A new report published in The Lancet Diabetes & Endocrinology challenges the conventional definition of obesity, and urges a shift from the reliance on Body Mass Index (BMI) to a more nuanced approach. This is supported by over 50 global medical experts. The report also recommends splitting the term "obesity" into two categories: "Clinical obesity" and "Pre-clinical obesity". This aims to improve diagnosis and treatment for over a billion people worldwide living with obesity.
This applies to individuals whose obesity has progressed to a disease state, manifesting in organ damage, heart disease, type 2 diabetes, or other health complications. These individuals could also experience symptoms like breathlessness, joint pain, or impaired daily functioning. Treatment also involves medical interventions, including weight-loss medications or surgery.
Whereas the term "pre-clinic obese" refers to those who are overweight but not yet exhibiting health issues. While they may be at risk of developing obesity-related conditions, their organ function and overall health remain intact. What they need is preventive care, which includes dietary guidance, counselling, and regular monitoring to avoid and reduce future health risks.
The study, led by Professor Francesco Rubino from King's College London emphasizes that obesity is not one-size-fits-all condition. This means it should rather be treated as a spectrum as some individuals maintain normal organ function despite being classified as obese. There are others who may face severe health complications too. However, the current method of calculating obesity based on BMI often leads to misdiagnosis or inadequate care.
The report also states that BMI, while is useful for analyzing population trends, is a flawed unit of measuring individual health. Therefore, there is a need to redefine obesity, and healthcare professionals can provide more precise care by distinguishing those who need immediate medical intervention and those who require preventive strategies.
BMI is used to classify individuals as underweight, healthy weight, overweight, or obese based on their height and weight. It is calculated by dividing weight in kilograms by health in meters squared. However, there are reasons while it falls short.
•Muscle vs Fat: Athletes or muscular individuals often have high BMIs despite the low body fat
•Fat Distribution: BMI does not measure fat around the waist or organs, which could be more dangerous to one's health.
•Individual Health Variation: It also overlooks the specific health conditions such as heart diseases or diabetes, or any other, while evaluating a person's category in terms of weight.
ALSO READ: Is It Time To Say Goodbye To BMI?
By redefining obesity, the study could transform the approach to diagnosis and treatment. It can focus on individual health risks rather than BMI alone. Healthcare providers can also offer tailored care. This also will ensure hat weight-loss medications like Wegovy or Mounjaro are prescribed only to those who genuinely require it.
As per Professor Louise Baur from the University of Sydney, a Children's obesity expert said that this redefinition allows both adults and children to receive more appropriate care while reducing over-diagnosis and unnecessary treatments.
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A large population-based study from Linköping University in Sweden has found no evidence that COVID-19 vaccination caused a decline in childbirth during the pandemic, countering persistent rumors that mRNA vaccines affect fertility. The findings have been published in the peer-reviewed journal Communications Medicine.
The study was conducted amid widespread misinformation, particularly on social media, suggesting that COVID-19 vaccines reduce the chances of becoming pregnant. These claims gained traction as several countries, including Sweden, recorded a drop in birth rates during the later stages of the pandemic, prompting questions about a possible link to vaccination.
“Our conclusion is that it’s highly unlikely that the mRNA vaccine against COVID-19 was behind the decrease in childbirth during the pandemic,” said Toomas Timpka, professor of social medicine at Linköping University and one of the study’s authors.
Since the early months of the pandemic, unverified claims about vaccines and fertility have circulated widely online. When official data later showed fewer babies being born in some regions, researchers decided to examine whether vaccination could plausibly explain the trend or whether other social and demographic factors were at play.
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To address the issue, the research team carried out an extensive analysis using real-world healthcare data rather than surveys or self-reported outcomes.
The study analyzed health records of all women aged 18 to 45 years living in Region Jönköping County, a region with a total population of around 369,000 people. This amounted to nearly 60,000 women included in the analysis.
Between 2021 and 2024, about 75 per cent of these women received at least one dose of a COVID-19 vaccine. Researchers examined data on childbirths, registered miscarriages, vaccination status and deaths using official healthcare records, allowing for a comprehensive comparison between vaccinated and unvaccinated groups.
Importantly, the researchers adjusted their analysis for age, recognizing that age is one of the most significant factors influencing fertility and pregnancy outcomes.
When childbirth rates were compared between vaccinated and unvaccinated women, the researchers found no statistically significant difference. The same held true for miscarriage rates among women who became pregnant during the study period.
“We see no difference in childbirth rates between those who have taken the vaccine and those who haven’t,” said Timpka. “We’ve also looked at all registered miscarriages among those who became pregnant, and we see no difference between the groups there either.”
These findings align with several earlier international studies that have similarly found no association between COVID-19 vaccination and reduced fertility.
According to the researchers, the decline in childbirth observed during the pandemic is more plausibly explained by broader demographic and social trends.
People currently in their 30s, the age group most likely to have children, were born in the second half of the 1990s. That period was marked by economic challenges and lower birth rates in Sweden, meaning today’s pool of potential parents is smaller than in previous generations.
In addition, pandemic-related factors such as health concerns, economic uncertainty, delayed family planning and lifestyle changes during lockdowns may have contributed to fewer pregnancies.
One of the study’s key strengths is its large, representative sample drawn from an entire region rather than a selected group. By using verified healthcare records and accounting for age-related effects, the researchers aimed to minimize bias and improve reliability.
