Weight loss is usually considered a good thing, unexpected and extreme weight loss can be a sign of something in your body going very wrong. There could be some underlying issues that are causing your body to pull weight and nutrition from your muscles and body fat to keep you going. As you grow old, your limbs grow weaker, and same for your muscles, so you do lose some weight as you age, but losing a lot of it too quickly could be a sign of something much worse, Dementia. A recent study published in JAMA Network Open 2025 Cardiometabolic Trajectories Preceding Dementia in Community-Dwelling Older Individuals, has identified potential early indicators of dementia, including significant weight loss and specific digestive changes, appearing years before noticeable cognitive decline.

The study showed that people who later got dementia had their Body Mass Index, or BMI, go down faster than those who stayed healthy. BMI is a way to see if someone's weight is healthy for their height. This drop in BMI started happening many years before they were told they had dementia, sometimes as early as 11 years ago. Also, these people often started with a lower BMI to begin with. So, even though everyone's weight might change a little as they get older, the people who developed dementia had a much bigger and faster weight loss.

What Are Some Other Indicators Of Dementia?

Along with their BMI, the size of their waist also changed. People who ended up with dementia had smaller waist sizes, and this difference was noticeable about 10 years before they were diagnosed. This means that their bodies were changing in ways that showed up long before they or their doctors noticed any problems. So, not only was there weight loss, but also a loss of abdominal fat. This measurement is important because fat around the waist can be related to other health issues.

The study also found changes in their blood. Specifically, the "good" cholesterol, called HDL, went up in people who developed dementia. This increase happened about five years before they were diagnosed. It's tricky because HDL is usually seen as a good thing for your heart. But in this case, it seems like it might be a sign of changes happening in the brain. Scientists are still trying to understand why this happens.

Weight Loss Doesn’t Cause Dementia, Dementia Causes Weight Loss

When we see that people with dementia lose weight, it's easy to think that the weight loss is what caused dementia. But experts think it's the other way around. They call this "reverse causation." This means that the brain changes that cause dementia also cause people to lose weight. The brain changes can affect things like appetite, how the body uses food, and how people go about their daily lives. For example, people might forget to eat, have trouble making meals, or move around less.

While the study revealed a lot about different indicators of dementia and bodily changes, there are many limitations to the study. Everyone loses some weight as they get older. So, it's hard to know when weight loss is just a normal part of aging and when it's a sign of dementia. The study found that people with dementia lost weight faster, but it's still tricky to tell the difference in everyday life. Doctors need to look at other things, like memory tests, to figure out if someone's weight loss is a cause for concern.

If someone is losing weight without trying, and they're also having problems with their memory or thinking, it's important to talk to a doctor. It's not just about the weight loss; it's about the whole picture.

Most people pay little attention to their knees, legs and ankles until something goes wrong. Once pain sets in, even simple things like walking, climbing stairs, or standing for long can become a real challenge. Left unmanaged, lower limb pain gradually affects mobility, independence and quality of life.

What Is Usually Behind the Pain?

Knee pain commonly traces back to osteoarthritis, ligament injuries, cartilage damage, or years of wear. Pain in the leg can be caused by muscle injuries or conditions involving nerves and poor blood flow. The pain in the ankle is commonly caused by sprains, tendinitis, arthritis, or any injury that may have occurred earlier without complete healing.

Age, obesity, sedentary lifestyles, and constant joint injuries contribute silently to the degenerative condition of the joints.

Signs That Should Not Be Ignored

Persistent pain, swelling, stiffness, or discomfort that keeps getting worse deserves attention. If pain is disturbing your sleep, that is a clear signal to see a doctor.

Habits That Help Protect Your Joints

Walking downstairs puts considerable pressure on the knees, so limiting stair use where possible is sensible. Squatting, sitting on the floor and using Indian-style toilets place similar strain and are better avoided.

