How Old Are Your Organs? New Study Links Organ Aging to Disease Risk

Updated Mar 19, 2025 | 05:00 PM IST

SummaryThe blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
How old are your organs?

Credits: Canva

A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

  • Heart
  • Blood vessels
  • Liver
  • Immune system
  • Pancreas
  • Kidneys
  • Lungs
  • Intestines
  • Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

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John Cena Blames 'Eye Mites,' Not Age, For His Blurry Vision

Updated Jul 17, 2026 | 09:00 PM IST

SummaryDemodex mites are tiny, eight-legged organisms that live naturally on human skin, particularly around hair follicles. Measuring just 0.15 to 0.4 millimetres, they are invisible to the naked eye but are present on the skin of almost every adult.
John Cena Blames 'Eye Mites,' Not Age, For His Blurry Vision

Credit: X.com

When John Cena started noticing blurry vision, he assumed it was simply part of getting older. But the worsening eyesight was also accompanied by redness, itchiness and crusting around his eyes.

“I had a lot of redness and itchiness, and every once in a while, waking up with eye crusties and stuff. At the same time, given my age — I'm 49 now — my vision was going a little bit, so I just figured it was par for the course. But because my vision was going, I needed to see if I needed glasses or prescriptions.”

Until then, Cena had delayed getting his eyes checked. He believed that the symptoms were caused by bright lights, excessive screen time or ageing.

However, an eye examination gave him a surprise. Cena learned that his symptoms were caused by Demodex blepharitis, a condition he says he had never heard of.

“Diagnosed with Demodex blepharitis, which I didn't even know existed.”

What Are Demodex Mites?

Also read: Study Decodes Why COVID Survivors Continue To Suffer Vision Problems

Demodex mites are tiny, eight-legged organisms that live naturally on human skin, particularly around hair follicles. Measuring just 0.15 to 0.4 millimeters, they are invisible to the naked eye but are present on the skin of almost every adult.

These microscopic mites feed on sebum (the skin's natural oil) and dead skin cells, helping remove accumulated debris under normal conditions.

How Do Demodex Mites Work?

Demodex mites are most active at night. They emerge from hair follicles after sunset because ultraviolet (UV) light is harmful to them. While people sleep, the mites feed, crawl and reproduce on the skin's surface.

They are also believed to be stimulated by melatonin, the hormone that helps regulate sleep, creating a unique relationship between humans and these naturally occurring organisms.

When Can Demodex Mites Become A Problem?

Although harmless in small numbers, Demodex mites can cause problems if they multiply excessively—a condition known as demodicosis.

According to Dr. Richard Locksley, professor of medicine at the University of California, San Francisco, an overgrowth of Demodex mites can contribute to:

  • Rosacea
  • Blepharitis (eyelid inflammation)
  • Acne-like breakouts
  • Itchy, inflamed skin

Read More: Wegovy More Likely To Cause Rare Blindness Than Ozempic And Other Similar Drugs, Recent Study Finds

People with weakened immune systems are particularly vulnerable because their bodies may be less able to control mite populations. In addition, inadequate sleep may increase oil production, providing more nourishment for the mites.

Should You Be Worried?

For most healthy people, Demodex mites are a normal part of the skin microbiome and are not considered harmful. Problems generally arise only when their numbers increase significantly.

To help reduce the risk of overgrowth:

  • Wash your face every night with a gentle, non-comedogenic cleanser to remove excess oil and debris.
  • Remove eye makeup and false eyelashes before bed, as these can encourage mite buildup.
  • Get adequate sleep, since poor sleep may increase sebum production.
  • Consult a dermatologist if you experience persistent redness, itching or inflammation around the eyes or skin.

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The Golden Hour In Stroke: Why The First 60 Minutes Can Make All The Difference

Updated Jul 17, 2026 | 07:10 AM IST

SummarySudden loss of balance or coordination, sudden vision loss or changes in one or both eyes, face drooping, arm weakness, speech difficulty, and time to call emergency medical services are the key warning signs of a stroke
The Golden Hour In Stroke: Why The First 60 Minutes Can Make All The Difference

Credit: iStock

A stroke can happen suddenly and without warning, making every minute count. The first 60 minutes after the onset of stroke symptoms are crucial because timely medical treatment can help reduce brain damage and improve recovery.

What is a Stroke?

A stroke happens when the blood flow to an area of the brain is cut off due to either the blockage of a blood vessel supplying that area or the bursting of the said blood vessel. Without adequate blood flow, brain cells are deprived of oxygen and nutrients and begin to be damaged within minutes.

What Happens During the Golden Hour?

The first hour after a stroke is focused on rapid assessment and treatment. Once the patient reaches the hospital, doctors evaluate the symptoms, determine when they started, and perform an urgent brain scan, usually a CT scan, to identify the type of stroke.

This step is important because treatment depends on whether the stroke is caused by a blocked artery (ischemic stroke) or bleeding in the brain (hemorrhagic stroke). For eligible patients with an ischemic stroke, clot-dissolving medication or a procedure to remove the clot may be considered.

Although treatment windows may extend beyond the first hour for some patients, reaching the hospital as early as possible offers the greatest chance of saving brain tissue. In most patients, clot-dissolving medication is given within 4.5 hours of symptom onset, while selected patients may be eligible for treatment up to 9 hours. Mechanical clot removal is generally performed within 6 hours, although carefully selected patients may benefit from the procedure up to 24 hours after symptoms begin. However, earlier treatment is associated with better protection of brain tissue and improved outcomes.

