How Old Are Your Organs? New Study Links Organ Aging to Disease Risk

Updated Mar 19, 2025 | 05:00 PM IST

SummaryThe blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
How old are your organs?

Credits: Canva

A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

  • Heart
  • Blood vessels
  • Liver
  • Immune system
  • Pancreas
  • Kidneys
  • Lungs
  • Intestines
  • Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

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Oncologist Answers: Can Heating Food In Black Plastic Bowls Give You Cancer?

Updated Apr 26, 2026 | 01:00 PM IST

SummaryBlack plastic containers have 'carbon black,' which, upon heating, releases toxic, cancer-causing chemicals.
black containers

Take-out food often comes in black plastic containers, but these are far from safe for your health. (Photo credit: iStock)

Plastic containers have been discouraged for a long time now, especially for heating food or storing hot food. Studies have associated this habit with a heightened risk of cancer, but now an expert has specifically spoken about black plastic containers and what makes them worse for you. According to Dr Rakesh Kumar Sharma, Senior Consultant Medical Oncologist at M | O | C Cancer Care & Research Centre, Gurugram, cooking or heating food in black containers could be very harmful to your body. Read on to find out how.

Dr Sharma, in an interview with Health and Me, said that cooking food in black plastic receptacles could lead to greater amounts of certain chemicals making their way into your body; however, there currently exists no scientific evidence confirming that this daily activity increases your risk of cancer.

Why is black plastic worse than others?

Dr Sharma explained that black takeaway containers usually consist of recycled plastics, such as e-waste, and can contain flame retardants, BPA, phthalates, etc. When heated in contact with food, especially if the food is hot, fatty, or acidic, more chemicals could potentially make their way into the food from the container. In this way, it may, over time, heighten your risk of developing a malignant tumour.

Black containers are coloured using carbon black, which is included in Group 2B of possible human carcinogens according to IARC, as shown in both animal and limited human research. Moreover, recycled black plastics could contain polycyclic aromatic hydrocarbons and decaBDE, which have shown carcinogenic effects in experiments. This makes black plastic containers worse than other coloured counterparts. Yet, heating food in a plastic container of any colour is not deemed safe.

Do studies verify the side effects of heating food in plastic containers?

Experimental studies conducted in laboratories on microwaveable plastic receptacles reveal the migration of tens of chemicals and millions of microplastics per litre of the food simulant. However, a recent study in 2024 reported that containers labelled as microwave-safe in Korea adhered to contemporary safety standards for these levels, and total exposure fell within safe limits.

Leading cancer associations have confirmed that the usage of plastic packaging, even in microwave applications, has not been linked with increased cancer risks in humans, although there is ongoing research in areas such as black plastics. However, precautionary measures are suggested by experts as a better strategy due to the difficulties of directly studying long-term, low-level exposure to chemical compounds.

How to reduce cancer risk?

When it comes to reducing cancer risk, most doctors recommend quitting smoking and limiting alcohol intake. However, Dr Sharma listed some basic kitchen and eating habits that may come to your rescue:

  1. Avoid cooking food in black plastic packaging, particularly if the food is oily or acidic.
  2. Move hot food into glass, ceramic, or stainless steel containers for reheating.
  3. Only use microwave-safe containers and discard any broken plastic containers.

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Decoding Depression In Men: The Emotion Behind The Silence

Updated Apr 26, 2026 | 05:00 PM IST

SummaryOne of the key barriers in identifying depression in men is the way emotional awareness is shaped from an early age. Many men are conditioned to respond to discomfort through action rather than reflection.
Decoding Depression in Men: The Emotion Behind The Silence

Credit: iStock

Depression in men often does not look like the depression we all know about. It is never visible sadness or a verbal expression of emotional pain. The emotional dish is missing from the life menu of a man.

It hides behind productivity, irritability, exhaustion, or strong discipline. This masking makes it the most underdiagnosed mental health concern, frequently misread as stress, burnout, or simply personality traits.

One of the key barriers in identifying depression in men is the way emotional awareness is shaped from an early age. Many men are conditioned to respond to discomfort through action rather than reflection.

The moment something feels overwhelming, the instinct is not to sit with the feeling but to fix it, outperform it, or suppress it through movement—work, exercise, or distraction.

While this can provide short-term relief, it often delays emotional processing and deepens internal distress over time.

Clinically, this disconnect is often linked to alexithymia—a difficulty in identifying and articulating emotions.

The emotional signal is present, but it does not translate easily into words. Instead of “I am sad” or “I feel afraid,” the experience gets reduced to “I am tired” or “I am stressed.”

