Pregnancy is accompanied by a lengthy list of do's and don'ts—take prenatal vitamins, no alcohol, exercise carefully, and eat well. But what about when an unplanned health issue presents itself, such as the necessity for a mammogram? For most women, this might not even be something they think about until they are in a position where breast cancer screening is an option.

Perhaps you're over 40 and in need of your yearly mammogram, or perhaps you have a history of breast cancer in your family and you want to keep your screenings current. More emergently, you've found a lump in your breast. So, can you have a mammogram when pregnant? The answer is yes, but there are several things to consider.

Pregnancy creates substantial hormonal changes that affect the body, as well as breast tissue. Estrogen and progesterone's rise causes the breasts to expand and condition to produce milk, which results in denser tissue. This increased density is more challenging to detect any abnormalities with using mammograms. Even post-delivery, should the woman be breastfeeding, milk-filled glands can also make the breasts denser and, as a result, make mammogram readings less clear.

While 3D mammograms have improved imaging technology to help navigate dense breast tissue, doctors often suggest postponing routine screening mammograms until after pregnancy if there are no symptoms or high-risk factors. However, if a lump or abnormality is found, your doctor may recommend immediate diagnostic imaging.

When Is a Mammogram Necessary During Pregnancy?

Mammograms are not done routinely if a woman becomes pregnant, yet there are specific situations where one might be unavoidable. Breast cancer in pregnancy does occur—1 in 3,000 times—but it's not common. If a lump is detected by a woman, she has constant breast pain and no explanation, or she is at high risk (e.g., strong history of breast cancer in her family or genetic defect such as BRCA1 or BRCA2), a physician will order a mammogram.

The process itself takes very little radiation exposure. The radiation employed by a mammogram is concentrated on the breast, and there is little to no radiation that reaches other areas of the body. A lead apron is also placed over the belly to shield the unborn child.

Alternative Breast Imaging Options During Pregnancy

For pregnant women requiring breast imaging, physicians may initially suggest an ultrasound. In contrast to a mammogram, an ultrasound is not done with the use of radiation and is deemed safe for pregnant women.

An ultrasound of the breast can establish whether a lump is a fluid-filled cyst or a solid tumor that needs further investigation. Yet ultrasounds are not always diagnostic, and in certain instances, a mammogram or biopsy is needed to determine or rule out cancer.

Magnetic Resonance Imaging (MRI) is also an imaging choice but has some drawbacks. The majority of breast MRIs employ a contrast material called gadolinium, which is able to pass through the placenta and to the fetus. Although risks are not entirely clear, physicians usually do not use MRI with contrast unless necessary. Some practitioners may offer an MRI without contrast as an option.

What If You Find a Lump In Your Breast During Pregnancy?

Breast changes throughout pregnancy are normal, but finding a lump should never be taken lightly. If you notice a lump, alert your medical provider right away. They will conduct a clinical breast exam and potentially have you get an imaging study such as an ultrasound or mammogram to see whether anything needs to be done.

If imaging indicates a suspicious mass, a biopsy can be suggested. Core needle biopsy is the most frequently used and is safe during pregnancy. It consists of numbing the skin with local anesthetic and inserting a hollow needle into the area to obtain a small sample of tissue to be tested.

Breast Cancer Treatment During Pregnancy

In the extremely uncommon event of a diagnosis of breast cancer while pregnant, therapy will be determined by the nature and extent of cancer and by how far along in pregnancy one is. The most frequent form of treatment is surgery—either mastectomy (surgical removal of the entire breast) or lumpectomy (surgical removal of the lump)—which is usually safe while pregnant.

Chemotherapy is also possible but usually only attempted after the first trimester, when it can damage developing fetal tissue. Radiation therapy is not used during pregnancy and is typically deferred until after giving birth. Hormonal therapy and targeted therapies are also omitted until after giving birth.

Can I Get a Mammogram While Breastfeeding?

