People receiving weight-loss drug Wegovy sustained weight loss for up to four years, shedding an average of 10% of their body weight in that time, as per a new study. Wegrovy is a brand that markets semaglutide injections, that have gained widespread attention for their weight-loss effects. The study also found that Semaglutide injections boost an individual's heart health, even when weight loss doesn't take place.

The study, called SELECT, was published in journal Nature Medicine. "At four years, we see ongoing benefits of semaglutide," said Cheng-Han Chen, MD, interventional cardiologist from Cardiologist, who was not involved in the research. Besides the weight loss, it also lead to a loss in cardiovascular outcomes.

The research was conducted on 17000 adults, who had obesity but did not have diabetes. Overall, people who received once-weekly injections of semaglutide lost on average 10.2% of their body weight over the course of four years. All of the study participants continued to lose weight for about 65 weeks, a year and three months, and then their weight remained at a stable level.

Were There Any Side Effects?

What Did The Results Say?

Of the people on the highest dose of Wegovy, 68% lost at least 5% of their body weight. This compared to 21% of people on the placebo. Additionally, of the total people on Wegovy about 23% lost at least 15% of their body weight. For those in the placebo group, only 1.7% lost that much body weight.

Semaglutide Shows Heart Benefits Beyond Weight Loss

Researchers found that even individuals who did not experience significant weight reduction while on the drug saw a reduced risk of major heart events. Recent analysis of the SELECT trial data revealed that semaglutide significantly lowers the risk of heart attack, stroke, and cardiovascular-related deaths in adults with obesity or those who are overweight. Notably, the results of this study lead the US FDA to approve Novo Nordisk's Wegovy for reducing heart-related risks in this group.

What Is Semaglutide?

Are Their Any Side Effects Of Semaglutide?

Semaglutide, marketed under the brand name Wegovy, is primarily an antidiabetic medication used to treat Type 2 diabetes. It is also an anti-obesity drug used for long-term weight management. While it can be taken as a subcutaneous injection or orally, it has significant side effects. It primarily impacts your gastrointestinal tract and its side effects include constipation, nausea, abdominal pain, diarrhoea, and fatigue amongst others.

World Thyroid Day is observed on 25 May every year. This day aims to spread awareness about thyroid disorders, their symptoms, and management options that can help women. However, one concern that continues to linger with respect to thyroid disorders is why they occur more often in women. Hormonal changes, lifestyle factors, and a higher risk of autoimmune conditions can increase the risk of thyroid problems in women. Yes, that’s right! Hence, women should ensure they go for timely health check-ups. Here, an expert highlights vital tips for women. Read on to know more about this and seek timely help. Remember, thyroid problems should not be left untreated at all.

In an interview with Health and Me, Dr Shruti Kotangale, Consultant Gynaecologist, Obstetrician, and Infertility Expert at AIMS Hospital, Dombivli, explained why thyroid problems are more common among women. Read here to know how gender makes a difference.

Why do thyroid disorders occur more often in women?

Thyroid disorders are rising among many women. The thyroid is a small gland in the neck, but it plays a critical role in controlling metabolism, energy levels, and maintaining hormonal balance. Women can suffer from thyroid problems because of frequent hormonal changes during puberty, pregnancy, and menopause. These changes can impact thyroid health. Lifestyle factors such as stress, poor diet, and lack of sleep can also worsen thyroid imbalance. Hence, women are at a higher risk of suffering from autoimmune conditions, where the body’s immune system attacks the thyroid gland.

Hypothyroidism vs hyperthyroidism

Conditions such as hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) are commonly seen in women. Hypothyroidism occurs when the thyroid gland is underactive. Symptoms can include tiredness, weight gain, dry skin, hair fall, constipation, feeling cold, a slow heartbeat, and low mood or depression. Hyperthyroidism occurs when the thyroid gland becomes overactive, and women may experience weight loss, a fast heartbeat, sweating, anxiety, tremors, irritability, frequent bowel movements, and even difficulty sleeping. Women are advised to seek immediate medical attention and manage these symptoms without any further delay.

How to manage thyroid disorders?

Thyroid disorders may be concerning, but they are manageable with appropriate care and management tips as recommended by experts. Both hypothyroidism and hyperthyroidism can be managed with timely diagnosis, regular screening, and taking medications as suggested by the doctor. It is also important to eat a balanced diet, exercise daily for at least 30 minutes, get sound sleep at night, and de-stress through yoga and meditation. This World Thyroid Day, the focus should be on awareness, regular check-ups, and taking small steps to stay healthy and manage thyroid problems. Moreover, follow the doctor’s advice and do not self-medicate, as doing so can be risky.

