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When was the last time you measured your waistline? If you assume that BMI is the only number to focus on when it comes to your health, think twice. New research has revealed a shocking revelation—your waist circumference might be a far better predictor of men's cancer risk than BMI.
The study finds that for each 4-inch increase in waist size, a man's risk of cancer increases by a staggering 25%. Meanwhile, BMI, commonly regarded as the gold standard for assessing obesity, raises cancer risk by only 19% for the same weight gain. So, if you've been dismissing that pesky belly fat, it's time to take notice.
But why is your waistline so important? The reason is visceral fat—the hidden, deep fat that accumulates around your organs. Unlike other body fat, visceral fat is a stealthy troublemaker, causing inflammation, insulin resistance, and abnormal blood fat levels—all of which combine to create a cancer-perfect storm.
Obesity has been associated with an increased risk of numerous health conditions, including cancer, for decades. The research, though, indicates that a specific measure of the body—waist circumference—may be an even more reliable forecaster of cancer risk in men than the more frequently employed Body Mass Index (BMI). This finding emphasizes the need to pay particular attention to the distribution of fat and not merely to the weight of the body.
BMI has been the go-to measure for years for gauging health risks related to obesity. New research, though, that appears in The Journal of the National Cancer Institute indicates that waist measurement is a better predictor of cancer risk in men. According to the research, four more inches (10 cm) around the waist will add 25% to a man's cancer risk. Conversely, a 3.7 kg/m² rise in BMI (from a BMI of 24 to 27.7) increased cancer risk by only 19%.
Why is waist circumference a better predictor, then? Unlike BMI, which measures weight relative to height, waist circumference actually measures abdominal fat—specifically, visceral fat. This type of fat encircles internal organs and is also linked to higher levels of inflammation, insulin resistance, and abnormal blood lipids, all of which are factors in cancer growth. BMI, however, does not measure fat distribution, so two individuals with the same BMI can have very different levels of health risk depending on where fat is deposited on their bodies.
Interestingly, the research identified a significant difference between men and women when it came to waist circumference and cancer risk. Although waist circumference and BMI were linked with obesity-related cancers in women, the relationship was weaker than for men. An increase of 12 cm (4.7 inches) in waist size or a 4.3 rise in BMI (from 24 to 28.3) raised the cancer risk in women by just 13%—a much lower percentage than for men.
Experts credit this difference to the way that fat is stored in the body. Men are more likely to carry fat around the abdomen, especially as visceral fat, which is more metabolically active and associated with cancer-producing biological alterations. Women, by contrast, store fat in peripheral sites such as the hips and thighs, where it is less likely to drive systemic inflammation and metabolic disturbances.
A possible reason is that men tend to depot fat more in the visceral regions, whereas women tend to carry more subcutaneous and peripheral fat," wrote the researchers. "This may render waist circumference a more robust risk factor for cancer in men and account for why waist circumference provides additional risk information beyond BMI in men but not women."
The research used the International Agency for Research on Cancer (IARC) data to define obesity-related cancers. These cancers are esophageal (adenocarcinoma), gastric (cardia), colorectal, rectal, liver, gallbladder, pancreatic, renal, and thyroid cancers, and multiple myeloma and meningioma. In men, abdominal obesity is especially significant in raising the risk of these cancers through high levels of insulin and markers of inflammation.
For women, the research proposes that both waist circumference and hip circumference may give a more accurate estimate of visceral fat and cancer risk. "Adding hip circumference to risk models could strengthen the link between waist circumference and cancer, especially in women," researchers observed.
With these results, doctors advise men to be more mindful of their waistline than only their BMI. Waist size is an easy method to gauge health risk, and its maintenance through lifestyle changes might be the key to cancer prevention.
Track Your Waist Size: Regularly measure your waist circumference and try to keep it in a healthy range (below 40 inches for men, according to medical advice).
Eat a Balanced Diet: A diet containing high fiber, lean protein, and healthy fats can assist in limiting visceral fat gain.
Exercise Consistently: Regular exercise with a combination of aerobic and strength training will help maintain a healthy waistline.
Control Stress and Sleep: Persistent stress and inadequate sleep tend to cause weight gain, especially in the midsection of the body.
Regular Health Screenings: Early identification of cancer risk factors through regular screening can greatly enhance long-term health status.
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American TV personality Oprah Winfrey turned heads at the Paris Fashion Week with her slim figure and sparked talks on the popular weight-loss drug Ozempic.
The now viral videos show Oprah, 72, in jeans and a jacket. Usually seen in parted hair, Oprah also resorted to a ponytail and was wearing tinted sunglasses.
