Regular Blood Donation May Influence Cancer Risk

Updated Mar 12, 2025 | 11:00 PM IST

SummaryAs and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow.
Can blood donation reduce cancer risk?

Credits: Canva

A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.

What Did The Study Find?

The researchers examined the blood of two groups of healthy male donors in their 60s:

  • One group had donated blood three times a year for 40 years.
  • The other group had donated only about five times in total.

The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.

How Can Blood Donation Affect Stem Cells?

As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.

However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.

Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.

Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.

Read More: Who Can Donate Blood To Whom?

Limitations

One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.

Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.

Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.

Also Read: How Long After a Tattoo or Piercing Can I Donate Blood?

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Why Clean Surroundings Are The First Line Of Defense Against Malaria

Updated Apr 26, 2026 | 10:00 PM IST

SummaryTreating a patient comes later. Stopping the mosquito from breeding is the foundation of the battle against malaria, and that depends on everyday cleanliness by everybody residing in each lane and building.
Why Clean Surroundings Are The First Line Of Defense Against Malaria

Credit: Canva

India is surely winning the battle against malaria. However, the disease is still around. Medicines and nets help a lot, but doctors point to something else. They say the real cure starts before you even get sick. It all comes down to keeping your local area totally clean.

This fever only spreads through female Anopheles mosquitoes. They do not need big ponds to multiply. A little dirty water trapped inside an old tyre, a thrown-away plastic cup, or a coconut shell is all they need. That is where the cycle of malaria starts. Within days, larvae turn into mosquitoes, and the infection begins to move through nearby homes. This is why many doctors put it plainly. Treating a patient comes later. Stopping the mosquito from breeding is the foundation of the battle against malaria, and that depends on everyday cleanliness by everybody residing in each lane and building.

The official health data brings major relief. Malaria is finally losing its grip. Fresh WHO reports prove this fact. In 2017, India struggled with nearly 64 lakh cases. But the figures show a steep fall in the number of cases by 2023. The total patient count stood at just 20 lakh. We are looking at a clear 69 percent drop in a very short time. Seeing this huge improvement, the WHO took India off its critical 'High Burden to High Impact' list in 2024.

Data released by the government of India tells a similar story. Figures from the National Center for Vector-Borne Diseases Control under the Union Health Ministry show a decline in the number of deaths by more than 78 percent between 2015 and 2023. The target now is clear. The government has set a very clear target. They want malaria cases to hit zero by 2027. After that, the final goal is to wipe out this disease from the entire country by 2030.

We are winning this fight, but the danger is still far from over. Cover your water tanks properly. Clean the open drains. Do not let rainwater collect near your house. These small daily habits easily stop the disease from spreading.

However, the health department alone cannot achieve this massive target. Fogging and spraying of chemicals done by municipal bodies only kill adult mosquitoes that are already flying. The fight is local. If water tanks are shut tight, drains are not clogged, and garbage isn’t left to collect rainwater, the danger drops quickly.

When a society maintains clean surroundings, it naturally destroys the breeding grounds for mosquitoes. If the mosquitoes cannot breed, the chain of infection breaks automatically. As India moves closer to its 2030 malaria-free goal, keeping our streets, parks, and homes clean is no longer just a civic duty. It is our absolute first line of medical defense against a deadly disease.

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Oncologist Answers: Can Heating Food In Black Plastic Bowls Give You Cancer?

Updated Apr 26, 2026 | 01:00 PM IST

SummaryBlack plastic containers have 'carbon black,' which, upon heating, releases toxic, cancer-causing chemicals.
black containers

Take-out food often comes in black plastic containers, but these are far from safe for your health. (Photo credit: iStock)

Plastic containers have been discouraged for a long time now, especially for heating food or storing hot food. Studies have associated this habit with a heightened risk of cancer, but now an expert has specifically spoken about black plastic containers and what makes them worse for you. According to Dr Rakesh Kumar Sharma, Senior Consultant Medical Oncologist at M | O | C Cancer Care & Research Centre, Gurugram, cooking or heating food in black containers could be very harmful to your body. Read on to find out how.

Dr Sharma, in an interview with Health and Me, said that cooking food in black plastic receptacles could lead to greater amounts of certain chemicals making their way into your body; however, there currently exists no scientific evidence confirming that this daily activity increases your risk of cancer.

Why is black plastic worse than others?

Dr Sharma explained that black takeaway containers usually consist of recycled plastics, such as e-waste, and can contain flame retardants, BPA, phthalates, etc. When heated in contact with food, especially if the food is hot, fatty, or acidic, more chemicals could potentially make their way into the food from the container. In this way, it may, over time, heighten your risk of developing a malignant tumour.

