A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

• Heart
• Blood vessels
• Liver
• Immune system
• Pancreas
• Kidneys
• Lungs
• Intestines
• Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

When the heart stops functioning, time doesn’t stop with it. In cases of cardiac arrest, time serves as one of the most decisive factors between survival and irreversible loss. Within a couple of seconds, the body starts losing its oxygen supply. In a few minutes, the brain starts to suffer damage. And with each passing minute without intervention, the chances of survival reduce significantly.

This severe reality is at the centre of what Dr Ankit Desai, Paediatric Anaesthetist and Founder & Director of Children’s Anaesthesia Services, explains as “a race against biological shutdown — one where the bystander is the only lifeline”.

The silent collapse: what happens in cardiac arrest

Several people have the misconception that cardiac arrest is similar to a heart attack, but they are very different. A heart attack is a circulatory issue where the heart might still be beating. However, in cases of cardiac arrest, there is an electrical failure, and the heart suddenly stops pumping blood effectively.

Whenever this occurs, blood flow to the brain and other vital organs ceases immediately. The oxygen reserves in the brain are extremely limited and typically last for about 4 to 6 minutes before any permanent injury occurs.

This is where the concept of time sensitivity becomes more important. For every passing minute without CPR or defibrillation, the chances of survival drop by approximately 7–10%. By the time 10 minutes have elapsed without intervention, survival is extremely unlikely in most cases.

“The tragedy is not just the cardiac arrest itself,” explains Dr Desai, “but the silence that follows — when no one knows what to do or hesitates too long to act.”

The brain’s narrow window of survival

The brain is the first organ to be affected during cardiac arrest. Neurons are highly sensitive to oxygen deprivation. Brain cells start to malfunction within 3 minutes. By 5 minutes, the damage starts becoming increasingly severe. Beyond 10 minutes, the chances of meaningful recovery drastically reduce. This is why immediate CPR is not just a supportive measure but a bridge that keeps oxygen flowing artificially until a normal rhythm can be restored.

Chest compressions manually pump blood to the brain and heart, delaying cell death.

Why bystander action matters more than ambulance time

Emergency medical services, even in well-equipped systems, often take several minutes to reach a patient. In urban areas, response times may be shorter, but they are rarely instantaneous. In cardiac arrest, those minutes matter more than any hospital intervention.

Dr Desai emphasises that “the first responder is almost always not a doctor — it is a family member, a colleague, or a nearby stranger”.

This makes bystander CPR the most critical determinant of survival. Studies consistently show that when CPR is initiated immediately, survival rates can double or even triple compared to cases where no bystander action is taken.

Yet fear, hesitation, and lack of training remain major barriers. Many people worry about performing CPR incorrectly, causing harm, or being held legally responsible. In reality, doing nothing is far more dangerous than taking imperfect action.

The Chain of Survival: breaking down the timeline

Medical professionals often refer to this situation as the “Chain of Survival”, which includes early detection of cardiac arrest, immediate CPR, rapid defibrillation (AED use), advanced medical care, and post-resuscitation support. Every link in this chain is highly time-sensitive. Any delay in one step weakens the entire outcome. The strongest determinant, however, remains the second step — early CPR.

Automated External Defibrillators (AEDs), if available, can help restore a normal heart rhythm if used quickly. But again, their effectiveness decreases sharply with delay. The combination of CPR and early defibrillation within the first few minutes offers the best chance of survival.

Why awareness changes everything

The key difference between life and death is less about complexity and more about readiness.

Awareness training helps transform bystanders into responders. A person who knows how to identify cardiac arrest — unresponsiveness, absence of breathing, sudden collapse — is far more likely to act immediately rather than wait.

Dr Desai highlights a critical cultural gap: “We often associate medical emergencies with hospitals. But cardiac arrest begins in living rooms, offices, gyms, and streets. The response must begin there, too.”

Basic CPR training takes less than an hour to learn, but can influence outcomes for decades. Schools, workplaces, and community programmes play a vital role in normalising this skill.

Overcoming hesitation: the psychological barrier

One aspect of cardiac arrest that often gets overlooked is human hesitation. Bystanders often freeze due to shock and uncertainty. Some assume that someone else will step in. Others underestimate the severity of the situation.

