For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

• Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
• Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
• Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
• Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

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Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

Amid reports of the hantavirus outbreak onboard the cruise ship MV Hondius, and two Indian crew members, India’s Ministry of Health and Family Welfare has stepped up surveillance measures.

While the Indian Embassy in Spain has confirmed that the two Indian nationals are currently asymptomatic and are being evacuated to the Netherlands for quarantine, health authorities in the country are closely monitoring the situation in coordination with national and international health agencies.

Notably, the Indian Council of Medical Research (ICMR) has mobilized its formidable "Viral Shield", a sophisticated network of 165 specialized laboratories, called the Virus Research & Diagnostic Laboratory (VRDL), to ensure that the rat-borne virus does not breach the country's borders.

What Are The VRDLs?

The 165 laboratories include

• 11 Regional level,
• 27 State level
• 127 medical college level,
• It covers 31 States and Union Territories of India and functions under the umbrella of the Department of Health Research (DHR)/ ICMR.

Post-pandemic, VRDLs are actively engaged in integrated surveillance for Influenza-like Illness (ILI) and Severe Acute Respiratory Infection (SARI), monitoring for pathogens like Influenza A/B, Mycoplasma pneumonia, and SARS-CoV-2 variants.

In 2025, Union Minister of State for Health and Family Welfare, Anupriya Patel, said, VRDL has stood as “sentinels in protecting the country”.

She added that 16 VRDLs are now equipped with Bio-Safety Level-3 (BSL-3) facilities for studying high-risk pathogens, playing a central role in detecting outbreaks of Nipah, Zika, and Kyasanur Forest Disease.

Also read: Hantavirus: Is Climate Change Behind The Outbreak?

What's The Status Of MV Hondius Passengers?

Amid stiff opposition from the locals, the Dutch-flagged vessel MV Hondius, carrying 94 people, including Filipinos, Britons, Americans, Indians, and Spaniards, arrived in Spain's Canary Islands on May 10. All have been evacuated and repatriated.

Two of the 17 American passengers evacuated from the hantavirus-hit MV Hondius have tested positive, the US Department of Health and Human Services (HHS) announced today.

A French woman onboard the same cruise has also tested positive for hantavirus, and her health worsened in the hospital overnight, French Health Minister Stephanie Rist said.

The woman was among five French passengers repatriated from the MV Hondius.

"It’s not surprising that others on the ship will test positive for hantavirus in the coming days. What’s crucial is that they don’t pass this on to others- those most at risk: who they live with/family/friends as they head home. Quarantine for next 45 days super important," Prof. Devi Sridhar, Professor & Chair of Global Public Health, Edinburgh University, said in a post on the social media platform X.

WHO Guidelines On Hantavirus

Read More: Why The Norovirus Outbreak On A Caribbean Cruise Ship Is Not A Cause for Panic

The WHO maintains that the eight passengers on board have been infected with hantavirus. While three have died, six have been hantavirus infection has been confirmed in six cases.

Dr. Maria Van Kerkhove, the WHO’s head of epidemic and pandemic preparedness, said that after being brought to shore, passengers will be kept cordoned off from the public and taken to repatriation flights.

In their home countries, many will be taken onward to isolation facilities. Van Kerkhove said that the WHO is recommending “active monitoring and follow-up” for all passengers and crew for 42 days from their “last point of exposure” to a confirmed case.

"Our recommendation is daily health checks, at home or in a specialized facility. It's up to countries to develop their policies, but our recommendations are very clear," Van Kerkhove said, highlighting that the incubation period for the virus was up to six weeks.

In my journey as a neonatologist, one truth has remained constant—no healthcare system can succeed without strong nursing care. We often celebrate breakthroughs in technology and clinical expertise, but at the bedside, where outcomes are truly shaped, it is the nurse who makes the difference.

