Irregular Sleep, Drinking Caffeine After 3PM Could Raise Your Risk Of Heart Attack And Stroke
I’ve always struggled with inconsistent sleep, staying up late and waking up at different times each day. My love for coffee was also on an all-time high with trying all the season specials. But it is only recently, I learned how this irregular sleep pattern and caffeine could increase my risk of heart attack and stroke. Now, I’m prioritizing a consistent sleep schedule and cutting out caffeine after 3 PM to protect my heart.
A new, shocking study shows that irregular sleep patterns can greatly increase the risk of heart attack and stroke. But that's not all: the timing of your caffeine intake could also play a critical role in your cardiovascular health. If you are struggling with inconsistent sleep patterns and regularly sipping on caffeinated beverages late in the day, you may be unknowingly putting yourself at risk for serious heart-related issues.
For most people, sleep is something of a given and we often only consider ourselves as long as we get our required seven to nine hours. However, according to a recent study conducted by researchers at the Children's Hospital of Eastern Ontario, it may not be that long after all. The study, which included more than 72,000 participants, found that people with irregular sleep patterns—those who fall asleep and wake up at vastly different times each day—face a 26% higher risk of experiencing a heart attack or stroke. This increased risk persisted even for those who managed to get enough sleep. The study followed up participants for eight years to track heart events such as heart attacks, strokes, and heart failure. The conclusions were clear: irregular sleep, even if it's sufficient in duration, is a major cardiovascular risk factor.
The researchers found that those whose sleep patterns were highly irregular had a significantly greater chance of life-threatening heart issues. The more erratic your sleep schedule, the greater the risk, regardless of how many hours you sleep. In fact, people with irregular sleep schedules showed worse cardiovascular health outcomes, including higher rates of high blood pressure, elevated stress hormones, and poor blood sugar and cholesterol management.
Senior scientist Dr. Jean-Philippe Chaput said "sleep regularity may be more relevant than sufficient sleep duration in modulating MACE [major adverse cardiovascular event] risk." In the study, it shows that our bodies are comfortable with consistency, and a varied sleep schedule may interfere with other processes that keep us healthy, especially the heart.
Another daily habit that may be putting your heart at risk is caffeine consumption after 3 PM. According to Dr. Chaput, the experts emphasize the need for a healthy sleep schedule and avoiding caffeine late in the day. Caffeine can stay in your blood for up to eight hours, and its consumption later in the afternoon can disrupt your sleep cycle.
Consistent, good-quality sleep is necessary for maintaining healthy cardiovascular function, and the disruption of this by late-day caffeine intake exacerbates the risks posed by irregular sleep. When you drink coffee, tea, or other caffeinated beverages too late, the stimulant effect on your nervous system makes it harder to fall asleep at a regular time. This can lead to inconsistent sleep patterns, which, as we have seen, can be harmful to heart health.
Dr Chaput insists that humans need to adopt practices that contribute to regularized sleep habits. This can be attained by establishing a proper sleeping and waking schedule, eliminating afternoon intake of stimulants such as caffeine, and making your body clock coincide with the lifestyle one leads.
According to the experts, the disturbance due to irregular sleep patterns impacts more than one physiological process involved in the maintenance of the healthy heart. For example, poor sleep can be associated with increased inflammation of the body, weakened immunity, and altered regulation of blood sugar and cholesterol, all of which contribute to increased blood pressure and weakening endothelial function, both associated with an increased risk for cardiovascular diseases. Sleep also plays a very important role in regulating stress hormones. Poor or disturbed sleep results in increased levels of cortisol, the stress hormone, which increases blood pressure and can have negative impacts on cardiovascular health over time.
Scientists hypothesize that these disturbances trigger a series of negative effects that enhance the risk of developing chronic heart conditions, including hypertension, atherosclerosis, or even heart failure.
In order to protect your heart, experts recommend several proactive measures to improve your sleep patterns and lifestyle. First, maintain a regular sleep schedule whereby you go to bed and wake up at the same time every day, including weekends. Consistency will keep your body's internal clock in check.
