For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

• Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
• Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
• Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
• Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

In 2025, Andhra Pradesh reported 1,566 scrub typhus cases, and nine suspected deaths, according to data from the Integrated Health Information Platform, Integrated Disease Surveillance Programme (IDSP-IHIP) on 8 December. Followed by Karnataka with 1,870 cases, Tamil Nadu 7,308 cases, and Telangana, 309 cases. Scrub typhus cases have significantly increased from previous year. It is one of the deadliest infections affecting multiple organs, or even death. Early it was relevant to poeple working in fields, new studies show it migrating to human settlements.

What Is Scrub Typhus?

Scrub typhus, also known as bush typhus, is a bacterial infection caused by bacteria infection, caused by bacterium Orientia tsutsugamushi. It is spread through bites of infected larval mites, Chiggers.

Most cases of scrub typhus occur in rural areas of Southeast Asia, Indonesia, China, Japan, the Indian subcontinent and northern Australia. Until now, it was believed that chiggers only lurked in the tall grasses of remote paddy fields or dense forests. Due to this, it is commonly known as "farmers' disease", only confined to the fields.

However, new PLOS study data revealed the opposite. The study is led by researchers from Christian Medical College (CMC) Vellore and international collaborators and suggests that the bulk of infections are now even occurring within human settlements.

The study monitored over 32 000 people in Tamil Nadu, which led to the conclusion that agricultural activities, long considered the primary risk factor, were only weakly associated with the disease in high-prevalence areas.

How are Human Settlements A Prime Factor?

Risk for scrub typhus is significantly higher for those living in clustered houses or homes with fewer rooms. If the micro environment around the residence is unmaintained, gardens are patched, or even the damp corners of a courtyard, it could lead to breeding ground for the mites and the rodents that carry Chiggers.

Who Is At Most Risk?

It was once believed that working-age men were the most affected, but the new study tells otherwise. According to the new data, women over 60 are at the highest risk of infection.

As women spend most of their time in and around the home, due to household work, from the kitchen to the laundry, these activities are now the primary cross point of contact with infected mites.

What Is the Risk Factor Of Infection?

As initial symptoms of infection, such as fever, headache, and muscle pain, are the same as viral flu or dengue, many first seek help from untrained practitioners or local pharmacies.

By the time they reach the hospital, the disease has already progressed to severe complications like acute respiratory distress syndrome (ARDS), Kidney failure, or Meningoencephalitis, which is inflammation of your meninges and brain at the same time, a life-threatening condition.

Not only this, the researchers revealed that nearly 10 percent of affected households exceed 25 percent of their income in the treatment.

For severe cases, the cost of treatment can be up to approximately INR 110,000, a staggering sum for rural and peri-urban families earning a fraction of that monthly.

Prevention

• Do not let the grass grow tall around your house
• Tightly maintain kitchen gardens and remove piles of wood or debris where rodents (the primary hosts for mites) might nest.
• As chiggers are usually found close to the ground, do not sit directly on the grass or soil. Use chairs or mats. For children, make them wear socks and full- length trousers while playing in the yard.
• If you notice a small, dark, cigarette-burn-like mark, it is usually left behind by mites. It is most likely "Eschar". It is an important critical clue. As the bite is painless, it often goes unnoticed.
• Do a thorough skin check for an eschar, especially in warm, moist areas like the armpits, groin, or behind the knees.

Early intervention is necessary, as if a fever lasts more than two days, don't just treat it as "seasonal fever".

Consult a qualified doctor and specifically ask about scrub typhus. Infection can be treated with doxycycline common antibiotic, in the early stages. The case fatality rate in this study was 1.5 percent, hospital based studies in South India have previously recorded mortality rates as high 30 percent when treatment is delayed

Shingles, caused by the reactivation of the varicella-zoster virus (the same virus that causes chickenpox), can strike more than once, especially in older adults and people with weakened immune systems. Vaccination against the virus is the most effective way to prevent shingles and related complications, said health experts as part of the Shingles Awareness Week.

The World Health Organization estimates that over 90 percent of individuals worldwide are infected with the varicella-zoster virus, indicating a high susceptibility to shingles.

Health experts explained that the varicella-zoster virus remains dormant in the nerves of the body after an attack of chickenpox.

Dr. Monica Mahajan, Senior Director – Internal Medicine, Max Multi Speciality Centre, Panchsheel Park, told HealthandMe that the virus can remain in an inactive state for two to five decades, or even longer.

When the immunity decreases, the virus can re-activate to cause shingles. The most common symptoms include a rash with sharp, shooting, or stabbing nerve pain.

While it is rare, shingles can recur as one episode of the disease doesn’t grant lifelong immunity.

“It is possible to get shingles infection more than once. An episode of shingles may not give lifelong immunity to the disease. Although it is a rare occurrence, people who have had shingles once can get it again. But those who get vaccinated after the first attack of shingles can prevent the second attack,” Dr. Mahajan said.

How Do Shingles Disrupt Life?

