Irregular Sleep, Drinking Caffeine After 3PM Could Raise Your Risk Of Heart Attack And Stroke
I’ve always struggled with inconsistent sleep, staying up late and waking up at different times each day. My love for coffee was also on an all-time high with trying all the season specials. But it is only recently, I learned how this irregular sleep pattern and caffeine could increase my risk of heart attack and stroke. Now, I’m prioritizing a consistent sleep schedule and cutting out caffeine after 3 PM to protect my heart.
A new, shocking study shows that irregular sleep patterns can greatly increase the risk of heart attack and stroke. But that's not all: the timing of your caffeine intake could also play a critical role in your cardiovascular health. If you are struggling with inconsistent sleep patterns and regularly sipping on caffeinated beverages late in the day, you may be unknowingly putting yourself at risk for serious heart-related issues.
For most people, sleep is something of a given and we often only consider ourselves as long as we get our required seven to nine hours. However, according to a recent study conducted by researchers at the Children's Hospital of Eastern Ontario, it may not be that long after all. The study, which included more than 72,000 participants, found that people with irregular sleep patterns—those who fall asleep and wake up at vastly different times each day—face a 26% higher risk of experiencing a heart attack or stroke. This increased risk persisted even for those who managed to get enough sleep. The study followed up participants for eight years to track heart events such as heart attacks, strokes, and heart failure. The conclusions were clear: irregular sleep, even if it's sufficient in duration, is a major cardiovascular risk factor.
The researchers found that those whose sleep patterns were highly irregular had a significantly greater chance of life-threatening heart issues. The more erratic your sleep schedule, the greater the risk, regardless of how many hours you sleep. In fact, people with irregular sleep schedules showed worse cardiovascular health outcomes, including higher rates of high blood pressure, elevated stress hormones, and poor blood sugar and cholesterol management.
Senior scientist Dr. Jean-Philippe Chaput said "sleep regularity may be more relevant than sufficient sleep duration in modulating MACE [major adverse cardiovascular event] risk." In the study, it shows that our bodies are comfortable with consistency, and a varied sleep schedule may interfere with other processes that keep us healthy, especially the heart.
Another daily habit that may be putting your heart at risk is caffeine consumption after 3 PM. According to Dr. Chaput, the experts emphasize the need for a healthy sleep schedule and avoiding caffeine late in the day. Caffeine can stay in your blood for up to eight hours, and its consumption later in the afternoon can disrupt your sleep cycle.
Consistent, good-quality sleep is necessary for maintaining healthy cardiovascular function, and the disruption of this by late-day caffeine intake exacerbates the risks posed by irregular sleep. When you drink coffee, tea, or other caffeinated beverages too late, the stimulant effect on your nervous system makes it harder to fall asleep at a regular time. This can lead to inconsistent sleep patterns, which, as we have seen, can be harmful to heart health.
Dr Chaput insists that humans need to adopt practices that contribute to regularized sleep habits. This can be attained by establishing a proper sleeping and waking schedule, eliminating afternoon intake of stimulants such as caffeine, and making your body clock coincide with the lifestyle one leads.
According to the experts, the disturbance due to irregular sleep patterns impacts more than one physiological process involved in the maintenance of the healthy heart. For example, poor sleep can be associated with increased inflammation of the body, weakened immunity, and altered regulation of blood sugar and cholesterol, all of which contribute to increased blood pressure and weakening endothelial function, both associated with an increased risk for cardiovascular diseases. Sleep also plays a very important role in regulating stress hormones. Poor or disturbed sleep results in increased levels of cortisol, the stress hormone, which increases blood pressure and can have negative impacts on cardiovascular health over time.
Scientists hypothesize that these disturbances trigger a series of negative effects that enhance the risk of developing chronic heart conditions, including hypertension, atherosclerosis, or even heart failure.
In order to protect your heart, experts recommend several proactive measures to improve your sleep patterns and lifestyle. First, maintain a regular sleep schedule whereby you go to bed and wake up at the same time every day, including weekends. Consistency will keep your body's internal clock in check.
Along with regulating your sleep, paying attention to your caffeine habits is just as important. To reduce your risk of heart disease and stroke, experts suggest avoiding caffeine after 3 PM. If you’re sensitive to caffeine, this rule becomes even more critical.
In addition, the introduction of stress-reducing activities like yoga or mindfulness can also be beneficial to lower cortisol levels, and therefore both sleep and heart health can improve. A diet rich in antioxidants, healthy fats, and low on processed sugars also helps maintain cholesterol levels and reduce inflammation.
Apart from the timing of caffeine and your sleep schedule, another very overlooked factor is the quality of your sleep environment. Scientists have long known that the environment in which you sleep has a huge impact on the quality of your rest. Poor quality of sleep, even if your sleep schedule is regular, can cause health risks that are very much the same as those that arise from irregular sleep patterns.