Nowhere is this more evident than in the Neonatal Intensive Care Unit (NICU), a space I have spent decades working in. Caring for extremely premature babies—sometimes born as early as 24–26 weeks—requires far more than advanced machines or protocols. These fragile lives demand minute-to-minute monitoring, swift clinical judgment, and unwavering attention.

It is the nurse who notices the subtle drop in oxygen levels, the slight change in skin tone, or the early signs of infection. Many times, it is their timely intervention that prevents a complication from becoming a crisis. I have witnessed countless such moments—quiet, uncelebrated, yet life-saving.

What we see in practice is strongly supported by global data. Research has consistently shown that for every additional patient assigned to a nurse, the risk of patient mortality increases by nearly 7%. Hospitals with optimal nurse-to-patient ratios report lower infection rates, shorter hospital stays, and significantly better survival outcomes. These are not marginal gains—they are decisive factors in patient care.

And yet, as healthcare advances, a critical gap is becoming increasingly visible.

Over the past five to six decades, medicine has transformed dramatically. We have moved from general practice to highly specialized and super-specialized care—interventional cardiology, robotic surgeries, advanced oncology, and neonatal care that can support extremely preterm infants. These advancements have contributed to a remarkable rise in life expectancy in India—from around 41 years in the 1960s to over 69 years today.

But while medicine has rapidly specialized, nursing training has not evolved at the same pace. This imbalance is one of the most pressing challenges in healthcare today.

The Global Shortage For Nurses

India, like many parts of the world, faces a significant workforce gap. The World Health Organization estimates a global shortage of nearly 6 million nurses. While we continue to train and recruit more nurses, the real challenge lies in specialized skill development. In many hospitals, nurses are assigned to departments based on immediate needs rather than structured career pathways. They learn on the job, often in high-pressure environments, building expertise through experience.

While this speaks volumes about their dedication and resilience, it also highlights a systemic limitation. Specialized medicine cannot function optimally without specialized nursing.

In a NICU, for instance, managing non-invasive ventilation, performing neonatal resuscitation, ensuring strict infection control, and counselling anxious parents are not basic skills—they are specialized competencies. These require structured training, repeated practice, and continuous upskilling.

Bridging The Gap: Training Initiatives In Practice

Recognizing this gap, we recently conducted 10 focused workshops across Karnataka as part of the State Neonatal Nurses Conference. These workshops were designed to strengthen critical skills such as the Neonatal Resuscitation Program (NRP), Non-Invasive Ventilation (NIV), and effective communication within the NICU. What stood out was the response.

Participation exceeded capacity by nearly four times. Nurses travelled long distances, eager to learn, engage, and enhance their skills. This was not just enthusiasm—it was intent. It was a clear indication that nurses are ready to grow, to specialize, and to deliver better outcomes. What they need is access—structured, scalable, and sustained opportunities to learn.

Globally, the impact of investing in nursing education is well documented. Hospitals with a higher proportion of well-trained nurses have reported up to 20% lower mortality rates in certain patient groups. Healthcare systems that prioritize continuous professional development for nurses consistently demonstrate better patient safety outcomes and higher satisfaction levels.

The Need for Systemic Change in Nursing Education

India has begun to take steps in this direction. Initiatives such as the Neonatal Nurse Fellowship introduced by the National Neonatology Forum are important milestones. However, these programs, while valuable, are not accessible to all. Financial constraints, time commitments, and geographical limitations often restrict participation.

This calls for a shift in approach.

Training must move beyond select programs and become an integral part of the healthcare system. We need modular learning formats, simulation-based training, in-hospital skill development programs, and digital platforms that allow continuous learning. Every nurse—irrespective of location or institution—should have access to opportunities that help them grow.

Because ultimately, no matter how advanced our systems become, outcomes depend on the people delivering care.

I often remind my teams of a simple reality—without strong nursing care, the success of any medical speciality is less than 50%.

Beyond systems, statistics, and strategy lies the human side of nursing—a dimension that cannot be measured but is deeply felt.

