A new report published in The Lancet Diabetes & Endocrinology challenges the conventional definition of obesity, and urges a shift from the reliance on Body Mass Index (BMI) to a more nuanced approach. This is supported by over 50 global medical experts. The report also recommends splitting the term "obesity" into two categories: "Clinical obesity" and "Pre-clinical obesity". This aims to improve diagnosis and treatment for over a billion people worldwide living with obesity.
This applies to individuals whose obesity has progressed to a disease state, manifesting in organ damage, heart disease, type 2 diabetes, or other health complications. These individuals could also experience symptoms like breathlessness, joint pain, or impaired daily functioning. Treatment also involves medical interventions, including weight-loss medications or surgery.
Whereas the term "pre-clinic obese" refers to those who are overweight but not yet exhibiting health issues. While they may be at risk of developing obesity-related conditions, their organ function and overall health remain intact. What they need is preventive care, which includes dietary guidance, counselling, and regular monitoring to avoid and reduce future health risks.
The study, led by Professor Francesco Rubino from King's College London emphasizes that obesity is not one-size-fits-all condition. This means it should rather be treated as a spectrum as some individuals maintain normal organ function despite being classified as obese. There are others who may face severe health complications too. However, the current method of calculating obesity based on BMI often leads to misdiagnosis or inadequate care.
The report also states that BMI, while is useful for analyzing population trends, is a flawed unit of measuring individual health. Therefore, there is a need to redefine obesity, and healthcare professionals can provide more precise care by distinguishing those who need immediate medical intervention and those who require preventive strategies.
BMI is used to classify individuals as underweight, healthy weight, overweight, or obese based on their height and weight. It is calculated by dividing weight in kilograms by health in meters squared. However, there are reasons while it falls short.
•Muscle vs Fat: Athletes or muscular individuals often have high BMIs despite the low body fat
•Fat Distribution: BMI does not measure fat around the waist or organs, which could be more dangerous to one's health.
•Individual Health Variation: It also overlooks the specific health conditions such as heart diseases or diabetes, or any other, while evaluating a person's category in terms of weight.
ALSO READ: Is It Time To Say Goodbye To BMI?
By redefining obesity, the study could transform the approach to diagnosis and treatment. It can focus on individual health risks rather than BMI alone. Healthcare providers can also offer tailored care. This also will ensure hat weight-loss medications like Wegovy or Mounjaro are prescribed only to those who genuinely require it.
As per Professor Louise Baur from the University of Sydney, a Children's obesity expert said that this redefinition allows both adults and children to receive more appropriate care while reducing over-diagnosis and unnecessary treatments.
Uncontrolled eczema can also make sleep disorders worse. (Photo credit: AI generated)
Every year on May 5, World Asthma Day is observed, an event that aims at spreading awareness about the respiratory disorders. While asthma is becoming a common occurrence in India, citing excessive pollution and unhealthy lifestyle choices. But in a shocking revelation on the occasion, Dr. Gitika Sanodia, Consultant Dermatologist at Dr L H Hiranandani Hospital, Powai, revealed that leaving eczema untreated could lead to chronic asthma. Talking about it, Dr Sanodia answered some common FAQs about eczema and asthma.
Yes, especially for those suffering from early childhood onset of moderate/severe atopic dermatitis. Eczema is not always limited to being solely a skin condition. In many cases, patients who suffer from eczema actually have one part of the atopic triad, which means the patient's skin barrier is dysfunctional, allowing for allergens to enter and sensitize the immune system. With time, the same tendency can impact other organs, causing allergic rhinitis or asthma. However, it must be noted that not all children with eczema develop asthma.
Because of symptoms including itching, dryness, redness, scaling, and oozing from the skin. The families take care to control the acute phase of eczema while ignoring the patient's predisposition to allergies. Furthermore, atopic dermatitis is an inflammatory skin condition that is accompanied by impaired skin barrier function, immune dysfunction, and environmental factors. Moreover, according to DermNet, atopy is a term used for conditions where eczema, rhinitis, and asthma happen together.
Parents should worry if their children with eczema exhibit recurrent coughs, wheezing, noisy breathing, difficulties breathing during playtime, nighttime coughing, chest tightness, frequent sneezing, nasal blockage, allergic rhinitis, or exacerbation of symptoms following exposure to dust, animal dander, pollens, airborne particles, or fluctuating environmental conditions.
Successful treatment of eczema can help minimize the chances of allergens penetrating the skin barrier and allergic inflammation. Nonetheless, it would not be accurate to predict with certainty that eczema therapy will effectively prevent the onset of asthma. Literature recommends the prompt restoration of the skin barrier function, regular application of moisturizing agents, avoiding triggers such as fragrances and harsh soaps, managing flare-ups with prescription corticosteroid creams, controlling infections, and referring patients with severe eczema cases.
Yes. This condition is becoming more common, especially among children. If not controlled effectively, eczema will result in poor sleeping habits, difficulties with academic performance, reduced quality of life, greater susceptibility to infections, and potentially even links to other allergies. People lack sufficient information regarding the condition because they normally medicate themselves by applying whatever ointment or steroid to their skin.
