Regular Blood Donation May Influence Cancer Risk

Updated Mar 12, 2025 | 11:00 PM IST

SummaryAs and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow.
Can blood donation reduce cancer risk?

Credits: Canva

A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.

What Did The Study Find?

The researchers examined the blood of two groups of healthy male donors in their 60s:

  • One group had donated blood three times a year for 40 years.
  • The other group had donated only about five times in total.

The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.

How Can Blood Donation Affect Stem Cells?

As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.

However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.

Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.

Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.

Read More: Who Can Donate Blood To Whom?

Limitations

One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.

Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.

Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.

Also Read: How Long After a Tattoo or Piercing Can I Donate Blood?

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What Happens When You Log Off From Facebook And Instagram?

Updated Apr 30, 2026 | 04:01 PM IST

SummaryFacebook users over 35 showed the biggest mood improvements, while among Instagram users, the 18-to-24 group benefited most.
What Happens When You Log Off From Facebook And Instagram?

Credit: Canva

Ever tried logging off social media platforms like Facebook and Instagram? For many, checking notifications, scrolling through feeds, and engaging with content has become second nature, often leading to an unnoticed addiction.

While digital dependence can significantly impact mental health, relationships, and overall well-being, most people don’t realize how much time they’re actually spending online.

To understand its effects, researchers at Stanford University in the US asked the 36,000 study participants to log off on weekends from their Facebook and Instagram accounts. The results showed that the people who stayed off felt measurably better.

Disconnecting from social media was seen as a powerful way to regain balance and focus in the increasingly connected world.

The study split participants into groups: about 275 were paid to deactivate their accounts for six weeks, while others logged off for just one week. Both groups showed improved emotional well-being compared to those who kept scrolling, but the effect was more pronounced for Facebook users who went longer without it.

Facebook users over 35 showed the biggest mood improvements, while among Instagram users, the 18-to-24 group benefited most.

Also read: Is India Set To Implement A Social Media Ban For Children?

Social Media And Mental Health

An increasing number of studies and the community at large are convinced that social media are detrimental to our mental health and general well-being.

According to a recent YouGov poll taken in the UK in January 2026, 37 percent of adults gave a general negative review of social media's impact on their mental health, more than twice the number of people who say otherwise.

Merely 14 percent of them admitted to receiving a positive effect from social media on their mental health.

The Pew Research Center survey, conducted in 2024, discloses that 45 percent of US teenagers think social media is damaging their sleep, and 40 percent believe it is hurting their productivity, which are both key factors of mental health.

In 2023, former US Surgeon General Vivek Murthy named social media as a major threat to the mental health of teens. He also released a social media advisory about social media and mental health.

The advisory indicates that frequent social media use could be associated with changes in parts of the brain related to emotions and learning. Additionally, it can affect impulse control, social behavior, emotional regulation, and sensitivity to social punishments and rewards.

Read More: The Cost Of Social Media Addiction: Study Says It Can Give Kids Eating Disorders

In serious cases, social media can also contribute to self-harm or suicidal thoughts, especially among teens and children facing cyberbullying or trolling. Young people are particularly vulnerable to online pressures, negative comparisons, and feelings of rejection.

“Excessive social media exposure has been linked to anxiety, depression, sleep disruption, and, most importantly, difficulty with regulating attention and emotions. Algorithms intensify comparison, validation-seeking, and exposure to harmful content, which children lack the maturity to process,” Dr. Sachin Pradeep Baliga, Associate Consultant Mental Health & Behavioural Sciences, Fortis Healthcare, told HealthandMe.

Is Quitting The Only Option?

According to mental health experts, moderation and mindfully controlled usage could be the key.

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It is far more effective to come up with a plan that helps your interaction with social media platforms be healthier, such as limiting your time on social media platforms, avoiding harmful content, and pursuing real-world connections, rather than completely demonizing social media.

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AIIMS Patna Study Unravels Brain’s Critical Link In Heatstroke Deaths

Updated Apr 30, 2026 | 10:30 AM IST

SummaryThe finding can be a major step forward in the scientific basis for diagnosing heat stroke deaths through post-mortem examination, an area that has often posed challenges for autopsy surgeons in establishing a definitive cause of death, the researchers said.
AIIMS Patna Study Unravels Brain’s Critical Link In Heatstroke Deaths

Credit: iStock

A team of researchers at the All India Institute of Medical Sciences (AIIMS) in Patna has made a significant breakthrough in understanding the link between heatstroke and fatalities.

The study published in the Medico-Legal Journal identified a specific brain center and vascular injury patterns that play a crucial role in heatstroke-related deaths.

The research team discovered that the anterior hypothalamus, which serves as the brain's primary temperature-regulating center, undergoes severe structural damage during heatstroke. This damage is found to be a key factor in the fatal outcomes associated with heatstroke.

“The study establishes that the anterior hypothalamus undergoes critical structural damage during heat stroke, making it a central driver of fatal outcomes. The injury in the hypothalamus can be used as definitive evidence in the forensic diagnosis of heat-stroke deaths,” said lead author Dr Ashok Kumar Rastogi, forensic expert, in a statement.

The finding can be a major step forward in the scientific basis for diagnosing heat stroke deaths through post-mortem examination, an area that has often posed challenges for autopsy surgeons in establishing a definitive cause of death, the researchers said.

It will also help address a long-standing medico-legal issue, particularly in the context of compensation, insurance claims, and death benefits for the families of victims.

