Image Credit: Canva
One of the commonest causes of illness, a sore throat often clears up on its own, but knowing what's causing it is important to treat it properly. Viral, bacterial, or caused by allergic elements - these kinds of sore throats have different characteristics that need different responses.
Sore throats have several origins, including infection and environmental factors. Some common causes include:
Viral infections: Viruses cause 90% of sore throat cases. Sore throats may result due to flu or common cold as well as those from chickenpox and measles that can all cause irritation.
Bacterial Infections: Streptococcus bacteria, the most common cause of strep throat, is the most common bacterial source. Strep throat is contagious and can lead to complications if untreated.
Allergies: Pollen, pet dander, and mold can trigger throat irritation, often accompanied by postnasal drip, sneezing, and watery eyes.
Environmental Factors: Dry air, pollution, and smoke can dry out or irritate the throat, creating a scratchy sensation.
Other Causes: GERD, vocal strain, even tumors may be responsible for chronic sore throats.
Determining your cause of sore throat requires analysis of symptoms that accompany it, how long the sore throat lasts, and how bad the sore throat is.
The viruses that cause a sore throat are usually similar to a cold in their symptoms and tend to be milder than bacterial infections.
- Red, swollen throat without white patches
- Persistent cough
- Runny nose and nasal congestion
- Fever, usually mild
Duration: Viral infections last for 7–10 days without antibiotics.
Treatment: Home remedies, such as warm fluids, saltwater gargling, and over-the-counter pain relievers can help alleviate it.
Also Read: Flu Season Grips 40 States In US, CDC Reports Alarming Numbers
Bacterial sore throats, mainly strep throat, are more severe and require prompt medical attention to prevent complications.
- Red and swollen tonsils with white patches or streaks of pus
- High fever
- Absence of a cough
- Nausea, vomiting, or stomach pain (especially in children)
- Small red spots on the roof of the mouth
Diagnosis: Rapid strep tests or throat cultures confirm the presence of bacteria.
Treatment: Antibiotics are necessary to eliminate the infection. Without treatment, complications like rheumatic fever or abscesses can develop.
Throat irritation is caused by postnasal drip. Allergies create a buildup and drip of mucus down the back of the throat.
- Irritation of the throat and ears
- Runny eyes, sneezing, and nasal congestion
- These symptoms are usually relieved by antihistamines or removal from the source of the allergen
Duration: Allergic sore throats are sustained for as long as the allergens are exposed.
A sore throat should be taken to a doctor if:
- The condition lasts more than a week.
- There is shortness of breath or swallowing becomes painful.
- Swelling is too pronounced or the pain in the throat is extreme.
- High fever, rash, or joint pain occur along with the sore throat.
- A child shows signs of dehydration or refuses fluids due to throat pain.
Early diagnosis can prevent complications and speed recovery.
Viral infections and allergies often respond well to non-invasive treatments:
Let your body rest sufficiently. Humidifying dry air will help keep the throat moist, especially when winter is on its way.
Bacterial infections require antibiotics such as penicillin or amoxicillin. Finish the treatment completely to avoid reoccurrence or resistance.
Prevention is better than cure, and simple lifestyle changes can reduce your risk:
Understanding the cause of your sore throat—whether viral, bacterial, or allergic—is key to effective treatment and recovery. While many sore throats resolve on their own, seeking timely medical advice for persistent or severe symptoms can prevent complications. Prioritize self-care, and don’t hesitate to consult a doctor when needed. Remember, your throat’s health is a vital part of your overall well-being.
Credit: Canva
India has reported its second human fatality due to highly pathogenic avian influenza (HPAI) or bird flu, marking the first such death in four years. While bird flu infections in humans are rare, they are highly lethal, with a fatality rate of one in two cases. The most recent victim was a two-year-old girl from Palnadu, Andhra Pradesh, who passed away in mid-March after being hospitalized for over 10 days at the All India Institute of Medical Sciences (AIIMS), Mangalgiri.
