A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.

What Did The Study Find?

The researchers examined the blood of two groups of healthy male donors in their 60s:

• One group had donated blood three times a year for 40 years.
• The other group had donated only about five times in total.

The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.

How Can Blood Donation Affect Stem Cells?

As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.

However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.

Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.

Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.

Read More: Who Can Donate Blood To Whom?

Limitations

One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.

Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.

Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.

Also Read: How Long After a Tattoo or Piercing Can I Donate Blood?

Students gaming more than 10 hours a week can have long-lasting negative effects on their physical and mental health, a new Australian study suggests.

Researchers from Curtin University, Perth have found that playing online games for over 10 hours can worsen diets, increase body weight and led to poorer sleep than lighter gamers.

Professor Mario Siervo, Curtin School of Population Health said of the results: "What stood out was students gaming up to 10 hours a week all looked very similar in terms of diet, sleep and body weight. The real differences emerged in those gaming more than 10 hours a week, who showed clear divergence from the rest of the sample."

What Did The Study Find?

Researchers surveyed 317 students across five Australian universities, with a median age of 20, to understand how time spent gaming each week might affect their diet, sleep, and body composition.

Students were categorized as low gamers (zero to five hours a week), moderate gamers (five to 10 hours) or high gamers, who played video games for more than 10 hours each week.

They found that low and moderate gamers showed largely comparable health outcomes but health indicators deteriorated sharply among students whose gaming time exceeded 10 hours a week.

The study found diet quality declined and obesity was more common once gaming exceeded 10 hours a week, with each extra hour linked to poorer diets even after accounting for other lifestyle factors. While high gamers recorded a body mass index (BMI) of 26.3kg/m2, low and moderate gamers fell within a healthier range, with median BMIs of 22.2kg/m2 and 22.8kg/m2 respectively.

Professor Siervo said: "Each additional hour of gaming per week was linked to a decline in diet quality, even after accounting for stress, physical activity and other lifestyle factors."

Additionally, sleep quality was generally poor across all groups but students who played video games for moderate or high amounts of time reported worse sleep than low gamers.

Despite clear results, the expert added that the study does not prove cause and effect but shows excessive gaming is linked to higher health risks, while low to moderate play appears largely fine.

Why Is Playing Video Games Bad For You?

"Our data suggests low and moderate gaming is generally fine, but excessive gaming may crowd out healthy habits such as eating a balanced diet, sleeping properly and staying active.

"Because university habits often follow people into adulthood, healthier routines such as taking breaks from gaming, avoiding playing games late at night and choosing healthier snacks may help improve their overall well-being," Professor Siervo said.

Playing video games for excessive amount of time has also been linked to paving the way for mental health problems such as anxiety, depression, aggression and poor emotional control as well as social/life problems including neglecting responsibilities, isolation, poor relationships, academic/career impact.

Moreover, previous research has also found that playing games for over three hours straight significantly raises the risk of physical issues. Sessions exceeding this time frame can lead to eye fatigue, headaches, neck pain and wrist pain, regardless of the player's age or gender.

This study was published in Nutrition on January 16.

Days after eagle-eyed fans spotted Nick Jonas stepping out of the Golden Globes during the Nikki Glaser-hosted show in Los Angeles, the popstar has now revealed what led to him there.

In an X video from January 11, Jonas was seen standing alone outside of a tent at the Beverly Hilton hotel surrounded by palm trees and green foliage, looking like he was taking a breather while sipping from a glass bottle of water and rubbing his chin.

As the clip began to go viral online, users shared their guess on why he had to exit the ceremony, commenting, "Social anxiety got the best of him." Soon after, he did reveal that he anxiety had "hit him like a gut punch" on X.

Living with Type 1 diabetes, Jonas has previously spoken about the emotional challenges of managing a chronic condition and how it has affected his life.

What Is Social Anxiety?

