Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.

What happens when you consume pain killers?

She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.

While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.

A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.

What can be done?

While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.

Pasricha suggests acetaminophen.

However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.

Why is it a concern?

NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.

A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.

Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".

Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.

An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.

A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.

Did you know? Discontinuing activities and overly restrictive behaviour, including unnecessary bed rest, does not improve implantation chances when it comes to IVF. Instead, balanced living, moderate activity, proper nutrition, and emotional well-being are important after the procedure. Hence, make sure to follow the advice given by a fertility consultant. Women should prioritise their health.

A failed IVF attempt is not just a financial crisis but also an emotional rollercoaster. For several couples struggling with infertility, IVF offers a ray of hope and may even help them conceive a baby. However, sometimes the attempt can fail due to several reasons, but do not let that affect your motivation to engage in your favourite activities.

Dr Rashmi Agarwal, Fertility Specialist, Nova IVF Fertility, Gurugram, in an interview with Health and Me, spoke about the rising incidence of infertility in young couples, and how following a restricted behaviour may only lower the odds of conceiving a baby.

How is IVF coming to the rescue of young couples?

Infertility cases are rising among couples. There are a large number of couples who struggle with infertility and opt for in vitro fertilisation (IVF). However, couples tend to have doubts regarding it. For those who undergo IVF, the period after embryo transfer is filled with hope, anxiety, and a strong urge to “do everything right”. Many women feel that after the procedure, complete bed rest, taking it easy, and avoiding any activity can increase the chances of pregnancy. However, maintaining a balanced routine is often more beneficial than extreme rest.

What happens after an embryo transfer

After embryo transfer, many patients assume that movement could disturb implantation, and they suddenly avoid all activities without asking the doctor. They try not to walk, work, or do any household chores. But do not worry or panic, as the embryo is safely placed inside the uterus and cannot “fall out” with normal movement. The body is naturally designed to support implantation. There is no evidence available that claims that strict bed rest improves success rates. However, staying inactive for long periods can lead to stiffness, poor blood circulation, and increased stress or anxiety, which can take a toll on overall well-being.

How to improve chances of IVF success

Light activities like walking, gentle stretching, and routine household tasks are generally safe, as recommended by the doctor. Eating a nutritious diet, staying hydrated by drinking 3–4 litres of water per day, de-stressing by doing meditation or reading, and getting enough sleep can be beneficial for women. Many women can also overthink, become anxious, and constantly worry about pregnancy. Hence, opting for relaxing activities like deep breathing, meditation, reading, staying connected with loved ones, and maintaining a positive mindset can help patients cope better during the waiting period, although it is not advised to overexert or do any strenuous activities without the doctor’s knowledge.

Following the expert’s instructions without fail, staying active, doing light exercises, and paying attention to physical and emotional well-being can support a smoother IVF journey.

Delhi-NCR witnessed unexpected showers in the city this year in the month of April. Before the heatwave could get as severe as it usually is every season, there were a few days where the national capital witnessed refreshing showers—but as it turns out, these showers often increase the risk of diseases like malaria. Yes, unexpected showers may bring temporary relief from heat, but they also quietly reset the risk for diseases like malaria. The concern today is not just rainfall, but how changing climate patterns are shifting the timeline of disease transmission—often weeks before the monsoon fully arrives.

Ahead of World Malaria Day, Dr Suranjit Chatterjee, Senior Consultant-Internal Medicine, Indraprastha Apollo Hospital, Delhi, spoke about the effects of such unexpected rains ahead of the monsoon season.

Has the malaria pattern changed?

Malaria has long been seen as a monsoon-linked illness, but that pattern is changing. Intermittent rainfall, rising temperatures, and increased humidity are now creating ideal breeding conditions much earlier in the year. Even a short spell of rain can lead to water accumulation in urban areas—on terraces, construction sites, in clogged drains, and in poorly managed storage spaces. These become hidden breeding grounds for mosquitoes, accelerating their life cycle and increasing the risk of early transmission.

When should you get tested for malaria?

