How Old Are Your Organs? New Study Links Organ Aging to Disease Risk

Updated Mar 19, 2025 | 05:00 PM IST

SummaryThe blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
How old are your organs?

Credits: Canva

A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

  • Heart
  • Blood vessels
  • Liver
  • Immune system
  • Pancreas
  • Kidneys
  • Lungs
  • Intestines
  • Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

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The 10-Minute Silence Test: What Your Brain Reveals When You Stop Filling Every Quiet Moment With Your Phone

Updated Oct 9, 2026 | 01:11 PM IST

SummaryOur phones have become so closely woven into everyday life that we often reach for them before we even realize we are bored.The problem isn't the phone. It's the constant need for stimulation.
The 10-Minute Silence Test: What Your Brain Reveals When You Stop Filling Every Quiet Moment With Your Phone

Credit: iStock

When was the last time you stood in a queue without looking at your phone? Or had a cup of tea without scrolling through messages? Or sat in a car, waiting for someone, without opening Instagram simply because there was nothing else to do?

Try it today. Put your phone away for 10 minutes and do absolutely nothing with it. It sounds easy. For many of us, it isn't. The first thing you may notice is not peace, but restlessness. You may wonder if someone has messaged you. You may feel like checking the news, looking at the time or opening an app without even knowing why.

As a neurologist, I find this interesting because it tells us something about how we have trained our attention. Our phones have become so closely woven into everyday life that we often reach for them before we even realize we are bored.

The problem isn't the phone. It's the constant need for stimulation. There is nothing inherently wrong with using a smartphone. We use it to work, communicate, navigate, learn and stay connected.

The problem begins when every small gap in our day has to be filled.

Waiting for the lift? Check the phone.

Waiting for your coffee? Scroll.

Watching television? Check messages.

Feeling slightly bored? Open an app.

Our brains are naturally drawn towards novelty. A notification, a new message or a fresh video gives our attention something new to respond to. When this happens repeatedly, checking the phone can become almost automatic.

That is why I sometimes ask patients not only how much time they spend on their phones, but how often they feel the need to check them. Those are two very different questions.

What Happens When The Screen Goes Away?

The first few minutes may feel surprisingly busy inside your head. An unfinished conversation may come to mind. So might tomorrow's meeting, a pending task or something that has been worrying you. You may also find yourself simply daydreaming.

We often assume that a quiet mind should mean an empty mind. It doesn't. When there is no constant stream of information coming from outside, the mind naturally moves towards memories, plans, emotions and thoughts that have been sitting in the background.

That isn't necessarily overthinking. It is part of normal mental activity. Sometimes we are so quick to distract ourselves that we don't give ourselves the opportunity to notice what we are actually thinking or feeling.

What Should Concern Us Is Fragmented Attention

There is another part of this conversation that gets overlooked. We often talk about screen time, but the way we use our screens matters too. Imagine someone working on an important task but checking WhatsApp every few minutes, responding to an email, looking at a notification and then returning to the original task. Even if the total phone usage doesn't look alarming, their attention has been repeatedly pulled away.

Over time, this can make uninterrupted concentration feel uncomfortable.

So instead of asking only, “How many hours am I on my phone?”, perhaps we should occasionally ask, “How often am I allowing my attention to be interrupted?”

Try The 10-minute Test

You don't need to give up your phone or spend an hour meditating. Start small.

Have your morning tea without a screen. Sit on the balcony. Take a short walk without headphones. Wait for five or 10 minutes without automatically reaching into your pocket.

Don't try to stop your thoughts. Just notice them. You may discover that you are more restless than you expected. Or perhaps you will find that your mind settles after a few minutes.

Either way, that is useful information. Mental wellbeing isn't only about learning how to manage stress when it becomes overwhelming. It is also about creating small pockets of time in which the brain isn't constantly being asked to consume, respond and move on.

In a world that has made every spare minute scrollable, being comfortable with a little silence may be a surprisingly valuable habit for the brain.

(Dr Neha Pandita, Senior Consultant Neurologist and Unit Head, Clinical Lead - Parkinson's disease & Movement Disorders, Fortis Hospital, Noida)

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Heart Failure Doesn’t End At Hospital Discharge: Why The First Year Matters

Updated Oct 9, 2026 | 07:00 AM IST

SummaryThe months following discharge from the hospital are a crucial period, when continued treatment, follow-up and attention to changes in symptoms can make a meaningful difference.
Heart Failure Does Not End At Discharge: Why The First Year Matters

Credit: iStock

For someone who has been hospitalized with heart failure, going home from the hospital can feel like a turning point. The breathlessness may have eased, the swelling may have reduced, and normalcy returns slowly. But feeling better does not mean that the condition has been cured. However, heart failure is a chronic and progressive condition in which the heart is unable to pump blood effectively enough to meet the body's needs.

The course of heart failure can include periods when patients feel stable and periods when their condition worsens. A worsening episode may require hospitalization or additional treatment, but even after the immediate episode has been stabilized and the patient is discharged, the underlying heart failure remains. The months following discharge from the hospital are a crucial period, when continued treatment, follow-up and attention to changes in symptoms can make a meaningful difference.

Why The Risk Remains After Discharge

People who have recently experienced a heart failure episode are at higher risk of their condition worsening again. The period after discharge should therefore not be viewed simply as a return to normal life, but as a phase when continued monitoring, follow-up and treatment remain important.

