A new report published in The Lancet Diabetes & Endocrinology challenges the conventional definition of obesity, and urges a shift from the reliance on Body Mass Index (BMI) to a more nuanced approach. This is supported by over 50 global medical experts. The report also recommends splitting the term "obesity" into two categories: "Clinical obesity" and "Pre-clinical obesity". This aims to improve diagnosis and treatment for over a billion people worldwide living with obesity.
This applies to individuals whose obesity has progressed to a disease state, manifesting in organ damage, heart disease, type 2 diabetes, or other health complications. These individuals could also experience symptoms like breathlessness, joint pain, or impaired daily functioning. Treatment also involves medical interventions, including weight-loss medications or surgery.
Whereas the term "pre-clinic obese" refers to those who are overweight but not yet exhibiting health issues. While they may be at risk of developing obesity-related conditions, their organ function and overall health remain intact. What they need is preventive care, which includes dietary guidance, counselling, and regular monitoring to avoid and reduce future health risks.
The study, led by Professor Francesco Rubino from King's College London emphasizes that obesity is not one-size-fits-all condition. This means it should rather be treated as a spectrum as some individuals maintain normal organ function despite being classified as obese. There are others who may face severe health complications too. However, the current method of calculating obesity based on BMI often leads to misdiagnosis or inadequate care.
The report also states that BMI, while is useful for analyzing population trends, is a flawed unit of measuring individual health. Therefore, there is a need to redefine obesity, and healthcare professionals can provide more precise care by distinguishing those who need immediate medical intervention and those who require preventive strategies.
BMI is used to classify individuals as underweight, healthy weight, overweight, or obese based on their height and weight. It is calculated by dividing weight in kilograms by health in meters squared. However, there are reasons while it falls short.
•Muscle vs Fat: Athletes or muscular individuals often have high BMIs despite the low body fat
•Fat Distribution: BMI does not measure fat around the waist or organs, which could be more dangerous to one's health.
•Individual Health Variation: It also overlooks the specific health conditions such as heart diseases or diabetes, or any other, while evaluating a person's category in terms of weight.
ALSO READ: Is It Time To Say Goodbye To BMI?
By redefining obesity, the study could transform the approach to diagnosis and treatment. It can focus on individual health risks rather than BMI alone. Healthcare providers can also offer tailored care. This also will ensure hat weight-loss medications like Wegovy or Mounjaro are prescribed only to those who genuinely require it.
As per Professor Louise Baur from the University of Sydney, a Children's obesity expert said that this redefinition allows both adults and children to receive more appropriate care while reducing over-diagnosis and unnecessary treatments.
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The boom in GLP-1 weight loss drugs is not only affecting the obesity market but also reshaping the beauty industry. Changes in consumer behaviour among those who use GLP-1 drugs is evident as people may see differences in their appearance after drastic weight loss. This phenomenon has prompted global beauty companies to explore products for people experiencing changes in their appearance after losing weight.
French cosmetics giant L’Oréal is among the companies exploring this emerging market segment. Its CEO, Nicolas Hieronimus, said the increasing use of these medications was affecting beauty and skincare consumption, compelling the company to explore products that address concerns like sagging skin after extreme weight loss.
“The rise in their (GLP-1 drugs) use was having an impact on beauty consumption and skin care consumption in particular,” Hieronimus said during an investor call on October 22, after the company's third-quarter results came out.
The development mirrors an important shift in the beauty industry as weight loss medications like Ozempic, Wegovy and Zepbound become more widely used for weight management.
Amid the growing market for these drugs, companies are now seeing increased demand for treatments that help changes in facial volume, skin firmness and elasticity after weight loss.
However, the science behind ‘Ozempic face’ is far more complicated than the name suggests. Experts say these changes are generally associated with losing facial fat during weight loss, especially when it happens rapidly.
‘Ozempic face’ is an informal term for facial changes that occur after rapid and substantial weight loss. It is marked by hollowing around the cheeks and temples and more noticeable wrinkles or sagging skin.
GLP-1 medicines, including semaglutide and tirzepatide, act on appetite regulation, helping people feel fuller for a long time and reducing their calorie intake. As a result, some people lose a substantial amount of weight over a short period.
Apart from L’Oréal, Swiss skincare company Galderma and Brazilian cosmetics group Natura are also seeing similar demands from consumers experiencing changes in their facial skin after medicated weight loss.
L’Oréal has said that it is testing products on people using GLP-1 medications. Its SkinCeuticals range also has products intended to address concerns such as skin sagging, according to Hieronimus.
“We have products in SkinCeuticals that are made to work alongside GLP-1 drugs and address their side effects, such as skin sagging and other related issues. It is very integrated,” he said.
Galderma, in which L’Oréal holds a 20% stake, has assessed some of its existing aesthetic treatments for changes due to GLP-1 use. Its portfolio includes Sculptra, an injectable that stimulates collagen, and Restylane, a range of hyaluronic acid-based dermal fillers.
Anne-Cecile Chevrier, Galderma's global head of injectable aesthetics, described the concerns that experts are seeing among consumers. “Sagginess is a concern, loss of firmness is a concern, some hollowness can be of concern and dullness can be a concern,” she said.
The expansion of this market does not necessarily mean that skincare products can reverse facial changes due to rapid weight loss.
The skin has several layers, and topical products act on the skin's surface. Facial fat loss happens when fat accumulated beneath the skin melts off. Skincare products cannot simply replace this process.
Dr Graeme Glass, a plastic and craniofacial surgeon and aesthetic director at British beauty brand LYMA, explained the limitations of topical treatments. “They can't reposition the deep fat pads of the face. There is a limit to what these things can do,” he said.
Moisturisers and other products may help improve hydration, texture and the appearance of fine lines. But these benefits should not be confused with correcting sagging skin.
