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When was the last time you measured your waistline? If you assume that BMI is the only number to focus on when it comes to your health, think twice. New research has revealed a shocking revelation—your waist circumference might be a far better predictor of men's cancer risk than BMI.
The study finds that for each 4-inch increase in waist size, a man's risk of cancer increases by a staggering 25%. Meanwhile, BMI, commonly regarded as the gold standard for assessing obesity, raises cancer risk by only 19% for the same weight gain. So, if you've been dismissing that pesky belly fat, it's time to take notice.
But why is your waistline so important? The reason is visceral fat—the hidden, deep fat that accumulates around your organs. Unlike other body fat, visceral fat is a stealthy troublemaker, causing inflammation, insulin resistance, and abnormal blood fat levels—all of which combine to create a cancer-perfect storm.
Obesity has been associated with an increased risk of numerous health conditions, including cancer, for decades. The research, though, indicates that a specific measure of the body—waist circumference—may be an even more reliable forecaster of cancer risk in men than the more frequently employed Body Mass Index (BMI). This finding emphasizes the need to pay particular attention to the distribution of fat and not merely to the weight of the body.
BMI has been the go-to measure for years for gauging health risks related to obesity. New research, though, that appears in The Journal of the National Cancer Institute indicates that waist measurement is a better predictor of cancer risk in men. According to the research, four more inches (10 cm) around the waist will add 25% to a man's cancer risk. Conversely, a 3.7 kg/m² rise in BMI (from a BMI of 24 to 27.7) increased cancer risk by only 19%.
Why is waist circumference a better predictor, then? Unlike BMI, which measures weight relative to height, waist circumference actually measures abdominal fat—specifically, visceral fat. This type of fat encircles internal organs and is also linked to higher levels of inflammation, insulin resistance, and abnormal blood lipids, all of which are factors in cancer growth. BMI, however, does not measure fat distribution, so two individuals with the same BMI can have very different levels of health risk depending on where fat is deposited on their bodies.
Interestingly, the research identified a significant difference between men and women when it came to waist circumference and cancer risk. Although waist circumference and BMI were linked with obesity-related cancers in women, the relationship was weaker than for men. An increase of 12 cm (4.7 inches) in waist size or a 4.3 rise in BMI (from 24 to 28.3) raised the cancer risk in women by just 13%—a much lower percentage than for men.
Experts credit this difference to the way that fat is stored in the body. Men are more likely to carry fat around the abdomen, especially as visceral fat, which is more metabolically active and associated with cancer-producing biological alterations. Women, by contrast, store fat in peripheral sites such as the hips and thighs, where it is less likely to drive systemic inflammation and metabolic disturbances.
A possible reason is that men tend to depot fat more in the visceral regions, whereas women tend to carry more subcutaneous and peripheral fat," wrote the researchers. "This may render waist circumference a more robust risk factor for cancer in men and account for why waist circumference provides additional risk information beyond BMI in men but not women."
The research used the International Agency for Research on Cancer (IARC) data to define obesity-related cancers. These cancers are esophageal (adenocarcinoma), gastric (cardia), colorectal, rectal, liver, gallbladder, pancreatic, renal, and thyroid cancers, and multiple myeloma and meningioma. In men, abdominal obesity is especially significant in raising the risk of these cancers through high levels of insulin and markers of inflammation.
For women, the research proposes that both waist circumference and hip circumference may give a more accurate estimate of visceral fat and cancer risk. "Adding hip circumference to risk models could strengthen the link between waist circumference and cancer, especially in women," researchers observed.
With these results, doctors advise men to be more mindful of their waistline than only their BMI. Waist size is an easy method to gauge health risk, and its maintenance through lifestyle changes might be the key to cancer prevention.
Track Your Waist Size: Regularly measure your waist circumference and try to keep it in a healthy range (below 40 inches for men, according to medical advice).
Eat a Balanced Diet: A diet containing high fiber, lean protein, and healthy fats can assist in limiting visceral fat gain.
Exercise Consistently: Regular exercise with a combination of aerobic and strength training will help maintain a healthy waistline.
Control Stress and Sleep: Persistent stress and inadequate sleep tend to cause weight gain, especially in the midsection of the body.
