Happiness is influenced by a complex interplay of various chemicals in our brain, particularly four key neurotransmitters, D.O.S.E or Dopamine, Oxytocin, Serotonin, and Endorphins. These chemicals, often referred to as "happiness chemicals," are responsible for creating feelings of joy, motivation, connection, and calm.

However, when there's a deficiency in any of these, it can significantly affect our mood, energy, and overall well-being. Let’s dive into what these four neurotransmitters are, how their deficiency impacts us, and how we can boost their levels naturally.

Dopamine: The Motivation and Reward Chemical

Dopamine is often called the "motivation molecule." It plays a major role in enabling motivation, learning, and the pleasure-reward system in the brain. When we accomplish something — whether it’s finishing a project, completing a workout, or achieving a goal — dopamine gives us that sense of satisfaction and determination to continue.

Deficiency Effects:

When dopamine levels are low, it can lead to procrastination, low self-esteem, lack of focus, and general fatigue. A person might feel anxious, hopeless, or experience mood swings because the brain isn’t getting the reward signals it needs.

Boosting Dopamine:

You can increase dopamine levels by setting and achieving small goals, exercising regularly, eating foods rich in L-Tyrosine (such as almonds, avocados, and eggs), and practicing mindfulness or meditation. Engaging in creative activities like writing or drawing also helps boost dopamine levels.

Oxytocin: The Bonding Chemical

Oxytocin is often referred to as the "love hormone" or "cuddle hormone" because it plays a major role in social bonding and trust. It’s released when we hug, touch, or engage in other forms of physical affection. Oxytocin fosters feelings of connection and emotional intimacy, making it essential for relationships, family bonding, and even team cooperation.

Deficiency Effects:

A lack of oxytocin can lead to feelings of loneliness, stress, anxiety, and difficulties in forming or maintaining relationships. Low oxytocin levels are associated with feelings of isolation and disconnection from others.

Boosting Oxytocin:

You can raise your oxytocin levels through physical touch, socialising, spending quality time with loved ones, and even engaging in activities like massage or listening to soothing music. Acts of kindness, such as helping others or volunteering, also help release oxytocin.

Serotonin: The Mood Stabiliser

Serotonin is responsible for feelings of well-being and contentment. It helps regulate mood, sleep, digestion, and even social behavior. People who have balanced serotonin levels often feel calm, confident, and emotionally stable. Serotonin is crucial in helping people feel valued and significant among their peers.

Deficiency Effects:

Low serotonin levels are linked to depression, low self-esteem, irritability, and mood swings. Individuals may feel overly sensitive to criticism, experience panic attacks, or struggle with social phobias when serotonin is deficient.

Boosting Serotonin:

You can boost serotonin by getting regular exercise, exposing yourself to sunlight, engaging in cold showers or massages, and practicing mindfulness. Simple activities like walking in nature, meditating, or doing yoga are also effective serotonin enhancers.

Endorphins: The Pain Reliever

Endorphins are the body’s natural painkillers. Released in response to stress, pain, or intense physical activity, they help alleviate discomfort and promote a sense of euphoria. Endorphins are what make you feel good after a workout or a hearty laugh, often referred to as the "runner's high."

Deficiency Effects:

Without enough endorphins, people may experience anxiety, depression, chronic pain, and insomnia. A deficiency in endorphins can make daily life feel overwhelming and physically draining.

Boosting Endorphins:

To boost endorphins, engage in laughter, exercise, and stretching activities. Eating spicy foods or dark chocolate can also stimulate endorphin production. Regular massage therapy and meditation are other ways to naturally elevate endorphin levels.

A growing body of global research is beginning to point in one direction: our eyes are under strain like never before. As per the report published on PubMed, myopia is projected to rise significantly worldwide, increasing from about 27% of the global population in 2010 to nearly 52% by 2050, highlighting its emergence as a major public health concern.

Although genetics has long contributed, there appears to be a significant environmental factor associated with how fast this shift has occurred.

Screens have become an integrated part of everyday lives, from the time of waking up to work on digital screens or scroll through phones late into the night. Digital devices are no longer optional but a constant priority.

