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A carnivore diet is a restrictive diet that only includes meat, fish, and other animal products like dairy and eggs. More recently, it has been brought into the limelight by influencers and social media personalities. In fact, there is a whole community of "meatfluencer" who are sharing their meat-eating plans. One of them is Dr Paul Saladino MD, whose belief that there was no better way to prevent chronic diseases than a carnivore diet prompted him to write books and post videos regarding the same. He believed so much in this eating plan that he became a go-to person for many following the same plan, until recently, when he decided to quit.
Carnivore Diet Disrupted His Sleep
Switching to an all-meat diet isn't always straightforward, especially when it comes to digestion—a lesson Dr Saladino learned firsthand. He experienced sleep disturbances, likely due to the difficulty of digesting high-protein meals. Since protein takes longer to break down, it demands more energy from the body, which can interfere with rest.
According to Johns Hopkins Medicine, digestion slows by up to 50% during sleep. Additionally, many types of meat contain tyramine, a compound derived from the amino acid tyrosine. Increased tyramine intake can lead to health issues and also triggers the release of norepinephrine, a hormone that raises heart rate and blood pressure, making restful sleep harder to achieve.
He also experienced hypnagogic jerks—sudden muscle spasms that jolt the body awake. "I would fall asleep but then jerk myself awake like I was falling multiple times. It was stressful and traumatic, leading to poor sleep," he shared in his YouTube video.
Eating Only Meat May Have Triggered Heart Palpitations
Another concerning side effect Dr Saladino experienced was heart palpitations—episodes where his heart felt like it was racing or fluttering. While stress is a common cause, few would immediately link palpitations to meat consumption.
However, a sudden shift to an all-meat diet can lead to electrolyte imbalances. The elimination of carbohydrates lowers insulin levels, prompting the kidneys to excrete more sodium. This disrupts the balance of essential minerals like potassium and magnesium, which are crucial for heart function.
Muscle Cramps Became Persistent
Dr Saladino also suffered from frequent muscle cramps while following the carnivore diet. In a post on X, he emphasized the importance of maintaining adequate magnesium, calcium, and potassium levels to prevent cramping. He initially believed that animal-based foods provided sufficient minerals, but his ongoing cramps led him to reconsider.
"I started to think maybe long-term ketosis is not great for me,” he admitted on the *More Plates More Dates* podcast. “Probably not a great thing for most humans."
His Testosterone Levels Dropped Significantly
Dr Saladino also saw a decline in his testosterone levels after following the carnivore diet for over a year. "At the beginning of my carnivore experiment, my testosterone was about 800. After a year to a year and a half, it had dropped to around 500," he revealed.
The issue likely stems from excessive protein intake, which can elevate inflammation and disrupt hormone levels. A 2022 study published in Nutrition and Health found that consuming more than 35% of daily calories from protein can lead to various negative effects, including reduced testosterone.
He Had Chronically Low Insulin Levels
Because he largely eliminated carbohydrates—except for a small amount of fruit—Dr Saladino developed persistently low blood sugar. In his YouTube video, he explained, "I had very low insulin because I wasn’t eating carbohydrates, and the protein I consumed wasn’t insulinogenic enough."
While some diabetics report improved blood sugar control on the carnivore diet, its effects vary based on individual metabolic responses. For non-diabetics, low insulin can lead to hypoglycemia, causing symptoms like dizziness, confusion, a racing heart, and, in extreme cases, seizures or coma. Mild cases can be managed with fast-acting carbohydrates like juice or candy, but severe episodes require medical attention.
His Blood Test Results Showed Concerning Imbalances
Lab tests revealed that his magnesium levels were low, while his sex hormone-binding globulin (SHBG) was elevated—both potential red flags for long-term health issues.
A magnesium deficiency can cause numbness, tingling, fatigue, nausea, headaches, and muscle cramps. Since cramps often strike at night, low magnesium may also contribute to sleep disturbances.
High SHBG levels indicate an excess of circulating protein in the blood, which can increase the risk of heart disease, osteoporosis, and depression. To counteract these imbalances, introducing more magnesium-rich foods—such as leafy greens, nuts, beans, and yogurt—could be beneficial.
