How Old Are Your Organs? New Study Links Organ Aging to Disease Risk

Updated Mar 19, 2025 | 05:00 PM IST

SummaryThe blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
How old are your organs?

Credits: Canva

A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.

The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.

What Organs Were Studied?

The study measured the biological age of nine key organs, including:

  • Heart
  • Blood vessels
  • Liver
  • Immune system
  • Pancreas
  • Kidneys
  • Lungs
  • Intestines
  • Brain

The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.

Organ Aging And Disease Risk

Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.

For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.

One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.

What Is Organ Specific Blood Tests?

The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.

The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."

The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.

End of Article

Can Egg Freezing Reduce Your Egg Quantity? Doctor Explains

Updated Nov 23, 2025 | 10:00 PM IST

SummaryEgg freezing allows women to preserve fertility by retrieving and vitrifying eggs for future use. This guide explains the process, success factors, AMH testing, common misconceptions, costs, and expert advice for choosing the right clinic. It offers clear, practical information for anyone considering egg preservation in India.
egg freezing egg quantity

Credits: Canva

Recent data from the Human Fertilisation and Embryology Authority show a sharp rise in the number of women opting for egg-freezing. Yet the subject remains clouded by many misunderstandings. The decision itself is not simple. It involves emotional questions, significant costs and the physical demands of treatment. One common misunderstanding is the belief that egg freezing can harm egg quality, when the procedure does not lower the inherent quality of the eggs you already have.

We got in touch with Dr Shaweez Faizi, Fertility Specialist, Nova IVF Fertility, Mangalore, who told us more about the same.

What Is Egg Freezing?

Egg freezing, also called oocyte cryopreservation, is a fertility option in which a woman’s eggs are collected, frozen, and kept for future use. The steps include taking hormones to help the ovaries produce multiple mature eggs, retrieving those eggs through a short clinical procedure, and freezing them through a rapid cooling method known as vitrification.

As per Healthline, the frozen eggs are then stored in liquid nitrogen. When pregnancy is planned later, the eggs are thawed, fertilized in a laboratory, and the embryo is transferred to the uterus.

How Egg-Freezing Works?

The journey begins with roughly 8 to 12 days of hormonal tablets and injections that help several follicles grow at once. Dr Shaweez Faizi told us that doctors then use an ultrasound-guided needle to retrieve the mature eggs under light anaesthesia. The eggs are preserved through vitrification. The medication does not pull eggs from future years. It acts only on that month’s cohort, which is why medical bodies consider the procedure safe and ethically sound.

Can Egg Freezing Lower Your Egg Quantity?

Dr Shaweez Faizi told us that egg-freezing does not drain your ovarian reserve for life. The process collects only the group of eggs that your body was already preparing to release in that month. Some women notice a short-term dip in AMH after the procedure, but this usually settles with time. The stored supply inside the ovaries remains unchanged.

For those unversed, AMH, or Anti-Müllerian Hormone, is commonly used to assess ovarian reserve, meaning the approximate number of eggs still present in a woman’s ovaries.

Anti-Müllerian Hormone and Reserve

AMH is often treated as a marker of ovarian reserve, though it naturally varies. Studies show that a small number of women experience a temporary fall in AMH after stimulation, followed by a return to baseline. Specialists usually advise repeating the AMH test a few months after retrieval to get an accurate picture.

Egg Freezing Success Rates

Age at the time of freezing and the number of eggs stored have the strongest influence on outcomes. Global data suggest that women under 38 who freeze about 20 eggs tend to have higher chances of a future live birth. Older women usually retrieve fewer eggs per cycle, and success rates decline. Indian clinics report a wide range of live-birth outcomes, depending on age and the number of usable eggs.

People with low AMH or diminished reserve will have fewer eggs from the start. The issue lies in the baseline biology, not in the freezing itself. Those who have had ovarian surgery, such as endometrioma removal, may have reduced reserve due to the operation and should plan their timing carefully.