From a healthcare perspective, this shift is significant. The first fever after early showers is often overlooked or dismissed as a seasonal viral infection. However, malaria in its early stage can closely resemble common viral illnesses, presenting with symptoms such as fever, chills, headache, body ache, and fatigue. This overlap frequently delays diagnosis. Any fever that persists beyond 2–3 days, recurs, or does not respond to basic treatment should be tested promptly. Early detection remains critical to preventing complications.

What are the symptoms of malaria?

Early malaria can look like a common viral fever. The symptoms of the disease are:

1. Body aches
2. Fever
3. Chills
4. Weakness
5. Headaches

Malaria prevention matters

Waiting for the monsoon to begin preventive action is no longer effective. The response must start with the first signs of rain. Clearing drains, eliminating stagnant water, monitoring construction zones, and ensuring proper waste management are essential early steps. At the household level, covering water containers, maintaining clean terraces, and regular checks for water accumulation can significantly reduce risk. Some of the key precautions to take against malaria are the following:

1. Use a mosquito repellent before going outdoors
2. Wear long sleeves and light coloured clothes
3. Use bed nets
4. Avoid keeping the windows open, especially in the evening
5. Standing water are breeding ground for malaria; avoid water sit in coolers or pots for too long

A year-round public health priority

World Malaria Day serves as a reminder that malaria prevention is not seasonal—it is continuous. In an era of unpredictable weather patterns, cities and communities must adapt quickly. Acting only when cases begin to rise means reacting too late. The real shift lies in recognising that prevention must begin with the first unexpected shower, not the peak of the monsoon.

Urgent action is required to strengthen diagnostics and vaccines to address gaps in dengue treatment, public health experts said.

The experts, including scientists and policymakers, were speaking at a day-long dialogue hosted in New Delhi by the Drugs for Neglected Diseases initiative (DNDi) in collaboration with the Translational Health Science and Technology Institute (THSTI), the Ministry of Health and Family Welfare, and the WHO South-East Asia Region.

The convening assumes significance ahead of the monsoon season, which historically sees a rise in Aedes aegypti mosquito populations and dengue transmission across health systems in South and South-East Asia.

"The WHO South-East Asia Region alone accounts for more than half of the global dengue burden, with 1.3 billion people living at risk across 10 endemic countries," said Dr Catharina Boehme, Officer in charge, World Health Organization, South-East Asia Regional Office.

Dr. Boehme called the rising burden of dengue both an economic crisis and a social crisis. She noted that beyond health system costs, dengue often leads to "lost productivity, lost wages, lost futures".

"To change this trajectory, we must close the gap on diagnostics, on vaccines, on therapeutics, and on health system resilience," Dr. Boehme said.

Also read: New dengue vaccine over 80% effective, prevents severe disease for up to 5 years

India Advancing in Dengue Fight, Gaps Remain

India reported over 2.89 lakh dengue cases in 2023, though experts believe the actual burden could be significantly higher due to underreporting and surveillance gaps.

Taruna Madan Gupta, Scientist G and Head, Development Research Division, ICMR, called dengue an "unequivocally a national health priority for India."

Gupta noted that "India is advancing on multiple fronts—from strengthening public health systems to enabling public-private partnerships, including Phase III trials of an indigenous tetravalent dengue vaccine with over 10,000 participants, and regulatory progress on global vaccines".

However, the expert flagged a critical gap, which is "the absence of an effective therapeutic" for the mosquito-borne disease.

The experts noted that even though there are improvements in surveillance and scientific understanding, patients still lack access to specific treatment options.

“Addressing this gap requires sustained commitment from governments, funders, and partners," said Dr Sanjay Sarin, Continental Lead Asia and Director South Asia, DNDi.

What Is Dengue?

Dengue fever is a viral disease transmitted by Aedes mosquitoes, which are most active during the daytime. Dengue fever typically has minor or no symptoms, but it can occasionally result in severe sickness, hospitalization, and even death.

Common Symptoms include:

• Sudden onset of high-grade fever.
• Intense headache
• Severe muscle, joint, or bone pain.
• Skin Rash that often appears 2–5 days after the fever starts
• Nausea and Vomiting
• Fatigue

It estimates that:

• About 390 million dengue infections occur annually worldwide
• Nearly 100 million people develop symptoms each year

These vaccines are designed to protect against all four serotypes of the virus, with a focus on reducing severe disease and hospitalizations.