For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

• Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
• Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
• Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
• Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

Bob Harris, the renowned BBC Radio 2 host, has informed his listeners of being hospitalized again for prostate cancer treatment.

Posting on social media platform Instagram, Harris said he is receiving treatment for an issue that has developed over the past few weeks.

“As many of you know, I suffer from prostate cancer, and every now and again I experience setbacks that need attention. Now is one of these moments,” he wrote, along with a picture of himself lying in a hospital bed while smiling for the camera.

Harris noted that he’s taking short break away from his programs. However, he confirmed that this week’s Country Show is scheduled as planned, and his Sounds of the 70’s episode on 12th April will feature an 80th birthday celebration special he recorded before attending the C2C Festival with Zoe Ball.

Noting that he can’t state the day of his return as the host, he said: “I know that I will come back… and come back stronger”.

“I hate missing programs and I am keen to get back into the studio as soon as I can”.

Calling himself “blessed” for the support he received from friends and family and listeners of his show, Harris said that during his absence, Darius Rucker will guest on Country, while Shaun Keaveny will cover Sounds of the 70’s for a few weeks.

"I am so blessed to have the love of my family and the support of my friends who have rallied round me at what has proved to be an unexpectedly testing time,” Harris said.

Prostate Cancer: The UK’s Most Common Male Cancer

Prostate cancer remains the most common cancer among men in the UK, with around 55,000 cases diagnosed every year. Despite this, there is currently no national screening program because of concerns over the accuracy of PSA tests.

In November 2025, former UK Prime Minister David Cameron revealed his prostate cancer diagnosis and also called for a targeted screening.

Also read: Joe Biden Is Diagnosed With Aggressive Prostate Cancer: All That You Need To Know

In an interview with Times, he said, "You always hope for the best. You have a high PSA score - that is probably nothing. You have an MRI scan with a few black marks on it. You think, ‘Ah, that’s probably OK.’ But when the biopsy comes back, and it says you have got prostate cancer. You always dread hearing those words. And then literally as they’re coming out of the doctor’s mouth you’re thinking, ‘Oh, no, he’s going to say it. He’s going to say it. Oh God, he said it.’"

The former PM, said that he had a prostate-specific antigen (PSA) test for the screening that looks for proteins associated with the form of the disease. His result was high, and a biopsy after that revealed his cancer.

In October 2024, six-time Olympic gold medallist Chris Hoy revealed he had been diagnosed with terminal stage 4 cancer. His prostate cancer had spread to his shoulder, pelvis, hips, ribs and spine.

A woman’s health check-up is not about being paranoid. It's about refusing to treat your body as an afterthought.

You may not be able to control every diagnosis you ever get. But you can control how late you meet it. That's what preventive care is all about. Early detection through these screenings helps manage hormonal changes, cancer risks, and metabolic health.

From routine blood tests to specialized screenings, Dr. Supriya Bali, Director, Internal Medicine, Max Super Speciality Hospital, Saket, spoke to HealthandMe on specific tests crucial for women, right from their 20s

In Your 20s: Laying A Strong Foundation

Your 20s are all about establishing healthy habits that will carry you through life. Even if you feel great, this is a crucial time to get in the habit of seeing your doctor regularly.

Recommended screening includes:

• Blood pressure check – Every 1-2 years if normal; more often if elevated
• Pap smear – Start at age 21 (or by age 25 if you’ve never been sexually active); every three years if results are normal
• Chlamydia and gonorrhea screening – Annually for sexually active women under 25
• HPV vaccine – If not already completed by 26
• Skin check – Monitor moles and sun damage, especially if you tan easily
• Mental health screening – Don’t ignore stress, anxiety, or depression

In Your 30s: Reproductive And Preventive Health In Focus

As the body begins to undergo subtle changes in the 30s, regular screenings, hormonal health checks, and lifestyle adjustments are increasingly important.

Recommended screenings in 30s include:

• Pap + HPV co-test – Every 5 years starting at 30 (or Pap every 3 years)
• STI screening – Based on risk factors and symptoms
• Blood pressure and cholesterol check – Especially if you have a family history
• Blood sugar test – Especially if you’re planning a pregnancy or have had gestational diabetes
• Breast exam – Regular self-monitoring and breast ultrasound if you suspect a lump.
• Mental health and sleep – Ongoing check-ins with your doctor
• Fertility discussions – If you're planning or delaying pregnancy

Also read: 'Husband Stitch': A Medical Necessity Or Just A Tool To Objectify Women's Bodies?