The study received financial support from several sources, including the Swedish Research Council.
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In 2022, there were almost 20 million new cases of cancer and 9.7 million cancer-related deaths worldwide, noted the National Cancer Institute (US). By 2050, it is predicted that the number of new cancer cases will rise to 33 million per year, with deaths rising to 18.2 million. While there are many reasons for cancer, a new comprehensive study by the World Health Organization (WHO) revealed that there are two major habits that are the leading cause of cancer.
As per WHO, more than 38% of cancer cases worldwide are linked to modifiable risk factors. The study is published in the journal Nature Medicine and it suggests that millions of diagnoses each year could be avoided through lifestyle changes, medical interventions, and environmental improvements.
As per the Association of Tobacco Use and Cancer Incidence, in India, the risk of any cancer with smoke and smokeless tobacco is 2.71 and 2.68, respectively. The study noted that risk of cancer due to tobacco use is consistent especially in India. Site-specific analysis showed higher risks of respiratory system cancers of 4.97 and head and neck cancers of 3.95.
As per several studies, including Cancer Research UK and National Institutes of Health (NIH), tobacco causes approximately 2.5 million cancer deaths globally, every year. This means, it accounts for 1 in every 4 global cancer death. It is also linked to 16 to 20 different types of cancer.
The WHO ranked it as the top reason for cancer, which is responsible for 15% of all global cancer cases. The impact is more in men, leading to 23% more new diagnoses.
The WHO study ranks it as the second most significant lifestyle factor that accounts for 700,000 new cases annually, leading to 3.2% of global cancer cases.
As per the National Cancer Institute (US), alcohol consumption is a significant, preventable cause of cancer, responsible for an estimated 741,300 to 750,000 new cancer cases worldwide in 2020. It is linked to cancers of the mouth, throat, esophagus, liver, colon, and breast. Even light-to-moderate drinking contributes, with about 185,100 cases annually tied to consuming two or fewer drinks per day.
Air pollution is a major cause of lung cancer, particularly in heavily polluted regions. In East Asia, for instance, around 15 per cent of lung cancer cases in women are linked to poor air quality. Experts say this underlines the urgent need for cleaner energy and stricter pollution controls.
Infections are another significant contributor, accounting for about 10 per cent of new cancer cases globally. High-risk strains of the human papillomavirus are the leading cause of cervical cancer, while stomach cancer is often linked to infections associated with unsafe water and poor sanitation.
Other important risk factors include high body mass index, lack of physical activity and excessive exposure to ultraviolet radiation, all of which continue to drive cancer rates across different populations.
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The number of autistic women is same as the number of autistic men, but women know to hide it well, says research. A study published in the BMJ, found that while the rates of diagnosis for autistic is found among young boys and girls, rates are almost identical by the time they reach adulthood. However, these new findings have also shown that women are more likely to "mask" signs of autism in order to fit in. This is why their diagnosis is done far later.
This is the first major study to find such high levels of condition among women. Previously, diagnoses rates were four times higher among boys and men than females.
Specialists say the findings highlight the urgent need to move away from outdated stereotypes that still influence how autism is recognized and diagnosed.
The international study, led by researchers at the Karolinska Institutet in Sweden, examined autism diagnosis rates among people born in Sweden between 1985 and 2000. More than 2.7 million individuals were followed for up to 37 years, making it one of the most comprehensive studies of its kind.
By 2022, around 2.8 per cent of the population studied had been diagnosed with autism spectrum disorder. The data revealed a clear pattern. In early childhood, boys were far more likely than girls to receive an autism diagnosis. However, this gap steadily narrowed during adolescence.
By the time participants reached their late teens and early 20s, diagnosis rates among men and women were broadly similar. Researchers noted that the male to female ratio of autism diagnoses decreased over time to the point that it may no longer be distinguishable in adulthood.
Dr Caroline Fyfe, lead author of the study from the University of Edinburgh, said autism has long been viewed as a condition that mainly affects males. While that pattern was still visible in children under 10, the picture changed rapidly during adolescence.
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She explained that diagnoses among girls rose sharply in the teenage years, creating what researchers described as a female catch-up effect. By the age of 20, autism rates were almost equal between men and women. According to Dr Fyfe, this suggests late or missed diagnoses in females rather than a true biological difference between sexes.
Experts say one major reason for delayed diagnosis is masking. Girls and women are often more likely to imitate social behavior, maintain eye contact and suppress traits traditionally associated with autism. While this can help them fit in socially, it can also make their difficulties harder to identify in clinical settings.
Dr Judith Brown from the National Autistic Society said gender should never be a barrier to diagnosis or support. She noted that autistic women who are misdiagnosed often develop additional mental health challenges due to years without appropriate understanding or help.
She added that the exhaustion of constant masking can contribute to anxiety and depression, reinforcing the importance of recognizing autism earlier in girls.
Dr Steven Kapp, senior lecturer in psychology at the University of Portsmouth, said research has consistently shown that clinical biases play a role in under-recognizing autism in women and girls. He explained that subtler behaviors and social adaptation often lead clinicians to overlook autism in females.
A linked editorial written by a patient and advocate echoed these concerns, warning that autistic women are frequently labelled with mood or personality disorders while waiting for a correct diagnosis. As a result, many are forced to self-advocate simply to be recognized as autistic.
Experts say the findings should prompt changes in diagnostic approaches, ensuring that autistic girls and women are no longer left unseen.
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