When was the last time you measured your waistline? If you assume that BMI is the only number to focus on when it comes to your health, think twice. New research has revealed a shocking revelation—your waist circumference might be a far better predictor of men's cancer risk than BMI.

The study finds that for each 4-inch increase in waist size, a man's risk of cancer increases by a staggering 25%. Meanwhile, BMI, commonly regarded as the gold standard for assessing obesity, raises cancer risk by only 19% for the same weight gain. So, if you've been dismissing that pesky belly fat, it's time to take notice.

But why is your waistline so important? The reason is visceral fat—the hidden, deep fat that accumulates around your organs. Unlike other body fat, visceral fat is a stealthy troublemaker, causing inflammation, insulin resistance, and abnormal blood fat levels—all of which combine to create a cancer-perfect storm.

Obesity has been associated with an increased risk of numerous health conditions, including cancer, for decades. The research, though, indicates that a specific measure of the body—waist circumference—may be an even more reliable forecaster of cancer risk in men than the more frequently employed Body Mass Index (BMI). This finding emphasizes the need to pay particular attention to the distribution of fat and not merely to the weight of the body.

BMI has been the go-to measure for years for gauging health risks related to obesity. New research, though, that appears in The Journal of the National Cancer Institute indicates that waist measurement is a better predictor of cancer risk in men. According to the research, four more inches (10 cm) around the waist will add 25% to a man's cancer risk. Conversely, a 3.7 kg/m² rise in BMI (from a BMI of 24 to 27.7) increased cancer risk by only 19%.

Why is waist circumference a better predictor, then? Unlike BMI, which measures weight relative to height, waist circumference actually measures abdominal fat—specifically, visceral fat. This type of fat encircles internal organs and is also linked to higher levels of inflammation, insulin resistance, and abnormal blood lipids, all of which are factors in cancer growth. BMI, however, does not measure fat distribution, so two individuals with the same BMI can have very different levels of health risk depending on where fat is deposited on their bodies.

Why Men Are at Higher Risk?

Interestingly, the research identified a significant difference between men and women when it came to waist circumference and cancer risk. Although waist circumference and BMI were linked with obesity-related cancers in women, the relationship was weaker than for men. An increase of 12 cm (4.7 inches) in waist size or a 4.3 rise in BMI (from 24 to 28.3) raised the cancer risk in women by just 13%—a much lower percentage than for men.

Experts credit this difference to the way that fat is stored in the body. Men are more likely to carry fat around the abdomen, especially as visceral fat, which is more metabolically active and associated with cancer-producing biological alterations. Women, by contrast, store fat in peripheral sites such as the hips and thighs, where it is less likely to drive systemic inflammation and metabolic disturbances.

A possible reason is that men tend to depot fat more in the visceral regions, whereas women tend to carry more subcutaneous and peripheral fat," wrote the researchers. "This may render waist circumference a more robust risk factor for cancer in men and account for why waist circumference provides additional risk information beyond BMI in men but not women."

Cancer Types Most Linked to Abdominal Fat

The research used the International Agency for Research on Cancer (IARC) data to define obesity-related cancers. These cancers are esophageal (adenocarcinoma), gastric (cardia), colorectal, rectal, liver, gallbladder, pancreatic, renal, and thyroid cancers, and multiple myeloma and meningioma. In men, abdominal obesity is especially significant in raising the risk of these cancers through high levels of insulin and markers of inflammation.

For women, the research proposes that both waist circumference and hip circumference may give a more accurate estimate of visceral fat and cancer risk. "Adding hip circumference to risk models could strengthen the link between waist circumference and cancer, especially in women," researchers observed.

What This Means for Men's Health and Cancer Prevention?

With these results, doctors advise men to be more mindful of their waistline than only their BMI. Waist size is an easy method to gauge health risk, and its maintenance through lifestyle changes might be the key to cancer prevention.

How To Reduce Cancer Risk In Men?

Track Your Waist Size: Regularly measure your waist circumference and try to keep it in a healthy range (below 40 inches for men, according to medical advice).

Eat a Balanced Diet: A diet containing high fiber, lean protein, and healthy fats can assist in limiting visceral fat gain.

Exercise Consistently: Regular exercise with a combination of aerobic and strength training will help maintain a healthy waistline.

Control Stress and Sleep: Persistent stress and inadequate sleep tend to cause weight gain, especially in the midsection of the body.

Regular Health Screenings: Early identification of cancer risk factors through regular screening can greatly enhance long-term health status.

When we think of perimenopause, irregular periods, hot flashes and mood changes usually come to mind. But the transition to menopause is not limited to the menstrual cycle. Behind the scenes, changing ovarian hormones—particularly fluctuating and eventually declining estrogen—can influence body composition, insulin sensitivity, cholesterol levels, bone health and cardiovascular risk.