Women facing chemotherapy or serious medical treatment should consult both oncologists and fertility specialists. The Indian Fertility Society recently issued guidance on handling low ovarian response and preservation choices.

Practical Steps For Those Considering Egg Freezing

Dr Shaweez Faizi shared a few practical steps for women considering egg freezing:

• Start with basic tests such as AMH, AFC and a hormonal panel.

• Ask detailed questions about expected egg yield for your age, the number of cycles you may need, and the clinic’s real success figures. Advertising often paints a brighter picture than the data.

• Plan financially for medication, scans, retrieval, freezing and long-term storage.

• Keep age in mind, as younger eggs are more likely to develop into healthy embryos.

• Choose established centres that follow national and international practice standards.

Egg-freezing is a recognised and safe method to preserve fertility options, but it is not a guaranteed path to pregnancy.

Costs, success rates and the number of cycles needed vary widely. As the service becomes more accessible in India’s metropolitan centres, careful counselling and realistic planning remain essential before you decide.

End of Article

Azithromycin Warning: Popular Medicine Linked To A Surge in Antibiotic Resistance, Warns Ortho Surgeon

Updated Nov 23, 2025 | 10:14 AM IST

SummaryAzithromycin, one of India’s most commonly used antibiotics, is now at the center of a growing medical concern. Experts warn that frequent, unsupervised use may be weakening its power against dangerous infections. This article explains the rising resistance problem and why doctors are urging careful, guided use of the drug.
azithromycin medicine antibacterial resistance

Credits: Canva

India’s growing dependence on quick, over-the-counter remedies has drawn fresh concern from a senior orthopaedic and sports surgeon in New Delhi. In a recent Instagram video, Dr Obaidur Rahman of Dr Ram Manohar Lohia Hospital warned that the country’s casual use of a common antibiotic is undermining its effectiveness and pushing India closer to a major public health challenge. His message, shared through a post and video, called attention to an urgent issue that often goes unnoticed in everyday medical choices.

What Is Azithromycin?

Azithromycin, sold under brand names such as Zithromax, Azee and Zmax, is a macrolide antibiotic prescribed for various bacterial infections. It works by slowing the growth of harmful bacteria. It does not help with viral illnesses like the common cold or flu, according to MedlinePlus.

Azithromycin Is Being Used “More Than Toffee or Roti”

Dr Rahman explained that one particular antibiotic has become so familiar in Indian homes that many people take it without a second thought. He noted that families frequently reach for this medicine to treat colds, coughs and mild fevers, despite the fact that most of these illnesses are viral. Because antibiotics do not work on viruses, this habit has increased unnecessary exposure and created ideal conditions for resistance to form.

In his post, he described the extent of the overuse by saying that the tablet is consumed even more commonly than basic household foods. This pattern, he said, has quietly pushed India into a vulnerable zone.

Azithromycin Antibiotic Resistance: Azithromycin Losing Power Against Key Bacteria

The antibiotic at the center of his warning is Azithromycin, a drug often prescribed for sore throats and upper respiratory tract infections. Dr Rahman noted that it was once effective against Mycoplasma Pneumonia, a bacterium responsible for pneumonia in adults and children.

He pointed out that this is no longer the case. According to him, India now shows an alarming 80 to 90 percent resistance to Azithromycin when treating infections caused by this bacterium. A medicine that once addressed a wide range of respiratory problems is no longer reliable for many patients.

Azithromycin: Antibiotic Resistance Already Reaching Clinics

Dr Rahman said that antibiotic resistance is not an abstract idea but something he encounters in his orthopaedic practice. He has seen cases where routine antibiotics fail entirely, leaving patients with few options. When commonly used drugs stop working, he added, treatment becomes more complicated, more expensive, and sometimes impossible.

His concern is that if such misuse continues unchecked, India could face a situation where even simple infections become difficult to manage.