Credit: AI generated image
Asthma is often thought of as an "outdoor" problem, with triggers such as smog, pollen, or car exhaust. But for many, the real danger may be sitting right there on the sofa or hiding under the sink.
The chronic condition affects over 260 million people. It is also responsible for over 450,000 deaths each year worldwide.
If you're doing everything right with your inhaler but still feel that tightness in your chest, it’s time to look at silent indoor triggers.
1. The Bedding "Dynasty"
“It’s a bit unsettling, but your mattress is likely home to millions of microscopic dust mites. They love the warmth and humidity of a bed. You won't see them, but you’ll feel them,” Dr. Sandeep Nayar, Principal Director & HOD - Chest & Respiratory Diseases, BLK Max Super Speciality Hospital, told HealthandMe.
The Fix: Don’t just wash your sheets; use hot water (60°C). If you haven't encased your pillows in allergen-proof covers yet, make that your priority this weekend.
2. Moisture is the Enemy
Dr Nayar said mold isn't always a giant green patch. It hides in the "sweat" behind your wallpaper or the damp corners of a bathroom that doesn't vent well. If a room smells even slightly musty, mold spores are likely in the air.
The Tip: Keep your home's humidity below 50 per cent. A simple dehumidifier can sometimes do more for your lungs than an extra dose of medicine.
3. It’s Not Just the Fur
Many people think "hypoallergenic" pets are the cure. It’s actually a protein in pet saliva and skin flakes (dander) that causes the flare-up.
The Reality: Even if you keep the dog off the bed, dander travels on your clothes. HEPA air purifiers are a must-have if you share your home with a furry friend.
4. The "Clean" Smell Myth
That "fresh lemon" scent or your favorite scented candle? Those are Volatile Organic Compounds (VOCs). To a sensitive lung, those chemicals are irritants, not cleaners.
The Switch: Move toward fragrance-free products. If a cleaning spray makes you cough, your body is telling you everything you need to know.
5. Urban Uninvited Guests
In cities, cockroach droppings are a massive, often ignored asthma trigger. Their proteins mix with household dust and get kicked up every time you walk across the floor.
The Strategy: Seal the cracks in your walls and keep the kitchen bone-dry.
Other asthma triggers include dust mites, pet dander, indoor smoke, and strong cleaning agents that can worsen symptoms over time
Dr. Manisha Mendiratta, Director & Head - Pulmonology, Sarvodaya Hospital, Faridabad, told HealthandMe that the key is prevention through simple, consistent habits. To make a meaningful difference, the expert urged people to
“Most importantly, patients should identify their personal triggers and act early, because managing their indoor environment is just as critical as managing their medication,” added Dr. Mendiratta.
Credit: Canva
Cancer is a complex disease, and its diagnosis often involves multiple tests, procedures, and high costs. Patients frequently undergo several blood draws and investigations before a clear result is reached.
Now, a revolutionary new low-cost test has shown promise in detecting multiple cancers using just a single blood sample.
Beyond cancer detection, the test may also help identify various liver conditions and organ abnormalities by analyzing DNA fragments circulating in the bloodstream.
The test, developed by scientists at the University of California, Los Angeles, is known as MethylScan. The novel test works by analyzing cell-free DNA, tiny fragments of genetic material released into the blood when cells die.
In early tests, MethylScan detected about 63 per cent of cancers across all stages and roughly 55 per cent of early-stage cancers.
The test, described in the journal Proceedings of the National Academy of Sciences, could offer a powerful and more affordable approach to early disease detection and comprehensive health monitoring.
“Early detection is crucial,” said Dr. Jasmine Zhou, Professor of Pathology at UCLA Health.
“Survival rates are far higher when cancers are caught before they spread. If you detect cancer at stage one, outcomes are dramatically better than at stage four,” Dr Zhou added.
MethylScan studies DNA methylation—chemical tags on DNA that reflect tissue health and can change when disease develops.
Since most circulating DNA comes from healthy cells, advanced machine learning is used to identify subtle disease signals.
In the study, MethylScan analyzed blood samples from 1,061 people, including patients with liver, lung, ovarian, and stomach cancers.
For multi-cancer detection, the test achieved a high level of overall accuracy. At a specificity of 98 per cent, meaning few false positives, it detected about 63 per cent of cancers across all stages and roughly 55 per cent of early-stage cancers.
The test also performed well in liver cancer surveillance among high-risk individuals, including those with liver cirrhosis or HBV. It detected nearly 80 per cent of cases at a specificity of just over 90 per cent, meaning a less than 10 per cent false positive rate.
The blood test could also distinguish between different types of liver disease, including viral hepatitis and metabolic-associated liver disease. It correctly classified about 85 per cent of patients, suggesting blood-based DNA testing could reduce the need for invasive liver biopsies.
In addition, the researchers noted that MethylScan can work like a health radar for the body. By reading DNA signals in the blood, it can tell when specific organs, such as the liver or lungs, are under stress or damaged, even without knowing the disease in advance.
“This study demonstrates that blood-based methylation profiling can deliver clinically meaningful information across multiple diseases,” said Zhou. “It’s an exciting advancement that brings us closer to realizing the dream of a single assay for universal disease detection.”
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