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You’ve waved goodbye to cookies, chips, and everything else that comes in a shiny wrapper, but the scale refuses to budge. It can be disheartening when cutting out processed foods doesn’t translate into immediate weight loss.
While eliminating junk food is an essential first step, weight loss often requires more nuanced adjustments. Studies, including a 2019 publication in Cell Metabolism, reveal that processed foods can lead to increased calorie consumption — about 500 extra calories daily compared to whole, unprocessed diets. While cutting out junk food is a commendable step, achieving sustainable weight loss requires a holistic approach.
But sometimes, ditching junk food isn’t enough. Here are five key reasons why your weight loss journey may be stalling, and how you can get back on track.
The connection between sleep and weight is often overlooked but crucial. Both too much sleep (over 9 hours) and too little (under 5 hours) can disrupt your body’s production of appetite-regulating hormones, such as leptin and ghrelin. This hormonal imbalance can increase cravings and overeating, particularly for high-calorie foods.
Additionally, poor sleep can leave you feeling fatigued, making it harder to stick to exercise routines.
How to Fix It: Aim for 7–8 hours of quality sleep per night. Establish a consistent bedtime routine and minimize screen time before bed to improve sleep hygiene.
You may have switched to a "healthier" drink lineup, but beverages like fruit juices, sugary coffee drinks, and wine can contain hidden calories that derail progress. Even organic fruit juices, often marketed as healthful, are loaded with sugar and lack the fiber found in whole fruits.
How to Fix It: Stick to water, unsweetened tea, black coffee, or sparkling water. To manage hunger, drink two cups of water 30 minutes before meals—a strategy backed by research in the Journal of Natural Science, Biology and Medicine. Treat calorie-laden drinks as occasional indulgences rather than daily staples.
When and how often you eat can significantly influence weight loss. Skipping meals can lead to overeating later, while constant grazing throughout the day can result in unnoticed calorie overload.
Studies show that front-loading your calories, with a substantial breakfast and lighter evening meals, promotes greater weight loss. Research published in the journal Obesity found that individuals consuming larger breakfasts lost twice the weight compared to those who favored bigger dinners.
How to Fix It: Stick to eating every 3.5 to 4 hours during a 10–12-hour daytime window. This approach stabilizes blood sugar and encourages fat reserves to be used for energy between meals.
Exercise is a cornerstone of weight loss, but it’s easy to overestimate the calories burned and indulge in post-workout treats. That post-spin class protein shake or granola bar may negate your calorie deficit if not balanced within your daily intake.
How to Fix It: Plan snacks strategically. If your workout falls within two hours of a meal, skip the extra snack and refuel during your regular meal. If you need a snack, opt for small, protein-rich options like Greek yogurt or a handful of nuts.
Water plays an underrated role in weight loss. Staying hydrated helps control hunger and reduces the temptation to reach for sugary drinks. Dehydration, on the other hand, can be mistaken for hunger, leading to unnecessary snacking.
How to Fix It: Drink 2–6 cups of water daily to satisfy thirst without adding calories. Carry a reusable water bottle as a visual reminder to stay hydrated throughout the day.
Sitting for long hours, whether at a desk or on the couch, can slow your metabolism and disconnect your body’s natural hunger cues. Incorporating even short bursts of activity, like three 10-minute walks daily, can reignite your metabolism.
Stress often leads to comfort eating, favoring calorie-dense, nutrient-poor foods. Mindfulness practices, such as meditation or journaling, can help address the emotional triggers behind overeating.
Medical conditions, genetics, or hormonal imbalances can also impede weight loss. If your efforts yield no results, consult a healthcare professional for tests or guidance tailored to your needs.
Weight loss isn’t linear, and small, consistent adjustments are more effective than drastic overhauls. By identifying and tackling these hidden barriers, you can set yourself up for lasting success on your health journey.
Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain. Cell Metabolism. 2019
Effect of excessive water intake on body weight, body mass index, body fat, and appetite of overweight female participants. J Nat Sci Biol Med. 2014
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As 2025 comes to an end, one thing is clear, this year has been a year of remarkable shifts in how we understand health. This year, there have been breakthroughs, redesigns, and achievements in the healthcare sector, which has changed many lives. Scientists and doctors have pushed their boundaries in ways to save lives, make patients more comfortable and Health and Me lists down 5 such breakthroughs that defined the year 2025.
Few medical tools have stayed as frozen in time as the vaginal speculum. Cold, metallic, and intimidating, its origin traces back to Dr. James Marion Sims in the mid-19th century, during experiments carried out unethically on enslaved women. Beyond its history, patients have long reported pain, anxiety, and emotional distress linked to it. But this year, a young design team dared to ask what would happen if pelvic exams could feel safe.