While several netizens expressed concerns about her health, others also spoke about the effects of Ozempic, widely used for weight loss.
“What in the Ozempic Oprah is going on here?”, wrote a user.
“I'm afraid Oprah may OD on Ozempic. Welfare check, please!” another added.
People also commented on the seemingly bigger head and frail body.
“Her head looks way too big for her body. Is it Ozempic or Oprah?” wrote a user.
“She looked good, but she seemed frail,” the netizens said, while another stated, “But having a head that big still is crazy”.
The video also showed Gayle King, another TV host and a longtime friend of Oprah, with a lean figure. Gayle, 71, also rocked a warm-brown look, paired with a fitted top and a black leather jacket.
Oprah has openly shared the use of a GLP-1 agonist for weight loss. However, she never mentioned any brand names.
“One of the things that I realized the very first time I took a GLP-1 was that all these years I thought that thin people just had more willpower, they ate better foods, they were able to stick to it longer, they never had a potato chip, and then I realized the very first time I took the GLP-1 that, 'Oh, they're not even thinking about it. They're only eating when they're hungry, and they're stopping when they're full,” Oprah said in a podcast early in 2025.
In 2023, speaking to People, she said she uses the weight-loss medication as a tool to quiet the food noise.
“I now use it as I feel I need it, as a tool to manage not yo-yoing. It quiets the food noise,” she had told the publication.
In an Instagram post in February 2026, Oprah also showcased her strength training evolution, highlighting the benefits of daily workouts for bone health and her impressive plank progress.
She told her fans that while in 2024, she struggled to hold a plank for more than 10 seconds, now she manages to do a 1-minute plank routine.
While Ozempic was originally developed and FDA-approved as an injectable medication to help manage type 2 diabetes, it has gained immense popularity for its ability to produce significant weight loss.
The drug is popular for its active ingredient, semaglutide, which works by mimicking a hormone that regulates blood sugar and appetite.
However, there are several concerns over its side effects. The loss of lean mass, which includes muscle, has emerged as the biggest concern.
Studies have proven that it provides significant weight loss and also reduces major cardiovascular risks and boosts kidney health, among others.
However, common side effects include:
gastrointestinal (nausea, vomiting, diarrhea, constipation),
pancreatitis,
gallbladder issues,
face sagging
dental issues like tooth decay, erosion.
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She wakes before dawn, packs lunches, manages households, holds careers together, and still finds time to ask everyone else, "Are you okay?" The Indian woman is, in every sense, the backbone of her family. And yet, in giving so much of herself to others, she often becomes the last person she takes care of.
This International Women's Day, that needs to change.
Cancer remains one of the gravest health threats facing Indian women today.
Breast cancer has become the most frequently diagnosed cancer among Indian women — and unlike in Western countries, it is striking women in their 30s and 40s, at the very peak of their lives.
Cervical cancer, though almost entirely preventable, continues to claim thousands of lives every year — not because medicine has failed, but because awareness has.
Ovarian cancer, often called the "silent killer," is frequently caught only at advanced stages, making early vigilance all the more critical.
Thyroid cancer is emerging as a cancer that disproportionately affects women — occurring nearly three times more often in women than men. The good news is that it is also one of the most treatable cancers when detected early.
Women who notice a lump or swelling in the neck, unexplained hoarseness, or difficulty swallowing should not dismiss these signs.
A simple ultrasound and blood test can go a long way in ruling out — or catching — a problem early. The truth, however, is not bleak — it is urgent.
Most cancers, when found at an early stage, are highly treatable. Women above 40 should schedule regular clinical breast examinations and mammography.
Cervical cancer screening through a Pap smear or HPV test, starting as early as age 25–30, can detect precancerous changes before they ever become cancer. These tests are quick, safe, and available — what they need most is for women to simply show up.
Prevention, too, begins with everyday choices. Avoiding tobacco in all its forms — cigarettes, gutka, paan — is the single most powerful step. Regular physical activity, a diet rich in fruits and vegetables, maintaining a healthy weight, limiting alcohol, and getting the "HPV vaccine" (ideally between ages 9 and 14) can dramatically reduce cancer risk.
And perhaps just as importantly: listen to your body. An unusual lump, unexplained bleeding, or a symptom that won't go away is not something to push aside for later. Later can cost everything.
A healthy woman builds a healthy family — and a healthy nation. This Women's Day, let's give every woman around us the most meaningful gift possible: the reminder that her health is not selfish, it is essential.
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The 20th-century modernist writer Virginia Woolf, in her book 'Mrs Dalloway', published in 1925, described her 52-year-old protagonist Clarissa Dalloway feeling “shriveled, aged, breastless”, during menopause.
