Wegovy Users Maintain Weight Loss for 4 Years: Here's How It Works

Updated Dec 3, 2024 | 09:00 PM IST

SummaryWegovy, is primarily an antidiabetic medication used to treat Type 2 diabetes. People receiving weight-loss drug Wegrovy sustained weight loss for up to four years
wegovy

wegovy (Credit: Canva)

People receiving weight-loss drug Wegovy sustained weight loss for up to four years, shedding an average of 10% of their body weight in that time, as per a new study. Wegrovy is a brand that markets semaglutide injections, that have gained widespread attention for their weight-loss effects. The study also found that Semaglutide injections boost an individual's heart health, even when weight loss doesn't take place.

The study, called SELECT, was published in journal Nature Medicine. "At four years, we see ongoing benefits of semaglutide," said Cheng-Han Chen, MD, interventional cardiologist from Cardiologist, who was not involved in the research. Besides the weight loss, it also lead to a loss in cardiovascular outcomes.

The research was conducted on 17000 adults, who had obesity but did not have diabetes. Overall, people who received once-weekly injections of semaglutide lost on average 10.2% of their body weight over the course of four years. All of the study participants continued to lose weight for about 65 weeks, a year and three months, and then their weight remained at a stable level.

Were There Any Side Effects?

However, people's experience with the medication varied. Researchers found no unexpected safety issues with drug during trial. In fact, most the people who withdrew from the study were those who experienced the known symptsoms of the semaglutide injections like nausea, indigestion etc. This occurred mainly during the beginning of the study, as the dose of the medicine is increased to a maximally tolerated dose.

What Did The Results Say?

Of the people on the highest dose of Wegovy, 68% lost at least 5% of their body weight. This compared to 21% of people on the placebo. Additionally, of the total people on Wegovy about 23% lost at least 15% of their body weight. For those in the placebo group, only 1.7% lost that much body weight.

Semaglutide Shows Heart Benefits Beyond Weight Loss

Researchers found that even individuals who did not experience significant weight reduction while on the drug saw a reduced risk of major heart events. Recent analysis of the SELECT trial data revealed that semaglutide significantly lowers the risk of heart attack, stroke, and cardiovascular-related deaths in adults with obesity or those who are overweight. Notably, the results of this study lead the US FDA to approve Novo Nordisk's Wegovy for reducing heart-related risks in this group.

What Is Semaglutide?

Semglutide is the synthetic version of GLP-1—a natural hormone produced in the intestines that regulates blood sugar, appetite, and digestion. Now, every time you eat, your body produces various hormones, including GLP-1. These are called Post nutrition hormones, and help you absorb the energy you just consumed. GLP-1 travels to your pancreas, prompting it to produce insulin. It also travels to the hypothalamus in your brain, which gives you the feeling of being full or satiated. Ozempic imitates this hormone, thereby, silencing the food chatter in the brain. Interestingly, for some people this food chatter is really quiet ( people with low appetite) and for others it is an outburst, (people who generally binge eat.) So with Ozempic, silencing this self-talk in the brain, people tend to lose their appetite and eventually weight.

Are Their Any Side Effects Of Semaglutide?

Semaglutide, marketed under the brand name Wegovy, is primarily an antidiabetic medication used to treat Type 2 diabetes. It is also an anti-obesity drug used for long-term weight management. While it can be taken as a subcutaneous injection or orally, it has significant side effects. It primarily impacts your gastrointestinal tract and its side effects include constipation, nausea, abdominal pain, diarrhoea, and fatigue amongst others.

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The Hidden Health Cost Of Excessive Screen Time: Dry Eyes, Ringing Ears, Poor Sleep

Updated Sep 30, 2026 | 02:06 PM IST

SummaryExcessive screen time can contribute to dry eyes, disrupted sleep and tinnitus or ringing sensations, with prolonged device use affecting multiple aspects of health.
The Hidden Health Cost Of Excessive Screen Time: Dry Eyes, Ringing Ears, Poor Sleep

Credit: AI

It's hard to find anyone these days whose day doesn't involve a phone, a laptop, or a tablet at some point, often for several hours. We work off them, study off them, unwind by scrolling or watching something on them. All that convenience comes at a cost, though, and it isn't limited to the eyes. Sleep, hearing, posture, general well-being- screens end up touching all of it.

Long Screen Hours Can Strain Your Eyes

Eye strain is usually the first thing people notice. Stare at a screen close-up for long stretches, and the eyes start to dry out, burn, blur, and headaches creep in along with trouble focusing. Part of the problem is that we simply blink less when we're absorbed in something on a screen, which makes the dryness worse.