As explained by Dr Sanil Sinhasan, Consultant Psychiatrist at Mind Care Clinic and SRV Hospital, Mumbai, to Health Shots: "Social anxiety disorder is an intense fear of being judged, rejected, or embarrassed in social or performance situations.

"People with social anxiety often worry excessively about how they look, speak or are perceived by others."

This kind of anxiety is typically triggered by meeting new people, public speaking or even everyday interactions like eating in public, stemming from fears of negative evaluation by others.

Symptoms include blushing, sweating, trembling, rapid heartbeat, nausea, dizziness, trouble speaking, stomach issues. If left untreated, social anxiety can become debilitating as it can also cause fast, shallow breathing, muscle tension, suffocation, symptoms that can intensify anxiety further and lead to serious medical events.

How To Overcome Social Anxiety?

Professional therapies such as Cognitive Behavioral Therapy (CBT) and medication such as antidepressants (SSRIs/SNRIs) can offer deeper solutions for managing fear and building skills.

Regular physical activity can also help release endorphins and reduce tension as well avoiding excess caffeine can support mental health.

Mental health experts also recommend opening up to loved ones and avoiding isolation. Speaking to loved ones and sharing how you’re feeling can help ensure your current state doesn’t aggravate.

Doctors also advise speaking therapist if social anxiety significantly impacts your life as professional help is crucial for lasting change.

Wondering if abnormal bleeding, pelvic pain and leg swelling are signs of something fatal?

According to Dr Ninad Katdare, Consultant Surgical Oncologist, Jaslok Hospital & Research Centre, they may be symptoms of cervical cancer. While many may expect drastic signs such as severe pain, heavy bleeding or obvious illness, identifying certain symptoms can help with early diagnosis and treatment.

Cervical cancer develops in a women's cervix (uterus opening) due to abnormal cell growth, primarily caused by persistent HPV infection, a common infection that's passed through sexual contact.

When exposed to HPV, the body's immune system typically prevents the virus from causing damage however, in a small percentage of people, the virus can survive for years and pave the way for some cervical cells to become cancerous.

Treatment involves surgery, radiation, and chemotherapy, with early detection significantly improving outcomes, though it remains a major cancer in low-income countries. Cervical cancer can also be prevented through vaccination and regular screening (Pap/HPV tests).

Dr Katdare told News18: "In its early stages, it is often more of a whisper than a shout. As a cancer surgeon who has treated hundreds of women with gynaecological cancers, I can say with confidence that recognising these subtle cues can lead to earlier diagnosis and significantly better outcomes."

He recommends looking out for these early signs:

1. Intermenstrual Bleeding

2. Changes In Vaginal Discharge

But Dr Katdare warns that any sudden or abnormal changes in discharge may be a symptom of the cancer. “Because discharge issues are commonly linked to infections, many women self-medicate or delay seeking care," he said. “While infections are far more common, chronic or unusual discharge especially in older women requires thorough evaluation."

Discharge may become persistent, watery, foul-smelling, or tinged with blood or pink, brown, or rust-colored if you're suffering from this kind of cancer.

3. Persistent Pelvic Pain

Consistent pelvic pain particularly that occurs outside the menstrual cycle or during sexual intercourse should be a point of concern. According to Dr Katdare, "Pain during intercourse, or dyspareunia, is especially important. It should not be dismissed as ‘just dryness’ or an age-related change. In cervical cancer, this pain may result from inflammation or tumour growth involving the cervix and surrounding tissues."

4. Leg Swelling

5. Urinary And Bowel Symptoms

“These symptoms are often evaluated in isolation because they don’t seem related to the cervix," said Dr Katdare, “which can delay the correct diagnosis."

Ultimately the expert advised: "“Cervical cancer does not always announce itself loudly,. Sometimes, it leaves silent clues. The sooner you listen to them, the better the outcome. If something feels ‘off,’ trust that instinct and seek medical advice. Early action can make the difference between a curable disease and a life-altering diagnosis."