Black containers are coloured using carbon black, which is included in Group 2B of possible human carcinogens according to IARC, as shown in both animal and limited human research. Moreover, recycled black plastics could contain polycyclic aromatic hydrocarbons and decaBDE, which have shown carcinogenic effects in experiments. This makes black plastic containers worse than other coloured counterparts. Yet, heating food in a plastic container of any colour is not deemed safe.

Do studies verify the side effects of heating food in plastic containers?

Experimental studies conducted in laboratories on microwaveable plastic receptacles reveal the migration of tens of chemicals and millions of microplastics per litre of the food simulant. However, a recent study in 2024 reported that containers labelled as microwave-safe in Korea adhered to contemporary safety standards for these levels, and total exposure fell within safe limits.

Leading cancer associations have confirmed that the usage of plastic packaging, even in microwave applications, has not been linked with increased cancer risks in humans, although there is ongoing research in areas such as black plastics. However, precautionary measures are suggested by experts as a better strategy due to the difficulties of directly studying long-term, low-level exposure to chemical compounds.

How to reduce cancer risk?

When it comes to reducing cancer risk, most doctors recommend quitting smoking and limiting alcohol intake. However, Dr Sharma listed some basic kitchen and eating habits that may come to your rescue:

  1. Avoid cooking food in black plastic packaging, particularly if the food is oily or acidic.
  2. Move hot food into glass, ceramic, or stainless steel containers for reheating.
  3. Only use microwave-safe containers and discard any broken plastic containers.

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Decoding Depression In Men: The Emotion Behind The Silence

Updated Apr 26, 2026 | 05:00 PM IST

SummaryOne of the key barriers in identifying depression in men is the way emotional awareness is shaped from an early age. Many men are conditioned to respond to discomfort through action rather than reflection.
Decoding Depression in Men: The Emotion Behind The Silence

Credit: iStock

Depression in men often does not look like the depression we all know about. It is never visible sadness or a verbal expression of emotional pain. The emotional dish is missing from the life menu of a man.

It hides behind productivity, irritability, exhaustion, or strong discipline. This masking makes it the most underdiagnosed mental health concern, frequently misread as stress, burnout, or simply personality traits.

One of the key barriers in identifying depression in men is the way emotional awareness is shaped from an early age. Many men are conditioned to respond to discomfort through action rather than reflection.

The moment something feels overwhelming, the instinct is not to sit with the feeling but to fix it, outperform it, or suppress it through movement—work, exercise, or distraction.

While this can provide short-term relief, it often delays emotional processing and deepens internal distress over time.

Clinically, this disconnect is often linked to alexithymia—a difficulty in identifying and articulating emotions.

The emotional signal is present, but it does not translate easily into words. Instead of “I am sad” or “I feel afraid,” the experience gets reduced to “I am tired” or “I am stressed.”

This limited emotional vocabulary can significantly affect help-seeking behavior like therapy and counselling, as the man does not recognize the depth or nature of what they are experiencing.

Depression In Men: Poor Physical Health

From a health perspective, unresolved emotional stress is not limited to the mind. It reflects in the body.

Chronic fatigue, sleep disturbances, headaches, digestive issues, and muscle tension are some of the symptoms seen.

Men who are very aware tend to see general physicians and not go to mental health professionals, treating physical symptoms while the psychological root remains unattended to.

Another way is externalized emotion. Irritability, anger outbursts, or risk-taking behaviour are often socially accepted expressions of underlying emotional pain.

A man working excessively, exercising compulsively, or withdrawing socially may, in fact, be coping with grief, loneliness, or anxiety, which are socially normal.

Our culture around masculinity complicates diagnosis even more. Strength is seen with emotional control, and vulnerability is seen as weakness.

Most men do not seek psychological support until symptoms become severe or functionally impairing. They struggle to express their internal state, reinforcing the cycle of silence.

Depression In Men: Physiological Indicators

Understanding depression in men requires shifting the lens from visible sadness to behavioral and physiological indicators.

It requires mental health practitioners and caregivers to look beyond surface functionality and recognise that high performance can coexist with deep emotional distress.

Early intervention is very important. Creating environments where emotional language is normalised without judgement or immediate problem-solving can significantly improve the situation. When men are given consistent permission to articulate internal states without fear of stigma, the gap between emotional experience and expression begins to close.

“Expressing your feelings should lead to a deeper connection, not conflict. It should invite empathy, not ego-driven reactions. It should bring relief, not retaliation or emotional punishment. If sharing your pain feels unsafe or punished, you are not in a healthy relationship—you are in an emotional environment where fear has replaced trust.”

Depression in men is not a lack of feeling, but a lack of translation. True healing begins when that translation is finally allowed to happen.

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