One of the commonest causes of illness, a sore throat often clears up on its own, but knowing what's causing it is important to treat it properly. Viral, bacterial, or caused by allergic elements - these kinds of sore throats have different characteristics that need different responses.

Sore throats have several origins, including infection and environmental factors. Some common causes include:

Viral infections: Viruses cause 90% of sore throat cases. Sore throats may result due to flu or common cold as well as those from chickenpox and measles that can all cause irritation.

Bacterial Infections: Streptococcus bacteria, the most common cause of strep throat, is the most common bacterial source. Strep throat is contagious and can lead to complications if untreated.

Allergies: Pollen, pet dander, and mold can trigger throat irritation, often accompanied by postnasal drip, sneezing, and watery eyes.

Environmental Factors: Dry air, pollution, and smoke can dry out or irritate the throat, creating a scratchy sensation.

Other Causes: GERD, vocal strain, even tumors may be responsible for chronic sore throats.

How to Distinguish Between Viral, Bacterial, and Allergic Sore Throats

Determining your cause of sore throat requires analysis of symptoms that accompany it, how long the sore throat lasts, and how bad the sore throat is.

Viral Sore Throats

The viruses that cause a sore throat are usually similar to a cold in their symptoms and tend to be milder than bacterial infections.

Symptoms of Viral Sore Throat

- Red, swollen throat without white patches

- Persistent cough

- Runny nose and nasal congestion

- Fever, usually mild

Duration: Viral infections last for 7–10 days without antibiotics.

Treatment: Home remedies, such as warm fluids, saltwater gargling, and over-the-counter pain relievers can help alleviate it.

Also Read: Flu Season Grips 40 States In US, CDC Reports Alarming Numbers

Bacterial Sore Throats

Bacterial sore throats, mainly strep throat, are more severe and require prompt medical attention to prevent complications.

Symptoms of Bacterial Sore Throat

- Red and swollen tonsils with white patches or streaks of pus

- High fever

- Absence of a cough

- Nausea, vomiting, or stomach pain (especially in children)

- Small red spots on the roof of the mouth

Diagnosis: Rapid strep tests or throat cultures confirm the presence of bacteria.

Treatment: Antibiotics are necessary to eliminate the infection. Without treatment, complications like rheumatic fever or abscesses can develop.

Sore Throats Caused by Allergies

Throat irritation is caused by postnasal drip. Allergies create a buildup and drip of mucus down the back of the throat.

Allergic Sore Throat Symptoms

- Irritation of the throat and ears

- Runny eyes, sneezing, and nasal congestion

- These symptoms are usually relieved by antihistamines or removal from the source of the allergen

Duration: Allergic sore throats are sustained for as long as the allergens are exposed.

When to Seek Medical Care?

A sore throat should be taken to a doctor if:

- The condition lasts more than a week.

- There is shortness of breath or swallowing becomes painful.

- Swelling is too pronounced or the pain in the throat is extreme.

- High fever, rash, or joint pain occur along with the sore throat.

- A child shows signs of dehydration or refuses fluids due to throat pain.

Early diagnosis can prevent complications and speed recovery.

Effective Treatment for Sore Throats

Home Remedies for Viral and Allergy-Related Sore Throats

Viral infections and allergies often respond well to non-invasive treatments:

• Drink warm teas, broths, or water to soothe the throat.
• Gargling with warm, salty water can reduce inflammation.
• These help soothe an irritated throat and can alleviate coughing.

Let your body rest sufficiently. Humidifying dry air will help keep the throat moist, especially when winter is on its way.

Why Not All Sore Throats Require Antibiotics?

Bacterial infections require antibiotics such as penicillin or amoxicillin. Finish the treatment completely to avoid reoccurrence or resistance.

How to Keep Sore Throats at Bay When Winter Is Near

Prevention is better than cure, and simple lifestyle changes can reduce your risk:

• Wash your hands frequently to avoid infections.
• Avoid close contact with sick individuals.
• Use air purifiers to minimize exposure to irritants.
• Stay hydrated and maintain a balanced diet to boost immunity.

Understanding the cause of your sore throat—whether viral, bacterial, or allergic—is key to effective treatment and recovery. While many sore throats resolve on their own, seeking timely medical advice for persistent or severe symptoms can prevent complications. Prioritize self-care, and don’t hesitate to consult a doctor when needed. Remember, your throat’s health is a vital part of your overall well-being.

An international team of researchers has developed an artificial intelligence (AI)-based tool that can significantly improve care for glaucoma -- a leading cause of irreversible blindness worldwide, according to a study published in The Lancet Primary Care journal today.

Researchers led by those from the University of Lisbon in Portugal found that the AI-based screening tool halved the number of unnecessary referrals for glaucoma.

The study, released during the Glaucoma Awareness Week, also showed an accuracy level at par with human eye doctors.

"The high accuracy at excluding people without glaucoma is especially important, as false alarms can lead to unnecessary hospital visits, patient anxiety, and added strain on healthcare services," the researchers said.

