Migraines In Women: How Hormones Influence Neurological Health

Updated Dec 15, 2024 | 11:00 PM IST

SummaryThe hallmark of migraine is its pulsating, unilateral pain, lasting from 4 to 72 hours, often preceded by aura—transient neurological symptoms such as visual disturbances or tingling sensations.
Migraines In Women: How Hormones Influence Neurological Health

Migraines In Women: How Hormones Influence Neurological Health

For those who have not experienced a migraine, perhaps it would seem just another headache. But for someone like me who has suffered through migraines that will last over a week even with medication, I can definitely tell you that it's much more. The ache is not confined to the head; it's the whole experience. Nausea, sensitivity to light, and throbs so bad it makes simple tasks unbearable. It also comes with an emotional burden—the loneliness and frustration are pretty unbearable. Through the years, realizing how hormones are also implicated in triggering and exacerbating my migraines has helped change the game in my dealing with these episodes.

What are Hormonal Migraines?

Hormonal migraines are caused by fluctuations in estrogen and progesterone, the two main female hormones. These hormones are essential for the reproductive system, regulating menstrual cycles and pregnancy. They also have an effect on brain chemicals, such as serotonin and dopamine, which affect mood and pain perception. When hormone levels fluctuate, such as during menstruation, pregnancy, or menopause, they can destabilize the pathways in the brain, causing migraines.

According to Dr. Shivananda Pai, Consultant Neurology, migraines are more than a neurological disorder. "Migraines represent a complex interplay of genetic, environmental, and hormonal factors. In women, hormonal fluctuations are a critical trigger that amplifies sensitivity to pain," he explains. Hormonal headaches are particularly challenging because they are influenced by multiple life stages, from puberty to post-menopause. Common causes include:

  • Menstrual periods: Estrogen levels significantly drop just before menstruation often triggers a migraine.
  • Pregnancy: Hormones can act to relieve symptoms or aggravate them during different times of pregnancy.
  • Menopause: The hormonal fluctuation during menopause can intensify a migraine, while some women tend to find relief.
  • Hormonal therapies: Birth control and HRT tend to level off hormone balances in some individuals but will exacerbate a migraine in others.

Complex Role of Hormones in Women’s Neurological Health

Estrogen and Neurological Health

Estrogen, often called the "hormone of femininity", does more than regulate reproductive functions. It is a powerful influencer of brain health. Estrogen modulates the activity of neurotransmitters like serotonin, which regulates mood and pain perception, and dopamine, associated with reward and pleasure.

During stages of hormonal stability, like in pregnancy's latter months, women may have fewer migraines because of the steady elevation of estrogen. However, a sudden downfall in estrogen destabilizes these chemicals in the brain, sending a heightened sensitivity for migraine triggers.

Menstrual Migraines

The most common form of hormonal migraines is menstrual migraines, which occur in response to the steep decline in estrogen levels just before menstruation. These are typically more intense and less responsive to standard treatment. The timing of these migraines provides clear evidence of the role hormones play in neurological health.

Pregnancy and Hormonal Shifts

Pregnancy is a rollercoaster of hormones. Although many women experience relief from migraines as a result of the constantly elevated levels of estrogen, some women, particularly in the first trimester, worsen. This individual variability is a characteristic of hormonal migraine triggers.

Hormonal Therapies and Management of Migraine

Hormonal treatments, such as oral contraceptives and HRT, have had mixed reviews regarding their use in managing migraine. Some women fare better with the stabilization the treatment provides, whereas others suffer worsening symptoms. This will depend on the nature and dose of the hormones used.

Post-Menopause: Migraine Remission or Continued Struggles?

For most women, menopause brings relief from their migraines. The decline in frequency and severity often accompanies stability in hormone levels. Even so, the susceptibility remains with some towards other forms of triggers including stress and sleep deprivation, not to forget diet-related factors and continues the saga of migraines well after the menopausal stages.

Effect on Neurological Health Due to Hormonal Changes

The relationship of hormones to neurological health goes beyond migraines. Hormonal changes have profound effects on a woman's brain in general.

Mood Disorders: Estrogen helps stabilize mood by regulating serotonin. Its decline at menopause increases the risk of mood swings and depression.

Neurodegenerative Diseases: Estrogen is neuroprotective, stimulating the growth and repair of brain cells. Its absence in post-menopausal women has been associated with an increased risk of Alzheimer's disease and cognitive decline.

