Migraines In Women: How Hormones Influence Neurological Health

Updated Dec 15, 2024 | 11:00 PM IST

SummaryThe hallmark of migraine is its pulsating, unilateral pain, lasting from 4 to 72 hours, often preceded by aura—transient neurological symptoms such as visual disturbances or tingling sensations.
Migraines In Women: How Hormones Influence Neurological Health

Migraines In Women: How Hormones Influence Neurological Health

For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

  • Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
  • Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
  • Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
  • Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

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Men's Health: Here's Five Important Things To Remember

Updated Jun 18, 2026 | 07:00 AM IST

SummaryHeart disease remains one of the leading health risks for men worldwide. The good news is that many cardiovascular risk factors are largely preventable. A healthy weight, physical activity, and a balanced diet can significantly improve heart health.
Men's Health: Here's Five Important Things To Remember

Credit: iStock

Men often carry the responsibility for their families. They work hard and manage professional pressures to provide the best for their loved ones. Yet, many men tend to neglect their own health, the one thing that makes everything else possible.

Across age groups, men often seek medical attention only when the problem becomes severe or when symptoms become impossible to ignore. The most unfortunate thing regarding health is that many health conditions develop silently for years before showing signs. Taking care of yourselves is not selfish; it is essential. After all, the healthier you are, the better equipped you are to support your family, pursue your goals, and enjoy a fulfilling life for years to come.

Prioritize Preventive Health Checkups

One of the best ways to keep an eye on your health is by scheduling regular health screenings. Many conditions, including High BP, Diabetes, high cholesterol, liver disease, and kidney disorders, may not cause noticeable symptoms in the early stages. Annual health checkups can help identify potential problems way before they become serious.

Depending on age and family history, men should also discuss appropriate cancer screenings. Early detection leads to simpler treatment and better outcomes. Make preventive health checkups a routine. Just as a vehicle performs better with regular servicing, your body also needs regular monitoring.

Muscle Mass Is The Key

Maintaining muscle mass is equally important for men as they age. Muscle plays a vital role in supporting metabolism. Even though it is important for improving insulin sensitivity, protecting bone health, and maintaining strength. You don’t need rigorous exercise daily.

Strength training two to four days a week is sufficient. It may also help support healthy testosterone levels and reduce the risk of chronic conditions like type 2 diabetes and heart disease. The best thing is that strength training doesn’t require spending hours in a gym. Consistency matters far more than perfection.

Sound Mind For A Sound Body

We often say that ‘sound mind in a sound body’. This is even true vice versa. Many men feel pressure to appear strong all the time, which can make things difficult. Stress, anxiety, and depression can affect anyone. Persistent fatigue, irritability, difficulty concentrating, or disrupted sleep may be warning signs.

Keep an eye on such changes. Discussion is not a sign of weakness. Talk to trusted family members, friends, or mental health professionals. It can make a significant difference.

Sleep Is The Real Game-Changer

Quality sleep is one of the most powerful tools for maintaining good health. Generally, adults need between seven and nine hours of sleep each night. It helps the body to repair tissues, regulates hormones, and supports brain function.

Poor sleep is linked to weight gain, increased stress, and weakened immune function. If your morning is often tiring or you are struggling with insomnia, then discuss it with your healthcare professional. Limit screen time before bed and avoid excessive caffeine late in the day. It can help improve sleep quality.

Take Heart Health Seriously

Heart disease remains one of the leading health risks for men worldwide. The good news is that many cardiovascular risk factors are largely preventable. A healthy weight, physical activity, and a balanced diet can significantly improve heart health.

Avoiding tobacco products and limiting alcohol consumption is also helpful. Add vegetables, fruits, lean proteins, whole grains, and healthy fats to your daily diet. Such a diet can support both heart and overall well-being. Daily brisk walk can help improve BP, cholesterol levels, and cardiovascular fitness.

(By Dr Shivam Sharma, Internal Medicine, Shalby International Hospitals, Gurugram)

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Recurring Fever: When Is It A Warning Sign Of A Serious Underlying Disease?

Updated Jun 17, 2026 | 09:04 PM IST

SummaryA recurring fever refers to repeated episodes of elevated body temperature that are separated by days, weeks, or even months during which a person feels completely well.
Recurring Fever: When Is It A Warning Sign Of A Serious Underlying Disease?

Credit: iStock

Fever is one of the body's most common warning signals. In most cases, particularly among children, it is caused by a simple infection and resolves within a few days. However, when fever keeps returning repeatedly, follows a pattern, or occurs alongside other concerning symptoms, it may signal an underlying health condition that requires medical attention.

What Is A Recurring Fever?

Dr. Hemalata Arora, Director of Internal Medicine at Nanavati Max Super Speciality Hospital, Mumbai, told HealthandMe that a recurring fever refers to repeated episodes of elevated body temperature that are separated by days, weeks, or even months during which a person feels completely well.

While recurrent fevers can sometimes result from common viral infections, especially in children exposed to school environments, daycare settings, or seasonal illnesses, persistent or unexplained episodes warrant further investigation.

The expert stated that understanding the pattern of fever is often one of the most important clues in determining the cause.

What Can Cause Recurring Fever?

Dr. Diksha Goyal, Consultant in Internal Medicine at Marengo Asia Hospitals, Gurugram, told HealthandMe that a recurrent fever can occur when body temperature rises to 38°C or higher and reappears after improving or occurs intermittently over time.

