Wegovy Users Maintain Weight Loss for 4 Years: Here's How It Works

Updated Dec 3, 2024 | 09:00 PM IST

SummaryWegovy, is primarily an antidiabetic medication used to treat Type 2 diabetes. People receiving weight-loss drug Wegrovy sustained weight loss for up to four years
wegovy

wegovy (Credit: Canva)

People receiving weight-loss drug Wegovy sustained weight loss for up to four years, shedding an average of 10% of their body weight in that time, as per a new study. Wegrovy is a brand that markets semaglutide injections, that have gained widespread attention for their weight-loss effects. The study also found that Semaglutide injections boost an individual's heart health, even when weight loss doesn't take place.

The study, called SELECT, was published in journal Nature Medicine. "At four years, we see ongoing benefits of semaglutide," said Cheng-Han Chen, MD, interventional cardiologist from Cardiologist, who was not involved in the research. Besides the weight loss, it also lead to a loss in cardiovascular outcomes.

The research was conducted on 17000 adults, who had obesity but did not have diabetes. Overall, people who received once-weekly injections of semaglutide lost on average 10.2% of their body weight over the course of four years. All of the study participants continued to lose weight for about 65 weeks, a year and three months, and then their weight remained at a stable level.

Were There Any Side Effects?

However, people's experience with the medication varied. Researchers found no unexpected safety issues with drug during trial. In fact, most the people who withdrew from the study were those who experienced the known symptsoms of the semaglutide injections like nausea, indigestion etc. This occurred mainly during the beginning of the study, as the dose of the medicine is increased to a maximally tolerated dose.

What Did The Results Say?

Of the people on the highest dose of Wegovy, 68% lost at least 5% of their body weight. This compared to 21% of people on the placebo. Additionally, of the total people on Wegovy about 23% lost at least 15% of their body weight. For those in the placebo group, only 1.7% lost that much body weight.

Semaglutide Shows Heart Benefits Beyond Weight Loss

Researchers found that even individuals who did not experience significant weight reduction while on the drug saw a reduced risk of major heart events. Recent analysis of the SELECT trial data revealed that semaglutide significantly lowers the risk of heart attack, stroke, and cardiovascular-related deaths in adults with obesity or those who are overweight. Notably, the results of this study lead the US FDA to approve Novo Nordisk's Wegovy for reducing heart-related risks in this group.

What Is Semaglutide?

Semglutide is the synthetic version of GLP-1—a natural hormone produced in the intestines that regulates blood sugar, appetite, and digestion. Now, every time you eat, your body produces various hormones, including GLP-1. These are called Post nutrition hormones, and help you absorb the energy you just consumed. GLP-1 travels to your pancreas, prompting it to produce insulin. It also travels to the hypothalamus in your brain, which gives you the feeling of being full or satiated. Ozempic imitates this hormone, thereby, silencing the food chatter in the brain. Interestingly, for some people this food chatter is really quiet ( people with low appetite) and for others it is an outburst, (people who generally binge eat.) So with Ozempic, silencing this self-talk in the brain, people tend to lose their appetite and eventually weight.

Are Their Any Side Effects Of Semaglutide?

Semaglutide, marketed under the brand name Wegovy, is primarily an antidiabetic medication used to treat Type 2 diabetes. It is also an anti-obesity drug used for long-term weight management. While it can be taken as a subcutaneous injection or orally, it has significant side effects. It primarily impacts your gastrointestinal tract and its side effects include constipation, nausea, abdominal pain, diarrhoea, and fatigue amongst others.

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Summer Heat Triggers Viral Gastroenteritis Cases in Mysuru: Know How To Prevent Stomach Flu

Updated Apr 13, 2026 | 09:45 AM IST

SummaryThe India Meteorological Department has warned of rising heat and humidity across Coastal Karnataka until April 12. ​​The IMD has advised people to stay well hydrated and take precautions while stepping outdoors. Residents are also urged to avoid prolonged exposure to the sun during peak hours.
Summer Heat Triggers Viral Gastroenteritis Cases in Mysuru: Know How To Prevent Stomach Flu

Credit: Canva

The southern Indian state of Karnataka, currently reeling under intense summer heat, has been experiencing an outbreak of viral gastroenteritis over the past few weeks, according to media reports.

Due to the scorching heat, doctors in Mysuru flagged a 15-20 per cent rise in patients with gastrointestinal complaints, Deccan Herald reported.

