When was the last time you measured your waistline? If you assume that BMI is the only number to focus on when it comes to your health, think twice. New research has revealed a shocking revelation—your waist circumference might be a far better predictor of men's cancer risk than BMI.

The study finds that for each 4-inch increase in waist size, a man's risk of cancer increases by a staggering 25%. Meanwhile, BMI, commonly regarded as the gold standard for assessing obesity, raises cancer risk by only 19% for the same weight gain. So, if you've been dismissing that pesky belly fat, it's time to take notice.

But why is your waistline so important? The reason is visceral fat—the hidden, deep fat that accumulates around your organs. Unlike other body fat, visceral fat is a stealthy troublemaker, causing inflammation, insulin resistance, and abnormal blood fat levels—all of which combine to create a cancer-perfect storm.

Obesity has been associated with an increased risk of numerous health conditions, including cancer, for decades. The research, though, indicates that a specific measure of the body—waist circumference—may be an even more reliable forecaster of cancer risk in men than the more frequently employed Body Mass Index (BMI). This finding emphasizes the need to pay particular attention to the distribution of fat and not merely to the weight of the body.

BMI has been the go-to measure for years for gauging health risks related to obesity. New research, though, that appears in The Journal of the National Cancer Institute indicates that waist measurement is a better predictor of cancer risk in men. According to the research, four more inches (10 cm) around the waist will add 25% to a man's cancer risk. Conversely, a 3.7 kg/m² rise in BMI (from a BMI of 24 to 27.7) increased cancer risk by only 19%.

Why is waist circumference a better predictor, then? Unlike BMI, which measures weight relative to height, waist circumference actually measures abdominal fat—specifically, visceral fat. This type of fat encircles internal organs and is also linked to higher levels of inflammation, insulin resistance, and abnormal blood lipids, all of which are factors in cancer growth. BMI, however, does not measure fat distribution, so two individuals with the same BMI can have very different levels of health risk depending on where fat is deposited on their bodies.

Why Men Are at Higher Risk?

Interestingly, the research identified a significant difference between men and women when it came to waist circumference and cancer risk. Although waist circumference and BMI were linked with obesity-related cancers in women, the relationship was weaker than for men. An increase of 12 cm (4.7 inches) in waist size or a 4.3 rise in BMI (from 24 to 28.3) raised the cancer risk in women by just 13%—a much lower percentage than for men.

Experts credit this difference to the way that fat is stored in the body. Men are more likely to carry fat around the abdomen, especially as visceral fat, which is more metabolically active and associated with cancer-producing biological alterations. Women, by contrast, store fat in peripheral sites such as the hips and thighs, where it is less likely to drive systemic inflammation and metabolic disturbances.

A possible reason is that men tend to depot fat more in the visceral regions, whereas women tend to carry more subcutaneous and peripheral fat," wrote the researchers. "This may render waist circumference a more robust risk factor for cancer in men and account for why waist circumference provides additional risk information beyond BMI in men but not women."

Cancer Types Most Linked to Abdominal Fat

The research used the International Agency for Research on Cancer (IARC) data to define obesity-related cancers. These cancers are esophageal (adenocarcinoma), gastric (cardia), colorectal, rectal, liver, gallbladder, pancreatic, renal, and thyroid cancers, and multiple myeloma and meningioma. In men, abdominal obesity is especially significant in raising the risk of these cancers through high levels of insulin and markers of inflammation.

For women, the research proposes that both waist circumference and hip circumference may give a more accurate estimate of visceral fat and cancer risk. "Adding hip circumference to risk models could strengthen the link between waist circumference and cancer, especially in women," researchers observed.

What This Means for Men's Health and Cancer Prevention?

With these results, doctors advise men to be more mindful of their waistline than only their BMI. Waist size is an easy method to gauge health risk, and its maintenance through lifestyle changes might be the key to cancer prevention.

How To Reduce Cancer Risk In Men?

Track Your Waist Size: Regularly measure your waist circumference and try to keep it in a healthy range (below 40 inches for men, according to medical advice).

Eat a Balanced Diet: A diet containing high fiber, lean protein, and healthy fats can assist in limiting visceral fat gain.

Exercise Consistently: Regular exercise with a combination of aerobic and strength training will help maintain a healthy waistline.

Control Stress and Sleep: Persistent stress and inadequate sleep tend to cause weight gain, especially in the midsection of the body.

Regular Health Screenings: Early identification of cancer risk factors through regular screening can greatly enhance long-term health status.

