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A new study published in The Lancet Digital Health suggests that biological age of different organs could predict a person's risk of diseases such as cancer, dementia, and heart disease than their actual chronological age. The research analyzed long-term data from Whitehall II study, which had been followed by over 10,000 British adults for more than 35 years.
The blood plasma samples were collected between 1997 and 1999 from participants between ages 45 to 69. Researchers have now examined a follow up data from 6,235 participants, who were by then aged 65 to 89. This was done to see how aging of specific organ may correlate with the development of diseases over two decades.
The study measured the biological age of nine key organs, including:
The researchers were able to find that different organs aged at different rates in different people. In many of the cases multiple organs showed signs of faster aging within the same individual. What is important to note is that those with accelerated aging in certain organs had a higher risk of developing 30 out of the 40 age-related diseases the study had tracked.
Some organ-disease connections were expected—people with rapidly aging lungs were more likely to develop respiratory diseases, and those with aging kidneys had an increased risk of kidney-related conditions. However, the study also found less obvious associations.
For example, individuals with fast-aging kidneys were more prone to diseases in other organs, such as the liver and pancreas. Additionally, multiple fast-aging organs were linked to an increased risk of kidney disease.
One of the most surprising findings was that dementia risk was not best predicted by an aging brain but rather by the immune system’s biological age. This suggests that factors such as chronic inflammation and immune health may play a critical role in neurodegenerative diseases.
The study also highlights the important of the potential of developing blood tests that could assess the biological age of specific organs. Unlike previous complex methods that measured the organ health, this new approach could make things simple to detect early signs of disease.
The leader author of the study Mika Kivimaki, who is also a professor at the University College London's Faculty of Brain sciences pointed out that such tests could be helpful when it comes to guiding personalized healthcare. In a news release, Kivimaki said, "They could advise whether a person needs to take better care of a particular organ and potentially provide an early warning signal that they may be at risk of a particular disease."
The study reinforces the idea that aging does not affect all organs equally and that looking beyond chronological age could offer better insights into disease prevention. By understanding which organs are aging more rapidly, medical professionals may be able to recommend targeted interventions for individuals at higher risk of specific conditions. Future advancements in organ-specific blood testing could revolutionize how we detect and manage age-related diseases, potentially leading to more personalized healthcare strategies.
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For many women, the last day of treatment feels like crossing a finish line they have been running toward for months. There is relief, there is gratitude, and there is often a quiet sense of disbelief that it is actually behind them. But finishing treatment is not really the end of the journey. It is the start of a new chapter—one we call survivorship—and it deserves just as much care and attention as everything that came before. Understanding what lies ahead can make all the difference between living in fear and living well.
Recovery does not mean walking away from the hospital. In the first few years after treatment, survivors are usually asked to return for follow-ups. The reason behind this is simple: if cancer ever returns, catching it early gives the best chance of treating it successfully. Or in many cases it a good habit to keep a check and boost confidence to the survivors.
What often surprises many women is that the impact of cancer treatment may continue even after active treatment ends. Recovery is a gradual process, and experiences can vary significantly from one individual to another depending on the type of cancer, treatment approach, and overall health. In terms of breast cancer, some women may continue to face physical, emotional, or lifestyle-related challenges during survivorship, while others may require ongoing therapies or follow-up care to reduce the risk of recurrence. What must always be remembered is that these issues cannot be addressed in silence. Open communication between the woman and her treatment team may allow problems to be sorted out in time, with the proper support being provided.
Healing is not only physical. Many survivors carry a constant worry about whether the cancer will come back, while others feel strangely lost once the busy routine of treatment falls away. These emotions are completely natural and nothing to be ashamed of. Speaking to a counsellor, joining a support group, or simply being honest with the care team can lighten the burden enormously.
The choices made every day genuinely shape long-term health. Eating plenty of vegetables, fruits, and whole grains, and staying active with something as simple as a thirty-minute walk most days, makes a real difference. Keeping to a healthy weight is especially important, because carrying excess weight is linked to a higher chance of the cancer returningi. Cutting back on alcohol and staying away from tobacco add further protection.
The body changes after cancer and coming to terms with this takes time. Worries about appearance and intimacy are entirely understandable, and they are worth raising during clinic visits, because often there are practical ways to help.
No one understands a patient's body better than the patient herself, which is why every survivor should feel empowered to ask questions. Before treatment ends, it is wise to request a survivorship care plan. This is a summary of the treatment received, together with a clear schedule for future check-ups. Such a document becomes an invaluable guide, both for the survivor and for any doctor she may see in the years ahead.