According to Dr A. K. Satheesh Rao, senior consultant in medical gastroenterology and hepatology, the early arrival of summer with higher intensity across Mysuru and surrounding regions is driving the cases.

“The prolonged spells of heat and rising temperatures are impacting stomach and digestive health. Over the past few weeks, we have seen about a 15-20 per cent increase in patients with gastrointestinal complaints like frequent episodes of vomiting, abdominal discomfort, rapid dehydration, and diarrhea. Another major concern is a rise in dehydration,” he said.

“Although such seasonal spikes are expected, this year the intensity and frequency of symptoms are concerning, as a majority of the cases are being diagnosed as viral gastroenteritis. Just like any other viral infection, viral gastroenteritis is transmissible through contaminated food and water,” Dr. Rao added.

Meanwhile, the India Meteorological Department (IMD) has issued a warning of rising heat and humidity across Coastal Karnataka until April 12.

Districts like Dakshina Kannada, Udupi, and Uttara Kannada are expected to experience hot weather with high atmospheric moisture. Such weather can lead to fatigue and discomfort, particularly among the elderly, children, and those with existing health conditions.

The IMD has advised people to stay well hydrated and take precautions while stepping outdoors. Residents are also urged to avoid prolonged exposure to the sun during peak hours.

What Is Gastroenteritis?

Commonly referred to as the stomach flu, gastroenteritis is another illness that tends to spike in the fall.

Caused by viruses like norovirus, this condition leads to inflammation of the stomach and intestines. While gastroenteritis is typically short-lived, it can be particularly uncomfortable and disruptive.

Common symptoms include:

  • Nausea and vomiting – More common in children than adults.
  • Watery diarrhea – May cause dehydration if not well taken care of.
  • Stomach cramps and pain – Usually intense and sudden.
  • Mild fever and body aches – May be confused with flu.
  • Sudden development of illness – Symptoms develop 24-48 hours after exposure and persist 1-3 days.

Gastroenteritis can affect children more intensely. Dehydration is the most immediate threat posed by stomach flu, particularly among infants and young children. As children quickly lose fluids from diarrhea and vomiting, parents must observe warning symptoms of severe dehydration, such as:

  • Dry mouth and tongue
  • Decreased urine output (fewer wet diapers in an infant)
  • Not crying tears
  • Sunken soft spot on the top of a baby's head (fontanelle)
  • Irritability, drowsiness, or lethargy.
If your child shows these signs, get them to the doctor right away.

How To Prevent

Hydrating oneself with portable water, eating healthy food, and maintaining hand hygiene are important.

“Simple practices like proper water storage, drinking filtered or boiled and cooled water, opting for home-cooked and freshly prepared meals, and basic hand hygiene serve as powerful safeguards,” Dr Rao said.

Further, one should also follow essential hygiene practices, including:

1. Practice frequent handwashing

2. Clean high-touch surfaces

3. Safe food handling

4. Keep sick children at home.

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Cancer-Hit US Couple Opens Up On ‘Nightmare’ Experience

Updated Apr 13, 2026 | 11:28 AM IST

SummaryWhile Spencer Eddy’s dizzy spells were diagnosed as medulloblastoma, his wife Jolene’s pea-sized lump under her armpit was found to be breast cancer. The parents of three children struggled through their cancer journey and now have no evidence of cancer.
Cancer-Hit US Couple Opens Up On ‘Nightmare’ Experience

Credit: Canva

A Cancer-hit US couple in North Dakota has shared their ‘nightmare’ experience with dual diagnosis of the deadly disease and parenting their three children.

Spencer Eddy, a 39-year-old father of three, suffered from dizzy spells for years. While doctors dismissed the condition as vertigo, it turned out to be a brain tumor, People reported.

MRI scans in April 2024 revealed that he had a tumor the size of a lime in his brain. Further scans and tests at Mayo Clinic in October confirmed medulloblastoma -- a malignant tumor that is located on the part of the brain that controls coordination and movement.

According to the Mayo Clinic, it is most common in children, but can occur in adults.

“When we found out that Spencer had a brain tumor, we were terrified,” said Jolene, his wife. “They said the cancer was blocking the fluid that flows from your vein to your spinal cord. They said they didn't know how he was still walking and talking, and how he hadn't had a stroke."

A week later, Spencer underwent a 10-hour surgery, and doctors were able to remove 85 percent of the tumor. Along with radiation and chemotherapy, he also needed speech and physical therapy to relearn how to walk and talk, People reported.