Along with regulating your sleep, paying attention to your caffeine habits is just as important. To reduce your risk of heart disease and stroke, experts suggest avoiding caffeine after 3 PM. If you’re sensitive to caffeine, this rule becomes even more critical.
In addition, the introduction of stress-reducing activities like yoga or mindfulness can also be beneficial to lower cortisol levels, and therefore both sleep and heart health can improve. A diet rich in antioxidants, healthy fats, and low on processed sugars also helps maintain cholesterol levels and reduce inflammation.
Apart from the timing of caffeine and your sleep schedule, another very overlooked factor is the quality of your sleep environment. Scientists have long known that the environment in which you sleep has a huge impact on the quality of your rest. Poor quality of sleep, even if your sleep schedule is regular, can cause health risks that are very much the same as those that arise from irregular sleep patterns.
Here’s an additional tip: make sure your bedroom is conducive to restful sleep. This means keeping your room dark, quiet, and cool. A temperature of around 65°F (18°C) is ideal for most people. Consider investing in a comfortable mattress and pillows, and avoid screen time at least 30 minutes before bed to allow your brain to unwind.
Irregular sleep, in association with taking caffeine in late parts of the day, can risk heart attack and stroke, but a simple maintenance of a sleep schedule, the reduction of consumption of afternoon caffeine, and sleep environmental awareness can definitely safeguard one's heart along with total health.
Your sleep is more than just a time for rest; it's a vital component of your long-term health, and maintaining consistency in your sleep habits is one of the best things you can do for your heart.
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A new Lancet study titled Burden of MASLD and liver fibrosis: evidence from the Phenome India cohort published in The Lancet Regional Health - South Asia found that nearly four in 10 Indian adults have fatty liver or what scientifically is known as the metabolic dysfunction-associated steatotic liver disease (MASLD), formerly non as NAFLD or non-alcoholic fatty liver disease.
The study also highlights a more worrying condition that a sizeable proportion of the Indian population already show signs of liver fibrosis. This is an early scarring process that could lead to cirrhosis or liver cancer if left unchecked.
The study analyzed data from more than 7,700 adults across 27 cities in India. The study found that 38.9 per cent of participants had MASLD. The authors also noted that this figure is similar to the global estimates, however, is deeply concerning for India's population and size of the country, including the ever-rising burden of diabetes and obesity.
The study also found that 6.3 per cent of people who live with MASLD had significant liver fibrosis, as compared to 1.7 per cent of those without fatty liver.
Read: Indians Are At Most Risk Of Having Fatty Liver Disease, According To Doctor
The study also found that 2.4 per cent of the entire population analyzed showed evidence of significant fibrosis. Why is this concerning? Fibrosis is a strong predicator of future complications. With the advancement of scarring, liver failure, cirrhosis, and liver caser risk also rises.
The study found that people with obesity, diabetes, and central or abdominal fat were more likely to have MASLD. Obesity also was seen as the strongest risk factor, with likelihood rising steeply from overweight to severe obesity.
Another factor was also age. Liver fibrosis was seen in adults over the age of 60 years and in people with diabetes, among whom nearly one in ten showed fibrotic changes.
The study also showed that there was a presence of "Lean MASLD", which means it could also happen in people who are not overweight and have a normal body mass index. This is often linked to insulin resistance and visceral fat, which is the fat around internal organs. This tend to accumulate abdominal fat even at lower body weights.
As per the authors of the study, MASLD is highly modifiable, especially at early stages. There are evidence that show that weight loss reduces liver fat and inflammation. Regular physical activity also improves insulin sensitivity, along with balanced diet. The diet must be consumed without or with very low sugar and ultra-processed food, which helps in control of diabetes and cholesterol and slows down disease progression.
Authors also noted that people should get their fatty liver disease scanned regularly. Especially because MASLD is common among people with obesity and diabetes. There are many non-aggressive tools that could also detect fibrosis early.
