Happiness is influenced by a complex interplay of various chemicals in our brain, particularly four key neurotransmitters, D.O.S.E or Dopamine, Oxytocin, Serotonin, and Endorphins. These chemicals, often referred to as "happiness chemicals," are responsible for creating feelings of joy, motivation, connection, and calm.

However, when there's a deficiency in any of these, it can significantly affect our mood, energy, and overall well-being. Let’s dive into what these four neurotransmitters are, how their deficiency impacts us, and how we can boost their levels naturally.

Dopamine: The Motivation and Reward Chemical

Dopamine is often called the "motivation molecule." It plays a major role in enabling motivation, learning, and the pleasure-reward system in the brain. When we accomplish something — whether it’s finishing a project, completing a workout, or achieving a goal — dopamine gives us that sense of satisfaction and determination to continue.

Deficiency Effects:

When dopamine levels are low, it can lead to procrastination, low self-esteem, lack of focus, and general fatigue. A person might feel anxious, hopeless, or experience mood swings because the brain isn’t getting the reward signals it needs.

Boosting Dopamine:

You can increase dopamine levels by setting and achieving small goals, exercising regularly, eating foods rich in L-Tyrosine (such as almonds, avocados, and eggs), and practicing mindfulness or meditation. Engaging in creative activities like writing or drawing also helps boost dopamine levels.

Oxytocin: The Bonding Chemical

Oxytocin is often referred to as the "love hormone" or "cuddle hormone" because it plays a major role in social bonding and trust. It’s released when we hug, touch, or engage in other forms of physical affection. Oxytocin fosters feelings of connection and emotional intimacy, making it essential for relationships, family bonding, and even team cooperation.

Deficiency Effects:

A lack of oxytocin can lead to feelings of loneliness, stress, anxiety, and difficulties in forming or maintaining relationships. Low oxytocin levels are associated with feelings of isolation and disconnection from others.

Boosting Oxytocin:

You can raise your oxytocin levels through physical touch, socialising, spending quality time with loved ones, and even engaging in activities like massage or listening to soothing music. Acts of kindness, such as helping others or volunteering, also help release oxytocin.

Serotonin: The Mood Stabiliser

Serotonin is responsible for feelings of well-being and contentment. It helps regulate mood, sleep, digestion, and even social behavior. People who have balanced serotonin levels often feel calm, confident, and emotionally stable. Serotonin is crucial in helping people feel valued and significant among their peers.

Deficiency Effects:

Low serotonin levels are linked to depression, low self-esteem, irritability, and mood swings. Individuals may feel overly sensitive to criticism, experience panic attacks, or struggle with social phobias when serotonin is deficient.

Boosting Serotonin:

You can boost serotonin by getting regular exercise, exposing yourself to sunlight, engaging in cold showers or massages, and practicing mindfulness. Simple activities like walking in nature, meditating, or doing yoga are also effective serotonin enhancers.

Endorphins: The Pain Reliever

Endorphins are the body’s natural painkillers. Released in response to stress, pain, or intense physical activity, they help alleviate discomfort and promote a sense of euphoria. Endorphins are what make you feel good after a workout or a hearty laugh, often referred to as the "runner's high."

Deficiency Effects:

Without enough endorphins, people may experience anxiety, depression, chronic pain, and insomnia. A deficiency in endorphins can make daily life feel overwhelming and physically draining.

Boosting Endorphins:

To boost endorphins, engage in laughter, exercise, and stretching activities. Eating spicy foods or dark chocolate can also stimulate endorphin production. Regular massage therapy and meditation are other ways to naturally elevate endorphin levels.

Glomerular Diseases affect the glomeruli, which are very small filtering units in the human kidney, and when they get damaged due to disorders, the filters leak blood and vital proteins into the urine and fail to remove waste efficiently. Eventually, these problems can lead to chronic kidney disease or kidney failure. As per its treatment, medications are used to slow kidney damage, manage blood pressure, and reduce protein leakage.

Notably, a new study has revealed hope in this condition by finding that a well-known drug can be very effective in slowing damage if the patient has Glomerular Diseases, and that common drug is Finerenone, which is often prescribed for heart and kidney diseases associated with type 2 diabetes.

The trial was participated in by 903 participants with glomerular diseases. The drug finerenone was given to them. The results show that compared with placebo, it slowed kidney damage, reduced albuminuria, and lowered the risk of kidney failure or sustained loss of kidney function.

Thus, the study clearly indicates that the drug called finerenone may play an important role in protecting kidney function in patients with glomerular diseases.

The research was conducted through subgroup analysis of a phase 3, randomized, double-blind, placebo-controlled trial conducted across 24 countries and regions, focusing on participants with an investigator-reported glomerular disease.

The study was conducted on a large scale, having conducted the research for months in 24 countries and regions. The trial also took care of other important details and implemented all required paperwork, thus securing approvals by regulatory authorities along with ethics committees in every center. Other than that, the participants were required to submit written informed consent. Moreover, an independent data monitoring committee performed safety monitoring throughout the tests.

How To Keep Kidneys Healthy?

Dietary habits can contribute to kidney strain, particularly when busy schedules encourage reliance on convenient foods that are often high in sodium and low in nutritional value.

Hydration habits are additional concerns among office workers. Many professionals rely heavily on coffee, energy drinks, or sugary beverages during long workdays, often replacing plain water as the main source of fluid intake.

