US Doctor Claims Weight Loss Drug, GLP-1, Leads To Suicidal Thoughts And Behaviors

Updated Jan 16, 2025 | 10:56 AM IST

SummaryA study found that disruptions in homeostasis from quick weight reduction by consuming GLP-1 drug can elevate cortisol - a steroid hormone, also known as the stress hormone and norepinephrine levels - linked to anxiety, which increases your heart rate and blood pressure.
Weight loss Glp-1 drug leads to suicidal thoughts and behaviors

The American celebrity doctor, Daniel Gregory Amen, who practices as a psychiatrist and brain disorder specialist in his recent Instagram (doc_amen) video claimed the link between GLP-1 drugs and suicidal thoughts.

"There is brand new research that is concerning regarding the GLP-1 Drugs like Ozempic, commonly used to treat diabetes and obesity," he said. He then went on to cite the Journal of Affective Disorder for their recent study that explored the connection between these medications and suicidal thoughts and behaviors.

He said, "The researched reviewed reports in a very large World Health Organization database. The medication showed up to a 5-fold increase in suicidal thoughts and behaviors."

However, he did go on to say that these findings do not establish a direct cause and effect relationship. However, if you are taking it, you and your healthcare provider must monitor your mental health. In case of any changes in your moods and motivation, you must tell your healthcare provider.

What are GLP-1 Drugs?

They are a class of medications that help manage the blood sugar (glucose) levels in people with Type 2 obesity. Some GLP-1 agonists can also help treat obesity.

They are most often injectable medication, which means you inject a liquid medication with a needle and syringe. The shot is administered in the fatty tissue under your skin and areas of your body that includes your belly, outer thighs, upper buttocks, and the back of your arms.

The Food and Drug Administration (FDA) first approved GLP-1 Drugs in 2005 and research is still on going about their potential use and benefits.

ALSO READ: Semaglutide Drugs Ozempic, Wegovy Don’t Increase Suicide Risk Or Depression, Study Finds

How Does It Work?

GLP-1 is a hormones that your small intestine makes which can do these following functions:

  • Trigger insulin release from your pancreas
  • Block glucagon secretion (glucagon is a hormone that your body uses to raise your blood sugar levels when necessary)
  • Slows stomach emptying: slower digestion means your body releases less glucose from food to your bloodstream
  • Increase your satiety

Is There Any Direct Links Between GLP-1 And Suicidal Thoughts

As per the Lancet Study titled Suicide and suicide attempt in users of GLP-1 receptor agonists: a nationwide case-time-control study, GLP-1 drug use was not associated with an increased risk of suicide or suicide attempt.

The study analyzed 1102 cases and 5494 control, with the mean age as 57.4, with 44.6% being men, 67.6% with recent psychiatric history and 51.3% with obesity.

However, another study titled GLP-1 agonists and risk of suicidal thoughts and behaviours: Confound by indication once again? A narrative review that reviewed the potential link of GLP-1 drug to psychiatric side effects found that these drugs can introduce biological and psychological stressors.

The study found that disruptions in homeostasis from quick weight reduction can elevate cortisol - a steroid hormone, also known as the stress hormone and norepinephrine levels - linked to anxiety, which increases your heart rate and blood pressure. However, the study noted that there is insufficient evidence for a direct causal link between GLP-1 drug and suicidal thoughts and behaviors (STB).

The study notes: "The indirect effects related to the metabolic and psychological disturbances associated with rapid weight loss call for a cautious approach. Used carefully in targeted populations GLP-1 agonists may even emerge as protective agents against STB. Therefore, it is crucial to monitor patients during the treatment and screen for preexisting mental health conditions. If detected, appropriate clinical management should be applied."

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Don't Ignore These Cancer Symptoms: Oncologist Shares The Early Warning Signs

Updated Jul 4, 2026 | 11:00 AM IST

SummaryCancer is often diagnosed late in India. Dr. Hasmukh Jain urges people to seek medical care for persistent symptoms lasting over two weeks to enable earlier detection.
Don't Ignore These Cancer Symptoms: Oncologist Shares The Early Warning Signs

Credits: Canva

Cancer cases are rising across India, but many patients still reach hospitals only after the disease has advanced. According to Dr. Hasmukh Jain, Professor of Medical Oncology at Tata Memorial Hospital, Mumbai, recognizing persistent warning signs and seeking timely medical care can make a critical difference.

