes, said health experts.

Sleep terrors, also known as night terrors, are episodes of sudden fear, screaming, or intense distress that occur during sleep.

The condition is more common in children, especially between the ages of 3 and 8 years, as their sleep patterns are still maturing.

Unlike nightmares, which usually happen during dreaming (REM sleep) and are often remembered, sleep terrors occur during deep non-REM sleep.

Dr Preeti Singh, Senior Consultant, Clinical Psychology, Max Super Speciality Hospital, Dwarka told HealthandMe, that while it may be frightening to witness, especially for parents, sleep terrors themselves are usually not harmful.

Although most kids outgrow this naturally, if the episodes are violent or very frequent, consult a specialist, added Dr Sudhir Kumar, a neurologist at Apollo Hospitals, Hyderabad.

What Are Sleep Terrors

During sleep terror, the child may sit up abruptly, shout, appear frightened, sweat, breathe rapidly, and be difficult to console. In most cases, they do not recall the episode the next morning.

Sleep terrors typically occur in the first third of the night, during deep sleep (slow-wave sleep). They are considered a type of parasomnia, meaning an unusual behavior during sleep.

Dr Kumar, in a post on social media platform X, explained that unlike a bad dream, a sleep terror happens in deep sleep (Stage N3).

It is characterized by abrupt sitting up/screaming, with physical signs that include a fast heart rate, sweating, and dilated pupils.

"It is 11 PM. Your child suddenly sits up, screams at the top of their lungs, and looks terrified. They are not responding to you, and they seem to be looking right through you. This is likely a sleep terror (night terror), a common NREM sleep parasomnia in children aged 3-12,” said Dr Kumar, popularly known as the Hyderabad doctor, on X.

The expert noted that the children are unlikely to recognize the parents and be "consoled" during the episodes.

What Factors Trigger Sleep Terrors

• Sleep deprivation or irregular sleep schedules
• Fever or illness
• Emotional stress or anxiety
• Major life changes or trauma
• Family history of parasomnias
• Certain medications

For children, sleep terrors are often developmental and tend to reduce as the nervous system matures, Dr Singh told HealthanMe.

How Can Parents Respond?

Parents often feel alarmed during a sleep terror episode, but the key is to remain calm, the experts said. They said during an episode:

• Do not try to fully wake the child, as this may increase confusion and agitation.
• Gently ensure the child is safe and cannot injure themselves.
• Speak softly and reassuringly, even if they do not respond.
• Wait for the episode to pass, which usually happens within a few minutes.

Other preventive measures include:

• Maintaining a consistent bedtime routine
• Ensuring the child gets adequate sleep
• Reducing screen time before bed
• Managing stress during the day
• Creating a calm and secure sleep environment

How To Manage

Most children do not require medical treatment, as sleep terrors usually resolve on their own with age. Treatment is considered when episodes are frequent, severe, cause injury, or significantly disrupt family life.

However, addressing sleep deprivation, treating any underlying medical conditions (e.g., sleep apnea), counseling or stress management strategies can help.