I’ve always struggled with inconsistent sleep, staying up late and waking up at different times each day. My love for coffee was also on an all-time high with trying all the season specials. But it is only recently, I learned how this irregular sleep pattern and caffeine could increase my risk of heart attack and stroke. Now, I’m prioritizing a consistent sleep schedule and cutting out caffeine after 3 PM to protect my heart.

A new, shocking study shows that irregular sleep patterns can greatly increase the risk of heart attack and stroke. But that's not all: the timing of your caffeine intake could also play a critical role in your cardiovascular health. If you are struggling with inconsistent sleep patterns and regularly sipping on caffeinated beverages late in the day, you may be unknowingly putting yourself at risk for serious heart-related issues.

For most people, sleep is something of a given and we often only consider ourselves as long as we get our required seven to nine hours. However, according to a recent study conducted by researchers at the Children's Hospital of Eastern Ontario, it may not be that long after all. The study, which included more than 72,000 participants, found that people with irregular sleep patterns—those who fall asleep and wake up at vastly different times each day—face a 26% higher risk of experiencing a heart attack or stroke. This increased risk persisted even for those who managed to get enough sleep. The study followed up participants for eight years to track heart events such as heart attacks, strokes, and heart failure. The conclusions were clear: irregular sleep, even if it's sufficient in duration, is a major cardiovascular risk factor.

The researchers found that those whose sleep patterns were highly irregular had a significantly greater chance of life-threatening heart issues. The more erratic your sleep schedule, the greater the risk, regardless of how many hours you sleep. In fact, people with irregular sleep schedules showed worse cardiovascular health outcomes, including higher rates of high blood pressure, elevated stress hormones, and poor blood sugar and cholesterol management.

Senior scientist Dr. Jean-Philippe Chaput said "sleep regularity may be more relevant than sufficient sleep duration in modulating MACE [major adverse cardiovascular event] risk." In the study, it shows that our bodies are comfortable with consistency, and a varied sleep schedule may interfere with other processes that keep us healthy, especially the heart.

Is it Caffeine After 3 PM Causing Sleeplessness?

Another daily habit that may be putting your heart at risk is caffeine consumption after 3 PM. According to Dr. Chaput, the experts emphasize the need for a healthy sleep schedule and avoiding caffeine late in the day. Caffeine can stay in your blood for up to eight hours, and its consumption later in the afternoon can disrupt your sleep cycle.

Consistent, good-quality sleep is necessary for maintaining healthy cardiovascular function, and the disruption of this by late-day caffeine intake exacerbates the risks posed by irregular sleep. When you drink coffee, tea, or other caffeinated beverages too late, the stimulant effect on your nervous system makes it harder to fall asleep at a regular time. This can lead to inconsistent sleep patterns, which, as we have seen, can be harmful to heart health.

Dr Chaput insists that humans need to adopt practices that contribute to regularized sleep habits. This can be attained by establishing a proper sleeping and waking schedule, eliminating afternoon intake of stimulants such as caffeine, and making your body clock coincide with the lifestyle one leads.

How Does Poor Sleep Affect Heart Health?

According to the experts, the disturbance due to irregular sleep patterns impacts more than one physiological process involved in the maintenance of the healthy heart. For example, poor sleep can be associated with increased inflammation of the body, weakened immunity, and altered regulation of blood sugar and cholesterol, all of which contribute to increased blood pressure and weakening endothelial function, both associated with an increased risk for cardiovascular diseases. Sleep also plays a very important role in regulating stress hormones. Poor or disturbed sleep results in increased levels of cortisol, the stress hormone, which increases blood pressure and can have negative impacts on cardiovascular health over time.

Scientists hypothesize that these disturbances trigger a series of negative effects that enhance the risk of developing chronic heart conditions, including hypertension, atherosclerosis, or even heart failure.

Tips to Protect Your Heart and Improve Your Sleep

In order to protect your heart, experts recommend several proactive measures to improve your sleep patterns and lifestyle. First, maintain a regular sleep schedule whereby you go to bed and wake up at the same time every day, including weekends. Consistency will keep your body's internal clock in check.

Along with regulating your sleep, paying attention to your caffeine habits is just as important. To reduce your risk of heart disease and stroke, experts suggest avoiding caffeine after 3 PM. If you’re sensitive to caffeine, this rule becomes even more critical.

