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A carnivore diet is a restrictive diet that only includes meat, fish, and other animal products like dairy and eggs. More recently, it has been brought into the limelight by influencers and social media personalities. In fact, there is a whole community of "meatfluencer" who are sharing their meat-eating plans. One of them is Dr Paul Saladino MD, whose belief that there was no better way to prevent chronic diseases than a carnivore diet prompted him to write books and post videos regarding the same. He believed so much in this eating plan that he became a go-to person for many following the same plan, until recently, when he decided to quit.
Carnivore Diet Disrupted His Sleep
Switching to an all-meat diet isn't always straightforward, especially when it comes to digestion—a lesson Dr Saladino learned firsthand. He experienced sleep disturbances, likely due to the difficulty of digesting high-protein meals. Since protein takes longer to break down, it demands more energy from the body, which can interfere with rest.
According to Johns Hopkins Medicine, digestion slows by up to 50% during sleep. Additionally, many types of meat contain tyramine, a compound derived from the amino acid tyrosine. Increased tyramine intake can lead to health issues and also triggers the release of norepinephrine, a hormone that raises heart rate and blood pressure, making restful sleep harder to achieve.
He also experienced hypnagogic jerks—sudden muscle spasms that jolt the body awake. "I would fall asleep but then jerk myself awake like I was falling multiple times. It was stressful and traumatic, leading to poor sleep," he shared in his YouTube video.
Eating Only Meat May Have Triggered Heart Palpitations
Another concerning side effect Dr Saladino experienced was heart palpitations—episodes where his heart felt like it was racing or fluttering. While stress is a common cause, few would immediately link palpitations to meat consumption.
However, a sudden shift to an all-meat diet can lead to electrolyte imbalances. The elimination of carbohydrates lowers insulin levels, prompting the kidneys to excrete more sodium. This disrupts the balance of essential minerals like potassium and magnesium, which are crucial for heart function.
Muscle Cramps Became Persistent
Dr Saladino also suffered from frequent muscle cramps while following the carnivore diet. In a post on X, he emphasized the importance of maintaining adequate magnesium, calcium, and potassium levels to prevent cramping. He initially believed that animal-based foods provided sufficient minerals, but his ongoing cramps led him to reconsider.
"I started to think maybe long-term ketosis is not great for me,” he admitted on the *More Plates More Dates* podcast. “Probably not a great thing for most humans."
His Testosterone Levels Dropped Significantly
Dr Saladino also saw a decline in his testosterone levels after following the carnivore diet for over a year. "At the beginning of my carnivore experiment, my testosterone was about 800. After a year to a year and a half, it had dropped to around 500," he revealed.
The issue likely stems from excessive protein intake, which can elevate inflammation and disrupt hormone levels. A 2022 study published in Nutrition and Health found that consuming more than 35% of daily calories from protein can lead to various negative effects, including reduced testosterone.
He Had Chronically Low Insulin Levels
Because he largely eliminated carbohydrates—except for a small amount of fruit—Dr Saladino developed persistently low blood sugar. In his YouTube video, he explained, "I had very low insulin because I wasn’t eating carbohydrates, and the protein I consumed wasn’t insulinogenic enough."
While some diabetics report improved blood sugar control on the carnivore diet, its effects vary based on individual metabolic responses. For non-diabetics, low insulin can lead to hypoglycemia, causing symptoms like dizziness, confusion, a racing heart, and, in extreme cases, seizures or coma. Mild cases can be managed with fast-acting carbohydrates like juice or candy, but severe episodes require medical attention.
His Blood Test Results Showed Concerning Imbalances
Lab tests revealed that his magnesium levels were low, while his sex hormone-binding globulin (SHBG) was elevated—both potential red flags for long-term health issues.
A magnesium deficiency can cause numbness, tingling, fatigue, nausea, headaches, and muscle cramps. Since cramps often strike at night, low magnesium may also contribute to sleep disturbances.
High SHBG levels indicate an excess of circulating protein in the blood, which can increase the risk of heart disease, osteoporosis, and depression. To counteract these imbalances, introducing more magnesium-rich foods—such as leafy greens, nuts, beans, and yogurt—could be beneficial.
