How Old Are Your Organs? New Study Links Organ Aging to Disease Risk

Updated Mar 19, 2025 | 05:00 PM IST

SummaryThe blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
How old are your organs?

Credits: Canva

A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

  • Heart
  • Blood vessels
  • Liver
  • Immune system
  • Pancreas
  • Kidneys
  • Lungs
  • Intestines
  • Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

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H1N1 Virus Surge In Delhi : Should You Get A Flu Vaccine Now?|Explained

Updated Aug 24, 2026 | 09:04 PM IST

SummaryDoctors stressed that annual influenza vaccination remains an important tool to reduce the risk of severe illness, complications and hospitalization, particularly among people at higher risk.
H1N1 Virus Surge In Delhi : Should You Get A Flu Vaccine Now?|Explained

Credit: iStock

Delhi-NCR is witnessing a sharp increase in seasonal influenza, with 1,777 confirmed H1N1 (swine flu) cases reported out of 2,392 total Influenza A cases.

According to data from the National Centre for Disease Control (NCDC), the corresponding period last year recorded just 229 H1N1 cases.

Several hospitals in the national capital have reported a significant increase in cases. However, so far there have been no reports of patients requiring ICU care or ventilator support.

“Delhi is fully prepared to deal with the present health situation. There is no shortage of beds, doctors, medicines or essential medical equipment, and every patient will receive timely and appropriate treatment,” health authorities said.

Is The H1N1 Surge Due To A New Strain?

The Indian Council of Medical Research (ICMR) has confirmed that the current surge is not due to a new strain of H1N1 and has advised people to follow precautions rather than panic, PTI reported.

According to the apex research body, the Influenza A (H1N1) viruses currently circulating in India belong to the A/Missouri/11/2025 (H1N1)pdm09-like virus strain.

“These viruses belong to clade 6B.1A.5a2a, subclade D.3.1.1, and have been in circulation since 2025,” the ICMR said. “Seasonal influenza, including H1N1, is mostly self-limiting,” it added.

Is The Current H1N1 Strain Covered By The Flu Vaccine?

The ICMR said the influenza strains currently circulating in India are well matched with the vaccine strains recommended for the Northern Hemisphere.

For both egg-based vaccines and cell culture-, recombinant protein- or nucleic acid-based vaccines, the World Health Organization (WHO) recommends an A/Missouri/11/2025 (H1N1)pdm09-like virus.

HealthandMe spoke to experts to understand whether people should consider getting a flu vaccine amid the current rise in H1N1 cases and who should prioritise vaccination.

Doctors stressed that annual influenza vaccination remains an important tool to reduce the risk of severe illness, complications and hospitalization, particularly among people at higher risk.

“Since the 2009 H1N1 pandemic, H1N1 is no longer given as a separate standalone vaccine. The H1N1 strain is included in the regular seasonal influenza vaccine, whether trivalent or quadrivalent. Therefore, getting the recommended annual flu vaccine also protects against H1N1,” Dr Tushar Tayal, Associate Director, Internal Medicine, CK Birla Hospital, Gurugram, told HealthandMe.

Who Should Prioritize Flu Vaccination?

The seasonal influenza vaccine is recommended every year for everyone aged six months and above. Doctors say vaccination is particularly important for:

  • Pregnant women
  • Older adults
  • Young children
  • Healthcare workers
  • People with diabetes
  • People with asthma
  • People with heart disease

The Indian Medical Association (IMA) advises that the inactivated influenza vaccine can be given to the above high-risk groups.

“The live attenuated influenza vaccine (intranasal spray) can be given only to persons aged 2-49 years (not to pregnant females),” as per the IMA.

“The H1N1 flu vaccine is typically administered annually before flu season, around October, as a single intramuscular dose at clinics, pharmacies or hospitals,” Dr Atul Gogia, Head, Infectious Diseases, Sir Ganga Ram Hospital, New Delhi, told HealthandMe.

For most adults and children aged over nine years, one dose each year is sufficient. However, children aged six months to eight years who are receiving the flu vaccine for the first time may require two doses at least four weeks apart. After the initial vaccination, one annual dose is generally sufficient.

Should You Get The Flu Vaccine Now?

In India, influenza vaccination is ideally taken ahead of periods when flu activity tends to increase, particularly during the monsoon and winter months. The vaccine is available through hospitals, clinics and vaccination centers.

With H1N1 cases currently rising in Delhi-NCR, people who fall into high-risk groups may particularly benefit from discussing vaccination with their doctor.

Can The Flu Vaccine Prevent H1N1 Completely?

“While the shot drastically reduces hospitalizations and complications, its primary limitation is that it does not offer 100% protection against infection, nor does it cover non-influenza viruses. However, even if contracted, vaccination significantly softens the disease’s severity,” Dr Atul said.

