Wegovy Users Maintain Weight Loss for 4 Years: Here's How It Works

Updated Dec 3, 2024 | 09:00 PM IST

SummaryWegovy, is primarily an antidiabetic medication used to treat Type 2 diabetes. People receiving weight-loss drug Wegrovy sustained weight loss for up to four years
wegovy

wegovy (Credit: Canva)

People receiving weight-loss drug Wegovy sustained weight loss for up to four years, shedding an average of 10% of their body weight in that time, as per a new study. Wegrovy is a brand that markets semaglutide injections, that have gained widespread attention for their weight-loss effects. The study also found that Semaglutide injections boost an individual's heart health, even when weight loss doesn't take place.

The study, called SELECT, was published in journal Nature Medicine. "At four years, we see ongoing benefits of semaglutide," said Cheng-Han Chen, MD, interventional cardiologist from Cardiologist, who was not involved in the research. Besides the weight loss, it also lead to a loss in cardiovascular outcomes.

The research was conducted on 17000 adults, who had obesity but did not have diabetes. Overall, people who received once-weekly injections of semaglutide lost on average 10.2% of their body weight over the course of four years. All of the study participants continued to lose weight for about 65 weeks, a year and three months, and then their weight remained at a stable level.

Were There Any Side Effects?

However, people's experience with the medication varied. Researchers found no unexpected safety issues with drug during trial. In fact, most the people who withdrew from the study were those who experienced the known symptsoms of the semaglutide injections like nausea, indigestion etc. This occurred mainly during the beginning of the study, as the dose of the medicine is increased to a maximally tolerated dose.

What Did The Results Say?

Of the people on the highest dose of Wegovy, 68% lost at least 5% of their body weight. This compared to 21% of people on the placebo. Additionally, of the total people on Wegovy about 23% lost at least 15% of their body weight. For those in the placebo group, only 1.7% lost that much body weight.

Semaglutide Shows Heart Benefits Beyond Weight Loss

Researchers found that even individuals who did not experience significant weight reduction while on the drug saw a reduced risk of major heart events. Recent analysis of the SELECT trial data revealed that semaglutide significantly lowers the risk of heart attack, stroke, and cardiovascular-related deaths in adults with obesity or those who are overweight. Notably, the results of this study lead the US FDA to approve Novo Nordisk's Wegovy for reducing heart-related risks in this group.

What Is Semaglutide?

Semglutide is the synthetic version of GLP-1—a natural hormone produced in the intestines that regulates blood sugar, appetite, and digestion. Now, every time you eat, your body produces various hormones, including GLP-1. These are called Post nutrition hormones, and help you absorb the energy you just consumed. GLP-1 travels to your pancreas, prompting it to produce insulin. It also travels to the hypothalamus in your brain, which gives you the feeling of being full or satiated. Ozempic imitates this hormone, thereby, silencing the food chatter in the brain. Interestingly, for some people this food chatter is really quiet ( people with low appetite) and for others it is an outburst, (people who generally binge eat.) So with Ozempic, silencing this self-talk in the brain, people tend to lose their appetite and eventually weight.

Are Their Any Side Effects Of Semaglutide?

Semaglutide, marketed under the brand name Wegovy, is primarily an antidiabetic medication used to treat Type 2 diabetes. It is also an anti-obesity drug used for long-term weight management. While it can be taken as a subcutaneous injection or orally, it has significant side effects. It primarily impacts your gastrointestinal tract and its side effects include constipation, nausea, abdominal pain, diarrhoea, and fatigue amongst others.

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Experts Warn Why You Should Pay Attention To Baby Food Labels

Updated Feb 19, 2026 | 06:12 PM IST

SummaryPackaged baby foods often contain hidden sugars and industrial additives that can harm long term baby's health. To ensure optimal development, prioritize nutrient dense whole foods or single ingredient products over ultra processed snacks
Experts Warn Why You Should Pay Attention To Baby Food Labels

Credit: My Pedia Clinic

Many packaged baby foods marketed as healthy may contain hidden sugars and ultra-processed ingredients that can shape a child’s taste preferences and long-term health.

Brightly packaged baby cereals, fruit pouches, snack puffs and flavored yoghurts use “natural”, “organic” and “doctor recommended” labels to advertise their nutritional value and reassure parents.

“What shocked me was the top ingredient in 71% of these baby foods wasn’t a fruit or vegetable, it was one or more additives,” said Dunford, who is also a consultant at The George Institute for Global Health.

However, packaged baby food is instead packed with artificial additives and highly processed components such as carrageenan, xanthan and guar gum.

Why Ultra Processed Baby Foods?

The majority of packaged baby foods are classified as ultraprocessed because they undergo extensive industrial manufacturing and contain ingredients rarely found in a home kitchen.

