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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
Credit: AI
People think of menopause as just hot flashes and irregular periods, but menopause is more than that.
Perimenopause and menopause can bring a host of emotional and cognitive shifts for many women, including mood swings, anxiety, easily irritated, trouble sleeping, or having what some refer to as “brain fog.”
Perimenopause is the period leading up to menopause that can last anywhere from two to eight years. This is when hormonal changes take place, especially a drop in estrogen.
These hormonal changes also impact neurotransmitters like serotonin and dopamine that are essential for mood, memory, sleep and emotional wellness.
Consequently, a woman can suffer from forgetfulness, lack of concentration, mental tiredness, low energy levels, dry skin, loss of libido and less productivity.
Also read: Shamita Shetty’s Endometriosis Diagnosis Sparks Concerns About Risks Of Delayed Detection
Brain fog can be a frustrating and overwhelming experience during menopause, particularly if a woman is juggling her career, family, ageing parents and personal obligations.
Many women suffer from anxiety symptoms, even if they have no mental health background. Hormonal changes, poor sleep and stress can exacerbate these symptoms.
But not all symptoms are due to the menopause or "normal ageing". Thyroid disorders, vitamin deficiencies, depression and other medical problems can have similar symptoms.
Therefore, if symptoms start to impact life, work, relationships or emotional wellbeing, it is important to seek medical advice and have a proper health check-up.
Management is often comprehensive, and may involve lifestyle modifications. Regular exercise, balanced nutrition, stress management and healthy sleep patterns.
In a few instances, you may additionally be suggested to take Menopausal Hormone Therapy (MHT). As more research is done and preparations of lower doses and greater safety, earlier misconceptions about hormone therapy are gradually decreasing.
Medically, women can make a difference in their quality of lives and manage menopause with greater physical, mental and emotional wellness with early recognition and timely intervention.
By Dr. Nidhi Sharma Chauhan, Gynaecologist, Saifee Hospital
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Everyone knows that using sunscreen is one of the most important steps for protecting the skin from harmful sun rays, but dermatologists explain that it isn't the only thing you should do to keep your skin healthy. Other daily routines are also important for minimizing sun damage and maintaining healthy skin over time.
Skin is a protective barrier for the body but constant exposure to the sun, pollution, heat and unhealthy lifestyle habits can make this barrier vulnerable.
Once the skin barrier is damaged, the skin is more susceptible to tanning, pigmentation, dryness, sun ageing and other sun damage.
Using a moisturiser every day is a very simple, yet effective habit. A good moisturiser is one that doesn't contain any scents and will support the barrier function of the skin, thereby preventing unwanted water loss from the skin.
Wet and plump skin is resistant to the environment and sun's rays.
Also read: Add These 8 Foods To Your Diet For Batter Hair, Skin And Nails
Antioxidants are also a best practice for dermatologists. Antioxidants prevent the damage to skin cells by free radicals created by UV exposure, pollution etc.
This protection can help minimize issues like hyperpigmentation, uneven skin tone and premature ageing. Consuming foods that contain antioxidants (such as fruits, vegetables and nuts) can help keep skin healthy on the inside.
Next, hydration is crucial. It's important to keep drinking enough water all day long to keep the skin supple and to allow the skin to repair itself. Moisture also contributes to skin's healing from environmental stress.
Sun protection is also of great importance. Wearing hats or caps, using umbrellas, and wearing clothing that protects against the sun's rays can minimize direct exposure to the sun.
All these are simple actions that serve as a physical barrier and prevent sunburn and long term damage to the skin, particularly between 10 a.m. and 4 p.m. These simple steps provide a physical barrier and reduce the risk of sunburn and chronic skin damage, particularly in the peak hours of 10 a.m. to 4 p.m.
Also read: Dermatologist Reveals What To Add And Remove From Skincare Routine For Season Change
Another focus has been on the connection between gut health and healthy skin, as experts recognize how crucial the role of the gut is in maintaining healthy skin.
Probiotics can potentially improve the gut-skin axis and aid in the healing process and alleviate inflammation in the body. The better the gut environment, the better the skin will be able to recover and the less the exposure to the sun will age the skin.
Some people can use collagen supplements as an added benefit. Collagen is involved in supporting the dermis, the skin's structural component. Keeping collagen high can help promote skin repair and healing mechanisms.
Doctors say while sunscreen is important, long-term skin protection can be achieved through a variety of healthy habits, proper nutrition, hydration and physical sun protection measures, which must be followed daily.
Dr. Pravin Banodkar Senior Consultant Dermatologist Saifee Hospital
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We tend to think of our eyes as easy – they just "see", and we go about our day. But the fact is, your eyes are adapting a lot, focusing and straining all the time, far more than you realize. Many of these moments are utterly unremarkable, but they build up gradually into a tiredness, a dryness and a long-term strain.
We see many people who are shocked to find out how hard their eyes had been working long before any symptoms appeared. Here are six common situations that deserve a whole lot more attention – and care – from your eyes.
Having a quick glance at notifications before even leaving bed requires your eyes to adjust to a small, bright screen in the dark. This quick change puts a load on the eye muscles and can make them tire before your day has really started.
Working, studying, and hopping from meeting to meeting: extended hours in front of the screen drastically lower your usual blink rate. Less blinking equals less lubrication, which is why so many people are dry, irritated and have blurry vision by the afternoon.
Night driving is one of the most challenging visual jobs humans undertake, given low light, incoming headlights and the need to constantly change focus between the road, mirrors and dashboard. Your eyes are working tirelessly to shift between bright and dim situations in fractions of a second.
Night driving is one of the most challenging visual jobs humans undertake, given low light, incoming headlights and the need to constantly change focus between the road, mirrors and dashboard. Your eyes are working tirelessly to shift between bright and dim situations in fractions of a second.
Also read: El Salvador Becomes First Country In Central America To Eliminate Trachoma: WHO
Poorly lit restaurant menus, pharmaceutical labels, or the small text on a contract all demand that you focus hard at close range, frequently in less-than-ideal illumination. As we get older, this type of near-focus strain is very common since our natural ability to focus declines.
Glancing from your laptop to your phone to a television and back again, it makes your eyes refocus at multiple distances. It is easier, but this continual flipping is more tiring than looking at one screen for the same period of time.
Your eyes work hard to adjust while you move from a dim room into harsh daylight — or vice versa. Over time, repeated exposure to glare without the correct protection (such as sunglasses) can add unneeded strain.
None of these moments feel dramatic on their own, but together, they represent a significant daily workload for your eyes. The good news is that habits such as the 20-20-20 rule, correct lighting, regular blinking and eye check-ups can go a long way in reducing this concealed tension. We believe that awareness is the beginning of healthy eyesight.
If you are suffering frequent eye strain, dryness or fuzzy vision, it may be time to schedule a full eye exam. Your eyes work harder than you realize – let’s give them the attention they deserve.
Dr Mandeep Singh Basu, Ayurvedic Eyecare Expert, Dr Basu Eye Care Centre
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