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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
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Aarogya Setu started as a contact-tracing and tracking app during the COVID-19 pandemic. But it underwent a significant transformation since its initial launch. Now, years after its launch, the Centre has launched Aarogya Setu 2.0.
Instead of focusing only on infectious diseases, Aarogya Setu 2.0 now acts as a comprehensive healthcare app that provides a range of healthcare services. Its features are designed to change the way you obtain medical services in hospitals and other healthcare facilities.
It can help users store, retrieve, and manage their medical records, access various services, and simplify everyday healthcare tasks. Apart from data and records storage, the app can help users locate the nearest hospitals, manage their prescriptions, and track their insurance coverage seamlessly. The revamped platform is designed to address common challenges patients face while navigating India's healthcare system.
Here's a closer look:
One of the most useful features Aarogya Setu 2.0 provides is access to the locations of the closest hospitals and healthcare facilities. In times of emergencies, this feature could prove to be lifesaving as it could save valuable time when immediate medical attention is needed.
The app has also enabled searching for PM-JAY empanelled hospitals. This feature is integrated with Pradhan Mantri Jan Arogya Yojana, allowing users to search for empanelled hospitals offering cashless treatment. Users can easily find authorized hospitals and access free or subsidized care.
Read more: Ebola Outbreak Spreads To Fourth Province In DR Congo As Cases Rise To 1,274
Patients often struggle to recall their medical history, including details like previous illnesses, surgeries, allergies, medications, or vaccinations during a consultation. It often hinders the diagnostic process as the doctor does not have a comprehensive picture of the patient’s health.
The platform provides users with easy access to their health records, making it simpler to share relevant information with their healthcare providers whenever needed.
Read more: Leptospirosis In Monsoon: Expert Explains Why Early Detection & Prevention Is A Must
Patients are often compelled to undergo the same diagnostic tests and scans simply because their previous reports get misplaced. This not only increases healthcare costs but also causes inconvenience. Easy access to past laboratory reports can help patients avoid unnecessary repeat tests.
Medical insurance paperwork often involves submitting hospital documents, prescriptions, diagnostic reports, and discharge summaries. Since many of these records are scattered across different hospitals or stored as paper documents, patients may spend considerable time collecting them.
With digital health records stored in one place, users may find it easier to retrieve documents required for insurance claims or cashless hospitalization, potentially reducing paperwork and delays.
Aarogya Setu 2.0 allows users to securely store and access digital health records through integration with India's digital health ecosystem. Having previous prescriptions and reports readily available can help both patients and healthcare providers make informed decisions.
This is particularly useful for individuals who relocate frequently and suffer from chronic conditions such as diabetes, hypertension, asthma, thyroid disorders, or kidney disease that need long-term monitoring.
Changing cities usually means changing doctors and hospitals. In the absence of a complete medical history, one is more likely to incur additional healthcare costs of retaking the tests.
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As heatwaves have become more frequent and intense across the globe, health experts are increasingly warning that soaring temperatures affect far more than physical health. While dehydration, heat exhaustion, and heatstroke are common physiological effects of heatwaves, extreme heat can also take a significant toll on mental wellbeing.
HealthandMe spoke to Dr. Samant Darshi, Consultant - Psychiatrist & Neuromodulation Expert, Psymate Healthcare, Noida, about the psychological impact of extreme heat.
In hot weather, the human body constantly works to maintain a stable internal temperature. During periods of extreme heat, this process becomes increasingly challenging, placing considerable strain on both the body and brain.
Dr Darshi explains, “The high temperatures during heat waves can have a strong influence on not only physical but also the psychological state of people. The hot weather causes irritation, nervousness, stress, and frustration. Sleep disturbance associated with the hot weather only complicates the process of keeping a good mood.”
Living in higher temperatures is slowly becoming the new norm in several countries. With climate change driving longer and more intense heat events, understanding the psychological impact of extreme heat has become more important than ever.
Additionally, research has shown that prolonged exposure to heat can worsen stress, anxiety, irritability, and even increase the risk of severe mental health crises. Moreover, people's ability to think logically is affected by heat; memory, attention, and overall productivity decrease in extreme temperatures.
Dr Darshi says, “People with some pre-existing mental health conditions (depression, anxiety disorders, schizophrenia, etc.) can suffer from worsening their symptoms during prolonged heatwaves. The side effects of some medications that are used for the treatment of mental illnesses include the disturbance of the processes of thermoregulation in the organism.”
High temperatures can also disrupt sleep, hamper hormone levels, and affect neurotransmitters like serotonin and dopamine, which play a key role in regulating mood. Sleep deprivation, a common consequence of hot nights, can further intensify emotional distress, making people feel more anxious, irritable, or overwhelmed.
As temperatures soar, people generally avoid stepping out, becoming increasingly secluded. Lack of social interactions triggers the brain’s primal ‘survival threat’ alarm, which can lead to excessive stress, poor emotional regulation, and increased risk of anxiety and depression.
It especially affects older people and other vulnerable groups. Social isolation can cause psychological problems in terms of loneliness and depression. In extreme cases, prolonged exposure to heat causes aggression, self-harm, and other mental health crises.
While one has little to no control over the weather, certain measures can help reduce the mental strain caused by extreme heat:
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Leptospirosis gained attention after its cases surged in Kerala recently. The infection has also been reported in Maharashtra, Gujarat, Tamil Nadu, and Karnataka. The bacterial infection typically spreads via contact with water or soil that has been contaminated by the urine of animals infected with leptospirosis, especially during floods.
As monsoons are right at our doors, know why it is important to detect and nab dangerous infections like leptospirosis early.
Leptospirosis is a potentially serious bacterial infection sometimes called the "rat fever" because it can cause symptoms similar to the typical symptoms of common viral infections, which may not be noticeable in the early stages. It is caused by the bacteria of the genus Leptospira that are excreted in the urine of infected animals, including rats, cattle, dogs, and pigs.
In the monsoon season, there is a risk of waterlogging and contaminated animal urine mixing with floodwater and soil. Infestation occurs through direct contact with contaminated water or mud on cuts or abrasions or on the mucous membranes of the mouth, nose, and eyes. Those involved in outdoor work, sanitation, farming, construction, or who are walking in flooded streets are especially at risk.
Health and Me spoke to Dr. Sundar Krishnan, Senior Consultant - Internal Medicine, KIMS Hospital, Thane, about how to tackle leptospirosis this monsoon.
Dr. Krishnan says, “In the early stages, it may have flu-like symptoms, and that makes early recognition challenging. Symptoms are sudden onset of high fever, chills, very severe headache, muscle pain especially in the calves and lower back, fatigue, nausea, vomiting, and red eyes.”
The expert also said that occasionally, the patient may also have abdominal pain or diarrhea. He also says it can escalate quickly to jaundice, kidney failure, difficulty breathing, meningitis, internal bleeding, or multi-organ failure and can require immediate medical care.
Dr. Krishnan recommends several prevention tips to tackle leptospirosis in monsoon:
If leptospirosis is diagnosed early and treated with antibiotics, recovery is much quicker, avoiding life-threatening complications. But if detection and treatment are delayed, the kidneys, liver, lungs, and even the brain may be affected.
The expert advises that people who are ill after being exposed to flood water and are facing fever or flu-like symptoms for more than two days should also seek medical help as soon as possible, informing their doctor about their flood water exposure.
Even though the risk of leptospirosis is high during the monsoon, the best way to steer clear of this infection is to educate the masses about its symptoms and prevention. Early clinical intervention can help de-escalate the situation promptly.
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