When was the last time you measured your waistline? If you assume that BMI is the only number to focus on when it comes to your health, think twice. New research has revealed a shocking revelation—your waist circumference might be a far better predictor of men's cancer risk than BMI.

The study finds that for each 4-inch increase in waist size, a man's risk of cancer increases by a staggering 25%. Meanwhile, BMI, commonly regarded as the gold standard for assessing obesity, raises cancer risk by only 19% for the same weight gain. So, if you've been dismissing that pesky belly fat, it's time to take notice.

But why is your waistline so important? The reason is visceral fat—the hidden, deep fat that accumulates around your organs. Unlike other body fat, visceral fat is a stealthy troublemaker, causing inflammation, insulin resistance, and abnormal blood fat levels—all of which combine to create a cancer-perfect storm.

Obesity has been associated with an increased risk of numerous health conditions, including cancer, for decades. The research, though, indicates that a specific measure of the body—waist circumference—may be an even more reliable forecaster of cancer risk in men than the more frequently employed Body Mass Index (BMI). This finding emphasizes the need to pay particular attention to the distribution of fat and not merely to the weight of the body.

BMI has been the go-to measure for years for gauging health risks related to obesity. New research, though, that appears in The Journal of the National Cancer Institute indicates that waist measurement is a better predictor of cancer risk in men. According to the research, four more inches (10 cm) around the waist will add 25% to a man's cancer risk. Conversely, a 3.7 kg/m² rise in BMI (from a BMI of 24 to 27.7) increased cancer risk by only 19%.

Why is waist circumference a better predictor, then? Unlike BMI, which measures weight relative to height, waist circumference actually measures abdominal fat—specifically, visceral fat. This type of fat encircles internal organs and is also linked to higher levels of inflammation, insulin resistance, and abnormal blood lipids, all of which are factors in cancer growth. BMI, however, does not measure fat distribution, so two individuals with the same BMI can have very different levels of health risk depending on where fat is deposited on their bodies.

Why Men Are at Higher Risk?

Interestingly, the research identified a significant difference between men and women when it came to waist circumference and cancer risk. Although waist circumference and BMI were linked with obesity-related cancers in women, the relationship was weaker than for men. An increase of 12 cm (4.7 inches) in waist size or a 4.3 rise in BMI (from 24 to 28.3) raised the cancer risk in women by just 13%—a much lower percentage than for men.

Experts credit this difference to the way that fat is stored in the body. Men are more likely to carry fat around the abdomen, especially as visceral fat, which is more metabolically active and associated with cancer-producing biological alterations. Women, by contrast, store fat in peripheral sites such as the hips and thighs, where it is less likely to drive systemic inflammation and metabolic disturbances.

A possible reason is that men tend to depot fat more in the visceral regions, whereas women tend to carry more subcutaneous and peripheral fat," wrote the researchers. "This may render waist circumference a more robust risk factor for cancer in men and account for why waist circumference provides additional risk information beyond BMI in men but not women."

Cancer Types Most Linked to Abdominal Fat

The research used the International Agency for Research on Cancer (IARC) data to define obesity-related cancers. These cancers are esophageal (adenocarcinoma), gastric (cardia), colorectal, rectal, liver, gallbladder, pancreatic, renal, and thyroid cancers, and multiple myeloma and meningioma. In men, abdominal obesity is especially significant in raising the risk of these cancers through high levels of insulin and markers of inflammation.

For women, the research proposes that both waist circumference and hip circumference may give a more accurate estimate of visceral fat and cancer risk. "Adding hip circumference to risk models could strengthen the link between waist circumference and cancer, especially in women," researchers observed.

What This Means for Men's Health and Cancer Prevention?

With these results, doctors advise men to be more mindful of their waistline than only their BMI. Waist size is an easy method to gauge health risk, and its maintenance through lifestyle changes might be the key to cancer prevention.

How To Reduce Cancer Risk In Men?

Track Your Waist Size: Regularly measure your waist circumference and try to keep it in a healthy range (below 40 inches for men, according to medical advice).