He Felt Cold All The Time
Electrolyte imbalances and metabolic disruptions can even affect body temperature, which Dr. Saladino experienced firsthand. "I was always cold,"he shared in his YouTube video.
Upon testing his thyroid function, he discovered that his total T3 and free T3 hormone levels were "not ideal." These hormones regulate metabolism, and low levels can slow down metabolic processes, leading to cold intolerance.
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Doctors at a Mumbai hospital successfully performed a complex coronary angioplasty on an elderly diabetic patient with severely calcified coronary arteries using an advanced technique called Intravascular Lithotripsy (IVL), helping restore blood flow to the heart despite multiple procedural challenges.
The patient, who had been experiencing symptoms suggestive of coronary artery disease, was found to have extensive calcium deposits in the coronary arteries. Further evaluation also revealed poor blood flow in the leg arteries, making conventional vascular access for the procedure difficult.
Coronary artery calcification is commonly seen in elderly individuals and people with long-standing diabetes. Excessive calcium makes the arteries rigid and narrow, often making routine angioplasty technically challenging and increasing the risk of incomplete stent expansion, which can affect long-term outcomes
Severely calcified coronary arteries remain one of the biggest challenges in interventional cardiology. The calcium makes the arteries extremely rigid, making it difficult to properly expand the stent. In such situations, conventional angioplasty alone may not be sufficient.
Despite the patient’s complex anatomy and poor peripheral vascular access, the team successfully performed the procedure through the radial artery in the wrist, avoiding access through the diseased leg vessels.
Also read: Stopping Ozempic, Wegovy, Mounjaro Linked To 22% Higher Heart Attack, Stroke Risk: Study
To prepare the artery for stenting, doctors used Intravascular Lithotripsy (IVL), an advanced technology that delivers controlled sonic pressure waves to fracture deep calcium deposits within the artery wall. This allows the blood vessel to expand more effectively, enabling safe and optimal placement of the coronary stent.
IVL works on a principle similar to the technology used for breaking kidney stones, but it is specifically designed for heavily calcified coronary arteries. By modifying the calcium before placing the stent, we can achieve better stent expansion, reduce procedural complications and improve long-term outcomes in appropriately selected patients.
The procedure was completed successfully, with excellent blood flow restored to the affected coronary artery. The patient recovered well and was discharged in a stable condition.
Doctors say the case highlights how newer technologies are expanding treatment options for patients who were once considered extremely difficult to treat due to severe coronary calcification.
Advanced techniques such as IVL are transforming the management of complex coronary artery disease, particularly in elderly diabetic patients, allowing us to safely treat lesions that would have been significantly more challenging with conventional techniques alone.
The case underscores the growing role of advanced interventional cardiology in treating complex heart disease while minimising procedural risk and improving patient outcomes.
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The biological landmarks that occur in a woman’s life include many factors and menopause is one of them. Menopause is usually identified with changes in menstrual cycle, hormone levels, hot flashes and even emotional health. Nevertheless, this stage of a woman’s life is also characterized by some other things and needs to focus on woman’s cardiovascular system.
Heart problems have long been considered as the problem that concerns mostly men. Nevertheless, today it is known that cardiovascular diseases still kill more women than anything else and take the lives of almost one-third of all women in the world.
Until menopause, estrogen gives the cardiovascular system a number of advantages. It maintains the proper state of the blood vessels and assists in cholesterol regulation and proper vascular functioning. But when the woman gets into menopause, the drop of oestrogen level can cause various internal alterations. They include the increase of LDL cholesterol level, the decrease of HDL cholesterol level, elevated blood pressure, metabolic alterations and abdominal fat accumulation.
All those alterations will increase the chance of getting cardiovascular diseases, such as coronary artery disease, stroke and heart failure. According to the American Heart Association, the women become at greater risk for cardiovascular diseases after going through the process of menopause.
Also read: Is Controlling BP Enough After a Brain Bleed? Doctors Explain How to Prevent Another Stroke
On the other hand, women may suffer from various symptoms that are associated with heart disease but differ from those in men. For instance, fatigue, breathlessness, nausea, lightheadedness, jaw pain, back pain or arm pain can sometimes go unnoticed and are misdiagnosed.
