Happiness is influenced by a complex interplay of various chemicals in our brain, particularly four key neurotransmitters, D.O.S.E or Dopamine, Oxytocin, Serotonin, and Endorphins. These chemicals, often referred to as "happiness chemicals," are responsible for creating feelings of joy, motivation, connection, and calm.

However, when there's a deficiency in any of these, it can significantly affect our mood, energy, and overall well-being. Let’s dive into what these four neurotransmitters are, how their deficiency impacts us, and how we can boost their levels naturally.

Dopamine: The Motivation and Reward Chemical

Dopamine is often called the "motivation molecule." It plays a major role in enabling motivation, learning, and the pleasure-reward system in the brain. When we accomplish something — whether it’s finishing a project, completing a workout, or achieving a goal — dopamine gives us that sense of satisfaction and determination to continue.

Deficiency Effects:

When dopamine levels are low, it can lead to procrastination, low self-esteem, lack of focus, and general fatigue. A person might feel anxious, hopeless, or experience mood swings because the brain isn’t getting the reward signals it needs.

Boosting Dopamine:

You can increase dopamine levels by setting and achieving small goals, exercising regularly, eating foods rich in L-Tyrosine (such as almonds, avocados, and eggs), and practicing mindfulness or meditation. Engaging in creative activities like writing or drawing also helps boost dopamine levels.

Oxytocin: The Bonding Chemical

Oxytocin is often referred to as the "love hormone" or "cuddle hormone" because it plays a major role in social bonding and trust. It’s released when we hug, touch, or engage in other forms of physical affection. Oxytocin fosters feelings of connection and emotional intimacy, making it essential for relationships, family bonding, and even team cooperation.

Deficiency Effects:

A lack of oxytocin can lead to feelings of loneliness, stress, anxiety, and difficulties in forming or maintaining relationships. Low oxytocin levels are associated with feelings of isolation and disconnection from others.

Boosting Oxytocin:

You can raise your oxytocin levels through physical touch, socialising, spending quality time with loved ones, and even engaging in activities like massage or listening to soothing music. Acts of kindness, such as helping others or volunteering, also help release oxytocin.

Serotonin: The Mood Stabiliser

Serotonin is responsible for feelings of well-being and contentment. It helps regulate mood, sleep, digestion, and even social behavior. People who have balanced serotonin levels often feel calm, confident, and emotionally stable. Serotonin is crucial in helping people feel valued and significant among their peers.

Deficiency Effects:

Low serotonin levels are linked to depression, low self-esteem, irritability, and mood swings. Individuals may feel overly sensitive to criticism, experience panic attacks, or struggle with social phobias when serotonin is deficient.

Boosting Serotonin:

You can boost serotonin by getting regular exercise, exposing yourself to sunlight, engaging in cold showers or massages, and practicing mindfulness. Simple activities like walking in nature, meditating, or doing yoga are also effective serotonin enhancers.

Endorphins: The Pain Reliever

Endorphins are the body’s natural painkillers. Released in response to stress, pain, or intense physical activity, they help alleviate discomfort and promote a sense of euphoria. Endorphins are what make you feel good after a workout or a hearty laugh, often referred to as the "runner's high."

Deficiency Effects:

Without enough endorphins, people may experience anxiety, depression, chronic pain, and insomnia. A deficiency in endorphins can make daily life feel overwhelming and physically draining.

Boosting Endorphins:

To boost endorphins, engage in laughter, exercise, and stretching activities. Eating spicy foods or dark chocolate can also stimulate endorphin production. Regular massage therapy and meditation are other ways to naturally elevate endorphin levels.

Multiple Sclerosis is a chronic and progressive neurological condition affecting an estimated 1.5–2 lakh people in India, and remains one of the country's most overlooked invisible disabilities.

Many of its symptoms, including fatigue, cognitive impairment, chronic pain, visual disturbances, and bladder dysfunction, are often not outwardly visible, contributing to delayed diagnosis, barriers to disability recognition, insurance challenges, and difficulties in accessing long-term care and support.

Declaration at National Policy Dialogue

In a significant step towards strengthening disability-inclusive healthcare and social protection in India, policymakers, neurologists, disability rights advocates, insurance stakeholders, and persons living with Multiple Sclerosis (MS) today endorsed a landmark 10-point Declaration on Invisible Disabilities and Gender at the National Policy Dialogue organized on the occasion of World Multiple Sclerosis Day 2026.

The National Policy Dialogue was held under the theme, "Shaping Policy. Advancing Access. Improving Lives."

