A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

• Heart
• Blood vessels
• Liver
• Immune system
• Pancreas
• Kidneys
• Lungs
• Intestines
• Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

Gait, or an individual's walking pattern, is an important marker of overall health, reflecting neurological integrity, musculoskeletal function and cognitive status. Although walking may seem effortless, people often dismiss changes in their gait as signs of tiredness or ageing.

Losing balance while walking can sometimes be attributed to fatigue, dehydration or a momentary lapse in attention. However, recurrent or unexplained balance problems can also indicate an underlying neurological condition and should not be ignored, experts warned.

Dr Gaurav Batra, Principal Consultant, Neurosurgery, Yashoda Super Speciality, said individuals experiencing instability, changes in their walking pattern or more frequent tripping than usual should seek medical evaluation.

"Walking seems so natural that it is often taken for granted. However, it involves the brain, nerves, muscles, eyes and the balance system in the inner ear working in unison," he told HealthandMe.

"When there is a disorder in one of these systems, the way a person walks can be affected, which is exactly why the type of imbalance becomes an important consideration. One person may feel like they are being dragged in a particular direction," the expert added.

When Is Loss Of Balance A Neurological Warning Sign?

New, persistent or worsening balance problems warrant attention, Dr Batra said. Changes in walking patterns or deteriorating balance could sometimes indicate an underlying problem affecting the brain or spinal cord.

Certain conditions can cause pressure on the brain or spinal cord in the neck, resulting in subtle changes in walking patterns and the ability to maintain balance.

Dr Batra advised against dismissing increasingly abnormal changes in walking, particularly when they affect daily activities or occur alongside stiffness, tremors, weakness, numbness or difficulty with coordination.

Neurological Conditions That Can Affect Balance

Dr Atampreet Singh, Senior Director and Head, Institute of Neurosciences, ShardaCare - Healthcity, explained that disruptions in the systems responsible for maintaining balance can cause unsteadiness, difficulty walking in a straight line, frequent stumbling and an increased tendency to fall.

Recurrent balance problems may be associated with several neurological conditions, including:

• Parkinson's disease: Can affect movement and coordination, making walking and maintaining balance difficult.
• Cerebellar disorders: Can interfere with coordination and the ability to maintain a steady gait.
• Peripheral neuropathy: Damage to peripheral nerves can affect sensation and balance.
• Multiple sclerosis: Can disrupt communication between the brain and the rest of the body, affecting coordination and walking.

In older adults, recurrent or unexplained falls may sometimes be an early indication of an underlying neurological or sensory deficit, Dr Singh told HealthandMe.

Sudden Loss Of Balance Could Indicate A Stroke

A sudden loss of balance, particularly when accompanied by other neurological symptoms, can be a warning sign of stroke and requires immediate medical attention.

Dr Singh highlighted the following symptoms to watch for:

• Weakness or numbness on one side of the body
• Facial weakness
• Difficulty speaking
• Severe dizziness
• Visual disturbances
• A sudden, severe headache

Such symptoms require immediate medical assessment, the expert noted.

When Should You See A Doctor?

Seek medical attention if unsteadiness persists or worsens, particularly when accompanied by weakness or numbness in the arms or legs, frequent falls, severe headache, vomiting, changes in vision or speech, or loss of bladder or bowel control.

A doctor may conduct a neurological examination and recommend brain or spinal imaging, if necessary, to determine the cause.

The doctors noted that early diagnosis is important because some underlying conditions are treatable, and timely intervention may help prevent permanent neurological problems.

They advised patients to pay attention to when the imbalance began, whether it appeared suddenly or developed gradually, and whether it is accompanied by tremors, dizziness, numbness, weakness, speech changes or difficulty with coordination.

When we talk about cancer prevention, the conversation usually turns to individual choices. Whether someone smokes, what they eat, how much they exercise, or how regularly they visit a doctor. These are important considerations, but they do not tell the whole story. A person's surroundings can influence their health in ways that are not always immediately apparent. The air they breathe every day, the conditions in which they work, the food they can afford and the healthcare available to them can all have a bearing on their risk of developing cancer.

In clinical practice, cancer rarely has one identifiable cause. It develops through a combination of factors, including age, genetics, infections, lifestyle and environmental exposure. Some of these can be modified. Others are tied to circumstances that people have little control over.

The air we breathe and the work we do

Air pollution is generally discussed in the context of respiratory and cardiovascular illness. Its association with cancer, particularly lung cancer, deserves equal attention. Fine particulate matter from vehicle exhaust, industrial emissions, construction dust and waste burning can remain in the air people breathe over long periods. Indoor air quality is another concern. In homes where wood, coal or other biomass fuels are used for cooking, poor ventilation can expose families to harmful smoke over many years.

The workplace presents a different set of risks. Construction workers, miners and employees in certain manufacturing industries may regularly come into contact with substances such as asbestos, silica dust and diesel exhaust. Prolonged exposure to these carcinogens is associated with specific cancers. The risk is not simply a matter of the nature of the job, but also the conditions under which it is performed. Protective equipment, adequate ventilation and routine workplace monitoring are therefore essential, not optional safety measures.

