When was the last time you measured your waistline? If you assume that BMI is the only number to focus on when it comes to your health, think twice. New research has revealed a shocking revelation—your waist circumference might be a far better predictor of men's cancer risk than BMI.

The study finds that for each 4-inch increase in waist size, a man's risk of cancer increases by a staggering 25%. Meanwhile, BMI, commonly regarded as the gold standard for assessing obesity, raises cancer risk by only 19% for the same weight gain. So, if you've been dismissing that pesky belly fat, it's time to take notice.

But why is your waistline so important? The reason is visceral fat—the hidden, deep fat that accumulates around your organs. Unlike other body fat, visceral fat is a stealthy troublemaker, causing inflammation, insulin resistance, and abnormal blood fat levels—all of which combine to create a cancer-perfect storm.

Obesity has been associated with an increased risk of numerous health conditions, including cancer, for decades. The research, though, indicates that a specific measure of the body—waist circumference—may be an even more reliable forecaster of cancer risk in men than the more frequently employed Body Mass Index (BMI). This finding emphasizes the need to pay particular attention to the distribution of fat and not merely to the weight of the body.

BMI has been the go-to measure for years for gauging health risks related to obesity. New research, though, that appears in The Journal of the National Cancer Institute indicates that waist measurement is a better predictor of cancer risk in men. According to the research, four more inches (10 cm) around the waist will add 25% to a man's cancer risk. Conversely, a 3.7 kg/m² rise in BMI (from a BMI of 24 to 27.7) increased cancer risk by only 19%.

Why is waist circumference a better predictor, then? Unlike BMI, which measures weight relative to height, waist circumference actually measures abdominal fat—specifically, visceral fat. This type of fat encircles internal organs and is also linked to higher levels of inflammation, insulin resistance, and abnormal blood lipids, all of which are factors in cancer growth. BMI, however, does not measure fat distribution, so two individuals with the same BMI can have very different levels of health risk depending on where fat is deposited on their bodies.

Why Men Are at Higher Risk?

Interestingly, the research identified a significant difference between men and women when it came to waist circumference and cancer risk. Although waist circumference and BMI were linked with obesity-related cancers in women, the relationship was weaker than for men. An increase of 12 cm (4.7 inches) in waist size or a 4.3 rise in BMI (from 24 to 28.3) raised the cancer risk in women by just 13%—a much lower percentage than for men.

Experts credit this difference to the way that fat is stored in the body. Men are more likely to carry fat around the abdomen, especially as visceral fat, which is more metabolically active and associated with cancer-producing biological alterations. Women, by contrast, store fat in peripheral sites such as the hips and thighs, where it is less likely to drive systemic inflammation and metabolic disturbances.

A possible reason is that men tend to depot fat more in the visceral regions, whereas women tend to carry more subcutaneous and peripheral fat," wrote the researchers. "This may render waist circumference a more robust risk factor for cancer in men and account for why waist circumference provides additional risk information beyond BMI in men but not women."

Cancer Types Most Linked to Abdominal Fat

The research used the International Agency for Research on Cancer (IARC) data to define obesity-related cancers. These cancers are esophageal (adenocarcinoma), gastric (cardia), colorectal, rectal, liver, gallbladder, pancreatic, renal, and thyroid cancers, and multiple myeloma and meningioma. In men, abdominal obesity is especially significant in raising the risk of these cancers through high levels of insulin and markers of inflammation.

For women, the research proposes that both waist circumference and hip circumference may give a more accurate estimate of visceral fat and cancer risk. "Adding hip circumference to risk models could strengthen the link between waist circumference and cancer, especially in women," researchers observed.

What This Means for Men's Health and Cancer Prevention?

With these results, doctors advise men to be more mindful of their waistline than only their BMI. Waist size is an easy method to gauge health risk, and its maintenance through lifestyle changes might be the key to cancer prevention.

How To Reduce Cancer Risk In Men?

Track Your Waist Size: Regularly measure your waist circumference and try to keep it in a healthy range (below 40 inches for men, according to medical advice).

Eat a Balanced Diet: A diet containing high fiber, lean protein, and healthy fats can assist in limiting visceral fat gain.

Exercise Consistently: Regular exercise with a combination of aerobic and strength training will help maintain a healthy waistline.

Control Stress and Sleep: Persistent stress and inadequate sleep tend to cause weight gain, especially in the midsection of the body.

Regular Health Screenings: Early identification of cancer risk factors through regular screening can greatly enhance long-term health status.