"India has made significant progress in recognizing the rights of persons with disabilities, and conversations such as these are essential to ensuring that our laws, policies, and institutions continue to evolve in ways that better reflect the lived experiences of people affected by conditions such as MS," said Menaka Guruswamy, Member of Parliament, Rajya Sabha.

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Barriers to Care and Support

Experts from the Multiple Sclerosis Society of India (MSSI) stated that for people living with Multiple Sclerosis, the challenges often extend far beyond the disease itself.

Delayed access to insurance, high out-of-pocket costs, limited awareness of available entitlements, and the absence of comprehensive patient data continue to create barriers to timely care.

Thus, they expect the Declaration to catalyze stronger insurance inclusion, better access to support systems, and a more robust national understanding of the true burden of MS in India.

The 10-Point Declaration

The Declaration on Invisible Disabilities and Gender outlines a roadmap to strengthen implementation of the Rights of Persons with Disabilities (RPwD) Act, 2016, and improve the inclusion of invisible neurological conditions within India's healthcare, disability, and welfare systems.

Key recommendations include:

• Recognition guidelines for invisible and episodic disabilities under the RPwD Act.
• Flexible disability certification for people with fluctuating conditions.
• Inclusion of MS and other chronic neurological conditions within National Health Mission care pathways.
• Expansion of the Indian MS Registry Network (IMSRN) into a broader national invisible disability registry.
• Affordable access to disease-modifying therapies and long-term neurological care.
• Expanded tele-neurology services across India.
• Gender-sensitive diagnosis and treatment pathways.
• Stronger digital monitoring of disability rights implementation.
• Inclusive workplace policies for invisible disabilities.
• A National Mission on Invisible Disabilities.

Call for Stronger Policy and Healthcare Support

The declaration reflects a growing consensus among stakeholders that India's healthcare and social protection systems must evolve to better address invisible conditions that significantly affect an individual's functional ability, quality of life, and socioeconomic participation.

"Multiple Sclerosis is a complex, unpredictable, and lifelong neurological condition that requires early diagnosis, timely intervention, and sustained access to advanced therapies. While often simplified for patient understanding, the clinical reality is far more challenging and demands a nuanced approach to treatment and long-term care," said Dr. R.K. Dhamija, Distinguished Neurologist, Director, IHBAS, and Chair, National Task Force, NITI Aayog Brain Health Initiative.

"Investing in neurological care is not merely a healthcare expenditure; it is an economic imperative that helps prevent irreversible disability, reduces long-term care costs, and enables people to remain active and productive," Dr. Dhamija added.

For many people, tobacco does not begin as an addiction; it starts as a habit woven into ordinary moments of daily life. A cigarette shared with friends, a smoke break during a stressful day, or chewing tobacco after meals can soon become a routine that feels difficult to avoid.

While these habits may seem harmless in the beginning, tobacco slowly affects nearly every organ in the body, often giving subtle warning signs long before a serious disease is diagnosed.

When The Body Starts Giving Signals

These effects rarely manifest suddenly and usually come after years of prolonged use. It is this slow progress that leads most tobacco users to believe that "I am fine." But there are unmistakable signs of some diseases brought about by the use of tobacco that ought not to be dismissed:

• The Persistent Cough: A cough that has lasted for more than two to three weeks, becomes progressively worse each day, and is associated with a wheeze.

• Unexplained Fatigue: A person feeling breathless or unnaturally tired after having climbed a couple of stairs or walking a short distance can easily attribute this to general fatigue.

• Weight Fluctuations: The unexplained drop in weight can also be caused by some diseases that tobacco is likely to inflict upon the body.

Changes Inside the Mouth

Oral cancer caused by tobacco often appears initially in the form of persistent mouth ulcers, white or red patches inside the mouth, and jaw stiffness. These painful and irritating conditions can be so subtle that a person is not concerned by them.

Persistent changes like the change in your voice pitch or constant throat irritation are not to be taken lightly, either; they could be signs of deeper problems arising. Seeking medical help when it is still in the superficial stages will not only decrease your chances of being treated with aggressive measures but may actually result in an easier way to fight the condition.

Beyond Lungs: Other Effects of the Illness

Tobacco affects much more than just the lungs, and many symptoms associated with chronic conditions often go unnoticed.

• Cardiovascular Strain: Dizziness and chest heaviness are indications of heart problems caused by the presence of toxins in the body.

• Physical Discomfort: Headaches or leg edema may sometimes be seen as manifestations of blood vessel disorders.

The Untapped Power of Prevention

The most important remedy at our disposal is not a complicated surgery but an accurate identification of such conditions at their superficial stage, allowing for minimal and non-invasive treatments.

