Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.

What happens when you consume pain killers?

She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.

While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.

A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.

What can be done?

While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.

Pasricha suggests acetaminophen.

However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.

Why is it a concern?

NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.

A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.

Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".

Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.

An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.

A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.

World Parkinson’s Day is observed every year on April 11 to raise awareness about the progressive, neurodegenerative movement disorder caused by the loss of dopamine-producing brain cells.

People suffering from Parkinson’s face problems in motor movement, tremors, stiffness, and impaired balance. As symptoms progress, people may have difficulty walking, talking, or completing other simple tasks.

The condition primarily affects people over 60, but is now increasingly being seen in young adults. Apart from motor loss, the disease also causes cognitive decline, depression, anxiety, and swallowing problems.

World Parkinson's Day 2026: Origin

Parkinson's Day is observed on the day that marks the birthday of James Parkinson (born in 1755). The London-based doctor was the first to describe Parkinson as a medical condition in 1817, in his famous ‘Essay on the Shaking Palsy’. In 1997, the day was officially established by the European Parkinson’s Disease Association.

World Parkinson's Day 2026: Theme

The theme of World Parkinson's Day 2026 is "Bridge the Care Gap." It reflects a critical challenge that persists despite advances in medical research: many people living with Parkinson's still lack consistent access to specialist care, affordable treatment, and integrated support systems.

The day also aims to raise awareness about neurodegenerative diseases by educating the public about Parkinson's symptoms, causes, and available care.

Global Burden of Parkinson’s

Parkinson's disease affected 11.9 million people in 2021 and will affect 25.2 million people globally by 2050, representing an alarming 112 per cent rise.

According to a 2025 study released by The BMJ, this rise is mainly due to population aging and hence ranks as one of the most rapidly growing neurological disorders based on prevalence and disability. This alarming increase necessitates immediate global health interventions, research innovation, and policy reform to counteract its effects on people and health systems globally.

In addition, lifestyle differences, genetic susceptibility, and environmental exposures can also lead to regional variation in prevalence.

What Happens To Your Brain In Parkinson's Disease?

Parkinson's Disease affects various brain regions, but the primary symptoms arise from the degeneration of neurons in the substantia nigra, a region near the brain's base. This area is crucial for producing dopamine, a chemical messenger essential for smooth and purposeful movement. Research indicates that by the time Parkinson's symptoms become evident, patients have typically lost 60 to 80% or more of these dopamine-producing neurons.

Additionally, individuals with Parkinson’s disease experience a reduction in nerve endings that produce norepinephrine, a neurotransmitter responsible for regulating many involuntary bodily functions, such as heart rate and blood pressure. This loss may account for some non-movement-related symptoms of Parkinson’s, such as fatigue and fluctuations in blood pressure.

How to Prevent Parkinson's

Though there is no cure for Parkinson's disease yet, studies indicate that some lifestyle elements have the potential to shape its incidence and progression.

• Physical Activity – Engaging in regular exercise has been linked to a reduced risk of Parkinson’s, potentially due to its neuroprotective effects.
• Diet and Nutrition – A balanced diet rich in antioxidants, omega-3 fatty acids, and plant-based nutrients may support brain health.
• Environmental Factors – Exposure to pesticides, heavy metals, and air pollution has been associated with an increased risk, suggesting a need for improved public health measures.

Indian Actress Dipika Kakkar, battling liver cancer, underwent another surgery last month for a 1.3 cm cyst that reappeared.

Best known for her role as Simar Bhardwaj in the hit TV show Sasural Simar Ka, Dipika underwent a major tumour-removal surgery in June 2025. She also undertook chemotherapy

In her latest vlog, Dipika shared that the unexpected recurrence has left her feeling anxious and overwhelmed as doctors evaluate the next course of treatment.

"The recurrence that happened with the 1.3 cm cyst has shaken me. I am a little scared now that it shouldn't happen again. I have started dieting, but I feel anxious," she said.

HealthandMe spoke to health experts to understand why cysts recur in liver cancer patients and how it's important to keep monitoring them.

According to health experts, a biannual liver scan is imperative, and it can detect signs of cysts.

“Simple cysts less than 2-3 Cm can be observed with repeat scans every 6 months to 1 year. Suspicious or malignant cysts need surgical resection and oncological treatment based on the histopathology and patient condition,” Dr Manjunath NML, Sr Consultant, Surgical Oncology and Robotic Surgeon, HCG Cancer Hospital, K R Road, Bengaluru.

What Are Liver Cysts? How It's Linked To Cancer

Liver cysts are like bags that are filled with fluid. They are usually not cancer. Most people who have liver cysts do not get cancer.

