Credits: Canva
Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.
She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.
While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.
A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.
While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.
Pasricha suggests acetaminophen.
However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.
NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.
A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.
Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".
Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.
An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.
A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.
Credits: Canva
Can Chinese medicine cure baldness? Baldness has long been dealt as a matter of shame over health. Products focus on hiding the bald patch rather than curing it. Baldness has in the past made global headlines when South Korean president Lee Jae Myung said 'Baldness is the new enemy' and suggested that insurance should cover the treatment as a part of medical treatment.
Androgenetic alopecia (AGA), better known as pattern hair loss, is the most common form of hair thinning worldwide. While medications like finasteride and minoxidil remain the standard line of treatment, concerns around side effects, lifelong use, and mixed results have led many people to explore gentler, more holistic alternatives.
A new scientific review now suggests that Polygonum multiflorum—a root used in traditional Chinese medicine for over a thousand years—may hold real promise in managing AGA. Historically described as a remedy that can “blacken hair and nourish essence,” the herb is gaining renewed attention as modern research begins to unpack how it actually works at a biological level.
Most conventional hair-loss treatments target a single biological mechanism. Polygonum multiflorum, however, appears to work on several fronts at once. According to the review, the herb helps reduce the activity of dihydrotestosterone (DHT), a hormone strongly associated with hair follicle shrinkage in AGA.
At the same time, it protects hair follicle cells from premature cell death and activates key growth-related signalling pathways, including Wnt and Sonic Hedgehog (Shh), both crucial for maintaining a healthy hair growth cycle. The herb may also improve scalp blood circulation, potentially enhancing the delivery of oxygen and nutrients to hair follicles—an often overlooked factor in hair thinning.
“Our analysis bridges ancient wisdom and modern science,” said Han Bixian, the lead author of the review published in the Journal of Holistic Integrative Pharmacy. “What surprised us was how consistently historical texts—from the Tang Dynasty onward—described effects that align closely with today’s understanding of hair biology.”
The researchers examined a wide range of evidence, including laboratory studies, clinical observations, and historical herbal literature. Together, these sources suggest that Polygonum multiflorum does more than simply slow hair loss—it may actively support healthier hair function.
One of the most striking findings is the herb’s potential role in hair regeneration. Rather than only delaying further thinning, Polygonum multiflorum appears to influence multiple growth factors involved in restarting and sustaining the hair cycle. This broader mode of action could give it an edge over treatments that focus on just one biological target.
The review notes that when properly processed—a critical step in traditional preparation, the herb shows a relatively favorable safety profile. This could make it more appealing to patients concerned about side effects such as sexual dysfunction or scalp irritation commonly linked to existing medications.
That said, the authors stress the need for more high-quality clinical trials to confirm effectiveness, establish safe dosing, and standardize preparation methods. Even so, the findings highlight how rigorous scientific study of traditional remedies can uncover new possibilities for treating common conditions like androgenetic alopecia.
Credits: Canva
As artificial intelligence becomes a go-to source for quick answers, a new University of Oxford-led study on AI chatbots and medical advice is raising serious concerns about how safe it is to rely on these tools for health guidance.
The research suggests that while AI chatbots can provide medical information, their advice is often inaccurate, inconsistent, and difficult for users to interpret, potentially putting people at risk—especially when dealing with symptoms that need urgent care.
The study involved 1,300 participants who were given realistic health scenarios, such as experiencing a severe headache or being a new mother feeling constantly exhausted. Participants were divided into two groups: one group used AI chatbots to understand their symptoms and decide next steps, while the other did not.
Researchers then assessed whether participants correctly identified what might be wrong and whether they made appropriate decisions, such as seeing a GP or visiting A&E.
The results were troubling. People who relied on AI frequently failed to identify the severity of their condition and were often unsure about when to seek professional medical help.
According to the researchers, one major issue is that people don’t always know what to ask. The study found that chatbot responses varied widely depending on how questions were phrased. Even small changes in wording could lead to completely different answers.
The AI often produced a mix of helpful and misleading information, leaving users to decide which advice mattered. Many participants struggled to distinguish between reliable guidance and unnecessary or confusing details.
