A carnivore diet is a restrictive diet that only includes meat, fish, and other animal products like dairy and eggs. More recently, it has been brought into the limelight by influencers and social media personalities. In fact, there is a whole community of "meatfluencer" who are sharing their meat-eating plans. One of them is Dr Paul Saladino MD, whose belief that there was no better way to prevent chronic diseases than a carnivore diet prompted him to write books and post videos regarding the same. He believed so much in this eating plan that he became a go-to person for many following the same plan, until recently, when he decided to quit.

Here Are Seven Reasons Why He Decided To Quit

Carnivore Diet Disrupted His Sleep

Switching to an all-meat diet isn't always straightforward, especially when it comes to digestion—a lesson Dr Saladino learned firsthand. He experienced sleep disturbances, likely due to the difficulty of digesting high-protein meals. Since protein takes longer to break down, it demands more energy from the body, which can interfere with rest.

According to Johns Hopkins Medicine, digestion slows by up to 50% during sleep. Additionally, many types of meat contain tyramine, a compound derived from the amino acid tyrosine. Increased tyramine intake can lead to health issues and also triggers the release of norepinephrine, a hormone that raises heart rate and blood pressure, making restful sleep harder to achieve.

He also experienced hypnagogic jerks—sudden muscle spasms that jolt the body awake. "I would fall asleep but then jerk myself awake like I was falling multiple times. It was stressful and traumatic, leading to poor sleep," he shared in his YouTube video.

Eating Only Meat May Have Triggered Heart Palpitations

Another concerning side effect Dr Saladino experienced was heart palpitations—episodes where his heart felt like it was racing or fluttering. While stress is a common cause, few would immediately link palpitations to meat consumption.

However, a sudden shift to an all-meat diet can lead to electrolyte imbalances. The elimination of carbohydrates lowers insulin levels, prompting the kidneys to excrete more sodium. This disrupts the balance of essential minerals like potassium and magnesium, which are crucial for heart function.

Muscle Cramps Became Persistent

Dr Saladino also suffered from frequent muscle cramps while following the carnivore diet. In a post on X, he emphasized the importance of maintaining adequate magnesium, calcium, and potassium levels to prevent cramping. He initially believed that animal-based foods provided sufficient minerals, but his ongoing cramps led him to reconsider.

"I started to think maybe long-term ketosis is not great for me,” he admitted on the *More Plates More Dates* podcast. “Probably not a great thing for most humans."

His Testosterone Levels Dropped Significantly

Dr Saladino also saw a decline in his testosterone levels after following the carnivore diet for over a year. "At the beginning of my carnivore experiment, my testosterone was about 800. After a year to a year and a half, it had dropped to around 500," he revealed.

The issue likely stems from excessive protein intake, which can elevate inflammation and disrupt hormone levels. A 2022 study published in Nutrition and Health found that consuming more than 35% of daily calories from protein can lead to various negative effects, including reduced testosterone.

He Had Chronically Low Insulin Levels

Because he largely eliminated carbohydrates—except for a small amount of fruit—Dr Saladino developed persistently low blood sugar. In his YouTube video, he explained, "I had very low insulin because I wasn’t eating carbohydrates, and the protein I consumed wasn’t insulinogenic enough."

While some diabetics report improved blood sugar control on the carnivore diet, its effects vary based on individual metabolic responses. For non-diabetics, low insulin can lead to hypoglycemia, causing symptoms like dizziness, confusion, a racing heart, and, in extreme cases, seizures or coma. Mild cases can be managed with fast-acting carbohydrates like juice or candy, but severe episodes require medical attention.

His Blood Test Results Showed Concerning Imbalances

Lab tests revealed that his magnesium levels were low, while his sex hormone-binding globulin (SHBG) was elevated—both potential red flags for long-term health issues.

A magnesium deficiency can cause numbness, tingling, fatigue, nausea, headaches, and muscle cramps. Since cramps often strike at night, low magnesium may also contribute to sleep disturbances.

High SHBG levels indicate an excess of circulating protein in the blood, which can increase the risk of heart disease, osteoporosis, and depression. To counteract these imbalances, introducing more magnesium-rich foods—such as leafy greens, nuts, beans, and yogurt—could be beneficial.

He Felt Cold All The Time

Electrolyte imbalances and metabolic disruptions can even affect body temperature, which Dr. Saladino experienced firsthand. "I was always cold,"he shared in his YouTube video.