Yes, you can have a mammogram while you are breastfeeding. The radiation in a mammogram does not impact breast milk or hurt the baby. But breast density is still high during lactation, and this might complicate detection of abnormalities. To enhance image quality, physicians usually advise breastfeeding or pumping 30 minutes prior to the mammogram.

Routine screening mammograms are usually delayed in pregnancy unless there is a high-level concern.

If a lump is detected, an ultrasound is typically the initial imaging study done, with a mammogram being a consideration if additional assessment is necessary.

• Pregnancy mammograms utilize minimal radiation and are safe when required.
• Breast MRI with contrast is usually avoided in pregnancy.
• Breast biopsy, when necessary, is safe during pregnancy.

If breast cancer does develop during pregnancy, there are available treatment options that can be adjusted to keep the mother and infant safe.

Pregnancy is a period of significant change, and health issues particularly those involving breast health, are anxiety-provoking. Routine mammograms are typically postponed until after giving birth, but diagnostic testing can be done if necessary. The best you can do is discuss changes you notice in your breasts with your healthcare provider in an open manner. Early detection and prompt treatment can make a very big difference in the health of both mother and fetus.

Aging is a significant factor in memory loss and cognitive decline. Now, a team of US researchers has pinpointed a single protein that drives these changes in the brains of the elderly.

In aging mice, higher levels of protein FTL1 weakened connections between brain cells, leading to memory decline.

But when FTL1 was reduced, the brain began to recover. It also rebuilt lost connections and restored memory performance, according to the study, published in Nature Aging.

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"It is truly a reversal of impairments," said Saul Villeda, Associate Director at the University of California - San Francisco's Bakar Aging Research Institute and senior author of the paper. "It's much more than merely delaying or preventing symptoms."

While the research was carried out in aging mice, it holds immense potential for human brain function.

FTL1: A Key Driver Of Brain Aging

In the study, the researchers tracked shifts in genes and proteins in the hippocampus of mice. The FTL1 protein appeared consistently different between young and old animals.

Compared to young mice, the older mice showed higher levels of FTL1. They also had fewer connections between neurons in the hippocampus and performed worse on cognitive tests.

Increasing FTL1 levels in young mice produced brain changes similar to those seen in older mice. The researchers found that this change occurs because of alterations in the way nerve cells produce FTL1 protein.

In older mice, the nerve cells that produced high amounts of FTL1 developed simplified structures, forming short, single extensions instead of the complex, branching networks seen in healthy cells.

Further experiments showed that in older mice, higher levels of the protein slowed cellular metabolism in the hippocampus -- the part of the brain responsible for learning and memory.

However, when researchers treated these cells with a compound that boosts metabolism, the negative effects were prevented.

Also read: This Unique Diet Slows Brain Aging By Over 2 Years, Study Says

A Promise For Future Brain Aging Therapies

Villeda believes these findings could pave the way for treatments that target FTL1 and counter its effects in the brain.

"We're seeing more opportunities to alleviate the worst consequences of old age," he said. "It's a hopeful time to be working on the biology of aging."

Also read: Exercising Could Make Your Brain Younger, Says Doctor

Here's How To Boost Your Brain

• Simple movements like squats, push-ups or resistance band exercises
• Indulging in mentally challenging activities such as puzzles, reading, strategy games
• Learn new skills like any language, or musical instruments
• Better sleep — about 7-9 hours
• Healthy diet — rich in leafy greens, vegetables, berries, nuts, olive oil, whole grains, fish, beans, poultry
• meditation, deep breathing, or yoga
• Avoid smoking, and drinking alcohol.

Cancer treatment has long been thought to be unsuccessful among people of advanced age, and older adults are often left out of clinical decisions.

While they may face more surgical complications, a new study proved that even people aged over 80 can still safely have surgery and be cured. It showed that the overall health of a patient matters more and that age must not be the only criterion to rule out surgery.

Also Read: Brain Aging: This Protein Is Linked to Memory Loss and Cognitive Decline

The study, published in The Lancet Regional Health – Americas, showed that surgery for lung cancer is safe in elderly patients aged 80 and above, especially when the cancer is in an early stage.