Eat a Balanced Diet: A diet containing high fiber, lean protein, and healthy fats can assist in limiting visceral fat gain.

Exercise Consistently: Regular exercise with a combination of aerobic and strength training will help maintain a healthy waistline.

Control Stress and Sleep: Persistent stress and inadequate sleep tend to cause weight gain, especially in the midsection of the body.

Regular Health Screenings: Early identification of cancer risk factors through regular screening can greatly enhance long-term health status.

While salt is often blamed for high blood pressure, it is not the only factor contributing to those numbers. Many people carefully reduce salt intake yet continue to struggle with hypertension because several hidden causes often go unnoticed.

Understanding these triggers can help people take better control of their heart health before complications arise.

One major but overlooked reason is chronic stress. When the body stays under constant mental pressure, stress hormones like cortisol and adrenaline rise repeatedly. This causes blood vessels to tighten and the heart to work harder, gradually increasing blood pressure over time. Poor sleep also plays a significant role. People who sleep less than six hours regularly or suffer from conditions like sleep apnea may experience uncontrolled hypertension despite following a healthy diet.

Hormonal imbalance is another hidden culprit. Disorders of the thyroid or adrenal glands, as well as conditions like PCOS, can affect blood pressure regulation. In some individuals, high blood pressure may actually begin because of hormonal changes rather than lifestyle alone. This is why persistent hypertension should never be ignored or treated casually at home.

Certain medications can also cause a silent increase in blood pressure. Frequent use of painkillers, steroids, nasal decongestants, birth control pills, or even some herbal supplements may contribute to rising readings. Excessive caffeine, smoking, alcohol consumption, and a sedentary lifestyle further add to the risk.

Weight gain around the abdomen is particularly harmful because it increases resistance in blood vessels and affects how the body handles insulin. Similarly, unmanaged diabetes and high cholesterol damage arteries over time, making it harder for blood to flow normally.

Another commonly missed factor is dehydration. When the body lacks enough water, sodium concentration rises, forcing the heart to pump harder. Even low potassium intake from poor dietary habits can disturb the body’s blood pressure balance.

Why Regular Monitoring Is Important

High blood pressure is often called a “silent killer” because symptoms may not appear until serious complications develop.

Regular health check-ups, monitoring blood pressure at home, staying physically active, sleeping well, and identifying underlying medical conditions are equally important as reducing salt intake.

Managing hypertension requires looking at the complete picture, not just the salt shaker on the dining table.

In India, more than one in four people has hypertension, and cumulatively, over 90 per cent of adults with hypertension are either undiagnosed, untreated, or treated but still live with uncontrolled blood pressure. Experts say this growing burden needs urgent attention.

In an interview with HealthandMe on World Hypertension Day 2026, Professor Vivekanand Jha, Executive Director of The George Institute for Global Health, suggested that one practical solution may be as simple as switching to potassium-enriched low-sodium salt substitutes (LSSS).

Current estimates show that Indians consume between 8 and 11 grams of salt (equivalent to 3.2–4.4 grams of sodium) per day — nearly double the World Health Organization recommended limit of 5 grams of salt (2 grams of sodium).

Low-sodium salt substitutes are composed of approximately 70–75 per cent sodium chloride and 25–30 per cent potassium chloride. They reduce sodium intake while increasing potassium consumption, helping lower blood pressure and reduce cardiovascular risk.

In January 2025, the World Health Organization released guidelines recommending potassium-enriched salt substitutes to combat hypertension and related heart risks. The guidelines suggest replacing regular table salt, which is high in sodium, with potassium-enriched alternatives that may help reduce noncommunicable diseases such as cardiovascular disease and chronic kidney disease by lowering blood pressure.

Dr Jha was also part of a consensus statement released by experts in clinical medicine, public health, and nutrition, recommending potassium-enriched low-sodium salt substitutes as an effective intervention to reduce hypertension and cardiovascular disease in India.

