Credits: Canva
A recent study suggests that people who donate blood regularly may have genetic changes in their blood that could in fact reduce the risk of developing cancer. It is conducted by the researchers at the Francis Crick Institute, and the study has now provided new insights into how and why blood cancers develop. The study is published in the journal Blood and was conducted by the scientists from Heidelberg and the German Red Cross blood donation center. There is yet a need for further research to confirm these findings.
The researchers examined the blood of two groups of healthy male donors in their 60s:
The goal was to analyze genetic mutations in their blood and assess whether frequent donation had any impact on their genetic makeup.
As and when people age, their blood and other cells naturally develop mutations and some of them can also increase the risk of cancer. When anyone donates blood, his or her body compensates by producing new blood cells, which can influence the genetic diversity of stem cells in the bone marrow. The study also found that both groups had a similar number of mutations. For instance the frequent donors had 217 mutations, while the irregular donors had 212 mutations.
However, the nature of these mutations differed. In the frequent donors, 50% of the mutations were of a type not associated with a high risk of blood cancers, compared to only 30% in the irregular donors.
Further laboratory analysis showed that these specific mutations behaved differently from those linked to leukemia, a type of blood cancer. When human blood stem cells with these mutations were injected into mice, they were found to be highly effective at producing red blood cells, which is considered a positive outcome.
Dr. Hector Huerga Encabo, one of the study authors, emphasized that these mutations do not indicate an increased risk of leukemia. The findings suggest that regular blood donation may influence how stem cells evolve, but whether this translates into a lower cancer risk remains uncertain.
Read More: Who Can Donate Blood To Whom?
One notable disadvantage is the "healthy-donor effect"—because blood donors are often healthier than the general population, their lower cancer risk could be unrelated to blood donation.
Dominique Bonnet, senior researcher and head of a stem-cell laboratory at the Francis Crick Institute, stressed the need for larger studies with female volunteers to confirm the findings.
Despite ongoing research into potential health benefits for donors, the primary goal of blood donation remains saving lives. NHS Blood and Transplant emphasized that while the study is interesting, further research is required to draw firm conclusions. The organization also noted that blood supplies are currently critically low and encouraged eligible individuals to donate.
Also Read: How Long After a Tattoo or Piercing Can I Donate Blood?
Credit: AI
Skin breakouts are often common occurrences during the monsoon season, but not all outbreaks of bumps that occur during this period are traditional cases of acne.
The combination of humidity along with sweat and sebum production makes the skin susceptible to different skin conditions, making it easy to mistake fungal acne for a regular one.
While acne and fungal acne may appear almost identical, the factors that trigger them are not the same. Identifying the right condition early makes it easier to choose the most appropriate treatment and maintain healthier skin in the long run.
It is quite common to experience frequent breakouts during monsoon season. This usually happens due to the accumulation of humid conditions, sweat, and increased oil production.
When sweat mixes with sebum, dead skin cells and skincare products, pores may become clogged, which eventually results in acne. At the same time, the environment also supports the growth of Malassezia, a yeast that naturally lives on the skin.
When it grows excessively, it can trigger fungal acne, medically known as Malassezia folliculitis. Since both conditions tend to flare up during the rainy season, they are frequently confused with one another.
Also read: Besides Sunscreen, What Everyday Habits Can Help Reduce Sun Exposure And Skin Damage?
There are several indications which one may use to differentiate between normal acne and fungal acne. Regular acne mostly develops as a combination of blackheads, whiteheads, inflamed pimples, and sometimes painful cysts.
On the other hand, fungal acne presents itself in the form of tiny bumps that usually appear itchy and develop in clusters. These bumps commonly occur on the forehead, chest, shoulders and upper back, especially in areas where sweat tends to collect.
Since regular acne and fungal acne occur due to different reasons, they also require different treatment approaches. Although proper skin care can help in reducing the possibilities of outbreaks, it does not entirely prevent breakouts.
Over-the-counter acne products are usually intended to unclog the pores and control the growth of bacteria causing acne; however, they do not work on fungal infections. In fact, in some cases, using the wrong products can even worsen irritation or allow the breakouts to persist.
Therefore, always consult a dermatologist for targeted skin issues, particularly when acne scars are also a concern. In such situations, many experts may suggest modern treatments such as Harmony XL Pro for personalised results.
This multi-application platform combines numerous energy-based technologies to address specific acne-related concerns and is also used in a variety of aesthetic procedures such as acne-scar removal and overall skin rejuvenation.
A minimal skincare routine can go a long way during the monsoon. Always start with a gentle cleansing after excessive sweating. Choose non-comedogenic moisturisers and make sure not to apply multiple oily or occlusive products that could result in clogged pores.
If you develop a breakout, do not pick or squeeze the acne, as doing so can increase inflammation and the risk of scarring.
In the end, recognising whether a breakout is regular acne or a fungal one is the first step towards appropriate treatment. Although both conditions become more common during humid weather, they are not managed in the same way.
