A new report published in The Lancet Diabetes & Endocrinology challenges the conventional definition of obesity, and urges a shift from the reliance on Body Mass Index (BMI) to a more nuanced approach. This is supported by over 50 global medical experts. The report also recommends splitting the term "obesity" into two categories: "Clinical obesity" and "Pre-clinical obesity". This aims to improve diagnosis and treatment for over a billion people worldwide living with obesity.
This applies to individuals whose obesity has progressed to a disease state, manifesting in organ damage, heart disease, type 2 diabetes, or other health complications. These individuals could also experience symptoms like breathlessness, joint pain, or impaired daily functioning. Treatment also involves medical interventions, including weight-loss medications or surgery.
Whereas the term "pre-clinic obese" refers to those who are overweight but not yet exhibiting health issues. While they may be at risk of developing obesity-related conditions, their organ function and overall health remain intact. What they need is preventive care, which includes dietary guidance, counselling, and regular monitoring to avoid and reduce future health risks.
The study, led by Professor Francesco Rubino from King's College London emphasizes that obesity is not one-size-fits-all condition. This means it should rather be treated as a spectrum as some individuals maintain normal organ function despite being classified as obese. There are others who may face severe health complications too. However, the current method of calculating obesity based on BMI often leads to misdiagnosis or inadequate care.
The report also states that BMI, while is useful for analyzing population trends, is a flawed unit of measuring individual health. Therefore, there is a need to redefine obesity, and healthcare professionals can provide more precise care by distinguishing those who need immediate medical intervention and those who require preventive strategies.
BMI is used to classify individuals as underweight, healthy weight, overweight, or obese based on their height and weight. It is calculated by dividing weight in kilograms by health in meters squared. However, there are reasons while it falls short.
•Muscle vs Fat: Athletes or muscular individuals often have high BMIs despite the low body fat
•Fat Distribution: BMI does not measure fat around the waist or organs, which could be more dangerous to one's health.
•Individual Health Variation: It also overlooks the specific health conditions such as heart diseases or diabetes, or any other, while evaluating a person's category in terms of weight.
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By redefining obesity, the study could transform the approach to diagnosis and treatment. It can focus on individual health risks rather than BMI alone. Healthcare providers can also offer tailored care. This also will ensure hat weight-loss medications like Wegovy or Mounjaro are prescribed only to those who genuinely require it.
As per Professor Louise Baur from the University of Sydney, a Children's obesity expert said that this redefinition allows both adults and children to receive more appropriate care while reducing over-diagnosis and unnecessary treatments.
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Mental health is a very important aspect of life, and the society at large, but a recent survey has shed light on the current state of mental health in adolescents and young adults. The survey of RAND was published in the journal JAMA Pediatrics. The survey finds that 1 in 5 adolescents and young people is using an AI chatbot for mental health.
The organization also did a similar survey back in 2025, but then about 13% of respondents admitted to using a chatbot for advice; that number has jumped up to 19% this year. The 63% of them confessed that they did not tell anyone about taking therapy from a chatbot.
Ryan McBain, a senior policy researcher at RAND and the lead author of the study, said, “It’s a sad number, because you’d hope that young people would have the sorts of supportive relationships that they would feel comfortable and empowered reaching out to those around them.”
McBain and his team asked people aged between 12 and 21 years about their use of AI chatbots, including ChatGPT, Google Gemini, or Character.AI, for mental health advice. They also asked whether the advice from the chatbots was helpful, and the majority of participants felt that the suggestions were useful.
Also Read: Study Finds Healthy Lifestyle Reduces Cardiovascular Risk In Childhood Cancer Survivors
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Over one million Americans have contracted chronic hepatitis B and are now forced to go through a lifelong treatment process. Though these treatment only helps in terminating the virus, the risk of liver cancer stays on, and the constant fear and torment remain. Now, a new study of a drug trial for hepatitis B patients has given hope to millions.