Therefore, awareness and medical consultation are vital. Health checkups, blood pressure and cholesterol monitoring, living healthy, eating healthy and individualized medical advice can greatly help in decreasing risks in the future.
Also read: Preeclampsia May End With Pregnancy. Your Heart Risk May Not
Treatment for menopause should not be restricted to treating symptoms; it should include care during the entire period of health transition.
Every woman's individual health requirements and guidance through various phases of life should be in accordance with her health needs.
Menopause should never be seen as a deteriorating process but as a turning point where women can assess the state of their health and adopt preventative measures for their healthcare.
Ahead of World Heart Day, the issue of women’s heart health should go beyond just treating heart diseases and focus on preventive measures. It is not only about asking: “how do we treat heart disease in women?” It is also about asking: “how do we detect risk factors and help each woman protect her heart during one of the most critical periods in her life?” For when women understand what is going on in their body, they get the ability to make the right decisions about their health.
By Dr. Anupama Gangwal, Senior Consultant – Obstetrics and Gynaecology, Cocoon Hospital, Jaipur
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Polycystic ovarian syndrome (PCOS), now renamed polyendocrine metabolic ovarian syndrome (PMOS), can begin during adolescence and affect metabolic health, fertility and mental health, AIIMS experts said.
Speaking at a press conference in Delhi, the experts discussed PCOS risk factors, diagnosis in teenagers and the role of lifestyle management.
Obesity and sedentary habits can increase risk, but irregular periods or polycystic-looking ovaries on ultrasound do not automatically mean PCOS. Menstrual irregularity and ovarian changes can be normal during adolescence, making accurate diagnosis important.
Irregular periods are common in the first year after menstruation begins. Dr. Rajni Sharma, Professor, Division of Pediatric Endocrinology, Department of Pediatrics, AIIMS, said: “It is normal and physiological.”
However, persistent irregularity should be evaluated.
“But if they are irregular even after one year, like their duration is coming in between, duration more than 45 days up to 3 years, or after menarche, after 3 years up to 35 days cycle, or less than 21 days cycle, or less than 8 times per year cycles, or their gap is more than 3 months, then we should think that they are irregular and they should be investigated,” she said.
Also read: Why Rebranding PCOS As PMOS Could Mark A New Era In Women’s Health
Ultrasound is not routinely used to diagnose PCOS in adolescents because polycystic-looking ovaries can be normal during this stage, Dr. Rajni said.
Dr. Renu Sharma, Child Psychologist, Department of Psychiatry, AIIMS, said such findings can also cause unnecessary anxiety.
“Many times, many families come out of fear because there is a polycystic appearance in an ultrasound.”
Some girls may have PCOS-like features without meeting the diagnostic criteria and may instead be considered at risk.
“We call it at risk of PCOS. At this stage, it is best to focus on diet and lifestyle.”
Family history, obesity, type 2 diabetes and lifestyle factors can increase PCOS risk, Dr. Rajni said.
“Especially if there is type 2 diabetes, obesity, all these things are there, or mother, or her aunt had PCOS, then the risk increases.”
Poor diet and physical inactivity can also contribute.
“They are not eating fiber, fruits, vegetables. And they are consuming more junk food. And, one is, sedentary activity,” she said.
However, PCOS can also occur in girls with normal weight. “Many normal girls can also have it. Normal weight girls.”
Facial and body hair can affect self-image and self-esteem in adolescent girls with PCOS, Dr. Renu said.
“These young adolescent girls suffering from PCOS have very significant psychosocial issues," said the expert, adding that anxiety and depression are very common.
They also develop some eating disorders such as anorexia or bulimia, she said, noting that the adolescent's "self-perception, or self-concept, starts becoming negative.”
Lifestyle management is an important part of managing PCOS risk and symptoms. Dr. Vandana recommended healthier food choices and regular physical activity.
“You can make a lot of things at home, with good healthy ingredients.”
“Second, in general, you should eat more salads. You should eat more colorful fruits and vegetables, so we talk about this.”
She also stressed the importance of avoiding a sedentary lifestyle, and stressed the need for "one hour of physical activity of moderate to vigorous level daily".
“This means that, while doing that activity, you are not able to talk normally. If you can talk normally, then it means that the activity is not of moderate to vigorous level.”
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