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Happiness is influenced by a complex interplay of various chemicals in our brain, particularly four key neurotransmitters, D.O.S.E or Dopamine, Oxytocin, Serotonin, and Endorphins. These chemicals, often referred to as "happiness chemicals," are responsible for creating feelings of joy, motivation, connection, and calm.
However, when there's a deficiency in any of these, it can significantly affect our mood, energy, and overall well-being. Let’s dive into what these four neurotransmitters are, how their deficiency impacts us, and how we can boost their levels naturally.
Dopamine is often called the "motivation molecule." It plays a major role in enabling motivation, learning, and the pleasure-reward system in the brain. When we accomplish something — whether it’s finishing a project, completing a workout, or achieving a goal — dopamine gives us that sense of satisfaction and determination to continue.
When dopamine levels are low, it can lead to procrastination, low self-esteem, lack of focus, and general fatigue. A person might feel anxious, hopeless, or experience mood swings because the brain isn’t getting the reward signals it needs.
You can increase dopamine levels by setting and achieving small goals, exercising regularly, eating foods rich in L-Tyrosine (such as almonds, avocados, and eggs), and practicing mindfulness or meditation. Engaging in creative activities like writing or drawing also helps boost dopamine levels.
Oxytocin is often referred to as the "love hormone" or "cuddle hormone" because it plays a major role in social bonding and trust. It’s released when we hug, touch, or engage in other forms of physical affection. Oxytocin fosters feelings of connection and emotional intimacy, making it essential for relationships, family bonding, and even team cooperation.
A lack of oxytocin can lead to feelings of loneliness, stress, anxiety, and difficulties in forming or maintaining relationships. Low oxytocin levels are associated with feelings of isolation and disconnection from others.
You can raise your oxytocin levels through physical touch, socialising, spending quality time with loved ones, and even engaging in activities like massage or listening to soothing music. Acts of kindness, such as helping others or volunteering, also help release oxytocin.
Serotonin is responsible for feelings of well-being and contentment. It helps regulate mood, sleep, digestion, and even social behavior. People who have balanced serotonin levels often feel calm, confident, and emotionally stable. Serotonin is crucial in helping people feel valued and significant among their peers.
Low serotonin levels are linked to depression, low self-esteem, irritability, and mood swings. Individuals may feel overly sensitive to criticism, experience panic attacks, or struggle with social phobias when serotonin is deficient.
You can boost serotonin by getting regular exercise, exposing yourself to sunlight, engaging in cold showers or massages, and practicing mindfulness. Simple activities like walking in nature, meditating, or doing yoga are also effective serotonin enhancers.
Endorphins are the body’s natural painkillers. Released in response to stress, pain, or intense physical activity, they help alleviate discomfort and promote a sense of euphoria. Endorphins are what make you feel good after a workout or a hearty laugh, often referred to as the "runner's high."
Without enough endorphins, people may experience anxiety, depression, chronic pain, and insomnia. A deficiency in endorphins can make daily life feel overwhelming and physically draining.
To boost endorphins, engage in laughter, exercise, and stretching activities. Eating spicy foods or dark chocolate can also stimulate endorphin production. Regular massage therapy and meditation are other ways to naturally elevate endorphin levels.
Credits: Canva
America is aiming to align with global trends in sun protection. On December 11, the Food and Drug Administration proposed allowing the use of bemotrizinol in sunscreens — an ingredient that has been widely used in other countries for years.
Bemotrizinol provides stable, long-lasting defence against both types of UV rays that can harm the skin. According to the FDA announcement, it is gentle enough to be safe for young children and could be on shelves in time for next summer.
"The agency has historically moved too slowly in this area, leaving Americans with fewer options than consumers abroad. We’re continuing to modernize the regulation of sunscreen and other over-the-counter drug products,” FDA Commissioner Marty Makary said in a press statement. “Americans deserve timely access to the best safe, effective, and consumer-friendly over-the-counter products available.”