This limited emotional vocabulary can significantly affect help-seeking behavior like therapy and counselling, as the man does not recognize the depth or nature of what they are experiencing.

Depression In Men: Poor Physical Health

From a health perspective, unresolved emotional stress is not limited to the mind. It reflects in the body.

Chronic fatigue, sleep disturbances, headaches, digestive issues, and muscle tension are some of the symptoms seen.

Men who are very aware tend to see general physicians and not go to mental health professionals, treating physical symptoms while the psychological root remains unattended to.

Another way is externalized emotion. Irritability, anger outbursts, or risk-taking behaviour are often socially accepted expressions of underlying emotional pain.

A man working excessively, exercising compulsively, or withdrawing socially may, in fact, be coping with grief, loneliness, or anxiety, which are socially normal.

Our culture around masculinity complicates diagnosis even more. Strength is seen with emotional control, and vulnerability is seen as weakness.

Most men do not seek psychological support until symptoms become severe or functionally impairing. They struggle to express their internal state, reinforcing the cycle of silence.

Depression In Men: Physiological Indicators

Understanding depression in men requires shifting the lens from visible sadness to behavioral and physiological indicators.

It requires mental health practitioners and caregivers to look beyond surface functionality and recognise that high performance can coexist with deep emotional distress.

Early intervention is very important. Creating environments where emotional language is normalised without judgement or immediate problem-solving can significantly improve the situation. When men are given consistent permission to articulate internal states without fear of stigma, the gap between emotional experience and expression begins to close.

“Expressing your feelings should lead to a deeper connection, not conflict. It should invite empathy, not ego-driven reactions. It should bring relief, not retaliation or emotional punishment. If sharing your pain feels unsafe or punished, you are not in a healthy relationship—you are in an emotional environment where fear has replaced trust.”

Depression in men is not a lack of feeling, but a lack of translation. True healing begins when that translation is finally allowed to happen.

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No Pain, No Problem: Oncologist Debunks A Common Myth About Testicular Health

Updated Apr 26, 2026 | 09:00 AM IST

SummaryPainless lumps are a key early sign of cancer and must never be overlooked.
Testicular health

Young men must go for regular health check-ups to rule out the possibility of health problems later.

Most young men assume that if there is no pain, there is no serious problem. Unfortunately, many important testicular conditions, especially testicular cancer, often begin as a painless lump, swelling, or enlargement of one testicle. Because there is no pain, men tend to ignore it, thinking it is due to exercise, minor trauma, tight clothing, cycling, or temporary swelling. Embarrassment and reluctance to discuss genital symptoms also contribute to delay.

Dr. Chandan M. N, Consultant Urologist, Andrologist, Uro-Oncologist & Renal Transplant Surgeon, Apollo Hospitals, Sheshadripuram, Bangalore, spoke about the pain conundrum. The expert said that when it comes to testicular health, absence of pain must not be a reassuring factor.

Pain is usually seen as a warning signal, but in testicular disease, absence of pain should not reassure patients. Testicular cancer is one of the most common cancers in young men, particularly between 15 and 35 years of age, and it can progress quickly if diagnosis is delayed. However, when detected early, it is also one of the most curable cancers.

What are the common signs men may overlook in day-to-day life?

The most commonly overlooked sign is a painless lump or swelling in one testicle.

Sometimes the change is subtle; a testicle may simply feel slightly harder, heavier, larger, or firmer than before. Many men also ignore a dragging sensation, heaviness in the scrotum, or a dull ache in the groin or lower abdomen because these symptoms are mild and not severe enough to disrupt daily life.

Other signs that should not be ignored include sudden fluid collection in the scrotum, change in the shape or size of one testicle, unevenness between the two testicles, persistent discomfort, or a feeling that something is different. Some men may also notice back pain, breast tenderness, or unexplained swelling if the disease has spread. Importantly, not every testicular lump is cancer. Conditions such as hydrocele, varicocele, spermatocele, orchitis, or hernia can also present with swelling or heaviness. But the only safe approach is to get examined rather than assume it is harmless.

How to do a simple self-examination at home?

Young men should know what is normal for their own body. A simple self-examination once a month, ideally after a warm shower when the scrotal skin is relaxed, can help detect early changes.

Men should gently feel each testicle for lumps, swelling, hardness, change in size, or heaviness. Familiarity with one’s normal anatomy makes it easier to notice when something changes. Any new lump, swelling, change in shape, or persistent discomfort should be evaluated promptly by a doctor. Usually, a physical examination and scrotal ultrasound are enough to identify the cause. Early medical advice can differentiate a harmless condition from something serious and, in the case of testicular cancer, can make the difference between simple treatment and advanced disease.

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