Migraines In Women: How Hormones Influence Neurological Health

Updated Dec 15, 2024 | 11:00 PM IST

SummaryThe hallmark of migraine is its pulsating, unilateral pain, lasting from 4 to 72 hours, often preceded by aura—transient neurological symptoms such as visual disturbances or tingling sensations.
Migraines In Women: How Hormones Influence Neurological Health

Migraines In Women: How Hormones Influence Neurological Health

For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

  • Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
  • Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
  • Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
  • Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

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Delhi Will See Pollution-free Blue Sky In Next 3-4 Years, Says Authority

Updated Dec 31, 2025 | 11:00 PM IST

SummaryDelhi woke up to very poor air quality with dense fog, flight cancellations, and AQI touching severe levels in some areas. Amid the pollution crisis, CAQM has promised more blue-sky days over the next three to four years through long-term measures targeting vehicles, industry, dust, stubble burning, and year-round, data-driven action.
Delhi Will See Pollution-free Blue Sky In Next 3-4 Years, Says Authority

Credits: iStock

Delhi, on Wednesday morning, woke up to 'very poor' air. The visibility was low and, in fact, the India Meteorological Department (IMD) issued an orange alert for dense fog between 8.30am and 10am. Visibility remained low, and as per the 24-hour average Air Quality Index, Delhi stood at 384, as confirmed by the data from the Central Pollution Control Board (CPCB). In certain areas, including Anand Vihar, AQI remained under 'severe' level, at 452.

This has resulted in cancellation of t least 148 flights and over 150 flights were delayed at the Delhi airport.

However, there may be a silver lining, in an interview with TOI, Tarun Kumar Pithode, who took charge as the new full-time member secretary of the Commission for Air Quality Management (CAQM) said that Delhi can expect "more blue-sky days over next 3-4 years".

How Does The Commission for Air Quality Management Plan To Bring Delhi's Pollution Down?

Delhi’s fight against air pollution is set to intensify over the next few years, with the CAQM outlining a multi-pronged plan aimed at delivering “more blue-sky days” for the capital. Rather than relying on emergency measures alone, the strategy focuses on long-term, structural fixes across transport, industry, energy and regional coordination.

Cutting Emissions at the Source

One of CAQM’s core priorities is reducing pollution from vehicles, which remain a major contributor to Delhi’s poor air quality. The plan pushes for faster adoption of electric vehicles, tighter checks on polluting commercial vehicles, and a stronger public transport network. Scrapping old, high-emission vehicles and discouraging diesel use through stricter enforcement are seen as key steps to curb everyday emissions, not just during winter spikes.

Cleaning Up Industry and Power Generation

Industrial pollution is another major target. CAQM has stressed a shift away from coal and other dirty fuels toward cleaner energy sources. Industries operating in and around Delhi are being pushed to adopt cleaner fuels such as natural gas, along with better emission-control technologies. Power plants in the region are also under scrutiny, with stricter norms to ensure they do not become pollution hotspots during peak winter months.

Tackling Dust and Construction Pollution

Construction dust and road dust significantly worsen Delhi’s air quality, especially during dry months. CAQM’s plan includes stricter enforcement of dust-control norms at construction sites, better mechanised road sweeping, and regular water sprinkling on major roads. Authorities are also being asked to improve urban planning to reduce exposed soil and unpaved areas that contribute to dust pollution.

Managing Seasonal Pollution and Stubble Burning

A major part of Delhi’s pollution problem comes from outside the city, particularly crop residue burning in neighboring states. CAQM has emphasized regional coordination, working with states like Punjab, Haryana and Uttar Pradesh to reduce stubble burning. This includes promoting alternative methods for crop residue management, providing financial incentives, and ensuring accountability when violations occur.

Data-Driven and Year-Round Action

Unlike earlier approaches that focused largely on winter emergencies, CAQM’s plan relies on year-round monitoring and data-driven action. Expanded air-quality monitoring, better forecasting, and early interventions are expected to prevent pollution levels from spiralling out of control. The aim is to move from reactive crisis management to consistent prevention.

A Long Road Ahead

CAQM officials acknowledge that Delhi’s pollution problem will not disappear overnight. However, with coordinated action across sectors and states, they believe the capital can see steady improvement over the next three to four years. The promise of more blue-sky days hinges not just on policy, but on strict enforcement and sustained public cooperation.

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As Winter Flu Spreads, Pharmacist Says Be Ready With These 4 Medicines

Updated Dec 31, 2025 | 01:00 AM IST

SummaryStock up on winter essentials before cold and flu season peaks. A pharmacist explains which medicines to keep at home and how early preparation can help avoid unnecessary GP visits in January.
medicines for flu

Credits: Canva

While December arrives with celebrations, food and social gatherings, it is also the time when seasonal illnesses quietly begin to surface. Colds, lingering coughs and flu tend to spread more easily in colder weather, often catching people off guard just as the new year begins. For those hoping to avoid starting January feeling unwell, there are simple steps that can be taken ahead of time.

A pharmacist has urged people to prepare early by stocking up on essential remedies, saying that being organised can help manage symptoms quickly and reduce unnecessary visits to the doctor. According to him, early action makes winter illnesses far easier to handle.

Why Pharmacists Say Preparation Matters Before January

Pharmacists say the key to getting through winter comfortably is preparation before cold and flu season reaches its peak. Keeping a well-stocked medicine cupboard means symptoms can be treated as soon as they appear, without the stress of searching for supplies while already feeling ill.

“Preparation really is half the battle,” said pharmacist Frederick Apenteng from Roseway Labs. “Once you’re unwell, the last thing you want is to be running around looking for paracetamol or trying to buy a thermometer. That’s often when people feel worse than they need to.”

