THIS Alternative Could Help Prevent Gut Damage Caused By Painkillers

Updated Dec 26, 2024 | 11:04 AM IST

SummaryPainkillers or NSAIDs are great in treating short term pain, but these painkillers could damage the lining of your gut. So, are there any alternatives? Read on to know more.
THIS Alternative Could Help Prevent Gut Damage Caused By Painkillers

Credits: Canva

Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.

What happens when you consume pain killers?

She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.

While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.

A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.

What can be done?

While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.

Pasricha suggests acetaminophen.

However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.

Why is it a concern?

NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.

A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.

Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".

Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.

An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.

A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.

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Challenge Your Brain To Keep It Young: New Study Says Learning Another Language Can Help

Updated Jul 8, 2026 | 08:00 AM IST

SummaryA new study says learning new languages requires attention, memory, problem-solving and cognitive control, all of which help in keeping the brain younger.
Learning Another Language May Help Slow Brain Ageing

Credit: AI

Learning a second or even a third language may do more than expand your communication skills. According to a new study presented at the Federation of European Neuroscience Societies (FENS) Forum 2026 in Barcelona, learning a new language could also help keep your brain younger as you age.

The findings of the study say that people who speak multiple languages have brains that appear biologically younger than those who speak only one language. The research added to the growing evidence that multilingualism has a beneficial effect on healthy cognitive ageing.

About The Study

To investigate how language affects the ageing brain, researchers analysed brain activity in adults living in Spain's multilingual Basque region.

They used magnetoencephalography (MEG), a non-invasive brain imaging technique that records the brain's electrical activity, along with artificial intelligence (AI) to ascertain each participant's brain age.

Rather than relying on a person's actual age, the AI model assessed how well different regions of the brain communicated with one another, a key marker that normally weakens with age.

Researchers first trained the AI using brain scans from 728 adults with varying language abilities before validating the findings in an independent group of 144 participants.

Read more: Normal Ageing or Alzheimer's? Doctors Explain Six Key Differences to Watch For

The results revealed an association between multilingualism and a younger-looking brain. Compared with people who spoke only one language, bilingual participants had brains that appeared around six years younger. Those who spoke three languages had brains that looked approximately seven years younger, while participants fluent in four languages had brains that appeared up to 13 years younger.

Researcher Lucia Amoruso, deputy scientific director at the Basque Center on Cognition, Brain and Language in San Sebastián, Spain, said, “In simple terms, people who spoke more languages tended to have brains that looked younger than expected for their chronological age.”

The researchers also found that language proficiency mattered. People who learned additional languages earlier in life and became more fluent showed even greater differences in brain age.

Is Multilingualism The Key To Keep Your Brain Younger?

Scientists believe speaking multiple languages provides the brain with a constant mental workout. Regularly switching between languages requires attention, memory, problem-solving and cognitive control, all of which strengthen the neural networks involved in thinking and decision-making.

This exercise may help maintain stronger communication between brain regions, increasing the brain's resilience against age-related decline.

While the team considered factors like age, sex, and education, multilingual individuals may also be more likely to engage in other habits that are beneficial for the brain.

Although the findings are encouraging, the researchers say that the study does not prove that learning another language directly slows brain ageing or prevents dementia. Experts say further long-term studies are needed to determine whether multilingualism can reduce the risk of neurodegenerative diseases such as Alzheimer's disease.

Despite the need for more research, scientists say the findings offer another compelling reason to learn a new language. Whether through formal classes, language-learning apps or everyday conversations, developing language skills could provide meaningful mental stimulation throughout life.

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The New Chapter After Cancer: Focusing On Wellness And Quality Of Life

Updated Jul 8, 2026 | 10:00 AM IST

SummaryThe goal is no longer to eliminate cancer cells, but to create a life that feels fulfilling and meaningful. Survivors are encouraged to focus on three things treatment itself cannot provide: strength, joy, and a renewed sense of control.
The New Chapter After Cancer: Focusing On Wellness And Quality Of Life

Credit: iStock

Completing cancer treatment is often imagined as the moment life returns to normal. The final chemotherapy session ends, follow-up scans show encouraging results, and the long-awaited words, “You’re in remission,” bring immense relief. Family and friends celebrate the milestone, expecting life to pick up where it left off.

Yet for many survivors, the end of treatment marks the beginning of a different journey. The hospital visits may become less frequent, but new questions often take their place. Will energy levels ever return? Is it normal to still feel anxious before every check-up? How does one rebuild a life that has been profoundly changed by illness?