The pathogen responsible for the infection and subsequent deaths was confirmed only on 31 March, following a survey by the Indian Council of Medical Research-National Institute of Virology (ICMR-NIV). According to details shared by the state government, the child, who had a habit of consuming raw chicken, was admitted to the hospital on 4 March with symptoms including fever, breathlessness, nasal discharge, seizures, diarrhea, and reduced feeding. Two days before falling ill, she had reportedly consumed raw chicken. She succumbed to the infection 12 days later.
In a statement issued on Wednesday, the state government noted that no abnormal cases of respiratory infections had been identified in the ongoing survey. However, surveillance will continue for the next two weeks, with testing arranged for any suspected cases. Union health ministry officials stated that, based on data from the Integrated Disease Surveillance Programme (IDSP), no unusual surge in influenza-like illness (ILI) or severe acute respiratory illness (SARI) cases has been observed in the district in recent weeks.
A national joint outbreak response (NJOR) team has been deployed to conduct an epidemiological investigation and provide assistance to the state.
The Union government emphasized that "human-to-human transmission of the H5N1 virus is uncommon, and the risk of any other epidemiologically linked case being reported is assessed to be low."
India's first recorded human infection of the H5N1 influenza virus occurred in 2021 when an 18-year-old boy in Haryana succumbed to the infection within days of contracting it.
In May last year, Australia reported its first human infection with H5N1, stating that the patient had acquired the virus in India. Towards the end of 2024, the deaths of four big cats—three tigers and a leopard—were attributed to H5N1 infection.
Oxytocin, commonly referred to as the "love hormone" because it is involved in bonding and social behavior, is now being investigated for its surprise effect on pregnancy. Although oxytocin is traditionally linked to childbirth, milk letdown during lactation, and emotional bonding, recent findings indicate that this hormone can possibly delay early pregnancy. A study on mice conducted recently has helped explain how the hormone can stop embryonic growth, which may provide new understanding of human fertility and pregnancy.
In a few mammals, such as marsupials, bats, and more than 130 others, a process called "diapause" takes place. This is a natural biological phenomenon that sees embryos suspend their development in order to wait until the right conditions prevail for pregnancy to resume. Although very uncommon and hard to monitor in human beings, clinical experience from in vitro fertilization clinics indicates that human embryos might at times show delayed implantation. One highly documented case in 1996 showed that an embryo implanted in a uterus was in a suspended state for five weeks before implantation took place.
The new research by scientists at the NYU Grossman School of Medicine investigated oxytocin's possible role in inducing this pause in pregnancy. Their results indicate that oxytocin could be a major player in controlling diapause in mice, and they raise questions about its possible role in human pregnancies.
To study the impact of oxytocin on pregnancy, scientists tested female mice who had recently given birth by letting them be mated while still lactating. The research revealed that nursing females had pregnancies that lasted about a week longer than those of the non-nursing mice. Since the normal pregnancy in mice takes only 19 to 21 days, this postponement is a drastic halt to embryonic development.
The research team then sought to determine how this pause occurred. Using optogenetics, a technique that enables the activation of specific neurons through light stimulation, they artificially triggered the release of oxytocin in pregnant mice. After five days of oxytocin stimulation, the researchers examined the mice’s uteruses and found that five out of six had embryos in a dormant state, indicative of diapause. Conversely, pregnant mice that were not administered oxytocin stimulation did not exhibit any indication of developmental arrest.
In further confirmation of their research findings, the scientists administered oxytocin to early-stage mouse embryos in the laboratory setting. They detected identical cellular alteration related to diapause, implying that oxytocin has a direct influence on suspended embryonic development.
The research showed that oxytocin slows down the process through which embryonic cells convert genetic information into proteins. This process, essential for growth and development of the cell, is copying DNA instructions into RNA, which then guides protein synthesis. By suppressing this process, oxytocin puts the embryo into suspended animation.
Interestingly, scientists also learned that embryos without oxytocin receptors were still able to enter diapause, suggesting that more than one biological pathway is used to trigger the pause. Still, having working oxytocin receptors seemed to increase the embryo's chances of surviving the halted state. When oxytocin receptors in the embryos were deactivated, survival rates while in diapause fell to 11% from 42%.