Work, education, and entertainment are all now done on screens with little or no interruption. The growing generation of gadgets has its own advantages, but its impact has significantly contributed to the alarming rise in cases of myopia.

The Science Behind the Surge: Why Our Eyes Are Struggling

There are three major significant ways prolonged screen time could affect vision:

• Near Vision strain - Prolonged near-vision focus places a constant strain on the eye muscles, causing them to remain contracted. This will eventually lead to elongation of the eyeball and myopia.

• Reduced Blinking due to dry eyes - Screen use decreases the rate of blinking, which causes the eyes to dry out, leading to irritation and instability.

• Lack of Sunlight - Less time outdoors reduces the opportunity to receive sunlight. Sunlight exposure is especially important in children for proper vision development.

From Temporary Strain to Long-Term Damage

Mild discomfort, such as dryness, headaches, and blurred vision, can lead to more chronic issues. Digital eye strain is common among adults and children alike. However, the long-term outcome is the main concern.

Progressive myopia increases the chances of developing serious eye diseases like glaucoma, retinal detachment, and macular degeneration, and having to wear stronger prescription glasses. These aren't just short-term inconveniences; they can create lifelong risks that severely affect the quality of life.

The Post-Pandemic Effect: A Generation at Risk

The days when children spent their time flying kites, playing marbles, feeling the wind on their faces, and returning home with dust-covered hands have gradually faded into memory. The COVID-19 pandemic accelerated an already existing trend.

The screen time increased as many schools transitioned to online education and remote workers increased due to the pandemic. Above all, children experienced a sudden reduction in outdoor activity with increased exposure to digital devices.

The phase indicated a noticeable drop in the vision of the people. This period has often been referred to as a phase of “quarantine myopia,” where many young individuals reported a noticeable decline in vision.

As individuals return to normalcy, the habits that were established are continuing, and concern is being raised about a generation having poorer visual health.

Prevention Over Cure: Rethinking Visual Hygiene

Consistent habits are needed to address this issue:

• 20-20-20 rule: After every 20 minutes of looking at a digital device with stress, try to look at something far away (at least 20 feet away) for approximately 20 seconds to relax your eye muscles and reduce the stress placed on your eyes.

• Limit recreational screen time: Reducing the amount of time spent using screens will help reduce the likelihood of developing eye strain and progression of myopia, especially in children.

• Proper viewing distance and posture: Keeping screens at approximately one arm's length will help to minimise the amount of stress placed on your eyes and body.

• Encourage Outdoor Activity: Children between the ages of 6 and 16 years should be encouraged to engage in outdoor activities more frequently and not replace books with tablets or iPads.

• Mandatory Vision Screening: Vision screening and eye check-ups prior to school admissions should be made mandatory by the government, as early detection of myopia can help prevent further complications.

A Call for Collective Responsibility

The increase in use of screens is not an isolated event; it is part of the larger trend affecting how we live and work. To address this issue, we need to develop awareness among individuals, families, schools, and workplaces about proper screen use. A balanced daily routine, guided by parents, plays a crucial role in maintaining healthy vision in children.

Collective responsibility among teachers, parents, and government authorities is essential to prevent visual complications, as children represent our future generations. Greater public awareness around digital eye strain and eye health is also necessary, as it often serves as a precursor to multiple health complications.

Eye health must be seen as an essential part of overall well-being. The current trend may still be a developing issue, but it requires urgent attention. Acting early, with informed choices and preventive care, can ensure that technological progress does not come at the cost of long-term vision health.

Persistent hip pain is often dismissed as a muscle strain, poor posture, or fatigue. However, doctors warn that ongoing pain in the hip could sometimes be a signal for avascular necrosis (AVN) or osteonecrosis. This is a condition where reduced blood supply causes bone tissue to die. It may eventually lead to the collapse of the hip joint and serious mobility issues.

What Is Avascular Necrosis?

Avascular necrosis occurs when blood flow to a bone is interrupted or significantly reduced. The condition most commonly affects the hip joint, especially the femoral head (the rounded top portion of the thigh bone that fits into the hip socket). Over time, a lack of blood supply weakens the bone and may cause damage to the joint.

