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You’ve waved goodbye to cookies, chips, and everything else that comes in a shiny wrapper, but the scale refuses to budge. It can be disheartening when cutting out processed foods doesn’t translate into immediate weight loss.
While eliminating junk food is an essential first step, weight loss often requires more nuanced adjustments. Studies, including a 2019 publication in Cell Metabolism, reveal that processed foods can lead to increased calorie consumption — about 500 extra calories daily compared to whole, unprocessed diets. While cutting out junk food is a commendable step, achieving sustainable weight loss requires a holistic approach.
But sometimes, ditching junk food isn’t enough. Here are five key reasons why your weight loss journey may be stalling, and how you can get back on track.
The connection between sleep and weight is often overlooked but crucial. Both too much sleep (over 9 hours) and too little (under 5 hours) can disrupt your body’s production of appetite-regulating hormones, such as leptin and ghrelin. This hormonal imbalance can increase cravings and overeating, particularly for high-calorie foods.
Additionally, poor sleep can leave you feeling fatigued, making it harder to stick to exercise routines.
How to Fix It: Aim for 7–8 hours of quality sleep per night. Establish a consistent bedtime routine and minimize screen time before bed to improve sleep hygiene.
You may have switched to a "healthier" drink lineup, but beverages like fruit juices, sugary coffee drinks, and wine can contain hidden calories that derail progress. Even organic fruit juices, often marketed as healthful, are loaded with sugar and lack the fiber found in whole fruits.
How to Fix It: Stick to water, unsweetened tea, black coffee, or sparkling water. To manage hunger, drink two cups of water 30 minutes before meals—a strategy backed by research in the Journal of Natural Science, Biology and Medicine. Treat calorie-laden drinks as occasional indulgences rather than daily staples.
When and how often you eat can significantly influence weight loss. Skipping meals can lead to overeating later, while constant grazing throughout the day can result in unnoticed calorie overload.
Studies show that front-loading your calories, with a substantial breakfast and lighter evening meals, promotes greater weight loss. Research published in the journal Obesity found that individuals consuming larger breakfasts lost twice the weight compared to those who favored bigger dinners.
How to Fix It: Stick to eating every 3.5 to 4 hours during a 10–12-hour daytime window. This approach stabilizes blood sugar and encourages fat reserves to be used for energy between meals.
Exercise is a cornerstone of weight loss, but it’s easy to overestimate the calories burned and indulge in post-workout treats. That post-spin class protein shake or granola bar may negate your calorie deficit if not balanced within your daily intake.
How to Fix It: Plan snacks strategically. If your workout falls within two hours of a meal, skip the extra snack and refuel during your regular meal. If you need a snack, opt for small, protein-rich options like Greek yogurt or a handful of nuts.
Water plays an underrated role in weight loss. Staying hydrated helps control hunger and reduces the temptation to reach for sugary drinks. Dehydration, on the other hand, can be mistaken for hunger, leading to unnecessary snacking.
How to Fix It: Drink 2–6 cups of water daily to satisfy thirst without adding calories. Carry a reusable water bottle as a visual reminder to stay hydrated throughout the day.
Sitting for long hours, whether at a desk or on the couch, can slow your metabolism and disconnect your body’s natural hunger cues. Incorporating even short bursts of activity, like three 10-minute walks daily, can reignite your metabolism.
Stress often leads to comfort eating, favoring calorie-dense, nutrient-poor foods. Mindfulness practices, such as meditation or journaling, can help address the emotional triggers behind overeating.
Medical conditions, genetics, or hormonal imbalances can also impede weight loss. If your efforts yield no results, consult a healthcare professional for tests or guidance tailored to your needs.
Weight loss isn’t linear, and small, consistent adjustments are more effective than drastic overhauls. By identifying and tackling these hidden barriers, you can set yourself up for lasting success on your health journey.
Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain. Cell Metabolism. 2019
Effect of excessive water intake on body weight, body mass index, body fat, and appetite of overweight female participants. J Nat Sci Biol Med. 2014
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A recent study suggests that a person’s blood group could play a role in whether they are more likely to develop severe liver conditions. Although most of us link blood type only with transfusions or donor matching, scientists now believe it may also offer clues about long-term liver health.
A new study published in the journal Frontiers reports that individuals with blood group A have an increased chance of autoimmune liver disorders. In these conditions, the body’s own immune system mistakenly harms liver tissue, which can lead to ongoing damage and, in some cases, life-threatening liver failure.
The researchers also found that people with blood group B may have a slightly lower likelihood of certain liver-related concerns compared with those who have type A.
Scientists have long examined how inherited blood groups relate to different illnesses. Some earlier findings noted that individuals with non-O blood types (A, B, or AB) tend to show higher activity of certain clotting factors and other changes in the body.
These differences may affect blood flow in the liver. For example, past studies found slightly increased levels of a clotting protein called von Willebrand factor in people with advanced liver disease who had non-O blood types, although it does not appear to be a major driver of risk.
The latest research focused on autoimmune liver diseases such as:
Among these, autoimmune hepatitis showed a stronger link with blood group A. Blood group B appeared to carry a somewhat lower chance of PBC when compared with type A.
Several earlier studies explored the relationship between blood group and liver cancer (hepatocellular carcinoma or HCC). Older data and a large meta-analysis found that people with type O blood were under-represented among those with liver cancer, suggesting that type O may be tied to a lower risk overall.
Understanding your blood group can offer insight into potential health risks, though it does not mean you will certainly develop liver disease if you are type A or B. It remains only one part of a larger picture.
This may be especially important if you have blood type A or B and a family history of liver conditions. Routine health checks, liver screenings, and discussions with your doctor can help you watch for any early signs.
For now, it is clear that blood type is more than a simple classification, as it may hold useful information about future liver health.