Treatments like fillers and collagen injectables may address these concerns directly, but they involve different risks, costs and clinical considerations.
Avani Sinha, MD, and FACE endocrinologist and program director of the Northwell Health Division of Endocrinology, Diabetes and Metabolism fellowship told Women's Health Magazine that it is important to take care of nutrition and muscle-building to "fill up spaces where you are losing that skin laxity".
“We are what we eat, we are what we do,” she said, stating that protein intake is especially important on a GLP-1. She suggested aiming 0.8 to 1.8 grams per kilogram of body weight.
Sinha also recommended staying hydrated along with strength training to build muscle. “You build up that muscle, you're going to fill up those spaces where you're losing that skin laxity,” she said.
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US journalist Norah O’Donnell recently spoke about the importance of early skin cancer detection a decade after being diagnosed with melanoma, the most dangerous form of skin cancer.
She said her experience changed her outlook towards sun protection. She also shared advice related to skin cancer from her dermatologist, Dr Elizabeth Hale.
According to CBS News, O’Donnell recalled that it was during a routine dermatology appointment when Hale noticed two concerning spots on her back.
A biopsy confirmed melanoma, but the cancer was detected early and removed before it could spread.
O’Donnell said she now seeks shade wherever she can find, wears UV-protective clothing and regularly reapplies broad-spectrum sunscreen when spending time outdoors. She also reflected on her past exposure to sunburns and tanning salons.
Melanoma develops in the cells that produce melanin, the pigment responsible for skin colour. Although it accounts for a smaller proportion of skin cancer cases, it is responsible for an alarming share of skin cancer deaths.
Hale emphasised that early detection can make a considerable difference. “Even though it only accounts for 5% of new cases of skin cancer, it’s responsible for more than 75% of skin cancer-related deaths,” she said.
She also spoke about the importance of getting suspicious spots examined rather than waiting for them to become more noticeable and serious.
“There have been major advances in melanoma treatment, but it’s still really best to get your skin checked because when melanoma is caught early it has greater than a 99% five-year survival. But once it spreads, that survival rate goes down precipitously,” Hale said.
Speaking about skin cancer risks related to tanning beds and sunburns, Hale said melanoma cases have been increasing among women in their 20s and 30s.
“It is directly related to exposure to tanning beds and to sunburns,” she said.
According to the Skin Cancer Foundation, using tanning beds before 35 could increase melanoma risk by 75%.
Hale also warned against the growing trend of deliberately seeking a tan through prolonged, unprotected sun exposure.
“There really is no such thing as … a safe, healthy tan,” she said.
A tan is not simply a cosmetic appeal. As Hale explained, it denotes “DNA damage” that may contribute to cancer later in life.
Hale recommends regular skin examinations to nab suspicious skin changes early. She advises people to discuss their individual cancer screening needs with a dermatologist, especially if they have a family history of skin cancer.
Sun protection is another essential part of prevention. Hale recommends using a broad-spectrum sunscreen with SPF 30 or higher and reapplying it every two hours when spending extended periods outdoors.
Her advice on choosing sunscreen is straightforward: “the best sunscreen is the one you’ll actually use”.
As per the Johns Hopkins Medicine, wearing sunscreen is the easiest and the best ways to protect your skin's appearance and health at any age. It recommends to use it regularly to prevent sunburn, skin cancer, and premature aging.
While everyone needs sun exposure to produce vitamin D, unprotected exposure to the sun's UV rays can cause damage to the eyes, skin, and the immune system.
To protect, apply 1 ounce of sunscreen throughout your body. To protect your face and neck, you will need about half a teaspoon of sunscreen.
Experts also believe that as long as the sunscreen is at least SPF 30 and is water-resistant, it does not matter what order you apply your skin care products. While some people find it is easiest to work with bare skin, some do it at the end.
Protective clothing and seeking shade can provide additional protection, especially during prolonged outdoor activities.
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Arthritis is sometimes treated like a normal part of getting older. Yet it can show up in many age groups. It can also limit how freely someone moves. That can affect daily independence and overall comfort.
Some people think arthritis care always means an operation, like joint replacement. In reality, the path to care is wider. What happens next depends on symptoms, which joint is affected, a person’s age, how active they are, and their general health.
Where the disease is in its early stages or is perceived to be mild, treatment will begin in a very low-key manner. This will involve physiotherapy and exercise. Where necessary, losing excess body weight can be beneficial. Minor changes in daily activities will decrease stress. Doctors will prescribe medication depending on the situation. Here, the main objective is to alleviate symptoms and maintain function. It will not be the initial step and will only be considered where appropriate.
In case arthritis is severe, pain and stiffness will persist for a long period of time. Performing simple activities becomes difficult. Even walking will become challenging. Sleep may also be affected. When this happens, it helps to check again. Doctors can use exam findings and imaging to see how much the joint has changed. They can also review whether non-surgical care is working as expected.
Good arthritis care is about choosing the right path for the right person. Timing matters too. It begins with a close look at symptoms and a clear diagnosis. Sometimes it also means getting scans when they are needed. After that, the plan should rely on what the best research shows.
Treatment should be set up with rehab in mind. The aim is to fit the person, not just the label on the chart. One person may do well with physical therapy and simple habit shifts. Another person may need a procedure, mainly when a joint is badly worn.
The main goal is easier daily comfort and better movement. Just as important, it should help someone keep their independence. It is also not only about chasing the newest option.
People should not wait until pain makes normal life hard. When they seek help early, it can be easier to see what is driving the joint pain. It can also help show how far the arthritis has gone. With that in hand, a care plan can be built with more clarity.
When care starts early and matches the person, many can stay active longer. They may also better protect joint function and keep it working well for more time.
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