A newly identified flu strain that spreads easily and causes more severe illness is driving infections this season. The strain, a mutated form of influenza A H3N2 known as subclade K, has been linked to a growing number of cases worldwide, including across the United States.

According to the World Health Organization, the K variant represents “a notable evolution in influenza A (H3N2) viruses,” prompting concerns among experts about how well this season’s flu vaccine may work against it.

Health specialists say the K variant is associated with stronger flu symptoms such as fever, chills, headaches, exhaustion, cough, sore throat, and a runny nose. A CDC report found that of the 216 influenza A(H3N2) samples collected since September 28, nearly 90 percent were identified as subclade K. As this strain continues to circulate, here is a closer look at the symptoms being reported and the areas where flu activity is currently highest.

New Flu Symptoms

Doctors say the symptoms caused by the mutated H3N2 strain closely resemble those of typical seasonal influenza A. Common symptoms include:

• Fever
• Chills
• Body aches
• Headache
• Severe fatigue
• Nasal congestion or a runny nose
• Cough

Flu symptoms often come on abruptly, Hopkins explains, describing it as a sudden, overwhelming feeling of being unwell.

The CDC notes that flu symptoms can overlap with those of COVID-19 and other respiratory viruses, making testing important. Three-in-one rapid home tests that check for influenza A, influenza B, and COVID-19 are now available, and experts advise keeping them on hand when possible. If you test positive for the flu, antiviral medications may help shorten the illness and lessen symptom severity, Hopkins adds.

Flu Shots: Where Is Subclade K Spreading In The US?

Below are the states and regions reporting the highest levels of medical visits related to flu-like illness, which may not reflect confirmed flu cases. The data reflects CDC reporting for the week ending December 25.

Very High (Level 1)

• New York City

Very High (Level 2)

• New York State

Very High (Level 3)

• New Jersey
• Rhode Island
• Louisiana
• Colorado

High (Level 1)

• Massachusetts
• Connecticut
• Michigan
• Idaho
• South Carolina

High (Level 2)

• New Mexico

High (Level 3)

• Washington, D.C.
• Maryland
• North Carolina
• Georgia

The CDC estimates that the flu has already caused at least 4.6 million illnesses, 49,000 hospitalizations, and 1,900 deaths so far this season. Health officials continue to recommend the flu vaccine as the most effective way to reduce the risk of serious illness.

Super Flu Symptoms: How to Protect Yourself From the Flu

During peak respiratory virus season, experts advise taking basic precautions to lower your risk and protect others:

• Keep vaccinations up to date.
• Get tested if symptoms appear.
• If you test positive, stay home until you are fever-free for 24 hours without medication and your symptoms are improving. If you do not have a fever, remain home for five days after symptoms begin.
• Avoid close contact with people who are sick.
• Wear a mask in crowded indoor settings.
• Wash your hands often.
• Cover your mouth and nose when coughing or sneezing.

Tramadol: A broad review of previously published studies suggests that tramadol, a powerful opioid often prescribed for long-term pain, provides only modest pain relief for the conditions it is most commonly used to treat. The conclusions come from a combined analysis of existing research, published online in BMJ Evidence-Based Medicine.

The review also highlights a greater risk of serious side effects, including heart-related problems. In light of these findings, the researchers say tramadol’s potential harms are likely to outweigh its benefits and advise that its use should be scaled back.

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What Is Tramadol?

Tramadol is a dual-mechanism opioid prescribed for moderate to severe pain, both short-term and long-lasting. For this reason, it features in several medical guidelines as an option for pain control, the researchers note. Prescriptions for tramadol have increased sharply over the past few years, making it one of the most widely used opioids in the United States.

This rise may be linked to the belief that tramadol causes fewer side effects and carries a lower risk of dependence than other fast-acting opioids. Although earlier systematic reviews have looked at tramadol, the researchers point out that no previous review has fully assessed both its effectiveness and safety across a wide range of chronic pain conditions.

Tramadol: Why Are Scientists Cautioning Against Tramadol Use?

According to Scitech Daily, the research team searched medical databases for randomized clinical trials published up to February 2025. These studies compared tramadol with a placebo, or dummy treatment, in people living with chronic pain, including cancer-related pain.

Nineteen clinical trials involving 6,506 participants with chronic pain met the criteria for inclusion. Five studies examined tramadol’s effect on nerve pain; nine focused on osteoarthritis; four assessed chronic lower back pain; and one looked at fibromyalgia. Eight trials also reported the rate of serious side effects during follow-up periods ranging from seven to sixteen weeks.