However, just because one has a cyst, it does not mean it's cancer.

“Cysts in the liver are typically harmless and unrelated to liver cancer. However, unusual types of cysts may suggest malignant changes that need further examination, particularly among risk groups,” Dr. Govind Nandakumar, Consultant – Gastrointestinal Surgery, Manipal Hospitals Hebbal, told HealthandMe.

The experts noted that cases of recurring cysts related to liver cancer are uncommon. But they occur because of

• the presence of cancerous cells,
• regrowth of the organ,
• chronic conditions like cirrhosis.

Also read: 1 In 4 Diabetic Patients in India Suffer from Liver Fibrosis, Finds Lancet Study

Are There Early Warning Signs Patients Should Watch For?

Many liver cysts do not cause any problems in the early stages. That is why regular check-ups with a doctor are important. If a cyst grows or becomes problematic, symptoms may begin to appear. These can include

• abdominal pain,
• bloating,
• nausea,
• weight loss,
• yellowing of the skin,
• fatigue.

Is Recurrent Cysts A Cause Of Worry?

Recurrent cysts can be effectively managed and treated over time. The recurrence does not necessarily imply the progression of the condition itself; however, more tests may be required to determine whether cysts are malignant or benign.

“Cysts with thick walls, septations inside, and solid components in them are more likely to be cancerous. If the cysts are large, they cause symptoms like pain, distension, and obstruction of the bowel or biliary tract,” Dr Manjunath said.

The experts explained that diagnosis can be achieved by scans like ultrasonography, Computerized Tomography CT or Magnetic Resonance Imaging (MRI). Suspicious cysts must be checked via biopsy to confirm malignancy.

While suspicious or malignant cysts require surgical resection and oncological treatment, symptomatic cysts, even if benign, may also require removal.

However, if a liver cyst is detected without suspicious features and is asymptomatic, it usually does not require any intervention, Dr. Manjunath noted.

What if the body whispers long before it screams? For many living with Parkinson’s disease, the earliest signs are not the tremors, but quieter changes, such as a diminished sense of smell, disrupted sleep, or gut problems. The challenge is that we are conditioned to look for the disease only once it becomes visible.

Parkinson’s disease, commonly referred to as a movement disorder, progresses slowly due to the destruction of the nerve cells in the brain.

To understand Parkinson’s disease, think of the brain as a command center where certain nerve cells produce dopamine, a chemical messenger that helps coordinate smooth movement. As these dopamine-producing cells gradually deteriorate, the brain’s signalling system gets disturbed, leading to slower movements, mistaken for normal ageing.

The majority of patients experience subtle early signs much before diagnosis, including a reduced sense of smell, sleep disturbances like insomnia, and persistent digestive problems like constipation. In these cases, timely intervention can reduce movement disability by roughly 40 percent.

Parkinson’s Treatment

Also read: Blame This Brain Region Behind Laughing, Coughing For Your Hypertension

Conventional treatment focuses on medications that boost dopamine levels, but over time, their effectiveness may decline. When drugs are no longer sufficient, doctors may recommend Deep Brain Stimulation (DBS), a surgical approach that works like a pacemaker for the brain and uses chest-connected electrodes to reset faulty signals causing stiffness and tremors.

Unlike fixed traditional stimulation, the advanced Adaptive DBS (aDBS) listens to brain signals in real-time to adjust therapy automatically. Its single threshold mode reacts instantly, boosting stimulation the moment brain signals hit a specific limit and turns it off just as fast once they improve.

Alternatively, its double threshold mode keeps stimulation steady within the safe zone," making only gradual tweaks if signals cross upper or lower limits. This smart system mimics the body’s natural rhythm to provide fluid symptom control while preventing overstimulation, ultimately helping you reclaim more "good" time and independence.

Parkinson’s Diet

There is no single ‘Parkinson’s diet,’ but certain food choices can help manage symptoms and overall well-being. A balanced diet rich in fruits, vegetables, and whole grains supports general health and may help reduce inflammation.

Plant-based flavonoids, present in berries, citrus fruits, and broccoli, which have antioxidant effects, can help protect brain cells from damage. Drinking enough water can support digestion and prevent dehydration.

Ultimately, small, consistent dietary choices, combined with medical guidance, can make a meaningful difference in managing symptoms.

Parkinson’s disease is a journey, and the earlier the signs are recognized, the better the condition can be managed. If you or a loved one is experiencing persistent changes in sleep, smell, or movement, do not wait for the symptoms to become overwhelming. Consulting a neurologist is the first step toward taking back control of your health.