A few small adjustments help, keeping the screen at a reasonable distance, not having the brightness too high, and something I often recommend to patients: the 20-20-20 rule. Every 20 minutes, look at something roughly 20 feet away for 20 seconds. It sounds minor, but it eases the strain.

Also read: Salt Stomping Before Bed: Does This Viral TikTok Sleep Hack Actually Work?

Long Hours With Earphones Can Affect Hearing

Screens affect more than eyesight. Long hours spent wearing earphones, particularly at high volumes, can gradually affect hearing. The risk depends on both the volume and the duration of exposure.

Keeping the volume at a comfortable level and taking regular breaks from earphones is a simple enough habit to build. Persistent ringing in the ears, muffled hearing or difficulty following conversations should not be dismissed as fatigue and should be evaluated by a doctor.

Screen Use Can Disrupt Sleep

Sleep is one of the most overlooked casualties of excessive screen use. Phones and laptops used late at night keep the brain stimulated when the body should be winding down for rest. Bright light from screens, along with constant notifications, social media and work-related activity, makes it harder to unwind and fall asleep. Poor sleep, in turn, contributes to daytime fatigue, reduced concentration and irritability.

None of this means giving up technology altogether. It comes down to building healthier digital habits, avoiding screens close to bedtime, keeping phones away from the bed, taking regular movement breaks during work, and spending some time outdoors. For people working at computers for extended periods, maintaining good posture and changing position regularly matters just as much.

Also read: Weekend Workouts: Why Sudden Intense Exercise May Put Stress on Your Heart

There Is No Single ‘Safe’ Number Of Screen Hours

Clinical care today increasingly looks beyond treating disease to identifying everyday lifestyle factors that contribute to long-term health problems, and screen exposure is a good example of this. There isn't a single number of hours that is automatically harmful for every adult; the impact depends on what the screen is being used for, the intensity and duration of exposure, and whether it is interfering with sleep, physical activity or daily functioning.

Being screen-smart, rather than screen-free, is really the aim. Regular breaks, sensible volume levels, better sleep routines and more movement can go a long way in protecting the eyes, hearing and overall health, while still letting technology remain a useful part of modern life.

If symptoms such as persistent eye discomfort, hearing changes, recurrent headaches or ongoing sleep difficulties continue despite cutting down on screen time, it's worth seeking professional medical advice rather than relying on lifestyle adjustments alone.

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Salt Stomping Before Bed: Does This Viral TikTok Sleep Hack Actually Work?

Updated Sep 30, 2026 | 12:19 PM IST

SummaryTikTok’s latest sleep trend involves stomping barefoot on Epsom salt before bed, with creators claiming it can reduce stress, lower cortisol and improve sleep. But sleep experts say there is no scientific evidence that salt stomping provides these benefits, while the practice could irritate or damage the skin on your feet.
Salt Stomping: The Viral Sleep Trend Under Scrutiny

Salt stomping has gone viral as a bedtime ritual, with creators claiming it can improve sleep and reduce stress. Sleep experts, however, say there is no scientific evidence that standing on salt provides these benefits. (Image Credits: Instagram - @tamsskyn)

TikTok has a new sleep obsession every few months. Mouth taping, "cognitive shuffling," and now this: pouring salt onto a tray and stomping on it barefoot before bed. It's called "salt stomping," and doctors have doubts.

What Is Salt Stomping?

The trend was popularised by TikTok creator Tammy Weatherhead, who films herself pouring Epsom salt onto a baking sheet and shuffling her feet on it, according to the New York Post. "If you are not standing on salt before bed, you are missing out," she says in her videos. Other creators pour the salt onto baking sheets, towels or straight onto the shower floor, according to the New York Post.

The practice is framed as a type of "grounding," or direct contact with the earth, which some people normally do by walking barefoot on grass or sand, the New York Post notes. Weatherhead claims the salt version also exfoliates feet, reduces inflammation, and shifts the body into "rest mode" by lowering cortisol and raising serotonin.

Also Read: Heart Valve Clips Explained: How a Tiny Clip Can Help Repair a Leaking Valve

Does It Actually Work?

Doctors say no. Saema Tahir, a board-certified sleep physician, told the New York Post, "There's no evidence that standing on salt calms anything." IOL, a South African outlet, reported the same conclusion. There is currently no scientific evidence that standing directly on salt improves sleep.

There is some research on grounding in general, separate from salt. A small 2004 study published in the Journal of Alternative and Complementary Medicine found that people who slept in contact with a grounding mat had lower night-time cortisol levels. But the study didn't test salt, involved a small group of people, and hasn't been repeated at a larger scale since.