Here’s an additional tip: make sure your bedroom is conducive to restful sleep. This means keeping your room dark, quiet, and cool. A temperature of around 65°F (18°C) is ideal for most people. Consider investing in a comfortable mattress and pillows, and avoid screen time at least 30 minutes before bed to allow your brain to unwind.
Irregular sleep, in association with taking caffeine in late parts of the day, can risk heart attack and stroke, but a simple maintenance of a sleep schedule, the reduction of consumption of afternoon caffeine, and sleep environmental awareness can definitely safeguard one's heart along with total health.
Your sleep is more than just a time for rest; it's a vital component of your long-term health, and maintaining consistency in your sleep habits is one of the best things you can do for your heart.
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Indian Actress Dipika Kakkar, battling liver cancer, underwent another surgery last month for a 1.3 cm cyst that reappeared.
Best known for her role as Simar Bhardwaj in the hit TV show Sasural Simar Ka, Dipika underwent a major tumour-removal surgery in June 2025. She also undertook chemotherapy
In her latest vlog, Dipika shared that the unexpected recurrence has left her feeling anxious and overwhelmed as doctors evaluate the next course of treatment.
"The recurrence that happened with the 1.3 cm cyst has shaken me. I am a little scared now that it shouldn't happen again. I have started dieting, but I feel anxious," she said.
HealthandMe spoke to health experts to understand why cysts recur in liver cancer patients and how it's important to keep monitoring them.
According to health experts, a biannual liver scan is imperative, and it can detect signs of cysts.
“Simple cysts less than 2-3 Cm can be observed with repeat scans every 6 months to 1 year. Suspicious or malignant cysts need surgical resection and oncological treatment based on the histopathology and patient condition,” Dr Manjunath NML, Sr Consultant, Surgical Oncology and Robotic Surgeon, HCG Cancer Hospital, K R Road, Bengaluru.
Liver cysts are like bags that are filled with fluid. They are usually not cancer. Most people who have liver cysts do not get cancer.
However, just because one has a cyst, it does not mean it's cancer.
“Cysts in the liver are typically harmless and unrelated to liver cancer. However, unusual types of cysts may suggest malignant changes that need further examination, particularly among risk groups,” Dr. Govind Nandakumar, Consultant – Gastrointestinal Surgery, Manipal Hospitals Hebbal, told HealthandMe.
The experts noted that cases of recurring cysts related to liver cancer are uncommon. But they occur because of
Also read: 1 In 4 Diabetic Patients in India Suffer from Liver Fibrosis, Finds Lancet Study
Many liver cysts do not cause any problems in the early stages. That is why regular check-ups with a doctor are important. If a cyst grows or becomes problematic, symptoms may begin to appear. These can include
Recurrent cysts can be effectively managed and treated over time. The recurrence does not necessarily imply the progression of the condition itself; however, more tests may be required to determine whether cysts are malignant or benign.
“Cysts with thick walls, septations inside, and solid components in them are more likely to be cancerous. If the cysts are large, they cause symptoms like pain, distension, and obstruction of the bowel or biliary tract,” Dr Manjunath said.
The experts explained that diagnosis can be achieved by scans like ultrasonography, Computerized Tomography CT or Magnetic Resonance Imaging (MRI). Suspicious cysts must be checked via biopsy to confirm malignancy.
While suspicious or malignant cysts require surgical resection and oncological treatment, symptomatic cysts, even if benign, may also require removal.
However, if a liver cyst is detected without suspicious features and is asymptomatic, it usually does not require any intervention, Dr. Manjunath noted.
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What if the body whispers long before it screams? For many living with Parkinson’s disease, the earliest signs are not the tremors, but quieter changes, such as a diminished sense of smell, disrupted sleep, or gut problems. The challenge is that we are conditioned to look for the disease only once it becomes visible.
Parkinson’s disease, commonly referred to as a movement disorder, progresses slowly due to the destruction of the nerve cells in the brain.
To understand Parkinson’s disease, think of the brain as a command center where certain nerve cells produce dopamine, a chemical messenger that helps coordinate smooth movement. As these dopamine-producing cells gradually deteriorate, the brain’s signalling system gets disturbed, leading to slower movements, mistaken for normal ageing.
The majority of patients experience subtle early signs much before diagnosis, including a reduced sense of smell, sleep disturbances like insomnia, and persistent digestive problems like constipation. In these cases, timely intervention can reduce movement disability by roughly 40 percent.
Also read: Blame This Brain Region Behind Laughing, Coughing For Your Hypertension
Conventional treatment focuses on medications that boost dopamine levels, but over time, their effectiveness may decline. When drugs are no longer sufficient, doctors may recommend Deep Brain Stimulation (DBS), a surgical approach that works like a pacemaker for the brain and uses chest-connected electrodes to reset faulty signals causing stiffness and tremors.