Enter Lilium, a flower-inspired speculum created by Delft University engineers Tamara Hoveling and Ariadna Izcara Gual. Made with soft plastic and shaped to bloom like a lily, it opens gently, eliminates the harsh clicking sound, and uses a tampon-like applicator for insertion. Designed to feel familiar and symbolically comforting, Lilium represents a shift toward trauma-informed, patient-first gynecological care—something long overdue.
For 28-year-old Sahil Mehra from Mumbai, a severe, drug-resistant Pseudomonas infection left his kidneys failing and his doctors nearly out of options. Even last-resort antibiotics couldn’t stop the superbug.
Then came Zaynich, India’s first new antibiotic in more than three decades. Developed by Wockhardt, it combines cefepime, a fourth-generation cephalosporin, with zidebactam, a novel β-lactam enhancer that boosts the drug’s power against tough bacteria. Early reports and trials suggest a 97% effectiveness against drug-resistant Gram-negative bacteria and even a 20% higher cure rate than meropenem in Phase 3 studies. Within four days of receiving Zaynich, Mehra’s condition stabilized—a reminder of why antibiotic innovation is essential in the age of superbugs.
High LDL cholesterol remains one of the biggest drivers of cardiovascular disease. While statins help, many people never reach target levels. Injectable PCSK9 inhibitors work well but remain expensive and less accessible.
This year, an experimental daily pill—enlicitide—showed promise of changing that equation. In the Phase 3 CORALreef Lipids trial involving 2,912 adults, enlicitide reduced LDL-C levels by 55.8% at 24 weeks, with post-hoc analysis suggesting reductions up to 59.7%. With a safety profile similar to placebo, enlicitide could become the first oral PCSK9 inhibitor to make potent cholesterol control easier and more widely available.
A Shenzhen-based biotech company sparked global debate by claiming it has developed a pill that targets ageing at the cellular level. The pill focuses on clearing “zombie cells”—old cells that refuse to die and trigger inflammation. Made with compounds derived from grape seeds, early animal lab work suggests potential lifespan extension. While far from proven in humans, the idea that such a pill could stretch life to 120–150 years captured the world’s imagination and intensified conversations around longevity science.
With dengue cases hitting record levels globally, Brazil approved the world’s first single-dose dengue vaccine, called Butantan-DV. Developed by the Butantan Institute in collaboration with Wu Xi, it uses a live attenuated virus and is currently approved for ages 12 to 59. Until now, the only dengue vaccine required two doses months apart. This single-shot version could transform dengue prevention, especially in tropical countries facing surges linked to rising temperatures.
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Recently the news of Norovirus outbreak in an AIDA cruise that has infected more than 100 guests and crew on board made news. This is the 21st outbreak, as confirmed by the Centers for Disease Control and Prevention (CDC). This case has brought back memories from the Royal Caribbean Cruise outbreak, where 94 out of 1,874 and 4 crew members also were infected by Norovirus.
This virus is also known as the 'rib-cracking' winter virus, which sets it apart from rest of the winter viruses. People who have been sickened by this contagious virus are vomiting explosively, which may make the sufferers to experience a cracking in their ribs, which is where it gets its name 'rib-cracking' winter virus.
The virus typically spikes after the holidays, when families gather indoors. However, new data from the Centers for CDC shows this year’s surge has arrived weeks ahead of schedule, and experts say there’s no obvious explanation yet.
According to the CDC, 12.5 percent of norovirus tests came back positive during the week of November 22, nearly identical to the 13 percent positivity rate the week before. Compared to two weeks earlier, infections have jumped by about 25 percent. But the real number of cases is likely far higher, as most people with norovirus never get tested.
Between August 1 and November 13, health officials recorded 153 norovirus outbreaks, more than double last year’s 69 during the same period, and far above the 65 reported in 2023.
The CDC estimates the U.S. sees around 2,500 outbreaks every year. An outbreak is recorded when two or more people fall ill from a suspected or confirmed shared source.
On cruise ships, which are closely monitored by federal agencies, outbreaks have also been climbing. The AIDAdiva, a German vessel currently on a long global route, recently reported a spike in cases. In a statement to USA TODAY, AIDA Cruises said it has increased hygiene measures on board and that infections are already declining.
“Seasonal illness peaks between November and April, and the AIDAdiva report reflects what we’re seeing on land,” the cruise line said.
