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A carnivore diet is a restrictive diet that only includes meat, fish, and other animal products like dairy and eggs. More recently, it has been brought into the limelight by influencers and social media personalities. In fact, there is a whole community of "meatfluencer" who are sharing their meat-eating plans. One of them is Dr Paul Saladino MD, whose belief that there was no better way to prevent chronic diseases than a carnivore diet prompted him to write books and post videos regarding the same. He believed so much in this eating plan that he became a go-to person for many following the same plan, until recently, when he decided to quit.
Carnivore Diet Disrupted His Sleep
Switching to an all-meat diet isn't always straightforward, especially when it comes to digestion—a lesson Dr Saladino learned firsthand. He experienced sleep disturbances, likely due to the difficulty of digesting high-protein meals. Since protein takes longer to break down, it demands more energy from the body, which can interfere with rest.
According to Johns Hopkins Medicine, digestion slows by up to 50% during sleep. Additionally, many types of meat contain tyramine, a compound derived from the amino acid tyrosine. Increased tyramine intake can lead to health issues and also triggers the release of norepinephrine, a hormone that raises heart rate and blood pressure, making restful sleep harder to achieve.
He also experienced hypnagogic jerks—sudden muscle spasms that jolt the body awake. "I would fall asleep but then jerk myself awake like I was falling multiple times. It was stressful and traumatic, leading to poor sleep," he shared in his YouTube video.
Eating Only Meat May Have Triggered Heart Palpitations
Another concerning side effect Dr Saladino experienced was heart palpitations—episodes where his heart felt like it was racing or fluttering. While stress is a common cause, few would immediately link palpitations to meat consumption.
However, a sudden shift to an all-meat diet can lead to electrolyte imbalances. The elimination of carbohydrates lowers insulin levels, prompting the kidneys to excrete more sodium. This disrupts the balance of essential minerals like potassium and magnesium, which are crucial for heart function.
Muscle Cramps Became Persistent
Dr Saladino also suffered from frequent muscle cramps while following the carnivore diet. In a post on X, he emphasized the importance of maintaining adequate magnesium, calcium, and potassium levels to prevent cramping. He initially believed that animal-based foods provided sufficient minerals, but his ongoing cramps led him to reconsider.
"I started to think maybe long-term ketosis is not great for me,” he admitted on the *More Plates More Dates* podcast. “Probably not a great thing for most humans."
His Testosterone Levels Dropped Significantly
Dr Saladino also saw a decline in his testosterone levels after following the carnivore diet for over a year. "At the beginning of my carnivore experiment, my testosterone was about 800. After a year to a year and a half, it had dropped to around 500," he revealed.
The issue likely stems from excessive protein intake, which can elevate inflammation and disrupt hormone levels. A 2022 study published in Nutrition and Health found that consuming more than 35% of daily calories from protein can lead to various negative effects, including reduced testosterone.
He Had Chronically Low Insulin Levels
Because he largely eliminated carbohydrates—except for a small amount of fruit—Dr Saladino developed persistently low blood sugar. In his YouTube video, he explained, "I had very low insulin because I wasn’t eating carbohydrates, and the protein I consumed wasn’t insulinogenic enough."
While some diabetics report improved blood sugar control on the carnivore diet, its effects vary based on individual metabolic responses. For non-diabetics, low insulin can lead to hypoglycemia, causing symptoms like dizziness, confusion, a racing heart, and, in extreme cases, seizures or coma. Mild cases can be managed with fast-acting carbohydrates like juice or candy, but severe episodes require medical attention.
His Blood Test Results Showed Concerning Imbalances
Lab tests revealed that his magnesium levels were low, while his sex hormone-binding globulin (SHBG) was elevated—both potential red flags for long-term health issues.
A magnesium deficiency can cause numbness, tingling, fatigue, nausea, headaches, and muscle cramps. Since cramps often strike at night, low magnesium may also contribute to sleep disturbances.
High SHBG levels indicate an excess of circulating protein in the blood, which can increase the risk of heart disease, osteoporosis, and depression. To counteract these imbalances, introducing more magnesium-rich foods—such as leafy greens, nuts, beans, and yogurt—could be beneficial.
He Felt Cold All The Time
Electrolyte imbalances and metabolic disruptions can even affect body temperature, which Dr. Saladino experienced firsthand. "I was always cold,"he shared in his YouTube video.
Upon testing his thyroid function, he discovered that his total T3 and free T3 hormone levels were "not ideal." These hormones regulate metabolism, and low levels can slow down metabolic processes, leading to cold intolerance.
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After surgery, radiotherapy could significantly decrease the chances of an atypical meningioma returning, according to a new international phase 3 trial published in The Lancet.
The findings come from the ROAM/EORTC-1308 trial, the first randomised controlled trial to directly test whether patients with a completely removed atypical meningioma benefit from receiving radiotherapy or whether regular scans and observation are enough.
The results could help settle a treatment question that has remained uncertain for years.
Meningiomas are the most common brain tumours in adults. They develop from the meninges, the protective membranes surrounding the brain, and spinal cord.
An atypical meningioma is classified as a WHO grade 2 tumour. Unlike grade 1 meningiomas, that generally grow slowly, grade 2 tumours are more likely to grow again after surgery.
Even when surgeons manage to remove the entire visible tumour, microscopic tumour cells may remain, sparking a risk of recurrence.
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The ROAM/EORTC-1308 trial enrolled 157 patients whose atypical meningiomas had been completely removed surgically. They were randomly assigned to either:
After a median follow-up of about five years, the difference in recurrence was significant. 14% of patients in the radiotherapy group experienced a recurrence, compared to 30% in the observation group. In other words, the risk of recurrence was reduced by nearly half with postoperative radiotherapy.