What might actually help is the ritual itself, not the salt. Jacqueline Geer, a sleep medicine specialist at Yale School of Medicine, told Vogue, as reported by Yahoo, that the benefit "lies in the fact that this trend requires a certain level of focus and disconnect" from a busy day. A psychologist identified as Dr. Bostock told the Huffington Post UK there's likely a placebo effect too: "If you believe something helps you sleep, the odds are you will fall asleep faster and stay asleep longer."

The Real Risk: Your Skin

Standing barefoot on salt can cause harm. Chris Winter, a neurologist and sleep specialist, told Vogue, as reported by Yahoo, that salt stomping can cause skin irritation, worsen cracks on the feet, and create small cuts that let bacteria into the body.

What To Do Instead

Sleep experts point to simpler, low-risk habits: calming, repetitive routines before bed that signal to the nervous system it's time to rest, per IOL. Geer's advice, per Yahoo, is to build in a period of focus and disconnection from screens and stress, rather than a specific trick. If anxiety is what's keeping you up at night, that's worth raising with a doctor directly, rather than testing viral hacks with no real evidence behind them.

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Heart Valve Clips Explained: How a Tiny Clip Can Help Repair a Leaking Valve

Health and Me

Updated Sep 30, 2026 | 11:00 AM IST

SummaryHeart valve clips can repair certain leaking valves without open-heart surgery by bringing valve leaflets together, reducing leakage and potentially improving symptoms and heart function.
Heart Valve Clips Explained: How a Tiny Clip Can Help Repair a Leaking Valve

Credit: AI

Heart clips—also referred to as heart valve clips—are part of a minimally invasive medical procedure known as Transcatheter Edge-to-Edge Repair (TEER). Designed to repair leaking heart valves without open-heart surgery, this advanced treatment restores proper blood flow, relieves debilitating symptoms, and helps patients return to their daily lives.

Understanding Valve Leakage and Symptoms

The heart's valves rely on thin flaps of tissue called leaflets to regulate blood flow.

  • The mitral valve (located on the left side of the heart) typically has two leaflets.
  • The tricuspid valve (located on the right side of the heart) usually consists of three leaflets.
Under normal conditions, these leaflets close tightly together every time the heart pumps. This seal prevents blood from flowing backward, ensuring it moves forward through the body rather than backing up into the lungs.

When a valve is leaking, the leaflets fail to close completely, leaving a gap. Blood leaks backward through this opening toward the lungs, increasing lung pressure and directly causing chronic breathlessness and fatigue.

Also read: 100% Blockage At 18, 25% Patients Under 40: On World Heart Day, Cardiologists Reveal An Alarming Heart Attack Pattern

How the Clip Repair Procedure Works

During a Transcatheter Edge-to-Edge Repair, cardiologists repair the valve using a tiny clip delivered through the vascular system:

  1. Catheter Access: Guided by continuous echo imaging, doctors insert a catheter into a blood vessel in the groin and navigate it directly to the heart.
  2. Targeting the Valve: The catheter goes to the left side of the heart for a mitral valve repair or to the right side for a tricuspid valve repair.
  3. Identifying the Leak: Imaging pinpoints the exact spot where the leaflets fail to seal.
  4. Deploying the Clip: The doctor positions and deploys the clip across the leaking gap, grasping the two opposing leaflets and pulling them closer together.
  5. Evaluating the Seal: Before releasing the clip completely, doctors perform an echocardiogram to confirm that the clip is strongly anchored, that the backward leak is fixed, and that the risk of clip detachment (embolization) is negligible.
Also read: World Heart Day: You Feel Healthy. But Plaque May Already Be Building In Your Arteries In Your 20s

Immediate Relief and Long-Term Healing

Once the clip brings the leaflets together, backward leakage stops immediately, allowing the entire volume of blood to pump forward as intended.

  • 24-Hour Recovery: Pressure inside the lungs drops rapidly once the leak is sealed. Many patients notice a dramatic improvement in their breathing within 24 hours of the procedure.
  • 3 to 6 Month Integration: Over a period of three to six months, surrounding heart tissue naturally grows over the clip (endothelialization), permanently integrating it into the heart structure.

Smooth Hospital Stay and Recovery

Because the procedure is catheter-based rather than open-chest, patient recovery is remarkably swift:

  • In-Room Extubation: Patients are taken off the ventilator right on the procedure table.
  • Minimal Closure Site: The groin entry point is closed cleanly using specialized sutures (such as ProGlide or a figure-of-eight suture).
  • Quick Discharge: Patients typically spend just one day in the Intensive Care Unit (ICU) before moving to a standard room, after which they can return home and resume normal daily activities.
By Dr. Ravinder Singh Rao, Interventional Cardiologist, Vice Chairman at RHL Rajasthan Hospital

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