How to Fall Back Asleep After Waking Up In Middle Of The Night

Updated Mar 10, 2025 | 03:00 AM IST

SummaryBut there are ways to help your body relax and drift off again without too much effort. Here are ten evidence-based strategies that could help you get the rest you need.
How to Fall Back Asleep After Waking Up In Middle Of The Night

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Waking up in the middle of the night can be frustrating—especially when you struggle to fall back asleep. But there are ways to help your body relax and drift off again without too much effort. Here are ten evidence-based strategies that could help you get the rest you need.

1. Block out disruptive noises

If a disturbing sound outside your window wakes you, try shutting it to block it out. You might also try using earplugs, turning on a fan, or listening to white noise. A 2021 research review found that white noise may improve sleep in some individuals, though results were mixed and more studies are needed.

2. Leave your bed

Try moving into a different room if you haven’t fallen asleep in 15 minutes. Then do something relaxing to distract your mind for a few minutes. This may make it easier to fall asleep when you return to bed.

3. Avoid staring at the clock

Staring at the clock may make you feel anxious about not sleeping. You might even consider getting rid of your alarm clock completely. Research published in 2019 suggests that anxiety and trouble falling asleep are associated. People who manage anxiety often worry about falling asleep, and people who have difficulty falling asleep often feel anxious.

4. Avoid screens

Turn off all your devices. Notification sounds may awaken you. Smartphones and other electronics also emit blue light that may suppress your body’s melatonin production. Melatonin is a hormone that helps regulate your circadian rhythm and sleep cycles. Blue light-blocking glasses are an inexpensive option that may improve sleep, according to a 2021 research review, but research is mixed.

5. Meditate or try breathing exercises

A 2018 research review on the effect of mindfulness meditation indicates breathing exercises or meditating may help treat some aspects of sleep disturbance and improve sleep quality. One useful method is the 4-7-8 breathing technique: inhale through your nose for 4 seconds, hold your breath for 7 seconds, then exhale through your mouth for 8 seconds.

6. Relax your muscles

One technique that some people may find helps them relax and sleep is performing a full body scan. Close your eyes, breathe slowly, and move your attention from your face down to your feet, relaxing each area as you go.

7. Sleep with the lights off

Resist the temptation to turn on the lights, even if you get out of bed. Bright light may interfere with your body’s melatonin production and wake you up.

8. Focus on something boring

Research from 2018 found that many people report feeling sleepy when bored. The classic “counting sheep” technique — or any uninteresting task that occupies your mind — may help distract you and make falling asleep easier.

9. Listen to relaxing music

Relaxing music may help calm your mind and block sounds that may disrupt your sleep. Personal preference plays a large role in determining what type of music is best, so experiment with different styles.

10. Try sleep apps

Sleep apps offer relaxing stories, music, and sounds. Apps like Calm and Headspace offer free trials, allowing you to see what works best for you.

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Combining GLP-1 & Hormone Therapy During Menopause? Know About Its Benefits And Side Effects

Updated Aug 12, 2026 | 07:00 PM IST

SummaryA recent study has observed that menopausal women who took GLP-1 drugs and hormone therapy together could lose more weight.
Combining GLP-1 & Hormone Therapy During Menopause? Know About Its Benefits And Side Effects

Credit: AI

For many women, menopause can bring a string of uncomfortable symptoms like hot flashes, sleep problems, changing body composition and weight gain.

Now, researchers are looking at whether combining GLP-1-based weight-loss medicines with menopausal hormone therapy (MHT) could offer greater benefits, particularly for women struggling with obesity after menopause.

A recent Mayo Clinic study, published in The Lancet Obstetrics, Gynaecology & Women's Health, found that postmenopausal women taking tirzepatide along with hormone therapy lost about 35% more weight than those taking tirzepatide alone.

What Are The Study's Findings?

Researchers studied 120 postmenopausal women with overweight or obesity who had been taking tirzepatide for at least 12 months. Forty women were also using MHT, while 80 were not.

Women taking both treatments lost around 17-19% of their body weight, compared with about 14% among those taking tirzepatide alone. About 45% of women on the combination achieved at least 20% weight loss, compared with 18% in the tirzepatide-only group.

“This study provides important insights for developing more effective and personalized strategies for managing cardiometabolic risk in postmenopausal women,” said Dr Regina Castaneda, first author and Mayo Clinic researcher.

However, this was just an observation in the study, not a randomized clinical trial. Therefore, it cannot prove that hormone therapy itself caused the additional weight loss.

