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When was the last time you measured your waistline? If you assume that BMI is the only number to focus on when it comes to your health, think twice. New research has revealed a shocking revelation—your waist circumference might be a far better predictor of men's cancer risk than BMI.
The study finds that for each 4-inch increase in waist size, a man's risk of cancer increases by a staggering 25%. Meanwhile, BMI, commonly regarded as the gold standard for assessing obesity, raises cancer risk by only 19% for the same weight gain. So, if you've been dismissing that pesky belly fat, it's time to take notice.
But why is your waistline so important? The reason is visceral fat—the hidden, deep fat that accumulates around your organs. Unlike other body fat, visceral fat is a stealthy troublemaker, causing inflammation, insulin resistance, and abnormal blood fat levels—all of which combine to create a cancer-perfect storm.
Obesity has been associated with an increased risk of numerous health conditions, including cancer, for decades. The research, though, indicates that a specific measure of the body—waist circumference—may be an even more reliable forecaster of cancer risk in men than the more frequently employed Body Mass Index (BMI). This finding emphasizes the need to pay particular attention to the distribution of fat and not merely to the weight of the body.
BMI has been the go-to measure for years for gauging health risks related to obesity. New research, though, that appears in The Journal of the National Cancer Institute indicates that waist measurement is a better predictor of cancer risk in men. According to the research, four more inches (10 cm) around the waist will add 25% to a man's cancer risk. Conversely, a 3.7 kg/m² rise in BMI (from a BMI of 24 to 27.7) increased cancer risk by only 19%.
Why is waist circumference a better predictor, then? Unlike BMI, which measures weight relative to height, waist circumference actually measures abdominal fat—specifically, visceral fat. This type of fat encircles internal organs and is also linked to higher levels of inflammation, insulin resistance, and abnormal blood lipids, all of which are factors in cancer growth. BMI, however, does not measure fat distribution, so two individuals with the same BMI can have very different levels of health risk depending on where fat is deposited on their bodies.
Interestingly, the research identified a significant difference between men and women when it came to waist circumference and cancer risk. Although waist circumference and BMI were linked with obesity-related cancers in women, the relationship was weaker than for men. An increase of 12 cm (4.7 inches) in waist size or a 4.3 rise in BMI (from 24 to 28.3) raised the cancer risk in women by just 13%—a much lower percentage than for men.
Experts credit this difference to the way that fat is stored in the body. Men are more likely to carry fat around the abdomen, especially as visceral fat, which is more metabolically active and associated with cancer-producing biological alterations. Women, by contrast, store fat in peripheral sites such as the hips and thighs, where it is less likely to drive systemic inflammation and metabolic disturbances.
A possible reason is that men tend to depot fat more in the visceral regions, whereas women tend to carry more subcutaneous and peripheral fat," wrote the researchers. "This may render waist circumference a more robust risk factor for cancer in men and account for why waist circumference provides additional risk information beyond BMI in men but not women."
The research used the International Agency for Research on Cancer (IARC) data to define obesity-related cancers. These cancers are esophageal (adenocarcinoma), gastric (cardia), colorectal, rectal, liver, gallbladder, pancreatic, renal, and thyroid cancers, and multiple myeloma and meningioma. In men, abdominal obesity is especially significant in raising the risk of these cancers through high levels of insulin and markers of inflammation.
For women, the research proposes that both waist circumference and hip circumference may give a more accurate estimate of visceral fat and cancer risk. "Adding hip circumference to risk models could strengthen the link between waist circumference and cancer, especially in women," researchers observed.
With these results, doctors advise men to be more mindful of their waistline than only their BMI. Waist size is an easy method to gauge health risk, and its maintenance through lifestyle changes might be the key to cancer prevention.
Track Your Waist Size: Regularly measure your waist circumference and try to keep it in a healthy range (below 40 inches for men, according to medical advice).
