For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

• Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
• Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
• Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
• Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

As a strong wave of “superflu” and other seasonal infections moves through the country, large numbers of people have fallen ill this winter. The rise has been serious enough for some NHS officials to advise anyone with symptoms to wear a mask. Newly released data shows how quickly the situation has worsened, with flu admissions jumping by 55 percent in a single week.

This sharp climb has pushed the NHS into what leaders describe as a “worst case scenario” for December. As per The Independent, over the past week, hospitals saw an average of 2,660 daily admissions for flu, the highest figure ever recorded at this point in the year. With so many people under the weather, many are trying to work out which pain reliever offers better comfort. An expert previously spoke to the Mirror on this exact point.

Superflu Cases Rise In UK

Figures released today highlight the severity of the situation, with flu hospitalisations having surged by more than half (55%) in just one week. This massive increase has officially plunged the NHS into a "worst case scenario" situation for the month of December. Last week, an average of 2,660 patients per day were admitted to hospital beds with flu, marking the highest number ever recorded for this time of year.

Superflu Cases: What To Take Paracetamol Or Ibuprofen?

With so many people falling poorly, it can be helpful to know which medicine is best to take. Thankfully an expert previously spoke to the Mirror about ibuprofen and paracetamol. Abbas Kanani, the superintendent pharmacist at Chemist Click, said: "Paracetamol is probably more effective at bringing down temperature, so it's almost like a double-whammy, you get rid of your headache and bring your temperature down. "But if you feel that you have more body aches, that's your main symptom, then ibuprofen is probably slightly better as it's an anti-inflammatory."

However, he cautioned users to be mindful of potential allergies to ibuprofen, which belongs to a specific class of drugs.

He also revealed that many people are unaware that they can actually take both medicines together when feeling particularly unwell. "If you feel that one isn't enough you can take ibuprofen as well as paracetamol, you can take them together. A lot of people don't know that it's not one or the other, you can put them together as they work in different ways."

While these two medications can alleviate aches, pains and fevers, as well as mild cold and flu symptoms, Abbas notes that they won't be particularly effective for those struggling with coughs and nasal congestion.

To address these specific symptoms, you'd need to utilise cold and flu products instead.

Choosing Medicine Based on Your Symptoms

Many people assume one medicine works better for all flu complaints, but the expert’s guidance shows that the right choice depends on what you’re feeling. Fever and headache respond more readily to paracetamol, while body aches and inflammation may ease faster with ibuprofen. For coughs or blocked sinuses, cold-and-flu formulas are needed because standard pain relievers do not target those issues.

Public forums often turn into places where people share worries they hesitate to bring up with a doctor. Reddit, especially, saw a surge of unusual yet genuinely important questions about sexually transmitted infections this year in 2025. A large number of these posts came from young adults who felt unsure about new symptoms, confused about how infections spread or overwhelmed by the flood of sexual-health content circulating online.

The ten questions below may seem odd at first glance, but each one raises a medically sensible point. Together, they show how gaps in sexual-health awareness still shape the way people talk about intimacy and illness on the internet.

What Is An STI?

STI refers to a Sexually Transmitted Infection. It is an infection passed through sexual activity such as oral, vaginal or anal contact, and in some cases through non-sexual routes such as blood exposure or mother-to-child transmission.

These infections can be caused by bacteria, viruses or parasites. Some lead to clear symptoms while others remain silent, but untreated cases can result in serious health problems. When an STI begins to cause notable medical issues, it is often described as a Sexually Transmitted Disease (STD).

Top 10 Weird But Medically Valid STI Questions People Asked On Reddit

“Is it possible to get an STI if both people are virgins?”

One user who had only engaged in oral and anal sex with another virgin noticed marks on their legs and wondered if infections could be “passed down by parents.” The spots disappeared on their own, likely due to shaving irritation, yet the question reveals a common misconception. STIs cannot be inherited genetically. They require actual transmission through sexual contact, blood or childbirth.

“Can kissing, a blowjob or rimming spread an STI?”

This question came from someone who had watched too many alarming clips about PrEP and safe sex on social media. They became so uneasy that they avoided going on dates until they understood the risks. Some infections can spread through oral sex and deep kissing, though the degree of risk varies. Their fear felt intense, but the doubt itself was completely reasonable.

“Has anyone in Sri Lanka even had an STI?”

A user in a regional subreddit asked whether STIs even “exist here” because no one talked about them openly. The framing sounded odd, but it reflected the silence that still surrounds sexual health in many places. STIs appear everywhere, though in some communities the subject is rarely discussed.

“What is the real STI risk from a glory hole?”

One of the year’s most unusual but earnest threads came from someone trying to understand whether anonymous sexual setups increase risk. They asked about skin-to-skin contact, bodily fluids and the impact of poor visibility. Though the question seemed strange, experts often point out that uncertainty about partners and surroundings can raise the chance of exposure.

“For people who use glory holes, aren’t you worried about getting an STI?”

Another thread took a more confrontational tone, suggesting that anyone who uses a glory hole “either already has an STD or doesn’t care.” Replies pushed back, saying that anonymity has many motives and that what truly matters is the use of protection and clarity about risk, not assumptions about a person’s character.

“Would I break up with a new partner if they gave me an STI?”

