A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.

What Did The Study Find?

The researchers examined the blood of two groups of healthy male donors in their 60s:

• One group had donated blood three times a year for 40 years.
• The other group had donated only about five times in total.

The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.

How Can Blood Donation Affect Stem Cells?

As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.

However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.

Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.

Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.

Read More: Who Can Donate Blood To Whom?

Limitations

One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.

Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.

Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.

Also Read: How Long After a Tattoo or Piercing Can I Donate Blood?

In 2022, there were almost 20 million new cases of cancer and 9.7 million cancer-related deaths worldwide, noted the National Cancer Institute (US). By 2050, it is predicted that the number of new cancer cases will rise to 33 million per year, with deaths rising to 18.2 million. While there are many reasons for cancer, a new comprehensive study by the World Health Organization (WHO) revealed that there are two major habits that are the leading cause of cancer.

As per WHO, more than 38% of cancer cases worldwide are linked to modifiable risk factors. The study is published in the journal Nature Medicine and it suggests that millions of diagnoses each year could be avoided through lifestyle changes, medical interventions, and environmental improvements.

WHO Study Says These 2 Major Habits Could Cause Cancer

Tobacco Use

As per the Association of Tobacco Use and Cancer Incidence, in India, the risk of any cancer with smoke and smokeless tobacco is 2.71 and 2.68, respectively. The study noted that risk of cancer due to tobacco use is consistent especially in India. Site-specific analysis showed higher risks of respiratory system cancers of 4.97 and head and neck cancers of 3.95.

As per several studies, including Cancer Research UK and National Institutes of Health (NIH), tobacco causes approximately 2.5 million cancer deaths globally, every year. This means, it accounts for 1 in every 4 global cancer death. It is also linked to 16 to 20 different types of cancer.

The WHO ranked it as the top reason for cancer, which is responsible for 15% of all global cancer cases. The impact is more in men, leading to 23% more new diagnoses.

Alcohol Use

The WHO study ranks it as the second most significant lifestyle factor that accounts for 700,000 new cases annually, leading to 3.2% of global cancer cases.

As per the National Cancer Institute (US), alcohol consumption is a significant, preventable cause of cancer, responsible for an estimated 741,300 to 750,000 new cancer cases worldwide in 2020. It is linked to cancers of the mouth, throat, esophagus, liver, colon, and breast. Even light-to-moderate drinking contributes, with about 185,100 cases annually tied to consuming two or fewer drinks per day.

What Are The Other Causes Of Cancer As Per WHO Study

Air pollution is a major cause of lung cancer, particularly in heavily polluted regions. In East Asia, for instance, around 15 per cent of lung cancer cases in women are linked to poor air quality. Experts say this underlines the urgent need for cleaner energy and stricter pollution controls.

Infections are another significant contributor, accounting for about 10 per cent of new cancer cases globally. High-risk strains of the human papillomavirus are the leading cause of cervical cancer, while stomach cancer is often linked to infections associated with unsafe water and poor sanitation.

Other important risk factors include high body mass index, lack of physical activity and excessive exposure to ultraviolet radiation, all of which continue to drive cancer rates across different populations.

The number of autistic women is same as the number of autistic men, but women know to hide it well, says research. A study published in the BMJ, found that while the rates of diagnosis for autistic is found among young boys and girls, rates are almost identical by the time they reach adulthood. However, these new findings have also shown that women are more likely to "mask" signs of autism in order to fit in. This is why their diagnosis is done far later.

What Did The Study Find Out?

This is the first major study to find such high levels of condition among women. Previously, diagnoses rates were four times higher among boys and men than females.

Specialists say the findings highlight the urgent need to move away from outdated stereotypes that still influence how autism is recognized and diagnosed.

The international study, led by researchers at the Karolinska Institutet in Sweden, examined autism diagnosis rates among people born in Sweden between 1985 and 2000. More than 2.7 million individuals were followed for up to 37 years, making it one of the most comprehensive studies of its kind.

By 2022, around 2.8 per cent of the population studied had been diagnosed with autism spectrum disorder. The data revealed a clear pattern. In early childhood, boys were far more likely than girls to receive an autism diagnosis. However, this gap steadily narrowed during adolescence.

By the time participants reached their late teens and early 20s, diagnosis rates among men and women were broadly similar. Researchers noted that the male to female ratio of autism diagnoses decreased over time to the point that it may no longer be distinguishable in adulthood.