Regular Health Screenings: Early identification of cancer risk factors through regular screening can greatly enhance long-term health status.
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A mammogram is routinely used to detect early signs of breast cancer, but the imaging test may also provide clues about a woman’s cardiovascular health.
Cardiovascular disease is a major cause of death among women. Yet, experts say heart disease in women can be overlooked because symptoms and risk factors may differ from the patterns traditionally associated with men.
Prof Rob Galloway of University Hospitals Sussex NHS Foundation Trust, writing in the Daily Mail, highlighted the need to identify cardiovascular disease in women earlier.
Citing a 2021 The Lancet study, he noted that women with cardiovascular disease remain “understudied, under-recognized, underdiagnosed, and undertreated.”
Galloway said he regularly sees women, particularly those in their 60s, arriving in emergency care with heart attacks after earlier symptoms were attributed to less serious causes.
“If that had been recognized, she could have been admitted, and if needed, had a stent (a mesh tube) inserted to open the artery before it was blocked,” he wrote.
“The truth is doctors are not as good as we should be at recognizing heart disease in women, or understanding their risk,” he added.
Women may experience heart attacks differently, with symptoms such as breathlessness, nausea, fatigue, or back, neck and jaw pain. Galloway also highlighted female-specific risk factors, which include:
He said these factors are not always routinely included when assessing a woman’s long-term cardiovascular risk.
Prof Galloway suggested that routine breast screening could potentially offer another opportunity to identify cardiovascular risk.
When blood vessels are damaged, calcium can accumulate in their walls. Mammograms can sometimes detect calcium deposits in the arteries of the breast, known as breast arterial calcification (BAC).
BAC is different from calcium buildup in the coronary arteries, but its presence has been associated with a higher risk of cardiovascular events such as heart attack and stroke. Some radiologists may therefore flag the finding to the treating doctor.
Prof Galloway also discussed the potential role of artificial intelligence in identifying and measuring breast arterial calcification.
A European Heart Journal study used AI to assess mammograms from over 123,500 US women. Compared with no calcification, mild breast arterial calcification was linked to a 30% higher cardiovascular event risk, moderate to 75–80% higher risk, and severe to roughly three times higher risk.
The association persisted even after researchers accounted for established cardiovascular risk factors such as obesity and smoking.
Prof Galloway said that the potential advantage is that the mammogram has already been performed for breast screening. If arterial calcification is identified, that information could potentially be included with the screening result and prompt a broader cardiovascular risk assessment.
Depending on the woman's overall risk, doctors could then consider measures such as more intensive management of blood pressure or cholesterol.
A coronary artery calcium scan is another way to assess calcium buildup in the arteries supplying the heart. It uses a CT scan to detect and measure coronary artery calcium and can help inform cardiovascular risk assessment in appropriate patients.
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There are many patients with CKD and CKD touches more than just the kidneys. CKD also influences parts of the body and as kidney function falls changes in the body can affect the brain. This may raise the chance of memory problems trouble concentrating and other types of impairment. For people living with CKD, those whose disease is advanced protecting cognitive health can become an important part of overall care.
CKD can arise from causes with diabetes as a leading one. In some groups diabetes accounts for than half of CKD cases. When diabetes meets CKD, the risk of vascular disease rises. This disease builds fatty deposits inside blood vessels. If those vessels feed the brain blood flow can drop. Reduced brain blood flow can lead to problems and raise the risk of dementia.
Another important factor is the build‑up of waste in the blood. Healthy kidneys waste and excess substances. When CKD lowers kidney function these substances linger. The lingering waste can disturb brain function. Symptoms may include trouble paying attention, slower thinking, confusion or memory problems.
Electrolyte disturbances can also play a role especially when CKD changes the balance of minerals in the body.
Hyponatremia or abnormally low levels of sodium in the blood is relatively common in people with CKD. It can disturb brain function.
Depending on severity and how fast it appears hyponatremia can cause confusion, difficulty concentrating, drowsiness and in cases more serious neurological symptoms.
Also read: Diabetes Linked To 55% Risk Of Kidney Disease, Heart Failure Or Death Within 10 Years: Study
Treatment‑related factors may also be relevant for some patients.
