We have all seen movies where right before the hero starts fighting, he cracks his knuckles and makes it look like the coolest thing in the world! But then our parents told us that you should not crack your knuckles because that weakens your grip and hand strength. But is that true? While many people do say that they experience a small loss in strength immediately after they crack their knuckles, but are their long-term effects to it? And what is the sound actually coming from?

The reason why people crack their fingers is because the evident and sharp crack noise causes a sense of relief. Many people also do it when they have done an activity that required them to work with their hands a lot like typing or sewing, giving themselves a sense of satisfaction, similar to stretching after doing hard work. That "crack" sound can make some people cringe, while others find it strangely satisfying. Cracking your knuckles is a pretty common habit, but there are a lot of misunderstandings about it. Some people do it without even thinking, others can't stand the noise, and some can't crack their knuckles at all. You might have been told as a kid that it causes arthritis or makes your fingers swell up. But those are just old wives' tales. There's a real science behind this habit, and it's more interesting than you may think.

Why Do Knuckles Make That Popping Sound?

The "crack" isn't actually bones breaking or anything bad happening to your joints. It's a normal thing called "crepitus." This just means harmless popping, snapping, or grinding sounds that come from your joints. The main reason you hear this sound is because of gas bubbles in the fluid that cushions your joints. This fluid is called synovial fluid. When you move or stretch, these tiny bubbles form and then pop, making the sound. It's totally normal and doesn't hurt you. Sometimes, especially in bigger joints like your knees, shoulders, or ankles, the sound can also happen when the stretchy tissues that connect your bones (ligaments and tendons) move slightly and then snap back into place.

After you crack your knuckles, you can't usually do it again right away. You have to wait a bit. That's because the gas bubbles in your joint fluid have already popped, and it takes a little while for them to build up again. While cracking your knuckles doesn't give you arthritis, doing it too much might cause some problems. Doctors say that cracking them too often could make your joints a little wobbly and might even make your grip weaker. Also, if the stretchy tissues in your joints keep snapping over your bones, they can get irritated and sore.

When Joint Popping Might Mean Something More

Sometimes, a pop in your joint is just like cracking your knuckles, nothing to worry about. But other times, it can be a sign of something else. As we get older, the cushiony stuff in our joints, called cartilage, can start to wear down. This cartilage helps your bones move smoothly. When it gets thin or uneven, the bones can rub together, and that can make a grinding or popping sound. This is different from the pop you get from gas bubbles. If this grinding sound happens along with pain, it could be a sign of osteoarthritis. This is a type of joint problem that's more common in older people, but younger people can get it too, especially after a joint injury. If your joints hurt, especially in the morning or after you've been sitting still for a while, feel wobbly, or are hard to move, it's a good idea to see a doctor.

This Is Endometriosis, a 2024 intimate, expressive film by Georgie Wileman and Matt Houghton won a BAFTA Award 2026 for Best British Short Film. This 19.27 minute long film shows how Georgie was robbed of her time due to endometriosis. The film sets in present-day narrative with memories from her past.

Endometriosis is a condition, that Georgie notes is often dismissed by many doctors as just "painful periods". However, her film portrays how truly disabling this medical condition. It is a condition in which cell similar to the lining of the uterus or the endometrium, grow outside the uterus. It affects 1 in 10 born with a uterus and could cause pain, often "worse than the last stages of child labour", notes thisiseno.com, the official website of the short film. Around 190 million people worldwide are impacted by the condition, however, what the film points out is how "dangerously underfunded, under researched and misinformed" doctors continue to remain despite the condition being so widespread.

Read: A Woman Lost Her Ovary To Endometriosis Surgery After Receiving An Ultimatum From Gynecologist

A Film That Documents Personal Struggle

Georgie, while accepting the award wore a symbolic blood-red gown. She said, "It was surreal and beautiful. Knowing how much this win would mean to the [endometriosis] community made it an emotional moment."

She points out that it is more than just a "painful period" and that "It is a full body disease. It important for people to understand the severity of the pain – it’s widely considered to be worse than childbirth." What is shocking is that it takes an average of eight to 10 years to be diagnosed.

She shares being "bed-bound for three months" when she was only 13. She said it first got "really bad" and she was not believed for long time. "It took me a long time to even believe myself. I was just so angry at my body for not working."

