Irregular Sleep, Drinking Caffeine After 3PM Could Raise Your Risk Of Heart Attack And Stroke
I’ve always struggled with inconsistent sleep, staying up late and waking up at different times each day. My love for coffee was also on an all-time high with trying all the season specials. But it is only recently, I learned how this irregular sleep pattern and caffeine could increase my risk of heart attack and stroke. Now, I’m prioritizing a consistent sleep schedule and cutting out caffeine after 3 PM to protect my heart.
A new, shocking study shows that irregular sleep patterns can greatly increase the risk of heart attack and stroke. But that's not all: the timing of your caffeine intake could also play a critical role in your cardiovascular health. If you are struggling with inconsistent sleep patterns and regularly sipping on caffeinated beverages late in the day, you may be unknowingly putting yourself at risk for serious heart-related issues.
For most people, sleep is something of a given and we often only consider ourselves as long as we get our required seven to nine hours. However, according to a recent study conducted by researchers at the Children's Hospital of Eastern Ontario, it may not be that long after all. The study, which included more than 72,000 participants, found that people with irregular sleep patterns—those who fall asleep and wake up at vastly different times each day—face a 26% higher risk of experiencing a heart attack or stroke. This increased risk persisted even for those who managed to get enough sleep. The study followed up participants for eight years to track heart events such as heart attacks, strokes, and heart failure. The conclusions were clear: irregular sleep, even if it's sufficient in duration, is a major cardiovascular risk factor.
The researchers found that those whose sleep patterns were highly irregular had a significantly greater chance of life-threatening heart issues. The more erratic your sleep schedule, the greater the risk, regardless of how many hours you sleep. In fact, people with irregular sleep schedules showed worse cardiovascular health outcomes, including higher rates of high blood pressure, elevated stress hormones, and poor blood sugar and cholesterol management.
Senior scientist Dr. Jean-Philippe Chaput said "sleep regularity may be more relevant than sufficient sleep duration in modulating MACE [major adverse cardiovascular event] risk." In the study, it shows that our bodies are comfortable with consistency, and a varied sleep schedule may interfere with other processes that keep us healthy, especially the heart.
Another daily habit that may be putting your heart at risk is caffeine consumption after 3 PM. According to Dr. Chaput, the experts emphasize the need for a healthy sleep schedule and avoiding caffeine late in the day. Caffeine can stay in your blood for up to eight hours, and its consumption later in the afternoon can disrupt your sleep cycle.
Consistent, good-quality sleep is necessary for maintaining healthy cardiovascular function, and the disruption of this by late-day caffeine intake exacerbates the risks posed by irregular sleep. When you drink coffee, tea, or other caffeinated beverages too late, the stimulant effect on your nervous system makes it harder to fall asleep at a regular time. This can lead to inconsistent sleep patterns, which, as we have seen, can be harmful to heart health.
Dr Chaput insists that humans need to adopt practices that contribute to regularized sleep habits. This can be attained by establishing a proper sleeping and waking schedule, eliminating afternoon intake of stimulants such as caffeine, and making your body clock coincide with the lifestyle one leads.
According to the experts, the disturbance due to irregular sleep patterns impacts more than one physiological process involved in the maintenance of the healthy heart. For example, poor sleep can be associated with increased inflammation of the body, weakened immunity, and altered regulation of blood sugar and cholesterol, all of which contribute to increased blood pressure and weakening endothelial function, both associated with an increased risk for cardiovascular diseases. Sleep also plays a very important role in regulating stress hormones. Poor or disturbed sleep results in increased levels of cortisol, the stress hormone, which increases blood pressure and can have negative impacts on cardiovascular health over time.
Scientists hypothesize that these disturbances trigger a series of negative effects that enhance the risk of developing chronic heart conditions, including hypertension, atherosclerosis, or even heart failure.
In order to protect your heart, experts recommend several proactive measures to improve your sleep patterns and lifestyle. First, maintain a regular sleep schedule whereby you go to bed and wake up at the same time every day, including weekends. Consistency will keep your body's internal clock in check.
Along with regulating your sleep, paying attention to your caffeine habits is just as important. To reduce your risk of heart disease and stroke, experts suggest avoiding caffeine after 3 PM. If you’re sensitive to caffeine, this rule becomes even more critical.