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Statistical analysis showed that tramadol was linked to about twice the risk of harm compared with placebo. This increase was largely driven by a higher number of cardiac events, including chest pain, coronary artery disease, and congestive heart failure. Tramadol use was also associated with a greater risk of certain cancers, although the researchers describe this finding as “questionable” due to the short follow-up period.

When all trial data were pooled, tramadol treatment was also tied to a higher likelihood of less severe side effects such as nausea, dizziness, constipation, and drowsiness. The researchers acknowledge that the study outcomes carried a high risk of bias. However, they add that this likely means the benefits of tramadol may be overstated while its risks could be underestimated.

Tramadol Side Effects

According to the NHS, like most medicines, tramadol can cause side effects, although not everyone experiences them. You should speak to your doctor or pharmacist if any of the side effects listed below trouble you or persist.

• Very common side effects
• Very common side effects affect more than 1 in 10 people and include:
• feeling sick
• feeling dizzy

Tramadol: Common Side Effects

These occur in more than 1 in 100 people. There are steps that can help manage them.

• headaches
• feeling sleepy, tired, dizzy, or “spaced out”
• nausea or vomiting
• constipation
• dry mouth
• sweating
• low energy

Tramadol: Serious Side Effects

Serious side effects affect fewer than 1 in 100 people.

Call your doctor or contact 111 immediately if you:

• feel dizzy, tired, and unusually low on energy, which may signal low blood pressure
• experience hallucinations, such as seeing or hearing things that are not there
• feel confused
• feel extremely sleepy
• have difficulty passing urine or are unable to urinate

Does Tramadol Lower Blood Pressure?

Yes, tramadol can cause a drop in blood pressure, known as hypotension, particularly when standing up suddenly. This can lead to dizziness or fainting, although it is not very common. In rare cases, tramadol may also raise blood pressure, and stopping the drug suddenly can trigger a spike in blood pressure. For these reasons, anyone with concerns about blood pressure should discuss them with their doctor, according to the NHS.

Waking up with a sore, scratchy throat can feel like a dry-air problem, especially during colder months. In reality, it is often one of the first signs that your immune system has started responding to a viral infection.

What Can Cause Throat Discomfort?

Throat discomfort is often the earliest symptom because viruses tend to attach themselves to this area first, explained Benjamin C. Tweel, an assistant professor of otolaryngology at the Icahn School of Medicine at Mount Sinai, as per The Washington Post.

“The virus enters the cells that line the throat, which likely triggers an inflammatory response from the immune system,” said Tweel, who also serves as medical director for the department of otolaryngology at Mount Sinai Health System. Once the body detects the virus, lymphatic tissue at the back of the nose and throat becomes swollen and inflamed, leading to pain, experts noted.

“Sometimes your body manages to fight it off before it turns into anything major,” Mock said. In other cases, familiar upper respiratory symptoms soon follow, such as a runny nose, nasal congestion and coughing.

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Home Remedies For Sore Throat

According to the Centers for Disease Control and Prevention, throat pain linked to an upper respiratory infection usually improves within about a week. Over-the-counter pain relievers like ibuprofen or naproxen can help ease discomfort and may be more effective than acetaminophen because they reduce both pain and inflammation, Tweel said. Alongside medication, certain home remedies may also provide relief. Here are some options worth trying.

Saltwater Gargle

Gargling with salt water has long been recommended for sore throats, and limited research suggests it may help. A small randomized controlled trial published in 2019 in the Journal of Complementary and Alternative Medical Research found that people with nonbacterial sore throats who used saltwater gargles reported less pain and less difficulty swallowing after one week compared with those who used a thymol-based antiseptic mouthwash.

Salt may help by reducing swelling in throat tissue, said Cameron Wick, an otologist and neurotologist at University Hospitals. “This is basic osmosis,” he explained. “Some of the fluid inside the throat tissue moves into the salt solution, which can lessen inflammation.” Saltwater gargling may also help clear away debris and viral particles, Tweel added.

While the evidence is limited, saline gargles are unlikely to cause harm, Mock said. “It might offer a small benefit, and it is generally safe.” Wick recommends mixing 1 teaspoon of salt into 8 ounces of warm water. Saltwater rinses may also help with thick mucus, nasal congestion or allergy symptoms. Wick said over-the-counter saline sprays or nasal irrigation devices can help clear nasal passages, improve breathing, hydrate tissues and reduce swelling.

