Happiness is influenced by a complex interplay of various chemicals in our brain, particularly four key neurotransmitters, D.O.S.E or Dopamine, Oxytocin, Serotonin, and Endorphins. These chemicals, often referred to as "happiness chemicals," are responsible for creating feelings of joy, motivation, connection, and calm.

However, when there's a deficiency in any of these, it can significantly affect our mood, energy, and overall well-being. Let’s dive into what these four neurotransmitters are, how their deficiency impacts us, and how we can boost their levels naturally.

Dopamine: The Motivation and Reward Chemical

Dopamine is often called the "motivation molecule." It plays a major role in enabling motivation, learning, and the pleasure-reward system in the brain. When we accomplish something — whether it’s finishing a project, completing a workout, or achieving a goal — dopamine gives us that sense of satisfaction and determination to continue.

Deficiency Effects:

When dopamine levels are low, it can lead to procrastination, low self-esteem, lack of focus, and general fatigue. A person might feel anxious, hopeless, or experience mood swings because the brain isn’t getting the reward signals it needs.

Boosting Dopamine:

You can increase dopamine levels by setting and achieving small goals, exercising regularly, eating foods rich in L-Tyrosine (such as almonds, avocados, and eggs), and practicing mindfulness or meditation. Engaging in creative activities like writing or drawing also helps boost dopamine levels.

Oxytocin: The Bonding Chemical

Oxytocin is often referred to as the "love hormone" or "cuddle hormone" because it plays a major role in social bonding and trust. It’s released when we hug, touch, or engage in other forms of physical affection. Oxytocin fosters feelings of connection and emotional intimacy, making it essential for relationships, family bonding, and even team cooperation.

Deficiency Effects:

A lack of oxytocin can lead to feelings of loneliness, stress, anxiety, and difficulties in forming or maintaining relationships. Low oxytocin levels are associated with feelings of isolation and disconnection from others.

Boosting Oxytocin:

You can raise your oxytocin levels through physical touch, socialising, spending quality time with loved ones, and even engaging in activities like massage or listening to soothing music. Acts of kindness, such as helping others or volunteering, also help release oxytocin.

Serotonin: The Mood Stabiliser

Serotonin is responsible for feelings of well-being and contentment. It helps regulate mood, sleep, digestion, and even social behavior. People who have balanced serotonin levels often feel calm, confident, and emotionally stable. Serotonin is crucial in helping people feel valued and significant among their peers.

Deficiency Effects:

Low serotonin levels are linked to depression, low self-esteem, irritability, and mood swings. Individuals may feel overly sensitive to criticism, experience panic attacks, or struggle with social phobias when serotonin is deficient.

Boosting Serotonin:

You can boost serotonin by getting regular exercise, exposing yourself to sunlight, engaging in cold showers or massages, and practicing mindfulness. Simple activities like walking in nature, meditating, or doing yoga are also effective serotonin enhancers.

Endorphins: The Pain Reliever

Endorphins are the body’s natural painkillers. Released in response to stress, pain, or intense physical activity, they help alleviate discomfort and promote a sense of euphoria. Endorphins are what make you feel good after a workout or a hearty laugh, often referred to as the "runner's high."

Deficiency Effects:

Without enough endorphins, people may experience anxiety, depression, chronic pain, and insomnia. A deficiency in endorphins can make daily life feel overwhelming and physically draining.

Boosting Endorphins:

To boost endorphins, engage in laughter, exercise, and stretching activities. Eating spicy foods or dark chocolate can also stimulate endorphin production. Regular massage therapy and meditation are other ways to naturally elevate endorphin levels.

High blood pressure (BP) has become a public health problem that is driving cardiovascular diseases like heart attacks and strokes globally. While medications are important to keep hypertension under control, lifestyle changes and healthy practices are also crucial.

Several global health guidelines recommend regular physical activity, but adhering to exercise programs daily becomes a challenge for many people. But in the overtly busy schedules, sparing 10 minutes for an exercise regimen can be easier than travelling to the gym.

A large randomized clinical trial, published in the Journal of the American College of Cardiology (JACC), has proved that a traditional Chinese mind-body practice — baduanjin — may help lower blood pressure, that too, without any equipment.

Baduanjin is a slow, structured movement, focused on deep breathing and meditation.

Importantly, the clinical trial proved that the ancient Chinese technique could lower BP as effectively as brisk walking.

