For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

• Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
• Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
• Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
• Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

Changes in stride like a slower walking pace, fewer steps or a change in the way your arms move may be considered as signs of ageing. However, an emerging study suggests that minor differences in walking patterns could be subtle, early indicators of Parkinson’s disease. According to the study, these signs can can emerge years before Parkinson's diagnosis.

Published in the Journal of Neural Transmission, the study analysed movement data from more than 73,000 participants in the UK Biobank. Researchers found that certain changes in walking behaviour could indicate a future Parkinson’s diagnosis, surfacing up to 6.8 years beforehand.

The findings indicate that Parkinson’s disease may begin developing long before its more familiar symptoms like tremors and stiffness, become noticeable.

Findings From The Study

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Researchers examined data from 73,413 people who wore wearables that track movement for seven days. Their health records were then followed for up to 10 years. Of the participants without Parkinson’s at the time of the movement assessment, 314 were diagnosed with the disease during follow-up.

Using a digital analysis tool called Watch Walk, researchers examined 17 characteristics related to gait. They identified five walking characteristics that were consistently linked with a subsequent Parkinson’s diagnosis:

• Fewer steps each day: Participants who later developed Parkinson’s recorded lower daily step counts than those who did not.
• Slower walking speed: People who were diagnosed later tended to walk more slowly, including at their maximum walking speed.
• Shorter walking periods: They also spent a lesser amount of their time walking in longer, continuous stretches.
• Changes in step regularity: Their steps showed less consistent rhythm, indicating alterations in the regularity of their walking pattern.
• Reduced natural arm swing: They spent more time walking with their arms in a static position instead of swinging naturally.

Effects Of Parkinson’s Disease On Walking

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Parkinson’s disease is a progressive neurological disorder that affects movement. It occurs due to the loss of nerve cells that produce dopamine in a brain region called the substantia nigra. Dopamine helps regulate movement, coordination and other functions.

As dopamine levels decline, the brain's ability to coordinate movement is affected. This can lead to bradykinesia, or slowness of movement, rigidity of muscle, tremors and balance issues.

These changes can also affect gait. A person may take smaller steps, walk more slowly, experience difficulty moving or reduced swinging arms.

The study's findings suggest that some of these motor changes may be detectable in everyday movement well before the condition is formally diagnosed.

Changes in walking speed, balance, step length or arm movement can occur for several reasons, including ageing, joint problems, injuries, medication effects and other neurological conditions.

Parkinson’s disease is, however, diagnosed through a clinical assessment, which considers a person's symptoms, medical history and neurological examination. Other symptoms that may warrant medical evaluation include:

• A tremor especially when the affected hand or limb is at rest.
• Slowness in everyday movements like dressing or getting up from a chair.
• Muscle stiffness or rigidity.
• Problems with balance.
• Smaller handwriting or changes in speech volume.

Early Detection Of Parkinson’s Disease

Although there is currently no established treatment that stops or reverses the underlying progression of Parkinson’s disease, an earlier diagnosis can help people manage symptoms, access rehabilitation and support sooner.

Exercise, physiotherapy and medical care can help maintain mobility, balance and quality of life. Early assessment can also help doctors distinguish Parkinson’s from other conditions that may cause similar movement difficulties.

After the social media trend of ‘ferritin face’ had everyone scrutinising their face for pale skin, dark circles and sluggish features due to low iron levels, attention is now shifting to hair. Described as ‘ferritin hair’, social media users have been attributing symptoms like unusual hair shedding, thinning and brittle strands to the body’s low iron stores.

The trend is not just a fluke. There is a medical basis for recognising iron deficiency in people facing hair loss. However, ‘ferritin hair’ is not a formal medical diagnosis. Hair loss can be due to several reasons, including hormonal changes, stress, thyroid disorders, nutritional deficiencies and genetic hair-loss conditions.

So is there a connection between ferritin and hair health and which signs should prompt someone to seek medical advice?

What Is Ferritin And How Is It Connected To Your Hair?

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Ferritin is a protein that stores iron in the body and releases it when needed. A blood ferritin test helps assess the body's iron reserves. Iron is essential for several functions, including the production of haemoglobin, which carries oxygen in the blood.

When iron stores are exhausted, the body prioritises essential functions over those that are not absolutely necessary for survival. Hair growth may be affected in some people, contributing to increased shedding.

A 2023 clinical review published in Cutis noted that measuring serum ferritin can be useful while evaluating people with diffuse hair loss, especially to identify underlying iron deficiency.

A 2026 study published in Cureus reported that low serum ferritin and telogen effluvium in women may be connected.

A separate systematic review published in 2026 also found lower ferritin levels among people with telogen effluvium.

The European Food Safety Authority has also observed a cause-and-effect relationship between iron intake and the maintenance of normal hair growth.

Possible Signs Of 'Ferritin Hair'

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Hair shedding: One possible sign is diffuse hair shedding, in which more hair than usual falls from across the scalp rather than from one specific area. This can occur due to a condition called telogen effluvium, in which more hair follicles than usual enter the resting phase of the hair-growth cycle.

Hair thinning: Constant shedding can make the hair appear less dense over time. Some people may notice a wider-looking parting or thinner volume.

Dry or brittle hair: Iron deficiency may cause dry, brittle hair. However, hair texture can also be affected by heat styling, chemical treatments and other nutritional factors.

