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Weight loss is usually considered a good thing, unexpected and extreme weight loss can be a sign of something in your body going very wrong. There could be some underlying issues that are causing your body to pull weight and nutrition from your muscles and body fat to keep you going. As you grow old, your limbs grow weaker, and same for your muscles, so you do lose some weight as you age, but losing a lot of it too quickly could be a sign of something much worse, Dementia. A recent study published in JAMA Network Open 2025 Cardiometabolic Trajectories Preceding Dementia in Community-Dwelling Older Individuals, has identified potential early indicators of dementia, including significant weight loss and specific digestive changes, appearing years before noticeable cognitive decline.
The study showed that people who later got dementia had their Body Mass Index, or BMI, go down faster than those who stayed healthy. BMI is a way to see if someone's weight is healthy for their height. This drop in BMI started happening many years before they were told they had dementia, sometimes as early as 11 years ago. Also, these people often started with a lower BMI to begin with. So, even though everyone's weight might change a little as they get older, the people who developed dementia had a much bigger and faster weight loss.
Along with their BMI, the size of their waist also changed. People who ended up with dementia had smaller waist sizes, and this difference was noticeable about 10 years before they were diagnosed. This means that their bodies were changing in ways that showed up long before they or their doctors noticed any problems. So, not only was there weight loss, but also a loss of abdominal fat. This measurement is important because fat around the waist can be related to other health issues.
The study also found changes in their blood. Specifically, the "good" cholesterol, called HDL, went up in people who developed dementia. This increase happened about five years before they were diagnosed. It's tricky because HDL is usually seen as a good thing for your heart. But in this case, it seems like it might be a sign of changes happening in the brain. Scientists are still trying to understand why this happens.
When we see that people with dementia lose weight, it's easy to think that the weight loss is what caused dementia. But experts think it's the other way around. They call this "reverse causation." This means that the brain changes that cause dementia also cause people to lose weight. The brain changes can affect things like appetite, how the body uses food, and how people go about their daily lives. For example, people might forget to eat, have trouble making meals, or move around less.
While the study revealed a lot about different indicators of dementia and bodily changes, there are many limitations to the study. Everyone loses some weight as they get older. So, it's hard to know when weight loss is just a normal part of aging and when it's a sign of dementia. The study found that people with dementia lost weight faster, but it's still tricky to tell the difference in everyday life. Doctors need to look at other things, like memory tests, to figure out if someone's weight loss is a cause for concern.
If someone is losing weight without trying, and they're also having problems with their memory or thinking, it's important to talk to a doctor. It's not just about the weight loss; it's about the whole picture.
Credit: WHO
Breastfeeding is important not only for babies' health and nutrition but also for protecting mothers from serious diseases, the World Health Organization (WHO) said.
It urged governments to strengthen access to services and interventions that support breastfeeding as part of World Breastfeeding Week, observed annually from August 1–7.
The 2026 theme, "Breastfeeding for a Sustainable Start in Life: Strengthen What Works," focuses on tracking progress, evaluating impact, and scaling proven approaches that improve breastfeeding outcomes.
"Scaling up breastfeeding could prevent almost 400,000 child deaths and around 140,000 maternal deaths each year," said UNICEF Executive Director Catherine Russell and WHO Director-General Dr. Tedros Adhanom Ghebreyesus in a joint statement.
"Every US$1 invested in breastfeeding promotion generates an estimated US$59 in economic returns through lower health-care costs, improved cognitive development, higher educational attainment, and increased lifetime earnings," they added.
The experts noted that breastfeeding is one of the simplest and most powerful ways to protect a child's health. It provides infants and young children with essential nutrition, boosts immunity, helps protect against serious illnesses, and supports cognitive development.
For mothers, breastfeeding also offers significant health benefits by reducing the risk of noncommunicable diseases such as breast and ovarian cancers, and type 2 diabetes.
The WHO said breastfeeding rates have improved globally due to sustained investments in policies and programs supporting mothers and families.
Exclusive breastfeeding during the first six months increased from around 37 per cent in 2012 to more than 47 per cent today. Over the past five years, the prevalence of breastfeeding up to two years of age has risen from 38 per cent to 50 per cent.
Despite these gains, the WHO said many countries continue to lag behind global targets.
"Coverage of services supporting breastfeeding remains low, policies are inconsistently enforced, and service quality is often inadequate, especially in low-income, fragile, and humanitarian settings," the WHO said.
The agency noted that cost-effective interventions include skilled breastfeeding support within health systems, community-based counselling, maternity protection policies, and protection from the exploitative marketing of commercial milk formulas.
WHO and UNICEF called on governments, health systems, workplaces, communities, civil society organizations, and families to strengthen the "Warm Chain of Support" for breastfeeding.
During World Breastfeeding Week, the agencies urged countries to:
"Breastfeeding is vital. By investing in proven solutions, we can give every child the best possible start in life and ensure every mother gets the care and services she needs," the agencies said.
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A new study published in The Lancet Regional Health–Southeast Asia has found that India accounts for 68% of all childhood cancer cases in the SAARC region.
While the country's large child population contributes to the high numbers, experts say underdiagnosis and incomplete cancer registration may mean the actual burden is even greater.
An international team of researchers, including from the US, India, and Canada, estimated that nearly 37,700 children aged up to 14 years were diagnosed with cancer across South Asia in 2022, with 17,700 deaths reported. India alone accounted for an estimated 25,939 cases and 12,028 deaths.