Early Symptoms Often Go Ignored

One of the biggest challenges with it is that symptoms appear gradually. In the early stages, people may only notice mild discomfort in the groin or hip area. As the disease progresses, pain may become more persistent. It can even worsen walking, climbing stairs, or standing for long periods. Some patients might eventually experience pain even while resting.

Who Is at Higher Risk?

Several factors can increase the likelihood of developing AVN. Long-term steroid use, excessive alcohol, hip injuries, fractures, and certain medical conditions such as lupus and sickle cell disease are known risk factors.

Delayed Treatment Can Lead to Joint Collapse

If AVN continues to progress, the weakened bone may eventually collapse. This can lead to severe arthritis and chronic pain. In advanced stages, patients may struggle with everyday activities such as walking, bending, or even standing for extended periods. Doctors say delayed diagnosis is one of the biggest reasons many patients require joint replacement surgery later.

Why Early Diagnosis Matters

Early diagnosis is crucial because treatment works best before the bone collapses. MRI scans and imaging tests can help detect the condition in its early stages. Treatment may include medications, physical therapy, or surgery in advanced cases. Early medical attention may help preserve the joint and prevent permanent damage.

Higher temperatures in the US could increase heat-related heart disease by 200 per cent by 2050, according to an alarming study.

The research, published in JAMA Cardiology, predicts rising temperatures driven by climate change will dramatically increase heat-related heart disease in the US.

It is already known that extreme heat is detrimental to heart health and can potentially trigger heart attacks and other cardiovascular events.

"But this study is the first to map out exactly how bad the problem could get—county by county, across the US. It also highlighted how states with lower median household incomes are likely to face higher heat-related heart disease burden," said Gokul Parameswaran, research associate at the Case Western Reserve School of Medicine's Cardiovascular Research Institute and the study's lead author.

Regional Hot Spots

Researchers analyzed heart disease data in each county in the contiguous US from 2010 to 2016 to develop projections through 2050.

They found that the Pacific Northwest has the highest heat-related heart disease rate in the country. Southern states, however, are projected to see the steepest increases by 2050.

"Climate change is not just an environmental issue—it is a health equity crisis, and prioritizing vulnerable communities must be at the center of any heat mitigation strategy," said Salil Deo, associate professor in the Department of Surgery.

Also read: Global Temperatures Likely To Stay Near Record Levels For Next Five Years: WMO

The study also found that aging — independent of temperature increases — will contribute an additional 34 per cent increase in heat-related heart disease by 2050, simply because there will be more older adults by then.

Heat Events In The US

The study comes amidst more frequent heat events in the US, which is also lasting longer, and the temperatures during heat events are going up.

The past 10 years, from 2015 to 2024, were the hottest on record globally. But in cities across the United States, the average rate of extreme heat events increased from two per year in the 1960s to 10 per year between 2010 and 2020, according to Center for Climate and Energy Solutions (C2ES), a Washington-based NGO.

Also Read:‘Heat Dome’ Triggering Record-Breaking May Temperatures In France, UK, Spain

Additionally, as of 2024, the average length of heat-wave season in the US has increased by 46 days since the 1960s.

How Does Heat Raise Heart Risks?

According to the Centers for Disease Control and Prevention, when temperatures rise, the heart must work harder to keep the body cool, and the likelihood of developing sudden clots in the bloodstream increases.

Read More: Can Extreme Heat Trigger Heart Palpitations? Expert Explains Risks

This extra stress on the heart due to high heat may lead to heart attacks or sudden worsening of heart disease, especially in the elderly or those with prior heart conditions.

How To Tackle The Risk

• Expanding green spaces and tree cover in urban areas could help reduce temperature-related adverse effects.
• Expanding access to cooling centers and air-conditioning assistance programs for low-income communities can also help bridge the gap in underserved communities.

"Climate change is not a distant, abstract threat," said Sanjay Rajagopalan, director of the Cardiovascular Research Institute and chief of Cardiovascular Medicine at University Hospitals Harrington Heart & Vascular Institute.

"It is a present and growing danger to the hearts of every American, and it is coming for the most vulnerable among us first. The choices made today about greenhouse gas emissions, urban planning, and health care policy will determine whether tens of thousands of Americans live or die from heat-related heart disease by 2050," he added.