Other symptoms: Hair shedding may occur with other signs of iron deficiency like fatigue, weakness, poor concentration, breathlessness, palpitations or pale skin.

Causes Of Iron Deficiency Or Low Ferritin Levels

Iron deficiency can develop when the body loses more iron than it absorbs and does not receive enough through diet. Heavy menstrual bleeding and pregnancy are common reasons for iron deficiency. Other possible causes include:

• Inadequate dietary iron: People who do not consume enough iron-rich foods are at risk if their diets are restrictive.
• Poor absorption: Conditions such as coeliac disease can interfere with the absorption of iron.
• Blood loss: Gastrointestinal conditions like gastritis and intestinal polyps can sometimes lead to iron loss.
• Increased requirements: Pregnancy can demand increased iron needs.

Delhi’s air pollution has worsened even before the onset of peak winter. This has raised concerns about development and health of children who are constantly exposed to high levels of fine particulate matter (PM2.5).

While the immediate effects of polluted air like coughing, wheezing and breathing difficulties are known, research says that long-term exposure can also impact children’s developing brains, including effects on their memory, attention, IQ and ability to learn.

Delhi Winter Pollution Highest In 3 Years

On November 12, Delhi's air quality got listed under 'very poor' category. Stations like IIT Delhi and Delhi IITM recorded an AQI of 416, while NSUT Jaffarpur and Delhi DPCC recorded 404. Anand Vihar station recorded 319 while DTU Delhi stated 372.

A new analysis by the Centre for Science and Environment (CSE), released recently, found that Delhi’s average PM2.5 concentration during the week preceding Diwali stood at 236 micrograms per cubic metre (µg/m³), the highest in the last three years. This was 97% higher than the 120 µg/m³ recorded in 2025 and 32% above the 179 µg/m³ recorded in 2024.

The analysis also found that pollution levels during the early winter period were higher this year than in 2025. Vehicular emissions and pollution from neighbouring NCR districts were among the major contributors. The findings suggest that firecracker smoke from Diwali aggravated an already high pollution burden.

Delhi’s pollution crisis is not only threatening people’s lungs and cardiovascular health, it is also posing significant risks to children’s brain health. Could breathing polluted air affect how well children concentrate, recall information and learn at school?

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Effects Of PM2.5 On Children’s Cognitive Health

PM2.5 refers to fine particulate matter with a diameter of 2.5 micrometres or smaller. These particles are small enough to travel deep into the respiratory system, fueling inflammation and oxidative stress. Not just lungs, their effects may reach children’s nervous systems.

Dr Sushil Singla, Director, Paediatrics, Sarvodaya Hospital, Sector 8, Faridabad told HealthandMe, “Exposure to PM2.5 (fine particulate matter) can affect children's cognitive development, including memory, attention span and learning abilities. These tiny particles can penetrate deep into the lungs and may trigger inflammation and oxidative stress, which can have wider effects on the developing brain. Children are particularly vulnerable because their brains are still developing and they inhale more air relative to their body weight than adults.”

The developing brain goes through significant changes throughout childhood. Processes involved in learning, memory, attention and executive function continue to evolve during these years. Exposure to environmental pollutants during fragile developmental periods is therefore a huge concern.

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Effects On Learning And Academic Performance

Difficulties in paying attention, memorising and processing complex information can make it harder for children to follow lessons in the classroom.

“Prolonged exposure to high levels of air pollution has been associated with difficulties in concentration, attention, information processing and memory. This may also affect a child's learning abilities and academic performance over time. Although the extent of the impact varies depending on the duration and intensity of exposure, parents should take preventive measures,” says Dr Singla.

What Does Science Say?

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Several studies suggest that air pollution exposure may be associated with poorer cognitive outcomes in children.

A review and meta-analysis published in Environmental Health in 2024 examined six studies involving 4,860 children across North America, Europe and Asia. It found a statistically significant association between higher PM2.5 exposure and lower IQ scores. The researchers reported that every 1 µg/m³ increase in PM2.5 was associated with a 0.27-point decrease in full-scale IQ.

A 2022 review of 86 studies also found evidence between particulate matter exposure and poorer executive function in children, specifically working memory. Executive function refers to a set of mental skills that help children plan, focus attention, remember instructions and manage multiple tasks.

Recent research based on data from the US Adolescent Brain Cognitive Development (ABCD) study also showed that PM2.5 exposure was linked with smaller hippocampal volumes and lower working-memory in young people.

The hippocampus is a brain region involved in learning and memory. The researchers suggested that exposure during both prenatal development and late childhood could affect brain structure and function.

What Can Parents Do?

While individual precautions cannot eliminate the pollution burden, they can help reduce exposure. Dr Singla advises parents to monitor AQI levels, limit outdoor activities during peak pollution hours and ensure adequate indoor ventilation. Other measures include:

• Check air quality before outdoor activities: Avoid outdoor sports, running and strenuous exercise when pollution levels are high.

• Keep windows closed during pollution episodes: Ventilate rooms when outdoor air quality improves. Where possible, use an air purifier with a HEPA filter.

• Use a well-fitting N95 mask: A respirator can reduce exposure to particulate matter when children need to be outdoors.

• Follow school advisories: Parents should stay informed about changes to outdoor classes, sports and school schedules during severe pollution days.