Rather than using whole, simple foods, many manufacturers rely on heavy processing steps that strip away natural nutrients.

Key Indicators of Ultra Processed Food

Refined Bases: Many ready-to-eat snacks, like puffs, use refined starches and flours as their primary ingredients instead of whole grains.

Not Real Whole Fruit: Many brands often claim whole fruit however; they only provide taste and sweetness without the beneficial fiber and nutrients of the original fruit.

Hidden Sugars and Fillers: Products like flavored cereals frequently contain maltodextrin, added sugars and flavor enhancers to improve palatability.

Industrial Additives: To ensure shelf stability and consistent texture, these foods are often loaded with stabilizers, preservatives, and emulsifiers.

Which Additives That Parents Should Know About?

Even when a product claims to have "no added sugar," it can still be packed with sweeteners. Manufacturers frequently use fruit juice concentrates, corn syrup solids and glucose-based ingredients to enhance flavor.

These concentrated sugars train a baby’s developing palate. Early exposure to intense sweetness can create a lifelong preference for sugary foods, increasing the risk of poor dietary habits in adulthood.

2. "Natural Flavors"

The term "natural flavor" is often misunderstood. While the origin of the flavor must be a natural source, the final additive is often heavily modified in a laboratory.

These substances are engineered to make processed food taste more appealing than it naturally would, which can distort a child's appreciation for the taste of whole, fresh foods.

3. Stabilizers and Gums

To ensure a product looks perfect after sitting on a shelf for months, companies add stabilizers and industrial gums.

These additives create a permanent, uniform texture that prevents the food from separating or changing consistency during storage.

How To know If Baby Food Is Ultra Processed?

Check first three ingredients: Ingredients are listed by weight. If refined flour, fruit concentrates, or syrups appear in the top three, the product is highly processed.

Hidden sweeteners: Sweeteners like dextrose, glucose syrup, malt extract, and corn solids are just fancy names for Sugar.

Go For Shorter lists: Avoid long lists of chemical sounding names.

Why Does Early Nutrition Matter?

Critical Development Window: Infancy is the primary period for both physical growth and brain maturity.

Nutritious food: Babies require high nourished foods high in vitamins, minerals, healthy fats, and proteins rather than just calories.

Freshness: Fresh consistently provide higher levels of essential nutrients compared to any packaged or processed product.

Palate Programming: This stage establishes a child’s lifelong food habits. Processed baby foods can systematically eliminate whole food choices by training the child to prefer artificial textures and flavors.

Adulthood: Early nutrition is a key pillar of foundational health; the quality of food a baby eats now sets the biological template for their health in adulthood.

How To Give Baby Nutritional Food?

Homemade food: Cooking at home allows for complete management of every ingredient, ensuring no hidden additives or preservatives enter your baby's diet.

Natural Choices: Simple combinations such as mashed fruits, steamed vegetables, dal, khichdi, and curd provide essential nutrients without artificial components.

Minimal Processing: If buying packaged, choose single-ingredient products, plain vegetable purees or unsweetened cereals to avoid hidden flavors.

NOTE: A shorter ingredient list is always the safest and healthiest choice for your child.

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Experts Claim Men Can Also Develop Endometriosis, Here's Why

Updated Feb 19, 2026 | 06:07 PM IST

SummaryEndometriosis can affect men when Müllerian duct remnants embryonic tissues present in both sexes are reactivated. The condition is triggered by high estrogen levels from obesity, liver issues or prostate treatments
Experts Claim Men Can Also Develop Endometriosis, Here's Why

Credit: Freepik

Endometriosis is traditionally defined by the presence of tissue similar to the lining of the uterus, the endometrium growing in locations where it doesn't belong, such as the fallopian tubes, ovaries and pelvic cavity.

Since this tissue is hormonally responsive, it bleeds and causes inflammation during a menstrual cycle.

While experts have long categorized this as a condition solely affecting women, rare clinical cases have shattered this assumption and revealed that the biological blueprint for endometriosis exists in the male body

as well.

What Causes Endometriosis?

There is no exact cause of endometriosis, but possible causes include:

  • Retrograde menstruation: Fallopian tubes and into the pelvic cavity instead of out of the body. These cells may stick themselves to the inner pelvic lining and organs from where they multiply.
  • Transformed peritoneal cells. Hormones or immune factors might transform cells that line the inner side of the abdomen, called peritoneal cells, into cells that are like those that line the inside of the uterus.
  • Embryonic cell changes. Hormones such as estrogen may transform embryonic cells in the earliest stages of development into endometrial-like cell growths during puberty.
  • Surgical scar complication. Endometrial cells may attach to scar tissue from a cut made during surgery to the stomach area, such as a C-section.
  • Endometrial cell transport. The blood vessels or tissue fluid system may move endometrial cells to other parts of the body.
  • Immune system condition. A problem with the immune system may make the body unable to recognize and destroy endometriosis tissue.

