For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

• Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
• Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
• Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
• Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

Breastfeeding is important not only for babies' health and nutrition but also for protecting mothers from serious diseases, the World Health Organization (WHO) said.

It urged governments to strengthen access to services and interventions that support breastfeeding as part of World Breastfeeding Week, observed annually from August 1–7.

The 2026 theme, "Breastfeeding for a Sustainable Start in Life: Strengthen What Works," focuses on tracking progress, evaluating impact, and scaling proven approaches that improve breastfeeding outcomes.

Breastfeeding Could Save Hundreds of Thousands of Lives

"Scaling up breastfeeding could prevent almost 400,000 child deaths and around 140,000 maternal deaths each year," said UNICEF Executive Director Catherine Russell and WHO Director-General Dr. Tedros Adhanom Ghebreyesus in a joint statement.

"Every US$1 invested in breastfeeding promotion generates an estimated US$59 in economic returns through lower health-care costs, improved cognitive development, higher educational attainment, and increased lifetime earnings," they added.

Health Benefits for Babies and Mothers

The experts noted that breastfeeding is one of the simplest and most powerful ways to protect a child's health. It provides infants and young children with essential nutrition, boosts immunity, helps protect against serious illnesses, and supports cognitive development.

For mothers, breastfeeding also offers significant health benefits by reducing the risk of noncommunicable diseases such as breast and ovarian cancers, and type 2 diabetes.

Global Breastfeeding Rates Have Improved

The WHO said breastfeeding rates have improved globally due to sustained investments in policies and programs supporting mothers and families.

Exclusive breastfeeding during the first six months increased from around 37 per cent in 2012 to more than 47 per cent today. Over the past five years, the prevalence of breastfeeding up to two years of age has risen from 38 per cent to 50 per cent.

Progress Remains Uneven

Despite these gains, the WHO said many countries continue to lag behind global targets.

"Coverage of services supporting breastfeeding remains low, policies are inconsistently enforced, and service quality is often inadequate, especially in low-income, fragile, and humanitarian settings," the WHO said.

The agency noted that cost-effective interventions include skilled breastfeeding support within health systems, community-based counselling, maternity protection policies, and protection from the exploitative marketing of commercial milk formulas.

WHO, UNICEF Call for Stronger Support

WHO and UNICEF called on governments, health systems, workplaces, communities, civil society organizations, and families to strengthen the "Warm Chain of Support" for breastfeeding.

During World Breastfeeding Week, the agencies urged countries to:

• Strengthen health systems to provide quality breastfeeding support for mothers and newborns.
• Expand community-based counselling and peer support programs.
• Fully implement and enforce the International Code of Marketing of Breast-milk Substitutes.
• Invest in paid maternity leave and supportive workplace policies.
• Integrate breastfeeding interventions into antenatal, perinatal, and postnatal health-care services.
• Sustain breastfeeding support in humanitarian and fragile settings.

"Breastfeeding is vital. By investing in proven solutions, we can give every child the best possible start in life and ensure every mother gets the care and services she needs," the agencies said.

A new study published in The Lancet Regional Health–Southeast Asia has found that India accounts for 68% of all childhood cancer cases in the SAARC region.

While the country's large child population contributes to the high numbers, experts say underdiagnosis and incomplete cancer registration may mean the actual burden is even greater.

An international team of researchers, including from the US, India, and Canada, estimated that nearly 37,700 children aged up to 14 years were diagnosed with cancer across South Asia in 2022, with 17,700 deaths reported. India alone accounted for an estimated 25,939 cases and 12,028 deaths.

The researchers noted that because cancer registration remains incomplete, particularly in rural areas, the true number of childhood cancer cases in India could exceed 50,000 annually.

India's Large Child Population Drives Numbers

India is home to more than 380 million children, accounting for nearly 69% of the child population in the SAARC region. This naturally contributes to the country's higher share of childhood cancer cases and deaths.

However, experts emphasize that population size is only part of the explanation. Delayed diagnosis, limited access to specialized treatment, and gaps in cancer registration continue to affect both disease estimates and patient outcomes.

Leukemia Most Common Cancer

Dr. Narendra Agrawal, a leading Hematologist and Bone Marrow Transplant Physician and Senior Consultant and Unit Head of Haemato-Oncology at Rajiv Gandhi Cancer Institute & Research Centre, told HealthandMe that childhood cancer remains a major public health concern in India.

"Current estimates suggest that around 70,000–80,000 children and adolescents develop cancer each year, although the exact number remains uncertain due to expanding cancer registration systems". The most common childhood cancers in India include:

• Leukemia
• Lymphomas
• Brain tumors
• Bone tumors

What Causes Childhood Cancer?

Unlike many adult cancers, most childhood cancers do not have a clearly identifiable or preventable cause. Dr. Agrawal explained that, in most children, cancer develops because of genetic changes that occur during early development. These changes are usually not linked to lifestyle factors or inherited from parents.

Recognized Risk Factors

Although the causes of most childhood cancers remain unclear, some well-established risk factors include:

• Ionizing radiation: High-dose exposure before birth or during childhood increases the risk of leukemia and certain other cancers.
• Genetic syndromes: Conditions such as Down syndrome, Li-Fraumeni syndrome, and neurofibromatosis increase susceptibility to specific childhood cancers.
• Certain infections: Epstein–Barr virus (EBV) is associated with some lymphomas, HIV increases lymphoma risk, and chronic hepatitis B infection raises the risk of liver cancer.
• Environmental and parental exposures: Tobacco smoke, certain chemicals, pesticides, and some occupational exposures have been investigated as possible risk factors, although evidence remains inconclusive.

