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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
Imbalanced thyroid can lead to weight fluctuations. (Photo credit: iStock)
World Thyroid Day is observed on 25 May every year. This day aims to spread awareness about thyroid disorders, their symptoms, and management options that can help women. However, one concern that continues to linger with respect to thyroid disorders is why they occur more often in women. Hormonal changes, lifestyle factors, and a higher risk of autoimmune conditions can increase the risk of thyroid problems in women. Yes, that’s right! Hence, women should ensure they go for timely health check-ups. Here, an expert highlights vital tips for women. Read on to know more about this and seek timely help. Remember, thyroid problems should not be left untreated at all.
In an interview with Health and Me, Dr Shruti Kotangale, Consultant Gynaecologist, Obstetrician, and Infertility Expert at AIMS Hospital, Dombivli, explained why thyroid problems are more common among women. Read here to know how gender makes a difference.
Thyroid disorders are rising among many women. The thyroid is a small gland in the neck, but it plays a critical role in controlling metabolism, energy levels, and maintaining hormonal balance. Women can suffer from thyroid problems because of frequent hormonal changes during puberty, pregnancy, and menopause. These changes can impact thyroid health. Lifestyle factors such as stress, poor diet, and lack of sleep can also worsen thyroid imbalance. Hence, women are at a higher risk of suffering from autoimmune conditions, where the body’s immune system attacks the thyroid gland.
Conditions such as hypothyroidism (underactive thyroid) and hyperthyroidism (overactive thyroid) are commonly seen in women. Hypothyroidism occurs when the thyroid gland is underactive. Symptoms can include tiredness, weight gain, dry skin, hair fall, constipation, feeling cold, a slow heartbeat, and low mood or depression. Hyperthyroidism occurs when the thyroid gland becomes overactive, and women may experience weight loss, a fast heartbeat, sweating, anxiety, tremors, irritability, frequent bowel movements, and even difficulty sleeping. Women are advised to seek immediate medical attention and manage these symptoms without any further delay.
Thyroid disorders may be concerning, but they are manageable with appropriate care and management tips as recommended by experts. Both hypothyroidism and hyperthyroidism can be managed with timely diagnosis, regular screening, and taking medications as suggested by the doctor. It is also important to eat a balanced diet, exercise daily for at least 30 minutes, get sound sleep at night, and de-stress through yoga and meditation. This World Thyroid Day, the focus should be on awareness, regular check-ups, and taking small steps to stay healthy and manage thyroid problems. Moreover, follow the doctor’s advice and do not self-medicate, as doing so can be risky.
So ladies, this World Thyroid Day, make an effort to know more about this group of disorders that affects your gender more often than men. Be it fatigue, mood swings, or weight fluctuations, it is imperative to know the early warning signs of this condition in order to work towards a more preventive approach.
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IBD or Inflammatory Bowel Disease is a growing health concern worldwide - particularly amongst young adults. The two main types of IBD are Ulcerative Colitis and Crohn’s disease. However, these can be confused because they share symptoms.
Some of these are abdominal pain, diarrhea, fatigue, and weight loss. They affect the digestive tract differently, thus also have different complications and treatment plans. It is important to understand these differences so that patients may seek out timely diagnosis and better disease management.
1. Different Parts of the Digestive Tract Are Affected
Ulcerative Colitis is limited to the colon and rectum. Inflammation begins in the rectum and spreads continuously upwards. In Crohn’s disease, any part of the digestive system can be impacted. Including the mouth, esophagus, stomach, small intestine, and colon. However, it is most commonly the small intestine that is involved in Crohn’s disease.
2. Inflammation Pattern is Different
In ulcerative colitis, inflammation is continuous. There are no healthy gaps in between the affected areas. Crohn’s disease causes patchy inflammation. Meaning, there are sections of healthy tissue known as “skip lesions”.
3. Crohn’s Disease causes more serious damage
Ulcerative colitis affects only the innermost lining of the bowel. Crohn’s disease, on the other hand, can involve all layers of the intestinal wall. This increases the risk of complications such as fistulas, bowel obstruction, and intestinal narrowing.
4. Symptoms May Look Similar, But Often Differ
Both conditions can cause diarrhea, abdominal cramps, fatigue, and unintended weight loss. However, bloody stools are more common in ulcerative colitis. Crohn’s disease may also cause mouth ulcers, severe nutritional deficiencies, and pain in the anal region.
5. Nutritional Problems Are More Common in Crohn’s Disease
Because Crohn’s disease frequently affects the small intestine, patients may struggle to absorb nutrients properly. This struggle results in anemia, a vitamin B12 deficiency, low iron levels, and weight loss.
6. Surgery Has Different Outcomes
Ulcerative colitis can be cured by removing the colon. In Crohn’s disease, surgery is used mainly to treat complications, but inflammation can affect another part of the digestive tract.
7. Smoking Affects the Diseases Differently
Smoking worsens Crohn’s disease. It increases the risk of flare-ups, complications, as well as repeat surgeries. However, Ulcerative Colitis does not show the same pattern. Some studies have found lower rates of ulcerative colitis among smokers. Although smoking is never recommended as a treatment because of its serious health risks.
8. Treatment Approaches
Both conditions are treated with anti-inflammatory medications, immunosuppressing drugs, and dietary changes. But in Crohn’s disease, often more aggressive and long-term treatment is required. This is because it can affect the deeper layers of the bowel and multiple parts of the digestive tract.
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Most people who hear the words “robotic surgery” picture something from a science fiction film. A machine operating independently, the surgeon watching from across the room. The reality is considerably less dramatic and considerably more reassuring.
In robotic-assisted surgery, the surgeon is in control throughout the procedure. The robotic system does not make independent decisions. It functions as a precision instrument, translating the surgeon’s movements into actions with a degree of accuracy that is difficult to achieve through conventional techniques alone. A useful parallel is GPS navigation — the driver still steers, still makes every turn, still decides the route. The technology makes the execution more reliable.
What this means for patients, practically, is a procedure designed to do what it needs to do with less disruption to the surrounding tissue. Less disruption means less post-operative pain. Less pain means rehabilitation begins sooner. And sooner rehabilitation means the things patients actually care about — walking without discomfort, climbing stairs, travelling, returning to work — come back faster.
This is why robotic surgery has gained traction in orthopedics in particular. Joint replacement patients are not looking for a technical achievement. They are looking to move again. They want to walk to the kitchen without wincing, attend a family function without sitting out the evening, and pick up their grandchildren. The recovery is the point, and the precision that robotic assistance enables is what makes that recovery more predictable.
There are persistent myths worth addressing directly. That robotic surgery is risky because it relies on machines — it is not, because the surgeon remains in control and the system includes multiple real-time safety checks. That it is only accessible in premium or specialty settings — increasingly, it is not. That the higher upfront cost cannot be justified — for many patients, the shorter hospital stay, lower post-operative pain, and reduced likelihood of complications make the calculus straightforward.
Healthcare is moving toward precision and personalization, and patients are moving with it. The question most people are now asking before surgery is not only whether the procedure will work. It is how quickly and how fully they will get their life back afterward. Robotic-assisted surgery was built to answer that question.
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