A new report published in The Lancet Diabetes & Endocrinology challenges the conventional definition of obesity, and urges a shift from the reliance on Body Mass Index (BMI) to a more nuanced approach. This is supported by over 50 global medical experts. The report also recommends splitting the term "obesity" into two categories: "Clinical obesity" and "Pre-clinical obesity". This aims to improve diagnosis and treatment for over a billion people worldwide living with obesity.
This applies to individuals whose obesity has progressed to a disease state, manifesting in organ damage, heart disease, type 2 diabetes, or other health complications. These individuals could also experience symptoms like breathlessness, joint pain, or impaired daily functioning. Treatment also involves medical interventions, including weight-loss medications or surgery.
Whereas the term "pre-clinic obese" refers to those who are overweight but not yet exhibiting health issues. While they may be at risk of developing obesity-related conditions, their organ function and overall health remain intact. What they need is preventive care, which includes dietary guidance, counselling, and regular monitoring to avoid and reduce future health risks.
The study, led by Professor Francesco Rubino from King's College London emphasizes that obesity is not one-size-fits-all condition. This means it should rather be treated as a spectrum as some individuals maintain normal organ function despite being classified as obese. There are others who may face severe health complications too. However, the current method of calculating obesity based on BMI often leads to misdiagnosis or inadequate care.
The report also states that BMI, while is useful for analyzing population trends, is a flawed unit of measuring individual health. Therefore, there is a need to redefine obesity, and healthcare professionals can provide more precise care by distinguishing those who need immediate medical intervention and those who require preventive strategies.
BMI is used to classify individuals as underweight, healthy weight, overweight, or obese based on their height and weight. It is calculated by dividing weight in kilograms by health in meters squared. However, there are reasons while it falls short.
•Muscle vs Fat: Athletes or muscular individuals often have high BMIs despite the low body fat
•Fat Distribution: BMI does not measure fat around the waist or organs, which could be more dangerous to one's health.
•Individual Health Variation: It also overlooks the specific health conditions such as heart diseases or diabetes, or any other, while evaluating a person's category in terms of weight.
ALSO READ: Is It Time To Say Goodbye To BMI?
By redefining obesity, the study could transform the approach to diagnosis and treatment. It can focus on individual health risks rather than BMI alone. Healthcare providers can also offer tailored care. This also will ensure hat weight-loss medications like Wegovy or Mounjaro are prescribed only to those who genuinely require it.
As per Professor Louise Baur from the University of Sydney, a Children's obesity expert said that this redefinition allows both adults and children to receive more appropriate care while reducing over-diagnosis and unnecessary treatments.
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A team of researchers in the US has developed a nanoparticle-based technique that could make laser surgeries for kidney stones faster, safer, and potentially reduce the chances of recurrence.
Engineers from the University of Chicago and doctors from Duke University added dark nanoparticles to a common saline solution used in kidney stone laser surgeries. Their method also promised less recurrence of disease.
The research focused on laser lithotripsy, a widely used surgical method in which lasers are used to break kidney or urinary tract stones into tiny fragments that can then be removed by suctioning or pass naturally.
Traditionally, surgeons use a small video-guided laser to fragment the stones. However, achieving effective fragmentation often requires higher laser power, which generates additional heat and causes damage to the surrounding tissues.
Thus the new method “is a way to better utilize the laser energy that is already being employed,” said Po-Chun Hsu, assistant professor at the University of Chicago Pritzker School of Molecular Engineering (UChicago PME).
Hsu noted that their nanoparticle-based “nanofluid” also has the potential to enhance the performance of lasers without increasing power levels. This will effectively fragment the stones and remove the dust particles.
The study, published in the journal Advanced Science, describes an innovative saline solution that enhances the performance of existing laser systems without requiring modifications to the equipment.
By adding dark nanoparticles that absorb laser wavelengths, the solution ensures that more of the laser energy is directed at the kidney stone rather than being reflected or dispersed.
“This improves the amount of laser energy that is transmitted to and absorbed by the stones,” said corresponding author Pei Zhong, a professor of engineering at Duke University.
“Nanofluid introduces a new dimension that can influence this complex physical process, independent of the stone composition or the laser being used,” Zhong said.
Laboratory tests using artificial kidney stones showed that the nanofluid increased stone ablation efficiency by between 38 and 727 percent in spot treatments and by 26 to 75 percent in scanning treatments.
The researchers also tested the nanoparticle solution on living cells for up to 24 hours and found it to be non-toxic and safe.