The risk is reflected in the outcomes after discharge. Within one year, studies have reported a heart failure readmission rate of nearly 30%, while all-cause mortality was 37%. This highlights why the months following hospitalization require particular attention, even when symptoms have improved.

A heart failure hospitalisation is also an important marker of future outcomes. In patients with recurrent multiple heart failure hospitalizations, the risk of cardiovascular death and all-cause mortality is six times higher in patients with four or more heart failure hospitalisations compared with patients with no heart failure hospitalizations.

This makes preventing another worsening episode an important part of long-term heart failure management.

For example, a patient may return home after treatment feeling less breathless and able to resume a daily routine. If, after some time, the same person begins to struggle with a regular walk, develops increasing ankle swelling, or takes longer to recover from everyday activity, these changes should not be ignored. They may indicate that heart failure is worsening again and should prompt a timely conversation with the doctor.

Continued Care Can Help Reduce Future Risk

Recognizing this period of increased vulnerability is not intended to create fear, but to encourage timely care. Patients should take their medicines exactly as prescribed and keep their follow-up appointments. Patients and their families should also be aware of the warning signs that indicate the condition may be worsening. This includes symptoms such as breathlessness; swelling of the legs or ankles; reduced ability to exercise; lack of appetite; nausea; increased heart rate; weight gain from fluid build-up; dizziness; or lightheadedness.

If familiar symptoms return, become more frequent or severe, or begin to affect everyday activities, the doctor should be consulted promptly. Regular follow-ups also provide an opportunity to assess whether the condition remains stable and treatment continues to meet the patient's needs.

Even when patients are stable with current treatment, the risk of hospitalization or serious cardiovascular outcomes can remain. Timely and appropriate treatment, including newer therapeutic approaches where suitable, can help reduce this risk.

Hospitalization following heart failure should not be seen as an episode to recover from, but as a reminder of the need for continued care in the months to follow. Patients and families who understand the warning signs, stay consistent with treatment and follow-up, and consult with the doctor regularly are better placed to manage the risk.

By Dr KV Srikanth, Consultant Interventional Cardiologist, KIMS Hospital, Electronic City, Bengaluru

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Teen Reproductive Health Problems May Be Linked To GI, Mental Health & Chronic Pain In Adulthood: Lancet

Updated Oct 9, 2026 | 12:00 AM IST

SummaryA recent study published in The Lancet Regional Health – Americas found that reproductive problems during teenage years could cause pelvic pain and other health conditions decades later.
Pelvic Pain In Adulthood May Be Linked To Teen Reproductive Health Problems: Lancet

Credit: AI

Chronic pelvic pain in adulthood may have warning signs that appear much earlier in life. A new study suggested that reproductive and gynecological health problems during adolescence could identify people at higher risk years before chronic pain develops.

The study, carried by The Lancet Regional Health – Americas, analysed health data of nearly half a million people in Ontario, Canada, following them from adolescence into adulthood.

The researchers found that after 10 years into adulthood, chronic pelvic pain affected 28% of people who had sought healthcare for gynecological or reproductive health problems during their teenage years, compared to about 15% among those without such health issues during adolescence.

In a nutshell, the rate of chronic pelvic pain was 41% higher among people who had earlier gynecological or clinical visits due to reproductive issues.

Findings Just Not Restricted To Pelvic Pain

Also read: High BP in Pregnancy Linked to 42,000 Maternal Deaths, 500,000+ Stillbirths, Newborn Deaths: WHO

The researchers used population-based health data held by ICES and followed people from adolescence into adulthood. The analysis also considered other health problems and healthcare use during adolescence.

The findings also indicated that teenagers who had sought care for gynecological or reproductive problems were also more likely to have gastrointestinal problems, mental health conditions and chronic pain in other parts of the body.

“We asked a simple question: Were there signs, years earlier, that someone was on a path toward chronic pelvic pain? This study shows that indeed, the gap between those affected by CPP was already visible early in adulthood and grew over time,” said lead author Shay Freger, a PhD candidate in McMaster University's Department of Obstetrics and Gynecology.

What Is Chronic Pelvic Pain?

Also read: Childhood Fitness Linked To Lower Risk Of Depression In Adulthood: 30-Year Study

Chronic pelvic pain refers to persistent pain in the lower abdomen or pelvic region that can continue for months or years.

It can affect everyday life, education, work, relationships and mental health. Researchers also identified that pelvic and menstrual symptoms during adolescence can sometimes be dismissed as a normal part of growing up, even when the pain is severe or persistent. This could discourage a person to seek medical help.

The findings suggest that these symptoms could offer doctors and healthcare experts a key opportunity to identify patterns of certain health conditions earlier in life.

“What is important about this study is that the warning signs were not limited to reproductive health alone,” said Mathew Leonardi, senior author and associate professor in McMaster’s Department of Obstetrics and Gynecology.

“It suggests that adolescent menstrual and pelvic health may be part of a broader health picture that deserves earlier attention and more integrated care.”

Not A Cause-And-Effect Relationship

The study just noticed an association, but it does not establish that adolescent gynecological or reproductive problems are the direct reasons behind chronic pelvic pain decades later in life.

Instead, the researchers say the findings indicate that healthcare providers may already be seeing patterns during adolescence that could be linked with greater vulnerability to chronic pain and other disorders in adulthood.

The researchers also said that recognising these patterns earlier could help shift pelvic pain care from treating to identifying and addressing problems before they become persistent.

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