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Happiness is influenced by a complex interplay of various chemicals in our brain, particularly four key neurotransmitters, D.O.S.E or Dopamine, Oxytocin, Serotonin, and Endorphins. These chemicals, often referred to as "happiness chemicals," are responsible for creating feelings of joy, motivation, connection, and calm.
However, when there's a deficiency in any of these, it can significantly affect our mood, energy, and overall well-being. Let’s dive into what these four neurotransmitters are, how their deficiency impacts us, and how we can boost their levels naturally.
Dopamine is often called the "motivation molecule." It plays a major role in enabling motivation, learning, and the pleasure-reward system in the brain. When we accomplish something — whether it’s finishing a project, completing a workout, or achieving a goal — dopamine gives us that sense of satisfaction and determination to continue.
When dopamine levels are low, it can lead to procrastination, low self-esteem, lack of focus, and general fatigue. A person might feel anxious, hopeless, or experience mood swings because the brain isn’t getting the reward signals it needs.
You can increase dopamine levels by setting and achieving small goals, exercising regularly, eating foods rich in L-Tyrosine (such as almonds, avocados, and eggs), and practicing mindfulness or meditation. Engaging in creative activities like writing or drawing also helps boost dopamine levels.
Oxytocin is often referred to as the "love hormone" or "cuddle hormone" because it plays a major role in social bonding and trust. It’s released when we hug, touch, or engage in other forms of physical affection. Oxytocin fosters feelings of connection and emotional intimacy, making it essential for relationships, family bonding, and even team cooperation.
A lack of oxytocin can lead to feelings of loneliness, stress, anxiety, and difficulties in forming or maintaining relationships. Low oxytocin levels are associated with feelings of isolation and disconnection from others.
You can raise your oxytocin levels through physical touch, socialising, spending quality time with loved ones, and even engaging in activities like massage or listening to soothing music. Acts of kindness, such as helping others or volunteering, also help release oxytocin.
Serotonin is responsible for feelings of well-being and contentment. It helps regulate mood, sleep, digestion, and even social behavior. People who have balanced serotonin levels often feel calm, confident, and emotionally stable. Serotonin is crucial in helping people feel valued and significant among their peers.
Low serotonin levels are linked to depression, low self-esteem, irritability, and mood swings. Individuals may feel overly sensitive to criticism, experience panic attacks, or struggle with social phobias when serotonin is deficient.
You can boost serotonin by getting regular exercise, exposing yourself to sunlight, engaging in cold showers or massages, and practicing mindfulness. Simple activities like walking in nature, meditating, or doing yoga are also effective serotonin enhancers.
Endorphins are the body’s natural painkillers. Released in response to stress, pain, or intense physical activity, they help alleviate discomfort and promote a sense of euphoria. Endorphins are what make you feel good after a workout or a hearty laugh, often referred to as the "runner's high."
Without enough endorphins, people may experience anxiety, depression, chronic pain, and insomnia. A deficiency in endorphins can make daily life feel overwhelming and physically draining.
To boost endorphins, engage in laughter, exercise, and stretching activities. Eating spicy foods or dark chocolate can also stimulate endorphin production. Regular massage therapy and meditation are other ways to naturally elevate endorphin levels.
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A fall at home might look small, but for women older than 65, a broken hip can be a big and serious health problem. In real medical terms, this condition has a 20 to 30 percent chance of being deadly within the first year.
As people get older, their bones get weaker because of osteoporosis, which makes them more likely to break even from small falls. However, the bigger problem starts once the injury happens.
According to World Health organization (WHO), around 60 per cent of people living with osteoarthritis are women, yet awareness remains limited until symptoms begin to interfere with mobility and daily function.
Reports show that 70 per cent of women will get arthritis and osteoporosis. Most of them had no idea it was coming. HealthandMe spoke to experts to understand the reasons behind the trend.
Dr Gurdeep Avinash Ratra, Consultant - Orthopedics and Joint Replacement, Manipal Hospitals, Gurugram said that the development of these disorders is gradual and closely tied to physiological changes.
“After the age of 30, there is a steady decline in muscle mass, accompanied by a more rapid reduction in strength and power. With menopause, the significant fall in estrogen levels removes natural protection for bone density and joint health. Over time, this leads to increased bone fragility, reduced muscular support, and stress on joints, thereby elevating the risk of fractures and chronic joint conditions,” Ratra told HealthandMe.
