A new report published in The Lancet Diabetes & Endocrinology challenges the conventional definition of obesity, and urges a shift from the reliance on Body Mass Index (BMI) to a more nuanced approach. This is supported by over 50 global medical experts. The report also recommends splitting the term "obesity" into two categories: "Clinical obesity" and "Pre-clinical obesity". This aims to improve diagnosis and treatment for over a billion people worldwide living with obesity.

Clinically Obese

This applies to individuals whose obesity has progressed to a disease state, manifesting in organ damage, heart disease, type 2 diabetes, or other health complications. These individuals could also experience symptoms like breathlessness, joint pain, or impaired daily functioning. Treatment also involves medical interventions, including weight-loss medications or surgery.

Pre-Clinic Obese

Whereas the term "pre-clinic obese" refers to those who are overweight but not yet exhibiting health issues. While they may be at risk of developing obesity-related conditions, their organ function and overall health remain intact. What they need is preventive care, which includes dietary guidance, counselling, and regular monitoring to avoid and reduce future health risks.

What does the study say?

The study, led by Professor Francesco Rubino from King's College London emphasizes that obesity is not one-size-fits-all condition. This means it should rather be treated as a spectrum as some individuals maintain normal organ function despite being classified as obese. There are others who may face severe health complications too. However, the current method of calculating obesity based on BMI often leads to misdiagnosis or inadequate care.

The report also states that BMI, while is useful for analyzing population trends, is a flawed unit of measuring individual health. Therefore, there is a need to redefine obesity, and healthcare professionals can provide more precise care by distinguishing those who need immediate medical intervention and those who require preventive strategies.

Limitations of BMI, Why It Falls Short?

BMI is used to classify individuals as underweight, healthy weight, overweight, or obese based on their height and weight. It is calculated by dividing weight in kilograms by health in meters squared. However, there are reasons while it falls short.

•Muscle vs Fat: Athletes or muscular individuals often have high BMIs despite the low body fat

•Fat Distribution: BMI does not measure fat around the waist or organs, which could be more dangerous to one's health.

•Individual Health Variation: It also overlooks the specific health conditions such as heart diseases or diabetes, or any other, while evaluating a person's category in terms of weight.

ALSO READ: Is It Time To Say Goodbye To BMI?

Scope Of Study

By redefining obesity, the study could transform the approach to diagnosis and treatment. It can focus on individual health risks rather than BMI alone. Healthcare providers can also offer tailored care. This also will ensure hat weight-loss medications like Wegovy or Mounjaro are prescribed only to those who genuinely require it.

As per Professor Louise Baur from the University of Sydney, a Children's obesity expert said that this redefinition allows both adults and children to receive more appropriate care while reducing over-diagnosis and unnecessary treatments.

Liver diseases are becoming increasingly common in India, yet many people are unaware of the difference between fatty liver and hepatitis. While both conditions affect the liver, their causes, treatment, and long-term risks are very different. Understanding these differences is important because untreated hepatitis can, in some cases, lead to liver cancer over time.

Fatty Liver And Hepatitis: What’s The Difference?

Fatty liver disease occurs when excess fat accumulates in the liver. In India, it has emerged as a major health concern due to rising rates of obesity, diabetes, sedentary lifestyles, and unhealthy dietary habits. Studies suggest that nearly one in three Indian adults may have fatty liver disease.

Also read: England Set To Become One Of The First Countries To Eliminate Hepatitis C; Here's How

Why Chronic Hepatitis Can Raise Liver Cancer Risk

One of the biggest concerns with chronic hepatitis, particularly Hepatitis B and Hepatitis C, is its association with liver cancer. The infection can silently persist for years without causing noticeable symptoms. During this period, continuous inflammation may lead to fibrosis (scarring), cirrhosis, and eventually hepatocellular carcinoma, the most common type of liver cancer.

According to the World Health Organization (WHO), chronic hepatitis B significantly increases the risk of liver cancer and remains one of the leading causes of liver cancer-related deaths worldwide.

India’s Silent Hepatitis Burden

India continues to carry a substantial burden of viral hepatitis. WHO estimates indicate that nearly 40 million Indians are living with chronic Hepatitis B infection and between six and twelve million with chronic Hepatitis C infection. Many remain undiagnosed because early disease often causes no symptoms.

Warning signs that should not be ignored include persistent fatigue, loss of appetite, abdominal discomfort, unexplained weight loss, jaundice (yellowing of the eyes and skin), dark urine, or swelling in the abdomen. However, many patients with chronic hepatitis may feel completely healthy until significant liver damage has already occurred.

Can Hepatitis-Related Liver Cancer Be Prevented?

Also read: How Chronic Hepatitis Quietly Progresses To Liver Cirrhosis: Why Early Action Can Save Your Liver

"The good news is that liver cancer arising from hepatitis is often preventable. Hepatitis B vaccination is safe and highly effective. Regular screening, timely antiviral treatment, and periodic liver monitoring can significantly reduce the risk of cirrhosis and liver cancer"- said Dr Ashwin Rajbhoj from M|O|C Cancer Care Pune. Similarly, maintaining a healthy weight, controlling diabetes, exercising regularly, and limiting alcohol intake can help prevent and reverse fatty liver disease in its early stages, he added.

