Many of us may have taken ibuprofen, sometimes two pills at once, especially when we are struggling with menstrual cramps. Well, as good these pills may be in treating the pain, they are not recommended for your health, especially if you are someone who consumes it on a daily basis or frequently. Gastroenterologist Trisha Pasricha, MD, writes in The Washington Post about why should you avoid taking nonsteroidal anti-inflammatory drugs, or NSAIDs, such as ibuprofen, naproxen and aspirin.

What happens when you consume pain killers?

She writes that NSAIDs are great in treating short term pain. They comprise of a group of drugs that inhibit the production of prostaglandins, which serve as a variety of purposes in the body. Some of which also includes contracting the uterus during menses and regulating blood flow in our vessels.

While one to two doses every now and then is okay, following a regular dosage routine, which could range from several times a month, or twice in an hour or so could lead to health risk. NSAIDs are well known to increase intestinal permeability. This means, these painkillers could damage the lining of your gut.

A 2018 review by Ingvar Bjarnason et. al., also writes about how NSAIDs can reduce the blood flow in the tiny vessels that feeds our guts. It can also disrupt the intestinal cells forming a barrier between the outside world and your insides.

What can be done?

While people with conditions like migraines, chronic back pain or bad period cramps can find NSAIDs to be helpful. It is always advisable to have a chat with your physicians to explore NSAID alternatives.

Pasricha suggests acetaminophen.

However, if someone is in dire need of NSAID, her tip is to take the pill right at the start of your symptoms. She says that the drug can do a far better job at stopping things at the source than chasing after all prostaglandins.

Why is it a concern?

NSAIDs are available as over the counter drug, which means people do not need a prescription for it and can make medical decision about them without the guidance of a physician.

A 2018 study published in the Official Journal of the International Society for Pharmacoepidemiology by David W Kaufman, et.al., found that 15% of adult ibuprofen users in the US have exceeded the maximum recommended daily dose. The study also mentions that more than a third of ibuprofen users were taking other NSAIDs, like aspirin and naproxen, while consuming ibuprofen at the same time. Out of these, 61% did not realise that they were using NSAIDs.

Pasricha talks about how it ruptures the gut wall, as she herself has rushed to the hospital in the middle of the night "far more times than" she can count "to perform an emergency endoscopy on someone who was bleeding profusely from an ulcer caused by NSAID".

Another 2009 study published in the American Journal of Gastroenterology states that as many as 1 in 4 chronic NSAID users will get an ulcer and about 4% will bleed or rupture through the gut wall.

An older study from 2005 titled A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy, found that as 75 percent of people regularly using NSAIDs develop low-grade inflammation in their small bowels. NSAIDs can also lead to development of fatty liver disease. This happens because your gut lining becomes more permeable, more toxins and bacteria from the outside world enters your liver and leads to inflammation.

A 2011 study titled Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials, states that as many as 6% of people taking NSAIDs regularly have found their blood count dropping within a few months of starting the medicines, this suggests that this is due to the small, slow amount of bleeding in the gut overtime.

While you may have seen multiple women, who are not pregnant, taking prenatal vitamins to improve their skin, hair and nail quality, experts say you should steer clear and only stick to multivitamins to ensure your body stays healthy all-year round.

Prenatal vitamins are daily supplements for women who are pregnant or trying to get pregnant. These supplements contain the vitamins and minerals you need to support healthy fetal development, according to the Cleveland Clinic.

Dr Rohan Palshetkar, Consultant IVF Specialist, Bloom IVF tells Healthandme: ""Prenatal vitamin should be taken three months at least prior to the pregnancy or basically whenever you begin to start planning the pregnancy, ensure that all your micro nutrients as well as your folic acid levels are up to the normal mark so as to ensure that your baby has a healthy growth"

But when your body doesn't need it, taking supplements could put you at risk over time.

Which Vitamins And Minerals Are Prenatal Vitamins Rich In?