In people practicing baduanjin, BP reductions were seen after three months and were sustained for one year.

"Given its simplicity, safety, and ease with which one can maintain long-term adherence, baduanjin can be implemented as an effective, accessible, and scalable lifestyle intervention for individuals trying to reduce their blood pressure," said Jing Li, Director, National Center for Cardiovascular Diseases in Beijing, China.

Baduanjin: The 10 Minute Routine

Baduanjin is a standardized eight-movement sequence that integrates aerobic, isometric, flexibility, and mind-body components.

It has been in practice for centuries and commonly performed in community settings across China. The routine typically takes 10–15 minutes and requires no equipment and only minimal initial instruction.

Because it is low- to moderate-intensity, it is considered safe and accessible for many adults.

Also read: Cardiovascular Diseases Lead As India’s Top Killer: US Cardiologist Points Out Risk Factors

The Clinical Trial

A team of Chinese researchers led the first large, multicenter randomized trial to look at the impact of baduanjin on blood pressure.

They followed 216 participants, aged 40 years or older, across seven communities to determine changes in 24-hour systolic BP from baseline to 12 and 52 weeks.

Compared to people indulging in self-directed exercise, practicing baduanjin five days a week reduced

• systolic blood pressure by approximately 3 mg Hg
• systolic blood pressure by 5 mg Hg.

Notably, the benefits were sustained even without ongoing monitoring, a key challenge for many lifestyle interventions that struggle to maintain long-term adherence outside structured programs.

"Baduanjin has been practiced in China for over 800 years, and this study demonstrates how ancient, accessible, low-cost

approaches can be validated through high-quality randomized research," said Harlan M. Krumholz, Editor-in-Chief of JACC and the Harold H. Hines, Jr Professor at the Yale School of Medicine.

"The blood pressure effect size is similar to that seen in landmark drug trials, but achieved without medication, cost, or side effects. This makes it highly scalable for community-based prevention, including in resource-limited settings," they added.

Also read: AHA Cholesterol Guidelines 2026: How Indians Can Improve Heart Health

How To Practice Baduanjin

• Stand upright with your feet shoulder-width apart and keep your movements slow and controlled.
• Coordinate each motion with steady, deep breathing, inhaling and exhaling smoothly as you move.
• Move through the traditional eight postures in sequence, focusing on posture, balance, and relaxation rather than speed or force.
• Practice for about 10 to 15 minutes a day in a quiet space, maintaining calm attention throughout.

Are you a working professional? Have you been diagnosed with endometriosis? Worried about how this condition can impact your career? Well, don’t panic! We give you vital tips to manage the symptoms of endometriosis without compromising your professional aspirations. Dr. Kanika Gera Thakral, Consultant – Obstetrics & Gynaecology, Motherhood Hospitals, Greater Noida, spoke about the effects of endometriosis on working women and what women can do to not let the pain take a toll on their work life.

What is endometriosis?

Endometriosis happens when tissue similar to the lining of the uterus grows outside the uterus. These tissues commonly develop on the ovaries, fallopian tubes, or the pelvic lining. Endometriosis affects many women and can impact their daily lives, including their ability to work comfortably. Many women continue their professional responsibilities despite experiencing severe discomfort, fatigue, and pain.

Raising awareness about the condition and encouraging supportive workplaces can help women manage both their health and career more effectively. Since it is a progressive disorder, timely intervention remains key to managing it. In many cases, women live with symptoms for several years before receiving the correct diagnosis, which can delay treatment and affect their quality of life.

Read more: The Right Approach To Manage Endometriosis

The workplace challenge

Many working women who are diagnosed with endometriosis tend to experience symptoms such as pelvic pain, cramps, fatigue, nausea, and heavy menstrual cycles. These symptoms can make it difficult to maintain productivity at work, especially during flare-ups. Hence, women will be unable to concentrate on work or finish the tasks. Some may miss deadlines and meetings due to the painful symptoms. Women will have to skip going to work when the symptoms are intense and will have to rest at home. So, women living with endometriosis may face interruptions in their career growth and reduced working hours. But don’t worry, it is possible to manage this condition and give your best at work.

1. Long working hours, prolonged sitting, workplace stress, irregular meals, and lack of adequate rest can sometimes worsen symptoms of endometriosis.
2. Apart from physical discomfort, the condition can also affect emotional well-being. Living with chronic pain may lead to stress, anxiety, or frustration, which can indirectly impact workplace confidence and productivity.

