THIS Alternative Could Help Prevent Gut Damage Caused By Painkillers

Updated Dec 26, 2024 | 11:04 AM IST

SummaryPainkillers or NSAIDs are great in treating short term pain, but these painkillers could damage the lining of your gut. So, are there any alternatives? Read on to know more.
THIS Alternative Could Help Prevent Gut Damage Caused By Painkillers

Credits: Canva

Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.

What happens when you consume pain killers?

She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.

While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.

A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.

What can be done?

While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.

Pasricha suggests acetaminophen.

However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.

Why is it a concern?

NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.

A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.

Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".

Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.

An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.

A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.

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World Suicide Prevention Day 2026: Why Women Still Face Mental Health Barriers

Updated Sep 10, 2026 | 07:40 PM IST

SummaryGender roles, unequal distribution of power, financial dependence, even the caregiving responsibilities, safety concerns, all of these are some of the social and cultural factors that affect women's access to mental health care.
World Suicide Prevention Day 2026: Why Women Still Face Mental Health Barriers

Credit: iStock

Awareness about mental health has grown, but access to care remains a challenge. For women, stigma is only one barrier. Social and family responsibilities, financial dependence, caregiving, geographical gaps, and the tendency to dismiss symptoms as “hormonal” can also delay care, said experts on World Suicide Prevention Day 2026.

HealthandMe spoke to mental health experts about why awareness has not translated into equitable access to care.

WHO estimates that 6.9% of adult women globally have depression, compared with 4.6% of adult men — making depression about 1.5 times more common among women.

“Awareness has grown faster than access, but this isn't a gap women are failing to close on their own; it's a reflection of where women are placed in our social and family structures to begin with,” Dr Kavita, Child and Adolescent Psychiatrist, Founding Cohort Member, India Mental Health Alliance and Co-founder, Children First, told HealthandMe.

She said the gaps extend across diagnosis, research, interventions and care pathways. “Currently, care pathways, definitions, interventions and policies do not center women,” she said.

Why Women Delay Mental Healthcare

Dr Mimansa Singh Tanwar, Senior Clinical Psychologist and Head of the Fortis School Mental Health Program, said stigma is compounded by social and cultural barriers.

“Gender roles, unequal distribution of power, financial dependence, even the caregiving responsibilities, safety concerns, all of these are some of the social and cultural factors that affect women's access to mental health care,” she said.

Women may also put family responsibilities ahead of their own health.

“Women still tend to forego care because of the added responsibility that they continue to have when it comes to taking care of family and other responsibilities,” Tanwar told HealthandMe.

Dr Priyanka Mittal, Clinical Psychologist and Lead, IMHA, said financial dependence can limit women's ability to seek care.

“When a woman doesn't control her own finances, seeking help for her mental health isn't a decision she gets to make independently,” she said.

The expert highlighted how women's distress are often minimized.

“She's called ‘sensitive,’ ‘hormonal,’ or ‘going through her problems’ — rather than recognized as someone with a mental health concern worth addressing,” Mittal told HealthandMe.

When Symptoms Are Dismissed As ‘Hormonal’

Pregnancy, postpartum, perimenopause and menopause can involve biological changes that affect mood. But experts caution against treating persistent distress as simply hormonal.

WHO estimates that about 10% of pregnant women and 13% of women who have recently given birth experience a mental disorder, primarily depression.

“While there are biological changes that can affect our mood and can lead to anxiety, depression, irritability, and emotional exhaustion, these biological changes should not be only connoted as being hormonal and phase-like,” Tanwar said.

Dr Jothi Neeraja, Founder, Chairwoman and MD, Maarga MindCare Hospitals, said women's distress is often attributed to life circumstances rather than recognised as a mental health concern.

“During pregnancy, after childbirth and around menopause, symptoms may also be attributed only to hormonal changes,” she said.

Dr Kavita said even well-meaning explanations can delay care.