In addition, the introduction of stress-reducing activities like yoga or mindfulness can also be beneficial to lower cortisol levels, and therefore both sleep and heart health can improve. A diet rich in antioxidants, healthy fats, and low on processed sugars also helps maintain cholesterol levels and reduce inflammation.

Does Your Sleep Environment Also Has A Role To Play

Apart from the timing of caffeine and your sleep schedule, another very overlooked factor is the quality of your sleep environment. Scientists have long known that the environment in which you sleep has a huge impact on the quality of your rest. Poor quality of sleep, even if your sleep schedule is regular, can cause health risks that are very much the same as those that arise from irregular sleep patterns.

Here’s an additional tip: make sure your bedroom is conducive to restful sleep. This means keeping your room dark, quiet, and cool. A temperature of around 65°F (18°C) is ideal for most people. Consider investing in a comfortable mattress and pillows, and avoid screen time at least 30 minutes before bed to allow your brain to unwind.

Irregular sleep, in association with taking caffeine in late parts of the day, can risk heart attack and stroke, but a simple maintenance of a sleep schedule, the reduction of consumption of afternoon caffeine, and sleep environmental awareness can definitely safeguard one's heart along with total health.

Your sleep is more than just a time for rest; it's a vital component of your long-term health, and maintaining consistency in your sleep habits is one of the best things you can do for your heart.

Before "brain health" became a buzzword, Rudolph E Tanzi started to write the science behind it. Tanzi is a neurology professor at the Harvard, and co-director of the Henry and Allison McCance Center for Brain Health at Massachusetts General Hospital is known for discovering three key Alzheimer's genes. In his 46-year career, he wrote hundreds of journal articles that helped in shaping the modern understanding of neurodegenerative illness.

In 2023, neuroscientist also teamed up with holistic health advocate Deepak Chopra to write Super Brain, a book that pushed against the idea that brain has fixed limits. The belief also sits at the heart of SHIELD, which a lifestyle framework developed by Tanzi to protect long-term brain health. It focuses on six pillars:

• Sleep
• Handling stress
• Interaction with others
• Exercise
• Learning
• Diet

Tanzi now 67, says these principles are not just theoretical, but he credits his own research and daily habits for helping him stay mentally sharp, physically active and deeply engaged in his work.

“I’m doing more work and having more fun and excitement than ever,” he says. “Your world can feel young or stagnant based entirely on the health of your brain. Most people do not realize that.”

Let us look deeper into SHIELD:

Sleep

Tanzi aims for seven to eight hours of quality sleep each night. Sleep, he explains, is not just rest. It is active maintenance for the brain.

During deep sleep, the brain clears out toxins, including amyloid proteins that are linked to Alzheimer’s disease years before symptoms appear. Each deep sleep cycle works like a rinse for the brain.

Rather than following a fixed bedtime, Tanzi plans backward from his wake-up time to ensure at least seven hours of sleep. An hour before bed, screens go off and phone scrolling stops. If sleep falls short, he recommends short power naps, even brief ones.

Handling stress

Chronic stress is one of the biggest threats to brain health. It raises cortisol levels, which Tanzi describes as toxic to the brain over time.

He believes modern life has amplified stress through constant notifications, emails and social media. His primary tool to counter this is meditation, especially practices that quiet the constant internal chatter many people experience.

Tanzi suggests closing your eyes periodically during the day and focusing on images rather than words. Let thoughts come and go without turning them into sentences. He also warns against living mentally in the past or worrying excessively about the future instead of staying present.

Reducing this internal noise, he says, boosts creativity, intuition and mental clarity.

Interaction with friends

Social connection matters more than many people realize. Loneliness has been linked to a higher risk of cognitive decline.

The key, Tanzi says, is interacting with people you genuinely enjoy. Stressful social interactions do not count. Even regular texting or phone calls can help.

Because many of his friends live far away, Tanzi stays connected through small, intentional check-ins with different friend groups each day. Used this way, social media can actually support brain health instead of draining it.

Read: Neurologist Shares 10 Eating Habits For A Longer, Healthier Life

Exercise

Regular movement improves blood flow to the brain and helps form new nerve cells, particularly in areas affected early by Alzheimer’s disease. Exercise also releases hormones that help break down harmful amyloid buildup.

Tanzi cycles on a stationary bike for 30 minutes every other day and walks on alternate days. He points to research showing that even modest increases in daily steps can meaningfully reduce dementia risk.