Several medical conditions may cause recurring fever, including:

1. Chronic Infections such as tuberculosis (TB), urinary tract infections

2. Autoimmune Diseases

3. Immune System Disorders

4. Cancers, particularly blood-related cancers

5. Certain Viral Infections

Also read: Doctors Call Kratom The ‘Next Addiction Crisis’ As More US States Push Bans

Warning Signs That Should Not Be Ignored

While recurrent fever is not always dangerous, the experts emphasize that certain accompanying symptoms require prompt medical evaluation.

Dr. Arora notes that urgent attention is needed if recurring fever is associated with:

  • Unexplained weight loss
  • Night sweats
  • Persistent fatigue or unusual tiredness
  • Poor appetite
  • Repeated vomiting
  • Breathing difficulties
  • Persistent abdominal pain
  • Confusion or altered mental status

Dr. Goyal added that persistent cough, swollen lymph nodes, and unexplained body pain can also indicate an underlying condition requiring medical treatment.

These symptoms may point toward serious infections, immune system disorders, blood-related diseases, cancers, or inflammatory conditions in which the body's defense system triggers repeated inflammation without a clear infection.

Early Treatment For Better Outcomes

Read More: Taking Duloxetine? US FDA Warns of Cancer-Causing Impurity in Antidepressant

Another important warning sign is a fever that continues to recur despite treatment. According to Dr. Arora, repeated courses of antibiotics without a confirmed diagnosis should raise concern. In some cases, medications themselves can trigger fever, making a detailed medication history an important part of the evaluation.

The goal is not to panic but to seek timely medical assessment. Check for swollen lymph nodes, rashes, signs of infection, or evidence of systemic inflammation.

The experts noted that early medical evaluation can help identify the underlying cause, prevent complications, and ensure appropriate treatment. With timely diagnosis and proper management, many causes of recurrent fever can be effectively treated, allowing individuals to maintain their health and daily activities.

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Trying to Quit Tobacco? Yoga Could Improve Your Chances, Suggests Study

Updated Jun 17, 2026 | 04:57 PM IST

SummaryThe study led by AIIMS Delhi researchers suggests that yoga may serve as a moderately effective intervention for tobacco cessation, with an estimated effectiveness of around 50 per cent.
Trying to Quit Tobacco? Yoga Could Improve Your Chances, Suggests Study

Credit: AI generated image

Tobacco use remains a global epidemic and one of the leading preventable causes of death worldwide. Despite a strong desire among many users to quit, relapse rates remain alarmingly high. A new study by researchers at the All India Institute of Medical Sciences (AIIMS), New Delhi, suggests that yoga could be a valuable tool in helping people quit tobacco.

Yoga Shows Promise for Tobacco Cessation

To evaluate the effectiveness of yoga in tobacco cessation, researchers led by Dr Gautam Sharma, Department of Cardiology and Centre for Integrative Medicine and Research, AIIMS, conducted a meta-analysis of five randomized controlled trials (RCTs) published up to September 2024.

The review included adults aged 18 years and older who used any form of tobacco, excluding vaping products. Participants were randomly assigned to yoga either as a standalone intervention or alongside conventional cessation treatments.

The primary outcome assessed was the 7-day point prevalence abstinence (7PPA), a standard measure of smoking cessation. Secondary outcomes included quality of life, depression, anxiety, and mood states.

The findings suggest that “yoga may serve as a moderately effective intervention for tobacco cessation, with an estimated effectiveness of around 50 per cent”, the team said in the paper.

Also read: Yoga May Boost Fertility And Hormonal Health In Women With PCOS

How Yoga May Help People Quit Tobacco

Researchers found that active yoga styles such as Hatha, Vinyasa, and Iyengar yoga improved abstinence rates by helping reduce stress, depression, and negative emotions often associated with tobacco withdrawal.

Pranayama, or yogic breathing exercises, was found to reduce cravings and negative affect, making it easier for participants to cope with withdrawal symptoms.

The review also highlighted the importance of addressing psychological factors linked to tobacco addiction, including perceived stress, anxiety, depression, and emotional distress—all of which are known contributors to relapse.

While some studies reported stronger psychological benefits than others, overall evidence suggests yoga may support emotional well-being during the quitting process.

Yoga and Tobacco Addiction

Also read: Yoga Shows Promise for Anxiety Relief And Seizure Control In Epilepsy, Claims Study

Researchers believe yoga may help manage tobacco addiction through several biological mechanisms.

Nicotine stimulates nicotinic cholinergic receptors in the brain, triggering the release of neurotransmitters that produce pleasurable and rewarding effects. During withdrawal, stress-related hormones increase, leading to anxiety, cravings, and emotional discomfort.

Yoga appears to counter these effects by shifting the body from a state of sympathetic nervous system dominance ("fight or flight") to parasympathetic dominance ("rest and digest").

Read More: India Launches New Yoga Protocols To Fight Diabetes, High BP, Asthma

This shift may reduce activity in the hypothalamic-pituitary-adrenal (HPA) axis, lower cortisol levels, and decrease stress hormone production, helping individuals better manage cravings and withdrawal symptoms.

The team also noted that controlled breathing techniques can significantly influence emotional regulation, with voluntary breath control accounting for substantial variations in emotional states such as anger, fear, and joy.

India alone has more than 270 million active tobacco users. Given the widespread use of smokeless tobacco in the region—and the limited effectiveness of standard cessation medications for these users—yoga could offer an accessible, culturally familiar, and low-cost complementary approach, the researchers stressed.

While the results are encouraging, researchers also cautioned that larger and more standardized studies are needed.

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