Oats (Credit: Canva)
Ozempic works by mimicking the hormone GLP-1, which suppresses hunger and regulates blood sugar levels. All semaglutide medications work like that. These drugs are great for those trying to shed extra pounds in their body, however, there's a catch. All of these blockbuster weight loss drugs are synthetic and not sustainable in the long run. But wait, what if I told you that researchers have found a component in your everyday breakfast that can do just the same?
Researchers also tested several types of dietary fibre, including dextrin, pectin, resistant starch, and cellulose. However, none of these fibres showed the same impact on weight reduction or fat loss as beta-glucan, despite significantly altering the gut microbiome. "We know that fibre is important and beneficial; the problem is that there are so many different types of fibre," explained Frank Duca, a biomedical scientist from the University of Arizona. The study aimed to determine which type of fibre is most effective for weight loss and glucose regulation, providing valuable insights for consumers and the agricultural industry.
Dietary fibre is a plant-based nutrient found in whole grains, fruits, and vegetables. It serves as the primary energy source for beneficial gut bacteria, playing a vital role in digestive health. Despite its importance, less than 5 per cent of people in the US consume the recommended 25–30 grams of fibre per day. A high-fiber diet is known to be protective against weight gain. Foods rich in fibre tend to have lower energy density, meaning they provide fewer calories per gram of food. This allows individuals to consume the same volume of food while reducing their caloric intake. Additionally, fibre-rich foods are often bulky and filling, promoting satiety.
Soluble fibre, such as beta-glucan, forms a gel-like substance in the digestive tract, slowing stomach emptying and extending the feeling of fullness. This delayed digestion also results in a slower absorption of sugars, helping to maintain stable blood sugar levels and prevent insulin spikes, which have been linked to obesity and an increased risk of diabetes.
Credit: Opthalmology Journal
Doctors in India’s southern state of Tamil Nadu surgically removed a fully developed canine tooth from the upper eyelid region of a 16-year-old boy. They described the case as the first reported instance of an ectopic tooth in the upper part of the eye socket.
The case was reported by specialists at Aravind Eye Hospital in Madurai in the journal Ophthalmology.
The teenager visited the hospital with painless swelling of his left upper eyelid that had lasted a month. He had no history of injury to the area.
During the examination, doctors noticed two firm, whitish projections beneath the swollen area near the inner side of the upper eyelid, the experts shared in the paper.
A computed tomography (CT) scan revealed a dense structure resembling a tooth, with a crown and root, originating from the roof of the left eye socket. It extended towards the tissues in front of the orbital septum, a thin barrier separating the eyelid from the deeper eye socket, and protruded outwards with two tooth-like points on its surface.
The projections' appearance and texture raised the possibility that they were teeth. Dr. Meghana Tanwar, a medical consultant at Aravind Eye Hospital, told Live Science that they had a “fairly smooth surface and were hard on palpation.”
The doctors surgically removed the structure. Examination confirmed that it was a mature canine tooth without teratomatous elements, consistent with an ectopic tooth in the upper part of the eye socket.
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An ectopic tooth develops or emerges in an abnormal location. Some remain within the mouth but appear outside their usual positions in the dental arch, while others develop outside the normal arrangement of teeth.
The latter is particularly unusual. In this teenager's case, the tooth was located in the upper orbital region rather than within the normal dental arch.
Before confirming the diagnosis, doctors considered whether the projections could be associated with a teratoma, a type of tumor that can contain different tissues, including bone and tooth tissue. They also considered whether a foreign object might be lodged in the eyelid.
Imaging and examination of the removed structure helped establish that it was a mature tooth rather than tissue associated with a teratoma.
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Ectopic teeth have been documented in several locations, including the nasal cavity, chin and maxillary sinus, an air-filled cavity within the cheekbone. Previous reports have also described teeth in the lower part of the eye socket.
However, the doctors said they could not find an earlier report of an ectopic tooth in the superior orbit, the upper region of the eye socket.
“To the best of our knowledge this is the first and only ectopic tooth reported in the superior orbit,” Tanwar told Live Science.
“This was a first not just for us but the world over,” she said of the case. “We were very surprised by it.”
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The doctors could not determine why the tooth developed in this unusual location.
Possible explanations for ectopic tooth development include abnormalities during development, genetic factors, infections and physical trauma. However, the cause in this case remains unknown.
Imaging did not reveal any additional ectopic teeth. Tanwar said the likelihood of the teenager developing another such tooth was low.