The key message is simple: fatty liver and hepatitis are not the same disease. While fatty liver is primarily linked to lifestyle and metabolic health, chronic viral hepatitis can silently progress to liver cancer if neglected. Early diagnosis and timely treatment remain the best defence against serious liver complications.

By Dr Ashwin Rajbhoj, M|O|C Cancer Care, Pune

Over 57 million people worldwide live with dementia, causing 36.3 million disability-adjusted life years (DALYs) and ranking as the seventh leading cause of death. But when it comes to dementia, memory loss is often the first symptom that comes to mind.

While forgetting birthdays or losing keys are commonly considered early warning signs of dementia, this may not always be the case.

Experts say a person can remember every birthday and anniversary and still have dementia.

What Are The Early Signs Of Dementia?

“Dementia may not begin with memory loss. It can begin with smell, language, personality or navigation,” Dr Priyam Bordoloi, an internal medicine resident from Assam, said in a post on the social media platform X.

1. Loss Of Smell: When Coffee Stops Smelling Like Coffee

Dr Priyam noted that loss of smell can be an early sign, but it is often overlooked because it may be attributed to a viral illness, sinus disease, smoking, medicines or a head injury.

“Persistent, unexplained smell loss may also be an early clue to Parkinson’s disease or dementia with Lewy bodies,” he added.

2. Everyday Words Start Disappearing

It is not simply an occasional tip-of-the-tongue moment. “In primary progressive aphasia, word-finding, grammar or comprehension may worsen while recent memory stays intact,” Dr Priyam noted.

3. The Family Says, “They Are Not The Same”

Changes in personality or behaviour may sometimes appear before memory problems.

“In behavioral-variant frontotemporal dementia, apathy, impulsiveness, loss of empathy or poor judgment may come before memory loss,” Dr Priyam said.

4. A Familiar Route Suddenly Feels New

Families may notice navigation problems even when a person has no obvious memory complaints. “Families ask me, ‘He has driven there for 20 years. How did he get lost?’ When it repeats, I look beyond forgetfulness,” Dr Priyam said.

He noted that visuospatial dysfunction can appear early in dementia with Lewy bodies or posterior cortical atrophy.

One Odd Symptom Does Not Necessarily Mean Dementia

Dr Parveen Yograj, a general surgeon from Jammu, added that one unusual symptom alone means little.

"A new, persistent and progressive pattern that disrupts daily life and is noticed by loved ones is what demands attention," he said on X.

How Can Dementia Risk Be Reduced?

Dr Yograj said several lifestyle measures may help protect brain health and reduce the risk of cognitive decline.

• Exercise Regularly: Regular aerobic exercise along with strength training can boost brain blood flow and build cognitive reserve.
• Follow A Brain-Healthy Diet: A Mediterranean or MIND diet, rich in vegetables, berries, nuts, olive oil and fish, can support vascular health.
• Prioritize Good Sleep: Solid sleep helps clear toxic brain waste and supports overall brain health.
• Keep Blood Pressure, Sugar And Cholesterol In Check: Managing blood pressure, blood sugar, cholesterol and weight can help reduce the risk of vascular dementia.
• Stay Socially And Mentally Active: Stay socially connected and mentally engaged by talking with others, reading, learning new skills and playing games.
• Quit Smoking And Limit Alcohol: Avoiding smoking, limiting alcohol and treating hearing loss early can also support long-term brain health.

Organ transplantation can offer patients with end-stage organ failure a new opportunity for a longer, healthier, and more independent life. However, transplantation is not the end of treatment—it marks the beginning of a lifelong commitment to maintaining the health and function of the transplanted organ.

Successful long-term outcomes depend on close collaboration between the organ recipient, living donor, transplant team, and family. Regular medical follow-up, adherence to prescribed medications, a healthy lifestyle, and early recognition of warning signs are essential for both recipients and living donors.

Care After Organ Transplantation

1. Strict Adherence to Immunosuppressive Medications

For most solid-organ transplant recipients, lifelong immunosuppressive therapy is required to prevent the immune system from attacking the transplanted organ.

Medications such as tacrolimus, cyclosporine, mycophenolate, corticosteroids, and other immunosuppressive agents may be prescribed depending on the type of transplant and the individual patient's condition.

Recipients should:

• Take medications exactly as prescribed and at the recommended times.

• Never stop or reduce immunosuppressive medication without consulting the transplant team.

• Avoid missing doses.

• Inform their transplant physician before starting any new medication.

Even seemingly minor changes in medication can affect drug levels and may increase the risk of acute or chronic rejection.

Also read: World Organ Donation Day 2026: Too Old Or Too Sick To Donate Organs? Doctors Bust Key Myths

2. Regular Follow-Up and Laboratory Monitoring

Regular follow-up with the transplant team is an essential component of lifelong transplant care.

