Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.

What happens when you consume pain killers?

She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.

While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.

A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.

What can be done?

While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.

Pasricha suggests acetaminophen.

However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.

Why is it a concern?

NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.

A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.

Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".

Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.

An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.

A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.

While HPV vaccines are most known for preventing cervical cancer, a top US doctor says they can also help curb the rising incidence of head and neck cancers.

According to Mikkael A. Sekeres, Chief of the Division of Hematology and Professor of Medicine at the Sylvester Comprehensive Cancer Center at the University of Miami, Human papillomavirus (HPV) — the same sexually transmitted virus that can infect the genital area and lead to cervical cancer — is now the greatest risk factor for head and neck cancer.

Writing in The Washington Post, Sekeres noted that HPV accounts for about 30 per cent of oropharyngeal cancer worldwide.

HPV is believed to be responsible for the recent rise in head and neck cancers, which include malignancies affecting the mouth and throat (oral cavity and pharynx), voice box (larynx), sinuses and nasal cavities, and salivary glands.

Sekeres said the US records about 60,000 new cases of head and neck cancers each year, while the global incidence is expected to rise by 30 per cent by 2030.

What Are The Risk Factors?

The expert noted that men develop oral cavity and pharynx cancers at approximately 2.5 times the rate of women.

Major risk factors include:

• Tobacco use, including smoking, secondhand smoke and smokeless tobacco
• Chewing areca nut, also known as betel quid
• Heavy alcohol consumption
• HPV infection

Also read: PM Modi Launches Nationwide Free HPV Vaccination Drive; A Landmark Step, Says WHO

The Centers for Disease Control and Prevention (CDC) estimates that the high-risk HPV subtypes most associated with head and neck cancers are detectable in the mouths of 4 per cent of adults aged 18 to 69.

While a pap test detects early-stage cervical cancer in women, no such test exists for penile, anal, or head and neck cancers in men, which can worsen their survival rate.

HPV Vaccination Best Prevention Strategy

Thus, Sekeres said: “The best way to prevent the most common types of HPV is through vaccination, with two doses of the vaccine recommended for children at age 11 or 12, or starting as early as 9 years and up to age 26 for those who missed it as a child".

He noted that although the vaccine is approved for use up to age 45, it is generally less beneficial after age 26 because many individuals may have already been exposed to HPV. However, doctors can help determine whether vaccination may still be beneficial for adults.

Earlier this year, the European Cancer Organization also urged broader HPV vaccination regardless of gender.

“HPV affects everyone, regardless of gender. It can lead to cancers of the cervix, mouth and throat, anus and penis. This is why universal protection is so important,” the organization said in a social media post.

Read More: Who Needs HPV Vaccine? Guide For Every Parent, Teen And Adult

HPV Vaccine Can Boost Cancer Risk

A 2026 study published in JAMA Oncology found that boys and men who received the HPV vaccine between the ages of 9 and 26 were nearly 50 per cent less likely to develop cancers of the head and neck, esophagus, anus, or penis.

The findings, based on data of more than 510,000 boys and men, highlight the importance of vaccinating all children and adolescents against HPV, said Taito Kitano, first author of the study and a researcher at Nara Prefecture General Medical Center in Japan.

“Children, adolescents, parents and health care workers should be more informed about the expected benefits of the HPV vaccine, not just cervical cancer,” Kitano said.

FIFA has launched a groundbreaking initiative aimed at advancing research and knowledge to boost health and performance of female athletes.

The FIFA Female Health and Performance Project comes ahead of the tenth edition of the FIFA Women's World Cup, which is scheduled to take place in Brazil next year.

The initiative aims to provide specialist, science-based educational resources tailored to the preparation and development of female athletes. It also seeks to close long-standing gaps in understanding the unique health and performance needs of female players, many of whom still lack access to the scientific data needed to support their development and optimize performance.

“FIFA’s aim is to optimize every female footballer’s health, well-being and performance, and to improve knowledge around women and girls in football at every level of the game,” said Sarai Bareman, FIFA’s Chief Women’s Football Officer.

“Collectively, we can do so much more to better support our growing number of female players and ensure they are trained, supported and understood according to their specific needs as women.”

Why Is The Initiative Significant?

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A study analyzing 5,261 research articles published in sport and exercise science journals between 2014 and 2020 found that only 34% of study participants were female, while just 6% of sport science research focused exclusively on women.