What came as a double blow to the couple was Jolene’s breast cancer diagnosis in April 2025.

“Whilst we were in the hospital, I noticed a small pea-sized lump under my armpit, but I put it to the back of my mind, because of everything that was going on with Spencer,” she recalled. “Doctors said it was probably just a cyst, but I asked for it to be removed anyway, and when it came back from testing, I found out it was breast cancer. I was absolutely floored.”

The doting parents “were so devastated and scared about what would happen to their kids”, if both of them die.

Following her diagnosis, Jolene was given hormone blockers and underwent a double mastectomy while Spencer was still undergoing chemotherapy.

Jolene struggled after the surgery and was vomiting and passing out frequently. She ultimately needed a blood transfusion and was able to recover.

It was hard for Jolene to take care of the family as Spencer could not walk well or drive.

"We're living most people's nightmare, but we're feeling optimistic about the future,” she said. “We have a long life, and we're going to fight for it; we're not going to give up.”

Spencer completed treatment in April 2025 and now has no evidence of cancer. Jolene also has no evidence of cancer. The couple now goes to appointments with their oncologists together as they hope to ensure their tumors don't grow back, the report said

Can A Brain Tumor Cause Dizziness?

While dizziness by itself is not a common symptom of a brain tumor, some tumors can trigger headaches and bouts of nausea and vomiting that may be associated with a dizzy feeling.

Dizziness, also called vertigo, is however, associated with tumors that develop in the cerebellum—the part of the brain that controls movement.

Medulloblastoma, a type of brain tumor, forms when cells in the cerebellum develop changes in their DNA. These changes cause the cells to grow and multiply quickly, as per the Mayo Clinic.

Common signs and symptoms of medulloblastoma may include:

  • Dizziness.
  • Double vision or other vision changes.
  • Headaches, which are often worse in the morning.
  • Nausea or vomiting.
  • Poor coordination.
  • Tiredness.
  • Difficulty with balance or an unsteady walk.

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Is Chest Pain The Only Sign Of Heart Disease?

Updated Apr 12, 2026 | 06:00 PM IST

SummaryMost people think that only chest pain and tightness are signs of heart disease. However, there are several other silent symptoms. This, and many other myths associated with heart diseases, was debunked by a cardiologist.
chest pain

Not just chest pain, but even jaw pain can be associated with heart disease. (Photo credit: iStock)

There are many myths linked to heart health that can mislead people and prevent them from seeking timely help. This article helps to debunk the myths and keep the heart healthy. It is time to prioritize heart health. Dr Rahul Gupta, Director of Interventional Cardiology and Structural Heart Program, Gleneagles Hospital, Parel, Mumbai, spoke about the common myths about heart disease and listed the facts as well.

Heart problems are commonly seen in people of all age groups. However, heart health is often surrounded by myths and misconceptions that can lead to confusion and poor lifestyle choices in people. So, heart health depends on multiple factors, including diet, activity, stress, and overall lifestyle, and not just one or two habits. Here, the expert helps to debunk the myths associated with heart health and improve the quality of life.

Dispelling myths surrounding heart health

Myth 1: Only older people are at risk of heart problems

Fact: People commonly believe that heart problems can only happen in old age. However, currently, a large number of youngsters aged 25-35 are also struggling with heart issues such as heart attacks and heart failure because of stress, unhealthy diets, and lack of exercise. So, heart problems are not limited only to older people. Anyone, irrespective of their age, can suffer from them. Hence, there is a need of the hour to go for regular heart check-ups and to initiate timely treatment for heart problems.

Myth 2: If you are fit, your heart is SAFE

Fact: So, being physically active is important, but it does not reduce the chances of heart problems. Be attentive to the family history, genetics, and other factors such as high cholesterol or even stress. So, go for cardiac screening on a yearly basis to know the status of your heart health. Discomfort in the arms, jaw, or back and light-headedness can also mean that your heart is in danger.

Myth 3: Heart disease is only seen in men

Fact: Shockingly, heart disease also causes higher morbidity and mortality rates in women. The symptoms seen in women linked to heart disease are dizziness, palpitations, and even giddiness. Hence, women should also focus on their heart health. Stay alert, stay safe!

Your heart health matters. By understanding the facts and making informed choices, it is possible for everyone to protect their heart and overall well-being.

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