Depending on the transplanted organ and individual circumstances, monitoring may include:

• Kidney and liver function tests

• Complete blood counts

• Immunosuppressive drug levels

• Blood pressure and blood glucose monitoring

• Urine examination in kidney transplant recipients

• Imaging or other investigations when clinically indicated

These evaluations help detect rejection, infection, medication toxicity, or deterioration in graft function at an early stage, sometimes before symptoms become apparent.

Also read: US HHS Action Against Kentucky Organ Donation Group Raises Questions About Transplant Safety

3. Recognizing Warning Signs

Transplant recipients should promptly contact their transplant team if they develop symptoms such as:

• Unexplained or persistent fever

• Chills or significant weakness

• Reduced urine output, particularly after kidney transplantation

• Swelling or sudden weight gain

• Breathlessness or persistent cough

• Persistent pain over the transplant site

• Persistent vomiting or diarrhoea

• Unexplained changes in blood pressure or blood sugar

Because immunosuppressive medications reduce the body's immune response, infections may develop more easily and may sometimes present with subtle symptoms. Early medical assessment is therefore important.

4. Infection Prevention

Transplant recipients are more susceptible to infections, particularly during periods of intensive immunosuppression.

Important preventive measures include:

• Practising regular hand hygiene

• Avoiding close contact with individuals who have contagious infections

• Following appropriate food-safety precautions

• Drinking safe and hygienic water

• Maintaining good personal hygiene

• Keeping vaccinations up to date as advised by the transplant team

• Seeking medical advice promptly if symptoms of infection develop

Recipients should also follow the specific infection-prevention recommendations provided by their transplant centre.

5. Healthy Nutrition and Lifestyle

A balanced and nutritious diet is an important component of long-term transplant health.

Recipients should aim to:

• Maintain a healthy body weight

• Eat a balanced diet rich in vegetables, fruits, whole grains, and appropriate sources of protein

• Maintain adequate hydration unless fluid restriction has been advised

• Limit excessive salt, sugar, and processed foods

• Exercise regularly according to their medical condition and physician's advice

• Avoid smoking and tobacco products

• Avoid excessive alcohol consumption

Certain foods, supplements, and herbal preparations may interact with immunosuppressive medications. No dietary supplement, herbal preparation, or over-the-counter medication should be started without discussing it with the transplant team.

Also read: AIIMS Performs Second Dual Kidney Transplant Using Organs From 70-Year-Old Donor: How It Can Expand Donor Pool?

Post-Donation Care for Living Organ Donors

Living organ donation is a remarkable act of generosity. However, protecting the donor's long-term health remains the highest priority.

After donation, the donor should remain under appropriate medical supervision and follow the recommendations of the transplant and surgical team.

1. Recovery After Donation

The recovery period varies depending on the type of donation and the individual's overall health.

Donors should:

• Follow wound-care instructions carefully.

• Take prescribed medications as directed.

• Get adequate rest during the initial recovery period.

• Gradually resume physical activity as advised.

• Avoid strenuous exercise and heavy lifting until medically cleared.

• Return to work and normal activities progressively.

The recovery process should be individualized rather than based solely on a fixed timeline.

2. Long-Term Health After Kidney Donation

Most carefully selected kidney donors can lead healthy, active lives with a single functioning kidney.

Long-term health recommendations include:

• Maintaining a healthy body weight

• Exercising regularly

• Eating a balanced diet

• Staying adequately hydrated

• Avoiding tobacco

• Avoiding unnecessary use of potentially kidney-toxic medications, particularly certain painkillers such as NSAIDs

• Monitoring blood pressure

• Periodically checking kidney function and urine as recommended

Living donation should never mean that donors stop looking after their own health. The donor's well-being remains a lifelong priority.

Any new or persistent symptoms should be reported to a healthcare professional.

Also read: India Records 20,138 Organ Transplants In 2025; Deceased Donor Transplants Reach 3,526

3. Emotional and Psychological Well-Being

Transplantation and organ donation can have a significant emotional impact on both recipients and donors.

Recipients may experience anxiety related to rejection, medication, financial concerns, or the uncertainty associated with transplantation. Living donors may also experience emotional changes during the recovery period.

Maintaining open communication with family members and the transplant team can be extremely helpful. If persistent anxiety, depression, sleep disturbances, or emotional distress develops, professional psychological or psychiatric support should be sought.

4. The Importance of Lifelong Follow-Up

The success of organ transplantation depends not only on the surgical procedure but also on long-term post-transplant care.

For recipients, medication adherence, regular monitoring, infection prevention, and a healthy lifestyle are essential to preserving graft function.

For living donors, appropriate postoperative recovery, long-term health monitoring, and healthy lifestyle practices help ensure that they continue to live healthy and fulfilling lives after donation.

The transplant may be a single surgical event—but maintaining the gift of life is a lifelong journey.

With appropriate medical supervision, adherence to treatment, healthy lifestyle choices, and timely attention to warning signs, organ recipients can protect the health of their transplanted organ, while living donors can continue to enjoy a healthy and active life after their selfless contribution.

By Dr. Pragnesh Desai, Senior Director & HOD – Urology, Renal Transplant, Robotics & Uro-Oncology, Yatharth Super Speciality Hospital, Noida Extension