Additionally, at five years, about 80% of patients receiving radiotherapy remained free of recurrence, compared to about 64% of those who were monitored without immediate radiotherapy.
Also read: After 70% of His Tongue Was Removed For Cancer, Lawyer Regains Speech & Returns To Court
Until now, doctors have had to weigh two approaches after complete surgical removal of an atypical meningioma.
One option is to give radiotherapy immediately, hoping to destroy microscopic tumour cells that surgery may have missed. The other is to monitor the patient with regular brain scans and use radiotherapy if the tumour returns.
The uncertainty existed as strong randomised evidence showing whether immediate radiotherapy actually reduced recurrence had been lacking. The trial helps cement that evidence.
The researchers say that treatment decisions still need to be made jointly by doctors and patients, taking into account possible side effects and the long-term consequences of radiation treatment. Serious radiation-related complications were uncommon in the trial.
The study also did not establish whether the recurrence benefit extends beyond five years. This means that longer follow-up will be needed to gather more evidence. According to the researchers, the findings are expected to shape national and international treatment guidelines.
The options may extend for patients who have undergone complete removal of a WHO grade 2 atypical meningioma. Rather than contemplating “Should we simply watch and wait?”, they can consider moving to a more evidence-based discussion about whether postoperative radiotherapy should be offered upfront.
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Heart care has been revolutionized in recent decades. New imaging tools, less invasive procedures, implantable devices and digital instruments are allowing doctors to find problems earlier and with more detail. This means that treatment options tend to be more personalized and recovery time can be shortened.
A big part of this shift comes from new tech in heart testing. Doctors can see how big the heart is, what shape it is and how it moves using cardiac CT, MRI and echo. These tests can give specific information on the functioning of the heart. AI is also being looked at for tasks like reading ECG results, analysing heart scans, and tracking patients over time. The American Heart Association says AI may have uses across heart care. At the same time, many tools still need more proof in real clinical settings before they are widely used.
Also read: Don’t Miss a Beat: Why Every Newborn Deserves a Heart Check
Tech is also changing how some heart issues are handled. In the past, some cases needed full open surgery. Now, for certain patients, doctors may use catheter-based or minimally invasive methods instead. Take TAVR as an example. In that approach, a new aortic valve is placed using a catheter. It is positioned inside the older, damaged valve. For the right group of patients, this can avoid open surgery.
Device design is moving forward too. Newer cardiac devices are adding options for people with rhythm problems and other heart conditions. Leadless pacemakers are one example. These devices are meant to support heart rhythm in an effective way while reducing some drawbacks seen with older device types.
Remote monitoring and wearable tools are growing fast. Some devices can track things like heart rate all day. That can reveal issues that someone might not notice on their own. Still, these tools should sit alongside routine checkups. They should not be used to diagnose yourself.
At the end of the day, the goal is not to swap out a cardiologist for a machine. Tech should help doctors gather clearer data. It can also support more accurate procedures. It may even spot disease earlier than before. What treatment makes sense varies from person to person. Doctors weigh age, past health, how bad the condition is, the test results, and the overall level of risk. As new heart devices keep coming, doctors will need solid proof and good judgment about who should use them. That is how new ideas lead to real gains in heart care.
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She came to the hospital because of a cough that would not go away. The cough was eventually found to be nothing serious. But her CT scan revealed something unexpected — a 12 mm nodule in the outer part of her right lung.
She had never smoked. She felt completely well.
Yet that tiny shadow raised a big question: was it an old tuberculosis scar, a harmless growth, or an early lung cancer?
A CT scan can show us that a nodule is there. It cannot always tell us what it is.
This is an increasingly familiar situation. As CT scans have become more widely used, particularly after the COVID-19 pandemic, doctors are finding small lung nodules in people being scanned for entirely different reasons. Most turn out to be benign. Some, however, need closer assessment.
India has another challenge. Tuberculosis and its scars are common, and a lung shadow can sometimes be attributed to TB without tissue confirmation. While treating tuberculosis promptly is important, assuming that every suspicious nodule is TB can occasionally delay the diagnosis of something else, including cancer.
The answer, when appropriate, is to obtain a tissue sample.
Traditionally, a small nodule deep in the lung could be difficult to reach. A needle biopsy through the chest can be effective but carries a risk of a collapsed lung. Conventional bronchoscopy is excellent for the larger airways but becomes more challenging as the target gets smaller and farther towards the edge of the lung. Surgery may sometimes be necessary.
Navigation bronchoscopy uses the patient's CT scan to create a three-dimensional map of the airways and guide a thin catheter towards the nodule. Cone Beam CT adds real-time three-dimensional imaging during the procedure, allowing the doctor to check where the instruments are in relation to the lesion before taking the biopsy.
In simple terms, navigation helps us find the way; Cone Beam CT helps us confirm we are there.
The tissue can then be examined immediately where appropriate, helping determine whether the sample is adequate and whether additional material is needed for advanced testing.
Importantly, not every nodule needs a biopsy. Many are best managed through carefully planned follow-up scans. The decision depends on the nodule's size and appearance, previous scans, and the patient's overall risk.
For patients, the message is reassuring: a lung nodule does not mean cancer. But it should not be ignored either.
Keep previous scans. Ask what the likely possibilities are. Understand why your doctor recommends surveillance or biopsy — and make sure the follow-up happens.
Today, advanced bronchoscopy is helping doctors turn a worrying shadow into something much more useful: an answer.
(By Dr Shyam Krishnan, Intervention Pulmonologist, CMRI)
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