In the past dialysis patients who received aluminium‑containing medicines, such as some antacids or phosphate‑binding preparations faced a risk of aluminium build‑up. High levels of aluminium were linked to problems, including cognitive impairment. Today dialysis practices and medicines have cut this risk dramatically so aluminium is now an issue rather than a common cause of cognitive problems in dialysis patients.
As CKD moves forward into advanced stages the risk of cognitive impairment grows. Many factors can act together: disease, metabolic and electrolyte changes, anaemia, inflammation, heart complications and the build‑up of toxins that healthy kidneys would normally flush away.
Not every person with CKD will develop dementia. Cognitive changes should not be brushed off as normal ageing. New problems, with memory, concentration orientation or daily tasks need to be talked about with a doctor.
Early recognition is important because some of these factors can be treated or reversed.
Keeping diabetes and blood pressure under control managing heart risk factors correcting electrolyte imbalances and getting kidney care all help protect both kidney and brain health.
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Plastics are everywhere today. It is woven into our clothes, tucked into children's toys, used in food containers, and found in almost every household products. A new analysis has raised concerns about the chemicals used to make these products and the health hazards due to constant exposure.
According to an investigation reported by CNN, nearly 93% of known plastic chemicals used in everyday products were classified as posing a high risk to human health. The analysis looked at plastics used in food-contact materials, toys, clothing and textiles, household products, and hygiene and medical products.
The findings highlight how widespread exposure to hazardous chemicals can affect our health and how much remains unknown about their long-term effects.
A researcher at Environmental Justice Foundation, Naima Fenderl’s Poison Plastics: How Chemicals in Everyday Plastics are Harming Your Health released recently and revealed astounding facts about plastic chemicals.
She said, “We looked at what these plastic chemicals can do to the body along with exposure levels to calculate overall health risk.” The analysis found that:
The chemicals are not necessarily the plastic itself. Many are additives that are used to make plastics flexible, durable, heat-resistant, or less likely to catch fire.
Also read: Botox And Fillers: UK Watchdog Says Clinics Should Check Mental Health Before Injecting
Some plastic chemicals have been linked to cancer, genetic changes and problems affecting the hormonal, reproductive and organ systems. Among the chemicals of concern are bisphenols, phthalates, and PFAS, which can be used in different plastic products.
Some of these chemicals can interfere with the body's endocrine system, which controls hormones involved in metabolism, reproduction, growth, and development.
The concern is important for children and during pregnancy because hormonal systems and organ development may be more vulnerable to certain chemical exposures.
The report also highlighted the challenge of lack of sufficient data to certainly assess health risks posed by these plastic chemicals. Almost 80% of the 3,552 chemicals in plastics people often use everyday lacked sufficient data to understand health risks.
“We simply do not have a clue what harm those chemicals might be causing us and our kids,” Dr. Philip Landrigan, director of the Global Observatory on Planetary Health and the Program for Global Public Health and the Common Good at Boston College told CNN.
He added, “We don’t even know the names or composition of a lot of the chemicals that are in consumer products — the chemical industry presumably has that information, but it’s not publicly available.”
Chemical exposure is only one part of the plastic problem. Tiny plastic particles, known as microplastics, and even smaller nanoplastics, can also enter our bodies through food and water.
University of Columbia released an analysis of plastic bottled water based on a laser-based highly sensitive imaging technique. It found an average of around 240,000 plastic particles per litre, with most nanoplastics.
These particles can come from the bottle, the cap, manufacturing, and handling. Opening and closing the bottle repeatedly can also create friction between the cap and bottle neck, releasing tiny plastic fragments.
Larger particles are generally expected to pass through the digestive system. But nanoplastics are small enough to cross biological barriers.
Research has found that plastic particles can reach the circulatory system and other tissues, but scientists still do not know exactly which particles cross these barriers most easily, how much accumulates in the body or what level of exposure causes harm.
Quitting using plastic entirely is not practical for most people. Instead, reducing avoidable exposure could be a sensible approach.
Avoid heating food in plastic containers, particularly when the container is not designed for high temperatures. Using glass or stainless steel for hot food and drinks can also reduce reliance on plastic food-contact materials.
Filtration or boiling of drinking water may help reduce some microplastics. But doctors believe that heat may only alter some plastic particles, not destroy them completely.
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