Challenges Beyond Disease Burden

Dr. Agrawal said India's substantial childhood cancer burden is largely driven by its population size. However, improving outcomes requires addressing several systemic challenges.

Key issues include:

• Delayed diagnosis
• Limited access to specialized pediatric oncology services in some regions
• Treatment abandonment
• Incomplete cancer registration

One of the patients I operated on recently had every reason to undergo surgery as early as possible. His reports were clear. His diagnosis was straightforward. From a medical standpoint, there was little ambiguity about the next step. Yet he did not schedule the surgery.

Not because he did not trust me or because he wanted another opinion. He simply was not ready. When we spoke again, it was not his cancer that was worrying him, but whether he would be able to leave a normal life after surgery. He was worried about whether his relationship with his wife and becoming a burden on his children. Somewhere along the way, he had also spent a few nights reading forwarded messages and YouTube comments that convinced him life after prostate surgery would never be the same again.

None of those fears appeared in his MRI. None of them were mentioned in his blood reports. But every one of them had the power to delay the treatment that could save his life.

This is not a rare story in Indian hospitals. It is, in fact, an everyday one. In a country where families, not individuals, usually carry a diagnosis together, these moments happen in almost every cancer ward, every single day. No scan, blood test or surgical robot can detect them.

As clinicians, we learn to recognise these patterns almost instinctively. We know which patient is quietly terrified despite appearing calm. We know when a wife is more anxious than the patient himself. We know when a family has understood the diagnosis and when they are simply too overwhelmed, or too far from a good hospital, to process it. The conversation around artificial intelligence in Indian healthcare is missing something important.

Efficiency Is Not Where AI Will Matter Most

Most discussions here focus on efficiency, and understandably so. India carries a genuine shortage of doctors relative to its population, and the government has been working to close that gap by pushing toward the World Health Organisation's recommended doctor-to-patient ratio. Against that backdrop, it is natural that AI gets framed as a force multiplier: it will reduce documentation, summarise records, automate hospital workflows, help one doctor do the work of three. All of that is valuable, especially for a country of our size and diversity.

But efficiency is not where AI will have its greatest impact on Indian healthcare. Its greatest opportunity lies in understanding and supporting human behaviour, at a scale our clinics were never built to handle.

India has, over the last few years, quietly built the infrastructure to make this possible. Through the Ayushman Bharat Digital Mission, the country has created one of the largest digital health identity systems anywhere in the world, with digital health accounts now numbering in crores, connecting patients, hospitals, laboratories and pharmacies through a common digital framework. Clinical decision-support tools built on this backbone are already being rolled out across tens of thousands of hospitals, cross-referencing symptoms and treatment protocols while leaving the final call with the doctor. That last part matters more than it might seem. The scaffolding exists. What we build on top of it is still an open question, and it is a question doctors cannot afford to sit out.

Also read: Ayush Ministry, IndiaAI Join Hands To Boost AI-Driven Innovation In Traditional Medicine

Imagine the Version That Was Built Around the Patient

Imagine if the patient who went home after meeting a doctor did not have to rely on midnight searches and forwarded videos to make sense of his diagnosis. Imagine if he could ask questions in Kannada, Hindi, or any other language he was most comfortable in, and get answers grounded in his own treatment plan, not someone else's story from an online forum. In a system where a single specialist may be the only uro-oncologist within reach of several districts, that kind of early flag can be the difference between a curable case and one that is not.

None of this replaces medicine. It strengthens it. And this is precisely why Indian doctors need to play a much bigger role in shaping healthcare AI, not as advisors brought in at the end, but as co-architects from the start.

Also read: Bryan Johnson's New 2.6M Women's Health Project Centers on Girlfriend's Menstrual Blood

Why This Has to Be Doctor-Led, and Why It Has to Be Indian

Technology companies are exceptionally good at building software. But they don't spend every day sitting across from a patient whose biggest obstacle is overcoming everything that comes with it: the fear of becoming a financial burden on the family, the silence that comes from a diagnosis nobody wants to say out loud at home, the distance between a district hospital and the nearest oncology centre.

Doctors witness those moments every day. We know where patients hesitate. We know which questions never get asked, often because asking them feels like admitting weakness in front of the family. We know where a well-meaning relative's advice, or a health forward on WhatsApp, can undo weeks of careful counselling in a single evening. Those observations are incredibly valuable, and right now, most of them stay locked inside consultation rooms.

An AI model trained largely on Western clinical and behavioural data will not automatically understand what it means to deliver a cancer diagnosis in a joint family setup, or why a patient in a smaller town might trust a local health worker's word over a hospital pamphlet, or why "cost of treatment" is often the real first question a patient wants answered but is too hesitant to ask directly. These are not edge cases in India. They are the norm. If Indian doctors don't help shape these systems, we will end up importing tools that are clinically sound but culturally tone-deaf, and patients will simply stop using them.

If we want artificial intelligence to genuinely improve healthcare in India, this is where we should begin: not with diseases, but with journeys. Not with technology for its own sake, but with a deeper understanding of how Indian patients and Indian families actually navigate illness. We already have the digital foundation for it. What we need now is for enough doctors, across enough specialities and enough parts of the country, to insist on being in the room when these systems are designed, not just when they are ready to be deployed.