A Catch-Up Effect in Adolescence

Dr Caroline Fyfe, lead author of the study from the University of Edinburgh, said autism has long been viewed as a condition that mainly affects males. While that pattern was still visible in children under 10, the picture changed rapidly during adolescence.

Read: Mattel Launches First-Ever Barbie With Autism

She explained that diagnoses among girls rose sharply in the teenage years, creating what researchers described as a female catch-up effect. By the age of 20, autism rates were almost equal between men and women. According to Dr Fyfe, this suggests late or missed diagnoses in females rather than a true biological difference between sexes.

Masking and Mental Health Misdiagnoses

Experts say one major reason for delayed diagnosis is masking. Girls and women are often more likely to imitate social behavior, maintain eye contact and suppress traits traditionally associated with autism. While this can help them fit in socially, it can also make their difficulties harder to identify in clinical settings.

Dr Judith Brown from the National Autistic Society said gender should never be a barrier to diagnosis or support. She noted that autistic women who are misdiagnosed often develop additional mental health challenges due to years without appropriate understanding or help.

She added that the exhaustion of constant masking can contribute to anxiety and depression, reinforcing the importance of recognizing autism earlier in girls.

Clinical Biases Under Scrutiny

Dr Steven Kapp, senior lecturer in psychology at the University of Portsmouth, said research has consistently shown that clinical biases play a role in under-recognizing autism in women and girls. He explained that subtler behaviors and social adaptation often lead clinicians to overlook autism in females.

A linked editorial written by a patient and advocate echoed these concerns, warning that autistic women are frequently labelled with mood or personality disorders while waiting for a correct diagnosis. As a result, many are forced to self-advocate simply to be recognized as autistic.

Experts say the findings should prompt changes in diagnostic approaches, ensuring that autistic girls and women are no longer left unseen.

Actor Claire Foy has revealed that a long, uncomfortable health struggle picked up while travelling ended up reshaping her relationship with caffeine. The Crown star, 41, said she gave up tea and coffee after discovering she had stomach parasites, an experience she described as “gross” and “absolutely rank.”

Foy shared the story during her appearance on The Table Manners Podcast with hosts Jessie and Lennie Ware on February 4, where the conversation moved from food to a period of unexplained weight loss and constant hunger.

“I kept losing weight, and I didn’t know what was going on,” she told the hosts. Despite eating regularly, she said she never felt full. “I was so hungry,” Foy recalled, adding that the situation left her confused and worried.

Diagnosis After Years of Symptoms

The actor explained that the cause was eventually traced back to stomach parasites she had picked up while travelling in Morocco. The diagnosis came after medical tests, including stool samples, which she candidly described as unpleasant but necessary.

According to Foy, doctors told her she had been carrying the parasites for around five years, a length of time she herself described as “quite a long time.” While she did not name the specific parasites, she shared one detail that stuck with her. “They travel as a pair, I got told by the doctor,” she said, reacting with visible disgust even years later.

Living with the condition took a toll on her body and routine. The ongoing symptoms pushed her to rethink how she approached treatment and daily habits, including what she consumed.

Read: 10 Signs You May Have A Parasite

Clair Foy Had Parasites For 5 Years: Why Caffeine Had to Go

It was during treatment that Foy made the decision to give up caffeine entirely. She explained that she wanted to avoid very strong antibiotics if possible and instead followed a strict diet alongside other treatments. “I basically had to go on this diet,” she said. “I didn’t want to take really hardcore antibiotics.”

As part of that process, caffeine was cut out. “I took all this gross stuff and part of that was giving up caffeine,” Foy told the hosts. At the time, it was a major shift. She admitted she had been a heavy caffeine consumer, drinking around 15 cups of tea a day along with two coffees she had carefully planned into her schedule.

A Habit That Never Came Back

Giving up caffeine was not easy, but once she did, Foy decided to stick with it. “Once you’ve given it up, it’s such a mission to give it up, that I was like, well, maybe I’ll just give it a go,” she said.

Now fully caffeine-free, she even brought her own tea bags to the podcast recording. The show is known for hosts and guests sharing food and drinks in the Ware family kitchen, making her preparation a small but telling detail of how seriously she takes the change.

Medical experts note that parasitic infections usually require medication to clear completely, often involving antiparasitic drugs and sometimes antibiotics or antifungals. In many cases, a combination of treatments is needed.