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center in the US found that they can recover like young cancer patients as well as live longer like them.

“As our population ages, more patients over 80 are being diagnosed with early-stage lung cancer, yet they are often not considered for surgery,” said Raja M. Flores, Chair of the Department of Thoracic Surgery at Mount Sinai Health System.

“Our findings show that when patients are carefully selected based on their overall health, not just their age, they can tolerate surgery well and experience excellent long-term outcomes,” he added.

What Did The Study Find?

The study findings are based on a study of 884 patients with early-stage lung cancer, including 114 people who were age 80 or older.

The researchers examined surgical outcomes and quality of life in patients with early-stage non-small cell lung cancer, comparing those aged 80 and older with younger patients.

The results showed that older patients lived just as long as younger patients after surgery. While some older patients had more complications right after surgery, most patients in both groups felt better over time, and their quality of life improved within a year.

The study noted that early detection in older patients may be key. The researchers called for screening guidelines to include patients who are over 80 years old based on these findings.

Also read: Scientists Link Vaping to 2 Types of Cancer; DNA-Damaging Chemicals to Blame

What Is Lung Cancer?

Lung Cancer is one of the most common and serious types of cancer. It is also the leading cause of cancer-related deaths worldwide, with approximately 2.5 million new cases and 1.8 million deaths reported in 2022.

According to the American Cancer Society, lung cancer mainly occurs in older people. Most people diagnosed with lung cancer are 65 or older; a very small number of people diagnosed are younger than 45.

The average age of people when diagnosed is about 70.

It is also the leading cause of cancer death in the US, accounting for about 1 in 5 of all cancer deaths.

In many cases, there are no symptoms; however, one must look out for these:

• a persistent cough
• coughing up blood
• persistent breathlessness
• unexplained tiredness and weight loss
• an ache or pain when breathing or coughing.

Also read: New AIIMS Study To Probe How PM2.5 Is Surging Lung Cancer Risk In India

The two main types of lung cancers are:

Non-small-cell lung cancer (NSCLC): This is the most common form, making up about 80–85% of all cases. NSCLC includes three subtypes:

• Squamous cell carcinoma
• Adenocarcinoma
• Large-cell carcinoma

Cancer is not just a problem of elderly people anymore. In India, there has been an increased number of cases where individuals under the age of 40 are diagnosed with various forms of cancer. Even if there are fewer cases of this medical condition among younger people, this fact does not change the fact that one-fifth of all cancer patients in India are younger than 40 years.

Breast cancer, colorectal cancer, head and neck cancer, as well as blood cancer, are some types of cancer that become more common at a younger age. Among the most alarming statistics, the incidence of colorectal cancer in people aged 30-40 should be mentioned. Moreover, the fact that breast cancer becomes evident nine years earlier in Indian women in comparison with Western women must also be noted.

What Makes This Problem Increase?

There is a wide variety of factors that contribute to this problem. These are the following:

• Lifestyle changes, such as lack of exercise, unhealthy eating habits, being overweight, and stressful situations
• Alcohol and tobacco consumption
• Pollution in the urban environment
• Problems with early diagnosis due to the negligence of patients
• Low screening rates among the young population

Early detection saves lives. Some warning signs to look out for are:

• Sudden and unexplained weight loss
• Endless fatigue
• Digestion issues
• Breast lumps or any swellings anywhere in the body
• Coughing or trouble swallowing persistently

Why Late-stage Diagnosis Is Even More Serious

Not only does it take time to diagnose cancer cases in young patients due to low suspicions, but these cancers also create an additional burden on people during their prime earning period.

How To Combat This Trend

There needs to be a paradigm shift in our understanding of this problem. First of all, we have to understand that cancer affects patients irrespective of their age, and therefore, when you experience some symptoms of cancer, do visit a doctor to get your condition checked out.

The key is maintaining healthy practices like balanced nutrition, exercising, not smoking, and limiting consumption of alcohol.