Norovirus infects roughly 21 million Americans every year and sends about 2 million to hospitals or clinics. It spreads easily through contaminated food, surfaces, shared utensils, or direct contact with an infected person. Even a tiny amount of virus can trigger illness.
Symptoms usually appear within 12 to 48 hours and include nausea, vomiting, diarrhea, stomach cramps, and sometimes fever and chills. The biggest danger is dehydration, which can set in quickly. Severe fluid loss can lead to low blood pressure, reduced organ perfusion, electrolyte imbalances, and in extreme cases, seizures or fainting.
The virus contributes to about 900 deaths in the U.S. annually, mostly among older adults.
Doctors emphasize that hand sanitizers don’t reliably kill norovirus. Frequent handwashing with soap and water is the best protection.
The season’s lowest positivity rate was recorded in early August at 6.5 percent. But with holiday travel and gatherings underway, health officials warn infections are likely to rise.
The symptoms usually begin 12 to 48 hours after your first exposure to the virus and could last from 1 to 3 days. You can, however, continue to shed virus in your stool for several week after your recovery. The shedding could go up for months if you have another medical condition.
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Delhi woke up again to a thick layer of smog, with Delhi's AQI hovering over 300 on the Air Quality Index on Thursday morning under "very poor" category. After a long nine-day wait, city's AQI had slipped under "poor" category on Tuesday, but it is again back on the "very poor" category, while on Wednesday, there were strong winds that dispersed the pollutants. Yet the condition of the air quality remains bad.
As a result of this many people are leaving the city, or have at least considered leaving the city.
Nikita Singh, 31, who runs a remote PR boutique agency was living in Delhi on and off for two years because it was two years back when she struggled to breathe during Delhi winters. "The pollution levels were so extreme that I felt breathless and constantly fatigued. That was the first time I seriously questioned whether I could continue living here long-term," she says.
For the first two years, she kept "oscillating". "I would stay in Delhi for work during peak months, then leave when pollution became unbearable, especially from November to January. Every return felt heavier. I had my eyes burning, headaches, chest tightness and a general feeling of 'I cannot do this forever'."
She has now permanent moved away from Delhi to Jodhpur, in Rajasthan, where she works remotely. However, it has not been easy on her. "Emotionally, it was tough because Delhi had become familiar, and my life and work circle were mostly based there," she says. However, thanks to her fully remote work and that fact that she had decided to prioritize her health, she was able to make the move.
She says that Jodhpur offers the cleaner air which she "never felt in Delhi". Her decision to move also came with her family uprooting from Delhi. "My family and I shifted together. AQI was a major trigger. We realized we could not keep exposing ourselves to those levels of pollution year after year," she reveals.
She is not alone, Vikash Makkar, a freelance linguist specialist and a journalist, who had been living in Delhi from the last 12 years, moved back to his hometown in Jamshedpur. "Since October with an unplanned journey, I moved to my hometown and have been living there. It is quite relaxed here as compared to Delhi's ongoing pollution crisis that I had faced," he shares.
29-year-old Riya Baibhawi also uprooted from the city. She had been living in Delhi from last 5 years. She is currently living in Ludhiana, Punjab, and her decision to leave city is also affected by the pollution. Though, it was not easy for her. "It was very tough because it was very difficult to find career opportunities with competitive salaries outside Delhi-NCR. It also required a cut down of my social life, which adversely affected my mental health," she says. She shares that one of her friends, who had been living in Noida for the last 20 years had also moved out as pollution exacerbated her asthma.
Another family, who have been living in Delhi's Karol Bagh for more than two decades now are considering moving out of Delhi. "They are looking for properties outside Delhi where air is cleaner," shares their 26-year-old daughter who now lives in her marital home in Noida.
As per a survey by a consumer insights platform Smytten PulseAI, about 34.6% of the residents surveyed in Delhi NCR have considered to move out of the city due to worsening air. A 2023 study published in the International Journal of Environmental Research and Public Health shows that if the level of PM2.5 increases by 10µg/m3, migrants coming into the city will be reduced by 21.2%. While migration in the city has been ongoing, pollution does show some strains of people moving out of the city.
As per the Air Quality Life Index released by the Energy Policy Institute at the University of Chicago (EPIC), the fine particulate matter or PM2.5 in air will shorten an average Indian's life expectancy by 5.3 years, and in Delhi, it could shorten a person's life span by 11.9 years. However, the Union government has said in the parliament that there is "no conclusive national data to establish a direct correlation between deaths or diseases occurring exclusively due to air pollution". This statement comes at a time when doctors themselves noted a surge in cases due to pollution and have urged people to leave the cities.
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