Here are excerpts from the interview:

Q. Is asking people to simply switch to a healthier salt more realistic than expecting them to completely change their diets?

Dr Jha: Public health works best when solutions fit naturally into people’s daily lives. Asking families to completely change what they eat is extremely difficult because food habits are emotional, cultural, and built over generations. But asking them to switch the type of salt they use at home is a much simpler and more achievable step. The taste remains familiar, cooking habits do not change, and yet the health benefits can begin immediately.

In a country like India, where a large proportion of sodium intake comes from salt added during cooking, this becomes a very practical intervention. It is not about perfection — it is about finding solutions that ordinary families can realistically adopt and sustain. There are, of course, other dietary factors that also need attention, such as excessive sugar intake, processed foods, and poor fruit consumption.

Q. High blood pressure medicines are often prescribed quickly. Are doctors giving enough importance to simple dietary changes like switching to healthier salt, or is prevention still underestimated?

Dr Jha: The answer is a definite no.

Our healthcare system is designed around managing disease once it appears, rather than reducing people’s need to come to hospitals by preventing disease in the first place.

Also read: Can Hantavirus Spread Through Semen And Breast Milk? What Experts Say

In a busy clinic, physicians often have only a few minutes with each patient, making detailed dietary counselling difficult. At the same time, advice like “eat less salt” can feel abstract or impractical for many patients. There are also systemic incentives that prioritize medicines over preventive care.

We need much stronger integration of nutrition and prevention into routine medical practice. If we truly want to reduce the burden of hypertension and its complications — including cardiovascular disease, stroke, and chronic kidney disease — prevention cannot remain an afterthought.

Q. Low-sodium salt may not suit some people with kidney disease or those on certain medicines. How can these risks be managed without discouraging the wider population from benefiting?

Dr Jha: This is an important conversation and needs to be handled responsibly and transparently. There is a small group of patients — particularly some people with advanced kidney disease or those on specific medications — for whom excess potassium may not be appropriate.

However, for the vast majority of the population, including many people with early-stage kidney disease, low-sodium salt substitutes are safe and beneficial. We have repeatedly shown this through modelling studies.

The challenge is ensuring that a legitimate caution for one group does not unintentionally discourage everyone else. That is why clear labelling, better awareness among healthcare professionals, and honest public communication are essential. Public health decisions are often about balancing risks and benefits, and in this case, the potential population-level benefits are very significant, including for a large majority of patients with chronic kidney disease.

Read More: Heart Diseases, Mental Disorders And Cancer Among 62 Health Risks Linked To Alcohol Use: Study

Q. Emerging evidence suggests increasing potassium may be as important as reducing sodium. Does this change how India should approach hypertension prevention?

Dr Jha: This is a very important point and broadens the conversation in a meaningful way. As it turns out, many physicians are also unaware that potassium intake among Indians is substantially lower than recommended, and that increasing potassium intake can help lower blood pressure and improve cardiovascular health.

What makes low-sodium salt substitutes particularly valuable is that they address both issues together — they reduce sodium while increasing potassium through a product people already use every day. This dual benefit could make a meaningful difference at scale.

It does not replace the need for healthier diets overall, but it does provide a practical and scalable public health tool.

Climate change and rapid urbanization are changing mosquito habitats, and shifting dengue serotypes are reshaping the disease landscape in India. As a result, the country is now witnessing a transformation in how dengue spreads, who it affects, and how severe infections can become.

Once considered a seasonal monsoon illness, dengue is now increasingly becoming a year-round public health challenge, extending into hill states, semi-urban regions, and previously low-risk geographies.

In an exclusive interview with HealthandMe, Dr. Shikha Taneja Malik, Senior Scientific Affairs Manager, Drugs for Neglected Diseases initiative (DNDi), South Asia, discussed why India’s dengue numbers are likely being massively undercounted, how surveillance and diagnostic gaps are masking the real scale of the crisis, and why young adults are facing more severe infections due to changing serotypes.

Dr. Shikha also explained the urgent global push for affordable therapeutics and the challenges India still faces in developing an indigenous dengue vaccine despite its strong manufacturing capacity.