“It is possible that women using hormone therapy were already engaged in healthier behaviors, or that menopause symptom relief improved sleep and quality of life,” said Dr Maria Daniela Hurtado Andrade, senior author of the study.

Also read: Postmenopausal Women May Face More Severe Dry Eye Disease; How Do Hormones Contribute?

Could The Combination Work?

During menopause, declining oestrogen levels can change fat distribution, appetite, metabolism and muscle mass. GLP-1 medicines, meanwhile, reduce appetite and slow stomach emptying, helping with weight management.

Researchers believe there could also be a biological interaction between oestrogen and GLP-1 signalling. “Preclinical data suggest a potential synergy, with estrogen appearing to enhance the appetite-suppressing effects of GLP-1,” Castaneda said.

Earlier research has also suggested greater weight loss among postmenopausal women using semaglutide alongside hormone therapy.

A 2026 review similarly concluded that GLP-1 medicines may help reduce weight and abdominal fat in menopausal women, but larger studies are needed.

Also read: Experimental Menopause Drug Shows Promise Mid-Stage Trial, Reduces Hot Flashes By 83%

Are There Any Side Effects Of Combining These Drugs?

GLP-1 medicines may cause nausea, vomiting, diarrhoea, constipation, abdominal pain and reduced appetite. These effects often surface when the dose is increased.

Hormone therapy has its own side-effects and it is also not suitable for everyone. Depending on the patient's medical history, MHT can increase the risk of complications like blood clots and stroke.

Hormone therapy should not be started simply to fuel weight loss from a GLP-1 drug. It is primarily used to treat certain menopause symptoms and should be prescribed after considering a woman's age, symptoms, medical history and individual risks.

As Hurtado Andrade noted, researchers now want to determine whether the combination offers benefits beyond weight loss, including improvements in cardiometabolic health.

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Why Your Thyroid Test Results Can Vary Between Labs?

Updated Aug 12, 2026 | 03:00 PM IST

SummaryThyroid test results can vary between laboratories due to differences in testing methods, equipment, reference ranges, and sample handling, without necessarily indicating a change in thyroid function.
Why Your Thyroid Test Results Can Vary Between Labs?

Credit: AI

It can be confusing and sometimes alarming to receive different thyroid test results from two different laboratories, especially when both tests are done on the same day. A slight difference in values does not necessarily mean that your thyroid function has suddenly changed. In many cases, the variation is due to differences in how the tests are performed rather than a change in your health.

The Laboratory Can Make A Difference

One of the biggest reasons for varying results is the laboratory itself. Accredited laboratories, such as NABL-certified labs, follow stringent quality-control measures, use standardised testing protocols and have trained personnel to handle samples correctly. Laboratories with less rigorous quality standards may produce results that are less consistent.

Different Equipment Can Produce Different Results

The equipment and testing methods used can also differ from one laboratory to another. Different analysers, calibration techniques and testing kits can produce slightly different values for thyroid hormones such as TSH, T3, T4, Free T3 and Free T4.

Even the reference ranges printed on reports may not be identical because each laboratory establishes its own normal range based on the equipment used and the population it serves.

Also read: UK Approves Eli Lilly’s Foundayo: Is the GLP-1 Pill Better Than Wegovy, Mounjaro?

The Time Of Your Test Matters

The timing of the test is another important factor. Thyroid-stimulating hormone (TSH) naturally fluctuates throughout the day. It is generally higher during the early hours of the morning and gradually falls as the day progresses.

As a result, a blood sample collected in the afternoon may show a lower TSH level than one collected early in the morning.

Stress, Sleep And Medication Can Affect Results

Lifestyle and biological factors can also influence thyroid hormone levels. Stress, poor sleep, recent illness, medications and even eating before the test may affect the results.

For people taking thyroid medication, blood samples should ideally be collected in the morning on an empty stomach and before taking the daily dose. Testing after medication may temporarily alter hormone levels and make interpretation more difficult.

Also read: Why Women Want Hormonal Health Care, Not Just Pregnancy Care

Biotin And Other Medicines Can Interfere With Thyroid Tests

Certain supplements and medications can interfere with thyroid tests as well. Biotin, commonly found in hair and nail supplements, can falsely lower TSH levels while increasing Free T3 and Free T4 values.

Medications such as amiodarone, glucocorticoids, dopamine and heparin may also affect thyroid hormone measurements. During pregnancy, hormonal changes, particularly increased levels of human chorionic gonadotropin (hCG), can naturally alter TSH values.