In clinical settings, however, exposure would be much shorter. Laser lithotripsy is typically an outpatient procedure lasting about 30 minutes. The researchers believe that improved laser absorption could reduce the procedure time to around 10 minutes.
“If surgeries take too long, waste heat from the laser can accumulate and cause more harm than the stone removal itself,” Hsu said.
Kidney stones are hard mineral or acid salt deposits formed in the kidneys. It occurs due to concentrated urine, and causes intense, radiating back/side pain, nausea, and blood in urine.
Common causes include
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Former youth player of England, Amy Carr dies at the age of 35. England women's football team too paid tribute on her death. Carr was a former goalkeeper who played for England Under-17s and Under-19s. She was diagnosed with a brain tumor for a second time.
She was diagnosed in 2015 and raised more than £2,000 for charity by running the Dublin Marathon in 2024.
"We are heartbroken to hear that former England youth player Amy Carr has passed away aged 35," read a statement on the Lionesses' X account. "Amy, who was diagnosed with a second brain tumour in 2024, devoted her time to raising money for vital brain tumour research that could help others. She remains an inspiration to all."
Carr also played for Arsenal, Chelsea and Reading before she gained a football scholarship in the USA. Chelsea added on X: "We are saddened to learn of the passing of former Chelsea goalkeeper, Amy Carr. Our condolences are with Amy's friends and family at this time."
Before diving into the concept of a brain tumor, it is important to first understand what a tumor is. A tumor refers to an abnormal lump or mass that forms due to the uncontrolled growth of cells in the body.
A benign tumor consists of normal cells that have grown excessively to form a lump. This overgrowth may result from something going wrong in the body, but the cells themselves are not cancerous. On the other hand, a malignant tumor is made up of abnormal cells that grow uncontrollably. These are cancerous cells, and their aggressive nature can lead to serious health issues.
A brain tumor is a condition in which abnormal cells develop within any part of the brain. Similar to tumors elsewhere in the body, brain tumors can also be benign (non-cancerous) or malignant (cancerous). The presence of a tumor in the brain can interfere with normal brain function, depending on its size, type, and location.
Our bodies possess a natural healing mechanism that is crucial for survival. This repair system is activated whenever there is damage from injury, radiation from the sun, or harmful chemicals in the environment. However, this process can occasionally go wrong. When it does, small clusters of cancerous cells may begin to form. In most cases, the immune system successfully detects and destroys these abnormal cells before they grow. But in rare instances, these cancerous cells evade immune detection and continue to grow, leading to the formation of tumors or cancers.
Such abnormal growths can occur anywhere in the body. When these growths are located in the brain or spinal cord, they are referred to as Central Nervous System (CNS) tumors.
Credits: Canva
India is home to 25 per cent of the world's annual count of cervical cancer fatalities. According to the World Health Organization GLOBOCAN report of 2022, India reports over 120,000 new cases with nearly 80,000 fatalities. This is the highest death-toll worldwide from cervical cancer each year.
In India, a new case is diagnosed every four minutes, and another woman dies approximately every seven minutes. Persistent infection with high-risk HPV strains, especially types 16 and 18, is the leading cause of cervical cancer. Meanwhile, studies show that even a single dose of the HPV vaccine can provide long-lasting, potentially lifelong protection.
To combat this, India launched a nationwide campaign to vaccinate young girl against the human papillomavirus (HPV). This is also the second most common cancer among women in the country. India kicked off the nationwide campaign on 28 February. Prime Minister Narendra Modi at Ajmer city in the western state of Rajasthan inaugurated this campaign. Vaccines were made available free-of-cost at government facilities to approximately 11.5 million girls aged 14 years across the country.
Currently, approximately one in every 50 girls born in India is expected to develop cervical cancer during her lifetime, and widespread vaccination is likely to reduce this risk significantly," said Partha Basu, Head, Early Detection, Prevention & Infections Branch at the International Agency for Research on Cancer.
Cervical cancer develops in a women's cervix (uterus opening) due to abnormal cell growth, primarily caused by persistent HPV infection, a common infection that's passed through sexual contact.
When exposed to HPV, the body's immune system typically prevents the virus from causing damage however, in a small percentage of people, the virus can survive for years and pave the way for some cervical cells to become cancerous.
Treatment involves surgery, radiation, and chemotherapy, with early detection significantly improving outcomes, though it remains a major cancer in low-income countries Cervical cancer can also be prevented through vaccination and regular screening (Pap/HPV tests).
Cervical cancer has no symptoms in the early days and therefore, is hard to detect until it has spread. However, the early-stage symptoms include:
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