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A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.
The researchers examined the blood of two groups of healthy male donors in their 60s:
The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.
As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.
However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.
Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.
Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.
Read More: Who Can Donate Blood To Whom?
One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.
Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.
Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.
Also Read: How Long After a Tattoo or Piercing Can I Donate Blood?
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People think of menopause as just hot flashes and irregular periods, but menopause is more than that.
Perimenopause and menopause can bring a host of emotional and cognitive shifts for many women, including mood swings, anxiety, easily irritated, trouble sleeping, or having what some refer to as “brain fog.”
Perimenopause is the period leading up to menopause that can last anywhere from two to eight years. This is when hormonal changes take place, especially a drop in estrogen.
These hormonal changes also impact neurotransmitters like serotonin and dopamine that are essential for mood, memory, sleep and emotional wellness.
Consequently, a woman can suffer from forgetfulness, lack of concentration, mental tiredness, low energy levels, dry skin, loss of libido and less productivity.
Also read: Shamita Shetty’s Endometriosis Diagnosis Sparks Concerns About Risks Of Delayed Detection
Brain fog can be a frustrating and overwhelming experience during menopause, particularly if a woman is juggling her career, family, ageing parents and personal obligations.
Many women suffer from anxiety symptoms, even if they have no mental health background. Hormonal changes, poor sleep and stress can exacerbate these symptoms.
But not all symptoms are due to the menopause or "normal ageing". Thyroid disorders, vitamin deficiencies, depression and other medical problems can have similar symptoms.
Therefore, if symptoms start to impact life, work, relationships or emotional wellbeing, it is important to seek medical advice and have a proper health check-up.
Management is often comprehensive, and may involve lifestyle modifications. Regular exercise, balanced nutrition, stress management and healthy sleep patterns.
In a few instances, you may additionally be suggested to take Menopausal Hormone Therapy (MHT). As more research is done and preparations of lower doses and greater safety, earlier misconceptions about hormone therapy are gradually decreasing.
Medically, women can make a difference in their quality of lives and manage menopause with greater physical, mental and emotional wellness with early recognition and timely intervention.
By Dr. Nidhi Sharma Chauhan, Gynaecologist, Saifee Hospital
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Everyone knows that using sunscreen is one of the most important steps for protecting the skin from harmful sun rays, but dermatologists explain that it isn't the only thing you should do to keep your skin healthy. Other daily routines are also important for minimizing sun damage and maintaining healthy skin over time.
Skin is a protective barrier for the body but constant exposure to the sun, pollution, heat and unhealthy lifestyle habits can make this barrier vulnerable.
Once the skin barrier is damaged, the skin is more susceptible to tanning, pigmentation, dryness, sun ageing and other sun damage.
Using a moisturiser every day is a very simple, yet effective habit. A good moisturiser is one that doesn't contain any scents and will support the barrier function of the skin, thereby preventing unwanted water loss from the skin.
Wet and plump skin is resistant to the environment and sun's rays.
Also read: Add These 8 Foods To Your Diet For Batter Hair, Skin And Nails
Antioxidants are also a best practice for dermatologists. Antioxidants prevent the damage to skin cells by free radicals created by UV exposure, pollution etc.
This protection can help minimize issues like hyperpigmentation, uneven skin tone and premature ageing. Consuming foods that contain antioxidants (such as fruits, vegetables and nuts) can help keep skin healthy on the inside.
Next, hydration is crucial. It's important to keep drinking enough water all day long to keep the skin supple and to allow the skin to repair itself. Moisture also contributes to skin's healing from environmental stress.
Sun protection is also of great importance. Wearing hats or caps, using umbrellas, and wearing clothing that protects against the sun's rays can minimize direct exposure to the sun.
All these are simple actions that serve as a physical barrier and prevent sunburn and long term damage to the skin, particularly between 10 a.m. and 4 p.m. These simple steps provide a physical barrier and reduce the risk of sunburn and chronic skin damage, particularly in the peak hours of 10 a.m. to 4 p.m.
Also read: Dermatologist Reveals What To Add And Remove From Skincare Routine For Season Change
Another focus has been on the connection between gut health and healthy skin, as experts recognize how crucial the role of the gut is in maintaining healthy skin.
Probiotics can potentially improve the gut-skin axis and aid in the healing process and alleviate inflammation in the body. The better the gut environment, the better the skin will be able to recover and the less the exposure to the sun will age the skin.
Some people can use collagen supplements as an added benefit. Collagen is involved in supporting the dermis, the skin's structural component. Keeping collagen high can help promote skin repair and healing mechanisms.
Doctors say while sunscreen is important, long-term skin protection can be achieved through a variety of healthy habits, proper nutrition, hydration and physical sun protection measures, which must be followed daily.
Dr. Pravin Banodkar Senior Consultant Dermatologist Saifee Hospital
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We tend to think of our eyes as easy – they just "see", and we go about our day. But the fact is, your eyes are adapting a lot, focusing and straining all the time, far more than you realize. Many of these moments are utterly unremarkable, but they build up gradually into a tiredness, a dryness and a long-term strain.
We see many people who are shocked to find out how hard their eyes had been working long before any symptoms appeared. Here are six common situations that deserve a whole lot more attention – and care – from your eyes.
Having a quick glance at notifications before even leaving bed requires your eyes to adjust to a small, bright screen in the dark. This quick change puts a load on the eye muscles and can make them tire before your day has really started.
Working, studying, and hopping from meeting to meeting: extended hours in front of the screen drastically lower your usual blink rate. Less blinking equals less lubrication, which is why so many people are dry, irritated and have blurry vision by the afternoon.
Night driving is one of the most challenging visual jobs humans undertake, given low light, incoming headlights and the need to constantly change focus between the road, mirrors and dashboard. Your eyes are working tirelessly to shift between bright and dim situations in fractions of a second.
Night driving is one of the most challenging visual jobs humans undertake, given low light, incoming headlights and the need to constantly change focus between the road, mirrors and dashboard. Your eyes are working tirelessly to shift between bright and dim situations in fractions of a second.
Also read: El Salvador Becomes First Country In Central America To Eliminate Trachoma: WHO
Poorly lit restaurant menus, pharmaceutical labels, or the small text on a contract all demand that you focus hard at close range, frequently in less-than-ideal illumination. As we get older, this type of near-focus strain is very common since our natural ability to focus declines.
Glancing from your laptop to your phone to a television and back again, it makes your eyes refocus at multiple distances. It is easier, but this continual flipping is more tiring than looking at one screen for the same period of time.
Your eyes work hard to adjust while you move from a dim room into harsh daylight — or vice versa. Over time, repeated exposure to glare without the correct protection (such as sunglasses) can add unneeded strain.
None of these moments feel dramatic on their own, but together, they represent a significant daily workload for your eyes. The good news is that habits such as the 20-20-20 rule, correct lighting, regular blinking and eye check-ups can go a long way in reducing this concealed tension. We believe that awareness is the beginning of healthy eyesight.
If you are suffering frequent eye strain, dryness or fuzzy vision, it may be time to schedule a full eye exam. Your eyes work harder than you realize – let’s give them the attention they deserve.
Dr Mandeep Singh Basu, Ayurvedic Eyecare Expert, Dr Basu Eye Care Centre
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