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When Robert F Kennedy Jr took charge of America's health as the Secretary of Health and Human Services in 2025, the promise was sweeping. It included: restoring trust, clean up the food supply, rethink vaccine, though he clearly did state during debates that he is not against it, and reshape a system he said had failed many families for decades.
On February 13, 2025, the day he was sworn in, the US President Trump said, "Our public health system has squandered the trust of our citizens. They don’t trust us. They don’t trust anybody, frankly. They’ve gone through hell.” Trump promised that Kennedy would "lead out campaign of historic reforms and restore faith in American health care". A year from now, Health and Me analyzes those MAHA (Make America Healthy Again) promises.
he Make America Healthy Again (MAHA) movement produced policy changes, lawsuits, agency upheavals and intense public debate, but also falling trust in public health agencies and uncertain long-term impact.
Read: I'm Not Afraid Of Germs, I Snorted Cocaine Off Toilet Seats, Says US Secretary of Health, RFK Jr
Kennedy’s campaign had centered on a simple message: American children are sicker because their food is broken. As health secretary, he created a MAHA Commission to investigate children’s health.
Its first report blamed rising chronic illness partly on diet and raised alarms about herbicides like glyphosate and atrazine being found in children and pregnant women. Farmers and food companies revolted, lobbying lawmakers in agricultural states.
The backlash worked. By the commission’s follow-up report in September, pesticide references had vanished entirely, a clear sign of political limits.
Read: Under RFK Jr's MAHA, More Food Dyes Are Getting Banned In US
Still, Kennedy pushed nutrition policy aggressively. New dietary guidelines promoted whole milk, red meat and less ultraprocessed food. Supporters applauded a focus on real food, and food companies even pledged to remove artificial dyes by 2027.
But critics said the results were partial at best. Nutrition expert Dr. Marion Nestle told CNN that despite momentum, progress stalled: “One big disappointment is the lack of progress on removing industrial and agricultural chemicals from the food supply.”
No area defined Kennedy’s first year more than vaccines.
He fired members of a CDC advisory panel, replaced them, sometimes with skeptics, and cut the list of routinely recommended childhood vaccines from 17 to 11, aligning the U.S. closer to Denmark’s schedule. Several vaccines, including flu and hepatitis A, were removed from routine recommendations.
Supporters framed it as restoring parental choice. Critics called it dangerous.
Read: RFK Jr. Removes Entire CDC Vaccine Advisory Committee
Yale public health expert Dr. Jason Schwartz told CNN the consequences could be severe: “Today, the federal government’s public health agencies and leaders represent the greatest threat to efforts to prevent measles… a scenario that would have been inconceivable a few years ago.”
Outbreaks soon followed, measles deaths returned after a decade without them. And polling showed trust in the CDC falling from 59% to 47%.
Kennedy argued declining trust started before him and that transparency would fix it. But many scientists disagreed. Infectious disease expert Dr. Michael Osterholm told CNN the new approach replaced evidence with politics: “Decisions are being made based on ideology.”
Within days of Kennedy’s swearing-in, thousands of employees across CDC, FDA and NIH were fired in a sweeping reorganization aimed at shrinking the department by about 20,000 workers.
Leadership churn followed. A CDC director was ousted, nominees withdrawn, senior officials resigned, and a major shooting at CDC headquarters, carried out by a man angry about vaccines, intensified tensions. Hundreds of staff later urged Kennedy to stop spreading misinformation.
Researchers warned expertise was disappearing. Johns Hopkins epidemiologist Dr. Caitlin Rivers told CNN local health departments depend on federal specialists: "A lot of those people aren’t there anymore.”
Read: How Susan Monarez's Appoint As CDC Director Can Change US Health Sector?
Meanwhile, Kennedy struggled with forces outside his control. According to Politico reporting, his attempts to regulate agricultural chemicals faltered because authority belonged to the Environmental Protection Agency and Republican lawmakers pushed back heavily.