Staying active matters just as much. Regular household chores, walking, stretching and strengthening exercises, even 15 to 20 minutes a day, keep muscles strong and reduce the load on joints. Focusing on the adductor muscles around the knee is particularly effective in improving joint support.

Non-Surgical Options Worth Knowing

Surgery is not always the answer. Two non-surgical treatments carried out by a pain physician can make a meaningful difference.

Platelet-Rich Plasma therapy, or PRP, involves concentrating platelets from the patient's own blood and injecting them into the affected joint. In osteoarthritis, where cartilage gradually thins, PRP may help support regeneration and ease symptoms.

Radiofrequency Ablation, or RFA, uses a specialized needle to deliver targeted heat that interrupts the nerves responsible for sending pain signals to the brain. Relief typically lasts one to two years. The procedure is done as day care with no cuts, no stitches and no anesthesia required.

A concern many patients raise is that pain stops them from exercising or losing weight. Once pain is controlled through these treatments, walking and light activity become manageable again, which in turn supports weight loss and takes further pressure off the joints.

Custom Knee Supports

Off-the-shelf knee caps have limited effectiveness. A custom-made support, designed to redistribute body weight and reduce joint stress, works considerably better, especially in early arthritis. Many patients notice relief shortly after wearing one. They are an investment, but a worthwhile one that can reduce dependence on medication while the surrounding muscles gradually strengthen.

When to See a Doctor

If pain has lasted several weeks, is worsening, or is getting in the way of daily life, it is time to consult a specialist. Early diagnosis and the right treatment can protect joint function, restore mobility and often avoid the need for surgery.

(By Dr. Aanchal Sharma, Pain Physician, Principal Consultant and Head of Department, Department of Pain Medicine at BLK MAX Hospital, New Delhi)

Doctors in Mumbai are reporting a simultaneous rise in Covid-19, H1N1, commonly known as swine flu, and other respiratory viral infections.

As per the doctors, there is up to a 30 per cent surge in cases of COVID-19 and H1N1 as well as viral infections in the city. The doctors attributed the surge in infectious diseases to seasonal changes.

“We are currently observing a 20-30 per cent surge in Covid-19 and H1N1 (swine flu) respiratory viral infections in the city, mainly due to seasonal changes, increased humidity, and exposure to crowded places,” Dr. Aniket Mule, Consultant Internal Medicine, KIMS Hospital Thane, told HealthandMe.

Dr. Amit Saraf, Director of the Department of Internal Medicine, Jupiter Hospital, Thane, reported a rise in influenza-like illness (ILI) in the hospital.

“There is a seasonal rise in respiratory infection cases in Mumbai. Most of the people have routine viral infections, and around 10-15% of the people who are coming to OPDs have been coming positive for influenza-like illness (ILI) due to the changing weather,” Dr. Amit told HealthandMe.

Dr. Rohit Deshpande, Consultant Internal Medicine, Lilavati Hospital and Research Centre in Mumbai, told HealthandMe that the hospital is seeing a rise in swine flu cases.

“On average, 7 to 8 cases are being detected in the OPD daily. Most patients present with symptoms such as fever, cough, body ache, and fatigue”.

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What Are The Symptoms?

The experts reported that the commonly seen symptoms include:

• persistent fever,
• dry or wet cough,
• sore throat,
• fatigue,
• body ache
• mild breathlessness

Who Is More Vulnerable?

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Dr. Amit noted that people with chronic illnesses, elderly people, pregnant women and young children are still more susceptible to complications.

Dr. Rohit noted that people with diabetes and those with conditions such as COPD, asthma and heart diseases are also at higher risk of infection.

How To Prevent?

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The experts noted that most of the cases now are mild and can be handled with timely consultation, rest and supporting care.

But older people, pregnant women, children, and those with pre-existing health conditions should take extra care. Those with an ongoing fever, cough, sore throat, breathlessness, or extreme tiredness should seek immediate medical advice, Dr. Aniket said.

“Simple preventive measures like hand hygiene, use of masks in crowded places, proper hydration and timely medical consultation can help a lot in reducing the risk of complications,” he told HealthandMe.

