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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
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Naturopath and health educator Barbara O'Neill believes many of the foundations of good health are simple, inexpensive, and often overlooked.
In an interview with HealthandMe, she spoke about her journey into natural healing. Barbara said her interest began when she was looking for alternatives to repeated medication use for her children.
"I was pulled towards natural healing because I didn't want to give my children drugs," she said, recalling how her first child underwent four courses of antibiotics within six weeks.
That experience prompted her to explore other ways of managing common health issues such as earaches and discomfort.
Barbara said she sees similarities between her philosophy of health and Ayurveda. "I believe that there's a lot of similarities between what I believe," said the 72-year-old, adding that she supports approaches that work and do not cause harm.
While acknowledging that medicines can save lives in emergencies, she argued that long-term healing depends on creating the right conditions for the body.
"Yes, in a crisis, a drug may save a life, but drugs can't heal us. That's why it's time to go back to the old ways," she said.
According to Barbara, understanding how the body functions is key to understanding healing.
"When you understand how they function, then you begin to understand what they need. And if you give the body the right conditions, the healing will accelerate," she told HealthandMe.
Barbara said that sleep, hydration, exercise, and natural foods are key to better health. She also called out modern lifestyles, which often encourage people to stay awake too late, particularly because of technology; and recommended getting enough sleep.
"Start going to bed earlier and aiming for eight hours sleep a night," she said.
Barbara also emphasized daily movement, whether through running, walking, push-ups, squats, or stretching.
"Every day, I make a point of moving my body," she said.
At a time when supplements have become a multi-billion-dollar industry, Barbara revealed that she does not take any supplements herself.
"I take no supplements," she said, noting that she advocates focusing on fundamental health habits.
"What should be there instead is exercise every day, eating food in its natural state, drinking adequate water, and going to bed early," she said.
While she is not opposed to supplements, she believes they are often unnecessary.
"There are times where they may be necessary, but most of the time we don't need them," she added.
Barbara also encouraged people to eat foods in their natural state and suggested a simple dietary habit for Indians.
"Eat dal every day," she said.
For stress management, she said both sleep and meditation are important. She described beginning each day with prayer, reflection, and quiet time.
Barbara said that the human body has an innate ability to heal when supported by healthy habits.
"I want people to remember that they live in a body that can heal. So please look after it," she told HealthandMe.
Stress and long working hours can worsen preeclampsia in women. (Photo credit: AI generated)
Many working women who are pregnant tend to dismiss signs such as headaches, swelling, or vision changes, thinking that they are common during pregnancy. However, these issues can be caused by preeclampsia, a serious condition that requires timely attention, especially among busy working women.
Dr Prachi Sarin Sethi, Senior Consultant – Obstetrician, Gynaecologist & Laparoscopic Surgeon, Motherhood Hospitals, Gurgaon, said, "Pregnancy comes with many physical changes, and it is common for women to experience discomfort such as swelling, fatigue, or headaches. However, sometimes these symptoms may point to something more serious, namely preeclampsia, a pregnancy-related condition that can affect both the mother and baby. Working women tend to ignore the signs of this condition and struggle in silence. Preeclampsia is a condition that usually develops after the 20th week of pregnancy. It is mainly characterised by high blood pressure and can affect organs such as the liver and kidneys. If not managed in time, it can lead to serious complications for both mother and baby."
The exact cause of preeclampsia is not known. Certain factors increase the risk, including:
Many symptoms of preeclampsia are mistaken for normal pregnancy changes. These include:
Working women may ignore these signs due to work pressure, long hours, or frequent travel, assuming they are just tired or stressed. If left untreated, preeclampsia can lead to serious complications such as:
Early detection and proper care can help manage the condition and reduce risks.
This is why working women miss the signs
In today’s fast-paced lifestyle, many women continue working through pregnancy without slowing down. Long working hours, stress, irregular meals, and lack of rest tend to worsen symptoms. Many women delay check-ups or ignore warning signs, thinking they are minor issues.
Report any signs and symptoms, such as headaches and vision changes, to a doctor. De-stress by practising yoga and meditation. Monitor blood pressure regularly, avoid overexertion, and maintain a balanced diet consisting of fresh fruits, vegetables, whole grains, and pulses. Avoid junk, oily, and canned foods. It is also necessary to stay hydrated, attend regular health check-ups, and follow-up appointments.
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Osteoarthritis (OA), long considered a “wear-and-tear” disease of old age, is increasingly being diagnosed in people as young as 30, according to new research.
The review by researchers at Indraprastha Apollo Hospitals suggests OA should be viewed as a heterogeneous syndrome rather than a single disease. The condition is driven by a combination of biological, biomechanical, metabolic, genetic, and molecular factors, but in youth obesity and poor lifestyle is surging the cases.
“Osteoarthritis is no longer confined to the elderly — we are now seeing patients as young as 30, often driven by obesity and sedentary lifestyles. This research makes clear that osteoarthritis is not a single disease but a spectrum of conditions,” said Dr. (Prof.) Raju Vaishya, Senior Consultant Orthopaedic and Joint Replacement Surgeon, Indraprastha Apollo Hospitals.
Noting that a one-size-fits-all approach may not help, the expert stressed the need for personalized treatment that recognizes the specific phenotype in each patient.
Also read: Can Running Marathons Or Ultramarathons Raise Colon Cancer Risk? Study Sparks Concern
The review, published in International Orthopaedics, identifies six disease subtypes, including inflammatory, metabolic, and pain-sensitization variants. Researchers recommend MRI-based tools and biomarker panels to guide treatment decisions.
Emerging technologies such as AI-assisted MRI scoring and PET-MRI with 18F-NaF may also enable earlier detection and better patient classification, although wider clinical adoption will require standardized protocols and large-scale validation studies.
More than 500 million people worldwide live with osteoarthritis, accounting for 7.6 per cent of the global population. According to Global Burden of Disease estimates, prevalence has increased by 132 per cent over the past 30 years and is projected to rise by another 60 per cent by 2050.
Women, people with obesity, and those with previous joint injuries are disproportionately affected.
Read More: Hepatologist Recommends 9 Most Effective Exercises For Better Liver Health
Osteoarthritis occurs when the cartilage that cushions the ends of bones gradually wears down, causing joints to become stiff, painful, and less mobile.
The disease commonly affects the knees, hips, and small joints of the hands, although it can occur in almost any joint.
Common symptoms include:
Experts say maintaining a healthy weight, staying physically active, avoiding prolonged sedentary behaviour, and preventing joint injuries can help lower the risk of osteoarthritis.
One of the biggest challenges in osteoarthritis treatment is the “care gap.” Many patients are too young or not yet severe enough for surgery but may spend years relying on medications that relieve symptoms without addressing the underlying mechanics of joint stress.
Research suggest gait retraining — adjusting the way a person walks — could help bridge this gap. Unlike medication or surgery, gait retraining is non-invasive and may offer a sustainable long-term solution.
Currently, gait retraining often requires specialized tools such as motion-capture systems and pressure-sensitive treadmills. However, newer approaches, including smartphone-based video analysis and sensor-equipped “smart shoes,” are being developed to make the technique more accessible.
Experts caution against making major changes to walking patterns without professional guidance, as improper adjustments may place additional strain on other parts of the body.
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