Unexpected Weight Loss In Older Adults Could Be A Sign Of High Risk Dementia Onset

Updated Mar 1, 2025 | 01:51 PM IST

SummaryDementia is one of the most devastating diseases that causes people to lose their memories and much worse. Catching dementia early can help patients prepare for their inevitable future, but there are not many indicators as such. But this new study has revealed something that may help them!
(Credit-Canva)

(Credit-Canva)

Weight loss is usually considered a good thing, unexpected and extreme weight loss can be a sign of something in your body going very wrong. There could be some underlying issues that are causing your body to pull weight and nutrition from your muscles and body fat to keep you going. As you grow old, your limbs grow weaker, and same for your muscles, so you do lose some weight as you age, but losing a lot of it too quickly could be a sign of something much worse, Dementia. A recent study published in JAMA Network Open 2025 Cardiometabolic Trajectories Preceding Dementia in Community-Dwelling Older Individuals, has identified potential early indicators of dementia, including significant weight loss and specific digestive changes, appearing years before noticeable cognitive decline.

The study showed that people who later got dementia had their Body Mass Index, or BMI, go down faster than those who stayed healthy. BMI is a way to see if someone's weight is healthy for their height. This drop in BMI started happening many years before they were told they had dementia, sometimes as early as 11 years ago. Also, these people often started with a lower BMI to begin with. So, even though everyone's weight might change a little as they get older, the people who developed dementia had a much bigger and faster weight loss.

What Are Some Other Indicators Of Dementia?

Along with their BMI, the size of their waist also changed. People who ended up with dementia had smaller waist sizes, and this difference was noticeable about 10 years before they were diagnosed. This means that their bodies were changing in ways that showed up long before they or their doctors noticed any problems. So, not only was there weight loss, but also a loss of abdominal fat. This measurement is important because fat around the waist can be related to other health issues.

The study also found changes in their blood. Specifically, the "good" cholesterol, called HDL, went up in people who developed dementia. This increase happened about five years before they were diagnosed. It's tricky because HDL is usually seen as a good thing for your heart. But in this case, it seems like it might be a sign of changes happening in the brain. Scientists are still trying to understand why this happens.

Weight Loss Doesn’t Cause Dementia, Dementia Causes Weight Loss

When we see that people with dementia lose weight, it's easy to think that the weight loss is what caused dementia. But experts think it's the other way around. They call this "reverse causation." This means that the brain changes that cause dementia also cause people to lose weight. The brain changes can affect things like appetite, how the body uses food, and how people go about their daily lives. For example, people might forget to eat, have trouble making meals, or move around less.

While the study revealed a lot about different indicators of dementia and bodily changes, there are many limitations to the study. Everyone loses some weight as they get older. So, it's hard to know when weight loss is just a normal part of aging and when it's a sign of dementia. The study found that people with dementia lost weight faster, but it's still tricky to tell the difference in everyday life. Doctors need to look at other things, like memory tests, to figure out if someone's weight loss is a cause for concern.

If someone is losing weight without trying, and they're also having problems with their memory or thinking, it's important to talk to a doctor. It's not just about the weight loss; it's about the whole picture.

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Measles Cases Are Rising in US—Who Should Get A Booster Shot?

Updated Oct 1, 2026 | 06:12 PM IST

SummaryThe first measles vaccine was introduced in the US in 1963, but the formulation used between 1963 and 1967 was less effective than current versions. Adults vaccinated during that period may need another dose if they have not received a later measles vaccine.
Measles Cases Are Rising in US—Who Should Get A Booster Shot?

Credit: iStock

After eliminating measles in 2000, the US is now seeing a sharp increase in cases, with 3,659 confirmed cases reported as of September 24, 2026. Pennsylvania has reported five measles-related deaths this year, the first such deaths in the state in 35 years.

The number has risen significantly from previous years. The US reported 2,289 cases in 2025, compared with 285 in 2024 and just 85 cases in 2000.

Measles can cause serious complications, including pneumonia and encephalitis, or brain swelling, and can be fatal.

Two doses of the measles, mumps and rubella (MMR) vaccine can prevent measles by up to 97%, although breakthrough infections can still occur.

Around 95% of reported cases have been among unvaccinated people, although breakthrough infections have also been reported among people who were fully vaccinated. However, measles is not expected to be as severe in people who are vaccinated.

“Their illness will be much more mild and less likely to cause serious illness than if they had not received two vaccines,” Dr. Pia Fenimore, chief and vice chair of pediatrics at Penn Medicine Lancaster General Health.

Yet according to experts some people can take a booster shot to stay safe.

Who May Need a Measles Booster?

The first measles vaccine was introduced in the US in 1963, but the formulation used between 1963 and 1967 was less effective than current versions.

Adults vaccinated during that period may need another dose if they have not received a later measles vaccine.