At the Food and Drug Administration, Kennedy’s agenda pulled in two directions.
On one hand, the administration sought cheaper drugs and faster access. On the other, it raised evidence standards and blocked or slowed approvals, including scrutiny of a muscular dystrophy therapy after patient deaths.
Also Read: Top U.S. Medical Associations Ousted from CDC Vaccine Workgroups in Sudden Shake-Up
Even allies noticed contradictions. The agency alternated between right-to-try deregulation and skepticism toward pharmaceutical safety. The result: uncertainty for both industry and patients.
Trump promised Kennedy would restore faith in public health. Instead, surveys show trust in both health agencies and Kennedy himself fell.
Read: What Is 'Make America Healthy Again' All About?
Nutrition reforms gained modest support. Drug price messaging resonated politically. But experts repeatedly emphasized the same conclusion: vaccine policy overshadowed everything else.
Nutrition policy expert Dr. Jerold Mande told CNN messaging that authorities had lied for decades may have backfired:
“Most people will take from that: we shouldn’t trust anybody."
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The World Health Organization (WHO) is urging countries to accelerate efforts to provide proper eye care, as a new Lancet Global Health study shows that nearly half of all people across the world facing cataract‑related blindness still need access to surgery.
As of now, statistical models predict that the global coverage of cataract surgery is set to increase by about 8.4 percent this decade. However, progress needs to accelerate sharply to meet the World Health Assembly target of a 30 percent increase by 2030.
Devora Kestel, Director, WHO Department of Noncommunicable Diseases and Mental Health: "Cataract surgery is one of the most powerful tools we have to restore vision and transform lives. When people regain their sight, they regain independence, dignity, and opportunity."
The literature review, which analyzed reports from 68 country estimates for 2023 and 2024 shows that the African Region faces the greatest gap, with three in four people who need cataract surgery remaining untreated.
Additionally, women are disproportionately affected across all regions, consistently experiencing lower access to care than men.
Researchers noted that the gap in access to surgery was mostly due to long-standing structural barriers, including shortages and unequal distribution of trained eye-care professionals, high out-of-pocket costs, long waiting times and limited awareness or demand for surgery, even where services exist.
In addition, while age is the primary risk factor for cataract, other contributors such as prolonged UV-B exposure, tobacco use, corticosteroid use and diabetes can accelerate its development.
Most cataracts develop slowly and don't disturb eyesight early on. But with time, cataracts will eventually affect vision. Symptoms of cataracts include:
At first, stronger lighting and eyeglasses can help deal with cataracts. But if impaired vision affects usual activities, cataract surgery might be needed. Surgery is generally a safe, effective procedure.
The doctors confirmed that most cases now appear with patients who have allergies, dryness, burning sensations and excessive watering in the eyes. The pollution is not only affecting children, but adults are also equally impacted.
Dr Ikeda Lal, Senior Cornea, Cataract and Refractive Surgery Specialist at Delhi Eye Centre and Sir Ganga Ram Hospital told PTI: "Every year after Diwali, we brace for a rise in eye complaints. The number of patients complaining of itching, redness, and irritation has gone up by almost 50-60 per cent."
A study from 2022 published in the International Journal of Environmental Research and Public Health notes the adverse effects of air pollution on the eyes. Air pollution is a mix of complex gas-phase pollutants and particles that are disbursed into the atmosphere and are harmful.
It comprises:
Air pollution is known to cause cardiovascular disorders, respiratory tract problems, ocular disease, neurologic disease, cancer, and even death, notes the study.
In terms of its impact on the eyes, the pollutants usually work as irritants, which can cause inflammation and irritation in the eyes.
The cornea is the most sensitive structure in the human body due to its innervation in the ocular surface, which makes it extremely sensitive to environmental agents. The pollutants could thus cause conjunctivitis, which could become a frequent problem.
In addition to that, household pollution could also produce volatile organic compounds; for instance, formaldehyde could cause DNA damage in animal cells, and its carcinogenicity has been assessed by many studies too.
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