Although this research is in its infancy, it presents exciting possibilities for human fertility studies. A better grasp of the role oxytocin plays during early pregnancy may lead to significant advances in treating unexplained infertility and recurrent miscarriage. If human embryos can enter a state of diapause, further study could reveal how hormonal or environmental influences are responsible for early pregnancy loss.
Also, these discoveries may have greater implications outside pregnancy. As oxytocin is implicated in cell survival, researchers now want to know if what it does in diapause can help understand how to keep nerve cells from dying in the developing nervous system. What stops cells from dying early on might help neurobiology and regenerative medicine advance.
Even with these thrilling findings, much remains to be answered. How long can diapause be in various species, including humans? What are other biochemical signals that cooperate with oxytocin to control embryonic development? And might this information one day lead to targeted fertility treatments or interventions?
More studies are needed to uncover these secrets. As researchers learn more about the multifaceted functions of oxytocin, its image as just the "love hormone" is changing. This potent molecule seems to play a much more intricate function in reproductive biology than has been known, and it may play a role not only in when life starts, but in when it temporarily gets suspended.
Oxytocin's role in pregnancy is turning out to be more complex than originally thought. Though still a primary force behind labor and maternal attachment, it has also recently been found to retard embryonic development, which could have far-reaching consequences for reproductive science. As more research unfolds, the hormone could provide new insights into fertility, enhance IVF success, and even prevent early miscarriage. The possibility of oxytocin-based fertility therapies is an exciting one, and future research will be important to determine how this information can be translated to human pregnancy.
Credit: Canva
A study published in the New England Journal of Medicine has listed five key factors that impact the longevity of individuals. The research tracked participants for up to 47 years, assessing how five specific factors influenced their risk of death, longevity, and the number of healthy years they could gain by altering these habits. The conclusions of this study were based on data analyzed from over two million adults aged 18 and above across 39 countries.
As per the researchers, women who didn't have these five risk factors at age 50 could potentially add more than 14 years to their lives, and men could gain almost 12 additional years. Men were most affected by these factors as those with all five faced a 94% chance of dying before 90, while their counterparts without these issues had just a 68% chance. Women with all five risk factors at age 50 had an 88% chance of dying before 90, whereas those without these problems had a 53% chance.
Out of all the factors, cholesterol was the least impactful of all. As per the study, people who lowered their cholesterol levels could only add 1.2 extra healthy years to their lifespan. On the contrary, individuals who quit smoking could potentially extend their lives by up to six years. Women who do not have diabetes could gain an extra 6.4 years, while men without the condition might see an increase of 5.8 years. Even a slight reduction in blood pressure could lead to an additional 1.8 healthy years, and achieving a normal BMI could contribute an extra 2.6 years, with variations depending on the region.
The study reinforces the importance of lifestyle modifications in extending a healthy lifespan. The researchers noted that small but consistent changes in daily habits could significantly impact longevity. For example, maintaining an optimal weight through a balanced diet and regular physical activity helps control blood pressure, diabetes, and cholesterol levels, reducing overall health risks.
Smoking cessation emerged as the most crucial lifestyle change that could dramatically influence lifespan. Quitting smoking, even later in life, significantly reduces the risk of cardiovascular diseases, lung disorders, and certain cancers, contributing to longer and healthier lives. Similarly, diabetes management through dietary changes, regular exercise, and proper medical intervention plays a vital role in preventing complications and enhancing longevity.
The study also highlighted variations in longevity gains based on gender and geographical regions. For instance, men were more susceptible to the adverse effects of these five risk factors than women. This disparity could be attributed to lifestyle differences, genetic predisposition, or healthcare access.
Additionally, in certain countries with high obesity rates, maintaining a normal BMI was one of the most significant contributors to longevity. Meanwhile, in regions with lower tobacco consumption, factors like high blood pressure and diabetes had a more prominent role in affecting lifespan.
© 2024 Bennett, Coleman & Company Limited