Migraines In Women: How Hormones Influence Neurological Health

Updated Dec 15, 2024 | 11:00 PM IST

SummaryThe hallmark of migraine is its pulsating, unilateral pain, lasting from 4 to 72 hours, often preceded by aura—transient neurological symptoms such as visual disturbances or tingling sensations.
Migraines In Women: How Hormones Influence Neurological Health

Migraines In Women: How Hormones Influence Neurological Health

For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

  • Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
  • Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
  • Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
  • Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

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DAA Hip Replacement: A Modern Technique Helping Patients Recover Faster

Updated Jun 5, 2026 | 12:00 PM IST

SummaryHip pain and mobility issues are becoming increasingly common across all age groups today. Many people struggle with persistent pain while walking, sitting, climbing stairs, or even performing basic daily activities. In many cases, the discomfort gradually affects overall quality of life, limiting independence and confidence.
DAA Hip Replacement: A Modern Technique Helping Patients Recover Faster

Credit: iStock

With advancements in medical technology, hip replacement surgery has evolved significantly over the years. One of the most promising innovations in this field is the Direct Anterior Approach (DAA) Total Hip Replacement, a modern technique that offers patients a safer procedure, reduced pain, and faster recovery.

Unlike traditional hip replacement surgeries, the DAA technique allows surgeons to access the hip joint from the front through a small incision. The biggest advantage of this approach is that muscles are not cut during the surgery. Instead, they are gently separated, which helps minimize tissue damage and reduces post-operative pain considerably.

This muscle-sparing approach has transformed patient recovery experiences. Most patients are able to stand and walk on the same day of surgery, and hospital stays are generally shorter. Recovery is smoother, allowing individuals to return to their normal routine within three to four weeks in most cases.

The DAA technique is especially beneficial for patients suffering from chronic hip pain, restricted movement, or severe joint damage. Common conditions that may require hip replacement include osteoarthritis, avascular necrosis (AVN), rheumatoid arthritis, old hip fractures, and long-standing degenerative joint conditions. When medications, physiotherapy, and injections fail to provide lasting relief, hip replacement surgery can significantly improve mobility and quality of life.

Compared to conventional hip replacement procedures, DAA offers several advantages. The surgery involves a smaller incision, less blood loss, minimal muscle damage, and lower post-surgical discomfort. Patients are able to regain movement faster and often experience greater confidence during rehabilitation.

One of the most common concerns among patients is the fear of severe pain after surgery. However, with modern pain management techniques and advanced surgical methods, discomfort after DAA hip replacement is usually minimal and manageable. Patients today recover much more comfortably than they did in the past.

Another important factor is the durability of modern implants. Advances in implant technology have significantly improved their lifespan, with many implants lasting more than 25 years. Maintaining a healthy body weight, staying physically active, and following medical advice can further improve the longevity and effectiveness of the implant.

After successful recovery, patients are generally able to resume a normal and active lifestyle. They can return to work, perform household activities independently, and participate in light exercises such as yoga, swimming, and stationary cycling. The primary goal of hip replacement surgery is not just pain relief, but restoring confidence, mobility, and independence.

Preparation before surgery also plays an important role in achieving better outcomes. Patients are advised to maintain controlled blood sugar levels, blood pressure, and overall heart health. Informing doctors about ongoing medications, performing basic physiotherapy exercises before surgery, and preparing a comfortable recovery environment at home can contribute to a smoother rehabilitation process.

Hip pain should never be ignored, especially when it begins affecting daily life and mobility. Timely treatment and the right surgical approach can make a remarkable difference. The Direct Anterior Approach has made hip replacement surgery simpler, safer, and more patient-friendly, helping individuals return to an active and pain-free life much faster than before.

Dr. Ishwar Bohra is Senior Director and Senior Joint Replacement Surgeon at BLK-Max Super Speciality Hospital, New Delhi.

