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A carnivore diet is a restrictive diet that only includes meat, fish, and other animal products like dairy and eggs. More recently, it has been brought into the limelight by influencers and social media personalities. In fact, there is a whole community of "meatfluencer" who are sharing their meat-eating plans. One of them is Dr Paul Saladino MD, whose belief that there was no better way to prevent chronic diseases than a carnivore diet prompted him to write books and post videos regarding the same. He believed so much in this eating plan that he became a go-to person for many following the same plan, until recently, when he decided to quit.
Carnivore Diet Disrupted His Sleep
Switching to an all-meat diet isn't always straightforward, especially when it comes to digestion—a lesson Dr Saladino learned firsthand. He experienced sleep disturbances, likely due to the difficulty of digesting high-protein meals. Since protein takes longer to break down, it demands more energy from the body, which can interfere with rest.
According to Johns Hopkins Medicine, digestion slows by up to 50% during sleep. Additionally, many types of meat contain tyramine, a compound derived from the amino acid tyrosine. Increased tyramine intake can lead to health issues and also triggers the release of norepinephrine, a hormone that raises heart rate and blood pressure, making restful sleep harder to achieve.
He also experienced hypnagogic jerks—sudden muscle spasms that jolt the body awake. "I would fall asleep but then jerk myself awake like I was falling multiple times. It was stressful and traumatic, leading to poor sleep," he shared in his YouTube video.
Eating Only Meat May Have Triggered Heart Palpitations
Another concerning side effect Dr Saladino experienced was heart palpitations—episodes where his heart felt like it was racing or fluttering. While stress is a common cause, few would immediately link palpitations to meat consumption.
However, a sudden shift to an all-meat diet can lead to electrolyte imbalances. The elimination of carbohydrates lowers insulin levels, prompting the kidneys to excrete more sodium. This disrupts the balance of essential minerals like potassium and magnesium, which are crucial for heart function.
Muscle Cramps Became Persistent
Dr Saladino also suffered from frequent muscle cramps while following the carnivore diet. In a post on X, he emphasized the importance of maintaining adequate magnesium, calcium, and potassium levels to prevent cramping. He initially believed that animal-based foods provided sufficient minerals, but his ongoing cramps led him to reconsider.
"I started to think maybe long-term ketosis is not great for me,” he admitted on the *More Plates More Dates* podcast. “Probably not a great thing for most humans."
His Testosterone Levels Dropped Significantly
Dr Saladino also saw a decline in his testosterone levels after following the carnivore diet for over a year. "At the beginning of my carnivore experiment, my testosterone was about 800. After a year to a year and a half, it had dropped to around 500," he revealed.
The issue likely stems from excessive protein intake, which can elevate inflammation and disrupt hormone levels. A 2022 study published in Nutrition and Health found that consuming more than 35% of daily calories from protein can lead to various negative effects, including reduced testosterone.
He Had Chronically Low Insulin Levels
Because he largely eliminated carbohydrates—except for a small amount of fruit—Dr Saladino developed persistently low blood sugar. In his YouTube video, he explained, "I had very low insulin because I wasn’t eating carbohydrates, and the protein I consumed wasn’t insulinogenic enough."
While some diabetics report improved blood sugar control on the carnivore diet, its effects vary based on individual metabolic responses. For non-diabetics, low insulin can lead to hypoglycemia, causing symptoms like dizziness, confusion, a racing heart, and, in extreme cases, seizures or coma. Mild cases can be managed with fast-acting carbohydrates like juice or candy, but severe episodes require medical attention.
His Blood Test Results Showed Concerning Imbalances
Lab tests revealed that his magnesium levels were low, while his sex hormone-binding globulin (SHBG) was elevated—both potential red flags for long-term health issues.
A magnesium deficiency can cause numbness, tingling, fatigue, nausea, headaches, and muscle cramps. Since cramps often strike at night, low magnesium may also contribute to sleep disturbances.
High SHBG levels indicate an excess of circulating protein in the blood, which can increase the risk of heart disease, osteoporosis, and depression. To counteract these imbalances, introducing more magnesium-rich foods—such as leafy greens, nuts, beans, and yogurt—could be beneficial.
He Felt Cold All The Time
Electrolyte imbalances and metabolic disruptions can even affect body temperature, which Dr. Saladino experienced firsthand. "I was always cold,"he shared in his YouTube video.