People born before 1957 are generally considered to have presumptive evidence of immunity because measles circulated widely before routine vaccination, and most people in this age group were naturally infected.

Some people may need individualized vaccination guidance rather than standard recommendations, including:

  • People with uncertain vaccination status or no vaccination records
  • People who received an inactivated measles vaccine between 1963 and 1967
  • People with a weakened immune system
  • Pregnant people

A measles vaccine booster may also be considered for children who received only one MMR dose, high-risk adults such as healthcare workers or international travelers, and people whose testing shows they lack immunity.

Can A Blood Test Check Measles Immunity?

In cases where people do not remember or have no records of two-dose measles vaccination, an Immunoglobulin G (IgG) antibody test can help assess whether they have antibodies against measles.

If testing shows sufficient measles IgG antibodies, the person is considered immune. If immunity is not established, vaccination may be recommended based on their individual circumstances.

Why Adults Also Need To Be Alert

Measles is often associated with children, but adults can also become infected.

“We often forget about adults getting measles ... 38% to 40% of cases this year of measles have been in adults. Adults become infected at the same, if not higher, rates than children themselves ... in 2025, just over half of the measles hospitalizations were actually ... adults,” Dr. Gavin Harris, an infectious diseases physician with Emory Healthcare in Georgia and the associate medical director of the Serious Communicable Diseases Unit.

What If You Were Exposed To Measles?

Measles is highly contagious and can spread through even limited exposure to the virus. With the virus outbreak, it is likely for people to get exposed to it.

The measles vaccine remains the absolute best way to prevent disease.

A shot within three days of exposure to the contagious virus can help prevent the disease. Intravenous immunoglobulin (IVIG) given within six days can also provide protection after exposure.

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Type 1 Diabetes: Student Nearly Dies After Diet Advice To Stop Insulin; Why Insulin Is Essential

Updated Oct 1, 2026 | 05:10 PM IST

Summary​More than 9 million people worldwide are estimated to be living with Type 1 diabetes, including about 1.8 million children and adolescents. Type 1 diabetes occurs when the body cannot produce insulin. People with the condition therefore need insulin to control their blood glucose.
Type 1 Diabetes: Student Nearly Dies After Diet Advice To Stop Insulin; Why Insulin Is Essential

Credit: iStock

A 30-year-old law student with Type 1 diabetes was hospitalized with diabetic ketoacidosis (DKA) after allegedly being advised to stop insulin while following the “VRK Diet” promoted by social media personality Veeramachineni Ramakrishna, popularly known as VRK.

According to the complaint, the student had been living with Type 1 diabetes since 2018. He alleged that he came across VRK’s social media videos claiming that the diet could permanently cure conditions including Type 1 diabetes, cancer and kidney disease.

The student later visited the VRK Health Care Centre in Hyderabad in September 2025, where he alleged that he was orally advised to stop taking insulin. He said he paid around ₹26,000 for supplements and services at the center.

Two days later, he was admitted to a private hospital with DKA and severe dehydration, according to the complaint. He was later discharged.

Hyderabad police have booked Ramakrishna and another person in an alleged fake-doctor and fraud case.

Why Type 1 Diabetes Patients Must Never Stop Insulin

Also read: Gut Microbiome Linked To 3x Higher Type 1 Diabetes Risk In Children

More than 9 million people worldwide are estimated to be living with Type 1 diabetes, including about 1.8 million children and adolescents.

Type 1 diabetes occurs when the body cannot produce insulin. Insulin helps glucose move from the blood into cells, where it is used for energy. People with Type 1 diabetes therefore need insulin to control their blood glucose.

“Insulin is not optional in Type 1 diabetes,” Dr Sudhir Kumar, neurologist at Apollo Hospitals, Hyderabad, said in a post on X.

He advised people with Type 1 diabetes to never stop insulin on their own, including when they are unwell or unable to eat.

“Insulin doses may sometimes need adjustment, but this should be done with guidance from your diabetes team,” he said.

What Happens If Insulin Is Stopped?

The NHS UK explains that the human body needs insulin to break down glucose, i.e. sugar, to turn it into energy. People who have type 1 diabetes need insulin devices as their own body cannot produce it.

When the body does not have enough insulin, it cannot properly use glucose for energy. It starts breaking down fat instead, producing chemicals called ketones.

If ketones build up in the blood, they can cause diabetic ketoacidosis, a serious and potentially life-threatening complication.

DKA can develop when there is too little insulin, including when a person with Type 1 diabetes misses insulin doses.

Dr Kumar advised people with Type 1 diabetes to regularly monitor their blood glucose and check blood or urine ketones when indicated, particularly during illness or persistent high blood sugar.