Life After Cancer

Life after cancer is not simply about surviving; it is about learning to live well again. This phase is an opportunity to focus not only on physical recovery but also on emotional healing, meaningful relationships, and rediscovering a sense of purpose. Survivorship is not defined by the absence of disease alone; it is measured by the quality of life that follows.

During treatment, every decision revolves around cancer. Appointments, medications, scans, and side effects dominate daily life. Once treatment ends, the focus gradually shifts from fighting the disease to rebuilding health and well-being. This transition, often referred to as survivorship care, is about moving from crisis management to long-term wellness.

The goal is no longer simply to eliminate cancer cells, but to create a life that feels fulfilling and meaningful. Survivors are encouraged to focus on three things treatment itself cannot provide: strength, joy, and a renewed sense of control.

Quality of life after cancer extends far beyond follow-up scans and medical reports. It encompasses physical, emotional, social, and practical well-being. Paying attention to each of these areas can help survivors thrive rather than merely cope.

Physical Recovery After Cancer Treatment

Physically, the body often needs time to recover from the effects of chemotherapy, surgery, radiation, or hormone therapy. Fatigue, reduced stamina, neuropathy, weight changes, and muscle loss are common challenges. Regular movement plays a critical role in recovery.

Experts recommend at least 150 minutes of moderate exercise each week, along with two sessions of strength training to rebuild muscle and improve energy levels. For survivors experiencing lymphedema, pelvic floor concerns, or mobility limitations, working with a physiotherapist can provide targeted support. A balanced diet rich in protein also helps restore strength and independence.

Emotional Recovery Post Cancer Treatment

Emotional recovery deserves equal attention. Fear of recurrence, anxiety before follow-up scans, survivor's guilt, and grief for the life that existed before diagnosis are all common experiences.

These feelings are not symptoms of weakness; they are natural responses to a life-changing event. Seeking support from a psycho-oncologist, counsellor, or support group can significantly improve emotional well-being. Even simple practices such as mindfulness, journaling, or spending a few quiet minutes each day focusing on the present moment can help reduce stress and build resilience.

Cancer's Impact On Relationships And Financial Pressures

Cancer can also reshape relationships. Some friendships may change, while family members and partners may continue adjusting to roles they adopted during treatment.

Open conversations about needs, limitations, and expectations can help strengthen these relationships. Reconnecting with supportive people, participating in survivor communities, or mentoring newly diagnosed patients can create a sense of belonging and purpose. Healing is often easier when it happens in the company of others.

Practical concerns can persist long after treatment ends. Financial pressures, career interruptions, insurance challenges, and concerns about returning to work can affect overall well-being. Seeking guidance from social workers, financial counsellors, or patient support organizations can help survivors navigate these issues. In India, government initiatives such as Ayushman Bharat, state-level healthcare schemes, and various non-governmental organizations may offer valuable assistance.

Challenges Of Survivors

One of the greatest challenges survivors face is the expectation of returning to the person they were before cancer. However, recovery is not about going back; it is about moving forward. A new normal often emerges, the one shaped by deeper self-awareness, healthier boundaries, and a greater appreciation for everyday moments.

Many long-term survivors describe experiencing what experts call post-traumatic growth. They report stronger relationships, clearer priorities, and a renewed sense of purpose. They become more intentional about how they spend their time and energy, recognizing that health and meaningful experiences deserve as much attention as professional achievements.

The first year after treatment is a time of adjustment. Establishing healthy routines, gradually resuming work and hobbies, staying consistent with follow-up appointments, and setting goals unrelated to cancer can help restore confidence. Whether it is taking a short trip, learning a new skill, planting a garden, or simply enjoying time with loved ones, these experiences remind survivors that life extends beyond medical milestones.

Risk of New Symptoms

At the same time, wellness does not mean ignoring new symptoms. Persistent pain, unexplained weight loss, unusual bleeding, ongoing fatigue, or symptoms of anxiety and depression that last more than two weeks should be discussed with a healthcare provider. Survivorship care is an essential part of recovery, and seeking help when needed is a sign of self-care, not concern.

Cancer may have changed the course of life, but it does not define its future. The chapter after treatment may look different from the one that came before, but it can still be rich with meaning, connection, and hope.