The human body is an incredibly powerful machine at healing, and the instant the consumption of tobacco ceases, a chain of events kicks off that increases circulation and improves lung function.

If you ever find yourself dealing with a persistent cough, mouth ulcer, or undue fatigue, it is advisable to visit a specialist at the earliest to prevent future complications.

(By Dr Yash Mathur, Senior Head, Neck, Oral, and Robotic Onco-Surgeon at HCG Cancer Hospital, Borivali, Mumbai)

A growing body of global research is beginning to point in one direction: our eyes are under strain like never before. As per the report published on PubMed, myopia is projected to rise significantly worldwide, increasing from about 27% of the global population in 2010 to nearly 52% by 2050, highlighting its emergence as a major public health concern.

Although genetics has long contributed, there appears to be a significant environmental factor associated with how fast this shift has occurred.

Screens have become an integrated part of everyday lives, from the time of waking up to work on digital screens or scroll through phones late into the night. Digital devices are no longer optional but a constant priority.

Work, education, and entertainment are all now done on screens with little or no interruption. The growing generation of gadgets has its own advantages, but its impact has significantly contributed to the alarming rise in cases of myopia.

The Science Behind the Surge: Why Our Eyes Are Struggling

There are three major significant ways prolonged screen time could affect vision:

• Near Vision strain - Prolonged near-vision focus places a constant strain on the eye muscles, causing them to remain contracted. This will eventually lead to elongation of the eyeball and myopia.

• Reduced Blinking due to dry eyes - Screen use decreases the rate of blinking, which causes the eyes to dry out, leading to irritation and instability.

• Lack of Sunlight - Less time outdoors reduces the opportunity to receive sunlight. Sunlight exposure is especially important in children for proper vision development.

From Temporary Strain to Long-Term Damage

Mild discomfort, such as dryness, headaches, and blurred vision, can lead to more chronic issues. Digital eye strain is common among adults and children alike. However, the long-term outcome is the main concern.

Progressive myopia increases the chances of developing serious eye diseases like glaucoma, retinal detachment, and macular degeneration, and having to wear stronger prescription glasses. These aren't just short-term inconveniences; they can create lifelong risks that severely affect the quality of life.

The Post-Pandemic Effect: A Generation at Risk

The days when children spent their time flying kites, playing marbles, feeling the wind on their faces, and returning home with dust-covered hands have gradually faded into memory. The COVID-19 pandemic accelerated an already existing trend.

The screen time increased as many schools transitioned to online education and remote workers increased due to the pandemic. Above all, children experienced a sudden reduction in outdoor activity with increased exposure to digital devices.

The phase indicated a noticeable drop in the vision of the people. This period has often been referred to as a phase of “quarantine myopia,” where many young individuals reported a noticeable decline in vision.

As individuals return to normalcy, the habits that were established are continuing, and concern is being raised about a generation having poorer visual health.

Prevention Over Cure: Rethinking Visual Hygiene

Consistent habits are needed to address this issue:

• 20-20-20 rule: After every 20 minutes of looking at a digital device with stress, try to look at something far away (at least 20 feet away) for approximately 20 seconds to relax your eye muscles and reduce the stress placed on your eyes.

• Limit recreational screen time: Reducing the amount of time spent using screens will help reduce the likelihood of developing eye strain and progression of myopia, especially in children.

• Proper viewing distance and posture: Keeping screens at approximately one arm's length will help to minimise the amount of stress placed on your eyes and body.

• Encourage Outdoor Activity: Children between the ages of 6 and 16 years should be encouraged to engage in outdoor activities more frequently and not replace books with tablets or iPads.

• Mandatory Vision Screening: Vision screening and eye check-ups prior to school admissions should be made mandatory by the government, as early detection of myopia can help prevent further complications.

A Call for Collective Responsibility

The increase in use of screens is not an isolated event; it is part of the larger trend affecting how we live and work. To address this issue, we need to develop awareness among individuals, families, schools, and workplaces about proper screen use. A balanced daily routine, guided by parents, plays a crucial role in maintaining healthy vision in children.

Collective responsibility among teachers, parents, and government authorities is essential to prevent visual complications, as children represent our future generations. Greater public awareness around digital eye strain and eye health is also necessary, as it often serves as a precursor to multiple health complications.

Eye health must be seen as an essential part of overall well-being. The current trend may still be a developing issue, but it requires urgent attention. Acting early, with informed choices and preventive care, can ensure that technological progress does not come at the cost of long-term vision health.