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Quademic 2025: Hospitals in the United States are dealing with a surge in patients admission, the reason is the quademic it is dealing with at this moment. This has led to an influx of patients. It is all caused by seasonal infections, including common flu, Covid-19, and respiratory syncytial virus (RSV) that dominate the winter season in the US. This year, norovirus also joined the list, which has further increased the load on the healthcare.
The healthcare company founded in academics M Health Fairview, confirmed that their hospitals are overflowing due to the quademic.
The hospitals of M Health Fairview's volume is up by 30% and as a results, patients are being treated in the hallways and in alternative care areas. There is also a longer wait time and shortages for resources that are required to treat these emergencies. This has also impacted other life-threatening emergencies like heart attacks and strokes, as the healthcare resources and caregivers are occupied with the surge in seasonal cases.
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Common cold and flu: The common cold and influenza (flu) are perhaps the most well-known illnesses that peak during the fall. As temperatures drop and humidity levels fluctuate, viruses that cause colds and the flu become more active. The flu, in particular, can be more severe than a common cold, leading to complications such as pneumonia, especially in vulnerable populations like the elderly and those with pre-existing health conditions. Symptoms include a runny nose, sore throat, coughing, fever, and body aches.
Covid-19: As per the World Health Organization, Coronavirus disease or COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Most people infected with this virus will experience mild to moderate respiratory illness and recover without requiring special treatment, However, there could be some cases of seriously ill patients who may require medical attention. It is also because of the other existing medical conditions like cardiovascular diseases, diabetes, chronic respiratory diseases, cancers, or older age.
The best way to protect against this virus is by following social isolation form those who are infected, using mask to prevent droplets from infecting others when you cough or sneeze and to wash your hands for 20 seconds frequently.
RSV or Respiratory Syncytial Virus: As per the Centers of Diseases Control and Prevention (CDC), RSV is a common respiratory virus that infects nose, throat and lungs. Though symptoms are similar to the viruses like flu or COVID-19, the disease in itself is different. It also peaks during the winter season, especially between December and January.
However, the main difference between RSV and other respiratory illness, above mentioned is that RSV can cause pneumonia or bronchiolitis, especially for those who are over the age of 50 or with an existing heart or lung disease.
Norovirus: It is a number 1 cause of foodborne illness in the US and this happens when virus gets into the food and then it accidentally enters your mouth. These particles are from faeces or vomit from infected people, or can be transmitted via contaminated food and water. It could also spread by touching unclean surfaces like door handles or cutlery.
For most people, having norovirus is unpleasant, but mild and recovery could be made in 1 to 2 days. However, it could be more serious for babies, older people and anyone with any existing health condition.
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Sixty-two deaths in Australia have been reported to the medicines regulator, the Therapeutic Goods Administration (TGA), with suspected associations with GLP-1 medicines, including Ozempic, Wegovy and Mounjaro.
The TGA has also received reports of nearly 3,000 serious adverse events involving these medicines, which are used by hundreds of thousands of Australians, The Herald Sun reported.
Reported adverse reactions include nausea, pancreatitis, suicidal thoughts and a rare eye condition that can cause blindness.
Semaglutide, the active ingredient in Ozempic, used for type 2 diabetes, and Wegovy, approved for weight management, had the highest number of reported deaths with suspected associations.
Other medicines with reported suspected associations include Mounjaro (tirzepatide), Saxenda (liraglutide) and Trulicity (dulaglutide). These drugs are approved to treat type 2 diabetes, obesity, or both.
The reported deaths included:
The TGA states that adverse-event reports alone cannot determine how common a reaction is or be used to directly compare the safety of different medicines. The regulator also said the benefit-risk profile of these medicines remains positive when they are appropriately used for approved indications and in intended patients.
The TGA recently updated warnings for some GLP-1 medicines concerning non-arteritic anterior ischaemic optic neuropathy (NAION), a rare but serious eye condition.
Product warnings across the glucagon-like peptide-1 receptor agonist (GLP-1 RA) class have been updated because of the potential association with the disorder.
NAION can cause permanent visual impairment, including blindness. The TGA notes that no treatment has been shown to improve visual acuity outcomes in people who develop the condition.
GLP-1 RA medicines are prescription drugs used primarily to manage type 2 diabetes and obesity. Thus, the TGA urged patients not to stop treatment on their own.
“These are prescription medicines, so people taking them should discuss benefits, risks and side effects with their healthcare professional rather than stopping or changing treatment based on headlines alone,” the TGA said.
The Australian reports come amid safety monitoring of GLP-1 medicines in other countries. At the same time, clinical evidence has shown important health benefits from some GLP-1 medicines, including reductions in cardiovascular risk and, in certain populations, overall mortality.
Data submitted to the UK's Medicines and Healthcare Products Regulatory Agency (MHRA) showed 82 reported deaths associated with GLP-1 receptor agonists up to January 31, 2025. Of these, 22 were associated with use for weight loss and 60 with use for type 2 diabetes.
In the US, reports in the FDA's FAERS (FDA Adverse Event Reporting System) database have listed 162 deaths associated with Ozempic and Wegovy since 2018.
However, these figures should not be interpreted as confirmed deaths caused by the medicines. Adverse-event reporting systems record suspected associations and cannot by themselves establish a direct causal relationship. Millions of people use GLP-1 medicines, and reported cases can involve other health conditions or factors, including severe complications, dosing errors, and counterfeit or compounded products.
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English singer-songwriter Robbie Williams has opened up about being diagnosed with “a little bit of autism” and shared his struggles with intrusive thoughts.
