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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
A healthy liver does not ask for much, just the right nutrition. (Photo credit: AI generated)
Many people follow what appears to be a reasonable eating pattern—meals at irregular hours, a light breakfast skipped in the name of time, and dinner pushed late into the evening. Yet the body, particularly the liver, does not respond well to such improvisation. What feels like a manageable routine on the surface can quietly accumulate into something more serious over months and years. The liver needs a consistent flow of nutrients to do its job, which includes managing blood sugar, breaking down fats, and supporting digestion. Long gaps between meals disrupt that rhythm.
Dr Babu U V, Director of R&D, Research & Development Centre, Himalaya Wellness Company, in an interview with Health and Me, spoke about the early symptoms of liver damage and explained how herbs can play a role in reversing it.
Before most people realise that something is wrong with their liver, they may already be experiencing symptoms that indicate potential liver issues. These symptoms may include fatigue, bloating, digestive discomfort, or feeling heavy after eating. Most of the time, these signs are dismissed as minor concerns.
When these issues are ignored or go unnoticed, it becomes difficult to recognise that the liver may be weakened by stress and not functioning optimally. If these problems persist over time, fat can begin to accumulate in the liver, along with other types of metabolic imbalances throughout the body.
To restore balance in the body, small changes in daily habits can lead to significant improvements. For example, eating at regular intervals helps the body maintain a consistent metabolism. Similarly, having lighter dinners and avoiding late-night eating can support better digestion and metabolism of food.
Some herbs commonly used in Indian households and traditional medicine may help support the liver’s healing process, especially when it is under stress.
Each of these herbs works in different ways—some aid digestion, while others help neutralise free radicals and reduce oxidative stress—thereby supporting a healthier lifestyle.
The liver is highly resilient; however, it requires consistent care. An irregular dietary pattern may not affect the liver immediately, but over time it can have a significant impact. Paying attention to simple habits—such as when and how you eat—and choosing foods that support liver health can go a long way in maintaining optimal liver function over the long term.
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World Liver Day 2026 is observed every year on April 19 to raise awareness of the importance of liver health, focusing on preventing diseases such as cirrhosis and fatty liver through healthy lifestyles.
The liver is a key organ that filters blood, breaks down food, stores energy, and keeps the human body in balance.
However, rising metabolic risk factors, including high blood sugar and obesity, are increasingly driving cases of metabolic dysfunction-associated steatotic liver disease (MASLD).
Nearly one-third of the global adult population today lives with MASLD, which can remain asymptomatic for years but turn into deadly scarring (fibrosis), cirrhosis (advanced fibrosis and loss of some of the liver function), or even liver cancer.
The European Association for the Study of the Liver (EASL) launched World Liver Day in 2010. The day was established on April 19 to commemorate the EASL's founding in 1966.
This year, 2026, the World Liver Day theme is “Solid Habits, Strong Liver”. It emphasizes building consistent lifestyle habits, such as balanced diet, regular exercise, avoiding alcohol, and routine check-ups, to strengthen liver health and prevent diseases.
From filtering toxins to aiding in digestion and metabolism, the liver silently performs over 500 crucial functions in the body. The organ is also blessed with the ability to regenerate itself.
Yet data shows that 2 million lives worldwide are lost each year to liver disease. About 1.5 billion people suffer from chronic liver disease.
MASLD, formerly known as non-alcoholic fatty liver disease (NAFLD), has emerged as the most common liver condition worldwide. These patients suffer from either obesity, diabetes, metabolic syndrome, hypertension, or cholesterol problems.
According to a recent study published in The Lancet Gastroenterology & Hepatology journal, MASLD affected 1.3 billion people around the globe in 2023.
The alarming study estimates the numbers to further spike by over 38 percent to reach 1.8 billion cases by 2050, causing substantial health and economic impacts worldwide.
MASLD remains one of the most prevalent and rapidly growing liver conditions worldwide, with its prevalence marking a 143 percent increase between 1990 and 2023.
Also read: Why Regular Scans Are Crucial for Liver Cancer Patients: Doctors Explain
People with obesity, diabetes, central or abdominal fat, dyslipidemia, hypertension, and insulin resistance are more likely to have MASLD. Obesity is the strongest risk factor, with the likelihood rising steeply from overweight to severe obesity.
Other signs to watch for include
Certain lifestyle choices can accelerate liver damage, such as:
Early screening and detection are key to prevent irreversible stages. Yet liver disease can be prevented with lifestyle changes such as:
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A growing number of young professionals aged 18 to 30 are being diagnosed with Irritable Bowel Syndrome (IBS), a trend that is linked to the pressures and habits of modern life, said health experts today.
World Irritable Bowel Syndrome Day is held annually on April 19th to raise global awareness, reduce stigma, and support the roughly 700 million people worldwide suffering from the condition.
According to health experts, the combination of long hours in the office, irregular diets, high-stress levels, and lack of physical activity has paved the way for a lifestyle that is making young adults increasingly susceptible to developing symptoms related to their gut.
Speaking to HealthandMe, Dr. Nidhi Rawal, Consultant - Pediatric Gastroenterologist and Hepatologist, Rainbow Hospital, explained the major risk factors that are taking a visible toll on digestive health.
1. Chronic stress
Young professionals are faced with a fast-paced job environment full of obstacles and demands that they experience daily, along with performance pressure and increased digital overload; all of these factors can hurt the gut-brain axis.
When the gut-brain axis becomes disrupted, the motility and sensitivity of the digestive system can be affected, producing gut-related symptoms, such as abdominal discomfort, excessive gas, and changes in bowel movements.
2. Dietary habits
The increased reliance on processed foods, increased frequency of ordering takeout and fast food, excessive caffeine consumption, and irregular meal schedules can disrupt digestion and alter the balance of healthy vs unhealthy microbiota in the digestive tract.
3. Skipping meals
Skipping meals or eating a late dinner can also raise risk of IBS, and worsen symptoms.
4. Lack of physical activity
Being sedentary for long periods of time results in slowing the digestion process and therefore increases the risk of constipation and bloating.
5. Poor sleeping habits
Common among people in this age group, this also affect hormones and digestion negatively.
6. Better access to diagnostic tests
Better access to diagnostic tests and awareness are leading to an increase in diagnosis of the condition, that can also enable faster treatment and early recovery.
What Is IBS?
Irritable Bowel Syndrome (IBS) is a common but often overlooked gastrointestinal disorder, and less than 15 per cent get diagnosed.
Common symptoms include
IBS remains undiagnosed for many years as people tend to normalize these symptoms over time or attribute them to "something they ate" or everyday stresses.
One reason for this delay in being diagnosed is that the symptoms occur intermittently.
It is also important to note that the presentation of these symptoms is inconsistent and unpredictable; there may be episodes where the IBS can last many days, and then completely resolve, thus providing a false sense of relief.
Therefore, many individuals choose to delay consulting with a physician due to their belief that the symptoms they are experiencing are not serious.
Another contributing factor is that there is still a degree of reluctance or discomfort associated with discussing problems related to the gastrointestinal tract openly; this only further complicates under-reporting statistics.
IBS is a functional disorder. Therefore, routine diagnostic testing will not reveal any visible abnormalities.
Many patients may assume that the symptoms they are experiencing are not "real" or are not significant enough to warrant seeking medical attention, even though the discomfort they experience can be quite significant and affect their daily lives.
To treat IBS effectively, those suffering from it need to adopt some lifestyle changes, such as
Regular mealtimes,
A balanced diet,
Exercise,
Stress reduction.
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