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Weight loss is usually considered a good thing, unexpected and extreme weight loss can be a sign of something in your body going very wrong. There could be some underlying issues that are causing your body to pull weight and nutrition from your muscles and body fat to keep you going. As you grow old, your limbs grow weaker, and same for your muscles, so you do lose some weight as you age, but losing a lot of it too quickly could be a sign of something much worse, Dementia. A recent study published in JAMA Network Open 2025 Cardiometabolic Trajectories Preceding Dementia in Community-Dwelling Older Individuals, has identified potential early indicators of dementia, including significant weight loss and specific digestive changes, appearing years before noticeable cognitive decline.
The study showed that people who later got dementia had their Body Mass Index, or BMI, go down faster than those who stayed healthy. BMI is a way to see if someone's weight is healthy for their height. This drop in BMI started happening many years before they were told they had dementia, sometimes as early as 11 years ago. Also, these people often started with a lower BMI to begin with. So, even though everyone's weight might change a little as they get older, the people who developed dementia had a much bigger and faster weight loss.
Along with their BMI, the size of their waist also changed. People who ended up with dementia had smaller waist sizes, and this difference was noticeable about 10 years before they were diagnosed. This means that their bodies were changing in ways that showed up long before they or their doctors noticed any problems. So, not only was there weight loss, but also a loss of abdominal fat. This measurement is important because fat around the waist can be related to other health issues.
The study also found changes in their blood. Specifically, the "good" cholesterol, called HDL, went up in people who developed dementia. This increase happened about five years before they were diagnosed. It's tricky because HDL is usually seen as a good thing for your heart. But in this case, it seems like it might be a sign of changes happening in the brain. Scientists are still trying to understand why this happens.
When we see that people with dementia lose weight, it's easy to think that the weight loss is what caused dementia. But experts think it's the other way around. They call this "reverse causation." This means that the brain changes that cause dementia also cause people to lose weight. The brain changes can affect things like appetite, how the body uses food, and how people go about their daily lives. For example, people might forget to eat, have trouble making meals, or move around less.
While the study revealed a lot about different indicators of dementia and bodily changes, there are many limitations to the study. Everyone loses some weight as they get older. So, it's hard to know when weight loss is just a normal part of aging and when it's a sign of dementia. The study found that people with dementia lost weight faster, but it's still tricky to tell the difference in everyday life. Doctors need to look at other things, like memory tests, to figure out if someone's weight loss is a cause for concern.
If someone is losing weight without trying, and they're also having problems with their memory or thinking, it's important to talk to a doctor. It's not just about the weight loss; it's about the whole picture.
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As summer heat intensifies both in India and globally, many people may experience unusual heart sensations such as a racing heartbeat, chest fluttering, skipped beats, or pounding sensations, even while resting.
Speaking to HealthandMe, Dr. L.K. Jha, Associate Director and Head Unit-II, Cardiology, Asian Hospital, Faridabad, said that heatwaves can significantly increase the risk of heart palpitations.
Normal healthy people may experience occasional mild palpitations due to heat exposure, which usually resolve with rest, fluids, and cooling off. However, experts warn that when palpitations are accompanied by symptoms such as chest pain, loss of consciousness, shortness of breath, extreme light-headedness, or recurring episodes while resting, they may indicate an underlying cardiac rhythm issue requiring medical attention.
“The association between heatwaves and palpitations occurs more frequently than people think,” Dr. Jha said.
The human body constantly works to maintain a stable internal temperature.
During extreme heat, blood vessels dilate to release heat through the skin, while the heart pumps faster to circulate blood and cool the body. According to Dr. Jha, this additional strain on the cardiovascular system can make the heartbeat feel stronger or irregular, especially in people sensitive to heat.
Also read: Heatwave In India: Temperatures Continuously Rising; Stay Hydrated, Says PM Modi
Dr. Jha explained that dehydration is one of the biggest contributors to heat-related palpitations.
Excessive sweating leads to the loss of water and essential electrolytes such as sodium, potassium, and magnesium, all of which are crucial for maintaining a normal heart rhythm.
“Dehydration can lower blood pressure, forcing the heart to beat faster, which may cause dizziness, shakiness, or pounding sensations,” he said.
Heatwaves may also worsen existing conditions such as anxiety, thyroid disorders, anemia, diabetes, and heart disease, increasing the likelihood of palpitations.
Certain medications, including blood pressure drugs, diuretics, asthma inhalers, as well as excessive consumption of caffeine or energy drinks, may further contribute to irregular heartbeats during hot weather, Dr. Jha told HealthandMe.
Sleep disturbances caused by hot nights can also trigger stress hormones in the body, potentially leading to rapid heartbeat episodes or fluttering sensations.
Also read: Climate Change Fueling Chikungunya Spread To Europe, North America, Warns Study
Dr. Jha noted that occasional mild palpitations due to heat exposure are common and often improve with rest, hydration, and cooling down.
Doctors recommend drinking fluids regularly, replenishing electrolytes through coconut water, buttermilk, lemon water, or Oral Rehydration Salts (ORS), avoiding prolonged sun exposure, and limiting caffeine and alcohol intake during heatwaves.
However, persistent or severe palpitations may indicate a more serious condition.
“If palpitations are accompanied by chest pain, shortness of breath, fainting, severe light-headedness, or repeated episodes while resting, immediate medical evaluation is necessary,” Dr. Jha warned.
He added that some heat-related palpitations may actually signal an underlying heart rhythm disorder requiring treatment.
Meanwhile, the India Meteorological Department (IMD) has issued a yellow alert for heatwave conditions in Delhi.
