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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
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The view generally is that the occurrence of knee issues is usually associated with age, injury or overexertion. However, there is another reason people ignore: lack of movement. If a person leads an inactive lifestyle, spending long hours sitting at a desk, working from the couch, watching TV or doing nothing physical, the eventual consequences for the knees might arise.
Knees are created for motion, and motion is essential for keeping the flexibility of a joint. Their effective functioning depends on the health of the muscles surrounding your knee. The less active various leg muscles are, including quadriceps and other counterparts, the weaker they will be. The muscles help stabilize the knee and can relieve it from some of the burdens during daily activities performed by the knees.
Remaining seated for an extended time can also lead to stiffness. When you sit for a while, you may feel uncomfortable or stiff in your knees when you finally stand up. While the occasional instance of stiffness may go away with movement, constant stiffness can impact mobility and cause people to wish to move even less.
Another issue is gaining weight. Living a sedentary lifestyle causes individuals to become heavier, and excess weight puts more stress on the knees. In time, this added pressure will lead to increased wear of the joints and the development of knee pain and other problems in the musculoskeletal system.
The positive aspect with respect to your knees is that you don’t have to put in hours at the gym to keep them safe. Small, steady efforts can easily do the trick. You can choose to walk for five minutes after being seated for a long time, stretch regularly, take stairs if you are physically able and do some simple workouts for the legs and thighs to increase strength. Low-impact sports such as swimming, cycling and walking can help you maintain muscle power and flexible joints while avoiding the stress on your knees resulting from extensive workouts.
Persistent pain in the knee, however, cannot be treated as a usual symptom of ageing. Knee swelling or prolonged stiffness, difficulties climbing stairs, instability, or pain that has an impact on routine activities should be addressed by health professionals.
Movement is necessary for knees to be strong and flexible. Therefore, if you want your knees to be strong, you need to use them consistently and perform all activities without remaining still for long.
(By Dr Sujoy Bhattacharjee, Chairman & Chief, Max Institute of Robotic Joint Replacement, Max Super Speciality Hospital, Saket)
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Blocked ears are one of the most common and irritating problems associated with air travel.
While the sensation usually resolves on its own shortly after landing, for 22-year-old Aida Burkins from California, it persisted and eventually led to a frightening diagnosis of rare head and neck cancer.
Burkins was travelling to Chicago in May 2025 when her ears became blocked. When she returned home, her ears still hadn’t popped.
She later developed unusual symptoms, including hearing loss and bleeding from her throat.
“I started bleeding into my throat, which would only come out of my nose if I was bent at the hip at about 90 degrees,” the 22-year-old told Newsweek. “My hearing got worse and worse. Then I started getting more tired and losing weight.”
When Burkins sought medical help, her condition was initially dismissed as “just altitude sickness.” After several months, her hearing had deteriorated significantly.
“Everything sounded so muffled, and I had a ringing that wouldn’t go away,” she said.
Burkins eventually saw an ear, nose, and throat (ENT) specialist, who discovered a mass and noted that her adenoids — soft tissue in the throat, just behind the nose — were inflamed.
“The doctor told me he had never seen anything quite like what I had going on. He couldn’t be sure it was cancer, but he said it was very suspicious,” she told the outlet.
In February 2026, after undergoing CT scans and two biopsies, Burkins learned that she had a widespread tumour affecting the cervical lymph nodes near the base of her skull.
She was diagnosed with nasopharyngeal carcinoma, a rare type of head and neck cancer that starts in the upper part of the throat behind the nose and near the base of the skull, according to the American Cancer Society.
“Hearing I have cancer, all I thought about was not being able to see my babies grow up or do the things they want to do in life. It was horrifying,” Burkins, who is a mother to a 1-year-old and 3-year-old.
Burkins has since undergone months of chemotherapy and radiation. She is now finishing her treatment and hopes to be cancer-free soon as her body is responding well to the treatments.
According to the Mayo Clinic, nasopharyngeal carcinoma is a cancer that starts as a growth of cells in the nasopharynx, the upper part of the throat located behind the nose.
The cancer is rare in the United States and occurs much more often in other parts of the world, particularly Southeast Asia.
Nasopharyngeal carcinoma can be difficult to detect early because the nasopharynx is not easy to examine and there may be no symptoms initially.
When symptoms do occur, they present non-classic signs which include:
Treatment for nasopharyngeal carcinoma usually involves radiation therapy, chemotherapy, or a combination of the two, depending on the cancer and the individual patient.
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Perimenopause has become a regular conversation and its been high time that people are talking about it. You can see friends discussing it, social media coverage has increased and more importantly women are discussing this with their gynaecologists.
For decades, menopause was thought to be a single event - that is the day the periods stopped, but today we understand that the transition lasts for a few years. These changes can affect the quality of a woman’s life and hence I’m glad the conversation has gained more traction.
Also read: Yoga Or Strength Training: What Can Help Manage Hot Flashes During Perimenopause?
First lets understand what perimenopause is. It literally means “around menopause” Its a transition phase where the ovaries gradually change the production of the hormones, mainly oestrogen and progesterone. It usually begins in the early 40’s but some women may experience it earlier.
One of the commonest signs of this is a change in the pattern of your menstrual cycle. Periods can be become longer or shorter, heavier or lighter. Basically the menstrual cycle becomes a bit unpredictable.
But periods aren’t the only sign. A woman may start experiencing disturbed sleep cycles. She may wake up randomly at 3am or feel exhausted despite getting 7-8 hours of sleep. Hot flushes and night sweats may also occur. Mood changes, irritability, anxiety and difficulty in concentration can also affect her quality of life.
Some women complain of being forgetful or more commonly used term "experience brain fog”. They forget names, lose train of though or struggle to multitask. There can also be a change in libido, vaginal dryness, discomfort during intercourse, headaches, join pain and alterations in skin and hair.
Besides this there could possibly a change in the body composition. A woman may notice increasing abdominal fat or find difficulty in maintaining her weight even though her lifestyle hasn’t changed.
Also read: Explained: Why Some Women Start Experiencing Joint Pain As They Approach Menopause
The good part of this increase in awareness is that women are paying more attention to their health early rather than waiting of menopause. This transition phase provides a golden opportunity to reassess exercise, nutrition, sleep and preventative healthcare.
Strength training becomes even more valuable as it helps maintain muscle and bone mass.
Adequate protein, calcium and Vitamin D intake along with a balanced diet helps long term metabolic and bone health.
During this time, its important for a woman to even assess her cardiovascular health. Blood pressure, cholesterol, blood sugar and weight don’t just become numbers on the chart anymore, they become important markers of future health during this time.
However every label shouldn’t be blamed on perimenopause. Thyroid disorders, anaemia, vitamin deficiencies, depression and few other medical conditions can produce similar symptoms.
Unusually heavy bleeding, bleeding between periods or after intercourse also warrants medical assessment rather than being dismissed as “just hormones”.
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