Learning new things

Learning builds new synapses, the connections that store memories and support thinking. When these connections weaken, cognition suffers.

As people age, Tanzi says they often become less adventurous and rely on the same mental patterns. That stagnation harms the brain.

To counter this, he constantly learns new music on the keyboard, writes his own compositions, reads widely and watches documentaries. New experiences keep the brain flexible and resilient.

Diet

Diet plays a central role in brain health, largely through the gut microbiome. When gut bacteria are balanced, they produce compounds that reduce inflammation and help clear amyloid from the brain.

Tanzi follows a Mediterranean-style diet rich in fruits, vegetables, olive oil, nuts and seeds. He is mostly vegan but not rigid. His snacks tend to be crunchy whole foods that gut bacteria thrive on.

He is also increasingly focused on environmental factors that affect the brain. His upcoming book will explore what he calls the “killer P’s,” including plastics, pollution, periodontal bacteria and processed foods, and how they quietly shape long-term brain health.

Deadly Nipah Virus Outbreak: Nipah virus outbreak reported in West Bengal, India started with the cases of two nurses, one of whom is in "critical condition". Nearly 100 people are quarantined, and India's Ministry of Health shared precautions to prevent Nipah virus infection in a post on X.

However, how did it all start?

Nipah Virus: The Evolution And Where It All Began

The original infection was first identified in September 1998 in Perak, Malaysia, which was followed by second and third clusters in the state of Negri Sembilan, notes a 2021 study that tracks the evolution of the virus. The cases were prominent in adult men who were in contact with swine. By March 1999, a cluster of 11 similar cases were identified in Singapore, mostly common in slaughterhouse workers, who were in contact with pigs imported from Malaysia. This is how the virus started to become global. While people there were isolated, the outbreak in Malaysia continued to spread. This led to restrictions on swine imports to Singapore, followed by nationwide testing among pigs in Malaysia, and ultimately mass culling of over one million pigs from any farm in Malaysia with a confirmed infection.

Read: Nipah Virus Outbreak India: How Contagious Is It And Who Is Most At Risk?

Then appeared a new, distinct strain of Nipah virus with infection which was characterized largely by severe respiratory symptoms. In 2000-2001, Bangladesh and India were affected. Epidemiological studies revealed clustering around household members and hospital contacts without any clear animal exposure. This raised suspicion for human to human transmission.

Nipah Virus In Bats: How Did Scientists Know?

When Nipah virus (NiV) was first identified, scientists noted that the closely related Hendra virus persisted in fruit bats of the Pteropus genus, raising early suspicions that these bats could also be the natural reservoir for NiV. Later research confirmed the presence of NiV genetic material and neutralising antibodies in urine, saliva, blood and various organs of several Pteropus bat species across Asia, including in countries with no recorded human cases.

This raised doubts, and it was later revealed that due to the consumption of raw date palm juice, the infection developed. This is because bats also are carrier of the virus and they may bite into raw fruits or lick them, and consuming juice from such fruits could spread the infection. This was a common practice in Bangladesh and much of South Asia.

Read: Nipah Virus Outbreak in India: 100 People Quarantined, Doctor Issues Food Warnings

Studies examining human exposure patterns found a strong link between NiV infection and the consumption of raw date palm sap. The sap, typically harvested between December and February, is often contaminated by bats that feed on it, leaving behind saliva and urine. In Bangladesh, this route has been identified as the main pathway of transmission from bats to humans, although the possibility of additional human-to-human spread remains.

Nipah Virus Went Global

In 2014, a serious outbreak of illness hit two villages in southern Philippines, with people developing brain infections, meningitis and flu-like symptoms. Tests later confirmed Nipah virus as the cause. Among those who developed acute brain infection, the death rate was extremely high at 82 percent. While some infections spread from person to person, this was the first outbreak linked to the slaughter of horses and the consumption of horse meat. Around the same time, several horses and other domestic animals that had eaten horse meat also fell sick and died.

In 2018, another outbreak occurred in Kerala, India, where 23 confirmed and suspected cases were reported. The virus spread across three hospitals, with both primary and secondary infections traced back to one initial patient. Samples collected from the patient’s home and workplaces, including pets and partially eaten fruits dropped by bats, all tested negative for the virus, and the exact source of the infection could not be identified.