Strategies for managing work and endometriosis

It is necessary for women with endometriosis to go for regular check-ups and follow-ups with the doctor. Women can continue to pursue their professional goals by adopting practical strategies to manage the condition. Open communication with employers when it comes to flexible schedules can help overcome stress and anxiety. Women should have access to remote working to avoid unnecessary travel due to pain.

The work-from-home option can be given to the women when needed by them. Planning demanding tasks during times of higher energy and maintaining a balanced daily routine can also improve productivity at work. Women should make sure to keep essential medications, a heating pad, or comfort aids at their desk to be able to relieve sudden discomfort. Likewise, using ergonomic seating or maintaining good posture while working may reduce pelvic and even back discomfort. Women should also connect to support groups that help to provide emotional reassurance and useful coping strategies that include yoga and meditation.

Lifestyle habits also play an important role. Regular physical activity, adequate sleep, stress-management techniques such as yoga or meditation, and following an anti-inflammatory diet rich in fruits, vegetables, whole grains, and healthy fats may help reduce flare-ups.

Read more: Women With Endometriosis Are Earning Less, Reveals Study

Treating endometriosis

Treatment is particularly based on the severity of symptoms. Women will be advised lifestyle modifications such as regular exercise, stress management, and an anti-inflammatory diet. Non-steroidal anti-inflammatory drugs may help reduce discomfort. Hormonal therapies may also be used to control symptoms. Some women will be advised to undergo laparoscopy to remove endometriotic cysts. Minimally invasive surgery can help remove lesions and restore pelvic anatomy, which may also improve fertility in some cases. In advanced cases, surgery can be recommended to women.

With timely care and supportive workplaces, women can pursue their ambitions without letting endometriosis interfere with their careers.

Four years after suffering from a rare neurological condition known as Stiff-Person Syndrome, Céline Dion, known for power ballads like My Heart Will Go On and Because You Loved Me, has announced her return to the stage.

The incurable condition had affected her singing voice and even her ability to walk.

In a message on her Instagram page, the singer announced plans to play a 10-night residency at the 40,000-capacity Paris La Défense Arena in September and October.

Calling her comeback "the best gift of my life", 58-year-old Dion said: "I'm doing great, managing my health, feeling good. I'm singing again, even doing a little bit of dancing.

"I'm so ready to do this. I'm feeling good, I'm strong, I'm feeling excited, obviously, [and] of course, a little nervous," she said, while thanking her fans for the “prayers and support, kindness and love”.

What Is Stiff Person Syndrome

Stiff-Person Syndrome is a neurological disease caused by the signals from the nerves to the muscles not working properly. It affects an estimated 8,000 people worldwide.

It is also an autoimmune is a neurological disease caused by the signals from the nerves to the muscles not working properly. It affects an estimated 8,000 people worldwide.

It is also an autoimmune condition, that is linked to diseases such as type 1 diabetes, thyroiditis, vitiligo, and pernicious anemia.

For some, it can be debilitating. SPS is progressive, meaning it gets worse over time. There is no known cure.

Common symptoms may include:

• Stiff muscles in the torso, arms, and legs
• Greater sensitivity to noise, touch, and emotional distress, which can set off muscle spasms

The condition is also more common among women than men, and affects people between the ages of 20 and 60.

While there is no known cure for SPS, current treatments such as intravenous immunoglobulin (IVIg) can help manage the symptoms.

Stiff-Person Syndrome: Celine Dion’s Diagnosis

Dion announced her diagnosed with Stiff Person Syndrome (SPS) in December 2022 in an emotional Instagram video. The condition had affected "every aspect of my daily life", she told her fans.

The best-selling artists of all time began noticing her symptoms, such as feeling "a little spasm" while performing on stage. She found her “voice was struggling", BBC reported.

Even though she experimented with her singing to ease the stress on her vocal cords, her condition worsened. She also began facing difficulties while walking.

"It's like somebody is strangling you. It's like somebody is pushing your larynx [or] pharynx," she told NBC News.

Determined to get back on her feet and sing, worked "all my body and soul, from head to toe, with a medical team", French Vogue magazine reported.

"Five days a week, I undergo athletic, physical, and vocal therapy. I work on my toes, my knees, my calves, my fingers, my singing, my voice."

The intense workouts enabled her to make a comeback at the 2024 Paris Olympics, singing Edith Piaf's classic Hymne à l'Amour from the Eiffel Tower.