A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.

What Did The Study Find?

The researchers examined the blood of two groups of healthy male donors in their 60s:

• One group had donated blood three times a year for 40 years.
• The other group had donated only about five times in total.

The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.

How Can Blood Donation Affect Stem Cells?

As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.

However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.

Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.

Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.

Read More: Who Can Donate Blood To Whom?

Limitations

One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.

Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.

Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.

Also Read: How Long After a Tattoo or Piercing Can I Donate Blood?

When John Cena started noticing blurry vision, he assumed it was simply part of getting older. But the worsening eyesight was also accompanied by redness, itchiness and crusting around his eyes.

“I had a lot of redness and itchiness, and every once in a while, waking up with eye crusties and stuff. At the same time, given my age — I'm 49 now — my vision was going a little bit, so I just figured it was par for the course. But because my vision was going, I needed to see if I needed glasses or prescriptions.”

Until then, Cena had delayed getting his eyes checked. He believed that the symptoms were caused by bright lights, excessive screen time or ageing.

However, an eye examination gave him a surprise. Cena learned that his symptoms were caused by Demodex blepharitis, a condition he says he had never heard of.

“Diagnosed with Demodex blepharitis, which I didn't even know existed.”

What Are Demodex Mites?

Also read: Study Decodes Why COVID Survivors Continue To Suffer Vision Problems

Demodex mites are tiny, eight-legged organisms that live naturally on human skin, particularly around hair follicles. Measuring just 0.15 to 0.4 millimeters, they are invisible to the naked eye but are present on the skin of almost every adult.

These microscopic mites feed on sebum (the skin's natural oil) and dead skin cells, helping remove accumulated debris under normal conditions.

How Do Demodex Mites Work?

Demodex mites are most active at night. They emerge from hair follicles after sunset because ultraviolet (UV) light is harmful to them. While people sleep, the mites feed, crawl and reproduce on the skin's surface.

They are also believed to be stimulated by melatonin, the hormone that helps regulate sleep, creating a unique relationship between humans and these naturally occurring organisms.

When Can Demodex Mites Become A Problem?

Although harmless in small numbers, Demodex mites can cause problems if they multiply excessively—a condition known as demodicosis.

According to Dr. Richard Locksley, professor of medicine at the University of California, San Francisco, an overgrowth of Demodex mites can contribute to:

• Rosacea
• Blepharitis (eyelid inflammation)
• Acne-like breakouts
• Itchy, inflamed skin

Read More: Wegovy More Likely To Cause Rare Blindness Than Ozempic And Other Similar Drugs, Recent Study Finds

People with weakened immune systems are particularly vulnerable because their bodies may be less able to control mite populations. In addition, inadequate sleep may increase oil production, providing more nourishment for the mites.

Should You Be Worried?

For most healthy people, Demodex mites are a normal part of the skin microbiome and are not considered harmful. Problems generally arise only when their numbers increase significantly.

To help reduce the risk of overgrowth:

• Wash your face every night with a gentle, non-comedogenic cleanser to remove excess oil and debris.
• Remove eye makeup and false eyelashes before bed, as these can encourage mite buildup.
• Get adequate sleep, since poor sleep may increase sebum production.
• Consult a dermatologist if you experience persistent redness, itching or inflammation around the eyes or skin.

Common Sports Injuries and How to Prevent Them by Dr Sumit Batra. Whether you're training for a marathon, playing pickleball with friends, or simply trying to stay fit at the gym, being active is one of the best things you can do for your health. But every sport is unique and places different demands on your body. Without the right preparation, even a fun weekend workout can leave you with an injury that keeps you on the sidelines. Often, I see people whose injuries could have been avoided by warming up properly, increasing their training slowly, and paying attention to pain. Many think the pain will go away on its own, but getting it checked early can help prevent bigger problems.

Several types of common sports injuries show up suddenly, while others build up over time. Ankle sprains are among the most common. They usually happen when the foot rolls awkwardly during running, jumping, or changing direction quickly. Simultaneously, Knee injuries are another common problem, especially in sports that involve sudden stops, pivots, or jumps, so the ligaments, cartilage, or tendons around the knee can be affected, making movement painful and unstable.

