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Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.
She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.
While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.
A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.
While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.
Pasricha suggests acetaminophen.
However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.
NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.
A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.
Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".
Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.
An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.
A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.
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Students gaming more than 10 hours a week can have long-lasting negative effects on their physical and mental health, a new Australian study suggests.
Researchers from Curtin University, Perth have found that playing online games for over 10 hours can worsen diets, increase body weight and led to poorer sleep than lighter gamers.
Professor Mario Siervo, Curtin School of Population Health said of the results: "What stood out was students gaming up to 10 hours a week all looked very similar in terms of diet, sleep and body weight. The real differences emerged in those gaming more than 10 hours a week, who showed clear divergence from the rest of the sample."
Researchers surveyed 317 students across five Australian universities, with a median age of 20, to understand how time spent gaming each week might affect their diet, sleep, and body composition.
Students were categorized as low gamers (zero to five hours a week), moderate gamers (five to 10 hours) or high gamers, who played video games for more than 10 hours each week.
They found that low and moderate gamers showed largely comparable health outcomes but health indicators deteriorated sharply among students whose gaming time exceeded 10 hours a week.
The study found diet quality declined and obesity was more common once gaming exceeded 10 hours a week, with each extra hour linked to poorer diets even after accounting for other lifestyle factors. While high gamers recorded a body mass index (BMI) of 26.3kg/m2, low and moderate gamers fell within a healthier range, with median BMIs of 22.2kg/m2 and 22.8kg/m2 respectively.
Professor Siervo said: "Each additional hour of gaming per week was linked to a decline in diet quality, even after accounting for stress, physical activity and other lifestyle factors."
Additionally, sleep quality was generally poor across all groups but students who played video games for moderate or high amounts of time reported worse sleep than low gamers.
Despite clear results, the expert added that the study does not prove cause and effect but shows excessive gaming is linked to higher health risks, while low to moderate play appears largely fine.
"Our data suggests low and moderate gaming is generally fine, but excessive gaming may crowd out healthy habits such as eating a balanced diet, sleeping properly and staying active.
"Because university habits often follow people into adulthood, healthier routines such as taking breaks from gaming, avoiding playing games late at night and choosing healthier snacks may help improve their overall well-being," Professor Siervo said.
Playing video games for excessive amount of time has also been linked to paving the way for mental health problems such as anxiety, depression, aggression and poor emotional control as well as social/life problems including neglecting responsibilities, isolation, poor relationships, academic/career impact.
Moreover, previous research has also found that playing games for over three hours straight significantly raises the risk of physical issues. Sessions exceeding this time frame can lead to eye fatigue, headaches, neck pain and wrist pain, regardless of the player's age or gender.
This study was published in Nutrition on January 16.
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Days after eagle-eyed fans spotted Nick Jonas stepping out of the Golden Globes during the Nikki Glaser-hosted show in Los Angeles, the popstar has now revealed what led to him there.
In an X video from January 11, Jonas was seen standing alone outside of a tent at the Beverly Hilton hotel surrounded by palm trees and green foliage, looking like he was taking a breather while sipping from a glass bottle of water and rubbing his chin.
As the clip began to go viral online, users shared their guess on why he had to exit the ceremony, commenting, "Social anxiety got the best of him." Soon after, he did reveal that he anxiety had "hit him like a gut punch" on X.
Living with Type 1 diabetes, Jonas has previously spoken about the emotional challenges of managing a chronic condition and how it has affected his life.
As explained by Dr Sanil Sinhasan, Consultant Psychiatrist at Mind Care Clinic and SRV Hospital, Mumbai, to Health Shots: "Social anxiety disorder is an intense fear of being judged, rejected, or embarrassed in social or performance situations.
"People with social anxiety often worry excessively about how they look, speak or are perceived by others."
This kind of anxiety is typically triggered by meeting new people, public speaking or even everyday interactions like eating in public, stemming from fears of negative evaluation by others.
Symptoms include blushing, sweating, trembling, rapid heartbeat, nausea, dizziness, trouble speaking, stomach issues. If left untreated, social anxiety can become debilitating as it can also cause fast, shallow breathing, muscle tension, suffocation, symptoms that can intensify anxiety further and lead to serious medical events.
Professional therapies such as Cognitive Behavioral Therapy (CBT) and medication such as antidepressants (SSRIs/SNRIs) can offer deeper solutions for managing fear and building skills.
Regular physical activity can also help release endorphins and reduce tension as well avoiding excess caffeine can support mental health.
Mental health experts also recommend opening up to loved ones and avoiding isolation. Speaking to loved ones and sharing how you’re feeling can help ensure your current state doesn’t aggravate.
Doctors also advise speaking therapist if social anxiety significantly impacts your life as professional help is crucial for lasting change.
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Wondering if abnormal bleeding, pelvic pain and leg swelling are signs of something fatal?
According to Dr Ninad Katdare, Consultant Surgical Oncologist, Jaslok Hospital & Research Centre, they may be symptoms of cervical cancer. While many may expect drastic signs such as severe pain, heavy bleeding or obvious illness, identifying certain symptoms can help with early diagnosis and treatment.
Cervical cancer develops in a women's cervix (uterus opening) due to abnormal cell growth, primarily caused by persistent HPV infection, a common infection that's passed through sexual contact.
When exposed to HPV, the body's immune system typically prevents the virus from causing damage however, in a small percentage of people, the virus can survive for years and pave the way for some cervical cells to become cancerous.
Treatment involves surgery, radiation, and chemotherapy, with early detection significantly improving outcomes, though it remains a major cancer in low-income countries. Cervical cancer can also be prevented through vaccination and regular screening (Pap/HPV tests).
Dr Katdare told News18: "In its early stages, it is often more of a whisper than a shout. As a cancer surgeon who has treated hundreds of women with gynaecological cancers, I can say with confidence that recognising these subtle cues can lead to earlier diagnosis and significantly better outcomes."
He recommends looking out for these early signs:
But Dr Katdare warns that any sudden or abnormal changes in discharge may be a symptom of the cancer. “Because discharge issues are commonly linked to infections, many women self-medicate or delay seeking care," he said. “While infections are far more common, chronic or unusual discharge especially in older women requires thorough evaluation."
Discharge may become persistent, watery, foul-smelling, or tinged with blood or pink, brown, or rust-colored if you're suffering from this kind of cancer.
Consistent pelvic pain particularly that occurs outside the menstrual cycle or during sexual intercourse should be a point of concern. According to Dr Katdare, "Pain during intercourse, or dyspareunia, is especially important. It should not be dismissed as ‘just dryness’ or an age-related change. In cervical cancer, this pain may result from inflammation or tumour growth involving the cervix and surrounding tissues."
“These symptoms are often evaluated in isolation because they don’t seem related to the cervix," said Dr Katdare, “which can delay the correct diagnosis."
Ultimately the expert advised: "“Cervical cancer does not always announce itself loudly,. Sometimes, it leaves silent clues. The sooner you listen to them, the better the outcome. If something feels ‘off,’ trust that instinct and seek medical advice. Early action can make the difference between a curable disease and a life-altering diagnosis."
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