This question was framed like a moral dilemma, but the situation involved real medical timing. A woman had contracted an STI from a partner who had tested too early for the infection to show up on his results. One commenter suggested that the timing hinted at sexual activity very close to the start of their relationship. The discussion blended relationship boundaries with the science of incubation periods.

“I have every symptom under the sun. Is this an STI?”

A worried user described swollen tonsils, tiredness, muscle twitching, stomach cramps, cracking joints, night sweats and more. None of this lined up with any single STI, yet their panic was sincere. The thread showed how anxiety can turn normal bodily sensations into something that feels catastrophic.

“Could I have an STD from giving oral once?”

A person who had their first sexual experience by giving oral sex to an AFAB partner developed painful cracks on their genitals a few days later, even though there was no genital contact. They feared they had caught an infection. While genital cracks from oral contact alone are unlikely, some infections can move through oral-genital routes. Their confusion made sense even if the symptoms did not match the exposure.

“Are these rashes from sex or something else entirely?”

Several users described bumps, redness and irritation, convinced they must have an STI. Many replies explained that chafing, sweat, allergic reactions or grooming habits can look similar to infection symptoms.

“My symptoms came weeks later. Could it still be an STI?”

Some posters were puzzled when new bodily changes appeared long after a sexual encounter. They mentioned stomach issues, headaches or tiredness. While certain infections do have incubation windows, many unrelated issues can appear around the same time, which can lead people to make the wrong connection.

These questions may sound strange, but nearly all came from people trying to understand their bodies and risks. They also show how much sexual-health education remains incomplete. Proper testing, routine medical visits and clear conversations with professionals are still far more dependable than guessing through anonymous internet threads.

The World Health Organization (WHO) has reaffirmed that childhood vaccines do not cause autism spectrum disorders (ASD). This follows a fresh review by the WHO’s Global Advisory Committee on Vaccine Safety (GACVS), which examined 31 major studies published between January 2010 and August 2025. Last month, the US Centers for Disease Control and Prevention (CDC) adjusted its website wording, which some argued weakened its earlier, science-backed position that vaccines are not linked to autism. The WHO has now made its stance clear.

Years of research consistently show no causal relationship between vaccinations and autism or other developmental conditions. Robert F. Kennedy Jr., who has long promoted anti-vaccine views, has repeatedly claimed vaccines contribute to autism, despite evidence to the contrary. WHO Director-General Tedros Adhanom Ghebreyesus clarified in a Geneva press conference that vaccines do not cause autism.

WHO Rejects Claims Of Link Between Vaccines And Autism

“Today, WHO is releasing a new analysis by the Global Advisory Committee on Vaccine Safety, which concludes, based on all available evidence, that vaccines are not linked to autism,” said Tedros, as per the official WHO report. The committee reviewed 31 studies conducted across multiple countries over 15 years, looking at vaccines containing thiomersal—a preservative used to prevent bacterial and fungal growth in multi-dose vials—and aluminium adjuvants.

“The review found no evidence connecting vaccines, including those with aluminium or thiomersal, to autism,” Tedros added. “This is the fourth review of its kind, following similar evaluations in 2002, 2004, and 2012, all of which reached the same conclusion: vaccines do not cause autism. Like any medical product, vaccines can have side effects, which WHO monitors carefully, but autism is not one of them.”

What Is Autism Spectrum Disorder?

ASD usually refers to Autism Spectrum Disorder, a developmental condition that affects communication, social skills, and behavior, with a wide range of symptoms. It can also mean Atrial Septal Defect, a congenital heart condition characterized by a hole in the upper chambers of the heart. Context is important: the first is neurological, the second cardiac, according to the CDC.

RFK Jr Blames Vaccines For Causing Autism

Health And Me has previously reported that Robert F. Kennedy Jr., has long claimed that vaccines are responsible for autism. He has cited the rising autism diagnoses over recent decades—from about 1 in 150 children in 2000 to roughly 1 in 36 today—as evidence of vaccine harm. However, multiple studies have debunked this, showing that increased awareness, better screening, and broader diagnostic definitions that include milder forms of autism largely explain the rise. Kennedy’s assertions have been widely criticized by health authorities and autism advocacy groups.

According to the CDC, about half of parents surveyed who have autistic children believe that vaccines may have contributed to their child’s autism. This statistic comes from a 2006 survey published in the Journal of Developmental and Behavioral Pediatrics. The CDC explains that these vaccines are typically those administered within the first six months of life—such as Diphtheria, Tetanus, and Pertussis (DTaP), Hepatitis B (HepB), Haemophilus influenzae type B (Hib), inactivated Poliovirus (IPV), and Pneumococcal conjugate (PCV)—as well as one given at or after the child’s first birthday, the Measles, Mumps, and Rubella (MMR) vaccine.

No Link Between Vaccine And Autism

The supposed connection between the measles, mumps, and rubella (MMR) vaccine and autism originated from a flawed 1998 study, later retracted for using falsified data. Its findings were never replicated and have been thoroughly refuted by extensive research. “The study was shown to be fraudulent and withdrawn, but the notion it created has persisted,” said Tedros.

Kennedy has a long record of promoting questionable claims, which have become central to his “Make America Healthy Again” campaign, a notable element of President Trump’s broader Make America Great Again coalition. The recent CDC website changes sparked concern and alarm among career scientists and public health experts, including those within the agency, who have spent years combating misinformation.