Here are the excerpts from the interview:

Q. Dengue was always called a monsoon disease. Is that label now dangerously misleading?

Dr. Shikha: Yes, I would argue that labels are not just outdated but risky, too. What we are seeing across India and across the region is a fundamental shift in the transmission pattern.

Dengue used to follow a fairly predictable seasonal curve — cases would spike between July and November, track the monsoon, and then recede. That curve is flattening. We are now seeing cases in February, March, and May — months that were previously considered safe. Delhi, Mumbai, Bengaluru — cities that used to have clear off-seasons for dengue — are reporting year-round transmission.

Warmer temperatures, altered rainfall patterns, unplanned urbanization, and poor sanitation have lengthened transmission seasons, making dengue a year-round systemic crisis. Models now predict year-round transmission in coastal regions, though monsoon months will retain the highest peak.

Also read: National Dengue Day 2026: India Reports 6,927 Cases And 10 Deaths In 2026

Q. Are serotype shifts driving changing dengue patterns, especially in young adults?

Dr. Shikha: Yes, India is witnessing active serotype shifts, and they directly explain rising severity, especially in young adults. Initial infection with one of the four dengue serotypes results in lifelong immunity to that specific serotype. Whereas, a secondary infection with a different serotype can trigger Antibody-Dependent Enhancement (ADE).

Young adults who were exposed to one serotype in childhood are now encountering a new dominant serotype, making them especially vulnerable to severe secondary infections.

Q. Is India undercounting dengue cases? Why do so many cases go unreported?

Dr. Shikha: The 2.89 lakh figure in 2023 is what our surveillance system captures, but it is almost certainly a fraction of the true burden. The Lancet has estimated that India accounts for around 33 per cent of the global dengue burden, and globally, we are looking at approximately 400 million infections every year. That puts India's real annual dengue burden potentially in the tens of millions — not hundreds of thousands.

Few studies have shown that the estimates of actual cases are approximately 282 times higher.

There are several reasons why cases go unreported, and they compound each other.

• A large proportion of infections are either asymptomatic or present as a generic fever — patients never seek formal care.
• Our surveillance system is passive and fragmented. Reporting is largely dependent on public health facilities.
• Confirmatory testing through NS1 antigen tests or PCR requires infrastructure that is not yet uniformly available at the primary health center level, particularly in rural and semi-urban areas.

Q. Are previously dengue-free regions in India now reporting cases due to climate change?

Dr. Shikha: Yes, the geographic spread is both significant and well-documented. Climate change is playing a major role in this shift. Rising temperatures, changing rainfall patterns, increasing humidity, and rapid unplanned urbanization are creating more favorable conditions for Aedes aegypti mosquitoes to survive and transmit the virus for longer periods each year.

Since the mid-1990s, dengue has rapidly spread to regions where it was historically non-existent, including Odisha, Arunachal Pradesh, and Mizoram. In the early 2000s, dengue was endemic only in a few southern and northern states; it has since spread to many states, including union territories.

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The shift is particularly visible in hilly and cooler geographies such as Himachal Pradesh and Jammu & Kashmir. Climate modelling projects further expansion of Aedes albopictus into upper Himalayan regions, including Leh-Ladakh and Arunachal Pradesh, by 2050.

Q. What are the biggest challenges in indigenous dengue vaccine production in India?

Dr. Shikha: India has strong vaccine manufacturing capacity, but dengue remains scientifically complex. Existing vaccines have limitations and do not cover all vulnerable groups.

India’s first Phase 3 trial for an indigenous dengue vaccine, DengiAll, is underway across 18 states. The Butantan vaccine candidate, originally developed by NIH, has been licensed to Indian companies, including Panacea, SIIPL, and Indian Immunologicals, with the ICMR-Panacea candidate being the most advanced.

The recent DCGI approval of Qdenga is encouraging, but sustained financing and coordination between ICMR, DBT, and industry will be critical for developing a truly indigenous vaccine.