Autoimmune liver disorders are uncommon, yet they can become serious when they are not spotted in time. A better grasp of the genetic and immune-related factors behind them can guide stronger prevention and treatment efforts. The authors of the study note that more research involving larger and more varied groups of people is needed to confirm these findings and to explain how different ABO blood types may influence the development of autoimmune liver problems.
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According to the International Diabetes Federation, roughly one in nine adults worldwide lives with diabetes, and around 90% of these cases are type 2 diabetes. There is currently no cure for type 2 diabetes. Still, the condition can be managed through healthy lifestyle habits, such as staying active, as well as medication. One widely used medication is metformin, considered a first-line therapy for type 2 diabetes, and it has been prescribed for decades since the Food and Drug Administration (FDA) approved it in 1994. Recent research, however, suggests it may also act directly on the brain, opening the door to new approaches to treatment.
Scientists at Baylor College of Medicine in the US have discovered a brain pathway that metformin appears to influence, alongside its known effects on other parts of the body. "It has been widely believed that metformin lowers blood sugar mainly by reducing glucose production in the liver. Other studies have also highlighted its action in the gut," says Makoto Fukuda, a pathophysiologist at Baylor.
As reported by Science Alert, the researchers explained, "We turned our attention to the brain, given its central role in regulating overall glucose metabolism. Our goal was to understand whether and how the brain contributes to metformin’s anti-diabetic effects."
Earlier research by some of the same scientists had pinpointed a protein in the brain called Rap1, which influences glucose metabolism, especially in a region called the ventromedial hypothalamus (VMH).
In their 2025 study, experiments on mice showed that metformin reaches the VMH, where it helps combat type 2 diabetes by essentially shutting down Rap1. When mice were genetically modified to lack Rap1, metformin no longer affected a diabetes-like condition—even though other medications still worked. This provides strong evidence that metformin acts in the brain through a mechanism distinct from other drugs.
The researchers also examined which specific neurons metformin interacts with. This could eventually pave the way for treatments that target these neurons directly. "We found that SF1 neurons are activated when metformin enters the brain, indicating they are directly involved in the drug’s effect," they said.
While generally safer than many other type 2 diabetes medications, metformin does have side effects. Gastrointestinal issues such as nausea, diarrhea, and stomach discomfort affect up to 75% of users. Other risks can arise when there are underlying conditions like kidney problems, which may compound health concerns.
Metformin is also recognized as a gerotherapeutic—a medication that may slow aging processes in the body. For instance, it has been shown to reduce DNA damage and support gene activity linked to longer life.
Previous studies indicate that metformin can also protect the brain from wear and tear and may even lower the risk of long COVID, according to Science Direct.
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Delhi NCR is already facing one of its toughest air-quality crises, and now another worry has emerged. Volcanic ash from Ethiopia’s Hayli Gubbi volcano has started drifting toward Indian skies. BBC reports that ash clouds from this rare eruption have reached Delhi, raising concerns about health risks in a city where clean air is already hard to come by due to rising pollution. As this volcanic ash moves closer, people fear it could worsen existing respiratory problems.
In Delhi, where the Air Quality Index (AQI) often falls in the “very poor” or “severe” range, even small increases in particulate matter can have serious health effects. Understanding what volcanic ash can do and taking the right precautions can help reduce its impact.
A volcano in northern Ethiopia erupted on Sunday for the first time in nearly 12,000 years. Winds blowing at 100–120 km/h carried ash plumes to several countries. The Hayli Gubbi volcano in Ethiopia’s Afar region erupted Sunday morning, and by late last night, ash clouds reached Delhi, which is already struggling with toxic air, causing some disruption to flights.
The ash plumes, rising thousands of feet into the atmosphere, first passed over Gujarat and then moved toward Rajasthan, Delhi, Haryana, and Punjab. According to the India Meteorological Department (IMD), the ash clouds are drifting toward China and are expected to clear from Indian skies by 7:30 pm.
Volcanic smog, also called “vog,” is generated whenever a volcano erupts. Global health bodies like the World Health Organization (WHO) and the US Centers for Disease Control and Prevention (CDC) have long studied its effects. Here’s what you need to know about how volcanic ash can impact health.
Volcanic ash is made of fine particles that can reach deep into the lungs. According to the US Geological Survey’s Impacts & Mitigation guidelines, inhaling these particles can lead to:
Even healthy individuals may experience shortness of breath or discomfort after heavy exposure. For those with pre-existing lung conditions, the effects can be much more serious.
IMD Director General M. Mohapatra stated that the plume is approaching Delhi NCR, but “any significant impact on ground-level pollution is unlikely” because most of the ash is high in the atmosphere. He added that the ash cloud may appear as a cloudy, hazy sky for a few hours as it moves eastwards.
Meteorologists and weather analysts have noted that the plume contains volcanic ash, sulphur dioxide, and tiny glass or rock particles. It is moving quickly, at around 100–200 km/h, according to reports.
Dr Aditya Nag, Assistant Professor, Department of Respiratory Medicine, NIIMS Medical College and Hospital, told us that even if most of the ash remains high in the sky, fine particles can settle on the ground and mix with Delhi’s already polluted air. Components like ash and sulphur dioxide can irritate the lungs, throat, and eyes.
Dr. Manav Manchanda, Director & Head – Respiratory, Critical Care & Sleep Medicine, Asian Hospital, told us that people most at risk include children, the elderly, and anyone with asthma or COPD. Volcanic ash can also pose environmental risks, such as reducing visibility or damaging engines.
“Abrasive particles in the volcanic ash can trigger bronchospasm in COPD and asthma patients, making their condition worse,” said Dr Aditya Nag.
Dr. Manav Manchanda, advise the same safety measures that apply during high pollution days:
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