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A carnivore diet is a restrictive diet that only includes meat, fish, and other animal products like dairy and eggs. More recently, it has been brought into the limelight by influencers and social media personalities. In fact, there is a whole community of "meatfluencer" who are sharing their meat-eating plans. One of them is Dr Paul Saladino MD, whose belief that there was no better way to prevent chronic diseases than a carnivore diet prompted him to write books and post videos regarding the same. He believed so much in this eating plan that he became a go-to person for many following the same plan, until recently, when he decided to quit.
Carnivore Diet Disrupted His Sleep
Switching to an all-meat diet isn't always straightforward, especially when it comes to digestion—a lesson Dr Saladino learned firsthand. He experienced sleep disturbances, likely due to the difficulty of digesting high-protein meals. Since protein takes longer to break down, it demands more energy from the body, which can interfere with rest.
According to Johns Hopkins Medicine, digestion slows by up to 50% during sleep. Additionally, many types of meat contain tyramine, a compound derived from the amino acid tyrosine. Increased tyramine intake can lead to health issues and also triggers the release of norepinephrine, a hormone that raises heart rate and blood pressure, making restful sleep harder to achieve.
He also experienced hypnagogic jerks—sudden muscle spasms that jolt the body awake. "I would fall asleep but then jerk myself awake like I was falling multiple times. It was stressful and traumatic, leading to poor sleep," he shared in his YouTube video.
Eating Only Meat May Have Triggered Heart Palpitations
Another concerning side effect Dr Saladino experienced was heart palpitations—episodes where his heart felt like it was racing or fluttering. While stress is a common cause, few would immediately link palpitations to meat consumption.
However, a sudden shift to an all-meat diet can lead to electrolyte imbalances. The elimination of carbohydrates lowers insulin levels, prompting the kidneys to excrete more sodium. This disrupts the balance of essential minerals like potassium and magnesium, which are crucial for heart function.
Muscle Cramps Became Persistent
Dr Saladino also suffered from frequent muscle cramps while following the carnivore diet. In a post on X, he emphasized the importance of maintaining adequate magnesium, calcium, and potassium levels to prevent cramping. He initially believed that animal-based foods provided sufficient minerals, but his ongoing cramps led him to reconsider.
"I started to think maybe long-term ketosis is not great for me,” he admitted on the *More Plates More Dates* podcast. “Probably not a great thing for most humans."
His Testosterone Levels Dropped Significantly
Dr Saladino also saw a decline in his testosterone levels after following the carnivore diet for over a year. "At the beginning of my carnivore experiment, my testosterone was about 800. After a year to a year and a half, it had dropped to around 500," he revealed.
The issue likely stems from excessive protein intake, which can elevate inflammation and disrupt hormone levels. A 2022 study published in Nutrition and Health found that consuming more than 35% of daily calories from protein can lead to various negative effects, including reduced testosterone.
He Had Chronically Low Insulin Levels
Because he largely eliminated carbohydrates—except for a small amount of fruit—Dr Saladino developed persistently low blood sugar. In his YouTube video, he explained, "I had very low insulin because I wasn’t eating carbohydrates, and the protein I consumed wasn’t insulinogenic enough."
While some diabetics report improved blood sugar control on the carnivore diet, its effects vary based on individual metabolic responses. For non-diabetics, low insulin can lead to hypoglycemia, causing symptoms like dizziness, confusion, a racing heart, and, in extreme cases, seizures or coma. Mild cases can be managed with fast-acting carbohydrates like juice or candy, but severe episodes require medical attention.
His Blood Test Results Showed Concerning Imbalances
Lab tests revealed that his magnesium levels were low, while his sex hormone-binding globulin (SHBG) was elevated—both potential red flags for long-term health issues.
A magnesium deficiency can cause numbness, tingling, fatigue, nausea, headaches, and muscle cramps. Since cramps often strike at night, low magnesium may also contribute to sleep disturbances.
High SHBG levels indicate an excess of circulating protein in the blood, which can increase the risk of heart disease, osteoporosis, and depression. To counteract these imbalances, introducing more magnesium-rich foods—such as leafy greens, nuts, beans, and yogurt—could be beneficial.
He Felt Cold All The Time
Electrolyte imbalances and metabolic disruptions can even affect body temperature, which Dr. Saladino experienced firsthand. "I was always cold,"he shared in his YouTube video.
Upon testing his thyroid function, he discovered that his total T3 and free T3 hormone levels were "not ideal." These hormones regulate metabolism, and low levels can slow down metabolic processes, leading to cold intolerance.
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Kidney disease is one of those conditions where myths quietly cause a lot of damage. Misinformation about symptoms, diet, medicines, and treatment can delay diagnosis, worsen kidney health, and prevent people from taking simple steps that could protect their kidneys early on.
Myth: Kidney disease is rare.
Fact: It’s actually quite common, but many people don’t even know they have it.
Myth: You’ll feel it if something is wrong.
Fact: Early chronic kidney disease (CKD) is usually silent, and symptoms often appear only after significant damage has already occurred.
Even something as simple as a slightly raised creatinine is often ignored.
Fact: Even mild elevations can signal a meaningful loss of kidney function.
Myth: Dialysis cures kidney disease.
Fact: Dialysis does not cure kidney disease. It only replaces some kidney functions to help keep the body in balance.
Myth: If dialysis is needed in Acute Kidney Injury (AKI), it means lifelong dialysis.
Fact: Dialysis in AKI may be temporary. In advanced CKD, however, it is often long-term or lifelong unless a kidney transplant is performed.
Myth: More water is always better.
Fact: Hydration is important, but too much water isn’t helpful for everyone—especially in advanced CKD, where fluid intake may need to be restricted.
