Fasting may reset your body, but can it reset your mind? The new trend of dopamine fasting claims it can. And wait, there's more. This trend also works against dopamine resistance, implying that things that did not make you happier before will now do. You see, dopamine is a part of the brain's reward system and plays an important role in your pleasure reception. While this neurotransmitter is not directly linked to an individual's happiness, it triggers feelings of satisfaction, motivation and pleasure.

However, a person can also reach a stage of dopamine resistance if they continue to indulge in activities that trigger its frequent or constant release. In this case, the individual stops feeling the impact of this neurotransmitter and thus, does feel good or happy.

So does dopamine fasting work?

Dopamine fasting is a practice where individuals limit their exposure to activities or stimuli that typically provide a surge of dopamine. The idea behind dopamine fasting is to reset or recalibrate the brain's reward system. This is usually done by abstaining from gratifying things or experiences like social media, junk food, and even sex. Proponents of dopamine fasting argue that continual overstimulation from digital devices, social media, and easily accessible indulgences has numbed our brain's reward pathways. By regularly denying ourselves these dopamine triggers, the idea claims, we might restore our ability to acquire fulfilment from life's basic pleasures.

How Does Dopamine Imbalance Affect Your Mental Health?

Having low levels of dopamine can make you less motivated and excited about things. In Parkinson's disease, there is not enough dopamine in the areas of the brain important for movement. This leads to problems with muscle stiffness and movements such as walking.

The symptoms of a dopamine imbalance depend on what is causing the problem. They include physical symptoms such as:

• muscle cramps, spasms or stiffness
• digestion problems, such as constipation or reflux
• pneumonia
• trouble sleeping
• moving or speaking more slowly than usual

• feeling tired and unmotivated, or sad and lacking hope
• having low libido (sex drive)
• hallucinations (experiencing something that's not real)

How Can I Adjust My Dopamine Levels?

Adjusting dopamine levels is complicated, as it is involved in many different roles in the brain. Your doctor won't measure your dopamine levels directly, and there is no simple test to measure it. Your symptoms will be the clues that tell your doctor if you have too much or not enough dopamine. They will then prescribe medicines to adjust your dopamine level, based on your symptoms, and make adjustments based on how your body responds and how you feel.

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In India, poor reproductive health awareness remains one of the most overlooked gaps in women’s healthcare. Many women continue to ignore gynecological symptoms, assuming them to be routine, temporary, or too embarrassing to discuss.

Persistent vaginal infections, irregular bleeding, untreated hormonal disorders, chronic pelvic pain, or recurring inflammation are often dismissed until they become severe. In some cases, these untreated or undiagnosed conditions can silently contribute to long-term health risks, including certain cancers.

The Problem With Partial Awareness

Today, many women have heard of conditions like PCOS, endometriosis, or fibroids. But awareness is often incomplete. Women may know the name of a condition, yet not know its warning signs, complications, or when medical attention is necessary.

For example, prolonged hormonal imbalance, obesity, irregular periods, and chronic inflammation may increase the risk of certain gynecological cancers over time. Similarly, lack of awareness about HPV, cervical screening, and vaccination continues to delay prevention and early diagnosis of cervical cancer.

Fertility awareness is another important gap. Many women are not familiar with their menstrual cycle, ovulation pattern, or normal reproductive changes. When women do not know what is normal for their own body, it becomes harder to recognize when something is wrong.

Social media has added another layer to this problem. While it has improved access to health information, it has also created confusion. Quick tips, unverified remedies, and incomplete advice can delay proper diagnosis and treatment.

The Knowledge Gap That Matters

Reproductive literacy is not just about knowing symptoms. It means understanding one’s body, menstrual cycle, sexual health, fertility, contraception, screening options, vaccination, and access to safe healthcare.

Unfortunately, stigma around sexual and reproductive health still prevents many women from seeking timely care. Symptoms such as abnormal discharge, bleeding after intercourse, pelvic pain, or irregular bleeding are often hidden out of fear, shame, or hesitation.

This delay is especially dangerous in cancers such as cervical, uterine, ovarian, and vaginal cancers, where early evaluation can make a major difference.

Actress Lisa Ray was diagnosed with Multiple Myeloma, an incurable but treatable blood cancer, in 2009. She successfully went into remission but experienced a cancer relapse shortly after her wedding in 2012.

During her journey to recovery, she became a prominent advocate for cancer awareness and research. However, it was during this period, at the age of 37, that she also suffered chemo-induced menopause — a topic she brushed aside, not wanting to bring it up out of shame and fear, reflecting the taboo society still associates with the natural end of a woman’s reproductive phase.

In an interaction with HealthandMe, the Oscar-nominated film Water (2005) actress opened up about her experience with chemo-induced menopause.

“I went into chemo-induced menopause at 37. I was given no support. I was completely lost. And even for a subsequent decade after that, I couldn’t find any answers. I didn’t know how to take care of myself. I didn’t know I had options,” she said.

‘I Carried This Burning Secret Inside Me’

The actress shared that she normalized many of her symptoms and avoided speaking openly about menopause despite being candid about cancer.

“I was so vocal about cancer. I’m actually somebody who prefers to be quite truthful about what I’m going through. I don’t really like to hide things. I’m not secretive by nature. And yet, I carried this burning secret inside me for so many years,” she said.

“When I was being lauded as someone who was breaking through the silence of cancer, I was carrying the silent secret inside me. I couldn’t understand why for many years. And I realized today, I was carrying shame.”

She noted that menopause continues to remain a deeply misunderstood and under-discussed subject, despite affecting all women.

‘Menopause Was Like A Black Box’

Lisa said conversations around menopause were absent even within families.