Even after decades, the experience continues to remain widely relatable for scores of women worldwide.
In January this year, author Twinkle Khanna compared menopause to “a phone with a faulty charger.” Several other celebrities, namely Naomi Watts, Oprah Winfrey, Gwyneth Paltrow, and Angelina Jolie, have voiced out their concerns and frustration that women face during the transition.
Menopause is a natural transition in a woman’s life, typically occurring between the ages of 45 and 55. But for millions of women around the globe, its symptoms, which range from hot flashes to night sweats to mood changes and sleep variations, can wreak havoc, affecting professional life, relationships, and physical and mental health.
Hormone replacement therapy (HRT) can be the answer to help ease the symptoms, which are often misunderstood, under-discussed, and sometimes unnecessarily feared.
“Hormone Replacement Therapy (HRT) is an evidence-based option that helps restore hormonal balance during this transition. It is highly effective in relieving menopausal symptoms, improving quality of life,” Dr. Parjeet Kaur, Associate Director, Endocrinology & Diabetes, Medanta, Gurugram, told HealthandMe.
Menopause marks the end of reproductive years for a woman. It occurs when a woman permanently stops menstruating.
Clinically, menopause is diagnosed after 12 consecutive months without a menstrual period.
Most women experience menopause between the ages of 45 and 55, though the transition -- called perimenopause -- can begin several years earlier.
During this time, the ovaries gradually produce less estrogen and progesterone, the hormones that regulate the menstrual cycle. This hormonal decline leads to a range of symptoms, which vary widely among women.
“Menopause is a natural part of biological ageing. It can also be due to medical or surgical procedures. Most women go into menopause between 45 and 55 years,” Dr. Shilpa Agarwal, Consultant Gynecology and Obstetrics and Fetal Medicine Expert, Jaslok Hospital and Research Centre, Mumbai.
“Menopause is caused by the loss of ovarian follicular function and, consequently, a decline in the circulating blood estrogen levels. Natural menopause is deemed to have occurred after 12 consecutive months without menstruation for which there is no other obvious physiological or pathological cause and in the absence of clinical intervention,” she added.
Common symptoms include:
While some women experience only mild symptoms, others find that menopause significantly affects their quality of life.
More than the uncomfortable symptoms, the drop in estrogen levels raises a slew of health issues, mainly osteoporosis, heart disease, and sometimes metabolic disorders.
Although regular health checkups, balanced nutrition, and physical activity during midlife are essential to sail through, HRT can play a huge role.
Hormone replacement therapy consists mainly of female hormones, typically estrogen alone or a combination of estrogen and progesterone.
Former First Lady of the US, Michelle Obama, in her podcast in 2020, spoke candidly about her experience of hot flashes.
She described it as a "furnace turning on in her core", and a host of other issues after which she resorted to HRT to maintain her health and lifestyle during that transition.
“Hormone replacement therapy replenishes women with ovarian hormones. HRT typically combines estrogen and progesterone therapy. Progesterone is required in women with an intact uterus to prevent endometrial hyperplasia,” Dr. Agarwal said.
The medications primarily help in
Dr. Kaur said that HRT is highly effective in relieving menopausal symptoms, improving quality of life, and supporting bone health by reducing the risk of osteoporosis.
Notably, it can be used in several forms, including pills, skin patches, gels, sprays, and vaginal creams or rings.
Dr. Agarwal recommended that women start HRT within 10 years of menopause or before the age of 60 years".
The experts also advised women to keep monitoring for side effects during HRT.
For many women with moderate to severe menopausal symptoms, HRT can be highly effective.
Studies show that beyond hot flashes, improving sleep, and restoring vaginal health, hormone therapy also
leads to:
Despite its benefits, HRT has been the subject of debate for decades. Safety concerns intensified after a major US study in the early 2000s linked certain types of hormone therapy to increased risks of breast cancer, blood clots, and stroke.
However, in 2025, the US FDA removed all misleading warnings on the therapy.
Current medical guidelines generally suggest that HRT is safest for healthy women under age 60 or within 10 years of menopause, when used at the lowest effective dose for symptom relief.
“Modern HRT, when carefully selected and monitored, is considered safe for many women. The key is individualized care -- a thoughtful discussion with your doctor can help determine the most suitable approach based on your health profile, age, and personal preferences,” Dr. Kaur said.
Still, HRT may not be advisable for women with a history of:
For these women, non-hormonal treatments -- such as certain antidepressants, lifestyle changes, and alternative medications -- may help manage symptoms.
Menopause is a new phase of life -- and with the right information and guidance, it can be navigated confidently and comfortably, Dr. Kaur said.
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