He Felt Cold All The Time
Electrolyte imbalances and metabolic disruptions can even affect body temperature, which Dr. Saladino experienced firsthand. "I was always cold,"he shared in his YouTube video.
Upon testing his thyroid function, he discovered that his total T3 and free T3 hormone levels were "not ideal." These hormones regulate metabolism, and low levels can slow down metabolic processes, leading to cold intolerance.
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People assigned female at birth live with hormone shifts throughout their lives. These chemical messengers guide nearly every system in the body. The swings linked to periods, pregnancy or menopause are easy to recognise, but many other factors can unsettle hormone levels.
The body produces more than fifty hormones through the endocrine system, and changes in any of them can signal a deeper health concern. Low insulin may point toward diabetes. Excess cortisol can influence weight gain. Other hormones, like melatonin, rise and fall through the day as part of normal rhythm. And the gradual drop in estrogen and progesterone as women approach menopause is also expected.
Puberty, pregnancy and menopause naturally reshape hormone activity. Beyond these, several conditions can disrupt normal patterns. Problems with the adrenal gland, thyroid disorders, eating disorders, congenital adrenal hyperplasia, Cushing’s syndrome, diabetes or PCOS can all change your hormone levels. Changes may also stem from stress, certain medicines, tumours, cysts or environmental chemicals.
Interest in hormones has grown recently. Earlier this month, the Food and Drug Administration agreed to remove the boxed warning on menopause hormone therapy after reviewing the evidence. The decision prompted fresh discussion among women considering treatment. Clinicians say many patients are reaching out with new questions, especially in an era filled with quick tests and supplements marketed as hormone balancers. It can be difficult to tell when testing is truly needed.
As each hormone plays a different role, symptoms vary widely. These are some of the more frequent changes seen in people, as per UCLA Health.
1. Menstrual changes: Shifts in estrogen and related hormones can alter the monthly cycle. Periods may become heavier, lighter, irregular or go missing. Stress, diet and exercise can contribute as well, but hormonal swings remain a leading cause.
2. Hair changes: Hair often reacts quickly to hormonal shifts. Pregnancy can bring thicker strands, while imbalances may trigger hair thinning or hair growth in unexpected places. Excessive facial hair may suggest elevated androgens. Hair loss can point toward a thyroid concern.
3. Skin Changes: Hormonal shifts can influence skin colour, texture and oil production. Acne may flare during pregnancy due to rising progesterone. Darkened patches of skin may appear on areas like the neck, groin or beneath the breasts when estrogen or progesterone levels change.
4. Sexual and vaginal symptoms: Lower estrogen levels, especially with age, can reduce libido and cause vaginal dryness or pain during intercourse. Some women may experience vaginal atrophy when estrogen remains low for long periods.
5. Weight changes: Sudden weight gain or weight loss can reflect a hormonal issue. Many women notice weight gain after menopause. Thyroid disorders, PCOS and Cushing’s syndrome are also linked to changes in body weight.
6. Mood and sleep difficulties: Falling estrogen levels influence serotonin, a chemical important for stable mood. Low serotonin can contribute to anxiety, irritability or low mood. These disruptions often spill into sleep. Some women also report night sweats or trouble staying asleep.
7. Digestive issues: Estrogen and progesterone affect digestion. When these hormones shift, the gut may respond with bloating, constipation or diarrhoea. Some research has linked hormonal changes in people AFAB to irritable bowel syndrome. Many notice digestive changes around their menstrual cycle.
There is no single test that measures every hormone, and at-home kits only cover a few markers. The safest first step is to speak with your primary care doctor. They can look at your overall health and decide what evaluations are appropriate.
Diagnosis may include:
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As bird flu continues to trouble several countries, health officials in the United States have reported the first known human case of the H5N5 subtype of avian influenza. The Washington State Department of Health announced on November 14, 2025, that the virus was found in a resident of Grays Harbor County.
The patient, an older adult with existing medical issues, is currently in the hospital. Authorities noted that the individual kept poultry at home that had contact with wild birds, which is believed to be the likely source of the infection, though the investigation is still underway. Since H5N5 is newly identified in humans, many are asking whether it differs from the earlier H5N1 strain.
