A new report published in The Lancet Diabetes & Endocrinology challenges the conventional definition of obesity, and urges a shift from the reliance on Body Mass Index (BMI) to a more nuanced approach. This is supported by over 50 global medical experts. The report also recommends splitting the term "obesity" into two categories: "Clinical obesity" and "Pre-clinical obesity". This aims to improve diagnosis and treatment for over a billion people worldwide living with obesity.

Clinically Obese

This applies to individuals whose obesity has progressed to a disease state, manifesting in organ damage, heart disease, type 2 diabetes, or other health complications. These individuals could also experience symptoms like breathlessness, joint pain, or impaired daily functioning. Treatment also involves medical interventions, including weight-loss medications or surgery.

Pre-Clinic Obese

Whereas the term "pre-clinic obese" refers to those who are overweight but not yet exhibiting health issues. While they may be at risk of developing obesity-related conditions, their organ function and overall health remain intact. What they need is preventive care, which includes dietary guidance, counselling, and regular monitoring to avoid and reduce future health risks.

What does the study say?

The study, led by Professor Francesco Rubino from King's College London emphasizes that obesity is not one-size-fits-all condition. This means it should rather be treated as a spectrum as some individuals maintain normal organ function despite being classified as obese. There are others who may face severe health complications too. However, the current method of calculating obesity based on BMI often leads to misdiagnosis or inadequate care.

The report also states that BMI, while is useful for analyzing population trends, is a flawed unit of measuring individual health. Therefore, there is a need to redefine obesity, and healthcare professionals can provide more precise care by distinguishing those who need immediate medical intervention and those who require preventive strategies.

Limitations of BMI, Why It Falls Short?

BMI is used to classify individuals as underweight, healthy weight, overweight, or obese based on their height and weight. It is calculated by dividing weight in kilograms by health in meters squared. However, there are reasons while it falls short.

•Muscle vs Fat: Athletes or muscular individuals often have high BMIs despite the low body fat

•Fat Distribution: BMI does not measure fat around the waist or organs, which could be more dangerous to one's health.

•Individual Health Variation: It also overlooks the specific health conditions such as heart diseases or diabetes, or any other, while evaluating a person's category in terms of weight.

ALSO READ: Is It Time To Say Goodbye To BMI?

Scope Of Study

By redefining obesity, the study could transform the approach to diagnosis and treatment. It can focus on individual health risks rather than BMI alone. Healthcare providers can also offer tailored care. This also will ensure hat weight-loss medications like Wegovy or Mounjaro are prescribed only to those who genuinely require it.

As per Professor Louise Baur from the University of Sydney, a Children's obesity expert said that this redefinition allows both adults and children to receive more appropriate care while reducing over-diagnosis and unnecessary treatments.

The brain is a crucial component of the human body. It is an integral part of the whole system, but when the body ages, the brain does too. The brain is the organ that plays a big role in the aging process. The brain protein is an important component of the body, and can positively impact inflammation, memory decline, and other age-related changes.

A recent study conducted by PLOS Biology claims that the brain protein Menin loss can be crucial to inflammation, memory decline, and other age-related changes. The researchers in the study used mice as test subjects and tried to restore the very protein in them, which worked marvelously; aging conditions were completely reversed.

The study found that aging can be highly influenced by the hypothalamus, a strong brain region that regulates metabolism, hormones, body temperature, sleep, and stress responses. According to the researchers, the hypothalamus is a central command centre for aging.

The research was done by Lige Leng and colleagues at Xiamen University in China and mainly focused on the Menin. They intended to see what the impact would be if someone lost this very important protective protein. The study on mice shows that when Menin levels drop in the hypothalamus, it causes faster aging.

The study specifically used young mice and reduced menin levels; as a result, they faced brain inflammation, thinning skin, lower bone mass, impaired balance, memory problems, and a shorter lifespan. Thus, the conclusion of the research was that menin is likely to act as an anti-aging component in the body.

How Much Protein Do You Really Need?

Your protein needs aren’t one-size-fits-all. They depend on several factors: your weight, age, physical activity, body composition goals, and overall health status.

The Recommended Dietary Allowance (RDA) for the average adult is 0.36 grams per pound (0.8 grams per kilogram) of body weight. This amount is to meet basic nutritional needs in most sedentary adults.