“A lot of it comes from genuinely well-meaning explanations,” she said. “Mood changes after childbirth are common, so families, and sometimes clinicians, default to ‘it's just hormones’ or ‘every new mother feels this way.’”

“Duration, severity and functional impact matter more than the explanation someone reaches for,” she said.

Rural Women Face Another Care Gap

The experts noted that access to mental health can be even more limited outside urban centers.

“If a woman reaches a medical system at all, it's usually a PHC, and usually for an emergency or childbirth — not for mental health,” Mittal said.

Tele-services such as Tele-MANAS and other free or affordable services have started helping bridge some of the gap, particularly in tier-two and rural areas, she said.

Dr Kavita also pointed to gaps in community-level mental health infrastructure, saying services closer to women may be too limited to provide meaningful care.

Access Is Not Enough

Starting treatment does not guarantee continuity of care. “Even if, let's say, care is started, the continuity with which one is able to maintain that may not be there again because of the multiple responsibilities that they have to bear,” Tanwar said.

Neeraja said mental healthcare must extend beyond helplines. “For women, however, access cannot end with a helpline,” she said.

She called for continuity of care, affordable specialists, screening through reproductive and primary healthcare services, privacy and stronger referral systems.

“Mental healthcare becomes meaningful when seeking help is easy, safe and followed by appropriate care,” she said.

Mittal described treatment as a chain in which every step matters.

“It's a series of events... you need to know it exists, then know where to go, then know the steps that follow. Miss any link, and the cycle of treatment or intervention breaks,” she said.

Building Women-Centered Mental Healthcare

The experts said mental healthcare should be integrated into services women already use.

“It would meet women where they already are, rather than expecting them to seek out psychiatry or therapy separately,” Dr Kavita said.

This could include mental health screening during antenatal and postnatal visits, training obstetricians and gynecologists to identify concerns, and helping primary-care providers recognise warning signs.

Families and partners can also play a role in recognizing changes and encouraging women to seek help.

Awareness, the experts said, must ultimately translate into accessible, affordable and continuous care. “Women-centered care isn't a separate track; it's the standard track for care, done well,” Dr Kavita said...

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Prostate Cancer: What's Fact, What's Fiction

Updated Sep 11, 2026 | 12:00 AM IST

SummaryProstate cancer myths can create unnecessary fear or false reassurance. Understanding real risk factors, symptoms, screening and treatment options helps men make informed healthcare decisions.
Prostate Cancer: What's Fact, What's Fiction

Credit: AI

Prostate cancer remains the fourth most common cancer worldwide and the most frequently diagnosed cancer in men across most nations, with an estimated 1.5 million new cases and nearly 420,000 deaths in 2024 alone.

Despite how common it is, misinformation still shapes how men view their risk, symptoms, and treatment choices. Here's a closer look at some myths that just won't go away, and what the evidence actually says.

1. Myth: A high prostate-specific antigen (PSA) number automatically means cancer.

Fact: PSA can rise for reasons that have nothing to do with cancer, including prostatitis and an enlarged prostate (benign prostatic hyperplasia or BPH). A raised PSA is a cue to investigate further, not a diagnosis in itself.

2. Myth: Prostate cancer always comes with warning symptoms.

Fact: Early-stage disease is usually silent. Most men are picked up through screening or incidental testing, and symptoms like trouble urinating typically show up only once the cancer has advanced.

Also read: Hot Tea, Coffee May Triple Esophageal Cancer Risk: Study

3. Myth: Testosterone therapy fuels prostate cancer.

Fact: This idea comes from decades-old research. More recent studies haven’t found that testosterone replacement therapy meaningfully raises prostate cancer risk in most men, though doctors still monitor patients on it as a precaution.

4. Myth: No family history means you’re in the clear.

Fact: A family history does raise risk, but most men diagnosed have no affected close relative. Age, ethnicity, and lifestyle count just as much.

5. Myth: Treatment always leaves men permanently impotent or incontinent.

Fact: Side effects vary depending on the treatment, the person’s overall health, and the stage of cancer. Many men see real improvement within a year, and not everyone experiences these issues at all.