As per the American College of Obstetricians and Gynecologists (ACOG), here are the most important nutrients prenatal vitamins are packed with:

Folic Acid: One of the most important prenatal nutrients, this B vitamin is important as it creates your baby's neural tube. This is the structure that eventually forms brain. As per the US Preventive Services Task Force, folic acid supplements significantly increase the growth of healthy neural tube. The American Academy of Pediatrics also notes that it helps the neural tube to protect from defects by 50 percent.

Iron: It supplies blood and oxygen to the fetus and also helps build the placenta. It also gives the mother extra blood volume that you need throughout pregnancy. Pregnant people are prone to anemia, this is why iron supplementation is a must.

Calcium: The most time spend in uterus for a baby is invested in building their bones and teeth, this is a Herculean task, and requires the mother to have plenty of calcium. If you don't have enough calcium, then your baby will utilise the calcium from your body, which could lead to temporary bone loss.

Certain prenatal supplements also contain other additives such as omega-3 fatty acids.

Why Is It Dangerous To Take Prenatal Vitamins

The main difference between a prenatal vitamin and a multivitamin is the concentration of folic acid and iron.

Ingesting enough folate from food or folic acid from supplements at the start of a pregnancy lowers the risk of certain birth defects. Along with this, iron supplements help the body make the extra blood cells needed during pregnancy.

The amount of folic acid suggested for people who are planning a pregnancy is 400 to 800 micrograms (mcg) a day. The amount of iron needed in pregnancy is 27 milligrams (mg) a day.

The typical amount of folic acid for an non-pregnant adult is 400 mcg a day. For iron, the typical daily amount is 8 mg for males and 18 mg for females.

Taking iron and folic acid at levels higher than the suggested amounts may bump people closer to the upper limit for these nutrients which can raise the risk of health problems.

Taking too much folic acid, especially over 1,000 mcg daily without a doctor's advice, can mask a vitamin B12 deficiency, potentially causing irreversible nerve damage and may lead to side effects such as bitter taste, nausea or sleep problems, with potential links to increased risks in pregnancy like autism or insulin resistance.

Eating too much iron, especially from supplements, can cause acute iron poisoning, leading to severe nausea, vomiting, abdominal pain, diarrhea and bloody stools. Long-term excessive intake causes iron to deposit in tissues, causing iron overload (hemochromatosis) that damages the liver (cirrhosis), heart (failure), and pancreas (diabetes) and may cause a bronze skin color.

Non-alcoholic fatty liver disease, often called fatty liver, occurs when excess fat builds up in the liver due to reasons unrelated to alcohol consumption. Multiple studies suggest that nearly 35 to 40 percent of Indian adults may already be living with fatty liver disease. Experts believe this figure could be a conservative estimate, making it a growing public health concern.

What is even more worrying is that Indians are significantly more prone to developing fatty liver disease compared to many other ethnic groups.

A Genetic Link Rooted in Survival

Dr Alok Chopra, a cardiologist and functional medicine expert with over four decades of experience, recently explained in an Instagram video why Indians are disproportionately affected.

“This is not just about junk food or sitting all day,” Dr Chopra said. “People from the Indian subcontinent developed a survival mechanism over generations of famine. Our bodies learned to store fat quickly, especially in the liver, to protect us during periods of starvation.”

According to him, this genetic adaptation has outlived its usefulness in modern times. “The famine disappeared, but the genetic switch never turned off,” he explained. “That is why today nearly one in three Indians is estimated to have fatty liver disease, and the real number may actually be closer to half the population.”

Why Fatty Liver Often Goes Unnoticed

Fatty liver disease is often called a silent condition because it may not cause obvious symptoms in its early stages. Many people discover it accidentally during routine blood tests or ultrasound scans. If left unchecked, it can progress to liver inflammation, fibrosis, or even cirrhosis.

Dr Chopra warns that ignoring early signs can be risky, but he also offers reassurance.

The Liver Can Heal If Given the Right Support

“The good news is that fatty liver is one of the most reversible conditions,” he said. “The liver is a remarkable organ. It detoxifies, regenerates, and supports metabolism, hormones, and energy. But it needs the right environment to heal.”

According to him, early action through lifestyle and nutrition changes can make a significant difference before the disease progresses.

Three Simple Steps to Reverse Fatty Liver

Dr Chopra outlines three key strategies to support liver health.