In addition, the introduction of stress-reducing activities like yoga or mindfulness can also be beneficial to lower cortisol levels, and therefore both sleep and heart health can improve. A diet rich in antioxidants, healthy fats, and low on processed sugars also helps maintain cholesterol levels and reduce inflammation.
Apart from the timing of caffeine and your sleep schedule, another very overlooked factor is the quality of your sleep environment. Scientists have long known that the environment in which you sleep has a huge impact on the quality of your rest. Poor quality of sleep, even if your sleep schedule is regular, can cause health risks that are very much the same as those that arise from irregular sleep patterns.
Here’s an additional tip: make sure your bedroom is conducive to restful sleep. This means keeping your room dark, quiet, and cool. A temperature of around 65°F (18°C) is ideal for most people. Consider investing in a comfortable mattress and pillows, and avoid screen time at least 30 minutes before bed to allow your brain to unwind.
Irregular sleep, in association with taking caffeine in late parts of the day, can risk heart attack and stroke, but a simple maintenance of a sleep schedule, the reduction of consumption of afternoon caffeine, and sleep environmental awareness can definitely safeguard one's heart along with total health.
Your sleep is more than just a time for rest; it's a vital component of your long-term health, and maintaining consistency in your sleep habits is one of the best things you can do for your heart.
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Catching a cold during winter is fairly common because viruses spread more easily in packed indoor settings, and cold weather can weaken the immune defence inside the nose, making it harder to fight infections. Having a stuffy nose or a mild cough is one thing, but many people often confuse their illness with a cold when it may actually be flu. Flu symptoms are usually more intense and can include fever, headaches and body aches, along with a dry cough and sore throat. A cold, on the other hand, tends to peak within two to three days, with recovery usually taking about a week.
With a strong flu strain causing disruption across the UK, knowing how to tell the difference between a cold and flu has become especially important. Berkshire NHS, which has around 17,100 followers on TikTok, has outlined three key differences between the two illnesses.
In a caption, the community NHS trust said: “Cold and flu symptoms can look similar, but flu is usually more severe. The flu vaccine helps protect against flu. Visit the NHS website to learn more.”
The video features an NHS staff member pointing out three signs as she walks toward the correct option. The first is that flu comes on suddenly, often within a few hours, while a cold mainly affects the nose and throat. The final sign is that flu can leave you feeling drained and too unwell to go about your normal routine.
Flu often clears up on its own, but it can make some people very unwell. That is why it is important to get vaccinated if you are advised to do so and to follow safe distancing to reduce the spread of infection.
Flu Symptoms 2025
As per NHS, below are the flu symptoms that people need to take care of:
In most cases, a cold can be managed at home without seeing a GP. You should start to feel better within one to two weeks, with symptoms developing over two to three days.
Cold symptoms can last longer in young children. They may become more irritable, struggle with eating and sleeping, breathe through their mouth, and sometimes vomit after coughing. As per NHS, try to get enough rest over the Christmas holidays if possible, drink plenty of fluids, and eat nourishing food to help lower the risk of illness.
Credits: Canva
Mothers who use minoxidil, a widely used hair loss treatment, may increase the risk of infantile hypertrichosis in babies, a condition marked by excessive hair growth across the body, including areas where hair does not usually grow, according to a large international analysis.
Researchers from the Ministry of Health and Family Welfare and the All India Institute of Medical Sciences (AIIMS), New Delhi, reviewed 2,664 worldwide reports of suspected infantile hypertrichosis linked to minoxidil. Of these, 45 cases involved children aged between birth and 23 months.
The analysis showed that 22.2 per cent of these infant cases were associated with maternal exposure to minoxidil. Accidental exposure accounted for 44.4 per cent, while the cause remained unclear in 33.3 per cent of cases. The findings were published in the Archives of Dermatological Research.
Minoxidil is a drug most commonly used to treat pattern hair loss, known as androgenetic alopecia, in both men and women. In higher oral doses, it is also prescribed for severe high blood pressure. The medicine works as a vasodilator, meaning it helps widen blood vessels to improve blood flow.