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When using nasal irrigation devices, only distilled, sterile or boiled and cooled water should be used. Tap water can contain microorganisms that are unsafe if they enter the sinuses.

Honey

Honey is known for its antibacterial properties, Wick said, and its thick texture can coat and protect irritated throat tissue. “It feels soothing on mucosal surfaces,” he explained. By forming a barrier, honey may reduce irritation from air, liquids and swallowing.

Some research supports honey for easing symptoms of upper respiratory infections, including sore throat and cough. A small study published in 2023 found that gargling with a mixture of honey and water helped reduce throat pain after tonsillectomy surgery.

Honey can also be helpful for children over the age of 1 who have sore throats or coughs. The American Academy of Pediatrics recommends honey over many over-the-counter cold medicines for young children, as those products offer limited benefit. “For kids older than 1, a teaspoon of honey or honey mixed into warm liquid can help soothe the throat and improve sleep,” Mock said. Honey should never be given to infants under 12 months due to the risk of infant botulism.

Tea

Warm tea can feel comforting on a sore throat, but not all teas are ideal during an infection. “Stick to non-caffeinated options,” Wick advised. Black teas and other strong, tannin-rich teas often contain caffeine, which can increase urine output and contribute to dehydration.

There is limited research on herbal teas for throat pain, but chamomile, ginger and turmeric are commonly recommended, Wick said.

Adding honey and lemon can enhance tea’s soothing effects. Lemon provides vitamin C, which supports immune function, and stimulates saliva production, Wick explained. Increased saliva can help thin mucus and support the many small glands beneath the throat’s surface, making it easier for the body to manage congestion.

Warm Beverages

If tea is not your preference, other warm drinks such as warm water, vegetable broth, bone broth or soup may provide similar comfort. “Warm liquids have a calming effect,” Wick said.

These beverages may also encourage better hydration, which is important for recovery. “Staying hydrated is one of the most helpful things you can do for a sore throat,” Tweel said. Dryness tends to worsen throat pain. Soup can also be soothing, as long as it does not contain ingredients that irritate the throat, Mock added.

Cool Foods

Some people find relief from cold items like ice chips or ice pops, especially when throat pain is more intense, Wick said. After tonsil removal surgery, children are often encouraged to eat ice cream or popsicles because cold temperatures can calm pain-sensitive nerve endings.

There is little research specifically on cold foods for sore throats caused by infections, but cooling therapies have been shown to reduce throat discomfort after medical procedures such as surgery or intubation.

Using A Humidifier

Dry air can worsen irritation in the nose, mouth and throat. “This helps explain why people often feel worse after flying,” Tweel said. A cool-mist humidifier or vaporizer can reduce dryness and ease scratchiness.

However, these devices must be cleaned carefully. “I personally avoid them because proper sanitation can be difficult,” Tweel said. Mold and bacteria can grow in humidifiers, and inhaling contaminated mist may increase the risk of illness.

The CDC advises cleaning humidifiers according to manufacturer guidelines, emptying water tanks daily, and using distilled or boiled and cooled water to reduce microbial growth.

If maintaining a humidifier feels overwhelming, steam from a hot shower or from a cup of hot tea or boiling water may offer similar benefits, Tweel said.

Lozenges

For adults, lozenges or cough drops can stimulate saliva production, which helps combat dryness, Tweel said. “A lot of throat soreness comes from being dry or dehydrated,” he explained. Increasing moisture can make a noticeable difference.

There are many lozenge options available, and choosing what feels soothing is reasonable. Some people prefer lozenges with menthol or eucalyptus for their cooling sensation. Lozenges and cough drops should not be given to children under 4 years old due to choking risks.

When To See Your Doctor For A Sore Throat

Most sore throats improve after a few days, Mock said, often followed by nasal symptoms and then a chest cough. “That pattern is typical for a viral upper respiratory infection,” she said. As long as symptoms are improving and not worsening, the illness usually resolves within one to two weeks.

Medical care may be needed in certain situations. You should contact your primary care provider if throat pain is accompanied by fever, severe pain, difficulty breathing or swallowing, white patches at the back of the throat, or noticeable differences in tonsil size, Wick said. These signs may point to a bacterial infection such as strep throat, which may require antibiotics.

Persistent throat pain should also be evaluated. “A severe sore throat lasting more than seven days is not normal,” Mock said. “By that point, it should be improving.”