Speaking about cancer awareness, Dr. Jain said, "Every year 15 lakh new cases of cancer are diagnosed in India. But the unfortunate thing is that most of these cases are diagnosed at an advanced stage."

He stressed that while cancer can present in many different ways, paying attention to your body's signals is one of the most important steps toward early diagnosis.

Persistent Symptoms Should Never Be Ignored

Dr. Jain explained that cancer often begins with symptoms that are common to many other illnesses, making them easy to dismiss. These may include:

  • Unusual or persistent fatigue
  • A cough lasting more than two weeks
  • Unexplained weight loss
  • Bleeding from the nose or other parts of the body
  • Fever lasting more than two weeks
Persistent pain that does not improve with rest

Although these symptoms may also occur due to infections or conditions such as tuberculosis, he advised against ignoring them.

"If the symptoms are persisting for more than two weeks, always seek medical attention," Dr. Jain said.

He added that many cancers can be detected through a physical examination, basic blood tests, and, when required, a biopsy.

Also Read: FSSAI Targets 6 Energy Drink Brands; Experts Link Them to Obesity, Liver Problems

Everyday Habits That Can Reduce Cancer Risk

Cancer cases are increasing at an alarming rate, both in India and globally. To combat this, embracing healthy lifestyle practices can significantly reduce the risk of this life-threatening disease.

Here are some of the everyday habits that one can follow to reduce the risk of cancer:

Maintain A Healthy Diet

Consuming a healthy and balanced diet rich in fruits, vegetables, whole grains, and lean proteins can reduce cancer risk. Berries, nuts, and green leafy vegetables contain many antioxidant properties that are useful in fighting oxidative stress-induced cancer. Cutting back and eliminating red and processed meat and sugar-containing drinks lowers the risk further.

Stay Physically Active

Regular physical activity keeps the individual body fit and reduces the risk of breast, colon, and endometrial cancers.

Avoid Tobacco And Cut Down On Alcohol Consumption

Among the factors that would be measured when determining preventable causes, tobacco use takes part as the first head in the index, associated with lung, throat, or mouth cancers. Similarly, alcohol consumption exposure is linked to many cancers, from hepatocellular to breast cancer. Moderation or abstinence is the key.

Protect Your Skin From The Sun

Skin cancer is one of the most preventable types of cancer. Applying sunscreen with high SPF, finding shade, and avoiding tanning beds would save you from harmful ultraviolet rays.

Get Regular Screenings

Most people, including men and women over the age of 40, should get routine screening through mammograms, Pap tests, and colonoscopy to enhance early detection, which can save lives.

Moreover, cancer prevention is a shared goal influenced by personal choices. Bringing small yet steady changes in daily habits can dramatically reduce cancer risk while enhancing quality of life.

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Swimming Injuries In Children And Adults: 7 Physiotherapist Tips To Stay Pain-Free In The Pool

Updated Jul 4, 2026 | 09:00 AM IST

SummarySwimming offers excellent health benefits, but poor technique, skipped warm-ups, and overtraining can cause injuries. Proper preparation, gradual progression, and good form help prevent them.
Swimming Injuries In Children And Adults: 7 Physiotherapist Tips To Stay Pain-Free In The Pool

Credit: AI Created Image

Swimming is often considered one of the safest forms of exercise—and for good reason. It provides an excellent cardiovascular workout, builds muscle strength, and places far less stress on the joints than activities like running or weight training. However, "safe" does not mean "injury-proof."

Whether it's children learning their first strokes or adults swimming regularly for fitness, injuries can occur when technique is poor, training intensity increases too quickly, or warm-ups are skipped. The good news is that most swimming-related injuries can be prevented with a few simple habits.

According to Dr. Dharam P. Pandey, Director, APARC Health & Motion, Premier Chain of Physiotherapy and Rehabilitation Care Provider, understanding these risks and taking preventive measures can help swimmers of all ages enjoy the sport without unnecessary setbacks.