Preventive measures for the general population include:

• Avoid self-medication
• If you experience a persistent cough or breathing difficulties, consult a doctor regarding the need for anti-viral or anti-allergy medications.
• Get vaccinated every year to boost Immunity and reduce the risk of infection.
• Avoid crowded and dusty places, redevelopment areas, or places with pigeon droppings.
• Use hand sanitizer, wash your hands frequently and thoroughly, and wear a mask in crowded or dusty environments
• Do warm saline gargles with salt or betadine twice or thrice a day
• Take steam hydration if required too
• Maintain hydration to avoid weakness, fatigue, or headache
• To boost immunity - consume green leafy vegetables & Vitamin C-rich fruits along with Vitamin D supplements

The common perception about varicose veins is that they are merely an aesthetic or cosmetic problem. Varicose veins are indeed enlarged, twisted blood vessels that many people believe are not life-threatening. But the reality is that the condition may be a symptom of something more serious.

The disease manifests itself through insufficient blood supply in the body caused by faulty valves. As the blood vessels cannot effectively move the blood from the veins back to the heart, the blood tends to accumulate in the veins themselves. Other symptoms may include pain, heaviness, swelling, and skin sores in severe cases.

What Are The Causes Of Varicose Veins?

Varicose veins don’t develop overnight; they are usually the result of multiple underlying factors that gradually affect vein health and blood flow:

1. Valve dysfunction and poor circulation: Healthy veins rely on tiny valves to prevent backflow. When these valves weaken, blood starts collecting in the veins, leading to increased pressure and visible swelling.

2. Prolonged standing or sitting: These days, occupations require long hours of standing, which can hinder proper blood circulation and increase the risk.

3. Hormonal changes: Hormonal fluctuations during pregnancy, menopause, or while using hormonal therapies can relax vein walls, making them more prone to dysfunction.

4. Genetics: A family history of varicose veins significantly raises the likelihood of developing them, indicating a hereditary component in vein wall strength and valve efficiency.

5. Obesity and lack of physical activity: Excess body weight puts additional pressure on veins, while a sedentary lifestyle reduces the efficiency of blood circulation, leading to vein damage over time.

6. Ageing: As people age, veins lose elasticity, and valves may wear out, making older adults more susceptible to developing varicose veins.

What Are The Tips To Take Care Of?

People can manage or reverse varicose veins by:

• Making sure blood is circulating well in the body: An inactive lifestyle or standing for long periods can lead to increased risks of vein disease. Exercise and movement, along with raising the legs, will ensure that blood continues circulating well.

• Maintaining a healthy weight: Obesity can lead to increased pressure on the veins of the legs. Maintaining a healthy body weight is important to avoid and treat varicose veins.

• Wear compression stockings: Compression stockings apply gentle pressure to the veins, which enables them to circulate blood effectively and avoid swelling and other conditions.

• See a vein specialist if necessary: In cases of persistent pain, discoloration of skin, severe itching, or sores that don't heal, it is advised to see a vein specialist, as these symptoms could signal something worse.

How Can It Be Treated?

Varicose vein treatment procedures have become much easier in the modern world. Varicose veins can now be treated with minimally invasive procedures that address the problem at its root cause. These minimally invasive treatments include EVLT (Endovenous Laser Treatment), Radiofrequency Ablation (RFA), and glue ablation. A laser fibre is inserted into the varicose vein during this operation, where it effectively closes it off.

Blood is automatically redirected through other veins after this treatment, which is relatively quick and involves local anesthesia. Patients generally recover within one day. However, EVLT is much less painful, safer, and does not involve leaving scars behind.

Varicose veins are often a symptom of vein disease and thus not just a cosmetic problem. They can be a visible sign of an underlying circulatory issue. Paying attention to early symptoms and seeking medical advice can help prevent complications and improve overall vascular health. Preventing further problems is easy when one knows what to do.