The researchers noted that because cancer registration remains incomplete, particularly in rural areas, the true number of childhood cancer cases in India could exceed 50,000 annually.
India is home to more than 380 million children, accounting for nearly 69% of the child population in the SAARC region. This naturally contributes to the country's higher share of childhood cancer cases and deaths.
However, experts emphasize that population size is only part of the explanation. Delayed diagnosis, limited access to specialized treatment, and gaps in cancer registration continue to affect both disease estimates and patient outcomes.
Dr. Narendra Agrawal, a leading Hematologist and Bone Marrow Transplant Physician and Senior Consultant and Unit Head of Haemato-Oncology at Rajiv Gandhi Cancer Institute & Research Centre, told HealthandMe that childhood cancer remains a major public health concern in India.
"Current estimates suggest that around 70,000–80,000 children and adolescents develop cancer each year, although the exact number remains uncertain due to expanding cancer registration systems". The most common childhood cancers in India include:
Unlike many adult cancers, most childhood cancers do not have a clearly identifiable or preventable cause. Dr. Agrawal explained that, in most children, cancer develops because of genetic changes that occur during early development. These changes are usually not linked to lifestyle factors or inherited from parents.
Although the causes of most childhood cancers remain unclear, some well-established risk factors include:
Dr. Agrawal said India's substantial childhood cancer burden is largely driven by its population size. However, improving outcomes requires addressing several systemic challenges.
Key issues include:
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Marketed as a "harmless" alternative to cigarette smoking, vaping is increasingly emerging as a health concern, particularly for lung health, doctors warned ahead of World Lung Cancer Day on August 1.
Traditional cigarettes remain strongly linked to lung cancer, chronic obstructive pulmonary disease (COPD), and several other life-threatening illnesses. However, growing laboratory, animal, and population studies suggest vaping may also damage lung tissue, alter DNA, and potentially increase lung cancer risk—especially among people who both smoke and vape.
A recent study published in the peer-reviewed journal ERJ Open Research found that vaping may offer far less protection than many users believe when it comes to cardiovascular fitness, breathing efficiency, lung function, and blood vessel health in young adults.
"E-cigarettes are often advertised as a safer choice and as a way to help people quit smoking. But the evidence behind these claims is weak. We still don't fully know what long-term damage e-cigarettes can do to the lungs, including whether they can cause lung cancer," Dr. Shiba Kalyan Biswal, Head of Pulmonology at Shalby International Hospital, Gurugram, told HealthandMe.
The vapor produced by e-cigarettes contains several harmful chemicals, including substances that can damage cells and DNA—the genetic material inside the body's cells.
Animal studies have found that mice exposed to e-cigarette vapor for about a year developed a type of lung cancer. Ingredients commonly used in e-cigarette liquids, such as propylene glycol and benzoic acid, may also irritate cells and trigger inflammation in the lungs.
"There have also been outbreaks of a serious vaping-related lung disease that has sent people to hospital with severe breathing problems. This shows that the risks of vaping can be unpredictable, especially when products are poorly regulated or contain unknown ingredients," Dr. Biswal explained.
She urged doctors to routinely ask patients about e-cigarette use, particularly those with breathing problems or those at higher risk of lung cancer.
"Since evidence suggests that e-cigarettes add to the risk for people who used to smoke, it may be worth including vaping history when deciding who needs lung cancer screening," she said.
According to Dr. Biswal, lung cancer risk appears to be even higher among people who use both e-cigarettes and conventional cigarettes, often referred to as "dual users."
Many smokers who turn to e-cigarettes intending to quit end up continuing to use both products rather than switching completely.
"This means they stay addicted to nicotine and may be exposed to even more harmful substances."
Doctors are also reporting more lung cancer cases among young people who have never smoked, particularly women.
Indoor air pollution, biomass fuel exposure, second-hand smoke, occupational hazards, and genetic susceptibility are increasingly contributing to the disease, said Dr. Akshay Budhraja, Senior Consultant and Head of Respiratory and Sleep Medicine at Aakash Healthcare.
"It's no longer just the lifelong smoker in his sixties—we are seeing younger patients, more women, and a growing number who have never touched a cigarette. Air quality, occupational exposure and genetic predisposition are all playing a bigger role than they used to, and that means our screening approach has to widen well beyond the traditional smoker profile," Dr. Budhraja said.
Experts said early detection through low-dose CT screening remains crucial for high-risk individuals. However, symptoms such as a persistent cough or breathlessness are often mistaken for pollution-related irritation or a lingering infection, leading many people to delay getting screened.
They also noted that lung cancer affects more than the lungs, with potential impacts on men's sexual health and women's reproductive health.
According to the World Health Organization (WHO), lung cancer remains one of the world's biggest public health challenges due to its high incidence and mortality. In 2024, it was the leading cause of cancer-related deaths globally, with an estimated 2.6 million new cases and 1.8 million deaths.
Lung cancer develops when abnormal cells grow uncontrollably in the lungs. Treatment depends on a person's medical history and the
stage of the disease.
The doctors stressed that avoiding tobacco remains the most effective way to reduce lung cancer risk.
"Smokers face nearly 20 times the risk of non-smokers, though the rising non-smoker caseload complicates that picture," said Dr. Budhraja. "Second-hand smoke is the third leading cause of lung cancer among non-smokers; radon gas, seeping in from soil, is the leading one, and home testing kits can catch it."
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