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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
Credits: AP
At least 55 people have lost their lives and 279 remain missing after Hong Kong’s most severe fire in more than a century swept through several high-rise towers on Wednesday afternoon, officials said. Fire crews are still trying to put out the blaze in the Tai Po area and reach those who are trapped inside. By early Thursday, authorities said they had managed to control the fire in four buildings, though teams were still working on three others more than 16 hours after the flames first appeared.
A residential complex in the Tai Po district caught fire at around 2:51pm local time on Wednesday. The flames started on the bamboo scaffolding fixed to the outside of one of the buildings. This scaffolding, made of bamboo poles used by workers during repairs, burns very easily. Once it caught fire, the flames moved quickly up the outside of the building, spread into the apartments, and then reached nearby towers.
The blocks were also covered in green construction netting from the ground to the roof because renovation work was taking place. This netting caught fire as well and helped the flames advance at a faster pace. Local reports noted that the fire grew at incredible speed. By 3:34pm, it had reached a level four alarm, and by 6:22pm, it had been raised to a level five alarm, the highest alert in Hong Kong. It is now the deadliest fire the city has seen in more than 100 years.
The blaze spread in minutes because it began on the bamboo scaffolding around the building and moved to the green netting covering the towers. Both materials burn very easily. Once they ignited, the flames climbed the outside of the tower and reached many floors above. Burning fragments then dropped to the ground and set nearby buildings on fire within minutes. Wind and the open gaps created during the renovation work likely pushed the flames even faster. While officials are still examining the exact cause, they said that the flammable scaffolding, the construction materials, and the tall buildings standing close together all played a part in letting the fire grow out of control, according to Al Jazeera.
As per The American Red Cross society, here are some essential safety tips you should follow during incase a fire emergency strucks.
Smoke Alarms:
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Sonali Bendre, actor, who is known for talking about her cancer journey, inspiring other survivors to talk about it too, has found herself at the center of a heated debate after she spoke how naturopathy and autophagy helped her in her cancer recovery.
Bendre, who was diagnosed with stage 4 metastatic endometrial cancer in 2018, wrote on X that she believes autophagy played a role in her healing journey. Her post quickly drew sharp criticism from several doctors.
Members of the medical community reminded her that her remission was the result of evidence-based cancer treatments, including chemotherapy, radiation and surgery. Many emphasized that autophagy is not a recognized medical therapy and should not be presented as one.
One post from hepatologist Dr Cyriac Abby Philips on X said, “Your cancer went into remission after chemotherapy, radiation, and surgery at an advanced cancer treatment hospital. Not because of Naturopathy. Not because of autophagy. Because you have the option and privilege to opt for the best treatments from scientific practice to help you.”
Following the criticism, Bendre clarified that she was sharing her personal experience as a survivor, not medical advice. She wrote that her journey included elements she explored with the help of her naturopath, and these practices were only part of her overall healing process. In her words, “I have never claimed to be a doctor, but I am certainly not a quack either. I am a cancer survivor, someone who has lived through the fear, pain, uncertainty, and rebuilding that the disease brings.”
Autophagy is a natural process in which the body breaks down and recycles old or damaged cell components. Cells contain various structures that help them function, and over time some of these structures wear out. Autophagy acts like a clean-up and recycling system. It allows cells to dismantle faulty parts and reuse the useful components to maintain healthy cell function. Anything that cannot be used is removed by the cell.
This process is an important quality control mechanism. If too much cellular waste builds up, it can interfere with normal cell activity. Autophagy helps keep cells efficient and healthy. The scientific understanding of autophagy grew significantly after Japanese biologist Yoshinori Ohsumi won the Nobel Prize in Medicine in 2016 for his work uncovering how it works. While autophagy is essential for survival, it is not considered a medical treatment for diseases.
Experts explain that autophagy plays a complicated role in cancer. In the early stages, it may help prevent tumor formation by clearing damaged components. However, in established cancers, the same process can allow tumor cells to survive stress and become more resistant to treatments like chemotherapy.
Disclaimer: Please consult a qualified doctor or oncologist before choosing any treatment for cancer. Health and Me does not endorse alternative therapies as substitutes for evidence-based medical care. This article is based on publicly available information. All medical conditions should be evaluated and managed under the guidance of a licensed healthcare professional.
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What if you are told that the vape you are using contains bacteria found in poop. You read that right. According to a study conducted by HAYPP along with Microbiologist Reynold Mpofu at BioLabTests, bacteria like staphylococcus and bacillus were found on vape, as well as fecal bacterium, E. coli is found on vape, which is often found in public bathroom.
More than 100 million people worldwide use e-cigarettes or vapes, and at least 1 in 6 people vape in toilet. Furthermore, vapes are rarely cleaned, and thus become germ hotspots.
The study found that vape mouthpieces are highly contaminated with bacteria. More than 1.5 million colony-forming unites or CFUs were identified on the vape mouthpiece, the maximum amount measurable by the lab, carrying as many as 2,300 times more bacteria than a public toilet, which has 50 CFUs per square inch.
“Laboratory analysis revealed that the mouthpiece is the dirtiest component of the vape. This isn’t surprising given that the human mouth, largely considered to be one of the ‘dirtiest’ parts of the body, harbors approximately 700 species of bacteria, that amounts to billions of individual bacteria,” said Mpofu.
The study was able to identify a range of bacteria, including skin microbes to gut bacteria like E.coli.
Also Read: UK Investigates Impact Of Vaping On Its Young Users
The study identified these following bacteria on the vape:
The study was also able to identify bacteria on the vape body. The lab also observed a rapid microbial growth between just 2 to 3 days of use. These colonies could be seen multiplying thousand of times over.
While many of these are found on human skin or surrounding, some are intestinal bacteria, like aforementioned, E.coli, and Enterococcus, which points towards unwashed hands, explaining the transfer on the surface.
“Much like phones, vapes are frequently handled and placed on a variety of surfaces, allowing germs, oils, and dirt from hands, pockets and various environments to latch on the device. The findings confirmed the presence of bacteria, including E. coli and Enterococcus, on the vape body, likely arising from inadequate hand hygiene or the transfer of microorganisms from bathroom environments or other contaminated surfaces,” said Mpofu.
Read: Why Is My Idea Of Break Is To Have A Smoke?
The first signs of microbes start to appear within the first day of buying a brand new vape, especially around the mouthpiece.
By day three, the vape accumulates more than 2,300 times the microbial load typically found on a toilet seat.
By the seventh day, bacteria like E.coli. and Enterococcus and other fecal indicators are detected on the mouthpiece and vape’s body. Mould and bacteria are also found on levels.
By day 14, despite no new use or cleaning, the vape remains heavily contamination. The contamination does not fade overtime.
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