The trial saw 1 in 5 patients with chronic hepatitis B infection getting cured. The 24-week test had 1,838 patients from 29 countries in Asia, Europe, and North and South America. The research published in the New England Journal of Medicine concluded that 20% of patients got a functional cure, and no virus was detected in them after 48 hours.
The drug, bepirovirsen, is made by Ionis Pharmaceuticals and GlaxoSmithKline and can stop the virus from replicating itself while giving the immune system a chance to eradicate it. The treatment process will be done by administering an injection once a week. Notably, GlaxoSmithKline has already applied to the Food and Drug Administration for approval to market the drug.
Though there was an option of vaccination to prevent the disease, still, millions are infected. This effective functional cure option will be a great addition to the treatment of hepatitis B.
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Hepatitis B is a viral infection that affects the liver. Many adults can clear the virus after an acute infection. Some, however, go on to develop chronic hepatitis B, which increases the risk of liver cancer, liver failure, and cirrhosis, or permanent scarring of the liver.
Also Read: Study Finds Healthy Lifestyle Reduces Cardiovascular Risk In Childhood Cancer Survivors
The hepatitis B virus is highly contagious. It spreads when blood, semen, or other bodily fluids from a person who carries the virus enter the body of someone who is not infected.
Certain medical conditions, personal habits, and other circumstances can raise the risk, such as injection drug use or sexual contact, but the virus can infect anyone. Hepatitis B can also pass from an infected mother to her baby during childbirth, whether through a vaginal delivery or a C-section.
Vaccination is the most reliable way to prevent hepatitis B. The shots offer strong protection in infancy and continue to shield individuals well into adulthood. Babies usually receive a three-dose series.
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A healthy lifestyle is very crucial for any human being, but for cancer survivors, it's a must, as they tend to get various diseases, including cardiovascular ones. A recent study by the University of Gothenburg and St. Jude Children's Research Hospital also doubles down on this aspect. Their research reveals that a healthy lifestyle can significantly lower the risk of diseases like cardiovascular disease in childhood cancer survivors.
The study published in Nature Communications observed over 18,000 childhood cancer survivors for 30 days. The results clearly show that most of the chronic health problems among childhood cancer survivors revolve around lifestyle. Those with a habit of inactivity, obesity, smoking, and high alcohol intake are likely to catch diseases.
Aron Onerup, Pediatrician and Researcher at the University of Gothenburg and former Postdoctoral Fellow at St. Jude Children's Research Hospital in Memphis, said, "This reveals that lifestyle plays a much bigger role than previously thought. Unlike the treatments already given, the lifestyle can actually be changed."
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Another study published in JACC: CardioOncology with 2,300 cancer survivor participants finds that those who do not exercise regularly are 1.4 times more likely to contract a cardiovascular disease. The disease burden in childhood cancer survivors who do not exercise is twelve times more than that of the general population.
Aron Onerup, a Researcher within Pediatrics at Sahlgrenska Academy at the University of Gothenburg and a Specialist Physician at the Pediatric Cancer Center at Queen Silvia Children's Hospital, Sahlgrenska University Hospital, in Gothenburg, said, "This means that physical activity can make a big difference in reducing the extra risk that emerges after cancer treatment and modify the negative effects from cancer treatments. Our results provide strong scientific support for offering survivors structured support for healthy lifestyles."
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Cardiovascular diseases are the number one reason for death among women and men, according to the Centers for Disease Control and Prevention (CDC). Statistics show that about 44% women are living with heart diseases, and it is responsible for the death of 1 in 5 women.
There are many risk factors for heart diseases, like high blood pressure, which often goes undiagnosed in women. While studies have shown that women are more likely to live longer, even with diseases, a recent report shared how women are also more likely to have cardiovascular diseases than men.
According to the study published in the American College of Cardiology, even though women often try to live healthier, if they have issues like bad food habits or high blood pressure, their risk of heart disease goes up much more than it does for men.
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