Multiple Sclerosis (MS): Hormonal cycles may affect the course of MS, a disease that occurs more frequently in women than in men. Estrogen's anti-inflammatory effects provide transient protection during pregnancy, reducing relapse rates in women with MS.

"The intricate interplay between hormones and neurological health underscores the need for gender-specific treatment approaches," says Dr. Pai.

Managing Hormonal Migraines: Practical Strategies

While hormonal changes are inevitable, several strategies can help manage migraines effectively:

1. Tracking Your Cycle

Understanding your menstrual cycle can help identify patterns and predict when migraines might occur. This knowledge allows for preventive measures, such as scheduling medications or adjusting lifestyle habits.

2. Consulting Specialists

Working with a neurologist or gynecologist can help develop a personalized treatment plan. Options might include hormonal therapies, triptans, or preventive medications tailored to your specific needs.

3. Adopting a Healthy Lifestyle

A well-balanced diet, regular exercise, and stress management are all integral parts of managing migraines. For instance, magnesium-rich foods and hydration can help reduce the frequency and severity of attacks.

4. Exploring Preventive Therapies

For people with severe or frequent migraines, preventive medications, such as beta-blockers or CGRP inhibitors, may be prescribed. These medications stabilize brain activity and therefore reduce the chances of migraine during hormonal fluctuations.

5. Mind-Body Techniques

Techniques like yoga, meditation, and biofeedback can enhance wellness and reduce the debilitating effects of stress-one of the most common migraine triggers.

Research that was once in its embryonic stage continues to shed more light on the role of hormones in migraines and other neurological conditions. Further breakthroughs in genetic testing might enable doctors to predict, at least in a way, how an individual would react to hormonal therapies. The importance of gender-specific approaches is gradually being realized, which involves differentiating between the plight of women with migraines from others.

As Dr. Pai puts it, "Empowering women with knowledge about the hormonal underpinnings of migraines can lead to better, more personalized care. With the right strategies, migraines can be effectively managed, allowing women to lead fuller, healthier lives.

Migraines are not headaches; they are a complex neurological condition that deeply impacts the lives of millions of women. Understanding the role of hormones in triggering and exacerbating migraines is a vital step toward better management and relief.

Awareness, proactive care, and advances in medical research can help women regain their lives from the grip of hormonal migraines. Whether tracking cycles, adopting healthier habits, or seeking tailored medical care, every step taken toward understanding and managing migraines is a step toward empowerment.

Dr Shivananda Pai is a Consultant Neurology at KMC Hospital Dr B R Ambedkar Circle in Mangalore, India.

Brandes JL. The Influence of Estrogen on Migraine: A Systematic Review. JAMA. 2006;295(15):1824–1830. doi:10.1001/jama.295.15.1824

Sacco S, Ricci S, Degan D, Carolei A. Migraine in women: the role of hormones and their impact on vascular diseases. J Headache Pain. 2012 Apr;13(3):177-89. doi: 10.1007/s10194-012-0424-y. Epub 2012 Feb 26. PMID: 22367631; PMCID: PMC3311830.

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Lung Cancer Symptoms Can Show Up On Your Fingers: Here’s What To Look For

Updated Jan 19, 2026 | 04:04 PM IST

SummaryLung cancer can show early signs beyond a persistent cough or breathlessness. Learn about symptoms that may appear on your fingers and nails, types of lung cancer, and other warning signs to watch for.
lung cancer symptoms on fingers

Credits: Canva

Lung cancer is especially dangerous because its symptoms often do not appear until the harmful cells have already spread through the body. However, there are some early warning signs you might be able to spot. Common indicators include breathlessness, wheezing, and a persistent cough that may bring up blood or mucus. While lung cancer is typically linked to respiratory problems like a chronic cough, shortness of breath, or chest discomfort, experts note that noticeable changes in your fingertips and nails can sometimes serve as early alerts for this potentially serious disease.

What Is Lung Cancer?

Lung cancer is a malignant growth that begins in the tissues of the lungs, usually from DNA damage in the cells lining the airways, which then grow uncontrollably to form tumors. Smoking is a major contributor, but other factors such as exposure to radon, asbestos, or inherited genetic conditions can also play a role.

Symptoms often include a persistent cough, chest pain, and difficulty breathing. Lung cancer is mainly classified into two types: Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC), according to the Cleveland Clinic.