Winters can be especially demanding for many women going through menopause or perimenopause. As the colder months arrive, concerns like dry, irritated skin, unexpected hair fall, and increased joint pain become more common. This rise in symptoms is not caused by cold weather alone. It is largely driven by the way seasonal changes interact with the hormonal transitions of menopause. To understand this better, we spoke to Tamanna Singh, Co-founder of Menoveda and a Certified Menopause Coach, who explained why these changes happen.

What Is Menopause?

Menopause is a natural biological phase when a woman’s menstrual cycles stop permanently, signalling the end of her reproductive years. It is officially diagnosed after 12 consecutive months without a period and usually occurs between the ages of 45 and 55, as the ovaries gradually reduce estrogen production.

The phase leading up to this, called perimenopause, involves fluctuating hormones that can trigger symptoms such as hot flashes, mood changes, and sleep disturbances. Postmenopause refers to the stage after menopause, according to the Mayo Clinic.

How Long Does Menopause Last?

Menopause itself is a single milestone rather than a prolonged phase. Once a woman has gone a full year without a menstrual period, she is considered menopausal. After this point, she enters postmenopause, which continues for the rest of her life.

Menopausal Symptoms Worsening During Winters

One of the key changes during menopause is the steady decline in estrogen levels. Estrogen supports skin moisture, collagen formation, healthy hair growth cycles, and joint lubrication. As this hormone decreases, the body becomes more reactive to environmental factors, with winter dryness having a stronger impact.

Menopause In Winters: Why Skin Feels Drier in January

Tamanna Singh explains, “Cold air contains less moisture, and indoor heating further removes the skin’s natural oils. Lower estrogen levels weaken the skin’s protective barrier, increasing water loss. This leads to dryness, flaking, itching, and in some cases, eczema-like conditions. The skin also takes longer to repair itself, which makes winter-related irritation more difficult to manage.”

The Hair Fall Connection

Hair follicles respond closely to hormonal changes. Tamanna notes, “During menopause, shifting estrogen levels and increased androgen activity shorten the hair’s growth phase, leading to more shedding. Winter adds further stress through reduced blood flow to the scalp, dietary imbalances after festive eating, and low Vitamin D levels due to limited sunlight. Combined, these factors make January a common time for noticeable hair thinning and hair fall.”

Why Joint Pain Worsens During Menopause?

Estrogen also plays a role in reducing inflammation and keeping joints well-lubricated. As estrogen levels fall, women may experience stiffness, swelling, and discomfort, which tend to worsen in cold weather. Lower temperatures cause muscles and connective tissues to tighten, reducing flexibility. Staying less active during winter months further adds to joint stiffness and pain.

What Can Help?

Managing these concerns calls for a well-rounded approach. Tamanna recommends:

• Skin: Use rich, oil-based moisturisers regularly and maintain good hydration.
• Hair: Ensure sufficient intake of protein, iron, and biotin, and practice gentle scalp massage to improve blood circulation.
• Joints: Engage in light strength training, yoga, and regular movement to support flexibility. Adequate Vitamin D and calcium intake is especially important during winter.

Winter does not create menopausal symptoms. It simply intensifies what the body is already dealing with. With the right awareness, consistent care, and small seasonal adjustments, women can navigate the colder months with more ease and confidence.

Delhi’s air quality remained in ‘very poor’ category and a thick layer of fog also took over the city. As of 6am, the Air Quality Index or AQI stood at 385. On Monday, the AQI of the city stayed under the ‘severe’ category, and the overall 24-hour average was at 401. The India Meteorological Department (IMD) recorded that the general visibility of Delhi at 6.30am was 350 meters. The IMD also issued a fog alert for December 29 and the morning of December 30. Warning is also extended for neighboring states, including Haryana, Uttar Pradesh, Chandigarh, Punjab, and parts of Northeast, East, and North India.

The IMD on X wrote: “Dense to very dense fog is expected tonight and into the morning of 30th December across several regions including Haryana, Chandigarh & Delhi, Punjab, Uttar Pradesh, and parts of the Northeast, East, and North India. Visibility may be severely reduced, making travel risky. Please drive slowly, use fog lights, and avoid unnecessary journeys.”

Also Read: Is Delhi's Toxic Air Making You Sad And Grumpy? Here's What The Study Says

Pollution Could Harm Your Brain

While we all know the harm pollution could do to your lungs, doctors have also highlighted that pollution could also lead to cognitive ailments. Mental health impacts such as risk of depression, anxiety, ADHD, and neurodevelopmental disorders in children could rise.