Upon testing his thyroid function, he discovered that his total T3 and free T3 hormone levels were "not ideal." These hormones regulate metabolism, and low levels can slow down metabolic processes, leading to cold intolerance.

Magic mushroom, a fascinating name, but the reason behind this naming is solely due to an active compound in that fungus called psilocybin. Notably, a single dose of it can easily reduce the nerve pain for months, thus has wide and effective use in painkillers according to a study recently done by the researchers from the University of Reading. This crucial study was published in Communications Biology.

The researchers used rats as test subjects to find this information. They injected psilocybin into mice with nerve damage. But within two hours, researchers found that the pain-relieving effect of psilocybin starts to relieve the pain in mice that had excruciating pain due to nerve damage. Though this was by no means the biggest finding of the study, it was also seen that the effect of the compound lasted for several weeks.

How Does Psilocybin Work As A Pain Reliever?

There is a very interesting explanation behind the long-lasting effect of Psilocybin. The active compound does not block the pain signal to the brain like other common pain relievers; instead, Psilocybin is likely to restructure the way the brain's pain-processing networks operate, which in turn ensures long-lasting effects of the compound even long after it exits the body.

What Is The Most Significant Finding Of The Study?

The study finds a great connection of mutual compatibility between psilocybin and gabapentin. Notably, gabapentin is a well-known drug commonly prescribed for nerve pain. In the aforementioned study, the researchers noticed that when gabapentin was given along with psilocybin, it produced pain relief lasting up to four days, but the effect when gabapentin was given alone was far weaker.

Dr Maria Maiarú, senior author from the University of Reading, said, "Millions of people live with nerve pain that their medication simply does not control well enough, and the medicines we do have can cause serious side effects or lead to addiction. What is exciting here is that psilocybin does not just reduce pain on its own. It appears to reset the brain's pain networks in a way that makes existing treatments significantly more effective. For patients who have run out of options, that could be genuinely transformative."

What Are The Other Crucial Findings In The Research?

Although initially the tests were done on the male mice, later on, the same compound was also injected into the bodies of female mice, and in both cases, the effect was complete success in achieving pain relief. The whole study was done with the aim of minimizing distress by using the 3Rs principles of Replacement, Reduction, and Refinement.

Why Is It called A Magic Mushroom?

The name is the direct result of its active compound, Psilocybin, which, when injected, can cause dream-like hallucinations, euphoria, and profound shifts in perception, mood, and consciousness.

Thyroid disorders don’t just affect women — it also affects men and raise fertility risks, said experts today on World Thyroid Day.

While thyroid disorders are commonly linked to symptoms such as weight gain, fatigue, mood swings, and hair loss, experts highlighted a lesser-known impact of thyroid imbalance — its effect on male fertility and reproductive health.

Dr. Piyush Lodha, Endocrinologist at Ruby Hall Clinic, Pune, told HealthandMe that both hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) can negatively affect sperm health and reproductive function in men.

“The thyroid regulates several important body functions, including metabolism and hormone balance. Even slight thyroid dysfunction can influence fertility because thyroid hormones are closely connected to reproductive hormones,” he explained.

How Thyroid Imbalance Affects Male Fertility

The doctors noted that thyroid hormones play an important role in sperm production, sperm maturation, libido, and sexual performance.

In hypothyroidism, reproductive processes may slow down significantly. Men may experience low testosterone levels, reduced libido, erectile dysfunction, and poor sperm quality.

Dr. Lodha noted that hypothyroidism can negatively affect sperm count, sperm motility, and sperm morphology, lowering the chances of successful conception. Fatigue, depression, and weight gain associated with thyroid disorders may further impact sexual health and self-esteem.

Hyperthyroidism can also affect fertility. Excess thyroid hormone may disturb the hormonal balance required for normal sperm production.

“In men, hyperthyroidism can lead to premature ejaculation, increased oxidative stress, and damage to sperm cells. In some cases, sperm concentration and semen volume may also decrease,” he said.

The expert warned that thyroid-related fertility issues often remain undiagnosed because symptoms develop gradually or are mistaken for stress and lifestyle-related problems.

Early Diagnosis Can Improve Outcomes

The expert stressed that timely diagnosis and treatment can significantly improve reproductive health.

“With hormonal therapy, dietary modifications, and regular monitoring, sperm health and reproductive function can improve over time,” Dr. Lodha explained.

He advised men experiencing unexplained infertility, sexual dysfunction, or persistent fatigue to undergo comprehensive reproductive health evaluations, including thyroid function tests.

