How Old Are Your Organs? New Study Links Organ Aging to Disease Risk

Updated Mar 19, 2025 | 05:00 PM IST

SummaryThe blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
How old are your organs?

Credits: Canva

A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

  • Heart
  • Blood vessels
  • Liver
  • Immune system
  • Pancreas
  • Kidneys
  • Lungs
  • Intestines
  • Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

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Is Chest Pain The Only Sign Of Heart Disease?

Updated Apr 12, 2026 | 06:00 PM IST

SummaryMost people think that only chest pain and tightness are signs of heart disease. However, there are several other silent symptoms. This, and many other myths associated with heart diseases, was debunked by a cardiologist.
chest pain

Not just chest pain, but even jaw pain can be associated with heart disease. (Photo credit: iStock)

There are many myths linked to heart health that can mislead people and prevent them from seeking timely help. This article helps to debunk the myths and keep the heart healthy. It is time to prioritize heart health. Dr Rahul Gupta, Director of Interventional Cardiology and Structural Heart Program, Gleneagles Hospital, Parel, Mumbai, spoke about the common myths about heart disease and listed the facts as well.

Heart problems are commonly seen in people of all age groups. However, heart health is often surrounded by myths and misconceptions that can lead to confusion and poor lifestyle choices in people. So, heart health depends on multiple factors, including diet, activity, stress, and overall lifestyle, and not just one or two habits. Here, the expert helps to debunk the myths associated with heart health and improve the quality of life.

Dispelling myths surrounding heart health

Myth 1: Only older people are at risk of heart problems

Fact: People commonly believe that heart problems can only happen in old age. However, currently, a large number of youngsters aged 25-35 are also struggling with heart issues such as heart attacks and heart failure because of stress, unhealthy diets, and lack of exercise. So, heart problems are not limited only to older people. Anyone, irrespective of their age, can suffer from them. Hence, there is a need of the hour to go for regular heart check-ups and to initiate timely treatment for heart problems.

Myth 2: If you are fit, your heart is SAFE

Fact: So, being physically active is important, but it does not reduce the chances of heart problems. Be attentive to the family history, genetics, and other factors such as high cholesterol or even stress. So, go for cardiac screening on a yearly basis to know the status of your heart health. Discomfort in the arms, jaw, or back and light-headedness can also mean that your heart is in danger.

Myth 3: Heart disease is only seen in men

Fact: Shockingly, heart disease also causes higher morbidity and mortality rates in women. The symptoms seen in women linked to heart disease are dizziness, palpitations, and even giddiness. Hence, women should also focus on their heart health. Stay alert, stay safe!

Your heart health matters. By understanding the facts and making informed choices, it is possible for everyone to protect their heart and overall well-being.

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Beyond Medicines: How DBS Surgery Is Helping Parkinson’s Patients Reclaim Movement and Independence

Updated Apr 12, 2026 | 08:00 PM IST

SummaryDoctors have to be very careful about whom they recommend DBS to. It is usually for people who take medicines for Parkinson's. The medicines do not always work well. The doctors, surgeons, and therapists all have to work to make sure everything goes well.
Beyond Medicines: How DBS Surgery Is Helping Parkinson’s Patients Reclaim Movement and Independence

Credit: Canva/ Cleveland Clinic

Parkinson's disease is a condition that affects people with Parkinson's ability to move and do things on their own. People with Parkinson's disease will find that it gets worse over time. At first, medicines can help people with Parkinson's disease.

After a while, these medicines might not work as well as they used to for people with Parkinson's disease. Some people with Parkinson's disease might even feel bad because of the medicines they are taking for Parkinson's disease.

That is when doctors might suggest something called Deep Brain Stimulation, or DBS for short, to people with Parkinson's disease. Deep Brain Stimulation is a kind of help for people with Parkinson's disease.

What Is DBS?

DBS is a kind of surgery where doctors put wires into the brain. These wires are connected to a device that is put under the skin in the chest. This device sends messages to the brain to help it work better. The brain can get mixed up. Cause people to shake or move slowly. The messages from the device help fix that.

One of the things about DBS is that it can help people move better when medicines are not working well. People might shake less. Feel less stiff. They might even be able to take medicine, which can be good because it can reduce the side effects.