How Was The Study Conducted?

The study was conducted by the Department of Forensic Medicine at AIIMS Patna in collaboration with the Department of Anatomy and Pathology.

The study was based on detailed post-mortem investigations of individuals exposed to extreme environmental conditions in the Patna region during 2024, including temperatures reaching 48 degrees Celsius, humidity levels up to 95 per cent, and prolonged heat exposure lasting five to eight hours, the Institute said.

The results also outlined a vascular injury pattern associated with fatal heat stroke, helping build a clearer pathological profile of the condition under extreme heat exposure.

The researchers noted that the findings could strengthen forensic investigations and support more scientifically grounded death certification in suspected cases.

Heatstroke is a medical emergency with a high case fatality rate. The body’s inability to regulate internal temperature and eliminate heat gain in such conditions increases the risk of heat exhaustion and heatstroke.

Speaking to HealthandMe, Dr. Naval Vikram, Professor, Department of Medicine, at the AII India Institute of Medical Sciences (AIIMS), explained how heat stroke affects people.

“The general features of a patient with heat stroke are: first, his or her body temperature will be very high. It will not be around normal levels like 104, 105, or 106—it will be significantly elevated. Second, the person may be delirious, confused, or even in a state of unconsciousness or coma. The breathing will also be labored. These are the features of heat stroke,” Dr Vikram said.

The most vulnerable category for heat-related problems is the extremes of age—the younger children and older adults. The expert noted that younger children may not be able to express their symptoms completely. They may not be able to tell you exactly what they are feeling.

At the other end, older adults often have multiple health issues—neurological conditions, diabetes, hypertension, and kidney problems.

How Can One Prevent?

Try to avoid exposure to extreme heat as much as possible.

Adequate hydration is key.

One must cover the head and upper body, use an umbrella, stay hydrated, and take breaks in between.

If you have to work in a hot environment for a couple of hours, take a break in a cooler or temperature-controlled environment for at least half an hour before resuming, rather than continuously working in the heat.

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Donald Trump’s Discolored Left Hand Triggers Health Speculation: Expert Explains

Updated Apr 30, 2026 | 12:00 AM IST

SummaryEarlier, the US President informed that he takes aspirin doses more than his doctors recommend, and that is the reason for the bruising seen on his right hand.
Donald Trump’s Discolored Left Hand Triggers Health Speculation: Expert Explains

Credit: X/Aaron Rupar

Recent photographs of former US President Donald Trump with the UK’s King Charles III have drawn attention after visible discoloration was observed on his left hand, raising fresh questions about his health.

While Trump’s right hand has appeared discolored in earlier public appearances—a concern previously downplayed by both the former president and the White House—the latest images show similar changes on his left hand as well.

“Trump's right hand has been in bad shape for a long time now, but this picture taken today shows discoloration on the back of his left hand," independent journalist Aaron Rupar wrote on social media platform X.

Speaking to HealthandMe, Dr. Amit Prakash Singh, Consultant - Internal Medicine at the CK Birla Hospital, Delhi, explained the possible underlying causes that can result in hand discoloration. He noted that the condition may be due to:

  • Bruising (bleeding under the skin)

This appears as blue, purple, or black patches. It may occur due to minor trauma or sometimes even spontaneously. The use of blood thinners or antiplatelet agents like aspirin can increase the likelihood of bruising. With age, blood vessels become more fragile, making bruising more common.

  • Low oxygen or poor circulation
Hands may appear blue or dusky when the blood reaching them has reduced oxygen levels. This can be triggered by cold weather, blood vessel spasms (as seen in conditions like Raynaud’s), or underlying heart and lung conditions. Medically, this is called cyanosis.

  • Swelling (fluid buildup in tissues)
Hands may look puffy or feel tight. Causes can include kidney, heart, or liver conditions, excess salt intake, certain medications, or poor lymphatic drainage.

  • Infection or inflammation
This presents as red, warm, and painful swelling, often accompanied by fever, and requires prompt medical attention.

Dr. Singh advised people "to be concerned if there is sudden swelling in one hand, severe pain or tightness, persistent blue or black discoloration, breathlessness, fever with redness and warmth, or numbness and weakness".

"A purple or blue patch often suggests bruising, blue fingers may indicate circulation or oxygen issues, puffy hands suggest fluid retention, and red, hot swelling points toward infection," the expert said.

However, there is no official medical update on the discoloration in Trump's left hand. Therefore, any claims remain speculative. But it is not the first time that various speculations have been going around about the health of Trump.

Also read: Heat Stroke or Heat Exhaustion? AIIMS Doctor Explains Key Symptoms, How To Prevent

In an interview with The Wall Street Journal, in January this year, the US President informed that he takes aspirin doses more than his doctors recommend, and that is the reason for the bruising seen on his right hand. He has repeatedly said that his health is in "excellent" condition.

In the interview, he said, "They say aspirin is good for thinning out the blood, and I don't want thick blood pouring through my heart."

Trump, now 70, was diagnosed with chronic venous insufficiency, a condition that occurs when veins have trouble moving blood back to the heart. He also showed signs of bruising on his hand, which many attributed to frequent handshaking and to the use of aspirin.

Aspirin may still be considered for some people under 60 or 70 who have a higher risk of heart disease, but this decision should be made carefully. Factors like high blood pressure, high cholesterol, diabetes, smoking history, or a strong family history can influence whether aspirin makes sense for an individual.

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