H5N1 is a highly pathogenic form of avian influenza that mainly affects birds but can also infect mammals, including humans. It can lead to severe illness in people and has a high fatality rate, though it rarely spreads from one person to another, as per the World Health Organization. The virus has moved across continents in wild and farmed birds and has recently been found in dairy cattle and several other mammals.
The “new” H5N1 strain refers to the 2.3.4.4b clade of highly pathogenic avian influenza (HPAI), which has caused a widespread animal outbreak since appearing in 2020. This version is a newer genetic branch of H5N1 and has swept through wild birds, poultry farms and an increasing range of mammals, including dairy herds in the United States. At present, the patient infected in the U.S. has been diagnosed with the newer H5N5 subtype.
According to the CDC, both H5N5 and H5N1 fall under the avian influenza family, with the main distinction being the type of neuraminidase (N) protein on the virus surface. H5N5 contains the N5 protein, while H5N1 carries the N1 protein. Although this genetic change can influence viral features, their overall pattern of illness and symptoms is expected to be much the same, particularly in birds and livestock.
The genetic structure is the only difference, with H5N1 strain containing a subtype of influenza A with a segmented genome while the other has a new reassortant virus formed from several subtypes, possibly including H5N1, as per National Institute of Health.
Vaccines for bird flu do exist, but they are not intended for general public use and are not easily available for everyday protection. Some vaccines have been created and stored for possible deployment in people at higher risk, such as poultry workers and farm staff, and they are also used in animals like chickens to help manage outbreaks. The United States and several other countries have stockpiled H5N1-specific vaccines that could be rolled out if the threat to humans grows. A few nations, including Finland, are already offering them to certain high-risk groups. At the moment, there is no advice for the wider public to take a bird flu vaccine, as there is no sustained human-to-human spread and no mass-market human vaccine in use.
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Flu season is here again and global health experts are getting worried about a strain that came up in June. The worry's cause is that the strain came up four months after the makeup of this year's flu shot.
This is the strain H3N2. The strain has caused outbreaks in Canada and in the UK, and health officials have warned about the early wave that is sending people to the hospitals.
As per Dr Wenqing Zhang, who is the head of the World Health Organization (WHO)'s Global Respiratory Threats Unit, "Since it emerged, it is rapidly spreading and predominating in some countries so far in the Northern Hemisphere."
The version of H3N2, which has been circulated worldwide this year "acquired 7 new mutations over the summer," said Antonia Ho, a consultant in infectious disease at Scotland's University of Glasgow. As per her media statement, this "means the virus is quite different to the H3N2 strain included in this year's vaccine".
The strain is now picking up in Canada, after it has been active in the UK, leading to flu cases being triple to what it was the same time last year. Furthermore, generally, H3N2 is thought to cause more illness, and this could be worse for older adults. In fact, Japan is also experiencing an early and harsh flu season. Japanese news outlet Nippon TV reported that as of November 4, flu cases in Tokyo has surged six times to the level it had seen last year. This data has been confirmed by the Japanese Ministry of Health, Labor, and Welfare. As per the media outlet, more than 2,300 day cares and schools were partially closed.
H3N2, which is a strain of influenza have had some cases in the US, where people reported positive for flu. However, the Centers for Disease Control and Prevention (CDC) has not provided any detailed national report on flu since September 26, ever since the government shutdown happened.
Every February, global health experts and vaccine manufacturers decide which flu strains should be included in the Northern Hemisphere’s fall vaccine, based on the strains circulating in the Southern Hemisphere. This year’s flu shot targets three strains, two influenza A types and one influenza B.
While the annual flu vaccine doesn’t always prevent infection, it significantly reduces the severity of illness. Last year, it was up to 55% effective in preventing hospitalizations among adults with the flu.
On Tuesday, U.K. health authorities reported early data showing that this year’s vaccine is up to 40% effective at preventing hospitalizations in adults.
Despite the variation in effectiveness, experts stress the importance of getting vaccinated. “Decades of data show that even when the match isn’t perfect, the flu shot continues to prevent hospitalizations, ICU admissions, and helps keep people out of the cemetery,” said Dr William Schaffner, an infectious disease expert at Vanderbilt University Medical Center, in Nashville, Tennessee, as reported by NBC.
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