Dr Tayal also explained that vaccine effectiveness can vary from season to season, depending on how well the vaccine strains match the influenza viruses circulating at the time.

Why Is Annual Flu Vaccination Needed?

According to Dr Tayal, annual vaccination can reduce the risk of severe influenza, complications, hospitalization and flu-related deaths. However, it does not provide complete protection against every respiratory infection.

The flu vaccine protects against influenza viruses, including H1N1, but does not prevent illnesses caused by other viruses or bacteria.

Along with annual vaccination, experts advised people to:

  • Maintain good hand hygiene
  • Follow respiratory etiquette, including covering the mouth and nose when coughing or sneezing
  • Stay home when unwell
  • Avoid close contact with others when experiencing flu-like symptoms

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Student Mental Health Needs More Than A Counsellor

Updated Aug 24, 2026 | 02:00 PM IST

SummaryStudent mental health requires more than counselling, with universities needing broader support systems, early intervention, mental health education and environments that address academic and social pressures.
Student Mental Health Needs More Than A Counsellor

Credit: AI

Higher education has changed far more than we often acknowledge. Universities are no longer simply places where students earn degrees. They are where young adults spend some of the most formative years of their lives, away from familiar support systems, making independent decisions, navigating uncertainty and, for many, encountering the first signs of a mental health condition. That quiet shift has expanded the role of educational institutions in ways that were never envisaged a decade ago.

The conversation around student wellbeing has evolved alongside this change. Mental health is no longer viewed as a subject to be discussed only after a crisis. Students are speaking more openly, parents are asking different questions, faculty members are becoming more aware and institutions are recognising that emotional wellbeing is closely linked to learning, participation and long term outcomes. This change deserves to be welcomed because it has helped move mental health from the margins of campus life to the centre of institutional responsibility.

Why A Counsellor Alone Is Not Enough?

Yet one assumption continues to shape much of this conversation. The presence of a counsellor is often seen as evidence that a campus is equipped to support student mental health. Counsellors remain indispensable and, for many students, they provide exactly the support that is needed. The challenge arises when counselling is expected to fulfil every role within a mental healthcare system.

Every effective healthcare system is built on layers of expertise. A physician does not replace a surgeon. A laboratory does not replace a diagnosis. Emergency care does not replace rehabilitation. Mental healthcare should be viewed no differently. Counselling is often the first point of contact, but the needs of students do not end there.

Some require structured therapy, others psychiatric evaluation, some ongoing clinical monitoring, and a few immediate crisis intervention. A mature campus mental healthcare system should be equipped to respond across this entire spectrum. The conversation should therefore move beyond whether campuses have counsellors to whether they have a system capable of supporting every stage of care.

Also read: Why People With Mental Health Conditions Are More Likely To Struggle With Tobacco Addiction

Building A Comprehensive Campus Mental Healthcare System

Encouragingly, public policy is beginning to recognise this changing reality. The University Grants Commission’s draft guidelines on mental health and wellbeing for higher educational institutions, with recommendations on counsellor ratios, dedicated wellbeing centres, round the clock helplines and mechanisms for early identification of distress, mark an important step in strengthening institutional support. More importantly, they open the door to a broader conversation on what comprehensive mental healthcare within higher education should look like over the coming years.

Building such a system requires looking beyond individual appointments. One of the most valuable lessons from developing healthcare services is that outcomes are rarely determined by the first consultation alone. They depend on how seamlessly care continues afterwards. If a counsellor recognises that a student needs specialised assessment, how quickly can that happen?

Also read: Lindsay Clancy Trial: What Postpartum Psychosis Really Looks Like, From A Survivor

If medication becomes necessary, is psychiatric care available without delay? If a student experiences a crisis outside campus hours, is there a clearly defined pathway to immediate support? If treatment begins, who ensures continuity during semester breaks or after the student returns home? These are not administrative questions. They are questions that shape recovery.

A comprehensive campus mental healthcare ecosystem should therefore bring together different levels of expertise rather than rely on one profession alone. Counsellors, clinical psychologists, psychiatrists, experienced mental health specialists and emergency support services each play a distinct role. Their contribution becomes most effective when they work as part of an integrated network with clear referral pathways, shared clinical responsibility and continuity of care that extends beyond the physical boundaries of the campus.

Prevention And Early Intervention Matter Too

Also read: Sugar Rationing In First 1,000 Days Linked To Lower Depression, Cancer Risk In Adulthood

Equally important is recognising that mental healthcare should not begin only after a student seeks help. Institutions have long understood the value of preventive healthcare through regular physical health assessments, vaccination drives and awareness programmes. Mental health deserves the same thoughtful approach.

Periodic, voluntary mental health check ins, appropriate screening, trained faculty and peer support networks, backed by specialist expertise, can help identify concerns early while respecting privacy, dignity and informed consent. Early recognition is not about labelling students. It is about ensuring that support reaches them before distress becomes disabling.