Only 8% of elite female athletes have sufficient knowledge about how the menstrual cycle may affect training and performance.

Many training methodologies, workload models and performance benchmarks used in sport have historically been derived from male athlete data, requiring female athletes to adapt to systems that may not accurately reflect their physiological characteristics.

What Will The Project Achieve?

The initiative is designed to provide a comprehensive understanding of the female athlete, her individual needs, her environment and the tailored support required to optimize health and performance.

The educational modules cover universal topics in football and elite sport science, including sleep, recovery, strength and conditioning, all examined through the lens of the female athlete.

Female-specific topics such as physiology, pregnancy, postpartum health and menopause are also included.

Four separate learning levels — from “Introduction” to “Integrated” — provide tailored information for a wide range of audiences, from sports professionals to members of the general public.

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In addition to improving access to knowledge and education, the initiative aims to break taboos, normalize language, eliminate social stigma, encourage open communication and establish a supportive environment in which female athletes can thrive.

“We need to normalize conversations around female health and embrace this, using it to our advantage instead of ignoring it or being fearful of discussing it,” Bareman added. “It is not a weakness; it is a strength.”

Key areas covered by the project include:

• Female physiology
• Reproductive years
• Menstrual health tracking
• Pregnancy and postpartum health
• Fertility
• Menopause
• Pelvic health
• Nutrition
• Recovery
• Sleep
• Strength and conditioning
• Screening and profiling
• Injury and injury prevention

Who Will Benefit?

Available to all through FIFA’s Training Centre platform, the FIFA Female Health and Performance education modules are the result of collaboration with leading experts to generate, curate and apply the scientific evidence underpinning the program.

All 211 FIFA Member Associations will have access to specialised, peer-reviewed, science-based information through 13 tailor-made educational modules.

UK-based journalist Emma Barnett said it took 21 years to receive a diagnosis of endometriosis, a chronic condition in which tissue similar to the uterine lining grows outside the womb.

The condition, which causes severe pain and other complications, affects one in 10 women. However, diagnosis remains difficult and is often dismissed as merely “painful periods”.

“It’s a disease that has outwitted doctors and researchers around the world. No one knows what causes it. No one knows how to cure it. At least 1 in 10 women are staggering about with it,” Barnett shared in a post on Instagram.

“Endometriosis may not typically kill women, but it’s a living death for many. It is a silent medical emergency,” she added.

The 41-year-old BBC journalist said: “It’s a scandal it takes nearly 10 years to be diagnosed — in my case 21 years.”

Living With Debilitating Pain

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There is currently no cure for endometriosis. Available treatments include hormone therapy, predominantly the contraceptive pill, to manage symptoms, or surgery, including hysterectomy in severe cases.

“I’ve been suffering from the condition — in which tissue similar to the womb lining, that’s meant to leave your body, grows and builds outside the uterus — since my periods started at the age of 10. But it would be more than 20 years until I’d be diagnosed at 31, after two years of trying to get pregnant naturally, which meant more than 20 years of enduring excruciating, bone-grinding pain without ever having a label for it,” she wrote in Women's Health magazine.

She described the pain “as a drilling sensation from my pelvis that travels down my legs — making them feel as though I can’t lift them to go up the stairs. Sometimes, the hurt spreads to my arms or chest, and comes with crippling nausea and loss of appetite. I also run cold; freezing even. It’s like someone turned the heating off in my body”.

A Documentary To Expose A Neglected Disease

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Recognizing that many women experience similar struggles, Barnett made a new documentary film "Emma Barnett: Fighting Endometriosis" in which she speaks with women, including doctors, researchers and even politicians about their experiences with endometriosis, highlighting a neglected disease that has no known cure.

Through the documentary, Barnett hopes to raise awareness of the condition, improve public understanding, and draw attention to the long delays many women face in receiving a diagnosis.

“One of the reasons I have made a film about endometriosis is that I want people to understand it is not just ‘painful periods’. It’s a system-wide inflammatory condition where tissue similar to the lining of the uterus grows outside of it, causing agonizing pain. I am hoping to boost public understanding of that, and beyond merely being able to pronounce it,” she wrote in The Independent.

“It’s very hard to make something invisible visible, but what I am trying to do with this film is bring the invisible into light and show that this is a silent emergency.”