Bemotrizinol, also called BEMT, is a chemical that absorbs both UVB and UVA rays. If those terms sound familiar, it’s likely because you’ve seen them on nearly every sunscreen bottle. The sun emits ultraviolet (UV) radiation, which is exactly what sunscreen is designed to block.
UVB and UVA describe different kinds of rays, according to the University of Texas MD Anderson Cancer Center. For our skin, the difference isn’t huge. UVA causes tanning and burns faster than UVB, while UVB can be partially blocked by barriers like windows or clouds.
About 95% of UV reaching the ground is UVA, with UVB making up the remaining 5%, according to the Anderson Cancer Center. Sunscreens work in two ways: creating a physical barrier with minerals or using chemicals that absorb rays before they reach the skin. BEMT falls into the latter category.
BEMT ticks many boxes for an effective sunscreen ingredient. It is broad-spectrum, shielding against both UVA and UVB, and achieves higher SPF protection in smaller amounts than some other popular chemicals, according to Certified Laboratories and the FDA via USA Today. It is also photostable, meaning it breaks down more slowly when exposed to sunlight, and being oil-soluble makes it easy to mix into creams.
The ingredient is minimally absorbed into the body through the skin and rarely causes irritation, which is why the FDA considers it safe for children as young as six months old.
Following the proposal, the FDA has opened a 45-day public comment period. Once the agency reviews feedback and confirms safety, it will issue a final order to allow the ingredient. Over-the-counter approvals are generally faster than the one-to-two years typical for prescription drugs. The FDA told Today that BEMT sunscreens could be available by summer or fall of 2026.
Recent holdups at the U.S. Food and Drug Administration in clearing new sunscreen ingredients have largely stemmed from long-standing regulatory slowdowns, which left American shoppers with fewer choices than those offered in many other countries.
The agency’s plan to permit the use of bemotrizinol, a filter already common abroad, marks a step toward updating its approach to sunscreen oversight and giving people access to more advanced formulas. Updates from the agency note that bemotrizinol delivers steady, broad-spectrum defense against UVA and UVB rays and is mild enough for children, bringing U.S. standards closer to what is widely available worldwide.
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As a strong wave of “superflu” and other seasonal infections moves through the country, large numbers of people have fallen ill this winter. The rise has been serious enough for some NHS officials to advise anyone with symptoms to wear a mask. Newly released data shows how quickly the situation has worsened, with flu admissions jumping by 55 percent in a single week.
This sharp climb has pushed the NHS into what leaders describe as a “worst case scenario” for December. As per The Independent, over the past week, hospitals saw an average of 2,660 daily admissions for flu, the highest figure ever recorded at this point in the year. With so many people under the weather, many are trying to work out which pain reliever offers better comfort. An expert previously spoke to the Mirror on this exact point.
Figures released today highlight the severity of the situation, with flu hospitalisations having surged by more than half (55%) in just one week. This massive increase has officially plunged the NHS into a "worst case scenario" situation for the month of December. Last week, an average of 2,660 patients per day were admitted to hospital beds with flu, marking the highest number ever recorded for this time of year.
With so many people falling poorly, it can be helpful to know which medicine is best to take. Thankfully an expert previously spoke to the Mirror about ibuprofen and paracetamol. Abbas Kanani, the superintendent pharmacist at Chemist Click, said: "Paracetamol is probably more effective at bringing down temperature, so it's almost like a double-whammy, you get rid of your headache and bring your temperature down. "But if you feel that you have more body aches, that's your main symptom, then ibuprofen is probably slightly better as it's an anti-inflammatory."
However, he cautioned users to be mindful of potential allergies to ibuprofen, which belongs to a specific class of drugs.
He also revealed that many people are unaware that they can actually take both medicines together when feeling particularly unwell. "If you feel that one isn't enough you can take ibuprofen as well as paracetamol, you can take them together. A lot of people don't know that it's not one or the other, you can put them together as they work in different ways."
While these two medications can alleviate aches, pains and fevers, as well as mild cold and flu symptoms, Abbas notes that they won't be particularly effective for those struggling with coughs and nasal congestion.
To address these specific symptoms, you'd need to utilise cold and flu products instead.