As one of the study’s authors explained, when an AI lists multiple possible conditions, users are left guessing which one applies to them—precisely the moment where mistakes can happen.
Dr Rebecca Payne, lead medical practitioner on the study, warned that asking chatbots about symptoms could be “dangerous”, particularly when users delay seeking professional care based on AI responses.
Dr Adam Mahdi, the study’s senior author, noted that while AI can share medical facts, people often share information gradually and leave out key details—something chatbots struggle to manage effectively.
Experts also point out that chatbots are trained on existing medical data, which means they may repeat long-standing biases baked into healthcare systems. As one psychiatry expert put it, a chatbot is only as accurate as human clinicians—and humans are far from perfect.
That said, not everyone is pessimistic.
Digital health experts argue the technology is evolving. Health-specific versions of general AI chatbots have recently been released by major developers, and these could perform differently in future studies.
The consensus among experts is clear: AI in healthcare should focus on improvement, regulation, and guardrails, not replacement of doctors. Used responsibly, it may support healthcare—but without safeguards, it risks doing more harm than good.
Credits: Harm and Evidence Research Collaborative and Association for Women In Science
This common pregnancy drug could be linked to cancer. Wes Streeting has been urged to launch a public inquiry into a miscarriage drug called Diethylstilbestrol, which, reports say has "ruined and devastated" the lives of countless women. On Monday, the Health Secretary Streeting met victims of the pregnancy drugs, which has been linked to cancer, early menopause and infertility.
Diethylstilbestrol, commonly known as DES, is a synthetic form of female hormone estrogen, which was prescribed to thousands of pregnant women from 1940 to 1970s.
The drug was used to prevent miscarriage, premature labor and complications of pregnancy. This was also used to suppress breast milk production, as an emergency contraception and to treat symptoms of menopause.
In 1971, Diethylstilbestrol (DES) was linked to a rare cancer of the cervix and vagina known as clear cell adenocarcinoma, prompting US regulators to advise that it should no longer be prescribed to pregnant women. Despite this, the drug continued to be given to expectant mothers across parts of Europe until 1978. DES has also since been associated with other cancers, including breast, pancreatic and cervical cancers, The Telegraph reported.
Campaign group DES Justice UK (DJUK) is now urging Health Secretary Wes Streeting to order a public inquiry and introduce an NHS screening programme to identify people who may have been exposed to the drug before birth.
Victims described DES as “one of the biggest pharmaceutical scandals this country has ever seen,” warning that “the impact of this terrible drug cannot be underestimated as it has ruined and devastated so many lives,” according to The Telegraph.
In November, Streeting acknowledged that the “state got it wrong” and issued an apology to those affected. He also advised anyone who believes they may have been exposed to DES to speak to their GP.
Susie Martin, 55, from Manchester, whose mother was prescribed DES during pregnancy, told The Telegraph she has undergone between 20 and 30 operations as a result of the drug’s effects.
“The impact of this terrible drug cannot be underestimated as it has ruined and devastated so many lives, including my own,” she said. “The physical and emotional pain has been unbearable. I live with a constant fear that I will need more surgery or develop cancer—and I am far from the only one.”
Calling DES a “silent scandal,” Martin said she hopes the government’s engagement will lead to concrete action. “While I welcome Mr Streeting meeting us, it will only matter if he commits to meaningful steps for victims of this shameful chapter in British medical history, including a screening programme and a full statutory public inquiry,” she added.
The Telegraph reported that compensation schemes have been set up for DES victims in the US and Netherlands, however, UK does not have one yet.
"There are harrowing accounts of harm caused by the historic use of Diethylstilbestrol (DES). Some women and their relatives are still suffering from the associated risks of this medicine which have been passed down a generation, and haven’t been supported. The Secretary of State has been looking seriously at this legacy issue and carefully considering what more the government can do to better support women and their families who have been impacted. NHS England has alerted all cancer alliances to this issue so that healthcare professionals are aware of the impacts of DES and the existing NHS screening guidance which sets out the arrangements for those who show signs and symptoms of exposure,” said a Department of Health and Social Care spokesman to The Telegraph.
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