Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.

What happens when you consume pain killers?

She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.

While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.

A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.

What can be done?

While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.

Pasricha suggests acetaminophen.

However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.

Why is it a concern?

NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.

A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.

Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".

Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.

An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.

A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.

Your weight not only affects your heart health but also your brain health. A recent study published in the Journal of Clinical Endocrinology & Metabolism has revealed a powerful connection between your body weight, heart and brain.

After studying over 500,000 people, scientists discovered that having a high Body Mass Index (BMI) can nearly double your chances of developing brain-related illnesses later in life, which confirms that being overweight and having high blood pressure are not just general health concerns, they are direct causes of dementia.

How Does Your Weight Affect Brain Health?

The study focused heavily on vascular dementia, a specific type of memory loss that occurs when the brain is damaged because of a lack of blood flow.

Think of your blood vessels like a system of pipes. If those pipes are narrowed or blocked due to weight-related issues, the "engine" (your brain) doesn't get the fuel it needs. Over time, this lack of oxygen and nutrients leads to permanent brain damage and the loss of memory and thinking skills.

Researchers found that high blood pressure, often caused by carrying extra weight, is the main "middleman" in this process. Blood pressure is measured with two numbers, and both play a part in brain health:

Systolic

This is the pressure when your heart beats. It accounts for about 18 percent of the link between obesity and dementia.

Diastolic

This is the pressure when your heart rests between beats. It accounts for about 25 percent of the link. When these numbers stay high, they constantly "batter" the delicate vessels in the brain, causing them to weaken or clog.

How Weight Affects the Brain

Beyond just blood flow, a high BMI impacts the brain in several other ways:

Increased Inflammation

Obesity often causes the body to be in a constant state of "alarm" or inflammation. This can irritate the immune system and eventually damage brain cells.

Metabolism Issues

When the body struggles to process energy and food properly, it changes how the brain uses energy, which can lead to cognitive decline.

Heart Strain

A heart that has to work harder to pump blood through a larger body eventually becomes less efficient at sending blood all the way up to the brain. Your heart essentially has to do twice as much work as it would at a lower weight.

Can Preventing Obesity Help Dementia?

The most encouraging takeaway from this study is that dementia isn't always a matter of bad luck or "old age." Researchers call this an unexploited opportunity.

By managing your weight and blood pressure early in life, through a healthy diet, consistent exercise, and good sleep, you are essentially "dementia-proofing" your brain. The researchers suggested that intervening early, possibly even with weight-loss medications before symptoms start, could be a key strategy for protecting brain health in the future.

How Much Does Obesity Affect Worldwide?

According to the World Health Organization, one in eight people in the world are living with obesity. In 2022, about 2.5 billion adults were overweight. Causes of it vary, from things like diseases or chronic conditions, to the kind of food that is available to consume.

Heart attacks need immediate intervention and Dr. Balbir revealed one medicine that can save a life when this happens: Aspirin. In an interview with HealthandMe, Dr. Singh revealed that one does not need fancy equipment to help a person having a heart attack.

“If the history of the family history or cholesterol or diabetic. This patient is at risk, so what is the medicine if you get such a symptom? Aspirin.”

What Medicine Can Help a Heart Attack?

Dr. Singh points out that if you or someone near you begins to experience symptoms of a heart attack, such as heavy chest pain, pressure, or unexplained sweating, taking a dissolvable aspirin immediately can be a lifesaver.

By dissolving a tablet (like Dispirin) in a glass of water and drinking it, the medicine dissolves into the bloodstream much more quickly than simply ingesting it.

Aspirin works by thinning the blood and preventing further clotting in the arteries, which can stop a heart attack from getting worse before medical professionals arrive.

Other Preventative Measures To Take For Heart Attack

Before medical professionals arrive, performing CPR can also help save a person's life; however, one must know the right way to do CPR.

While speaking to HealthandMe, Dr Singh mentioned a viral video where a person collapses and someone attempts to give them CPR while they are still sitting in a chair, notng that this was 'a dangerous mistake' and people should steer clear away from such false videos.