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World Environment Day 2026: How Climate Change Is Increasing the Global Disease Burden | Explained

Updated Jun 5, 2026 | 11:08 AM IST

Summary​The theme for World Environment Day 2026 is "Inspired by Nature. For Climate. For Our Future". It focuses on climate change and the signals nature is sending such as rising seas, raging wildfires, heatwaves and melting glaciers.
World Environment Day 2026: How Climate Change Is Increasing the Global Disease Burden | Explained

Credit: AI generated image

Climate change is increasingly emerging as a major public health threat, contributing to a growing burden of disease worldwide and creating favorable conditions for the spread of infectious illnesses, according to health experts on World Environment Day 2026.

World Environment Day is observed every year on June 5 to raise awareness about the need for immediate action as heatwaves intensify, air pollution worsens, ecosystems degrade, and climate anxiety grows worldwide, even as the world crosses the UN-mandated 1.5°C limit.

The theme for World Environment Day 2026 is "Inspired by Nature. For Climate. For Our Future". It focuses on climate change and the signals nature is sending such as rising seas, raging wildfires, heatwaves and melting glaciers.

To understand the intersection between climate change and health impacts, HealthandMe spoke to two experts.

Heatwaves, Pollution And Food Insecurity

According to Dr. Sabine Kapasi, UN advisor, the consequences are no longer limited to environmental damage. Rising temperatures, worsening air pollution and shifting weather patterns are already affecting human health across the globe.

“Longer and more intense heatwaves are resulting in more cases of heat-related illness. Air pollution continues to exacerbate respiratory diseases, while changing weather patterns are impacting food security and nutrition in many parts of the world,” she said.

Importantly, in India, children, pregnant women and communities living in flood- and drought-prone regions face some of the greatest risks. Women are often disproportionately affected due to challenges related to water supply and sanitation. While India has reduced malaria cases by nearly 80 per cent since 2015, climate change is creating new health challenges that health systems will need to address in the coming years.

Infectious Disease Outbreaks

Also read: Dengue Is Spreading Beyond Monsoons And Into New Regions Across India, Says Expert

The expert warned that changing climatic conditions are also increasing the risk of infectious disease outbreaks. Dr. Kapasi told HealthandMe that rising temperatures and altered rainfall patterns are allowing mosquitoes to breed more easily and remain active for longer periods.

Floods further compound the problem by contaminating drinking water, damaging sanitation systems and disrupting healthcare services. Displacement caused by disasters can force families into crowded living conditions, increasing the risk of infections such as cholera, leptospirosis and tuberculosis.

“Recent climate-related disasters in South Asia and Africa have shown how quickly an environmental crisis can turn into a public health challenge,” she noted.

The spread of mosquito-borne diseases such as dengue, malaria and chikungunya is also becoming a growing concern. Health authorities around the world are reporting these diseases in areas where they were previously uncommon.

Globally, countries including Italy, France and Spain have also witnessed an increase in locally transmitted dengue and chikungunya cases over the past decade. In the United States, locally acquired malaria cases were recently reported in Florida and Texas, marking the first such transmission in nearly 20 years.

India is also experiencing rising dengue activity. Dengue outbreaks have become a regular occurrence during the monsoon and post-monsoon seasons in many states. Estimates suggest dengue cases could reach around 278,000 in 2025, up from roughly 230,000 the previous year. Experts say warmer temperatures and changing rainfall patterns are helping disease-carrying mosquitoes survive and spread more effectively.

Climate Change And Shifting Disease Patterns

Also read: Forget Supplements: Barbara O'Neill Says Sleep Is The Best Medicine

Dr. Devarsetty Praveen, Program Director at NIHR GHRC for Non-communicable Diseases and Environmental Change, hosted by The George Institute India, in partnership with Imperial College London, said climate change is affecting both communicable and non-communicable diseases.

“Climate change is increasing health risks through rising temperatures, extreme weather events, worsening air quality and changing disease patterns. In India, it is affecting both communicable and non-communicable diseases, with vulnerable populations bearing the greatest burden,” he told HealthandMe.

He noted that research has found that people living with chronic conditions such as hypertension and diabetes are particularly vulnerable to extreme heat, underscoring the growing link between climate change and non-communicable diseases.