Upon testing his thyroid function, he discovered that his total T3 and free T3 hormone levels were "not ideal." These hormones regulate metabolism, and low levels can slow down metabolic processes, leading to cold intolerance.
Blockbuster GLP-1 drugs, with semaglutide as the key ingredient, have shown promise in treating conditions ranging from diabetes and obesity to certain cancers.
Now, US researchers are set to test whether semaglutide can also help treat alcohol use disorder (AUD), particularly among veterans. AUD affects an estimated 400 million people worldwide, or about 7% of people aged 15 years and older.
The US Department of Veterans Affairs (VA) has announced a new clinical trial to evaluate the effectiveness of semaglutide in treating AUD and is aimed directly at benefiting Veterans.
"By exploring emerging treatment options like the use of a GLP-1 for AUD, we aim to expand the tools available to help Veterans take control of their health and recovery," said VA Secretary Doug Collins.
Currently, more than 400,000 US veterans have been diagnosed with AUD, while an estimated 11% of US adults are affected by the condition.
Also read: GLP-1 Weight-Loss Drugs Show Promise for 17 Million With Binge Eating Disorder, Suggests Study
The study, called the Cessation or Reduction of Alcohol Consumption in Veterans (CRACV) trial, will enroll more than 600 veterans across 18 VA medical centers in the US.
Participants aged 18 to 80 with moderate or severe AUD will receive weekly injections of either semaglutide or a placebo for 24 weeks, followed by a safety follow-up period.
Researchers will assess changes in alcohol consumption, overall health, and quality of life to determine whether semaglutide could become a new treatment option for alcohol use disorder.
Evidence is also emerging that GLP-1 medications may influence alcohol consumption. A Phase 2 clinical trial published in the American Journal of Psychiatry in July suggests that oral semaglutide may help reduce heavy and harmful drinking, even among people who are not trying to quit alcohol completely.
The trial included 50 adults with moderate to severe alcohol use disorder who wanted to reduce or stop drinking. Participants were randomly assigned to receive either daily oral semaglutide or a placebo for eight weeks.
The semaglutide dose increased from 3 mg per day during the first four weeks to 7 mg per day during the remaining four weeks.
While semaglutide did not significantly reduce laboratory-assessed craving or the average number of drinks per day compared with placebo, it significantly reduced heavy drinking days.
Compared with participants receiving placebo, those taking semaglutide had fewer heavy drinking days during the final four weeks of treatment. They also consumed fewer drinks on drinking days and reported greater reductions in everyday alcohol cravings and alcohol-related negative consequences.
"It could represent a new treatment option for alcohol use disorder, particularly for those who have not benefited from existing medications, and may reduce alcohol-related health and social harms. Importantly, even reducing heavy drinking can lead to meaningful improvements for patients and families," said Joseph Schacht, PhD, professor of psychiatry at the University of Colorado Anschutz School of Medicine.
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As many as 23 cases of young women aged below 35 suffering from heart-related problems in only a month (reported by the Indian Medical Association) have left cardiologists concerned. What were earlier considered symptoms of stress, anxiety, and hormonal imbalances such as chest pain, breathing difficulty, palpitations, unexplained fatigue, and giddiness are now not being taken lightly when they occur for a prolonged time or recur. They are being increasingly identified as cardiac-related problems even in young adults.
Lack of physical activity, improper diet, obesity, diabetes, high blood pressure, smoking, and continuous stress have been labeled responsible for these problems. Some women's conditions like PCOD and autoimmune diseases can also put them at a higher cardiovascular risk. Regular check-ups, monitoring of blood pressure, blood sugar, cholesterol levels, and timely check-ups for the heart whenever these conditions occur can help in detecting the problems at the earliest, thus initiating treatment and recovery effectively.
In today's times, management of complicated heart diseases in India has dramatically improved and achieved outcomes at par with global standards. Today, the management of very severe heart valve disease offers much in terms of percutaneous catheter-based solutions, which, alongside conventional surgery (performed according to a person's age, general health, and clinical profile), give improved outcomes. Early detection and management of heart diseases prevent major complications and restore an individual's quality of life.
Increased knowledge about heart health, early identification of symptoms, and immediate medical attention are very important to achieve successful results. The observance of preventive measures such as engaging in regular exercise, a healthy diet, sleep, managing stress, and conducting regular medical checkups helps in the prevention of heart problems. Early diagnosis and adequate treatment form the key factors for achieving the best heart health.