Eat a Balanced Diet: A diet containing high fiber, lean protein, and healthy fats can assist in limiting visceral fat gain.
Exercise Consistently: Regular exercise with a combination of aerobic and strength training will help maintain a healthy waistline.
Control Stress and Sleep: Persistent stress and inadequate sleep tend to cause weight gain, especially in the midsection of the body.
Regular Health Screenings: Early identification of cancer risk factors through regular screening can greatly enhance long-term health status.
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Fasting for three hours before bed can significantly improve heart health and reduce the risk of coronary artery disease (CAD) as well as other chronic conditions, an Arteriosclerosis, Thrombosis, and Vascular Biology study suggests.
While many believe that diet plans such as intermittent fasting or time-restricted eating can help reduce their weight, researchers at Northwestern University have found that not eating three hours before going to sleep can reduce overnight blood pressure by nearly four percent, heart rate by five percent and strengthen overall heart rhythms.
This can help reduce overall strain on the heart which lowers risks for conditions like hypertension and CAD. Additionally, the scientists also discovered a drop in blood sugar levels, improved glucose tolerance and insulin sensitivity.
Participants who underwent glucose tests also showed better insulin release which tend to stabilize during the day. Additionally, an improved heart rate also lowered nighttime cortisol, which helped in metabolic balance.
Dr. Phyllis Zee, director of the Center for Circadian and Sleep Medicine and chief of sleep medicine in the department of neurology at Feinberg and corresponding author said of the results: "It's not only how much and what you eat, but also when you eat relative to sleep that is important for the physiological benefits of time-restricted eating."
The study authors also noted: "Extending overnight fasting duration by three hours in alignment with sleep improved cardiometabolic health in middle-aged/older adults by strengthening coordination between circadian- and sleep-regulated autonomic and metabolic activity.
"This sleep-aligned time-restricted eating approach represents a novel, accessible lifestyle intervention with promising potential for improving cardiometabolic function."
Despite being as a common heart disease, coronary artery disease (CAD) develops over years and has no clear signs and symptoms apart from a heart attack. The illness begins due to a buildup of fats, cholesterol and other substances known as plaque in and on the artery walls.
Over time, this can cause narrowing or blockage of the coronary arteries and block the supply of oxygen-rich blood to heart which can lead chest pain (angina), shortness of breath and ultimately, heart attacks.
Typically, those above the age of 45, having a biological family member with heart disease, lack of sleep, smoking, consuming saturated fats along with other autoimmune diseases such as lupus and rheumatoid arthritis can increase the risk of developing CAD.
Treatment options may include medicines and surgery. Eating a nutritious diet, getting regular exercise and not smoking can help also prevent CAD and the conditions that can cause it.
Nearly one in 10 Indian adults suffer from CAD and about two million people die from the disease annually. Apart from this, about 18 to 20 million American adults aged 20 and older are also affected about the disease.
One in seven stroke patients in India are young adults aged below 45 years, with hypertension leading as the major risk factor, according to a study by the Indian Council of Medical Research (ICMR).
The Global Burden of Disease Study 2021 identified hypertension, air pollution, tobacco smoking, high cholesterol, increased salt intake, and diabetes as the leading risk factors of stroke.
Incidence of stroke is increasing significantly in low- and middle-income countries (LMICs), especially in India, due to population growth, aging, and greater exposure to risk factors.
Quitting smoking is one of the most important steps a person can take to improve their health. But research suggests that women face unique challenges that make it harder to stop smoking and remain nicotine-free as compared with men.
According to the Centers for Disease Control and Prevention, about 10 percent of women in the US currently smoke cigarettes. Each year, while many attempt to quit, maintaining long term abstinence remains difficult for a large number of smokers.
Scientists say these differences are not about motivation and women are usually just as willing to quit smoking as men. In many cases they are even more likely to seek help through smoking cessation programs, counseling or medical treatment.
However, the challenge lies in a combination of biological, psychological and social factors that can make nicotine addiction behave differently in women.