Types Of Lung Cancer

Although many cancers can develop in the lungs, the term “lung cancer” usually refers to two main types: non-small cell and small cell lung cancer.

Non-Small Cell Lung Cancer (NSCLC)

NSCLC is the most common form, accounting for more than 80% of lung cancer cases. Common subtypes include adenocarcinoma and squamous cell carcinoma, while adenosquamous carcinoma and sarcomatoid carcinoma are less frequent forms of NSCLC.

Small Cell Lung Cancer (SCLC)

SCLC tends to grow more quickly and is more challenging to treat than NSCLC. It is often detected as a small tumor that has already spread to other areas of the body. Types of SCLC include small cell carcinoma (also known as oat cell carcinoma) and combined small cell carcinoma.

Lung Cancer Symptom On Fingers

Have you ever pressed your fingernails together and noticed a small diamond-shaped space of light? If that gap is missing, it could be a sign of finger clubbing, a condition where the ends of the fingers swell, which may indicate lung cancer.

This change occurs gradually, starting with the base of the nail becoming soft. Next, the skin around the nail bed may appear shiny, followed by the nails curving more than usual when viewed from the side.

Eventually, the tips of the fingers can enlarge and swell as fluid builds up in the soft tissue. While a missing diamond-shaped gap between your nails doesn’t automatically mean you have lung cancer, it can be a warning sign. If you notice this, it’s wise to consult your doctor.

What Are The Warning Signs Of Lung Cancer?

Lung cancer can present differently in every individual. Some people show multiple symptoms, while others may have none.

Key signs to watch for include:

  • Swelling in the face or neck
  • A cough that changes or worsens
  • Frequent chest infections
  • Shortness of breath
  • Chest or shoulder pain
  • Wheezing
  • Coughing up blood or blood-stained phlegm
  • Hoarseness
  • A persistent cough lasting three weeks or longer
  • Unexplained fatigue or low energy
While these symptoms don’t automatically confirm lung cancer, it is recommended to see your GP if you notice any of these issues.

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Doctor Debunks Five Myths Around Nipah Virus

Updated Jan 19, 2026 | 10:46 AM IST

SummaryWest Bengal has reported five Nipah virus cases in a week, sparking public concern. Doctors warn misinformation fuels unnecessary fear. Nipah is serious but not airborne, always fatal, or untreatable. Early medical care, hygiene, and informed behavior reduce risk. Experts urge calm, fact-based awareness over panic during outbreaks. Read on to know.
Doctor Debunks Five Myths Around Nipah Virus

Credits: Canva

West Bengal is witnessing a Nipah virus outbreak, with five cases of the disease detected in just one week. In an age where information travels faster than verification, fear often fills the gaps left by facts. Each time the Nipah virus makes headlines, anxiety spikes, driven by rumors and alarming social media claims. Doctors say this reaction is understandable but unnecessary. Nipah is a serious illness, but it is not an uncontrollable mystery. Understanding what is true and what is not can help people stay cautious without slipping into panic.

Dr Satya Ranjan Sahu, Senior Consultant in Pulmonology at Narayana Hospital, Gurugram, explains that misinformation can sometimes be more dangerous than the virus itself. Here are some of the most common myths around Nipah virus, and what medical science actually says.

Myth 1: Nipah virus spreads easily through the air

Many people assume Nipah spreads like COVID-19 or seasonal flu. That is not accurate. Nipah does not spread through the air over long distances. Most infections occur after close contact with infected animals or through exposure to bodily fluids of an infected person, such as saliva or respiratory secretions, usually during caregiving. Human-to-human transmission is possible, but it typically requires prolonged and unprotected close contact.

Also Read: Nipah Virus Case Detected In Two Nurses From West Bengal

Myth 2: Getting infected always leads to death

The severity of Nipah has led to the belief that infection equals death. Doctors strongly refute this. While Nipah can be life-threatening, not every case is fatal. Many patients recover, especially when the infection is identified early and medical care begins promptly. Early diagnosis, hospital monitoring, and supportive treatment can significantly improve outcomes.

Myth 3: There is no treatment, so nothing can help

It is true that there is no specific antiviral drug approved to cure Nipah virus. However, this does not mean patients cannot be treated. Medical care focuses on managing symptoms, supporting breathing, maintaining hydration, and preventing complications. With proper hospital care, patients can be stabilised and supported through the illness. Calling Nipah untreatable often discourages people from seeking timely medical help, which can be dangerous.