Health Coach Prashant Desai in a post on social media platform X, noted that after the age of 30:
Experts said a hip fracture needs to be treated right away as a serious medical problem that requires care from many different medical specialists, not just a doctor who focuses on bones.
Dr Rajesh Kumar Verma, Director – Orthopedics & Joint Replacement, Max Super Speciality Hospital, Vaishali explained that limited movement can cause blood clots, chest infections, pressure sores, and loss of muscle quickly. Many patients also face a quick drop in their ability to take care of themselves, which can impact both their body and mind.
Also read: Suffering From Mid-back Pain? Doctors Say It May Be Spinal TB
“Delayed treatment further increases risk. Early surgery and prompt recovery treatment help increase the chances of surviving and recovering better,” Verma told HealthandMe.

What to avoid
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World Health Day serves as a reminder that regular preventive health check-ups stand as mandatory health assessments that all women need to undergo for their long-term health.
Many serious conditions, such as breast cancer, cervical cancer, thyroid disorders, diabetes, and cardiovascular diseases, often remain silent in their early stages, making regular screening the most effective way to detect them early, when treatment is simpler, less invasive, and more successful.
Preventive healthcare enables women to take a proactive role in managing their health rather than responding to illness at an advanced stage. Early detection not only improves clinical outcomes but also effectively decreases treatment difficulties, emotional distress and financial costs while providing superior long-term life quality.
This also helps in identifying risk factors early, allowing timely lifestyle modifications that can prevent disease onset altogether.
Despite this, women often deprioritize their own health due to the multiple roles they juggle, balancing careers, caregiving responsibilities, and family needs. There is also a continued hesitation around discussing reproductive and intimate health concerns, along with a lack of awareness, fear of diagnosis, and social stigma, all of which contribute to delays in seeking timely care.
In many cases, women assume that the absence of symptoms indicates good health, which is a common but risky misconception.
Routine screenings such as Pap smears for cervical health, regular breast examinations, mammography where indicated, thyroid function tests, and basic metabolic screenings like blood sugar and cholesterol levels are critical tools in preventive care.
Periodic health check-ups also provide an opportunity for counselling on nutrition, mental well-being, hormonal health, and lifestyle management, areas that are often overlooked but equally important.
World Health Day serves as a reminder to shift from a reactive to a preventive approach. Prioritizing regular health check-ups, normalizing conversations around women’s health, and encouraging a culture of self-care can significantly improve outcomes. Investing in preventive healthcare is one of the most powerful steps women can take towards leading healthier, longer, and more empowered lives.
Some believe that stress dreams are caused by poor digestion. (Photo credit: iStock)
The root of many health issues stems from the sleep pattern we imbibe in our daily lives. Beyond that, sleep can also act as a mirror to your mental and emotional state. When stress builds up, it rarely switches off at bedtime; instead, it shows up through vivid dreams, frequent night waking, or a sense of anxiety in the early hours of the morning. Dr. Shiva Kumar R, Head and Senior Consultant—Neurology, Manipal Hospital, Sarjapur Road, decoded the link between stress dreams and early morning anxiety.
One of the most common signs is having stress dreams. These dreams are often very strong, repetitive, or emotionally charged, like being chased, not being ready for an exam, or losing control of a situation. Your brain uses them to work through thoughts and feelings that aren't fully formed. When you don't fully deal with your stress, your mind keeps working on it while you sleep.
Waking up at night is another sign you should pay attention to. If you wake up several times without a clear physical reason, it could be because you are more alert. Stress keeps your nervous system in a semi-active state, which makes it harder for your body to get the deep, restorative sleep it needs. Because of this, even small noises can wake you up.
Is there a solution?
Early morning anxiety, where you wake up with a sense of dread or racing thoughts, is also closely tied to stress. Cortisol, the body’s stress hormone, naturally rises in the early morning. However, when you’re overwhelmed, this spike can feel more intense, triggering anxious thoughts before your day even begins.
These patterns are more than just interruptions; they are signs. Your sleep needs attention, balance, and care. Keeping a regular sleep schedule, limiting screen time before bed, using relaxation techniques, or writing down your thoughts can all help lighten your mental load.
If these feelings don't go away, it might be a good idea to look into what is causing them or get help from a professional. The first step toward better mental and emotional health may be to pay attention to what your sleep is trying to tell you.
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