The common manifestation of shingles is a painful blister-like rash, which usually occurs only on one side of the body or face.

It is followed by post-herpetic neuralgia -- a nerve pain that arises in the areas where the rash was located, which often lasts for months or years after the rash has cleared up.

“It is severe and excruciating and is sometimes described as a pain that is worse than chronic cancer pain,” Dr. Chandani Jain Gupta, Dermatologist & Aesthetic Physician, Elantis Healthcare, New Delhi, told HealthandMe.

Dr. Gupta noted that shingles can also affect the eye, impacting the patient's ability to see.

Other less frequent complications of shingles are secondary bacterial infections of the rash, pneumonia, blindness, hearing loss, and neurological complications involving the brain. Fatigue, fever, and sensitivity to touch are other potential complications due to shingles.

Who Is At Risk Of Shingles?

As longevity increases, the phenomenon of ‘immunosenescence’ becomes more common. This means that as we age, our immunity declines, and this process generally starts at the age of 50 years.

"As life expectancy is increasing, more and more people live well beyond the age of 50 years. These people have lowered immunity and are at a higher risk of developing shingles," Dr. Mahajan said.

People who suffer from conditions such as diabetes, HIV, cancer, and patients with kidney or liver transplants are also at a higher risk of shingles because of lower immunity.

Patients who are on certain drugs called the ‘immunomodulators’ (used for conditions like arthritis, lupus, and some skin diseases) that reduce immunity are also more vulnerable to shingles.

How Do Vaccinations prevent Shingles? When to Get It

While some anti-viral medicines can reduce the intensity of the rash and the pain, these are effective only when given within three days of the first symptom. Despite medications, the outcome is not satisfactory in most patients.

But shingles can be prevented with vaccination.

• Adults 50 and older: The CDC recommends that all healthy adults aged 50 years and older receive two doses of the shingles vaccine. The second dose is typically given 2 to 6 months after the first.

• Adults 19 and older with weakened immune systems: If you are 19 or older and have a compromised immune system due to disease (like cancer or HIV) or treatments (like chemotherapy or immunosuppressive drugs). The second dose can be given 1 to 2 months after the first.

A now-viral video has revealed how a new mother who believed she had grown excessive fat tissue instead discovered that her body had developed a third nipple under her armpit.

Jasmine, an American woman had given birth five days earlier when a lactation consultant visited her to giver her advice on breastfeeding. The new mother, who was still exhausted and recovering from childbirth, recalled mentioning that her armpits always carried what she believed was excess fat that darkened during pregnancy.

"I breastfed my first baby for one-and-a-half-years, so I'm thinking that there's nothing this nurse can say that's going to surprise me," Jasmine said.

However, after a careful examination, the expert told her that the swelling in her underarm was extra breast tissue and that she also had "a nipple” there.

"When you're pregnant, your nipples and areolas will get really dark, and I have noticed the same change with my armpits, so I was like 'Great! extra breast tissue, I already knew that.' And then the lactation consultant is like 'Let me see,' and I show her, and she goes, 'Oh! yeah... And that's a nipple'.

"You know how cows and puppies and kittens, they have that line of nipples? Yeah, humans have that, too. Tell me why she's telling me about someone that had an extra nipple on her thigh. Telling me I have a third nipple in my armpit before I even had my first postpartum poop is diabolical work,” she said, joking about how little sleep she’d had.

What Do Experts Say?

• Polythelia: The third nipple is present by itself with no areola (the area of darker skin around your nipple) or underlying breast tissue. This is the most common type of supernumerary nipple.
• Polythelia areolaris: The have an areola present, but no nipple or breast tissue.
• Polythelia pilosa: The have a patch of hair only.
• Polymastia: The third nipple has an areola and has some underlying breast tissue.
• Supernumerary nipple: There is a third nipple that has breast tissue underneath it, but it doesn’t have an areola.
• Supernumerary nipple: There is some breast tissue and an areola, but no nipple is present.
• Aberrant glandular tissue: You have breast tissue, but no nipple or areola is present.
• Pseudomamma: Your third nipple has an areola around it, but instead of breast tissue, you have fatty tissue beneath

According to Dr Rooma Sinha, an obstetrician and gynaecologist at Apollo Hospitals in Hyderabad, Jasmine's third nipple is known as the axillary tail of the breast, a normal extension of breast glandular tissue that tapers into the underarm.

“Some women have axillary tail of the breast. This is probably that. It may produce milk if it has active mammary glands," she told Moneycontrol .

She also confirmed that humans can have supernumerary nipples along what is known as the “embryonic milk line,” extending from the armpit toward the chest. However, this line does not extend down to the thigh, as Jasmine recalled in her video.

According to experts, the axillary tail can feel like a lump or thickened area, particularly during hormonal changes such as pregnancy, breastfeeding or menstruation and may become tender or enlarged.

What Happened Next?

“Regular breast production is sufficient for me,” she said, noting that the extra tissue was painful and that she might consider surgically removing the tissue after she decides not to have more children.