The surgeon urged people to avoid taking antibiotics without proper medical advice. Most seasonal respiratory infections resolve on their own, and unnecessary drugs only add to the resistance problem. He encouraged viewers to share the information, especially with those who often purchase antibiotics over the counter.

Azithromycin Warning: Why This Warning Matters Now

Dr Rahman, who works at PGIMER and RML Hospital and specialises in bone, joint and sports injury care, said his experience treating a large volume of patients has made the issue impossible to ignore. He believes that without immediate changes in how antibiotics are used, India risks losing access to medicines that save lives in emergencies.

His message acts as a reminder that antibiotic resistance does not appear suddenly. It builds slowly through small, routine choices. And, as he warns, the cost of ignoring these early signs may be far greater than most people realise.

End of Article

Rebuilding Your Brain Health: 5 Steps You Should Take According To Doctor

Updated Nov 23, 2025 | 06:00 AM IST

SummaryHow well your brain functions as you age depends on how well you took care of it. While we may not realize it, a lot of the things we do, like our sleep schedule, diet and exercise levels, affect our brain health. If you are looking to work on your brain health, here are 5 steps you should follow.
Rebuilding Your Brain Health: 5 Steps You Should Take According To Doctor

(Credit - Canva)

In a recent video, a neurosurgeon listed things he would start doing if he had to work on his brain health, ‘rebuilding it’, from scratch. Many people are focusing on health and bringing about a change in their life so that their health doesn’t suffer. If you wish to do the same but do not know where to start from, Dr Jay Jagannathan, MD, from Jay Jagannathan, MD, explains five easy steps with which you can start.

Your brain health is affected by many things around you, your habits, your diet, who you spend your time with etc. In the video Dr Jaggannath listed 5 things he would start doing if he had to start working on his brain health from the beginning.

In the caption he explained, “After years in neurosurgery, I’ve learned this: Your brain doesn’t need perfection — it needs consistency, balance, and protection. And the biggest changes often come from the simplest habits.”

5 Ways To Rebuild Your Brain Health

five key steps they would take to completely reset and improve their brain health. These strategies focus on combining strict discipline with intentional rest and mindful activities, recognizing the direct connection between physical habits and mental performance.

Sleep Schedule Discipline

The first and most critical step is maintaining strict sleep schedule discipline. This means committing to getting at least six to eight hours of quality sleep every single night without fail. If the individual has a very early start to their day, they must prioritize going to bed much earlier to ensure they meet this crucial rest quota. Prioritizing consistent sleep is essential for the brain to consolidate memories and perform necessary repairs.

Prioritize Strength Training

The second action involves incorporating regular, low-grade resistance (strength) training into the weekly routine. This exercise is especially important for people who spend long hours on their feet, like surgeons. Committing to low-grade resistance training for at least two to three days per week is considered extremely vital because physical strength and exercise directly support better circulation and overall body health, which feeds directly into improved brain function.

Embrace Regular Meditation and Mind-Body Connection

The neurosurgeon stressed the importance of dedicated time for regular meditation. They pointed out that a strong mind-body interface is crucial for endurance and clarity, particularly in demanding fields like surgery. Therefore, engaging in mindful practices such as yoga or meditation is necessary to establish and maintain that vital connection, allowing the brain and body to work together harmoniously and manage high stress levels.

Avoiding Burnout Cycles

The fourth piece of advice is to actively and consciously avoid burnout cycles. Burnout is a dangerous state of chronic stress that can severely damage both the brain's structure and its ability to function effectively. This strategy requires setting firm boundaries and intentionally managing one's workload and stress levels to prevent ever reaching a point of complete mental and physical exhaustion.

Skip the "Hero" Lifestyle

Finally, the fifth point is to firmly reject the "hero lifestyle" of skipping rest. This is the common, misguided habit of trying to power through intense work periods by constantly sacrificing necessary sleep and rest days. The neurosurgeon advises against this trend, asserting that continuous rest and consistent recovery are not optional but are absolutely non-negotiable for achieving and maintaining sustained high performance and long-term brain health.

End of Article