He explained that you cannot perform CPR on someone who is sitting up as the body must be positioned correctly for the heart and lungs to receive the benefit of the chest compressions.

Without the proper technique, blood will not reach the brain and your efforts will not help the patient. Understanding the proper sequence of events is the difference between a failed attempt and a saved life.

Step 1: The Importance of Positioning

If someone collapses, immediately place them flat on their back on a hard floor. You need the ground's resistance to pump the heart manually. In this position, the heart is "sandwiched" between the rib cage and spine. On a soft bed, your presses will fail to squeeze the heart effectively.

Step 2: Focus on the Heart First

Dr. Singh emphasizes that restarting the heart is the absolute priority. Place both hands in the center of the chest and use your body weight to press firmly. By pushing the rib cage toward the spine, you force the heart to pump. Often, once circulation starts, the patient begins breathing again spontaneously.

Step 3: The Proper CPR Sequence

If the person doesn't wake up, begin a rhythm of three chest presses followed by one mouth-to-mouth breath. Lock your elbows and press hard to ensure the heart is being squeezed between the bones. This specific cycle keeps oxygenated blood moving to the brain, preventing permanent damage during a cardiac emergency.

How Common Are Heart Attacks?

According to the Centers for Disease Control and Prevention, heart attacks claim a life every 34 seconds. In 2023, it caused nearly 920,000 deaths, one in every three recorded. Hence it is important to know not just the ways to help when someone has a heart attack but also how to prevent them.

Heart attacks need immediate intervention, and Dr. Balbir revealed one medicine that can save a life when this is happening: Aspirin. In an interview with HealthandMe, Dr. Balbir Singh revealed that one does not need fancy equipment to help a person having a heart attack.

“If the history of the family history or cholesterol or diabetic. This patient is at risk, so what is the medicine if you get such a symptom? Aspirin.”

What Medicine Can Help a Heart Attack?

Dr. Singh points out that if you or someone near you begins to experience symptoms of a heart attack, such as heavy chest pain, pressure, or unexplained sweating, taking a dissolvable aspirin immediately can be a lifesaver.

By dissolving a tablet (like Dispirin) in a glass of water and drinking it, the medicine enters the bloodstream quickly.

Aspirin works by thinning the blood and preventing further clotting in the arteries, which can stop a heart attack from getting worse before medical professionals arrive.

Other Preventative Measures To Take For Heart Attack

Before medical professionals arrive, doing CPR also helps; however, one must know the right way to do CPR.

There is a lot of misinformation online. Dr. Singh mentions a viral video where a person collapses and someone attempts to give them CPR while they are still sitting in a chair. This is a dangerous mistake.

He explained that you cannot perform CPR on someone who is sitting up. The body must be positioned correctly for the heart and lungs to receive the benefit of the chest compressions. If the technique is wrong, the blood will not reach the brain, and your efforts will not help the patient. Understanding the proper sequence of events is the difference between a failed attempt and a saved life.

Step 1: The Importance of Positioning

If someone collapses, immediately place them flat on their back on a hard floor. You need the ground's resistance to pump the heart manually. In this position, the heart is "sandwiched" between the rib cage and spine. On a soft bed, your presses will fail to squeeze the heart effectively.

Step 2: Focus on the Heart First

Dr. Singh emphasizes that restarting the heart is the absolute priority. Place both hands in the center of the chest and use your body weight to press firmly. By pushing the rib cage toward the spine, you force the heart to pump. Often, once circulation starts, the patient begins breathing again spontaneously.

Step 3: The Proper CPR Sequence

If the person doesn't wake up, begin a rhythm of three chest presses followed by one mouth-to-mouth breath. Lock your elbows and press hard to ensure the heart is being squeezed between the bones. This specific cycle keeps oxygenated blood moving to the brain, preventing permanent damage during a cardiac emergency.

How Common Are Heart Attacks?

According to the Centers for Disease Control and Prevention, heart attacks claim a life every 34 seconds. In 2023, it caused nearly 920,000 deaths, one in every three recorded. Hence it is important to know not just the ways to help when someone has a heart attack but also how to prevent them.