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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
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Many people assume that if they exercise regularly, eat healthy, and stay active, they are naturally protected from serious illnesses like lung cancer. It is a comforting belief but unfortunately, it is not entirely true. While a healthy lifestyle lowers the risk of many diseases and improves overall well-being, it does not make anyone completely immune to lung cancer.
This misconception often leads to another problem: delayed diagnosis. When someone who has never smoked or is physically fit develops a persistent cough, unusual tiredness, or breathlessness, they may dismiss these symptoms as a lingering cold, seasonal allergies, or simply overexertion after a workout. Family members may do the same, assuming that someone who looks healthy couldn't possibly have a serious lung condition. As a result, valuable time may be lost before medical help is sought.
Some forms of lung cancer, especially adenocarcinoma, develop in the outer parts of the lungs, where they may grow silently for months before causing noticeable symptoms.
Also read: The 'Safer Than Smoking' Myth? Doctors Warn Vaping May Carry Its Own Lung Cancer Risks
One of the challenges is that active individuals often have better lung capacity and stamina, allowing their bodies to compensate for early changes. This can make the warning signs subtler in the beginning.
A persistent cough, breathlessness during activities that once felt easy, unexplained fatigue, chest discomfort, hoarseness of voice, recurrent chest infections, coughing up blood, or unexplained weight loss should never be ignored, especially if these symptoms last for more than two to three weeks.
Also read: Bryan Johnson's New 2.6M Women's Health Project Centers on Girlfriend's Menstrual Blood
The encouraging news is that early detection can make a significant difference. Recognizing persistent symptoms and seeking medical evaluation promptly can lead to earlier diagnosis, when treatment is often more effective. Depending on an individual's symptoms and risk factors, a doctor may recommend investigations such as a chest X-ray or CT scan.
Staying physically active remains one of the best decisions a person can make for their health. Exercise strengthens the heart, improves lung function, and reduces the risk of several chronic diseases.
But fitness should never create a false sense of security. The body has its own way of asking for attention, and listening to those signals no matter how healthy a person feels can sometimes be the most important step toward protecting long-term health.
By Dr. Jayesh Prajapati, Senior Consultant Surgical Oncology, Sterling Hospital, Ahmedabad
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The first 1,000 days, right from pregnancy until a child's second birthday, are a crucial window for growth and brain development. Hence, understand that breastfeeding during this period plays a key role in building lifelong health and immunity for the child. Read on to know more about how breastfeeding tends to shape the child’s health for life.
The first 1,000 days of a child's life, right from conception until the age of two years, is often a critical time for growth and development. During this time, brain development happens rapidly, organs mature, and even the immune system tends to become stronger.
Good nutrition tends to have a huge impact on the child’s physical health, learning ability, and even overall well-being. Breastfeeding helps the baby to get enough nutrition. Breast milk also protects babies from infections and tends to support healthy growth.
Also read: Breastfeeding Moms Are Mixing Formula & Breast Milk-Should You?
Breastfeeding involves a correct balance of proteins, healthy fats, vitamins, minerals, and antibodies that a growing baby needs. Breastfeeding strengthens the baby's immune system. Babies who are breastfed will be able to prevent diarrhoea, ear infections, and respiratory illnesses.
Important nutrients such as DHA and other healthy fats help in the growth of the brain and nervous system, which may improve learning and cognitive development later in life. Did you know? Breastfeeding is important and even helps to reduce the chances of obesity, type 2 diabetes, and certain allergies as children grow older.
It encourages healthy weight gain during infancy and helps develop better eating habits. Breastfeeding is also beneficial for mothers. It helps the uterus return to its normal size after childbirth, reduces bleeding after delivery, and may lower the risk of breast and ovarian cancers. Breastfeeding creates a strong emotional bond with their baby through close skin-to-skin contact.
Also read: Breastfeeding Week: Experts Share How Breastfeeding Helps You and Your Child?
Hence, follow these tips and ensure proper breastfeeding for the child.
By Dr Nishant Bansal, Consultant - Paediatrician & Neonatologist, Motherhood Hospitals, Noida
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Patient should not be afraid to ask what type of lung cancer, Stage and spread of disease whether it has spread and what is stage of disease, This information helps direct treatment decisions and provides insight into the future prospective of disease status .
The patient should self designate a Trustee who will take care of her Medical Records , fixing up appointment and be responsible for medication administration. A diagnosis of lung cancer can be shocking and worrisome, but knowing what to expect can help patients make more informed choices.
The first lesson is that lung cancer can be very different from patient to patient. Treatment depends on the type, stage as well as genetic changes and health.
For lung cancer patients some patients will require testing the tumour for specific Molecular markers which help in deciding type of immunotherapy . Before beginning treatment, patients should be asked for if they have had the appropriate tests done for fitness before therapy.
Modern lung cancer care may involve surgery, radiation therapy, chemotherapy, targeted medicines and immunotherapy, often in various combinations. The best treatment will depend on the type of cancer and the health of the patient.
Also read: What Is Driving India's High Burden Of Childhood Cancers?
Patients should not quietly accept worsening shortness of breath, pain, fever, severe weakness, poor appetite or side effects of treatment. Early communication can assist doctors in managing complications and maintaining quality of life.
Palliative or supportive care is not just for the end of the cancer course. It can be given along with cancer treatment to help manage symptoms, improve emotional wellbeing and increase everyday comfort.
Above all, I do not think that a diagnosis means there are no options. The treatment of lung cancer is changing rapidly and the results can vary greatly from patient to patient. Ask questions, clarify, and understand treatment plan and when appropriate, get a second opinion before making major decisions.
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