One of the biggest reasons for the difference is biological as women process nicotine differently than men.
Research shows that women tend to metabolize nicotine faster. This means nicotine leaves the body more quickly, which can lead to stronger withdrawal symptoms and more frequent cravings. Jean Perriot, MD, an addiction specialist at the Émile Roux Dispensary in France, says this biological difference can affect treatment.
Even though doctors sometimes worry about giving women too much nicotine replacement therapy, such as patches or gum, biological measurements often show that many women actually receive too little nicotine replacement, which can make treatment less effective.
Hormones also play a role in smoking behavior. Studies suggest that cravings may increase when estrogen levels are high and decrease when progesterone levels rise. These hormonal shifts occur naturally during the menstrual cycle and may influence when quitting attempts are most successful.
Dr Nancy Rigotti, director of the Tobacco Research and Treatment Center at Massachusetts General Hospital who specializes in smoking cessation for many years notes that emotional triggers such as stress or depression can strongly influence smoking behavior among women.
Social and economic pressures may also increase vulnerability to tobacco use. Historically, the tobacco industry has targeted women with marketing campaigns that connect smoking with weight control, independence or attractiveness. Public health experts say these messages can shape attitudes about smoking and reinforce addictive behaviors.
Behavioral research suggests these cues may have a stronger influence for some women, which can make quitting harder even when nicotine dependence is treated.
Furthermore, nicotine can suppress appetite, leading may to pick up smoking to manage body weight. Studies show that women are more likely than men to experience increased cravings for high sugar or high fat foods after quitting smoking. They also tend to gain slightly more weight on average which can make some women hesitant to quit or more likely to relapse.
Research suggests nicotine replacement therapy may need to be carefully adjusted because of faster nicotine metabolism in women. Some medications used to help people quit smoking may also have different effects.
For example, studies suggest the medication varenicline may cause more side effects in women, while the drug bupropion may be somewhat less effective for female smokers.
On the other hand, behavioral treatments appear to work well for many women. Cognitive behavioral therapy, which helps people understand and change unhealthy habits, may be slightly more effective for women than men. Women are also more likely to try complementary approaches such as meditation, yoga or hypnosis when attempting to quit smoking.
Exposure to secondhand smoke is another concern. Studies show women are often more likely to be exposed to tobacco smoke at home or in shared environments. Some research also suggests women may face higher risks of certain tobacco related diseases even at lower levels of smoking.
Understanding these differences can help doctors design better quitting strategies. Scientists say the goal is not simply to encourage people to quit smoking, but to provide the right tools so that quitting becomes more achievable for everyone.
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Often called the stress hormone, cortisol is produced by your adrenal glands, located on top of the kidneys. The hormone plays a critical role in keeping you healthy and maintaining your energy as well cardiovascular health.
Cortisol is a necessary tool for survival and naturally peaks in the morning to help you wake up and drop at night to help you sleep. While the body has a system in place to maintain hormone levels, issues arise when cortisol levels stay chronically high, meaning your body is constantly in "fight-or-flight" mode.
This can happen due to long-term stress, certain medical conditions (like Cushing’s Syndrome), or the prolonged use of steroid medications.
However, Dr Suman Agrawal, a renowned Oxford University certified nutritionist and qualified fitness expert has shared how "Shin-Kokyu”, a technique used by Japanese samurais before a battle exercise can help reduce cortisol by 80 percent
Step One: Box breathing method:
Place three fingers below the navel with medium force & hold throughout the breathing. There’s a cluster of vagus nerve endings there. It’s like a button in the body.
Step Three: Gaze into nowhere
Look straight ahead and defocus your gaze as if you are looking through a wall for three minutes. This time span is equal to 12 breathing cycles which is the minimum time needed to reboot the nervous system.
If high cortisol levels are left un-addressed for an extended period, they can lead to serious health complications, including:
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