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A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.
The researchers examined the blood of two groups of healthy male donors in their 60s:
The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.
As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.
However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.
Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.
Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.
Read More: Who Can Donate Blood To Whom?
One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.
Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.
Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.
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Sitting under an air conditioner for prolonged hours could also give you high BP. (Photo credit: AI generated)
Contemporary office spaces have been designed to maximise comfort. Comfort includes central air conditioning, comfortable chairs, coffee dispensers, and beautiful interior design. Nonetheless, all these cool offices contribute greatly to the increase in blood pressure among unsuspecting employees. Many office workers spend about 8–10 hours indoors, thinking that comfort equates to good health. Sedentary lifestyles, stress at work, poor eating habits, and minimal movement are some of the factors resulting in increased levels of hypertension among young office-goers.
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In an interview with Health and Me, Dr Tushar Tayal, Associate Director, Internal Medicine, CK Birla Hospital, Gurugram, explained how extreme air conditioning at work can slowly weaken your heart and give you high blood pressure.
"Being constantly exposed to an air-conditioned environment may indirectly contribute to the rise in blood pressure levels. Extremely cold temperatures may prevent a person from moving around and sweating. People are less likely to go outside because of the difference in temperature between the interior and exterior environments. On top of that, dry air from air conditioners contributes to dehydration, particularly when people consume too much caffeine and too little water," Dr Tayal explained.
Although an office atmosphere may seem serene from the outside, the corporate environment is frequently linked with high mental stress. Pressure to meet targets, appraisals, fear of being laid off, lengthy meetings, and information overload lead to the body being continuously on guard. High levels of stress hormones, such as cortisol and adrenaline, can increase blood pressure. Employees often experience silent stress, which means that while they may not feel emotionally stressed, they suffer from physiological symptoms including headaches, exhaustion, irritability, and hypertension.
A sedentary lifestyle has proven to be one of the major contributors to high blood pressure among corporate employees who spend much of their time sitting while participating in meetings, watching presentations, or working on computers. Physical inactivity makes the heart less effective while causing issues such as obesity, diabetes, and hypertension. One may think that people who play sports for an hour every day face no risks associated with a sedentary lifestyle, but even then, sedentarism can harm a person. Office employees tend to underestimate the amount of physical activity they engage in at their workplace.
Dr Tayal said that the food culture in a corporate office plays a significant role in the development of high blood pressure as well. Numerous tea breaks, snacking on packaged foods with too much salt, takeaway meals, sweet drinks consumed in large amounts, and late suppers after overtime—all these aspects may affect cardiovascular health. Stress-related eating habits and improper food intake also play a role in metabolic disruptions. Consuming foods with excessive salt may be harmful.
The expert went on to explain that previously, hypertension used to be linked more with elderly individuals. Now, doctors have been noting instances of high blood pressure among young professionals in their mid-20s and 30s. Corporate workers might look healthy from the outside but often neglect signs such as poor sleep quality, fatigue, dizzy spells, or stress. Because there may be no visible signs of high blood pressure, many cases are discovered only through regular medical check-ups. Specialists advise that undiagnosed hypertension can result in serious diseases in the future, such as heart disease or stroke.
Modern companies have begun to be urged to reassess the idea of wellness in the office. Promoting physical activity breaks, standing meetings, drinking water, looking after mental health, choosing healthier foods at the company canteen, and getting screened for hypertension can aid in minimising the risks of this illness. Workers can start by implementing small changes, such as doing stretching exercises once an hour, walking around while on the phone, consuming less coffee, and measuring their blood pressure regularly.
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Individuals who experience tingling, numbness, and burning sensations in their hands and feet often disregard these early symptoms, especially after a long drive, extended standing, or sleeping. Many frequently take painkillers to ease their discomfort in the hope that their pain and other symptoms will quickly go away.
These types of persistent or recurrent symptoms, however, could be a signal of a nerve health issue such as peripheral neuropathy. Vitamin B12 is crucial for the nervous system, and its deficiency could be one of the potential causes.
Early detection of these symptoms and appropriate, timely medical advice can help facilitate immediate intervention. Addressing nutritional gaps under medical guidance may help support overall nerve health and reduce the risk of progression.
Neurotropic B-vitamins are essential for preserving the structure and function of nerves. A lack of these vitamins may present as:
Common Vitamin B12 deficiency signs include persistent fatigue, sensory disturbances, imbalance and neuropathic discomfort. Early detection supports timely intervention and may help prevent further nerve damage.
The right nutritional support plays a key role in preserving nerve function:
An appropriate and active approach to nerve care includes nutritional adjustments, metabolic regulation, and the right assistance to support symptoms.
Dietary Optimization: Encourage intake of foods rich in B-vitamins such as whole grains, dairy, eggs, legumes, and leafy vegetables. However, for those with restrictions, the diet alone might not be enough, especially in cases of established deficiency, malabsorption, or restricted diets.
Targeted Treatment: When guided by a healthcare professional, oral supplementation can be considered as part of a comprehensive plan.
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Dozens of food products, including chocolates, snack mixes, popcorn, chips, and nuts, have been recalled in the US over the risk of salmonella contamination.
The recall is due to a specific ingredient — milk powder supplied by California Dairies — used in several products and snacks, particularly in seasonings.
According to the Food and Drug Administration (FDA), the potentially tainted powdered milk and buttermilk were voluntarily recalled on April 20.
Ghirardelli Chocolate Powders:
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The FDA urges people who purchased the products to throw them away or return them for a refund.
A separate Salmonella recall impacting 12 flavors of the popular chocolate brand Spring & Mulberry was also recently announced by the FDA, but appeared to be linked to a date supplier. It wasn't immediately clear if there was any connection to the California Dairies recall.
Another is a public health alert issued by the US Department of Agriculture’s Food Safety and Inspection Service (FSIS) for headcheese over possible contamination with Listeria monocytogenes (Lm).
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As per the US Food and Drug Administration (FDA), Salmonella is a group of bacteria that can cause gastrointestinal illness and fever called salmonellosis. It can be spread by food handlers who do not wash their hands and/or the surfaces and tools they use between food preparation steps. It can also happen when people consume uncooked and raw food. Salmonella can also spread from animals to people.
The FDA notes that people who have direct contact with certain animals, including poultry and reptiles, can spread the bacteria from the animal to food if hand washing hygiene is not practiced.
Pets, too, could spread the bacteria within the home environment if they eat food contaminated with Salmonella.
Common symptoms of Salmonella include
Children younger than 5, adults 65 and older, and people with weakened immune systems are more likely to have severe illness.
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