Protecting kidney health often begins with small lifestyle changes. Reducing processed food consumption, limiting excessive salt intake, staying adequately hydrated, and maintaining regular sleep schedules can all support kidney function.

Taking short movement breaks during long work hours and managing stress through regular physical activity or relaxation techniques may also help reduce the long-term strain that modern work routines place on the body.

Convenience foods have become the defining feature of urbanization. From ready-to-eat breakfasts to microwavable dinners and takeaway lunches, packaged food fits into all our lives.

But behind this convenience, what lies underneath are the tiny plastic particles, also referred to as microplastics, which are accentuating health concerns across the globe. Unknowingly, these microplastics are seeping through the plastic cutlery, food packaging, etc., potentially into our bodies. Plastics have been widely used for ages due to their higher affordability, durability, and extensive applications in various industries.

What Are Microplastics?

As per a recent literature quoted by Zhang et al. 2025, only about 20% of the plastic waste produced is recycled, whereas the rest is either abandoned in landfills or dispersed into the environment. Microplastics are the new emerging pollutant category in the modern era, raising prominent concerns in both health & environmental contexts. As per scientific literature, microplastics are plastic fragments with a diameter of less than 5mm.

Food Packaging Contributes to Microplastic Exposure

Plastic food packaging dominates the global food system, since it can be designed in any form (container, wrapper, pouch, etc) while keeping food fresh for longer periods.

Microplastics are released from food packaging(s), especially when they are exposed to prolonged heat, abrasive forces, and undue environmental stresses. Heating and/or reheating food in plastic containers or choosing to decant packaged food commodities in plastic containers and maintaining them under unfavorable circumstances can all increase the likelihood of microplastic release.

Bottled Water and Everyday Sources of Microplastics

Bottled water has also proven to release thousands of microplastic particles into the water they contain when exposed to sunlight/ heat. We never give a thought to such bottles being sold by the roadside vendors, wherein these plastic bottles are hung for indefinite days on that kiosk.

Those bottles are in constant light exposure all day without even pondering about the ill effects it may cause to the consumers. Similarly, single-use tea bags have also been shown to release billions of microplastics when steeped in hot water. These findings highlight a troubling paradox that products marketed for convenience and safety may be introducing new risks that consumers never thought about.

What Does Research Say About Health Risks?

The health implications of ingesting microplastics remain an active area of research, but early findings are enough to raise concerns. Studies have demonstrated microplastics in human blood, lungs, and even placental tissue. This suggests that upon ingestion, these particles may not simply pass through the body. Instead, they would accumulate in tissues or interact with biological systems in ways that are not yet fully explored.

One of the major health implications pertaining to microplastic ingestion is inflammation. These particles can trigger irritation in tissues, eventually impacting the immune responses.

Plastics often contain additives in the form of plasticizers, etc., which may disrupt hormone function and impair the normal cellular function.

Infants and children are more often vulnerable as their food is also packed in plastic packaging or containers (like plastic sippers, feeding bottles, baby food pouches, etc.), raising long-term exposure risk during critical stages of growth.

Steps to Reduce Microplastic Exposure

The issues relating to plastic usage also reflect a broader tension in the modern era, where convenience seems to intersect with health! For people or families juggling work and financial burdens, avoiding packaged foods mostly sounds unrealistic.

Still, some small and consistent actions can help us reduce the exposure to microplastics, like opting for glass or paper packaging wherever possible. Avoiding heating food in plastic containers or opting for biodegradable packaging options could prove to be beneficial in the future. Though microplastics are invisible to our naked eyes, what we do next to curb them would help us shape a healthy future.

Are you aware? Scientific insights are helping people of all ages understand heart health better and take the right steps at the right time. Heart health is no longer a concern only for older adults. So, people across all age groups are at risk of developing Heart Disease because of changing lifestyles, stress, and unhealthy habits.

So, here, science plays a pivotal role. With the help of improved research, advanced diagnostics, and increased awareness, science is helping individuals understand their risk factors early and take preventive steps before serious complications arise.

Heart Disease Can Begin Earlier Than You Think

Heart disease is commonly seen in people of all age groups. So, according to scientific research, heart disease develops gradually over time. Early markers such as high cholesterol, blood pressure, and poor lifestyle habits can begin affecting the body even in the 20s or 30s and lead to a poor quality of life.

Today, advanced screening tools and regular health check-ups make it possible to detect these risks early and initiate timely intervention.

Prevention Strategies

For youngsters, science tends to highlight the importance of prevention through healthy eating, regular exercise, quitting smoking, and alcohol. When it comes to middle-aged adults, monitoring conditions like diabetes, hypertension, and cholesterol can help save the heart.

In older adults, it will be necessary to manage existing conditions like diabetes and high blood pressure and prevent heart attacks or stroke.

How Technology Is Transforming Heart Care

Moreover, you will also have to understand that genetics also plays an important role. Scientific advancements help doctors identify individuals with a family history of heart disease and guide them with individualized treatment care plans for outcomes.

Currently, you will be surprised to know that modern science has also shed light on the importance of lifestyle in maintaining heart health. So, opting for wearable devices, health apps, and regular screenings helps track heart rate, physical activity, and prevent any concerning heart problems in people.

Robotic surgeries are now enabling heart patients to recover more quickly and provide benefits such as shorter hospital stays, minimal blood loss, and are extremely safe.

Hence, by understanding risk factors, adhering to healthy habits, and undergoing regular check-ups as advised by the doctor on a yearly basis, individuals can take control of their heart health.