In Your 40s: Monitoring Long-Term Risk Factors

This is a time when early signs of chronic conditions may start to show up, especially if there’s a family history of heart disease, diabetes, or cancer.

You should get these screenings at certain times:

• Mammography screening: Begin at 40 years of age (earlier if you have a family history of breast cancer).
• Pap smear & HPV test: Pap and HPV every 5 years or Pap alone every 3 years.
• Cholesterol & Blood Pressure Testing: Every 1-2 years.
• Blood glucose test (diabetes screening): especially if you're overweight or at risk for diabetes.
• Thyroid function testing is optional—especially if you feel tired, cold, or have been losing weight or have changes in your bowel habits.
• Weight discussions regarding healthy nutrition and active lifestyle—assist with maintaining a healthy weight.
• Perimenopause begins in your 40's; if you experience mood swings or changes in sleep, hot flashes, or irregular cycles, please speak with your doctor.

Also read: What Your Mammogram Says About Your Heart?

In Your 50’s: Maintain Strength, Stay Ahead of Aging

Maintaining your strength, the ability to prevent illness/disease from affecting you, and remaining proactive against the challenges that arise due to aging will be your focus at this stage.

Every individual will have their own unique series of recommended screenings; however, everyone will benefit from some type of recommended screening.

Some commonly recommended screenings include:

• Mammogram screening program; every 1-2 years.
• Colorectal cancer screening, beginning at age 45 through age 75.
• Bone density scan-if at high risk.
• Hearing/Vision checks annually or as required (on an as-needed basis).
• Blood pressure, cholesterol, and diabetes screening every year.
• Lung cancer screening among those with a history of smoking.
• Vaccines--including shingles, pneumonia, flu, and COVID-19 booster.
• Cognitive screening - to discover memory concerns, changes in mental sharpness, or cognitive function.

Vapes were marketed as a safer option than cigarettes, but research now shows they carry serious health risks -- from lung damage to meningitis to cancer.

Vaping has been a serious concern in the United States, with New York Attorney General Letitia James in 2025 filing a lawsuit against e-cigarette manufacturers and distributors.

The lawsuit accused the companies of fueling a youth vaping crisis, alleging that these companies that manufacture vapes, especially with flavors, have misled consumers about the safety of their products while deliberately targeting young people through deceptive marketing.

Now, a new study, published in JAMA Network Open, has for the first time assessed trends in young children's nicotine exposures across all types of products.

Shockingly, electronic cigarette-related incidents increased 243 percent over the past eight years in young children, especially among those under five years of age, said researchers from the Rutgers New Jersey Medical School.

In contrast, tobacco exposures from conventional products such as cigarettes decreased by 43 percent.

Unlike cigarettes, these devices are often ready to use, brightly colored, require little effort to activate, and appear more like toys than a harmful product.

"This significant spike in children breathing in these substances tells us the risk has changed: It's no longer just about a toddler swallowing something they found on the floor," said lead author Perry Rosen, who conducted the research at the New Jersey Poison Control Center.

"Many recent cases involve children actively using e-cigarette devices after gaining access to them," Rosen added.

Key Findings

The findings were based on an analysis of more than 92,000 reported nicotine exposures in children ages 5 and younger between 2016 and 2023.

The researchers noted that vaping risks often involved children who inhaled the vapors directly from the devices. They also found that children exposed to e-cigarettes were more likely to require a visit to a health care facility compared with those exposed to cigarettes.

According to researchers, young children naturally mimic the behaviors they see around them. So, parents and caregivers must keep vaping devices away from the reach of young children.

Previous research has shown that even moderate ongoing nicotine exposure can lead to lasting health effects on developing lungs, including increased risk of bronchitis and worsening asthma.

"When children see caregivers or older family members vaping, they may copy that behavior—bringing the device to their mouth and inhaling—without any understanding they are exposing themselves to a harmful substance," said Diane Calello, executive and medical director of the New Jersey Poison Control Center.

Vaping: A Concern

Vaping has become a more common form of tobacco use among American middle and high school students.

As per the US Centers for Disease Control and Prevention (CDC), nearly 1.6 million students used e-cigarettes in 2024, with 87.6 percent of them opting for a flavored product.

It is the flavor that makes it even more addictive, and people want to keep smoking it, resulting in it being emptied and refilled way more quickly.

This means those who smoke flavored cigarettes consume more tobacco than those who smoke unflavored ones.