Unlike fixed traditional stimulation, the advanced Adaptive DBS (aDBS) listens to brain signals in real-time to adjust therapy automatically. Its single threshold mode reacts instantly, boosting stimulation the moment brain signals hit a specific limit and turns it off just as fast once they improve.
Alternatively, its double threshold mode keeps stimulation steady within the safe zone," making only gradual tweaks if signals cross upper or lower limits. This smart system mimics the body’s natural rhythm to provide fluid symptom control while preventing overstimulation, ultimately helping you reclaim more "good" time and independence.
There is no single ‘Parkinson’s diet,’ but certain food choices can help manage symptoms and overall well-being. A balanced diet rich in fruits, vegetables, and whole grains supports general health and may help reduce inflammation.
Plant-based flavonoids, present in berries, citrus fruits, and broccoli, which have antioxidant effects, can help protect brain cells from damage. Drinking enough water can support digestion and prevent dehydration.
Ultimately, small, consistent dietary choices, combined with medical guidance, can make a meaningful difference in managing symptoms.
Parkinson’s disease is a journey, and the earlier the signs are recognized, the better the condition can be managed. If you or a loved one is experiencing persistent changes in sleep, smell, or movement, do not wait for the symptoms to become overwhelming. Consulting a neurologist is the first step toward taking back control of your health.
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While salt, cholesterol, and obesity are major factors driving high blood pressure, a recent study suggests they may not be the only causes.
Researchers from Brazil and New Zealand have identified a brain region that may increase the risk of hypertension. The study, published in the journal Circulation Research, showed that the brain region called the lateral parafacial region is the culprit.
The lateral parafacial region sits in the brainstem – the oldest part of the brain – which controls automatic functions such as digestion, breathing, and heart rate.
“The lateral parafacial region is recruited into action, causing us to exhale during a laugh, exercise, or coughing,” said lead researcher Professor Julian Paton, from the Centre for Heart Research at Waipapa Taumata Rau, University of Auckland.
“These exhalations are what we call ‘forced’ and are driven by our powerful abdominal muscles. In contrast, a normal exhalation does not need these muscles to contract; it happens because the lungs are elastic,” Paton added.
Paton and the team found that the lateral parafacial region also connects to nerves that tighten blood vessels -- a mechanism that raises blood pressure.
“We’ve unearthed a new region of the brain that is causing high blood pressure. Yes, the brain is to blame for hypertension!” Paton said.
“We discovered that, in conditions of high blood pressure, the lateral parafacial region is activated and, when our team inactivated this region, blood pressure fell to normal levels.”
The team explained that this means changes in breathing patterns – especially those involving strong abdominal muscle contractions – can trigger high blood pressure. Thus, any diagnosis of abdominal breathing in patients with high blood pressure may reveal the cause and hence direct appropriate treatment.
The next question was whether the brainstem region could be treated with a medication.
“Targeting the brain with drugs is tricky because they act on the entire brain and not a selected region such as the parafacial nucleus,” Paton said.
The researchers then discovered that this region is activated by signals from outside the brain – from the carotid bodies, tiny clusters of cells in the neck near the carotid artery that sense oxygen levels in the blood.
These can be targeted safely with medication, they said.
“Our goal is to target the carotid bodies, and we are importing a new drug that is being repurposed by us to quench carotid body activity and inactivate ‘remotely’ the lateral parafacial region safely, i.e., without needing to use a drug that penetrates the brain.”
This finding could lead to new treatments for high blood pressure, especially for people who also have sleep apnea, as we know carotid bodies are activated in these patients when they stop breathing at night.
Hypertension is commonly referred to as the "silent killer" due to its lack of noticeable symptoms. Unchecked, it progressively damages your arteries and vital organs.
It occurs when the pressure in your blood vessels is consistently higher than normal—usually 140/90 mmHg or more, states the World Health Organization (WHO). The normal and healthy level is estimated to be 120/80 mmHg. Blood pressure increases when the arteries get narrow or stiff, causing the heart to work harder.
At a global level, an estimated 1.28 billion adults aged 30 to 79 years have hypertension, and most of them live in low- and middle-income nations. Alarmingly, 46 percent of them do not even know they have it, and just 1 in 5 keeps it under control, as per WHO statistics.
Also read: Former US Senator Ben Sasse Opens Up About Battle With Terminal Stage 4 Pancreatic Cancer
In the US alone, the Centers for Disease Control and Prevention (CDC) estimates that nearly 47 percent of adults, or roughly 116 million individuals, have hypertension, yet only 24 percent control it well. The economic burden is just as overwhelming, with the US spending $131 billion each year on care related to hypertension.
Exercise, lifestyle changes, and diet are key to preventing hypertension
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