“My mother never talked to me about menopause. Of course, we discussed my period when I got it, but menopause was simply like a black box,” she said.

The actress recalled that discussions around perimenopause and menopause only began when many of her close friends started experiencing symptoms themselves.

Calling the silence around menopause “astonishing” and “extremely unjust,” Lisa said women’s hormonal health continues to be severely underfunded and misunderstood globally.

“Menopause impacts all women. Yet it’s treated like a dark secret,” she told HealthandMe.

Lisa added that once she began researching the issue, she became increasingly frustrated by the lack of awareness and medical attention surrounding menopause and hormonal health.

Menopause Not Getting Enough Attention

The actress said that after moving to Dubai, she began openly discussing menopause on social media, despite initially worrying about public reaction.

“Sometimes in social settings, women would almost shut down or turn away and say, ‘Don’t talk about that.’ But when I put it on social media, maybe it permitted a lot of other women to also find a place to have a conversation or a community,” she said.

To bring about change where women can speak freely about the topic and seek treatment early, Lisa has co-founded NuHer, a science-backed health clinic and platform dedicated to midlife care for women. It is designed to support perimenopause and menopause through personalized medical treatments, clinical psychology, and nutritional guidance.

When asked why she chose to focus on menopause and women’s hormonal health, the Four More Shots Please! actress stated, “Menopause is simply not getting the attention that it needs. Women are struggling to get the care that they need and understand their options.”

Lisa explained that while awareness around cancer has steadily improved in India since her multiple myeloma diagnosis in 2009, menopause remains “the next taboo or frontier.”

According to Lisa, NuHer aims to create a safe, science-backed space where women can access support without judgment or dismissal.

“We need a place where women can be heard, where they’re not dismissed, where they’re not gaslit, where they receive all the right science and the options they can choose for this journey,” she told HealthandMe.

She also criticized the tendency to dismiss menopausal symptoms as a “normal” part of aging without offering support or treatment options.

“Women are not broken. Menopause is not a disease like cancer that has to be cured. But women need support. We don’t need to normalize suffering,” Lisa said.

Menopause Is 'Stepping Into Our Power Age’

Speaking about aging and post-menopause life, Lisa argued that society often dismisses older women despite what she described as a biologically important phase of life.

“We’ve had terrible PR as aging women. We are dismissed and considered irrelevant when actually we’re stepping into our power age if we know how to take care of ourselves,” the acclaimed actress told HealthandMe.

However, the problem arises when menopause is left unaddressed, and the hormonal changes cause long-term health impacts, including bone health, heart disease risk, and possibly dementia.

“The problem is with the drop in hormones. If you don’t have strategies and lifestyle changes to support yourself post-menopause, you become a frail woman. Your bones suffer. You’re more prone to heart disease and possibly even dementia,” she said, urging more women to seek medical help during menopause and not suffer in silence.

GLP-1 agonist drugs like Ozempic, Mounjaro, and Wegovy, may not only help treat obesity and diabetes but also improve survival among breast cancer patients, according to a new study.

The research published in JAMA Network Open suggests that the GLP-1 agonist drugs can lower deaths in breast cancer patients as well as cut down the risk of recurrence of the deadly cancer.

Breast cancer patients who used GLP-1 RA had an overall lower risk of death from any cause over a 10-year follow-up period.

Similarly, breast cancer survivors who used GLP1-RAs for diabetes or obesity had a significantly lower risk of their cancer returning over 10 years following their initial treatment.

"This study suggests that GLP-1 drugs may offer protective benefits, potentially improving survival and recurrence risk in some female patients with breast cancer—whether this is related to weight control, improved cardiovascular health, or other mechanisms remains to be studied," said study senior author Bernard F. Fuemmeler, Chair in Cancer Research at Virginia Commonwealth University’s Massey Comprehensive Cancer Center.

The findings were based on a retrospective cohort study examining the electronic health records of more than 840,000 breast cancer patients who were diagnosed between 2006 and 2023 and also were obese or had type 2 diabetes.

GLP-1 Drugs And Breast Cancer

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Widely hailed as a medical breakthrough, the GLP-1s (glucagon-like peptide-1 receptor agonists) act like the gut hormones that regulate appetite and blood sugar.

It acts specifically on obesity and diabetes — well-established risk factors that significantly elevate the risk of breast cancer progression and recurrence.

GLP-1 medications help lower the risk of breast cancer by promoting weight loss and decreasing circulating tumor activity. It also lowers blood sugar.

Studies have showed that people taking GLP-1s also experience fewer chemo side effects. They were less likely to have anemia, blood clots in veins, low levels of white blood cells called neutrophils, low blood platelet count, sepsis, nausea and vomiting, fatigue, cardiomyopathy, and neuropathy after chemotherapy.

However, the Virginia Commonwealth University study researchers noted that further studies are needed to understand the biological mechanisms, if any, between GLP-1 RAs and breast cancer outcomes.

Global Burden of Breast Cancer

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Breast cancer is the most diagnosed cancer worldwide, accounting for over 2.3 million new cases annually.

According to the WHO's International Agency for Research on Cancer (IARC), it is the leading cause of cancer-related deaths among women, resulting in roughly 670,000 deaths globally each year.

It is also one of the most common cancers among women in the US, and accounts for nearly one-third of all female cancer cases.

The average risk of a woman in the US developing breast cancer sometime in her life is about 13 per cent.

Breast cancer patients who are also obese or have type 2 diabetes experience more aggressive cancer growth and worse outcomes. Prior studies have shown that weight loss treatment and surgery following a breast cancer diagnosis are associated with improved heart health and increased survival.