Credit: iStock
Pancreatic cancer is one of the cancers doctors find particularly difficult to detect early. The pancreas lies deep inside the abdomen, and early disease may cause few or vague symptoms. By the time symptoms such as jaundice, unexplained weight loss, abdominal or back pain or persistent digestive problems become apparent, the disease may already be advanced.
This is why the findings of a new international study on PANXEON, an investigational liquid biopsy, are attracting attention. Published in Nature Medicine, the study evaluated 1,785 people across four countries and explored whether a blood sample could identify early pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer.
The principle behind the test is relatively simple. Cancer cells release molecular material into the bloodstream. PANXEON looks at a group of tiny molecules called microRNAs, including those carried inside microscopic packages called exosomes. These molecules can provide molecular clues about what is happening in the pancreas. The test combines this microRNA signature with CA19-9, a blood marker already used in pancreatic cancer, particularly for monitoring patients, although CA19-9 alone is not suitable as a general screening test.
Also read: Dr Rachna Shroff: Indian-American Cancer Researcher Who Turned Her Diagnosis Into Advocacy
In the study, the microRNA test detected early-stage pancreatic cancer with a sensitivity of 83.8%. When combined with CA19-9, PANXEON reached 86.8% sensitivity for stage I-II disease. Importantly, false-positive rates were 3.2% among low-risk controls and 15.6% among high-risk controls. The researchers also reported that the test showed potential for identifying high-grade dysplasia in people with high-risk pancreatic cysts.
For India, this research is relevant because pancreatic cancer, although less common than several other major cancers, represents a significant clinical challenge. India’s National Cancer Registry Programme estimated about 21,000 pancreatic cancer cases in 2022. Globally, GLOBOCAN estimated more than 510,000 new cases in the same year.
But there is an important caveat: PANXEON is not yet a routine screening test. There is currently no standard screening test recommended for people at average risk of pancreatic cancer. Screening is generally considered for selected high-risk individuals, such as those with significant family histories or certain inherited genetic risks.
The new findings therefore represent a promising research direction, rather than a test people should independently seek out today. A useful early-detection test must work reliably in much larger, diverse populations and demonstrate that detecting cancer earlier actually improves outcomes.
For patients and doctors, however, the concept is important. Instead of waiting for a tumour to become large enough to produce obvious symptoms or visible changes on imaging, researchers are increasingly asking whether the molecular footprints of cancer can be detected in a simple blood sample. PANXEON is one more step towards answering that question.
Credit: iStock
I have often heard a familiar bedtime story: “I picked up my phone for five minutes, and suddenly it was 1 a.m.” The person is exhausted, yet continues scrolling through upsetting news, frightening predictions or other people’s lives.
Doomscrolling is not simply a lack of discipline. Our brains are naturally drawn towards possible threats because noticing danger has always supported survival. Each alarming headline tells the nervous system that there may be something important it must understand. The next post promises more information and perhaps a sense of control, so we continue scrolling.
For someone already carrying stress or past trauma, uncertainty can feel especially difficult. Scanning for information may become the brain’s way of asking, “Am I safe? Is there something I need to prepare for?” Unfortunately, the answer rarely arrives. Instead, every new story introduces another concern.
Consider someone who goes to bed after a demanding day. Their body is tired, but their mind has had no opportunity to process what happened. They open social media for relief and encounter distressing content. Their heart rate increases, their thoughts become faster and sleep moves further away. The phone may distract them from uncomfortable feelings temporarily, while also keeping their system alert.
Screens can delay sleep by displacing bedtime and exposing us to light, but the emotional content matters too. Anger, fear and comparison create cognitive arousal, the opposite of the slowing down that sleep requires.
Rather than imposing a harsh digital ban, begin with a realistic boundary.
- Choose a time to stop reading news, charge the phone away from the bed or replace the final 20 minutes of scrolling with something less stimulating.
- Dim the lights, stretch gently, listen to familiar music or write down tomorrow’s worries so the brain does not have to keep rehearsing them.
- If you slip, respond with curiosity rather than criticism: “What was I trying not to feel, or hoping to find?”
When doomscrolling repeatedly disrupts sleep or becomes the main way you manage anxiety, therapy can help explore the need beneath the habit. The aim is not merely to take away the phone, but to help the nervous system discover safer ways to settle.
Sometimes, switching off the screen begins with helping the mind believe that it is safe to stop watching.
By Ms Arouba Kabir, Psychologist, Founder Enso wellness
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