The 52-year-old singer revealed that he had earlier been diagnosed with ADHD, as well as Tourette’s syndrome, the Daily Mail reported.
Speaking at the launch of his clothing brand Hopeium at Flannels, Williams said his autism diagnosis has helped explain some of his behaviors.
“I have ADHD and I just found out I have a bit of autism as well, which I actually f*****g love because it explains so much,” he said.
The British pop icon said he now sees the diagnosis as an explanation for “all the weird” things he does. He also described how ADHD affects his ability to concentrate.
“With the ADHD you can completely and utterly concentrate on something 1000 per cent, but with absolutely everything else, you just cannot do it. Ask my kids,” he said.
The singer said he is “completely and utterly obsessed with creating images and making funny things”.
Williams, who has won a record 18 BRIT Awards, said creativity helps him redirect his thoughts and avoid focusing on things that make him panic or feel scared.
“My brain is incredibly creative, and it can be creative about everything in the world that you panic or are scared about,” he said.
He gave the example of sitting on a plane and having an intrusive thought about possessing telekinetic powers and causing the plane to crash.
He said he has learned to “train my brain to do something better” rather than focusing on worrying thoughts.
Autism is a neurodevelopmental condition that can affect communication, social interaction and behavior. It is a spectrum, meaning symptoms and their severity can vary widely between individuals.
Common characteristics can include repetitive behaviors or interests, difficulty with changes in routine and challenges in social situations.
Williams has also previously spoken about being diagnosed with Tourette’s syndrome. In a recent podcast, he said he had realized that some of the intrusive thoughts he experiences may be connected to Tourette’s, although he does not experience the typical outward tics.
“I've just realized that I have Tourette's, but they don't come out. They are intrusive thoughts that happen,” Williams said.
He also spoke about struggling to fully take in the reaction of audiences, despite performing in front of large crowds.
Williams has said he was diagnosed with ADHD three times because he “forgot” that he had previously been told he had the condition. He first recalled being diagnosed around 2006 after recognizing ADHD symptoms while reading about the condition online.
After his diagnosis, he said he began taking a large number of tablets in the hope that they would “fix” him. He later said his substance misuse escalated, including crushing and snorting the pills.
Williams has faced several addictions and has had multiple stays in rehabilitation since rising to fame in the early 1990s.
ADHD is a neurodevelopmental condition that can involve persistent difficulties with attention, organization and impulse control.
Symptoms can include being easily distracted, forgetfulness, losing things and difficulty maintaining concentration. Some people may also experience restlessness and impulsive behavior.
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A 40-year-old woman developed a rare and potentially life-threatening “flesh-eating” infection of the genital and perineal region about a week after shaving her bikini line and an application of herbal preparation.
The woman, a mother of four with a BMI of 39 kg/m², was diagnosed with Fournier gangrene, a severe form of necrotizing fasciitis that can rapidly destroy soft tissue around the genitals and perineum.
She spent 77 days in hospital undergoing treatment, wound care and reconstruction. Complete wound healing was documented by Day 121, reported doctors from King Saud University in Riyadh, Saudi Arabia, in the American Journal of Case Reports.
The woman presented with worsening pain and swelling of the left labia that had spread toward the area above the pubic bone. She also experienced vomiting and lower abdominal pain.
About a week before admission, she had undergone perineal shaving and had a herbal preparation applied to her vulva by an alternative practitioner. She had not used antibiotics or other topical treatments before seeking medical care.
On admission, her heart rate was elevated at 140 beats per minute, although she had no fever and her blood pressure remained normal. Examination showed marked tenderness and swelling, while laboratory tests indicated a significant inflammatory response.
Samples taken from the infected wound grew several different types of bacteria (E. coli, Klebsiella pneumoniae, and Enterobacter cloacae). However, no bacteria were detected in her bloodstream.
After doctors diagnosed her with Fournier gangrene, they performed urgent surgical debridement to remove the affected tissue.
She subsequently underwent multiple surgical re-explorations and negative-pressure wound therapy.
She was initially given broad-spectrum antibiotics, and later amoxicillin-clavulanate.
Fournier gangrene is a rare, rapidly progressive form of necrotizing fasciitis affecting the perineum and external genitalia. It is often described as a “flesh-eating” infection because bacteria can cause rapid destruction of skin and underlying soft tissue.
The condition is much more common in men, but women can also develop it. Reported male-to-female ratios range from 10:1 to 40:1.
Risk factors include diabetes, obesity, immunosuppression, malnutrition, peripheral vascular disease, kidney disease, malignancy and other serious underlying conditions. However, Fournier gangrene can also occur in people without the classic risk factors.
Local trauma, disruption of the skin barrier and invasive or cosmetic procedures can potentially provide an entry point for infection.
The researchers noted that Fournier gangrene may be underrecognized in women, partly because its symptoms can initially resemble a gynecological condition.
Early symptoms may include severe pain, swelling, redness and tenderness around the genital or perineal area. As the infection progresses, tissue destruction, skin discoloration, blisters or systemic signs of severe infection may develop.
"While men are more frequently affected, women should not be assumed to be at low risk. Severe or rapidly worsening pain and swelling around the genital or perineal region, particularly when accompanied by systemic symptoms, warrants urgent medical evaluation," the team said.
Treatment generally requires emergency surgical removal of dead and infected tissue along with broad-spectrum antibiotics and intensive supportive care. Survivors may require multiple operations, prolonged hospitalisation and complex wound management.
Fournier gangrene is a medical emergency. Although rare, it can progress rapidly and become fatal if treatment is delayed.
The condition has historically been associated with high mortality, with risk increasing when diagnosis and surgical treatment are delayed.
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