Also read: 9/11-Linked Cancer Cases Surge 75%: Why Researchers Are Concerned

6. Myth: Only older men need to worry about this.

Fact: Risk does climb with age, especially past 50, but men in their forties can be affected too, particularly with a strong family history or certain genetic mutations.

7. Myth: Getting a vasectomy raises your risk of prostate cancer.

Fact: Decades of research have consistently found no link between vasectomy and prostate cancer risk, despite how persistent this myth has been.

8. Myth: A prostate cancer diagnosis means your days are numbered.

Fact: Prostate cancer has one of the highest survival rates among major cancers when caught early, and many men live for decades after diagnosis. Outcomes depend heavily on the stage and grade at diagnosis, not the diagnosis itself, and many low-risk cases never need aggressive treatment at all.

9. Myth: How often a man ejaculates affects his prostate cancer risk.

Fact: Several large studies have found no such link, and some even suggest higher ejaculation frequency may be tied to slightly lower risk. It isn’t something men need to actively manage.

Created for general disease awareness only. Kindly consult your physician for any further information.

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Why Are Kidney Stones Becoming Harder To Treat? Could Our Modern Diet Be Playing A Role?

Updated Sep 10, 2026 | 10:00 PM IST

SummaryRising kidney stone cases may be linked to modern dietary patterns, including high salt, sugar and animal protein intake, alongside dehydration and other lifestyle factors.
Why Are Kidney Stones Becoming Harder To Treat? Could Our Modern Diet Be Playing A Role?

Credit: AI

Are urologists seeing more difficult or complex kidney stones in recent years? Yes, it’s true. Nowadays the trend for oxalate stones and infective stones are rising

They both are complex in their treatment. Oxalate stones are hard, they are known to grow as per the shape of the internal structure of the kidney and are one of the hardest of all stones, at times, even hard for a laser to break them into fragments. Harder stones may need a second procedure to break them into finer fragments.

Infective stones primarily have infection within them, very common in diabetics and long term infected stones. These stones can fill up the kidney with pus and can be life threatening as well, causing diffuse infection in the blood, called as sepsis. With incidence of diabetes the management of these stones require considerable expertise and caution.

How can dehydration and not drinking enough water increase the risk of kidney stones?

The contemporary understanding of the genesis of kidney stones is the 'solute-solvent' theory. It means than more the amount of crystals (read solute viz oxalate crystals, uric acid crystals etc.) and less the amount of water, concentrated urine, lesser is the solubility of these crystals in the urine. Thus they sediment and cause faster stone formation.

Also read: What Happens When Kidney Function Declines: Understanding The Stages Of Chronic Kidney Disease

Can eating more processed foods, salt and protein than the body needs make kidney stones more likely?

Processed foods are high on oxalates and phosphorus. They act as the primary anion in stone formation. Thus promoting higher amount stone formation and harder stones as well. Also protein in urine helps in stabilising the already aggregated crystals, thus leading to a harder stone. Protein supplements are to be consumed only as per the contemporary need of the body after consulting a dietician

Can more fruits and vegetables and staying well hydrated help prevent kidney stones?

Definitely! Another point i want to make here is that there are some naturally occurring substances in urine which prevent stone formation, viz citrate. Higher the citrate levels in urine, lesser are the chances of stone formation. Thus it is advisable to have more citrate in diet (citrus fruits). For patients with recurrent stone formation in kidney, it is advisable to use citrate supplements. Another factor is blood uric acid levels.

Uric acid crystals can independently form a stone and it can deposit itself on already formed stone, making it later and more complex to treat. Uric acid is majorly found in animal based diet. There are other factors which may reduce the stone formation, however till date only proven thing to prevent stone is abundant citrate and good amount of water intake. All fruits have variable amount of citrate however citrus fruits have the most.

By Dr. Sony Mehta, Consultant Urologist, Saifee Hospital, Mumbai

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