Myth: All kidney patients should eat the same diet.
Fact: Kidney diets are highly individualized. High-protein diets, often seen as healthy, can increase stress on damaged kidneys. Plant-based proteins can be a suitable alternative in many cases.
Myth: Herbal or indigenous remedies can cure or prevent kidney disease.
Fact: Many of these remedies are unregulated and may actually worsen kidney damage because of hidden toxins or heavy metals.
Myth: Painkillers are harmless.
Fact: Regular use of medicines like NSAIDs can quietly damage the kidneys over time.
At the end of the day, kidney disease isn’t just about treatment—it’s about awareness. Getting the facts right can make all the difference.
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There are many components of weather that are reported to affect migraine, such as barometric pressure, humidity, temperature, and seasons. A drop in pressure (often before a storm) can create a pressure imbalance between the environment and the sinuses/inner ear, stimulating nerves and causing headaches.
Rapid shifts in temperature or intense cold/heat can trigger migraine attacks. Both high humidity and very dry air can trigger migraine symptoms. Bright Sunlight or Intense sun exposure, especially reflecting off snow or water, is a significant trigger for migraine.
Weather changes can cause chemical imbalances in the brain, specifically affecting serotonin levels, which are involved in migraine development. They can also cause inflammation or a "pressure difference" in the sinuses.
Both spring/summer (due to heat and allergens) and winter (due to cold/dry air) can trigger migraines and sinus problems. While many studies report weather as a trigger, some studies suggest that our perception of the trigger can exceed the actual statistical impact.
Often, it is a combination of factors, such as allergies in the spring or the flu in autumn, that triggers the headache, rather than just the air pressure.
Maintaining a migraine diary for at least 90 days helps identify specific weather patterns that trigger your attacks.
Seasonal allergies do not cause migraine attacks, but migraine is commonly misdiagnosed as a sinus headache, because some symptoms can overlap. It is common for migraine to be associated with forehead and facial pressure over the sinuses, as well as a blocked or runny nose.
However, sinus issues may be accompanied by a fever rather than a migraine. Migraines can cause activation of the nerves in the face (referred to as cranial autonomic activation), which can lead to the blocked, congested feeling.
If weather changes are a trigger for you, this can be difficult to avoid, and beyond your control, but it can be useful to keep an eye on the weather forecast. A preventive treatment may be needed to reduce the overall sensitivity to such changes, allowing you more freedom to plan your daily activities. When you think the weather might increase the risk, it is useful to treat early to shorten and completely stop the migraine attack.
Attacks that are treated early will have fewer debilitating symptoms by not becoming fully developed and severe. Drink enough water to make up for extra fluid loss on warmer days and during physical activities.
Consider taking water with you when out to remain well hydrated and to compensate for excessive sweating. Consider staying indoors during the peak hours of brightness if that is an option.
If going out, be prepared by wearing protective sunglasses or a hat to minimize glare and light. Use a humidifier to maintain indoor humidity between 40-50% to prevent nasal passages from drying out, especially in winter.
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Psilocybin is the active ingredient found in magic mushrooms, and a new study shows that just one high dose (25 mg) is enough to cause alterations in the brain’s structures and help improve mental health.
The changes could explain why some people report psychological benefits from the experience, revealed the study published in the journal Nature Communications. The study found that the effect may last for up to a month after the experience.
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In the study, researchers from the University of California, San Francisco, and Imperial College London argue that the effect may lead to “subsequent improvements in mental health”.
"Psychedelic means 'psyche-revealing,' or making the psyche visible," said senior author Robin Carhart-Harris, Professor of Neurology at UCSF.
"Our data shows that such experiences of psychological insight relate to an entropic quality of brain activity and how both are involved in causing subsequent improvements in mental health. It suggests that the trip—and its correlates in the brain—is a key component of how psychedelic therapy works," Carhart-Harris added.
Psilocybin has been the subject of several studies in people that have found it appears to alleviate symptoms of depression and anxiety. It has also shown promise in addiction medicine.
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In the latest study on 28 people, none had a diagnosed mental health condition. The team gave the participants a 1 mg dose of psilocybin, which the researchers regarded as a placebo, and then monitored them with electroencephalography (EEG), which records brain activity from electrodes on the scalp.
One month after the placebo, the subjects were given 25 mg of psilocybin, a dose capable of eliciting a strong psychedelic trip.
After each experiment, the researchers measured the participants’ psychological insight, well-being, and cognitive ability. They also examined brain activity with functional MRI (fMRI) and brain connectivity with diffusion tensor imaging (DTI).
The results showed that within 60 minutes of taking the 25 mg dose of psilocybin, the EEG revealed higher entropy — which means that the brain was processing a richer body of information under the psychedelic.
A month later, the researchers looked at their subjects' brains with DTI, which measures the diffusion of water along neural tracts in the brain, and found that they were denser and had more integrity. This is the opposite of what happens in aging, which makes these tracts more diffuse.
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While the result is a never-before-seen sign of how psychedelics can change the brain, the researchers cautioned that more work needs to be done to better understand the meaning of this change.
The participants noted that they had experienced more psychological insight after taking the 25 mg of psilocybin than they had after the 1 mg placebo, and noted "feeling optimistic about the future".
A month after the study, they also did better on a test of cognitive flexibility.
"Psilocybin seems to loosen up stereotyped patterns of brain activity and give people the ability to revise entrenched patterns of thought," said Taylor Lyons, a research associate at Imperial College London and the first author of the paper. "The fact that these changes track with insight and improved well-being is especially exciting."
The findings could improve treatment for people with mental illness with psilocybin, for example, by ensuring that the right dosage is used to produce the right amount of brain entropy to promote insight.
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