Technology can strengthen this ecosystem, but it cannot replace it. Digital consultations, secure follow up, coordinated records and access to specialists across locations can make care more continuous, particularly for students studying away from home. Their real value lies in connecting different parts of the system rather than functioning as isolated solutions.

Mental Healthcare As Part Of The Institutional Foundation

The quality of a university has traditionally been measured through its academic standards, faculty and research. Increasingly, it will also be measured by how well it supports the people who make learning possible. Mental healthcare deserves to be seen as part of that institutional foundation, not as an additional welfare service that sits alongside education.

The conversation has already moved beyond whether student mental health matters. The next step is to recognise that no single professional, however skilled, can meet every need that students may bring with them. Every campus needs more than a counsellor because every student deserves access to a mental healthcare system that is prepared not only to listen, but also to respond, support and care through every stage of that journey.

By Dr. Jothi Neeraja, Founder, Chairwoman and Managing Director, Maarga Mindcare

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Sugar Rationing In First 1,000 Days Linked To Lower Depression, Cancer Risk In Adulthood

Updated Aug 24, 2026 | 11:26 AM IST

SummaryThe twin studies suggest that the first 1,000 days may be an important window in which nutrition can shape health much later in life. But more research is needed to understand exactly how early-life sugar exposure influences mental health, cancer risk and biological ageing.
Sugar Rationing In First 1,000 Days Linked To Lower Depression, Cancer Risk In Adulthood

Credit: iStock

Anxiety and depression are major concerns in adulthood, but could nutrition during the earliest stages of life influence health decades later? Two new studies suggest that lower sugar exposure during the first 1,000 days of life may be associated with lower risks of anxiety, depression and even several cancers later in life.

The findings, from studies published in Translational Psychiatry and PNAS point to the potential long-term effects of early-life nutrition. However, the findings do not mean that restricting sugar in infancy directly prevents these diseases.

Sugar Rationing And Mental Health

A 2026 study led by researchers from the University of Surrey, UK, analyzed 46,448 people born between October 1951 and March 1956.

Participants were grouped according to how long they were exposed to sugar rationing: from in utero only to 24 months. People conceived after food rationing had ended served as the main comparison group.

Researchers also analyzed brain MRI data from 5,990 participants.

Lower Risk Of Anxiety And Depression

Compared with people conceived after rationing ended, those exposed to sugar rationing for the three longest periods had significantly lower hazards of both anxiety and depression.

  • Shorter-exposure groups did not show significant differences.
  • The associations were stronger in women.
  • Adult sugar intake was broadly similar across groups, at about 58–59 g/day of free sugar and 122–124 g/day of total sugar.

When later-life sugar intake was considered, the association with anxiety persisted among those exposed throughout pregnancy and the first two years of life, while the association with depression weakened and was no longer statistically significant.

Further, MRI analysis found differences across rationing groups in 80 of 139 gray matter regions. Analysis identified 11 regions that differed from participants conceived immediately after rationing ended, including the brainstem, occipital fusiform gyrus and several cerebellar regions.

Sugar And Cancer Risk

A separate study published in PNAS examined whether sugar exposure during the first 1,000 days could influence cancer risk later in life.

Researchers from China Agricultural University and the University of Cambridge used the abrupt end of UK sugar rationing in September 1953 as a natural experiment. The analysis included 64,761 UK Biobank participants born between 1951 and 1956.

Compared with those whose first 1,000 days were not affected by rationing, participants exposed to rationing showed lower incidence of several cancers:

  • Liver/intrahepatic bile duct cancer: 69% lower
  • Prostate cancer: 52% lower
  • Lung cancer: 41% lower
  • Rectal cancer: 40% lower
  • Breast cancer: 36% lower

The researchers identified two possible pathways behind the association.

How Could Early Sugar Exposure Matter?

  • Long-term dietary habits: People exposed to rationing consumed less sugar, ate smaller quantities and had healthier, more diverse diets even five decades later, suggesting that early-life exposure may influence lasting food preferences.

  • Biological ageing: The rationed groups had longer leukocyte telomeres, equivalent to about 2.2 fewer years of biological ageing, along with lower levels of Granzyme B, a marker linked to chronic immune activation.

Sugar's Link With Mental Health And Cancer

Sugar is an important source of energy for the brain, and very low blood glucose can impair brain function. However, excess sugar intake has also been associated with metabolic problems that can affect long-term health.

When it comes to cancer, sugar does not directly cause cancer, and cutting out all sugar does not “starve” cancer cells. Both healthy and cancer cells use glucose for energy.

However, consistently consuming excessive amounts of added sugar can contribute to weight gain and obesity, which are established risk factors for several cancers.

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