Common Swimming Injuries In Children And Adults

Swimming injuries often develop gradually due to repetitive movements rather than sudden accidents.

In children, the most common causes include poor stroke technique, repetitive motion, and pushing beyond their physical limits too early. Shoulder pain—commonly known as "swimmer's shoulder"—is one of the most frequently reported issues. Breaststroke swimmers may also experience knee pain, while lower back discomfort is another common complaint.

Adults face many of the same overuse injuries but are also more likely to develop muscle strains, neck pain, and muscle cramps. These problems are especially common among people returning to swimming after a long break or those who suddenly increase the intensity or duration of their workouts.

Also Read: FSSAI Targets 6 Energy Drink Brands; Experts Link Them to Obesity, Liver Problems

Never Skip The Warm-Up

Many swimmers assume that simply getting into the water is enough to loosen up the body. In reality, muscles and joints perform much better when they are prepared beforehand.

A proper warm-up should include a few minutes of stretching along with gentle movements for the shoulders, neck, and legs. Once in the pool, swimmers should begin with easy laps before increasing speed or intensity. This gradual approach significantly lowers the risk of muscle strains and overuse injuries.

Technique Matters More Than Distance

Swimming longer distances is not always better if the technique is incorrect.

Poor stroke mechanics can place unnecessary stress on the shoulders, knees, and spine. Children benefit from proper supervision while learning swimming techniques, ensuring they develop correct movement patterns from the beginning.

Adults experiencing recurring discomfort should also consider improving their stroke technique instead of simply pushing through the pain. Good technique not only improves efficiency in the water but also plays a major role in preventing injuries.

Prevention Is Better Than Recovery

Swimming is an activity that people should be able to enjoy throughout their lives. Preventing injuries is far easier than recovering from them.

Following proper technique, warming up before every session, progressing gradually, staying hydrated, and paying attention to early signs of pain can help both children and adults remain active, healthy, and injury-free throughout the swimming season.

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Alzheimer's May Be Detectable Years Before Symptoms, Says Neurology Expert

Updated Jul 3, 2026 | 08:00 PM IST

SummaryAdvanced brain imaging and blood-based biomarkers are offering new hope for detecting Alzheimer's disease before symptoms appear, enabling earlier intervention, personalized care, and better brain health outcomes.
Alzheimer's May Be Detectable Years Before Symptoms, Says Neurology Expert

Image credits: Canva

Alzheimer's disease is one of the most prevalent types of dementia, and one of the biggest challenges is that the disease can begin many years before symptoms such as memory loss, confusion, or difficulty performing daily activities become noticeable. By the time these signs appear, important changes may have already occurred in the brain.

New hope comes from recent advances in diagnostic technologies. Scientists are developing specialized brain imaging techniques that can detect changes associated with Alzheimer's disease long before symptoms develop. These scans can identify abnormal protein deposits, such as amyloid and tau, which are known to play a key role in the disease process. Early identification of these changes may help doctors monitor individuals more closely and initiate timely interventions.

In addition to brain imaging, blood-based biomarkers are emerging as a promising tool for Alzheimer's screening. Recent research has shown that certain proteins linked to Alzheimer's disease can be detected through simple blood tests. While these tests are not yet a replacement for comprehensive evaluation, they may help identify individuals who require further assessment and could make early screening more accessible and affordable in the future.

These advanced tests are not currently recommended as routine screening for everyone, but they represent a significant step forward in early diagnosis and personalized care. Early detection may allow individuals to make informed life decisions, manage risk factors such as diabetes, hypertension, high cholesterol, and obesity, and potentially benefit from newer treatments that are most effective in the early stages before significant brain damage occurs.

Also Read: FSSAI Targets 6 Energy Drink Brands; Experts Link Them to Obesity, Liver Problems

Prevention, early detection, and timely intervention are the keys to the future of Alzheimer's care. As science advances, innovative imaging techniques and blood-based tests could help shift the focus from managing symptoms to identifying risk earlier and preserving quality of life. Early awareness and proactive brain health management remain our strongest tools in the fight against Alzheimer's disease.

Dr. Aparna Gupta, Director, Neurology, ISIC Multispeciality Hospital

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