Medicines To Get Ready For Winter Flu

Frederick stresses that starting with the basics is essential. Painkillers such as paracetamol or ibuprofen help manage fever, aches and general discomfort. Throat lozenges or sprays can ease soreness, while keeping two types of cough medicine at home is helpful. One should be an expectorant for chesty coughs, and the other a suppressant for dry, irritating coughs.

The Basics Every Household Should Have

Blocked noses are another common winter complaint, and decongestants can provide quick relief. However, Frederick warns they should not be used for more than five days. For longer-term congestion, saline nasal sprays are a safer option.

Other useful items include rehydration sachets, tissues, hand sanitiser, and honey and lemon for comfort. A digital thermometer allows you to keep track of fever, while vapour rubs or a humidifier can help ease breathing when congestion strikes.

Why Nutrition and Rest Matter for Immunity

Beyond medicines, Frederick highlights the role of nutrition in keeping the immune system strong. “People often feel run down because they’re missing key nutrients,” he explained. “Iron, B vitamins and vitamin C all play important roles in supporting immune defences.”

Eating foods rich in these nutrients, such as leafy greens, citrus fruits and whole grains, can make a noticeable difference. “The biggest immunity boosters are actually sleep, proper nutrition and staying hydrated,” he added.

A Little Planning Now Can Prevent Bigger Problems Later

Preparing in advance can ease both physical discomfort and mental stress. “Having your winter kit ready means you can act quickly at the first sneeze,” Frederick said. “That can stop symptoms from getting worse and helps keep you out of the GP waiting room.”

In short, early rest, basic treatment and preparation can help people move through winter with fewer disruptions.

Be Cautious With Cold and Flu Medicines

While home remedies can be helpful, it is important not to overuse certain products. In some cases, taking too many cold and flu medicines can cause serious problems, including accidental overdose, liver or kidney damage, and rebound congestion.

Always follow dosage instructions carefully and speak to a healthcare professional if you are unsure. Frederick also cautions against prolonged use of nasal decongestant sprays. Using them for more than a few days can trigger a rebound effect, where nasal passages become more blocked than before. This condition is known as rhinitis medicamentosa.

Staying informed, prepared and cautious can make all the difference during the winter months.

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Adenovirus Incubation Period: How Long Does It Take For Symptoms To Appear?

Updated Dec 31, 2025 | 12:00 AM IST

SummaryA mystery virus sweeping the UK has been identified as adenovirus. Learn about its incubation period, symptoms, how it spreads, and who is most at risk this winter.
adenovirus incubation period

Credits: Canva

If you managed to stay healthy this festive season, chances are you still know at least a couple of people who did not. In the days before Christmas and in the weeks that followed, a so-called “mystery virus” has been moving rapidly across the UK.

Many people have reported coughing, sneezing, blocked or runny noses, and in some cases stomach-related problems too. So what exactly is behind this wave of illness? Ian Budd, lead prescribing pharmacist at Chemist4U, has explained which virus is currently spreading widely across the country and what steps you can take to safeguard yourself and your family. He also sheds light on its incubation period.

What Is Adenovirus?

Adenoviruses refer to a large family of viruses that can trigger infections ranging from mild to more serious, affecting different parts of the body. Most often, adenovirus targets the respiratory tract. The symptoms can closely resemble those of a cold or flu. In the majority of cases, adenovirus infections are mild and can be managed with basic care focused on easing symptoms.

Adenovirus Incubation Period

The incubation period for adenovirus usually falls between 2 and 14 days. For many people, signs such as fever, a sore throat, or coughing tend to appear around five or six days after coming into contact with the virus, although this can differ from person to person. Adenovirus spreads easily through droplets released when someone coughs or sneezes, by touching contaminated surfaces, or through fecal-oral transmission. It is highly contagious, particularly in crowded settings, and people may continue to shed the virus even after they start feeling better, according to the National Institute of Health.

One reason the virus appears to be everywhere right now is winter behaviour. Colder weather keeps people indoors for longer periods, increasing close contact with others who may already be unwell.

Ian explained, “With COVID-19 restrictions no longer in place and fewer people being exposed to common viruses over the last few years, overall immunity in the community may be lower. That makes people more vulnerable now.

“Adenovirus itself is not new. It is simply appearing more frequently at the same time as other winter illnesses.”

Adenovirus Symptoms

If you suspect you may have adenovirus, the most common symptoms include:

  • Sore throat
  • Runny or blocked nose
  • Cough
  • Fever
  • Fatigue
  • Headaches or body aches
  • Shortness of breath, which is less common

Other possible signs:

  • Pink eye, also known as conjunctivitis, causing red, watery, gritty-feeling eyes
  • Ear infections, particularly among children
  • Digestive symptoms such as nausea, vomiting, or diarrhoea with certain strains

Who Do Adenoviruses Affect?

Adenoviruses can infect people at any age, but they are especially common in children under the age of five. In babies and young children, the virus often spreads in daycare settings, where close contact is unavoidable. Young children are also more likely to put shared objects in their mouths and are less consistent about handwashing.

Among adults, adenoviruses tend to spread in crowded living conditions. Those who spend time in dormitories or military housing may face a higher risk. The virus can also circulate easily in hospitals and nursing homes.

People with weakened immune systems are more likely to become seriously ill if they contract adenovirus. This group includes individuals who have undergone stem cell or organ transplants, as well as those living with cancer or HIV/AIDS. Those with existing heart or lung conditions also face a higher risk of severe infection.

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