What Are Symptoms Of Endometriosis?

  • Severe Abdominal Pain
  • Bloating
  • Painful periods
  • Pain with sex
  • Pain with bowel movements or urination.
  • Excessive bleeding
  • Infertility
  • Fatigue
  • Diarrhea
  • Constipation
  • Nausea

How Does Endometriosis Develop In Men?

When fertilization occurs, both sexes develop Müllerian Ducts. These ducts are paired tubes that grow into female reproductive organs early in fetal development.

They help in the formation of the uterus, cervix, fallopian tubes and upper vagina. However, men develop the Anti Mullerian Hormone, also known as AMH which regresses the formation of these ducts.

Men can develop the ducts when exposed to estrogen. Typically, those who are undergoing prostate cancer treatment, hormone replacement therapy or suffering from obesity take estrogen.

Consistent exposure to estrogen can actually transform those inactive cells or remnants of Mullerian Ducts into endometriosis tissues and pave the way for the development of the disease.

How Common Is Endometriosis?

A study reveals that nearly 43 million women globally, out of which, nearly 10 percent of Indian women suffer from endometriosis.

While the disease is almost diagnosed in women, documented cases in men confirm that they hold the biological potential to develop endometriosis.

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Christy Carlson Romano’s Cancer Test Result Shows Why Regular Screening Is Important

Updated Feb 19, 2026 | 06:00 PM IST

SummaryChristy Carlson Romano's positive cancer screening has reiterated the need for increasing awareness about regular screenings. As studies show an increase in early onset of cancers among women, tests like mammograms and Pap smears can be crucial in detecting deadly tumors early, when treatment is most effective.
Christy Carlson Romano’s Cancer Test Result Shows Why Regular Screening Is Important

Credit: Instagram

American actress Christy Carlson Romano’s shocking announcement of a positive cancer screening test has reignited the debate on the rising early onset of cancers among women, as well as the importance of early screening.

Cancer is everywhere, said Romano, 41, in a tearful video on social media platform Instagram.

The former Disney star noted that she underwent cancer screenings, along with her husband, Brendan Rooney, as her family has a history of cancer.

“My husband’s came back completely negative,” she said, adding, “Mine did not come back negative. So basically, what that means is that I may have stageable cancer.”

The ‘Even Stevens’ star shared that she next aims to get a PET scan, which will help her gauge the stage of the cancer.

Early-onset Cancers Rising Among Women Under 50

While the news of Romano's positive cancer test has left fans shocked, it also highlights the fact that cancer is increasingly shifting its attack to women under 50.

A 2025 study by Duke Cancer Institute in the US revealed that for women younger than 50, the risk of developing cancer is 82 percent higher than that of men, up from 51 percent in 2022.

The 2025 annual report from the American Cancer Society (ACS) also showed that cancer rates in young and middle-aged women are rising past those of men in the same age group, but especially among women under age 50.

While breast cancer has emerged as the most common among women under 50, it is followed by thyroid cancer, melanoma, and skin cancers. Cervical cancer, ovarian cancer, and colorectal cancer are other names. Uterine cancer, also known as endometrial cancer, is also killing more women than ever.

Notable names include Princess of Wales Kate Middleton, who was 42 when she announced her cancer diagnosis two years back. American actress Olivia Munn reported a breast cancer diagnosis at the age of 43.

Similarly, Indian actress Sonali Bendre was 46 years old when diagnosed with high-grade metastatic cancer in July 2018. Others with young cancer onset include Hina Khan, Chhavi Mittal, Dipika Kakkar, and Tahira Kashyap. Young TV actresses Dolly Sohi and Priya Marathe reportedly succumbed to cancer.

According to studies, besides genetic factors, increased intake of highly processed foods, sugary beverages, lack of exercise, the surge in stress levels, exposure to air pollution, microplastics, and mindless intake of antibiotics, and even increased screen time are major contributors to the deadly disease.

Other possible risk factors include alcohol consumption, sleep deprivation, smoking, and obesity.

Why Is Early Screening Important?

Late diagnosis is a major driver of cancer deaths. On the contrary, early screening can help detect changes in the body's cells before cancer develops and spreads.

It can also help in cancers, which present no symptoms until the late stage.

It not only improves survival rates but also helps with less invasive and more effective treatments.

Regular screening measures include mammograms, Pap smears, colonoscopies, Low-dose CT Scans, and PSA tests, which reduce mortality by identifying cancer at early and manageable stages, preventing its progression and the risk of death.

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