Read: Doctor Debunks Five Myths Around Nipah Virus

Nipah Virus Outbreak In India's West Bengal

Currently, two nurses, a doctor, hospital staff and some patients have reported to be infected by the virus. A survey conducted on bats in West Bengal found no active Nipah virus infection. Though there were antibodies detected in one specimen, which indicated prior exposure. This was confirmed by a senior state forest department official. The survey was conducted amid the identification of two confirmed Nipah virus cases.

To conduct the survey, nine bats near Kuberpur on the Kolkata-Barasat Road in Madhyamgram were tested using RT-PCR. All samples were negative, however, one bat, tested positive for antibodies. However, it only suggested prior infection, meaning there was no current risk of transmission.

Read: Nipah Virus Outbreak In India: How Is The Virus Being Contained?

The survey was conducted by the state forest department in collaboration with scientists form Pune-based National Institute of Virology. "The findings are reassuring, but caution is warranted. Surveillance and prevent measures will continue until we are fully assured that there is no risk," confirmed a senior official of the West Bengal Health Department.

Nipah Virus: What Is It And What Are The Symptoms?

As per the World Health Organization (WHO), Nipah virus infection is a zoonotic illness that is transmitted to people from animals, and can also be transmitted through contaminated food or directly from person to person.

In infected people, it causes a range of illnesses from asymptomatic (subclinical) infection to acute respiratory illness and fatal encephalitis. The virus can also cause severe disease in animals such as pigs, resulting in significant economic losses for farmers.

Although Nipah virus has caused only a few known outbreaks in Asia, it infects a wide range of animals and causes severe disease and death in people.

Nipah Virus Symptoms

• Fever
• Headache
• Breathing difficulties
• Cough and sore throat
• Diarrhea
• Vomiting
• Muscle pain and severe weakness

Your weight not only affects your heart health but also your brain health. A recent study published in the Journal of Clinical Endocrinology & Metabolism has revealed a powerful connection between your body weight, heart and brain.

After studying over 500,000 people, scientists discovered that having a high Body Mass Index (BMI) can nearly double your chances of developing brain-related illnesses later in life, which confirms that being overweight and having high blood pressure are not just general health concerns, they are direct causes of dementia.

How Does Your Weight Affect Brain Health?

The study focused heavily on vascular dementia, a specific type of memory loss that occurs when the brain is damaged because of a lack of blood flow.

Think of your blood vessels like a system of pipes. If those pipes are narrowed or blocked due to weight-related issues, the "engine" (your brain) doesn't get the fuel it needs. Over time, this lack of oxygen and nutrients leads to permanent brain damage and the loss of memory and thinking skills.

Researchers found that high blood pressure, often caused by carrying extra weight, is the main "middleman" in this process. Blood pressure is measured with two numbers, and both play a part in brain health:

Systolic

This is the pressure when your heart beats. It accounts for about 18 percent of the link between obesity and dementia.

Diastolic

This is the pressure when your heart rests between beats. It accounts for about 25 percent of the link. When these numbers stay high, they constantly "batter" the delicate vessels in the brain, causing them to weaken or clog.

How Weight Affects the Brain

Beyond just blood flow, a high BMI impacts the brain in several other ways:

Increased Inflammation

Obesity often causes the body to be in a constant state of "alarm" or inflammation. This can irritate the immune system and eventually damage brain cells.

Metabolism Issues

When the body struggles to process energy and food properly, it changes how the brain uses energy, which can lead to cognitive decline.

Heart Strain

A heart that has to work harder to pump blood through a larger body eventually becomes less efficient at sending blood all the way up to the brain. Your heart essentially has to do twice as much work as it would at a lower weight.

Can Preventing Obesity Help Dementia?

The most encouraging takeaway from this study is that dementia isn't always a matter of bad luck or "old age." Researchers call this an unexploited opportunity.

By managing your weight and blood pressure early in life, through a healthy diet, consistent exercise, and good sleep, you are essentially "dementia-proofing" your brain. The researchers suggested that intervening early, possibly even with weight-loss medications before symptoms start, could be a key strategy for protecting brain health in the future.

How Much Does Obesity Affect Worldwide?

According to the World Health Organization, one in eight people in the world are living with obesity. In 2022, about 2.5 billion adults were overweight. Causes of it vary, from things like diseases or chronic conditions, to the kind of food that is available to consume.