First, he advises aligning eating habits with the body’s natural rhythms. “Eat your dinner early, avoid late-night snacking, and include periods of intermittent fasting,” he said. “This is how our ancestors naturally lived.”

Second, he stresses the importance of cooking fats. “Your grandmom was right,” he noted. “Use ghee instead of refined seed oils. Bad oils, corn syrups, and highly processed foods push the liver towards inflammation and fat storage.”

Lastly, he highlights antioxidants. “Glutathione is the body’s master antioxidant,” Dr Chopra explained. “You can also support it with berries, dark leafy greens like spinach and kale, colorful vegetables, and even coffee, which research shows can lower the risk of fatty liver.”

With awareness and timely action, fatty liver disease does not have to be permanent.

Note: This is a user-generated content available publicly. It is not a substitute of medical consultation.

Bajau Sea Nomads have evolved beyond human limits. But how is that even possible? Remember Charles Darwin's theory of natural selection? The survival of the fittest? This is what kept the Bajau Sea Noamds going, and evolving.

The Bajau people are sea nomads who survive by collecting shellfish from the sea floor. They come from South-East Asia, and study shows that they have developed bigger spleen for diving. They are known as 'Sea Gypsies' and are known to hold their breath for over five minutes, whereas highly trained professionals can hardly hold their breath for three to four minutes. Bajau divers spend hours underwater for fishing. They are also the world's only community of self-sufficient sea nomads, reported The Guardian.

How The Bajau Sea Nomads Evolved: What Does The Study Say?

A study published in the academic journal Cell notes that the effect of their underwater lifestyle reflected on their biology. Their spleens were larger than those of other people from the region.

How The Bajau Sea Nomads Evolved: How Does A Spleen Work?

Tucked just beside the stomach, the spleen is roughly the size of a fist and usually flies under the radar. Its everyday job is to filter old red blood cells from the blood. But under the right conditions, it can also act like a built-in oxygen reserve.

This hidden ability is especially important for the Bajau people, often called “sea nomads,” who live across parts of the southern Philippines, Indonesia and Malaysia. Numbering roughly a million, the Bajau have relied almost entirely on the ocean for generations.

“For possibly thousands of years, they have been living on houseboats, travelling from place to place in the waters of South-East Asia and visiting land only occasionally,” said Melissa Ilardo from the University of Copenhagen, speaking to the BBC’s Inside Science. “Everything they need, they get from the sea.”

Read: A Genetic Disorder Caused This Indonesian Tribe To Have Sparkling Blue Eyes

How The Bajau Sea Nomads Have Evolved?

The Bajau are known for their extraordinary free-diving abilities. When diving in the traditional way, they spend up to eight hours a day at sea, with around 60 percent of that time underwater. Individual dives can last anywhere from 30 seconds to several minutes, often reaching depths of more than 70 metres.

What makes this even more remarkable is the equipment. Many Bajau divers use little more than a wooden mask or simple goggles and a weight belt. No oxygen tanks, no wetsuits, no modern diving aids.

This lifestyle prompted researchers to ask whether the Bajau body has adapted over time to support such extreme breath-hold diving.

According to Dr Ilardo, the spleen was an obvious place to look. Humans, like many marine mammals, have a natural “dive response” that kicks in when we hold our breath and submerge ourselves in water, especially cold water.

“When this response is triggered, your heart rate slows down,” she explained. “Blood vessels in your arms and legs constrict to preserve oxygen-rich blood for vital organs like the brain and heart.”

The final part of this response involves the spleen.

How The Bajau Sea Nomads Evolved: An enlarged Spleen Boosts Oxygen

The spleen acts as a reservoir for oxygenated red blood cells. When it contracts during a dive, it releases these cells into the bloodstream, giving the body a temporary oxygen boost.

“It’s like a biological scuba tank,” Dr Ilardo said.

For people like the Bajau, who dive repeatedly every day, this spleen contraction can make a crucial difference, helping them stay underwater longer and recover faster between dives.

In short, what seems like an ordinary organ plays an extraordinary role, revealing how the human body can adapt in remarkable ways to extreme environments.