Public awareness campaigns help highlight the simplicity of CPR, which helps overcome this barrier. Hands-only CPR focuses on continuous chest compressions without mouth-to-mouth breathing, making intervention much easier and more accessible. The message is simple: push hard, push fast, and don’t stop until help arrives.

A shift from reaction to preparedness

Cardiac arrest survival is not just a medical issue, but also one of public preparedness. The Chain of Survival starts long before the emergency happens. It starts with education, confidence, and awareness.

Dr Desai states that “if more people understood how little time they truly have, more lives would be saved not by hospitals, but by ordinary people doing extraordinary things in the first five minutes”.

Conclusion: time is the real patient

In cardiac arrest, the patient is not just the person who collapses — it is time itself. Every second lost reduces the chance of recovery. Every trained bystander becomes a potential lifesaver. The science is clear, the timeline is unforgiving, and the solution is remarkably simple: act immediately, compress the chest, and keep blood flowing until professional help arrives.

For years, PCOS was often diagnosed through the most visible disruptions: irregular periods, acne, facial hair, weight gain, or difficulty conceiving. That made many patients enter the healthcare system through gynecology, usually when menstrual, reproductive, or visible hormonal symptoms became hard to ignore.

The shift from Polycystic Ovary Syndrome to Polyendocrine Metabolic Ovarian Syndrome encourages clinicians to look earlier, wider, and more systematically at the condition.

A Wider Starting Point

The old name placed the ovary at the center of the condition. PMOS keeps ovarian function in the picture, but it widens the diagnostic lens to include the hormone and metabolic systems that are often involved from the start. This distinction matters because the condition is not defined by harmful ovarian cysts. In fact, ovarian cysts are not required for diagnosis, and some women with PCOS may not show polycystic ovaries on ultrasound at all. The newer name, therefore, helps move diagnosis beyond a scan-based or ovary-only understanding, and closer to how the condition actually presents and manifests itself in the body.

From Period Problem To Whole-body Assessment

With PMOS, diagnosis should become less dependent on ultrasound and more attentive to the full clinical pattern. Doctors will still look at irregular or absent periods and signs of high androgen levels, such as acne, excess facial or body hair, hair thinning, and raised testosterone levels, where tested. But the newer framing should also make metabolic screening routine, especially for insulin resistance, type 2 diabetes risk, blood pressure, cholesterol, obesity, sleep apnea, and fatty liver-related concerns. WHO describes PCOS as a chronic metabolic condition that can persist beyond the reproductive years, with symptoms and risks varying from person to person.

PMOS: Why This Change Could Reduce Missed Diagnosis

The scale of underdiagnosis is large. It is estimated that PCOS affects 10–13% of reproductive-aged women, while up to 70% of affected women worldwide may not know they have the condition. A name that leads with “polyendocrine” and “metabolic” may help clinicians connect symptoms that were previously treated separately: a dermatologist sees acne, a gynecologist sees irregular periods, an endocrinologist sees insulin resistance, and a mental-health professional sees anxiety or poor quality of life.

What Needs To Change Now

The diagnosis is not changing into a different disease. The condition remains the same, but the way it is understood may become broader and more accurate. The real opportunity lies in better recognition: fewer patients being told their symptoms are only about cysts, weight, periods or fertility, and more patients being assessed for the long-term hormonal and metabolic risks that can come with the condition.

For this shift to matter, awareness must grow across the medical fraternity and among patients, so PMOS is approached as a multi-system condition; symptoms are recognized earlier, and care becomes more connected from the beginning.

(Written by Dr. Rashmi Dharaskar, Sr. Consultant Obstetrics and Gynaecologist at Surya Mother & Child Super Specialty Hospital).

When Indian summers touch 48 degrees, it’s no longer just uncomfortably hot—it’s a serious public health challenge. Extreme heat affects everything from hydration levels in the body to digestion, the health of your skin, heart, and even mental well-being. Surviving (and staying healthy) through such brutal temperatures requires 360-degree body care, not just an extra glass of water or switching on the AC.

Dr P. Venkata Krishnan, Senior Consultant & Director—Internal Medicine, Narayana Hospital, Gurugram, in an interview with Health and Me, shared a complete and practical survival plan to help your body cope with the extreme Indian summer—inside and out.