Myth 4: Without a vaccine, prevention is impossible

The absence of a vaccine can make people feel helpless, but prevention does not depend on vaccines alone. Simple steps are highly effective. Maintaining good hygiene, avoiding contact with sick animals, using protective gear while caring for infected individuals, and following public health advisories all reduce risk. Doctors stress that informed and cautious behavior remains one of the strongest tools against Nipah.

Read: Unique Symptoms Of Nipah Virus Found In West Bengal And How Long Infection Now Last

Myth 5: All fruits are unsafe to eat

Fruit bats are natural carriers of the Nipah virus, which has led to widespread fear around fruit consumption. Doctors clarify that fruits are not automatically dangerous. Properly washed, peeled, and hygienically handled fruits are generally safe to eat. Most human infections have been linked to close contact with infected animals or people, not routine fruit consumption.

What doctors want people to remember

Nipah virus is serious, but it is not as easily spread or as hopeless as many believe. Early symptoms may include fever, headache, muscle pain, or vomiting, and in some cases progress to breathing or neurological problems. Seeking medical care at the first sign of symptoms can save lives. Health experts urge the public to rely on verified information from trusted medical sources and avoid spreading unconfirmed claims.

During outbreaks, calm awareness matters. Separating myths from medical facts allows communities to respond with care, responsibility, and confidence rather than fear.

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Measles Symptoms Explained: Can The Infection Be Deadly?

Updated Jan 18, 2026 | 08:09 PM IST

SummaryMeasles cases in the US have reached a 33-year high. Here’s what to know about measles symptoms, how dangerous it can be, and what treatment options are available. Keep reading for details.
measles symptoms

Credits: Canva

As measles continues to spread across the United States, with recent case numbers climbing to their highest level in 33 years, growing numbers of Americans are becoming concerned about how at risk they may be.

Health officials in Philadelphia confirmed a potential measles exposure at Philadelphia International Airport and several public transport locations across the city in early January. The Centers for Disease Control and Prevention has also flagged earlier measles outbreaks across Pennsylvania, New Jersey, and New York City.

Adding to the concern, infectious disease tracker BMJGroup reported that measles cases recorded in 2025 are the highest seen since at least 1992.

Against this backdrop, it is important to understand whether measles can be fatal and to recognise the symptoms that should not be ignored.

Is Measles Deadly?

Yes, measles can be deadly and carries a significant risk of death, according to the Centers for Disease Control and Prevention.

“Measles can lead to serious health complications, including pneumonia, inflammation of the brain known as encephalitis, and death,” the CDC states. “Between one and three out of every 1,000 people infected with measles will die. Around one in five people with measles will require hospital care, and one in every 20 children with measles develops pneumonia, which is the leading cause of measles-related deaths in young children.

“One in every 1,000 people with measles will experience brain swelling, which can result in permanent brain damage.”

Measles Symptoms Develop In Three Stages

According to the Mayo Clinic, measles symptoms usually appear in three distinct stages.

Stage 1: Incubation period (10 to 14 days)

During this phase, there are typically no noticeable or warning symptoms.

Stage 2: Early symptoms begin

Symptoms at this stage may include a dry cough, fever, red and inflamed eyes known as conjunctivitis, a runny nose, and a sore throat.

Stage 3: Acute illness and rash

“In the third stage, a rash begins to develop, usually starting on the face. Small white spots called Koplik spots may appear inside the mouth two to three days after symptoms first appear,” the Mayo Clinic explains. “The measles rash typically shows up three to five days after the initial symptoms.

“Over the following days, the rash spreads to the arms, torso, and legs. Alongside the rash, fever often rises rapidly and can exceed 105 degrees Fahrenheit,” the guidance continues. “Eventually, the fever subsides, and the rash fades from the body starting at the head and moving downward.”

How Do You Treat Measles?

There is no specific antiviral medication that cures measles. However, people who have not previously been vaccinated may still be able to reduce the severity of illness if action is taken quickly after exposure.

“If individuals aged six months or older are exposed to measles and do not have immunity from prior infection or vaccination, they can receive the measles vaccine within three days of contact with the virus,” the Mayo Clinic advises. “After vaccination, quarantine at home is not required.

“For children up to 11 months old who are exposed and are not immune, a dose of antibodies known as immune globulin can be given within six days of exposure to help the body fight the infection.”

Receiving this antibody treatment requires a 21-day quarantine period.

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