The treatment phase was about fighting to survive. The next phase is about discovering what makes life meaningful again. It is about protecting quality of life with the same determination that carried survivors through treatment—because surviving cancer is not only about living longer, but about living well.

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Are You Getting The Right Cholesterol Test? ApoB May Be Better Than LDL

Updated Jul 8, 2026 | 02:00 AM IST

SummaryWhile the LDL cholesterol test typically measures the amount of LDL cholesterol in the blood, the ApoB test measures the number of cholesterol-carrying particles—including LDL and other potentially harmful particles—that can enter artery walls and contribute to plaque buildup.
Are You Getting The Right Cholesterol Test? ApoB May Be Better Than LDL

Credit: AI generated image

Millions of people around the world undergo blood tests every year to measure LDL, commonly known as "bad" cholesterol. But researchers now suggest that this standard test may not always provide the most accurate picture of heart disease risk.

A new study from Northwestern Medicine found that a blood test measuring apolipoprotein B (ApoB) may be better than LDL cholesterol testing for identifying people who need more intensive treatment to reduce their risk of heart attacks and strokes.

The researchers also found that using ApoB to guide treatment decisions could prevent more cardiovascular events while remaining cost-effective for healthcare systems. The findings were published in the journal JAMA.

"We found that ApoB testing to intensify cholesterol-lowering medication would prevent more heart attacks and strokes than current practice, and that these health benefits were achieved at a cost that represents good value for US healthcare payers," said study lead author Ciaran Kohli-Lynch, Assistant Professor of Preventive Medicine in the Division of Epidemiology at Northwestern University Feinberg School of Medicine.

ApoB vs LDL: What's the Difference?

Also read: Confused By Your Cholesterol Report? Here's What LDL And ApoB Really Mean

Doctors have traditionally relied on LDL ("bad") cholesterol and non-HDL cholesterol levels to assess heart disease risk and decide when patients should begin or intensify cholesterol-lowering treatment. While these tests provide useful information, researchers say they do not tell the whole story.

The difference lies in what the two tests measure:

  • LDL cholesterol test: Measures the amount of LDL cholesterol in the blood.
  • ApoB test: Measures the number of cholesterol-carrying particles—including LDL and other potentially harmful particles—that can enter artery walls and contribute to plaque buildup.

"Research strongly shows that apolipoprotein B (ApoB) is better at identifying who is at risk because it counts the total number of harmful particles in the blood," Kohli-Lynch said.

According to the researchers, the number of harmful particles may provide a more accurate measure of cardiovascular risk than LDL cholesterol levels alone.

What Is ApoB?

Read More: US Cardiologist Explains Why 2026 AHA Cholesterol Guidelines Recommend Starting Young

In a post on X, Dr. Sudhir, Senior Consultant Neurologist at the Institute of Neurosciences, Apollo Hospitals, Hyderabad, explained that ApoB is a protein found on potentially harmful cholesterol-carrying particles such as LDL and VLDL (very low-density lipoprotein).

"Think of ApoB as a count of the particles capable of entering artery walls and causing plaque. One ApoB is equal to one potentially harmful particle," he said.

Dr. Sudhir explained that two people can have the same LDL cholesterol level but very different numbers of cholesterol-carrying particles. The person with more particles will usually have a higher ApoB level and, potentially, a greater risk of cardiovascular disease.

He added that ApoB often provides a more accurate assessment of heart disease risk than LDL cholesterol alone.

Despite growing evidence supporting ApoB, the test is still not widely used in routine clinical practice because it generally requires an additional blood test beyond the standard cholesterol panel, increasing both cost and inconvenience.

"Our study asked: Is it worth spending extra money to use ApoB instead of LDL to guide treatment intensification?" Kohli-Lynch said.

Dr. Sudhir suggested that ApoB testing should be considered for:

  • people with diabetes,
  • prediabetes,
  • metabolic syndrome,
  • obesity,
  • elevated triglycerides,
  • strong family history of heart disease.

New Cholesterol Guidelines

Earlier this year, the American Heart Association and 10 other medical organisations released updated guidelines recommending that many people begin cholesterol-lowering therapy at younger ages.

"This means it is increasingly important to accurately identify who would benefit most from intensive treatment," Kohli-Lynch said.

The updated guidelines also recommend measuring ApoB, particularly in people with high triglycerides, diabetes or in situations where LDL cholesterol levels may underestimate the number of harmful cholesterol-carrying particles.

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