By Dr. Nagendra Singh Chouhan, Interventional Cardiologist at Medanta Hospitals, Gurugram
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Feeling breathless after climbing several flights of stairs or a session of strenuous exercise is usually considered normal.
But breathlessness that appears suddenly, happens frequently, or occurs during routine activities should never be dismissed as tiredness or lack of fitness.
Breathlessness, clinically known as dyspnoea, can occur due to many reasons. Asthma, allergies, respiratory infections, chronic lung disease, and heart problems are some of the common possibilities. Anxiety, anaemia and obesity could also be driving factors.
In some cases, persistent or unexplained breathing difficulty may also be linked to more serious conditions, including lung cancer. The important thing is to understand when breathlessness needs medical attention.
HealthandMe spoke to lung disease experts - Dr. Sachin Kumar, Director of Pulmonology & Critical Care Medicine, Sakra World Hospital, Bengaluru, Dr. Sanjeev Kumar, Director & Unit Head of GI & HPB Surgical Oncology & Clinical Administrator, Surgical Oncology, Max Super Specialty Hospital, Dwarka, Dr. Ruchi Singh, HOD & Senior Consultant, Radiation Oncology, Asian Institute of Medical Sciences, and Dr. Ashwin Mallya, Uro-Oncologist and Robotic Surgeon, Sir Ganga Ram Hospital.
Dr. Sanjeev Kumar explains that breathlessness that gets worse during routine activities are major red flags. He also says that other symptoms like chronic cough, coughing up blood, tiredness, and others should not be neglected.
He says, "Pay attention if breathlessness is accompanied by chest pain or pressure, dizziness, fainting, unusual sweating, bluish lips or fingertips, or a feeling that you cannot get enough air. A persistent cough, wheezing, recurring chest infections, coughing up blood, unexplained weight loss or prolonged fatigue along with breathlessness also deserves medical assessment. A cough that does not go away or changes in a long-standing smoker’s cough should not be overlooked. Although these symptoms can have several causes, they can occasionally be associated with lung cancer and need appropriate evaluation."
He also said that changes in usual breathing capacity is also a red flag. He said that if you previously walked comfortably for 20–30 minutes but now have to stop frequently because you are breathless, this change should not simply be attributed to age.
Also read: Lung Nodule on CT Scan? Doctors Explain When You Should Worry
Dr. Ruchi Singh points to a worrying trend. She said that the initial symptoms of lung cancer are usually dismissed as routine, which leads to delayed evaluation and treatment.
She says, "One of the most concerning things we are tracking is how late many patients present. Because symptoms like persistent cough or breathlessness are so easily mistaken for pollution-related irritation or a lingering infection, people delay getting scanned."
She explains that earlier detection through low-dose CT screening in high-risk groups remains the best tool for improving survival, and awareness needs to catch up with how the patient's profile itself is changing.
Also read: Can Fitness Hide Lung Cancer? Why Even Active People Shouldn't Ignore Symptoms
Talking about how lung cancer could metastasize, Dr Ashwin Mallya explains that along with early evaluation, it is essential to adopt a treatment strategy
Dr Mallya said, "Although primarily a thoracic malignancy, lung cancer frequently extends beyond the chest. Adrenal metastases are among its most common distant manifestations, while renal metastases, though less frequent, are well recognised."
He added, "These patterns underscore the importance of a multidisciplinary approach, often bringing urologists into the care of patients with advanced disease."
Also read: 'I Wish Every Patient Knew This Before Their Lung Cancer Diagnosis'- Lessons From An Oncologist
Giving a real-life example of how lung cancer is no longer a smoker's disease, Dr Sachin Kumar said, "A 50-year-old lady went to the clinic seeking a second opinion after being treated for "asthma" for several weeks. She complained of occasional breathlessness and a persistent cough. Despite inhalers, her symptoms continued. A simple chest X-ray revealed something entirely different: a massive pleural effusion (fluid around the lung). Further evaluation confirmed the underlying cause: *lung cancer that had spread to the pleura (the lining surrounding the lungs).
He added, "This case is a reminder that not every cough or episode of breathlessness is asthma. When symptoms persist or do not respond as expected, they deserve a fresh look. Sadly, lung cancer is no longer a disease seen only in older male smokers. In our own practice, we now diagnose around 2–3 new cases of primary lung cancer every three months, and nearly 40% of these patients are either women or people who have never smoked."
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