Even Sample Handling Can Affect The Report

Laboratory handling also plays a role. Delays in processing, improper storage temperatures, differences in centrifugation timing or sample-handling errors can influence the final result.

In some individuals, thyroid autoantibodies may interfere with laboratory assays, potentially leading to inaccurate Free T3 and Free T4 measurements.

Also read: Silent Neck Swellings: Why An Unusual Lump Should Never Be Ignored

Should You Repeat A Thyroid Test?

Because of these variables, experts recommend getting thyroid tests done at the same accredited laboratory whenever possible. This allows doctors to compare results more reliably over time.

If a thyroid value is only mildly abnormal or falls within a borderline range, it may often be advisable to repeat the test before making a diagnosis or starting lifelong medication.

Ultimately, thyroid test reports should never be interpreted in isolation. Doctors consider the patient's symptoms, medical history, physical examination and repeat test results before deciding on treatment.

Consistency in where and how the test is performed can help avoid unnecessary anxiety and support more accurate clinical decisions.

By Dr Shaheen Guy, General Physician, Saifee Hospital, Mumbai

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Beyond the Hype: What Patients Should Really Know Before Choosing Robotic Surgery

Updated Aug 12, 2026 | 11:13 AM IST

SummaryRobotic surgery offers greater precision and minimally invasive benefits, but patients should understand its risks, limitations, costs, alternatives, and the surgeon’s expertise before making a decision.
Beyond the Hype: What Patients Should Really Know Before Choosing Robotic Surgery

Credit: AI

Robotic surgery has rapidly become one of the most talked-about advances in modern medicine. Yet, for many patients, the technology remains misunderstood.

The first thing to know is that the robot does not perform the operation. Every movement is directed by the surgeon. The robotic platform translates the surgeon’s hand movements into highly precise, tremor-filtered movements inside the body while providing magnified three-dimensional vision and greater instrument dexterity.

The real question, therefore, is not whether robotic surgery is better. It is whether it is the right choice for a particular patient, procedure and surgeon.

Where Robotic Surgery Can Make A Difference?

For many routine operations, conventional laparoscopy may achieve equally good outcomes. Technology should support clinical judgment, not replace it.

Patients should also recognise that outcomes depend far more on the experience of the surgical team than on the robotic system itself. Successful robotic surgery requires specialised training, structured credentialing and a coordinated operating theatre team.

Choosing an experienced surgeon can therefore be more important than choosing a hospital simply because it owns a robotic system.

Also read: 18-Year-Old In Critical Condition After Acidic Substance Allegedly Given Instead Of Anaesthetic During Surgery

Making Robotic Surgery More Accessible

Another important development is that robotic surgery is becoming more accessible. Indigenous platforms are helping expand advanced surgical care beyond a handful of metropolitan hospitals by making robotic programmes more viable for a wider range of healthcare institutions.

This gradual decentralisation means patients in Tier II and Tier III cities can increasingly access advanced minimally invasive surgery closer to home, reducing the need to travel long distances for specialised treatment.

Also read: Osteoporosis Drugs Offer New Hope For Back Pain By Blocking Disc Mineralisation: Study

Could Robotic Surgery Work Across Long Distances?

Innovation is also extending beyond the operating room. Robotic telesurgery, demonstrated successfully using Made-in-India robotic platforms, has shown that expert surgeons can operate across vast distances using secure digital networks.

While widespread adoption will require robust infrastructure and regulatory frameworks, the technology represents an important step towards improving access to specialised surgical expertise.

Also read: Surgeon Barred From Practice After Connecting Wrong Parts of Patient’s Bowels During Emergency Surgery

What Should Patients Ask Their Surgeon?

Patients should look beyond the hype and ask informed questions:

  • Is robotic surgery appropriate for my condition?
  • What experience does my surgeon have with this procedure?
  • What are the expected benefits?
  • What are the limitations and risks?
  • Would conventional laparoscopy or open surgery be equally suitable?

With indigenous platforms helping decentralise robotic surgery, advanced care is becoming more accessible beyond major metros. The technology has also demonstrated the potential of interhospital telesurgery, enabling expert surgeons to operate across distances and potentially helping bridge gaps in access to highly skilled surgical expertise.

Ultimately, the future of surgery will not be shaped by machines alone. It will be shaped by skilled surgeons using intelligent technology to deliver safer, more precise and equitable patient care.

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