Know the Warning Signs

Recognizing stroke symptoms early can help save valuable time. The BEFAST acronym is a simple way to remember the common warning signs:

B – Sudden loss of balance or coordination

E – Sudden vision loss or changes in one or both eyes

F – Face drooping

A – Arm weakness

S – Speech difficulty

T – Time to call emergency medical services

Other symptoms may include sudden loss of vision, dizziness, difficulty walking, numbness on one side of the body, confusion, or a sudden, severe headache.

Why Every Minute Matters

During a stroke, brain cells continue to be damaged as blood flow remains interrupted. Delays in reaching the hospital can limit treatment options and increase the risk of long-term disability. Seeking medical care as early as possible gives doctors the best chance to provide appropriate treatment.

What Should You Do?

If you notice stroke symptoms in yourself or someone else, do not ignore them or wait for them to improve. Call emergency medical services immediately and note the time the symptoms first appeared, as this information helps doctors decide the most suitable treatment.

The golden hour is a critical window during which timely action can significantly improve outcomes. Recognizing the signs of stroke and seeking immediate medical care can make a meaningful difference in recovery.

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What Happens After Wildfires? Long-Term Health Risks To Watch Out For After Exposure

Updated Jul 16, 2026 | 10:00 PM IST

SummaryWildfire smoke can raise the risk of lung disease, heart problems, neurological disorders, certain cancers, as well as pregnancy complications in the long run.
What Happens After Wildfires? Long-Term Health Risks To Watch Out For After Exposure

Credit: AI

Massive wildfires have ravaged several parts of Canada and other regions of the world, filling the air with hazardous smoke. This has triggered health warnings far beyond the fire zones.

While most people experience immediate breathing problems during and after wildfires, experts say that some health effects can persist long after the skies clear.

Why Is Wildfire Smoke Harmful?

Wildfire smoke is composed of harmful gases and microscopic particles known as PM2.5. These tiny particles are small enough to travel into our lungs and enter the bloodstream, where they can trigger inflammation throughout the body.

Unlike typical air pollution, wildfire smoke also contains toxic substances released from burning homes, plastics, furniture, vehicles, electronics, and industrial materials, making prolonged exposure particularly harmful.

Long-Term Health Risks After Wildfire Exposure

Also read: Delhi's Poor AQI, Monsoon Conditions Put Children's Lungs at Risk: Ways to Keep Kids Safe

Lung And Chronic Respiratory Disease

Prolonged exposure to wildfire smoke can have long-term effects on the respiratory system. Possible health effects may include:

  • Persistent cough
  • Poor lung function
  • Worsening asthma symptoms
  • Increased COPD episodes
  • Greater risk to respiratory infections

Children, older adults, and people with existing lung conditions face the highest risk because their lung function is already compromised.

Heart Disease

Also read: Phones, Pollution, AI: What Is Driving Cognitive Decline In Humans?

The tiny particles in wildfire smoke don't just stay confined to the lungs. Once they enter the bloodstream, they can affect the cardiovascular system. In the long run, research says wildfire smoke exposure can lead to:

  • Heart attacks
  • Stroke
  • Irregular heart rhythms
  • Elevated blood pressure
  • Increased inflammation in blood vessels
  • Effects on Brain Health

With frequent incidences of wildfires, scientists are looking into how wildfire smoke affects the brain. Emerging evidence suggests smoke exposure may contribute to:

Headaches

  • Difficulty concentrating
  • Memory problems
  • Cognitive decline
  • Increased inflammation affecting brain function

Mental Health Consequences

Wildfires can affect mental health in more than one way. Besides the stress of evacuation and property loss, smoke exposure itself may contribute to mental health problems directly. One is at the risk of the following mental health issues after exposure:

  • Anxiety
  • Depression
  • Post-traumatic stress disorder (PTSD)
  • Sleep disturbances

Communities repeatedly exposed to wildfire events may experience prolonged psychological distress that could often go undetected.

Possible Cancer Risk

Growing evidence suggests that long-term exposure to wildfire smoke may increase the risk of several cancers. Studies have reported possible associations with lung cancer, breast cancer, colorectal cancer, bladder cancer, and certain blood cancers

Although researchers say more studies are needed to establish a direct cause-and-effect relationship, the findings highlight the importance of limiting repeated smoke exposure.

Also read: How Air Pollution Puts Heart Patients At Risk - What You Can Do About It

Pregnancy And Infant Health

Pregnant women are among the groups considered most vulnerable to wildfire smoke. Research suggests exposure during pregnancy may increase the risk of preterm birth, low birth weight and other pregnancy complications.

Healthcare providers recommend minimizing outdoor exposure whenever air quality deteriorates.

How To Protect Yourself After Wildfire Exposure?

Even after visible smoke disappears, harmful particles may remain in the air. Experts recommend:

  • Monitor local air quality before going outdoors.
  • Stay indoors when pollution levels are high.
  • Use HEPA air purifiers if available.
  • Wear a well-fitted N95 mask if exposure is unavoidable.
  • Keep doors and windows closed when it is smoky outside.
  • Continue taking prescribed medications for asthma or heart disease.
  • Seek medical attention if coughing, chest pain, breathlessness, or other symptoms persist.

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