According to the researchers, AI-based screening could:

• support earlier detection,
• reduce unnecessary specialist referrals,
• prevent avoidable vision loss,
• can be integrated into routine primary care in a cost-effective way

Key Findings

The study was carried out at a single screening center in Lisbon, Portugal, in 2023.

The experts screened 671 adults aged 55-65 for glaucoma via the AI tool, analyzing images of the eyes. The images were then independently graded by six glaucoma experts.

The AI-tool:

• referred 66 people (9.8 percent) vs 118 referrals (18.0 percent) by the eye doctors,
• diagnosed glaucoma in 40 participants (6.4 percent).
• It correctly identified 78 percent of people who truly had glaucoma, vs 75 percent identified by the eye doctors
• Correctly ruled out the disease in 95 percent of people, vs 91 percent by eye doctors

While modelling studies suggest that screening could substantially reduce glaucoma-related visual impairment and blindness, barriers include the need for specialised diagnostic equipment and trained personnel, particularly in low- and middle-income countries, and the intrinsically low positive predictive value of screening tests.

In such a scenario, the new study showed that "AI may provide a more viable option than population-wide screening", which may seem impractical.

What Is Glaucoma?

Glaucoma is a chronic disease that affects an estimated 80 million individuals globally, according to the World Glaucoma Association.

It is a progressive, degenerative disorder of the optic nerve that produces characteristic visual field damage.

The disease stems from a long asymptomatic phase, resulting in substantial underdiagnosis and delayed treatment.

Even in high-income countries, up to 50 percent of individuals with glaucoma remain undiagnosed, frequently presenting moderate to advanced disease at first detection.

By the year 2040, it is estimated that there will be 22 million individuals worldwide who are blind from glaucoma.

When to see a doctor for glaucoma:

• Vision suddenly gets blurry
• Severe eye pain
• Headache
• Nausea
• Vomiting
• Rainbow-colored rings or halos around lights

In adults, long periods of sleep deprivation has been linked to problems such as weakened immunity, weight gain, depression, and an increased risk of dementia. However, scientists are now paying closer attention to how sleep affects the brain much earlier in life.

However, a new University of North Carolina School of Medicine study suggests that disrupted sleep during early childhood may interfere with key stages of brain development and asl well as increase the risk of developing autism.

Why Sleep Matters For The Developing Brain

From the moment babies are born, their brains are rapidly developing. During this stage, neurons form connections with one another through structures called synapses. These connections allow brain cells to communicate and are essential for learning, attention, working memory, and long term memory.

Sleep plays a crucial role in helping these synapses form and strengthen. During sleep, the brain organizes and stabilizes these neural connections, shaping the foundation for future brain function. If sleep is repeatedly disrupted during this delicate stage of development, the process may be affected.

Frequent waking or sleep disturbances could interfere with how these neural connections are formed, potentially influencing behavior and cognitive abilities later in life.

The Link Between Sleep And Autism

Sean Gay, a graduate student in the laboratory of Graham Diering, PhD, assistant professor in the Department of Cell Biology and Physiology at the UNC School of Medicine and lead author said that more research was needed to determine the exact link between sleep and the development of autism.

“The unique effects of sleep loss during development are largely unexplored,” Diering said. “Our data show that babies and children are more vulnerable to the negative effects of sleep disruption. We also found that sleep loss during this crucial period of time can negatively interact with underlying genetic risk for autism spectrum disorder.”

Sleep problems are already known to be common in people with autism. In fact, sleep disruption has been reported in more than 80 percent of individuals with autism spectrum disorder. However, researchers have long debated whether these sleep issues are a cause of the disorder or a consequence of it. Understanding how sleep interacts with brain development could help scientists detect autism earlier and potentially develop new treatment strategies.

Studying Sleep Disruption In Early Life

In earlier work conducted in 2022, researchers examined how sleep disruption during early life might interact with genetic factors linked to autism. Using mouse models, they disrupted sleep during the third week of life, a developmental stage roughly comparable to ages one to two in humans.

The study found that sleep disruption during this period produced long lasting behavioral changes. Male mice that were genetically vulnerable to autism showed deficits in social behavior later in life. These results suggested that sleep disruption during critical stages of development may interact with genetic risk factors in ways that shape long term behavior.

Younger Brains Respond Differently To Sleep Loss

To investigate further, researchers studied how developing and adult mice respond differently to sleep deprivation.

Using specially designed housing systems equipped with sensitive sensors, scientists tracked the animals’ breathing and movement. This allowed them to determine when the mice were awake and when they were asleep.

The researchers observed that adult mice were able to compensate for lost sleep. After experiencing sleep deprivation, the adults increased their sleep later during their normal active period. This process, known as sleep rebound, allowed them to recover some of the lost rest.

Younger mice behaved very differently. They showed no sleep rebound at all, meaning they did not compensate for the sleep they had lost. This finding suggests that younger brains may be far more vulnerable to the effects of sleep disruption.

The consequences were also visible in cognitive performance. Sleep deprived young mice performed poorly on learning and memory tasks, while adult mice were significantly more resilient after losing sleep.