Dr. Praveen added that climate change influences disease transmission by altering temperature, humidity and rainfall patterns while also affecting water quality, food systems and interactions between humans, animals and disease vectors.

“These changes can make outbreaks more frequent, more widespread and harder to predict,” he said.

How To Reduce Climate-related Health Risks

To reduce climate-related health risks, the experts recommend staying informed about weather conditions, remaining hydrated, limiting outdoor exposure during extreme heat and taking precautions against mosquito bites.

People with chronic conditions such as hypertension, diabetes, heart disease and kidney disease are advised to maintain adequate medication supplies and consult healthcare providers during periods of extreme heat.

According to the experts, awareness and early action remain critical to protecting public health as climate change continues to reshape disease patterns around the world.

To reduce the risk of mosquito-borne diseases, people should make sure that water does not get collected in buckets, coolers, flower pots or other containers around the home. Additional precautions include the use of mosquito repellents, sleeping under nets when necessary and wearing clothing that covers the arms and legs.

Dr Sabine said food and water safety is particularly important after heavy rain or flooding. Proper food storage, clean drinking water and good hygiene practices can go a long way in preventing many infections. Those with pre-existing medical conditions should also have essential medicines within easy reach during extreme weather.

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New Study Warns Smog Is Rising Across the US: The Hidden Health Risks

Updated Jun 5, 2026 | 08:59 AM IST

SummaryA recent study finds that smog levels have increased in the United States and may cause serious health hazards in the near future. The main cause of this air pollution is wildfire.
New Study Warns Smog Is Rising Across the US: The Hidden Health Risks

Credit: AI Generated Image

The United States has been working on reducing smog for more than a decade and has become quite successful in this endeavor, but since 2015, the situation has changed for the worse as a new study reveals that the smog level is once again on the rise, and the main reason behind this is another long-term problem of the nation, wildfire.

The federal regulations tightened on power plants, cars, and diesel engines, which in turn caused a drop in the national smog level by 11% from 2003 to 2015. Since then, cases of wildfire have increased, resulting in the smog level going up by 4%. The study finds that if the current trend continues, it will cause smog to go back up to 2003 levels in 20 years.

The study in the journal Science has also calculated a surge in deaths from ozone attacking lungs by comparing death rates in clean and dirty air. They estimated a surge of 318 American deaths per year since 2013 due to smog.

The co-author of the study, Meng Zhou, a University of Iowa wildfire researcher, said, “For the last 20 years, by regulations, we keep decreasing the emissions." He added, “However, because of wildfires, which are actually from natural hazards, all those kinds of effort were wiped out.”

The study also flagged concerns about the current smog situation and its possible impact on the population. University of Washington public health and climate scientist Kristie Ebi said, “Higher daily ozone concentrations can increase asthma attacks, hospital admissions, and mortality.” She added, “still a very important pollutant, which is why it's regulated.”

Also Read: The Mystery Behind Trump’s Hair-Loss Drug And The Bigger Health Questions It Raises

The research finds that the heavy wildfire smoke seasons of 2022, 2023, and 2024, mainly in Canada, created a massive amount of smog, and this then came down south. As a result, about 43 million people got exposed to smog levels that exceeded the current EPA safety standards. The wildfires in Canada have been particularly severe since 2022.

The problem is also with the massive wildfires in the mainland US, as the National Interagency Fire Center's data also shows that the average amount of land in the US that wildfires burn every year has increased by 9% higher than it was from 2003 to 2014.

Also Read: CDC Warns That Tick Bites Are Surging Across The US: What You Need to Know

What Are The Possible Health Impacts?

There are many short-term and long-term impacts on public health from the constant exposure to air pollution. As per IQAir, in the short term, people experience irritation in the eyes, throat, and nose, along with irregular heartbeats, asthma attacks, coughing, chest tightness, and difficulty breathing.

Prolonged exposure also intensifies these risks and leads to long-term effects such as chronic respiratory illnesses like bronchitis, asthma, and emphysema. Pollutants can also damage lung tissue, increasing the likelihood of lung cancer. Air pollution also leads to an increased risk of heart attacks and strokes, and could also be linked to premature death.

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