For many women, these metabolic changes begin years before their final menstrual period.

Why does weight suddenly behave differently?

A common concern during perimenopause is: “I haven’t changed my diet, so why am I gaining weight around my abdomen?”

Ageing itself contributes to gradual loss of muscle mass and changes in energy expenditure. At the same time, the menopausal transition is associated with a shift in fat distribution, with a greater tendency to accumulate visceral or abdominal fat.

This matters because visceral fat is metabolically active. An increase in abdominal fat can be associated with insulin resistance, abnormal cholesterol levels and a higher risk of metabolic disease. So, the change in waist circumference may sometimes tell us more about metabolic health than the number on the weighing scale alone.

Also read: After Menopause, These Breast Changes Shouldn’t Be Ignored

Blood sugars may raise up too

Estrogen interacts with several pathways involved in glucose and fat metabolism. During midlife, changes in body composition, reduced physical activity, sleep disturbance and hormonal changes can collectively make insulin sensitivity less favourable.

This does not mean every woman going through perimenopause will develop diabetes. However, women who already have risk factors—such as overweight or obesity, prediabetes, a history of gestational diabetes or a strong family history of type 2 diabetes—should be particularly mindful.

Cholesterol and heart health deserve attention

The menopausal transition can also be accompanied by unfavourable changes in the lipid profile, including changes in LDL cholesterol. Cardiovascular risk increases with age, and menopause is an important time to reassess risk factors such as blood pressure, glucose, cholesterol, smoking, physical activity and body composition.

Women often spend years focusing on reproductive health while overlooking these equally important metabolic markers.

Also read: World Menopause Day: Is It Empty Nest Syndrome Or Menopause Symptoms? Expert Explains

Muscles and bones need attention as well

Midlife is also an important period for protecting muscle and bone. Declining estrogen after menopause accelerates bone loss, while ageing contributes to loss of muscle mass.

Resistance training therefore becomes especially valuable. Adequate protein intake, regular weight-bearing exercise, sufficient calcium and vitamin D, good sleep and avoiding smoking can support healthier ageing.

What should women do?

Perimenopause should not be viewed as a disease, nor should every symptom or kilogram gained in midlife automatically be blamed on hormones. Instead, it is an opportunity for a metabolic health check.

Women should discuss appropriate screening for blood pressure, blood glucose or HbA1c, lipid profile, weight and waist circumference monitoring , DEXA scan for bone health, depending on their individual risk factors.

Most importantly, don’t wait for menopause to start thinking about metabolic health. The perimenopausal years can be an important window to build muscle, improve fitness, optimise nutrition and identify metabolic risk early.

Perimenopause is more than a change in periods—it is a transition in whole-body health. Understanding these changes early can help women enter the next phase of life stronger, healthier and better prepared.

(By Dr. Seema Daksh, MBBS, MD (Internal Medicine), DM (Endocrinology), Consultant Endocrinologist,Kailash Hospital, Greater Noida)

From haunted houses and sudden scares to sweet treats and costumes, Halloween fun can come with hidden health risks, particularly for people with existing heart and lung conditions.

Experts explain how sudden fright, excessive sugar and common activities on Halloween, observed on October 31, can affect heart and lung health.

How Sudden Scares Can Affect Your Heart

A sudden scare activates the body's sympathetic nervous system, raising heart rate and blood pressure while constricting blood vessels.

This response is usually harmless in healthy people, but may pose risks for those with arrhythmias, coronary artery disease or a history of stents or heart surgery.

A racing heartbeat should settle after the scare. Persistent palpitations, dizziness, shortness of breath, chest pain or tightness, nausea, sweating or fainting warrant medical attention, says Dr Mohamed Gabr, cardiologist and electrophysiologist at Baylor College of Medicine.

In addition, excessive consumption of sugar candies during Halloween can contribute to obesity, diabetes, high blood pressure and unhealthy cholesterol levels. Cholesterol and plaque buildup in the coronary arteries can begin at a young age.

Also read: You Feel Healthy. But Plaque May Already Be Building In Your Arteries In Your 20s

Halloween Activities That Can Trigger Asthma

Halloween activities can expose people with asthma to several triggers. Ragweed pollen, mould on damp fallen leaves and cold, dry air can worsen symptoms during autumn, according to the American Lung Association.

Fog machines and dry ice effects in haunted houses can release water droplets and chemicals, including glycol-based solvents, that may irritate airways. Glitter machines, bonfire smoke, dust from stored costumes and decorations, and strong fragrances can also trigger symptoms.

Dr Rubabin Tooba, a pulmonologist with Northwestern Medicine, says these exposures may cause coughing, wheezing, breathlessness and chest tightness, particularly in people with asthma, severe allergies or COPD. Tight-fitting masks can also make breathing difficult.