Muscle strains in the hamstrings and calves often occur when muscles are pushed harder than they're ready for. Skipping a warm-up or increasing the intensity of your workouts too quickly can raise the risk.

Athletes who play cricket, tennis, or volleyball, or who spend long hours swimming, may also develop shoulder pain due to repeated overhead movements. And then there are overuse injuries like tennis elbow, shin splints, and Achilles tendinitis, which develop slowly after repeated stress without enough recovery.

How to Reduce Your Risk

The good news is that most sports injuries can be prevented. Start every workout with a proper warm-up. Just five to ten minutes of light movement and stretching can help prepare your muscles and joints for exercise.

Strength training is equally important. Strong muscles support your joints, improve balance, and help your body absorb the impact of running, jumping, and lifting.

It's also important not to rush your progress. Whether you're preparing for a race or trying heavier weights, increasing the intensity little by little gives your body time to adapt safely.

Recovery deserves just as much attention as training. Good sleep, proper hydration, balanced meals, rest days, and well-fitting sports shoes all play a role in keeping injuries away.

Listen to What Your Body Is Telling You

Always listen to your body—it often gives warning signs before it's too late. Feeling sore after a challenging workout is completely normal. But pain that doesn't improve, swelling, difficulty putting weight on a limb, or restricted movement shouldn't be ignored. Getting the injury checked early often means a quicker recovery and lowers the chances of long-term problems. Sports injuries can happen to anyone, whether you are a seasoned athlete or someone who enjoys staying active on weekends. A little preparation, sensible training, and adequate recovery can go a long way in preventing them. And if something doesn't feel right, don't wait for it to get worse. Early care can make all the difference in getting you back to doing what you love.

Dr. Sumit Batra, Consultant Orthopaedic & Spine Surgeon at PB Health

Gone are the days when constipation was considered a problem only among older adults. Today, an increasing number of young professionals are experiencing irregular bowel movements, bloating, abdominal discomfort, and a constant feeling of incomplete evacuation. The fast-paced corporate lifestyle, long working hours, unhealthy eating habits, and chronic stress have made constipation a common digestive concern among people in their 20s and 30s.

One of the biggest contributors is a sedentary lifestyle. Many professionals spend eight to ten hours sitting at a desk, with little time for physical activity. Regular movement helps stimulate bowel function, and a lack of it can slow down digestion. Another common cause is poor dietary habits. Skipping breakfast, relying on processed or fast foods, and consuming inadequate amounts of fibre can significantly affect bowel health.

Hydration also plays a vital role. Busy schedules often lead people to consume more coffee or tea while neglecting water intake. Dehydration makes stools harder and more difficult to pass, increasing the risk of constipation. Stress is another major factor. Deadlines, work pressure, and poor sleep can disrupt the communication between the brain and the gut, affecting normal bowel movements. Ignoring the natural urge to pass stools due to meetings or travel can further worsen the condition over time.

The good news is that constipation can often be managed through simple lifestyle changes. A balanced diet rich in fibre from fruits, vegetables, whole grains, legumes, and nuts helps add bulk to stools and promotes regular bowel movements. Drinking at least two to three litres of water daily keeps stools soft and easier to pass.

Regular physical activity is equally important. Even a brisk 30-minute walk, stretching during work breaks, or choosing stairs over elevators can improve gut motility. Maintaining a consistent toilet routine, preferably after breakfast, and responding promptly to the body's natural urge can also help establish healthy bowel habits.

Stress management should not be overlooked. Practising yoga, meditation, deep breathing exercises, or simply ensuring adequate sleep can positively influence digestive health. Limiting excessive consumption of processed foods and caffeinated beverages can also reduce the risk of constipation.

While occasional constipation is usually not a cause for concern, persistent symptoms lasting more than three weeks, severe abdominal pain, blood in the stool, unexplained weight loss, or constipation alternating with diarrhoea should never be ignored. These could indicate an underlying medical condition that requires evaluation by a gastroenterologist.

Healthy digestion is closely linked to overall well-being and productivity. By adopting healthier daily habits and paying attention to digestive health, young professionals can prevent constipation, improve their quality of life, and maintain better physical and mental performance at work.

By Dr. Pradeepta Kumar Sethy, Director, Gastroenterology, Manipal Hospital, EM Bypass & Mukundupur