Infantile hypertrichosis (also called childhood hypertrichosis or werewolf syndrome) is a rare condition marked by excessive hair growth on the face, back, arms, and other areas, appearing from infancy, often with a genetic cause but sometimes triggered by medications (like minoxidil) or underlying conditions, leading to significant cosmetic and psychological distress despite being a generally harmless cosmetic issue
Minoxidil: Eye-Related Side Effects Also Reported
The study also highlighted concerns beyond infant cases. Researchers identified 1,669 global reports of eye-related adverse effects linked to minoxidil use in the general population, including 25 cases reported from India.
Commonly reported eye symptoms included swelling of the eyelids, blurred vision, and central serous chorioretinopathy, a condition in which fluid accumulates beneath the retina and can affect eyesight.
Minoxidil was originally developed to treat high blood pressure. It was later reformulated as a topical treatment for hair loss in both men and women after its hair growth–stimulating side effects were observed. The drug is typically applied directly to the scalp or affected skin areas, the researchers noted.
Despite its proven effectiveness, the researchers raised concerns about the drug’s widespread over-the-counter availability and limited regulatory oversight. These factors, they said, increase the risk of misuse and unintended exposure.
Although minoxidil is generally advised against for use during pregnancy and breastfeeding, the analysis still identified cases of infantile hypertrichosis linked to maternal exposure during these periods.
The researchers noted that minoxidil has also been associated with eye-related side effects in the broader population, prompting renewed questions about its overall safety profile.
“This study aims to examine global reports of infantile hypertrichosis associated with maternal minoxidil exposure and to assess serious and non-serious eye disorder cases reported in India, with the aim of improving awareness about the risks of early-life or accidental exposure,” the authors wrote.
The study was based on data collected up to March 2025 from VigiBase, the World Health Organization’s global database of suspected adverse drug reactions.
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This year had been a year of flu, fiver, bacterial illness and more. One of the over the counter medicine that many people often buy, or is prescribed, especially for bacterial infections is Amoxicillin.
It is a widely prescribed antibiotic that is used to treat bacterial infections in children and adults. It is part of the penicillin class of medications and it inhibits the growth of bacteria and allows the immune system to efficiently eliminate the infection. It is commonly used to treat bacterial infections affecting the respiratory tract, urinary tract, and skin.
However, about 5 to 10 per cent of children prescribed this may develop skin rashes as a common side effect. A rash can develop in two forms: allergic and non-allergic. A rash from the drug Amoxicillin could last up to a week.
A Maculopapular rash is a flat rash that occurs like red patches, raised bumps and spreads over the body.
Hives are itchy, raised red or skin-colored welts that can change shape and location.
Erythema Multiforme are more severe, featuring target-like lesions or bull's-eye shapes with central red spot, pale ring, and red outer ring.
Anaphylactic Reaction is a rare but severe allergic reaction that includes symptoms like difficulty in breathing, swelling of the face, lips, or tongue, hives and rapid drop in blood pressure.
Non-Allergic Amoxicillin Rash are flat, red spots that may be slightly raised, but not harmful. These usually appear o the 5th to 7th day after the start of amoxicillin and can appear on the chest, abdomen, back, face, arms, and legs. It may get worse before it starts to get better.
Warning signs include rashes within two hours of the first amoxicillin dose, difficulty breathing or swallowing, or very itchy hives.
The allergic reaction is caused by one's immune system reacting to that medication as if it were a foreign invader in the body.
More girls than boys develop these rashes, and in children this is even more common. In fact, the rash by amoxicillin was first noted in 1960s, in children who were being treated with ampicillin, recorded the Journal of Pediatrics.
Among treatment, the first step should be to see your physician and immediately stop taking the medication. Drinking water and enough fluids can also help. Your doctor too would prescribe you medications and lotions to soothe your itching.
Hives can also be treated with the over the counter drug Benadryl. However, you must go see your doctor or GP, and not self medicate.
A doctor may treat the rash in various ways, including stopping the medication as the first line of defense. Then the doctor may give oral antihistamines (e.g., cetirizine) for the itch. Some doctors may use topical steroids to help with the itch and redness.
Before visiting your doctor, take photos of your rash, send it to your GP, as if it is contagious. Even after you start the treatment, stay in touch with your healthcare provider for any development.
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