Fear, excitement and laughter may trigger asthma symptoms in some people. Trick-or-treating can bring additional exposure to pet dander, scented candles, cigarette smoke and fireplace fumes.

Pumpkin Carving And Halloween Injuries

Read More: Why Are Asthma Cases Rising Among Young Kids? Early Symptoms Parents Must Not Ignore

The US Consumer Product Safety Commission (CPSC) estimates that an annual average of 3,200 Halloween-related injuries were treated in US emergency departments over a recent three-year period.

Pumpkin carving accounted for 55% of these injuries, while 25% were related to falls while putting up decorations, tripping on costumes or walking while trick-or-treating. The remaining 20% involved lacerations, ingestions, allergic reactions and other costume- or decoration-related injuries.

Children younger than 18 years accounted for 46% of injuries, with approximately 10% occurring in children aged 6 years or younger.

The Plastic Hand Trauma Unit at Royal Devon and Exeter Hospital has also treated patients with deep cuts, severed tendons and nerve damage from pumpkin carving, BBC reported.

How Can You Stay Safe This Halloween

• Protect your heart: Be mindful of sudden scares if you have an existing heart condition. Seek medical attention for persistent palpitations, chest pain, breathlessness or fainting.

• Moderate candy: Limit sugary treats and consider fruit alternatives.

• Avoid asthma triggers: Ask about fog effects at haunted attractions and leave if you experience breathing discomfort.

• Check costumes and decorations: Clean stored items before use and discard anything with mould or a musty smell. Choose breathable, open-face masks.

• Use makeup carefully: Choose fragrance-free or hypoallergenic products and apply them in well-ventilated spaces.

• Carry asthma medication: Keep your prescribed quick-relief inhaler and spacer handy. Watch for coughing, wheezing or chest tightness, and take breaks when needed.

• Reduce infection risks: Practise good hand hygiene, stay home when sick and keep vaccinations up to date.

• Carve pumpkins safely: Avoid kitchen knives. Use pumpkin-carving kits with serrated tools and make small, controlled cuts.

When a couple has difficulty conceiving, thyroid checks are among the first things doctors do. Yet, it is an important fact that one often forgets - overt hypothyroidism or mild/subclinical hypothyroidism are actually very different things.

Having a thyroid that is not active enough means the body is not producing enough thyroid hormones. These hormones regulate metabolism and at the same time can greatly affect the functioning of the reproductive system like the occurrence and regularity of the menstrual cycle, ovulation and the hormonal environment that is necessary for pregnancy. Still, new findings suggest that we should not always take the blame for infertility just because the TSH level is borderline or abnormal.

When hypothyroidism genuinely affects fertility

Undiagnosed, overt hypothyroidism has the potential to disrupt reproduction in many ways. Lower levels of thyroid hormones may alter the balance in hypothalamic-pituitary-ovarian axis, which would affect ovulation and menstruation. In severe cases of hypothyroidism, higher prolactin levels could be observed, disrupting endocrine signaling.

According to new 2026 American Thyroid Association guidelines, overt hypothyroidism is considered to be a known risk factor for infertility and recurrent miscarriages. Specifically, according to the guideline, menstrual problems have been seen in 23% of women with untreated overt hypothyroidism, and about 2–3% of all cases of anovulation are due to hypothyroidism.

It is important to note that women with known hypothyroidism, who received appropriate treatment with levothyroxine and were in a euthyroid state, had the same chances for fertility as women without thyroid disorder.

Thus, the message here is not that women with hypothyroidism are unable to conceive. It is that thyroid dysfunction should not go untreated during planning of pregnancy.

Also read: World Iodine Deficiency Day: Significance And Importance

But what about a mildly raised TSH?

This is where the science becomes considerably more interesting.

Subclinical hypothyroidism generally means that TSH is elevated while free T4 remains within the normal range. It is increasingly detected during fertility investigations, partly because women are being tested more frequently.

But does every mildly elevated TSH require treatment?

A 2025 review article published in Current Opinion in Obstetrics & Gynecology concluded there isn't enough reliable evidence at this time to consider subclinical hypothyroidism as a contributor to infertility. It was also found that the use of levothyroxine was not consistently tied to improved pregnancy or live-birth outcomes in women suffering from subclinical hypothyroidism. The authors advocated for screening and treatment practices that are selective rather than universal.

This new recommendation represents a clear departure from the previous approach that was often overly aggressive in treating women with marginal thyroid test results.

The same findings were reported in a randomized trial-based 2024 systematic review and meta-analysis, which was published in a leading international medical journal by the world's largest academic medical publisher. The analysis showed that preconception levothyroxine administration had no statistically significant effect on live birth rates or pregnancy or miscarriage rates in subclinical hypothyroid women. Still, it should be mentioned that the scientists have recognized this issue and they have pointed out that for women with a TSH level above 4 mIU/L, the evidence is even more uncertain and that better trials are needed.