So ladies, this World Thyroid Day, make an effort to know more about this group of disorders that affects your gender more often than men. Be it fatigue, mood swings, or weight fluctuations, it is imperative to know the early warning signs of this condition in order to work towards a more preventive approach.

IBD or Inflammatory Bowel Disease is a growing health concern worldwide - particularly amongst young adults. The two main types of IBD are Ulcerative Colitis and Crohn’s disease. However, these can be confused because they share symptoms.

Some of these are abdominal pain, diarrhea, fatigue, and weight loss. They affect the digestive tract differently, thus also have different complications and treatment plans. It is important to understand these differences so that patients may seek out timely diagnosis and better disease management.

1. Different Parts of the Digestive Tract Are Affected

Ulcerative Colitis is limited to the colon and rectum. Inflammation begins in the rectum and spreads continuously upwards. In Crohn’s disease, any part of the digestive system can be impacted. Including the mouth, esophagus, stomach, small intestine, and colon. However, it is most commonly the small intestine that is involved in Crohn’s disease.

2. Inflammation Pattern is Different

In ulcerative colitis, inflammation is continuous. There are no healthy gaps in between the affected areas. Crohn’s disease causes patchy inflammation. Meaning, there are sections of healthy tissue known as “skip lesions”.

3. Crohn’s Disease causes more serious damage

Ulcerative colitis affects only the innermost lining of the bowel. Crohn’s disease, on the other hand, can involve all layers of the intestinal wall. This increases the risk of complications such as fistulas, bowel obstruction, and intestinal narrowing.

4. Symptoms May Look Similar, But Often Differ

Both conditions can cause diarrhea, abdominal cramps, fatigue, and unintended weight loss. However, bloody stools are more common in ulcerative colitis. Crohn’s disease may also cause mouth ulcers, severe nutritional deficiencies, and pain in the anal region.

5. Nutritional Problems Are More Common in Crohn’s Disease

Because Crohn’s disease frequently affects the small intestine, patients may struggle to absorb nutrients properly. This struggle results in anemia, a vitamin B12 deficiency, low iron levels, and weight loss.

6. Surgery Has Different Outcomes

Ulcerative colitis can be cured by removing the colon. In Crohn’s disease, surgery is used mainly to treat complications, but inflammation can affect another part of the digestive tract.

7. Smoking Affects the Diseases Differently

Smoking worsens Crohn’s disease. It increases the risk of flare-ups, complications, as well as repeat surgeries. However, Ulcerative Colitis does not show the same pattern. Some studies have found lower rates of ulcerative colitis among smokers. Although smoking is never recommended as a treatment because of its serious health risks.

8. Treatment Approaches

Both conditions are treated with anti-inflammatory medications, immunosuppressing drugs, and dietary changes. But in Crohn’s disease, often more aggressive and long-term treatment is required. This is because it can affect the deeper layers of the bowel and multiple parts of the digestive tract.

Most people who hear the words “robotic surgery” picture something from a science fiction film. A machine operating independently, the surgeon watching from across the room. The reality is considerably less dramatic and considerably more reassuring.

In robotic-assisted surgery, the surgeon is in control throughout the procedure. The robotic system does not make independent decisions. It functions as a precision instrument, translating the surgeon’s movements into actions with a degree of accuracy that is difficult to achieve through conventional techniques alone. A useful parallel is GPS navigation — the driver still steers, still makes every turn, still decides the route. The technology makes the execution more reliable.

What this means for patients, practically, is a procedure designed to do what it needs to do with less disruption to the surrounding tissue. Less disruption means less post-operative pain. Less pain means rehabilitation begins sooner. And sooner rehabilitation means the things patients actually care about — walking without discomfort, climbing stairs, travelling, returning to work — come back faster.

This is why robotic surgery has gained traction in orthopedics in particular. Joint replacement patients are not looking for a technical achievement. They are looking to move again. They want to walk to the kitchen without wincing, attend a family function without sitting out the evening, and pick up their grandchildren. The recovery is the point, and the precision that robotic assistance enables is what makes that recovery more predictable.

There are persistent myths worth addressing directly. That robotic surgery is risky because it relies on machines — it is not, because the surgeon remains in control and the system includes multiple real-time safety checks. That it is only accessible in premium or specialty settings — increasingly, it is not. That the higher upfront cost cannot be justified — for many patients, the shorter hospital stay, lower post-operative pain, and reduced likelihood of complications make the calculus straightforward.

Healthcare is moving toward precision and personalization, and patients are moving with it. The question most people are now asking before surgery is not only whether the procedure will work. It is how quickly and how fully they will get their life back afterward. Robotic-assisted surgery was built to answer that question.