Also read: H. pylori, HPV Among Five Infections Behind 1 In 8 Cancers Worldwide: Lancet

Warning Signs Of Diabetic Ketoacidosis

Dr Kumar said people with Type 1 diabetes should know the warning signs of DKA, including:

  • Excessive thirst
  • Frequent urination
  • Nausea or vomiting
  • Abdominal pain
  • Dehydration
  • Rapid or deep breathing
  • Drowsiness or confusion

Anyone with symptoms suggestive of DKA should seek urgent medical care.

Can Diet Or Supplements Replace Insulin?

Type 1 diabetes is an incurable condition. Dr Kumar warned people to be extremely cautious about claims that Type 1 diabetes can be “cured” through supplements, diets, herbs or alternative treatments that allow insulin to be stopped.

“Check the qualifications and registration of anyone giving medical advice. Social-media popularity is NOT a substitute for medical training,” he said.

“One wrong piece of advice can have life-threatening consequences. For Type 1 diabetes, evidence-based medical care and uninterrupted access to insulin are essential,” he added.

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Climate Change Is Affecting Skin Health Worldwide, Warns Study

Updated Oct 1, 2026 | 03:33 PM IST

Summary​More than half of low-income countries (55.6%) and lower-middle-income countries (52.5%) reported climate-related changes in skin disease.
Climate Change Is Affecting Skin Health Worldwide, Warns Study

Credit: iStock

Climate change is increasingly affecting human health, with the skin potentially among the first organs to show its effects, according to a new international study.

The analysis of 136 countries found that 42.6% reported climate-related changes in the prevalence, severity or both of skin diseases.

Presented at the European Academy of Dermatology and Venereology (EADV) Congress 2026, the study found that lower-income countries reported a greater burden.

Lower-Income Countries Report Greater Impact

Also read: Research Shows 39% GLP-1 Users Reported Nail Detachment: What Is Ozempic Nail

More than half of low-income countries (55.6%) and lower-middle-income countries (52.5%) reported climate-related changes in skin disease.

This compared with 43.8% of upper-middle-income and 28.3% of high-income countries.

Regional differences were also substantial:

  • Western Pacific: 64.7%
  • Eastern Mediterranean: 60%
  • South-East Asia: 60%
  • Europe: 16.1%

In Africa, 42.9% of respondents were unsure about climate change's impact on skin disease, suggesting gaps in surveillance and evidence.

Heat Rashes, Inflammatory Skin Diseases Rising

Among the 58 countries reporting climate-related effects, the most commonly reported changes included:

  • Heat rashes: 81%
  • Inflammatory skin diseases: 75.9%
  • Infectious skin diseases: 62.1%
  • Vector-borne diseases: 50%

“The most important finding from our study is that climate change is already associated with negative impacts on skin disease, and these effects disproportionately burden lower-income settings,” said Dr. Esther Freeman, study author and Associate Professor of Dermatology at Harvard Medical School.

How Climate Change Affects Skin

Read More: World Environment Day 2026: How Climate Change Is Increasing the Global Disease Burden | Explained

Rising temperatures, humidity, changing rainfall, air pollution and other environmental exposures can influence both the onset and severity of skin conditions.

Freeman said higher temperatures and humidity can increase sweating and skin irritation, while heat and air pollution may trigger or worsen inflammation.

“Shifts in temperature and rainfall can also affect the habitats of mosquitoes, ticks and other disease vectors, potentially allowing them to survive in places where they were previously uncommon,” she added.

Why Lower-Income Countries Face Greater Risks

The findings point to a wider climate-health disparity. Countries with fewer resources reported more climate-related changes in skin disease, despite generally contributing less to climate change.

These countries may also have fewer resources for disease surveillance, healthcare and climate adaptation.

The researchers called for stronger monitoring, greater awareness among healthcare professionals and locally tailored strategies.

Extreme Weather Can Trigger Skin Problems

The skin is constantly exposed to environmental conditions, making it particularly vulnerable to extreme weather events like flooding, wildfire smoke, etc.

  • Flooding: It can increase traumatic injuries and bacterial or fungal infections, while contaminated water can trigger contact dermatitis.
  • Wildfire smoke: Smoke and air pollution can worsen skin inflammation, including eczema.
  • Heat waves: Prolonged exposure can aggravate inflammatory skin conditions and, in severe cases, contribute to heat exhaustion and heat stroke.
  • Hot and humid weather: These conditions may increase some bacterial, fungal and viral infections.
Spending more time outdoors during extreme heat can further increase exposure to UV radiation, air pollution and insects.

As climate patterns change, the researchers said stronger surveillance and greater awareness of these emerging skin-health risks will be increasingly important.

Freeman stressed the need “to start treating skin health as part of climate-health preparedness.”

Key priorities include:

  • Strengthening surveillance
  • Improving climate-health education
  • Developing locally relevant adaptation strategies
  • Accounting for differences in healthcare resources.

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