Many people assume one medicine works better for all flu complaints, but the expert’s guidance shows that the right choice depends on what you’re feeling. Fever and headache respond more readily to paracetamol, while body aches and inflammation may ease faster with ibuprofen. For coughs or blocked sinuses, cold-and-flu formulas are needed because standard pain relievers do not target those issues.
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Public forums often turn into places where people share worries they hesitate to bring up with a doctor. Reddit, especially, saw a surge of unusual yet genuinely important questions about sexually transmitted infections this year in 2025. A large number of these posts came from young adults who felt unsure about new symptoms, confused about how infections spread or overwhelmed by the flood of sexual-health content circulating online.
The ten questions below may seem odd at first glance, but each one raises a medically sensible point. Together, they show how gaps in sexual-health awareness still shape the way people talk about intimacy and illness on the internet.
STI refers to a Sexually Transmitted Infection. It is an infection passed through sexual activity such as oral, vaginal or anal contact, and in some cases through non-sexual routes such as blood exposure or mother-to-child transmission.
These infections can be caused by bacteria, viruses or parasites. Some lead to clear symptoms while others remain silent, but untreated cases can result in serious health problems. When an STI begins to cause notable medical issues, it is often described as a Sexually Transmitted Disease (STD).
One user who had only engaged in oral and anal sex with another virgin noticed marks on their legs and wondered if infections could be “passed down by parents.” The spots disappeared on their own, likely due to shaving irritation, yet the question reveals a common misconception. STIs cannot be inherited genetically. They require actual transmission through sexual contact, blood or childbirth.
This question came from someone who had watched too many alarming clips about PrEP and safe sex on social media. They became so uneasy that they avoided going on dates until they understood the risks. Some infections can spread through oral sex and deep kissing, though the degree of risk varies. Their fear felt intense, but the doubt itself was completely reasonable.
A user in a regional subreddit asked whether STIs even “exist here” because no one talked about them openly. The framing sounded odd, but it reflected the silence that still surrounds sexual health in many places. STIs appear everywhere, though in some communities the subject is rarely discussed.
One of the year’s most unusual but earnest threads came from someone trying to understand whether anonymous sexual setups increase risk. They asked about skin-to-skin contact, bodily fluids and the impact of poor visibility. Though the question seemed strange, experts often point out that uncertainty about partners and surroundings can raise the chance of exposure.
Another thread took a more confrontational tone, suggesting that anyone who uses a glory hole “either already has an STD or doesn’t care.” Replies pushed back, saying that anonymity has many motives and that what truly matters is the use of protection and clarity about risk, not assumptions about a person’s character.
This question was framed like a moral dilemma, but the situation involved real medical timing. A woman had contracted an STI from a partner who had tested too early for the infection to show up on his results. One commenter suggested that the timing hinted at sexual activity very close to the start of their relationship. The discussion blended relationship boundaries with the science of incubation periods.
A worried user described swollen tonsils, tiredness, muscle twitching, stomach cramps, cracking joints, night sweats and more. None of this lined up with any single STI, yet their panic was sincere. The thread showed how anxiety can turn normal bodily sensations into something that feels catastrophic.
A person who had their first sexual experience by giving oral sex to an AFAB partner developed painful cracks on their genitals a few days later, even though there was no genital contact. They feared they had caught an infection. While genital cracks from oral contact alone are unlikely, some infections can move through oral-genital routes. Their confusion made sense even if the symptoms did not match the exposure.
Several users described bumps, redness and irritation, convinced they must have an STI. Many replies explained that chafing, sweat, allergic reactions or grooming habits can look similar to infection symptoms.
Some posters were puzzled when new bodily changes appeared long after a sexual encounter. They mentioned stomach issues, headaches or tiredness. While certain infections do have incubation windows, many unrelated issues can appear around the same time, which can lead people to make the wrong connection.
These questions may sound strange, but nearly all came from people trying to understand their bodies and risks. They also show how much sexual-health education remains incomplete. Proper testing, routine medical visits and clear conversations with professionals are still far more dependable than guessing through anonymous internet threads.
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