Lifestyle Reasons Behind Surging Thyroid Disorders

Dr. Anu Mathew, Consultant Endocrinology, Fortis Hospital, Manesar, told HealthandMe that while women are more at risk, thyroid disorders can also affect men and children, and a lack of awareness often delays diagnosis.

She added that thyroid disorders are increasingly being linked to lifestyle-related factors, despite autoimmune disease remaining the most common cause.

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Dr. Anu pointed out that subclinical hypothyroidism (SCH) — characterized by elevated thyroid-stimulating hormone (TSH) with normal T3 and T4 levels — has shown strong associations with lifestyle factors in several studies.

“Both iodine deficiency and iodine excess have been associated with thyroid disorders. Lack of sleep, poor sleep quality, chronic stress, smoking, and sedentary lifestyles may also contribute to thyroid dysfunction,” she said.

According to experts, subclinical hypothyroidism has also been associated with increased risks of cardiovascular disease, insulin resistance, and metabolic syndrome.

The doctors, thus, stressed the importance of healthy lifestyle changes to prevent thyroid dysfunction and related complications.

When Thyroid Disorders Become Cancerous

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Dr. Manjunath NML, Senior Consultant – Surgical Oncology and Robotic & Laparoscopic Surgeon at HCG Cancer Hospital, Bengaluru, told HealthandMe thyroid cancer is often difficult to detect early because it grows slowly and may initially cause painless or nonspecific symptoms.

“Small thyroid nodules may go unnoticed because they are not always visible or palpable during routine examinations,” he explained.

Detection may become even more challenging in obese patients, where larger nodules can remain hidden.

Doctors also highlighted that cancerous nodules may sometimes be concealed within multinodular goitre, a condition commonly associated with iodine deficiency and more frequently seen among women in endemic regions.

Other reasons for delayed diagnosis include lack of awareness, socioeconomic barriers, and limited access to specialists and diagnostic technologies such as ultrasound and FNAC (fine needle aspiration cytology).

Experts noted that imaging tools like the TIRADS (Thyroid Imaging Reporting and Data System) scoring system play an important role in classifying thyroid nodules as benign, suspicious, or malignant, helping guide appropriate treatment decisions.

When people gain weight, the first thought often revolves around poor eating habits or a lack of physical activity in their daily routine. While that may be true, the cause of weight gain may be more than what meets the eye. One could have gained weight gradually despite the lack of significant changes in his/her lifestyle. In such cases, an underlying health condition such as a thyroid disorder could be contributing.

What Does The Thyroid Actually Do?

The thyroid is a small gland found in the neck region. But it plays a huge part in the body’s activities. This gland secretes hormones that control metabolism, i.e., the body’s capability to convert food into energy. The hormones released by the thyroid control many other body functions, including heart rate, body temperature, etc.

When the thyroid gland becomes underactive, a condition called hypothyroidism occurs, and it causes bodily functions to slow down. In turn, metabolism may be reduced, causing some alterations in people's well-being.

Weight Gain Is Often Not The Only Symptom

People suffering from hypothyroidism may experience other common symptoms besides weight gain, such as fatigue, lack of energy, constipation, dry skin, hair loss, mood swings, and intolerance to cold temperatures. However, thyroid-related weight gain is often misunderstood. It is usually gradual and may not always be dramatic. In many cases, the change can happen because of slowed metabolism and fluid retention.

Knowing When To Pay Attention

Not every person who gains weight has a thyroid problem, and not every thyroid patient experiences noticeable weight changes. Weight is influenced by many factors, including sleep, stress, age, and overall health.

However, if weight gain feels unexplained and is accompanied by other persistent symptoms, it may be worth seeking medical advice. Simple tests can help assess thyroid function and identify problems early. Sometimes, understanding the reason behind weight changes can be the first step toward better health.

Understanding Treatment And Management

The good thing here is that thyroid-related conditions are easily manageable after proper diagnosis. Treatment for hypothyroidism entails administering medications that help normalize hormonal levels in the body. Such therapy helps in balancing metabolic processes naturally.

Along with medical treatment, lifestyle measures remain important. Maintaining a balanced diet, regular physical activity, adequate sleep, and stress management can support overall metabolic health and help improve quality of life. However, people should avoid self-medicating with supplements or relying on unverified remedies claiming to “boost” thyroid function.

As awareness around metabolic health grows, World Thyroid Day is an opportunity to move beyond assumptions. Understanding the connection between thyroid function and metabolism can help people recognize symptoms early and seek timely care. Sometimes, the body may be signaling that there is more to the story than lifestyle alone.