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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
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Kidneys are extraordinary organs that perform critical tasks on a continual basis, e.g., filtering out waste, keeping electrolytes balanced, controlling blood pressure, and providing metabolic stability.
However, many people don’t pay enough attention to keeping their kidneys healthy until they discover that substantial damage has already happened.
Some of the most prevalent and underestimated threats to kidney functioning include uncontrolled blood pressure, chronic anxiety, and unhealthy living.
Hypertension (high blood pressure) is considered one of the most prevalent causes of CKD (chronic kidney disease) worldwide.
The kidneys need the support of a complicated design of tiny blood vessels to carry out their task of removing waste from the bloodstream. An ongoing and increased blood pressure level will slowly harm these small blood vessels by reducing their ability to function normally. As time passes, this injury will result in scar formation of the kidney tissue, causing a continual decline in the kidney’s ability to filter.
Hypertension is known as a silent killer because it frequently has no symptoms for many years. By the time someone experiences symptoms of high blood pressure, their kidneys may have already been damaged for a considerable period.
Chronic stress is often overlooked as an indirect cause of kidney damage. When we are under chronic stress, our sympathetic nervous system is activated, and the amount of stress hormones (cortisol and adrenaline) in our bodies increases.
These physiological changes lead to prolonged increases in blood pressure and blood glucose; both of these risk factors are bad for our kidneys. Chronic stress may cause people to engage in unhealthy coping strategies like poor diet, smoking, consuming alcohol, or not being physically active, which also increases their risk of kidney damage.
Our long-term kidney function is largely determined by lifestyle choices, including our dietary habits. Diets high in sodium, processed foods, and unhealthy fats increase the probability that you will develop hypertension, metabolic disorders, or some combination of both of these, which puts even more strain on your kidneys.
The sedentary lifestyle associated with obesity, insulin resistance, and cardiovascular disease are all significant contributors to chronic kidney disease. Dehydration, taking large amounts of over-the-counter medications (especially NSAIDs), and using tobacco products are all additional risk factors for progressive loss of kidney function.
Many of these risk factors can be addressed through prevention.
Regular monitoring of blood pressure, using mindfulness and other methods to manage stress levels, and maintaining a healthy diet full of fruits, vegetables, and whole grains will all help to reduce the strain on your kidneys.
Regular health screenings for people who have some of the above-mentioned risk factors (e.g., diabetes, high blood pressure, etc.) will give people an opportunity to identify problems early, giving them time to adjust their lifestyle or possibly seek some other type of treatment (e.g., taking medication).
Gaining and maintaining awareness of what contributes to the health of the kidneys can help protect the kidneys.
Gaining awareness of and taking action against hidden risks, such as high blood pressure or chronic stress, and making positive changes to your lifestyle will help maintain kidney function and minimize the likelihood of developing long-term complications in the future.
Early intervention is the most effective method for protecting the health of your kidneys.
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India is surely winning the battle against malaria. However, the disease is still around. Medicines and nets help a lot, but doctors point to something else. They say the real cure starts before you even get sick. It all comes down to keeping your local area totally clean.
This fever only spreads through female Anopheles mosquitoes. They do not need big ponds to multiply. A little dirty water trapped inside an old tyre, a thrown-away plastic cup, or a coconut shell is all they need. That is where the cycle of malaria starts. Within days, larvae turn into mosquitoes, and the infection begins to move through nearby homes. This is why many doctors put it plainly. Treating a patient comes later. Stopping the mosquito from breeding is the foundation of the battle against malaria, and that depends on everyday cleanliness by everybody residing in each lane and building.
The official health data brings major relief. Malaria is finally losing its grip. Fresh WHO reports prove this fact. In 2017, India struggled with nearly 64 lakh cases. But the figures show a steep fall in the number of cases by 2023. The total patient count stood at just 20 lakh. We are looking at a clear 69 percent drop in a very short time. Seeing this huge improvement, the WHO took India off its critical 'High Burden to High Impact' list in 2024.
Data released by the government of India tells a similar story. Figures from the National Center for Vector-Borne Diseases Control under the Union Health Ministry show a decline in the number of deaths by more than 78 percent between 2015 and 2023. The target now is clear. The government has set a very clear target. They want malaria cases to hit zero by 2027. After that, the final goal is to wipe out this disease from the entire country by 2030.
We are winning this fight, but the danger is still far from over. Cover your water tanks properly. Clean the open drains. Do not let rainwater collect near your house. These small daily habits easily stop the disease from spreading.
However, the health department alone cannot achieve this massive target. Fogging and spraying of chemicals done by municipal bodies only kill adult mosquitoes that are already flying. The fight is local. If water tanks are shut tight, drains are not clogged, and garbage isn’t left to collect rainwater, the danger drops quickly.
When a society maintains clean surroundings, it naturally destroys the breeding grounds for mosquitoes. If the mosquitoes cannot breed, the chain of infection breaks automatically. As India moves closer to its 2030 malaria-free goal, keeping our streets, parks, and homes clean is no longer just a civic duty. It is our absolute first line of medical defense against a deadly disease.
Take-out food often comes in black plastic containers, but these are far from safe for your health. (Photo credit: iStock)
Plastic containers have been discouraged for a long time now, especially for heating food or storing hot food. Studies have associated this habit with a heightened risk of cancer, but now an expert has specifically spoken about black plastic containers and what makes them worse for you. According to Dr Rakesh Kumar Sharma, Senior Consultant Medical Oncologist at M | O | C Cancer Care & Research Centre, Gurugram, cooking or heating food in black containers could be very harmful to your body. Read on to find out how.
Dr Sharma, in an interview with Health and Me, said that cooking food in black plastic receptacles could lead to greater amounts of certain chemicals making their way into your body; however, there currently exists no scientific evidence confirming that this daily activity increases your risk of cancer.
Dr Sharma explained that black takeaway containers usually consist of recycled plastics, such as e-waste, and can contain flame retardants, BPA, phthalates, etc. When heated in contact with food, especially if the food is hot, fatty, or acidic, more chemicals could potentially make their way into the food from the container. In this way, it may, over time, heighten your risk of developing a malignant tumour.
Black containers are coloured using carbon black, which is included in Group 2B of possible human carcinogens according to IARC, as shown in both animal and limited human research. Moreover, recycled black plastics could contain polycyclic aromatic hydrocarbons and decaBDE, which have shown carcinogenic effects in experiments. This makes black plastic containers worse than other coloured counterparts. Yet, heating food in a plastic container of any colour is not deemed safe.
Do studies verify the side effects of heating food in plastic containers?
Experimental studies conducted in laboratories on microwaveable plastic receptacles reveal the migration of tens of chemicals and millions of microplastics per litre of the food simulant. However, a recent study in 2024 reported that containers labelled as microwave-safe in Korea adhered to contemporary safety standards for these levels, and total exposure fell within safe limits.
Leading cancer associations have confirmed that the usage of plastic packaging, even in microwave applications, has not been linked with increased cancer risks in humans, although there is ongoing research in areas such as black plastics. However, precautionary measures are suggested by experts as a better strategy due to the difficulties of directly studying long-term, low-level exposure to chemical compounds.
How to reduce cancer risk?
When it comes to reducing cancer risk, most doctors recommend quitting smoking and limiting alcohol intake. However, Dr Sharma listed some basic kitchen and eating habits that may come to your rescue:
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