It is very important to remember that DBS is not a cure for Parkinson's disease. It does not make the disease go away. It can help people do things on their own again. Many people who have DBS say they can eat, walk, and dress themselves better. These are things that can be very hard for people with Parkinson's disease.

DBS Promising For Parkinson's Patients

Doctors have to be very careful about whom they recommend DBS to. It is usually for people who take medicines for Parkinson's disease. The medicines do not always work well. The doctors, surgeons, and therapists all have to work to make sure everything goes well.

Exciting things are happening with DBS. Soon, there might be devices that can adjust on their own to help people more. This means that people with Parkinson's disease might have more hope for feeling better.

DBS is a step forward from just taking medicines. It helps people take control of their bodies again. It helps them feel more independent and dignified. That can make a difference in their daily lives. Parkinson's disease is a hard condition to deal with, but with DBS, people might feel like they can do things again. They might feel like they have their life back. DBS is a promising treatment for people with Parkinson's disease.

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Not Diabetes or Obesity: Expert Says Chronic Stress Is The New Lifestyle Disease

Updated Apr 12, 2026 | 04:00 PM IST

SummaryDiabetes is recognised as a lifestyle disorder, but chronic stress is just as serious. According to an expert, it should be classified as a lifestyle disease for a number of reasons. Find out.
Chronic stress

Chronic stress raises cortisol levels in the body. (Photo credit: iStock)

Work, school, competition—stress appears to be inevitable these days. Across age groups, many are dealing with it in some form or the other, but unfortunately stress never stops at just headaches or fatigue. It has direct effects on an individual's health through causing disease (such as cardiovascular problems); it also has indirect effects on health by negatively influencing other health behaviors such as physical activity and sleep. It is also vital to note that stress is one of the leading health risks for people in the work environment. Healthcare professionals are advised to consider both major stressors and those that occur regularly. Further discussion about stress reduction strategies is provided.

Dr Anshuman Kaushal, Director of Robotic GI, Minimal Access & Bariatric Surgery at CK Birla Hospital, Gurugram, in an interview with Health and Me, spoke about the long-term effects of chronic stress and why it can be termed a lifestyle disorder.

Mechanisms of Chronic Stress

Exposure to certain stressors activates the HPA axis, and as a result, adrenaline and cortisol are released. While these hormones play a crucial role in survival during emergencies, they can result in serious health problems when continuously present in the body. Some of the most common consequences of stress are low immunity, insulin resistance, or inflammation. It can over time result in hypertension or heart disease.

Lifestyle as the Main Cause

With growing rates of urbanisation, competitive workplaces, financial issues, and the development of technology leading to a permanently accessible Internet, the boundaries between working time and time for rest have been blurred entirely. Moreover, an insufficient amount of sleep, poor sleeping habits, and a sedentary lifestyle cause stress as well. The young generation in India has become victims of stress-related disorders the most.

Identification of the Symptoms

One of the major challenges when identifying chronic stress cases lies in the subtlety of the condition. The list of symptoms includes constant fatigue, irritability, concentration issues, headaches, tight muscles, and insomnia. Other symptoms of the condition include gastrointestinal disorders such as acid reflux, bloating, and loss of appetite that are hardly ever associated with stress.

Long-term effects of stress

Chronic stress may appear harmless, but the truth is quite contrary. When an individual is stressed for too long without controlling it, it may result in anxiety disorders like depression. Physiological side effects of stress are:

  1. Poor immunity
  2. Inflammation
  3. Obesity
  4. Diabetes
  5. Weakened memory
  6. Mood swings

What makes chronic stress a lifestyle disease?

While most lifestyle disorders are caused by environmental factors and behavioural alterations, it can be termed a lifestyle disease. These disorders are progressive and require constant intervention in the form of medication or meditation.

Managing chronic stress

Doctors say that it takes a comprehensive strategy to reduce cortisol levels in the body and uplift mood. For instance, workouts like weight training or yoga are known to increase levels of happy hormones, thereby reducing stress. Breathing exercises and meditation, too, have a positive impact on mental health. Experts recommend combining them with nutrition, proper sleep, and socialising.

Early diagnosis matters

Chronic stress is not just a symptom of modern life but also a key health problem. Recognising it as a health issue and addressing it helps combat the long-term consequences well in time. And with continued changes in lifestyle habits and patterns, a lifestyle disease like chronic stress can also be brought under control for the better.

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