What ends up on the plate is not always a choice

Diet is another area where personal circumstances matter. What a person eats is influenced by affordability, availability, working hours and household responsibilities. A consistently poor dietary pattern, particularly one high in processed meat and low in fibre, is associated with an increased risk of certain cancers. Excess body weight is also linked to several cancers, including colorectal, endometrial and postmenopausal breast cancer.

This does not mean that eating a particular food will cause cancer, or that avoiding one ingredient will prevent it. The concern is with patterns that develop over time, alongside other risk factors. Advising people to eat better is only useful when that advice considers what they can realistically afford and access.

Why some communities face greater challenges

The same health advice does not translate into the same opportunities for everyone. People living in congested neighbourhoods may have limited control over their exposure to pollution. Workers in informal or unregulated sectors may not have access to adequate protective equipment or occupational health services.

These circumstances can also determine how quickly someone receives a diagnosis. A persistent cough, unexplained weight loss, a breast lump or unusual bleeding may initially be dismissed. For someone who has to travel long distances, lose a day's wages or pay out of pocket for investigations, seeking medical attention is not always straightforward. By the time they reach a specialist, the disease may have progressed.

Early detection, therefore, is not just about recognising symptoms. It also depends on whether people can access a doctor, undergo the necessary investigations and complete their follow-up care.

Prevention has to go beyond individual choices

There are established ways to reduce cancer risk. Avoiding tobacco, limiting alcohol, maintaining a healthy weight and staying physically active all matter. HPV and hepatitis B vaccination can help prevent cancers associated with these infections. Screening for breast, cervical and oral cancers should be undertaken as recommended, based on age and individual risk. A persistent or unusual symptom should always be evaluated rather than left unattended.

But prevention cannot stop at the doctor's consultation room. Cleaner air, safer workplaces, better housing and affordable diagnostic services need to be part of the larger conversation.

A person's risk of cancer is shaped by more than the choices they make. It is also influenced by the conditions in which they live, work and seek care. Recognising this is important because prevention becomes meaningful only when people have a fair opportunity to act on it.

(Dr Rajesh Shinde - Director – GI (HPB–Colorectal) & Thoracic Surgical Oncology, Apollo Cancer Centre, Western Region, Apollo Hospitals)

Winter brings a significant rise in respiratory problems, particularly among people living with asthma. Increased air pollution, falling temperatures and exposure to dust and other airborne irritants can trigger inflammation in the airways, leading to symptoms such as coughing, wheezing, chest tightness and breathlessness.

While these factors can make asthma more difficult to manage, many patients also make treatment-related mistakes that can worsen their symptoms and increase the risk of an asthma attack.

One of the most common mistakes is discontinuing inhalers when symptoms improve. Asthma is a chronic inflammatory condition, and the absence of symptoms does not necessarily mean that the underlying inflammation has resolved. Controller inhalers, particularly those containing inhaled corticosteroids, help reduce airway inflammation and prevent flare-ups.

Stopping these medications without medical advice can leave patients vulnerable to sudden exacerbations, especially during periods of high pollution.

Another concern is the excessive reliance on rescue inhalers. These inhalers provide quick relief by relaxing the muscles around the airways, but they do not necessarily address the underlying inflammation. Frequent use may indicate that asthma is not adequately controlled and that the patient's treatment plan needs to be reviewed by a doctor. Patients should not increase their medication dosage or frequency without appropriate medical guidance.

Incorrect inhaler technique is another frequently overlooked problem. Patients may use their inhalers too quickly, fail to coordinate inhalation with medication release or neglect to hold their breath briefly after inhaling. These mistakes can prevent the medicine from reaching the lungs effectively. Regularly reviewing inhaler technique with a healthcare professional and using a spacer, where recommended, can significantly improve drug delivery.

Many patients also underestimate the importance of continuing their prescribed treatment during symptom-free periods. Some turn to steam inhalation, home remedies or over-the-counter cough medications instead of following their asthma management plan. Although certain supportive measures may provide comfort, they cannot replace prescribed asthma medication. Hot steam can also cause burns and should not be used as a treatment for asthma.

During winter, patients should monitor local air quality, reduce prolonged outdoor exposure when pollution levels are high, avoid tobacco smoke and other respiratory irritants, and keep their prescribed medication accessible. Wearing a well-fitting mask outdoors may help reduce exposure to particulate pollution, although it does not eliminate the risk.

Most importantly, people with asthma should have an individualised asthma action plan and attend regular follow-ups. Worsening breathlessness, difficulty speaking in full sentences or symptoms that do not respond to the prescribed reliever require urgent medical attention. With correct inhaler use, consistent treatment and timely medical review, most patients can manage their asthma more effectively even during highly polluted winter months.

(By Dr. Arunachalam M, Sr. Consultant and HOD-Pulmonology, Yatharth Super Speciality Hospital, Noida)