While she had been in and out of wheelchair, she was not formally diagnosed with endometriosis until she was 26, and then at 29, she was diagnosed with its 'sister disease' adenomyosis. She has undergone seven surgeries for her endometriosis and a hysterectomy for adenomyosis.

Read: Keltie Knight Was Gaslit By Doctors For Years Before Getting A Hysterectomy

In 2020, after years of feeling dismissed by doctors and watching her condition be misunderstood in the media, she decided she had had enough. That frustration pushed her to tell the story herself.

“It began as a photography project,” Wileman says. “And it meant a lot to people because, for the first time, they felt their experiences were being shown truthfully.”

But she soon realized that still images could only go so far. “There’s only so much a photograph can capture,” she adds.

Why Does It Take So Long For An Endometriosis Diagnosis?

A study published in Obstetrics and Gynecology journal looks at the factors of what leads to such a delay in endometriosis diagnosis. Researchers identified that factors include normalization of menstrual pain, the diversity of symptoms, and a lack of training and prompt referrals among healthcare professionals lead to this delay.

At an individual level, the researchers found that many women struggled to tell the difference between “normal” period pain and something more serious. A common belief was that painful periods were simply part of being a woman and had to be endured. As a result, many relied on self-care measures and delayed seeking medical help, which likely pushed back the timeline for an endometriosis diagnosis.

On an interpersonal level, stigma played a powerful role. Menstrual problems were often seen as too private or embarrassing to talk about. At the same time, society’s tendency to normalize period pain meant that symptoms were minimized, both by those experiencing them and by people around them. This silence and normalization further contributed to delayed diagnoses.

Barriers also existed within the healthcare system itself. Some participants said their general practitioners dismissed their concerns or appeared unfamiliar with endometriosis. Healthcare professionals involved in the study acknowledged gaps in their own training and pointed out the lack of clear clinical guidelines for diagnosing the condition.

Doctors also noted that endometriosis symptoms can overlap with other disorders, making it harder to identify. Diagnosis is particularly challenging because there is no simple, noninvasive test that can confirm the condition with certainty. Delays in referrals were common. One contributing factor was the widespread belief that laparoscopic surgery is the only definitive way to diagnose endometriosis. Some healthcare providers also questioned how useful a formal diagnosis would be, which further slowed the process.

Dr Sophie Davenport, a doctor in England who conducted the research as part of her Master of Public Health dissertation, emphasized that the problem is layered and requires solutions at multiple levels.

“The key highlights of the data are that delays to diagnosis exist throughout the journey,” she explained. “We need to address these at different levels — from society understanding what ‘normal’ menstruation looks like and being open about menstrual problems, to clinicians being well educated, up to date on how endometriosis presents and diagnosed, and truly listening when patients say their periods aren’t normal.”

Squirrels could be natural hosts of the mpox virus (MPXV) -- that causes monkeypox disease -- according to a recent study by German researchers.

The team from the Helmholtz Institute for One Health (HIOH) identified the fire-footed rope squirrel (Funisciurus pyrropus) as a likely natural reservoir of the MPXV.

The study published in the journal Nature revealed that sooty mangabeys – a primate found in West Africa -- can contract mpox by eating infected squirrels. The disease may present mild lesions, but it can also cause more severe skin lesions or even be fatal.

"Identifying the animal sources of the virus and the exposure routes that lead to inter-species transmission are key steps towards understanding spillover mechanisms and developing effective prevention measures to mitigate the risk of transmission to humans," said Livia V. Patrono, one of the senior authors at HIOH.

Squirrels Suspected MPXV Hosts

While squirrels have long been suspected as potential reservoirs for MPXV, their role was confirmed after an investigation of an mpox outbreak among wild sooty mangabeys (Cercocebus atys) in Côte d'Ivoire.

During the outbreak, reported in early 2023, nearly one-third of the primates showed clinical signs of disease, and four infants died.

The team conducted viral genome sequencing and found that the infected monkeys carried a virus that was nearly identical to an MPXV strain identified in a fire-footed rope squirrel found dead 12 weeks earlier nearby.