Paying attention to symptoms such as itching, the pattern of the bumps and how the skin responds to treatment can make a meaningful difference.
By Dr. Anwesha Poddar, Dermatologist, Dr. Anwesha Poddar Skin, Laser & Hair Clinic
Credit: AI
People think of menopause as just hot flashes and irregular periods, but menopause is more than that.
Perimenopause and menopause can bring a host of emotional and cognitive shifts for many women, including mood swings, anxiety, easily irritated, trouble sleeping, or having what some refer to as “brain fog.”
Perimenopause is the period leading up to menopause that can last anywhere from two to eight years. This is when hormonal changes take place, especially a drop in estrogen.
These hormonal changes also impact neurotransmitters like serotonin and dopamine that are essential for mood, memory, sleep and emotional wellness.
Consequently, a woman can suffer from forgetfulness, lack of concentration, mental tiredness, low energy levels, dry skin, loss of libido and less productivity.
Also read: Shamita Shetty’s Endometriosis Diagnosis Sparks Concerns About Risks Of Delayed Detection
Brain fog can be a frustrating and overwhelming experience during menopause, particularly if a woman is juggling her career, family, ageing parents and personal obligations.
Many women suffer from anxiety symptoms, even if they have no mental health background. Hormonal changes, poor sleep and stress can exacerbate these symptoms.
But not all symptoms are due to the menopause or "normal ageing". Thyroid disorders, vitamin deficiencies, depression and other medical problems can have similar symptoms.
Therefore, if symptoms start to impact life, work, relationships or emotional wellbeing, it is important to seek medical advice and have a proper health check-up.
Management is often comprehensive, and may involve lifestyle modifications. Regular exercise, balanced nutrition, stress management and healthy sleep patterns.
In a few instances, you may additionally be suggested to take Menopausal Hormone Therapy (MHT). As more research is done and preparations of lower doses and greater safety, earlier misconceptions about hormone therapy are gradually decreasing.
Medically, women can make a difference in their quality of lives and manage menopause with greater physical, mental and emotional wellness with early recognition and timely intervention.
By Dr. Nidhi Sharma Chauhan, Gynaecologist, Saifee Hospital
Credit: AI
Everyone knows that using sunscreen is one of the most important steps for protecting the skin from harmful sun rays, but dermatologists explain that it isn't the only thing you should do to keep your skin healthy. Other daily routines are also important for minimizing sun damage and maintaining healthy skin over time.
Skin is a protective barrier for the body but constant exposure to the sun, pollution, heat and unhealthy lifestyle habits can make this barrier vulnerable.
Once the skin barrier is damaged, the skin is more susceptible to tanning, pigmentation, dryness, sun ageing and other sun damage.
Using a moisturiser every day is a very simple, yet effective habit. A good moisturiser is one that doesn't contain any scents and will support the barrier function of the skin, thereby preventing unwanted water loss from the skin.
Wet and plump skin is resistant to the environment and sun's rays.
Also read: Add These 8 Foods To Your Diet For Batter Hair, Skin And Nails
Antioxidants are also a best practice for dermatologists. Antioxidants prevent the damage to skin cells by free radicals created by UV exposure, pollution etc.
This protection can help minimize issues like hyperpigmentation, uneven skin tone and premature ageing. Consuming foods that contain antioxidants (such as fruits, vegetables and nuts) can help keep skin healthy on the inside.
Next, hydration is crucial. It's important to keep drinking enough water all day long to keep the skin supple and to allow the skin to repair itself. Moisture also contributes to skin's healing from environmental stress.
Sun protection is also of great importance. Wearing hats or caps, using umbrellas, and wearing clothing that protects against the sun's rays can minimize direct exposure to the sun.
All these are simple actions that serve as a physical barrier and prevent sunburn and long term damage to the skin, particularly between 10 a.m. and 4 p.m. These simple steps provide a physical barrier and reduce the risk of sunburn and chronic skin damage, particularly in the peak hours of 10 a.m. to 4 p.m.
Also read: Dermatologist Reveals What To Add And Remove From Skincare Routine For Season Change
Another focus has been on the connection between gut health and healthy skin, as experts recognize how crucial the role of the gut is in maintaining healthy skin.
Probiotics can potentially improve the gut-skin axis and aid in the healing process and alleviate inflammation in the body. The better the gut environment, the better the skin will be able to recover and the less the exposure to the sun will age the skin.
Some people can use collagen supplements as an added benefit. Collagen is involved in supporting the dermis, the skin's structural component. Keeping collagen high can help promote skin repair and healing mechanisms.
Doctors say while sunscreen is important, long-term skin protection can be achieved through a variety of healthy habits, proper nutrition, hydration and physical sun protection measures, which must be followed daily.
Dr. Pravin Banodkar Senior Consultant Dermatologist Saifee Hospital
© 2024 Bennett, Coleman & Company Limited