Dr Deepika Dahima, a psychologist at AIIMS Delhi said that pollution could put mental health at risk. Prolonged exposure to fine particulate matter like PM10 or PM2.5 could lead to a rise in anxiety, depression, cognitive impairment and chronic stress. Children also show disrupted neural development and learning difficulties, while adults experience irritability, emotional fatigue and impaired decision-making.

Another medical practitioner, Dr Jitender Nagpal, deputy medical superintendent and pediatrician at Sitaram Bhartia Institute of Science, speaking to the news agency PTI said, “Increasingly, a wide spectrum of behavioural and learning issues such as attention difficulties, irritability, and poor academic performance are being noticed in many children.”

Studies too have linked the exposure of particulate matter or PM2.5 with increased ADHD risk. There are research that show a 1.51 fold increase per 5 μg/m³ increase in PM2.5 and others indicating elevated risks when exposure exceeds 16 μg/m³.

Another study published in December 18, in the journal Environmental Research by Oregon Health & Science University, found that everyday exposure to urban air pollution gradually alters brain development in children and young adults. The researchers of the Oregon Health & Science University discovered that exposure to air pollutants at ages 9 to 10 was associated with changes in cortical thickness in the frontal and temporal brain regions that are responsible for executive function, language, mood regulation, and socioemotional processing.

Another study published in Nature Communication notes that after four hours of exposure to particulate matter, it was found that people's ability to perform routine tasks and interpret emotions were highly impacted.

Study's co-author, Dr Thomas Faherty said, "Study provides compelling evidence that even short-term exposure to particulate matter can have immediate negative effects on brain functions essential for daily activities.”

Can Alzheimer's be completely reversed? This is not just about preventing it or ensuring it that the disease slow down, but can it be reversed to achieve full neurological recovery? For the longest, we have known that Alzheimer's is a progressive, degenerative brain disease, which destroys memory, thinking, and eventually the ability to perform simple tasks, but now a team of researchers from Case Western Reserve University, University Hospitals (UH), and Louis Stokes Cleveland VA Medical Center has challenged this belief. They may have found out something that could reverse it, at least so says the animal model.

Instead of targeting plaques or tangles alone, the team looked at something more fundamental: the brain’s energy system.

Their findings, published in Cell Reports Medicine, suggest that restoring the brain’s energy balance may not just slow Alzheimer’s but potentially reverse key features of the disease, at least in animal models.

What Did The Study Find?

The study is led by Kalyani Chaubey from the Pieper Laboratory, and at the center of the study is NAD+, a molecule essential for cellular energy and repair.

NAD+ levels naturally decline with age across the body, including in the brain. When levels drop too low, cells struggle to perform basic functions and eventually fail.

The researchers found that this decline is far more severe in the brains of people with Alzheimer’s. The same sharp drop was also seen in mouse models of the disease, pointing to a shared biological problem.

How the study was conducted

While Alzheimer’s is uniquely human, scientists use specially engineered mice to study it. In this study, two types of mice were used. One model carried human mutations linked to amyloid buildup, while the other carried a mutation affecting the tau protein.

Both amyloid and tau are central to Alzheimer’s pathology. Over time, these mice developed symptoms similar to human Alzheimer’s, including brain inflammation, damage to nerve fibers, breakdown of the blood-brain barrier, reduced formation of new neurons, and severe memory and learning problems.

Restoring energy balance in diseased brains

After confirming that NAD+ levels were dramatically reduced, the researchers tested whether restoring this balance could help. They used a drug called P7C3-A20, developed in the Pieper Laboratory, which supports cells in maintaining healthy NAD+ levels under stress.

Remarkably, the results went beyond prevention. Even when treatment began after significant disease progression, the mice showed reversal of major brain damage. Cognitive function fully recovered in both mouse models, despite their different genetic causes.

Biomarkers and what they signal

The recovery was not just behavioral. Blood levels of phosphorylated tau 217, a biomarker now used clinically in humans to detect Alzheimer’s, returned to normal in treated mice. This provided objective evidence that disease processes had been reversed, not merely masked.

Why this matters for people

The findings suggest a possible paradigm shift. Alzheimer’s damage may not always be permanent. Under certain conditions, the brain appears capable of repairing itself and regaining function.

However, the researchers caution against self-medicating with over-the-counter NAD+ supplements. Some have been shown in animal studies to raise NAD+ to unsafe levels that may increase cancer risk. The drug used in this study works differently, supporting balance rather than excess.