Hydration: Go Beyond Plain Water

In intense heat conditions, your body loses water and electrolytes very quickly through sweat. Electrolytes help carry water to the blood and tissues. Hence, drinking only plain water in summer may not suffice. Try sipping water consistently at regular intervals instead of gulping large quantities at once. Electrolyte-rich fluids like coconut water, lemon water with a pinch of salt, or buttermilk are healthy, affordable options to soothe parched throats. Avoid excess caffeine, colas, and alcohol, as they increase dehydration; if you must indulge, have a glass of water before your coffee or alcoholic drink.

Pro tip: Check your urine colour—dark yellow is a warning sign of dehydration.

Eat Light, Cool, and Smart

Our digestive systems are also tired in extreme summers. Spicy, heavy, and oily foods generate more internal heat, which puts an additional burden on digestion. Opt for seasonal fruits like watermelon, muskmelon, papaya, and berries instead of chips and snacks.

To ease digestion, add items like curd, rice, cucumber, and bottle gourd to your meals. Avoid red meat and fried foods during peak summer days. Smaller, lighter meals are easier for the body to process in extreme heat. Find ways to increase hydration through fruits and vegetables in your food too, apart from water intake.

Protect Your Skin from Heat Damage

Heat doesn’t just tan your skin—it accelerates ageing, causes pigmentation, and triggers rashes. Incorporating a summer skincare regimen can help prevent damage to your skin.

1. Use a broad-spectrum sunscreen daily, even if you’re indoors.
2. Wear loose, breathable cotton or linen clothing.
3. Take cool (not ice-cold) showers to soothe overheated skin.
4. Seek medical advice for prickly heat, fungal infections, or sudden rashes—they thrive in sweaty conditions.

Mind Your Heart and Blood Pressure

Extreme temperatures put additional stress on the cardiovascular system, especially in people with hypertension, diabetes, or heart conditions. There are just a few things to bear in mind. When the temperature outside sizzles, avoid stepping outdoors for prolonged periods, especially between 12 pm and 4 pm, when the sun beats down mercilessly.

Take all prescribed medications exactly as advised—don’t skip doses even if you experience heat-induced nausea. If you feel dizzy or experience palpitations or severe fatigue, consult your doctor as soon as possible. Heat exhaustion can silently progress to heatstroke, which is a medical emergency.

Smart Cooling at Home and Work

Air conditioning is helpful, but overexposure can lead to dry skin, headaches, and respiratory discomfort. However, since the emphasis is more on cooler environments in summer, there are a few ways to avoid overexposure to AC.

Once every two or three hours, step away from your desk for a few minutes. Walk or stand, and sip some water. Open windows, if possible, to avoid thermal shock. Set AC temperatures between 24 and 26 degrees, despite the urge to cool the surroundings further. Use fans and cross-ventilation whenever possible, relying a little less on air conditioning in the process. Never move directly from extreme heat into freezing AC environments, or vice versa, as it can impact your body suddenly.

Sleep & Mental Well-being Do Matter

Poor sleep due to heat can increase irritability, anxiety, and fatigue. Include some calming activity before bedtime. Put away screens, as they radiate heat too. Some tips to help you sleep better:

1. A lukewarm shower before bed.
2. Well-ventilated bedrooms.
3. No heavy dinners or eating late at night; ideally, finish dinner before 9 pm, leaving a gap of a couple of hours afterwards before going to sleep.
4. Mindful slow breathing or short meditation helps control heat-related restlessness.

Special Care for Vulnerable Groups

Children, elderly individuals, pregnant women, and outdoor workers are at higher risk of heat-related health concerns. They should particularly ensure that they hydrate more frequently.

1. Watch for signs like dry mouth, lethargy, confusion, or reduced urination. Seek a doctor’s advice if needed.
2. Include cooling foods to prevent dehydration and encourage lighter, frequent meals instead of full, heavy meals.
3. Never leave children or pets inside parked vehicles or in spaces without ventilation—even for a few minutes.

A holistic approach covering hydration, nutrition, skincare, heart health, and mental well-being can help your body adapt and stay resilient. Extreme heat is not “just a bad summer." Treat it seriously, listen to your body, and make smart daily choices, because protecting yourself from the heat today prevents long-term health problems tomorrow.