Further, the team analyzed fecal samples from the mangabeys. A sample collected eight weeks before the outbreak's onset contained DNA from both the virus and the rope squirrel. This provided strong evidence of interspecies transmission at that moment.

Sooty mangabeys have been previously observed catching and eating fire-footed rope squirrels, which provide a direct route for the transmission of viruses.

Mpox Continues To Spread Globally

Although mpox is no longer a public health emergency, outbreaks of clade I and clade II strains of the mpox virus are continuing in many countries around the world, especially in Africa.

Last week, Madagascar announced the country's first death from mpox, a 3-year-old girl from the island nation’s eastern city of Toamasina.

The WHO has also confirmed that two cases of the recombinant strain – combining genomic elements of clades Ib and IIb of the monkeypox virus (MPXV) – have been identified to date: one in the United Kingdom and one in India.

Mpox is an infectious disease caused by the monkeypox virus (MPXV), part of the Orthopoxvirus genus, which also includes the virus that causes smallpox.

It spreads through close physical contact, including sexual contact, and in some cases through contaminated materials or respiratory droplets.

Symptoms typically include fever, swollen lymph nodes, rash, and/or lesions.

The global health body has also urged all countries to “remain alert to the possibility of MPXV genetic recombination.” It has also urged for continued epidemiological surveillance, sequencing, vaccination of at-risk groups, and infection prevention and control measures.

An international group of scientists has created an artificial intelligence tool that can estimate a woman’s likelihood of developing breast cancer within the next four years.

The AI tool, known as the BRAIx risk score, analyzes mammogram images to generate an individualized risk assessment and flag women who may face a higher chance of developing the disease.

It may not only show the current risk but also predict the future risk, enabling early detection and treatments for a better outcome.

According to the findings published in The Lancet Digital Health journal, nearly one in 10 women ranked in the top 2 percent of risk by the AI tool were diagnosed with breast cancer within four years. This was despite previously receiving a clear screening result.

“These risk scores enable future development of personalized screening pathways to transform population breast cancer screening and save lives,” said corresponding author Helen M. L. Frazer of the University of Melbourne.

Frazer noted that identifying women who appear cancer-free but carry very high risk -- comparable to those with inherited BRCA1 or BRCA2 mutations -- will unravel both hereditary and non-hereditary causes of breast cancer.

From one-size-fits-all screening to personalization

Breast cancer screening programs have significantly lowered mortality rates -- by roughly 40-50 percent among women aged 50 to 74. However, most screening systems still apply the same approach to all women, regardless of individual risk.

Traditional screening tools use genetics, breast density, and questionnaires to estimate breast cancer risk. On the other hand, new AI-based screening tools, such as BRAIx personalizes screening by gathering information already present in breast scan images to better identify who is at higher risk.

“Our results show that conventional mammographic density is a far weaker predictor of breast cancer risk than the BRAIx risk score, even for interval cancers,” the researchers said in the paper. Interval cancers are aggressive tumors diagnosed after a negative mammogram.

The BRAIx Tool

The BRAIx risk score was developed using mammograms from nearly 400,000 women. To prove its efficacy, the AI tool was tested on data from almost 96,000 women from Australia and then confirmed in an independent Swedish population of over 4,500 women.

The findings showed that:

• The BRAIx risk score estimated breast cancer risk more accurately than the traditional risk factors, such as breast density, country of birth, and even family history.

• For the top 2 percent of women with the highest BRAIx risk score, the probability of a cancer diagnosis within 4 years was 9.7 percent -- a risk level exceeding that typically seen in women with inherited BRCA1 or BRCA2 mutations.

The BRAIx risk score can:

• Make breast screening more personalised,
• Improve early cancer detection,
• Reduce false alarms,
• Save lives without increasing costs

Global Breast Cancer Burden

Breast cancer continues to be the most common cancer among women worldwide.

A recent study published in The Lancet Oncology journal predicted that the number of new cases of the deadly disease will reach more than 3.5 million globally in 2050 -- rising by a third from 2.3 million in 2023.

Annual deaths from the disease will also rise by 44 percent -- from around 764,000 to 1.4 million.

However, not smoking, getting sufficient physical activity, lowering red meat consumption, and having a healthy weight can help prevent over a quarter of healthy years lost to illness and premature death from breast cancer.