Changes At The Level Of Brain Synapses

The researchers also examined what was happening inside the brain at the molecular level. Synapses are the points where neurons communicate, and they play a central role in memory formation and learning. Because sleep is closely linked to how synapses function, the team analyzed how sleep deprivation affects these structures. Using advanced protein analysis techniques, researchers mapped changes in the proteins that regulate synapses.

The results showed that sleep deprivation in young mice significantly altered the formation of synapses. These changes were not seen in adult mice. “This now provides one of the largest and most comprehensive datasets to examine the molecular effects of sleep loss across the lifespan,” Diering said.

Potential Future Treatments

The research team hopes their findings may eventually help guide the development of new treatments for autism and other neurodevelopmental conditions. One goal is to create sleep based therapies for children that work differently from traditional sleep medications. Instead of acting as sedatives, these treatments would target the biological mechanisms that regulate synapses and sleep function.

“Development is not something that one can go back and do again,” Diering said. “Sleep is important for the entire life and especially during development. Understanding what we know now will place greater emphasis on understanding sleep issues in ASD and could lead to an important therapeutic avenue to treat ASD and other developmental conditions.”

The findings highlight an important message for parents and caregivers. During early childhood, healthy sleep patterns may play a critical role in shaping the brain for years to come.

Using amphetamines, cocaine and cannabis can significantly increase your risk of having a brain stroke particularly among younger adults, according to a new University of Cambridge analysis

The findings highlight how recreational drug use may contribute to a preventable health risk, especially among people under the age of 55.

Megan Ritson, a stroke genetics researcher at the University of Cambridge and lead author said the results provide strong evidence linking certain drugs to stroke risk.

“These findings provide compelling evidence that drugs like cocaine, amphetamines, and cannabis are causal risk factors for stroke,” Ritson noted.

A stroke occurs when blood flow to part of the brain is interrupted. This can happen when a blood vessel becomes blocked by a clot, known as an ischemic stroke, or when a blood vessel bursts and causes bleeding in the brain, known as a hemorrhagic stroke. Both types can lead to serious brain damage and can be life threatening.

Amphetamines Associated With The Highest Risk

Among the substances examined, amphetamines were linked to the largest increase in stroke risk. Amphetamines are powerful stimulants that affect the central nervous system and can significantly increase heart rate and blood pressure. In illegal forms, they are often sold under street names such as meth or ice.

When researchers combined data from eight previous studies, they found that recreational amphetamine use was associated with more than double the risk of stroke across all adult age groups. For individuals under the age of 55, the increase was even greater. In this group, amphetamine use was linked to nearly triple the risk of stroke compared with people who do not use the drug.

Across all age groups, the analysis found that amphetamine use increased the risk of ischemic stroke by 137 percent and hemorrhagic stroke by 183 percent. These figures reflect relative risk, meaning the probability of stroke is higher among users compared with non users.

Cocaine Shows A Similar Pattern

The researchers also found a strong association between cocaine use and stroke. Cocaine is another central nervous system stimulant that can raise blood pressure and constrict blood vessels. These effects may increase strain on the brain’s blood vessels and raise the likelihood of both clot formation and vessel rupture.

The analysis showed that cocaine use nearly doubled the risk of stroke of any kind and more than doubled the risk of hemorrhagic stroke. Additional genetic investigations were conducted alongside the main analysis to better understand whether the relationship might be causal rather than simply linked to other lifestyle factors.

Eric Harshfield, a genetic epidemiologist at the University of Cambridge, said the findings suggest the drugs themselves may play a direct role. “Our analysis suggests that it is these drugs themselves that increase the risk of stroke, not just other lifestyle factors among users,” Harshfield said.

Cannabis Linked To Smaller But Significant Risk

Compared with amphetamines and cocaine, the association between cannabis use and stroke was smaller but still statistically significant. Researchers reviewed 19 previous studies investigating cannabis use and stroke outcomes. The analysis found that recreational cannabis use was associated with a 16 percent increase in the risk of any stroke and a 39 percent increase in the risk of ischemic stroke.

Among people under the age of 55, cannabis use was linked to a 14 percent increase in stroke risk. Although the increase is lower than that associated with stimulant drugs, researchers say it remains important because cannabis is widely used.

Opioids Showed No Clear Association

The analysis did not find evidence linking opioid use to an increased risk of stroke. However, researchers caution that stroke risk can be influenced by many factors. These include how long a person has used a drug, how much they use, their overall health, diet, genetics, and socioeconomic environment. Heavy alcohol use is also known to increase the risk of stroke and may worsen the effects of other substances.

A Preventable Health Risk

Experts say the findings highlight the need for greater awareness about how recreational drugs can affect long term health, particularly among younger people who may not associate stroke with their age group. “Illicit drug use is a preventable stroke risk,” Ritson explained. “I don’t know if young people are aware how high the risk is.”

The researchers also note that many of the studies included in the analysis relied on participants reporting their own drug use. Because of this, other lifestyle factors could potentially influence the results. Further research will be needed to better understand the biological mechanisms involved and how different patterns of drug use may affect stroke risk. Still, scientists say the evidence now available provides an important foundation for future public health strategies.

“These findings give us stronger evidence to guide future research and public health strategies,” Ritson said.