However, experts suggest that physically active people often need more, anywhere from 0.54 to 0.9 grams per pound (1.2–2 grams per kilogram) per day. Athletes may even require higher amounts to support muscle repair and performance.

Certain groups, such as pregnant or breastfeeding individuals, older adults, and people recovering from illness or injury, also have increased protein needs. For example, during pregnancy, the recommendation rises to about 0.5 grams per pound (1.1 grams per kilogram).

According to the World Health Organization (WHO), tobacco use kills over 8 million people globally each year, including non-smokers exposed to second-hand smoke.

India continues to face a massive burden of tobacco addiction. Cigarettes, bidis, gutka, pan masala and khaini continue to affect millions, including young adults. This year’s WHO theme- “Unmasking the Appeal: Countering Nicotine and Tobacco Addiction” focuses on how flavoured products, attractive packaging and social media marketing are making nicotine products appealing to the younger generation.

Tobacco damages nearly every organ in the body. It is strongly linked to cancers of the mouth, throat, voice box, lungs, food pipe and bladder. In India, oral cancer remains one of the commonest cancers, largely driven by smokeless tobacco use. Tobacco also increases the risk of heart attacks, strokes, chronic lung disease, infertility and poor immunity.

Many people mistakenly believe that e-cigarettes and vaping are “safe alternatives.” However, e-cigarettes still contain addictive nicotine and harmful chemicals that can damage the lungs and cardiovascular system. They may also act as a gateway to conventional tobacco use among teenagers and young adults. Recognising these risks, India banned the production, sale and advertisement of e-cigarettes under the Prohibition of Electronic Cigarettes Act, 2019.

The encouraging fact is that quitting works at any age. Within weeks of stopping tobacco, blood pressure and lung function begin to improve, while long-term risks of cancer and heart disease reduce significantly.

Simple Steps To Quit Tobacco

* Fix a quit date and inform family and friends.

* Identify triggers such as stress, tea, alcohol or social gatherings.

* Avoid keeping tobacco products nearby.

* Stay physically active and hydrated.

* Seek professional counselling if cravings are severe.

* Nicotine replacement therapy or prescribed medications may help selected individuals.

* Remember that relapses can happen and restarting the quit journey is still progress.

World No Tobacco Day is not just about awareness but is a call to action. Choosing to quit today may be the single most important decision for a healthier and longer life.

(Dr Akshat Malik, Senior Consultant, Head & Neck Oncology, Apollo Hospital, Delhi)

According to the Indian Council of Medical Research - National Cancer Registry Programme (ICMR-NCRP), India reports about 220,000 new cases every year, and the common treatment procedure for this disease is chemotherapy, which comes with profound fatigue, hair loss, nausea, compromised immunity, and nerve damage.

The University College London led the Optima trial, which studied over 4000 patients with the disease in different parts of the world, and a low score on the genomic test could be mediated with only hormone therapy.

The trial’s chief investigator and a professor of breast oncology at UCL, Professor Rob Stein, explains that the study used tumour biology to guide decisions instead of relying on traditional clinical procedures.

The research had 4,429 women participants above the age of 40 years with hormone-positive breast cancer. These patients were then divided into two groups based on the genomic test results by the researchers, and one group with a higher risk was given chemotherapy along with hormone therapy, while the others were only treated with hormone therapy.

What Is Breast Cancer?

Breast cancer refers to the uncontrolled growth of the cells that are found along the inner lining of breast tissue. This out-of-control growth of cells leads to the formation of tumours. The tumour can be “invasive”, meaning that it spreads to the nearby tissues outside the breast, or “in situ”, where the tumour does not spread outside the breast region.

Usually, the “in situ” type of tumour is non-cancerous and non-life-threatening. However, in the case of invasive tumours, the cancerous cell mass can spread to the lymph nodes and further metastasise, that is, spread to other body parts. About 80% times the breast cancer cases are invasive. Hence, upon noticing symptoms like lumps, changes in breast shape, or abnormal nipple discharge, you must promptly consult a doctor.

While both men and women can develop it, in 99% of cases of breast cancer, women are seen to be affected by it. Only 0.5 to 1% of men are affected due to this condition. Furthermore, the condition is mostly prevalent in women aged 50 or older.