In the NICU, nurses are not just caregivers to fragile newborns; they are also a source of strength for parents navigating uncertainty and fear. I have seen nurses hold the hands of anxious mothers, explain complex medical situations with patience, and provide reassurance during some of the most difficult moments a family can experience. They are the bridge between clinical excellence and emotional care.

And yet, despite their central role, nurses often remain under-recognized and under-supported. If we are serious about strengthening healthcare, this must change.

Empowering nurses is not just about improving skills—it is about acknowledging their value, creating structured career pathways, and ensuring they are included in decision-making processes. It is about building a culture of respect, where nursing is seen not as support, but as a critical pillar of care delivery.

The future of healthcare will not be defined by technology alone. It will be defined by the strength, capability, and empowerment of its workforce.

And at the heart of that workforce are our nurses. If we want safer hospitals, better clinical outcomes, and resilient healthcare systems, the path forward is clear—we must invest in our nurses, not just in numbers, but in their growth, training, and empowerment. Because in every critical moment I have witnessed, one truth stands out—quietly, consistently, and powerfully: Empowered nurses don’t just support care. Empowered nurses save lives.

Dr. R. Kishore Kumar is President – National Neonatology Forum, Karnataka Chapter

Post-viral syndromes are a classic example of the body not feeling better even after the viraemia is over. When a viral infection ends, most people expect life to quickly return to normal.

For many, it does, but for some, recovery stretches on for weeks or even months. This condition, often called a post-viral syndrome, is now being seen more clearly across the country, especially after the COVID-19 pandemic. Thus, the main question that arises is why doesn’t recovery end when the infection is gone? The answer is that the body does not always ‘reset’ immediately.

Why Symptoms Continue After the Infection Clears?

During an infection, the body’s defense system becomes highly active to fight the virus. In some people, this response does not completely settle down even after the virus has been cleared. This can lead to ongoing tiredness, body aches, or a general feeling of being unwell. This could be due to the immune system remaining partially activated.

In certain cases, the body’s defense system may even start reacting in an unbalanced way, affecting normal tissues. This is why some people develop symptoms like joint pains, palpitations, or dizziness after a viral illness, even though tests may not show an active infection.

Another important reason is energy depletion. Viral infections can temporarily affect how the body produces and uses energy. As a result, even small physical or mental efforts can feel exhausting. Many patients describe a pattern where they feel better, try to return to normal activity, and then feel worse again. This cycle can delay full recovery. The nervous system can also be affected. Some people experience what is commonly called ‘brain fog’, poor sleep, or a sense of imbalance in heart rate and blood pressure. These symptoms are real and are part of the body’s recovery process.

POTS Syndrome

Also, there is something called POT (Positional Orthostatic Tachycardia) syndrome. Patients, when they get up and stand, develop mild giddiness and palpitations.

It is also important to understand that the body may take time to rebuild strength. Muscle loss, physical inactivity, and lack of appetite are common effects following an illness.

Why Recovery Should Not Be Rushed

Consequently, when an individual has recovered from the virus, it is more than just getting rid of the virus. It involves restoring and getting stronger over time. Most importantly, recovery should never be rushed. Pushing too hard or returning to high levels of activity too soon after becoming ill can lead to worsening of symptoms and therefore prolong the recovery time.

A more effective way to recover is by taking a gradual, steady approach. Recovery involves resting adequately, maintaining a nutritious diet, engaging in light exercise and receiving adequate amounts of sleep and at the same time being aware of how your body feels. Long-term symptoms are not in your head. They are part of the process of healing that occurs after some forms of infection.

Most people will recover, but patience and using proper methods are key to recovering completely. It is also important to understand that recovery involves rebuilding the strength that the body needs time to restore this balance.

It is important not to get carried away assuming post-viral syndrome, but consult a physician and not miss out on an underlying medical disorder, and investigate appropriately.