Heatwave conditions in the national capital are expected to continue till tomorrow, with maximum temperatures remaining between 44 and 46 degrees Celsius.
The IMD forecast also includes relief in the form of thunderstorms, dust storms, and light rainfall from May 28 evening onwards.
At the same time, European countries like France, the United Kingdom, Spain, and Germany are experiencing early heatwaves and record-breaking conditions.
The sweltering heat conditions have affected scores of people, reportedly resulting in the deaths of about seven people in France. The unusually high temperatures early in May are being triggered by a phenomenon called a “heat dome”.
As a result, southern and southwestern regions, including Portugal, Spain, and France, will experience daytime temperature highs of 38°C. The majority of France is under a moderate to high temperature warning, while Germany and the UK are witnessing maximum temperatures exceeding 30°C, the Euronews reported.
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The human body thrives on essential metals, but excessive exposure can cause a variety of issues for them in the long run, and this very fact has come to light in a recent study done by a research team at the Icahn School of Medicine at Mount Sinai Hospital. The paper reveals the detrimental impact of getting exposed to toxic metals early in life.
Drs. Manish Arora, Elza Rechtman, and Megan Horton at the Icahn School of Medicine at Mount Sinai Hospital thoroughly studied the mental effects in infants after early exposure to toxic metals. The study was published in Science Advances.
The research team studied the teeth of 489 infants aged 8 to 14 years old. As teeth grow in layers, and each layer can provide data on metal exposure, the researchers measured exposure to lead, lithium, barium, copper, manganese, magnesium, tin, zinc, and strontium.
The study also monitored 395 children for symptoms relating to anxiety, depression, hyperactivity, and attention, and magnetic resonance imaging (MRI) was used to examine 191 children.
Metals like zinc, magnesium, and manganese are very important for growth and health, but overexposure to these metals in children can cause harm.
Childhood is the time for mental growth in children, but this is the same time span when they get exposed to toxic metals as well. From food to inhaling tobacco smoke or exposure through touch, there are many ways a child gets near those adversarial metals and causes harm to themselves.
The results of the study show that exposure to heavy metals mainly happens between 6 and 9 months after birth. They also claim that the excessive metal exposures during key periods of brain development can have long-lasting effects.
Also Read: How To Get Rid Of Heavy Metals In Your Body?
Reducing exposure to heavy metals can be achieved through simple lifestyle and dietary changes. This includes switching to greener diets and replacing household products. High-quality fish can help minimize mercury ingestion, while cilantro, seaweed, and leafy greens are known to trap and remove toxins from the body. Aluminium-free deodorants and titanium-free makeup and toothpaste are also recommended.
For a more intensive detox, using high-quality supplements alongside drinking at least two litres of water daily can help flush heavy metals. Armistead explains that these supplements aid the body in moving heavy metals from cells to the lymphatic system, which then transports them into the bloodstream for filtration by the liver and kidneys. The toxins are ultimately excreted via urine or bowels.
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Even as climate change is driving mosquitoes north, a new study warned that Europe and North America can be new hotspots for the chikungunya virus.
Alarmingly, the research indicated that 139 countries face risk, covering 21.26 per cent of global land area for chikungunya, a mosquito-borne viral disease.
Further, the findings published in the journal Frontiers in Cellular and Infection Microbiology suggest that climate-driven vector expansion has significantly broadened the geographic scope of the CHIKV threat.
Also Read: Meningitis Outbreak In Sri Lanka: 200 Reported Cases, Authorities Issued Special Guidelines
“We show that under climate change models, the virus will further expand northward into temperate regions, especially northeastern North America, central Europe, and East Asia,” said Dr Ye Xu, from Zhejiang Chinese Medical University, China.
Chikungunya is a viral illness transmitted to humans primarily through the bite of infected Aedes aegypti and Aedes albopictus mosquitoes.
Also Read: Climate Change Fueled Rising Salmonella Drug Resistance Over Decades: The Lancet Study
As the primary vectors of chikungunya, Aedes aegypti and Aedes albopictus are highly influenced by climate conditions.
These mosquitoes thrive in warm and humid environments, with temperature playing a major role in their breeding, survival, and ability to spread the virus.
The rising temperatures can accelerate larval development, increase mosquito reproduction, and shorten the virus’s incubation period inside the mosquito, making transmission more efficient.
In the study, the researchers explained that stable temperature patterns and seasonal variations are especially important for Aedes aegypti. The species is highly sensitive to colder temperatures, with egg hatching rates dropping significantly at around 12°C. This limits how far the mosquito can spread into cooler regions.
However, climate change and warming temperatures are making previously unsuitable regions in Europe and North America more favorable for these mosquito species, raising concerns about the growing risk of chikungunya outbreaks, the team said.
“Because this mosquito can tolerate cooler conditions better than the yellow fever mosquito, warming may allow it to establish in places that used to be too cold,” said Dr Yang Wu, Guangzhou Customs Technology Center, China.
“When suitable mosquitoes become established, the chance of local chikungunya transmission increases.”
Read More: 16 Million Indians Die Due To Hypertension Every Year: AIIMS Doc
In 2025, there were 502,264 reported chikungunya cases globally, accounting for 186 deaths across 41 countries and territories, according to the Pan American Health Organization.
This disease burden is projected to escalate under climate change, which is profoundly altering the distribution patterns of infectious diseases, the researchers noted.
“The public does not need to panic, but health systems should prepare early,” warned Dr Xu.
The researchers recommended that these regions implement proactive entomological surveillance and adaptive public health infrastructure by 2040 to mitigate the threat of emerging arboviral epidemics.
Among the proposed measures, researchers include
Most symptoms are generally self-limiting and last for 2–3 days. The disease is characterized by
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