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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
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A visit to the emergency ward (ER) of a hospital can definitely feel scary, and you want every reason to avoid ending up there as a patient. From broken bones to life-threatening emergencies, it’s a place filled with urgency, uncertainty, and intense emotions. Imagine what doctors and other health workers face every day.
However, while many cases are unavoidable, there are several that can be completely prevented, said doctors, while sharing a few. These include:
However, ignoring symptoms like a persistent stomachache or a nagging cough can allow a condition to worsen over time, eventually leading to an emergency.
“People say, ‘It’s pretty mild. I’m not worried about it,’” Dr. Evelyn Huang, an emergency-room physician with Orlando Health, was quoted as saying to Time.
“Days become weeks, weeks become months, and months can even become years, and by the time they're seeing me, these things have progressed so far that they’re now something dangerous.”
Seeking timely medical advice and not delaying checkups can help prevent complications and avoid unnecessary ER visits, the expert said.
Dr. Cheyenne Falat, assistant medical director of the adult emergency department at University of Maryland Medical Center stated that every time a patient comes ER with a drowning case, he hears the same story.
“I would have been watching them, but I thought the babysitter was watching them. I thought my spouse was watching them. I thought their grandparents were watching them.”
The doctor recommended instead starting swimming lessons as early as possible. She also urged for fences with childproof gates near pools.
People often don’t realize how quickly conditions can turn.
“They think, ‘I won’t be at risk for hypothermia because it's a little warmer during the day,’” said Falat. “Then they sweat,” which can leave their clothing damp and their bodies more vulnerable once temperatures drop.
Heat-related illnesses include mild dehydration to heat exhaustion and, in the most extreme cases, heat stroke, which can be deadly.
Recently, for example, he treated a young woman who came to the ER with neck pain, a hoarse voice, and bruising; she assured Yoo that she had wanted her partner to choke her. “I’m not judging anyone who enjoys this, but it's way more dangerous than people think,” he said.
A harmless party drug -- gamma-hydroxybutyric acid, or GHB -- can also turn life-threatening. It is a clear, odorless substance sometimes called “liquid ecstasy.”
While in small amounts, it can make people feel relaxed or euphoric, but when taken in overdose, it can lead to unconscious and breathing difficulties. “It’s one of the most awful sights,” Yoo said , adding that in severe cases, some patients need to be put on a ventilator to survive.
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In today’s hyper-connected world, access to health information has never been easier. Yet, ironically, the ability to understand and apply that information remains one of the biggest barriers to better health outcomes.
This is where health literacy comes in, not just the ability to read a pamphlet or follow a doctor’s prescription, but the broader skill of accessing, comprehending, and using health information to make informed decisions for oneself, one’s family, and one’s community.
While definitions vary, there is consensus that health literacy is multi-dimensional. It involves confidence, critical thinking, and practical skills, knowing when to seek care, how to evaluate health claims, and how to follow treatment correctly. In essence, health literacy is the foundation of preventive care and treatment adherence, and its absence can be devastating.
The scale of the problem in India is stark: nearly 90 percent of Indians have low health literacy. This gap directly affects patient outcomes, from delayed diagnoses and poor compliance with treatment to preventable complications and higher healthcare costs.
Several factors explain this reality:
Low health literacy doesn’t just harm individuals; it amplifies inequities and strains the entire healthcare ecosystem. It also worsens misinformation, as people turn to social media or word-of-mouth for guidance, often encountering unverified or unsafe advice.
Certain health check ups can help improve the chances of conception. (Photo credit: iStock)
Planning for pregnancy is an important step that requires proper health preparation for both partners. Preconception health screening helps couples understand fertility status and detect any underlying health issues. Doctors recommend that couples undergo certain medical tests before trying to conceive so that any health concerns can be identified and managed early. Here are some of the tests before pregnancy that can help couples identify potential risks early and improve the chances of a healthy pregnancy. Couples should opt for these tests without fail to ensure a smooth pregnancy.
While many people focus on health during pregnancy, preparing for pregnancy is also equally important. By opting for some crucial tests, couples can improve their chances of a smooth pregnancy and reduce the risk of complications.
Dr. Payal Narang, Consultant Obstetrician & Gynaecologist, Motherhood Hospital, Lullanagar, in an interview with Health and Me, listed some of the important health check-ups for men and women that must be considered before pregnancy.
Couples should follow the advice given by the doctor and take these tests for a smooth pregnancy.
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