Also read: World Menopause Day: Is It Empty Nest Syndrome Or Menopause Symptoms? Expert Explains

New 2026 IVF data add another layer

A quite relevant study published in Human Reproduction in July of the same year examined 412 women who were subclinically hypothyroid and had frozen embryo transfers. In this group, 198 got levothyroxine whereas the other 214 were untreated. The live-birth rates were 43.9% for levothyroxine users against 39.3% in the untreated group. Even though the numbers were better for the treated group, the difference was not statistically significant.

It is also remarkable that apart from the levothyroxine group, they got other embryological results as well, including more fertilised oocytes, Day-3 embryos, good-quality Day-3 embryos and blastocysts. Yet it didn't lead to statistical significance of the live births. It's a typical point in fertility medicine that even if lab or embryological indicators are enhanced, it doesn't necessarily mean having more children.

In addition, the study carried out in 2026 on women undergoing the procedure of assisted reproduction, who left untreated, revealed that women with untreated TSH between around 3.6 and 6 mIU/L retrieved fewer oocytes. Yet, the live-birth rates after accounting for other factors turned out to be no significant difference at all (1,2).

In fact, there was quite a relevant study carried out recently on the effect of levothyroxine on the frozen embryo transfer (FET) outcomes in cases of subclinical hypothyroidism. It was conducted in Human Reproduction in July 2026. The participants of the study were 412 hypothyroid women who were undergoing FET (frozen embryo transfer).

Does thyroid disease affect egg quality?

Some evidence is emerging from here, but it should not yet be presented as an undisputed scientific fact.

On a big research scale with 2,867 women who were in the first IVF treatment cycle, it turned out that women who had subclinical or even overt hypothyroidism had their ovarian function decline much more than normal women, which was assessed through AMH and antral follicle count independent of thyroid autoimmunity. Though being an observational study, it just indicates the presence of a connection but not that hypothyroidism is causing the ovarian reserve to diminish.

The reason for drawing up such a clear line between them is that fertility depends on age, female factors like ovarian reserve, endometriosis PCOS, tubal factors, male factors like sperm quality, metabolic health and many other variables. Thyroid function is just one aspect out of a large puzzle not the complete picture

What about Hashimoto's and thyroid antibodies?

Thyroid autoimmunity is another contributing factor. There are cases where some females have thyroid antibodies, specifically thyroid peroxidase antibodies, even when the thyroid hormones of the individual are within normal range.

There is an inconclusive body of evidence associating the existence of thyroid antibodies with difficulty conceiving. In a review conducted in 2025, there was no substantial evidence that would support routine screening for every infertile female. The more recent 2026 ATA guidelines highlight the importance of taking into consideration the individual needs of the patient.

So, should every woman trying to conceive have a thyroid test?

Not necessarily in exactly the same way.

A thyroid assessment is particularly important for women with a previous thyroid disorder, symptoms suggestive of hypothyroidism, irregular menstrual cycles, infertility, recurrent pregnancy loss, autoimmune disease or a family history of thyroid disease.

Recent Indian health coverage has also highlighted the importance of checking thyroid function during preconception care. A January 2026 Hindustan Times report noted the association between thyroid dysfunction and menstrual irregularities, infertility and recurrent miscarriage, while recommending greater awareness around testing during preconception and early pregnancy.

The bottom line

Thyroid gland is the most misused organ when it comes to health, Mainly when it comes to treatment.

When a woman suffers from uncorrected overt hypothyroidism, this can clearly interfere with fertilization by causing ovulation and monthly cycle irregularities and affecting fertility generally, which needs to be corrected before pregnancy whenever it is feasible. Generally, fertility results are encouraging after thyroid hormone levels are kept within the normal range.

In case of very mild to subclinical hypothyroidism In particular when the TSH is only a little bit above the normal levels and free T4 remains stable, the situation is far from a textbook case and it is rather a grey zone. However, new research conducted in 2025 and 2026 increasingly supports the idea of going beyond a one-size-fits-all prescription of levothyroxine to women with borderline TSH.

The only reasonable course of action for a woman who wants to conceive is as simple as: assess thyroid function clinically only when it is necessary (i.e., when there are clinical signs/symptoms of thyorid imbalance/ disease). Determine if the imbalance is one of those that are clinically overt (like signs and symptoms of overt hypothyroidism, elevated TSH, etc.) or clinically subclinical, then consider the TSH level, symptoms, thyroid antibodies, reproductive history, etc., and refer the treatment to an endocrinologist or fertility specialist to decide.

The goal is not to chase an arbitrary “perfect” TSH number. The goal is to identify genuine thyroid disease, treat it appropriately and avoid allowing either an untreated disorder or unnecessary treatment to become another source of anxiety during an already stressful fertility journey.