Survivorship is rarely a straight line. There will be good days and harder ones, moments of confidence and moments of doubt. With regular check-ups, a few sensible habits, and the support of people who care, life after breast cancer can be every bit as rich and full as before—sometimes even more so. Because in the end, the goal of cancer treatment was never just to help women survive. It was always to help them truly live.
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More than 57 million people worldwide are living with dementia, a number expected to triple to over 152 million by 2050. While there is still no cure, growing evidence suggests that healthy lifestyle changes can help improve brain health and preserve cognitive function in older adults at risk of dementia.
A major study published in The Lancet suggests that adopting healthy lifestyle habits can significantly improve memory and thinking skills in older adults at risk of dementia.
The study found that a culturally adapted, structured lifestyle program delivered across 11 Latin American countries produced meaningful improvements in cognitive function over two years. Participants in the intensive program showed 55 per cent greater improvement in overall cognition than those who received general health advice.
Lead author Lucia Crivelli, principal investigator at Fleni, a neurological institute in Buenos Aires, Argentina, said culturally adapted lifestyle interventions can be successfully implemented across diverse communities and "deliver cognitive benefits" for people at risk of dementia.
"Addressing multiple lifestyle factors can positively impact brain health and may eventually be combined with emerging drug therapies to reduce cognitive decline and dementia risk," added Heather M. Snyder, senior vice president of medical and scientific relations at the Alzheimer's Association.
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The clinical trial enrolled 1,065 adults aged 60 to 77 years at increased risk of cognitive decline across 12 sites in Argentina, Bolivia, Brazil, Chile, Colombia, Costa Rica, the Dominican Republic, Ecuador, Mexico, Peru and Uruguay.
Participants were randomly assigned to one of two groups. The Systematic Lifestyle Intervention (SLI) group received ongoing coaching, supervised exercise, personalized nutrition counselling, cognitive training and regular monitoring of cardiovascular risk factors. The Flexible Lifestyle Intervention (FLI) group received general lifestyle recommendations through periodic health education sessions without continuous coaching or supervision.
The structured program combined supervised exercise, a brain-healthy MIND diet, computer-based cognitive training, regular monitoring of blood pressure, blood sugar and weight, and social engagement activities designed to encourage accountability and interaction.
To improve participation, the intervention was adapted to local cultures. Exercise sessions incorporated familiar activities such as salsa and tango, while nutrition counselling focused on regionally available foods including avocado, quinoa, açaí, chia seeds, pumpkin seeds and aguaymanto.
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After two years, participants in the structured intervention experienced:
The cognitive benefits were consistent regardless of participants' age, education level, ethnicity or genetic risk for Alzheimer's disease.
The authors noted that while the program improved performance on cognitive tests, it did not determine whether the intervention prevents dementia. They said longer-term follow-up is needed to establish whether these cognitive improvements ultimately reduce the risk of developing the disease.
Dementia is an umbrella term used to describe a significant decline in mental function that is serious enough to affect everyday life. It commonly impacts memory, thinking, and reasoning skills. Dementia itself is not a single disease but a collection of symptoms caused by underlying conditions such as Alzheimer’s disease or vascular dementia.
Common signs include
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Nearly one in five women aged 50 and older in the United States has osteoporosis, a bone disease that weakens bones and increases the risk of fractures. Yet many women remain undiagnosed because the condition often develops without noticeable symptoms in its early stages.
To improve early detection, the updated recommendations from the US Preventive Services Task Force (USPSTF) advise routine osteoporosis screening for women aged 65 years and older.
The task force also recommends that postmenopausal women younger than 65 undergo a risk assessment to determine whether they should receive a bone density scan.
The USPSTF recommends:
Women under 65 may need screening if they have one or more risk factors, including:
"Screening is important because osteoporosis causes bones to become weaker and fracture more easily, leading to disability, chronic pain, loss of independence, and even death,” said Task Force member Dr. Esa Davis, professor of family and community medicine at the University of Maryland, Baltimore, NBC reported.
Osteoporosis is often called a "silent disease" because it usually causes no symptoms until a bone breaks. Many people only discover they have osteoporosis after experiencing a fracture. The most common fracture sites include the:
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According to the US Centers for Disease Control and Prevention (CDC), data from 2017-2018, published in 2021, showed that:
The study also found that osteopenia—a condition of lower-than-normal bone density that often precedes osteoporosis—was more common in women than men. While osteopenia affected 51.5 per cent of women, it affected 33.5 per cent of men.
In women, osteoporosis is commonly linked to the hormonal changes that occur after menopause.
Estrogen plays an essential role in building and maintaining strong bones. After menopause, estrogen levels decline significantly, accelerating bone loss and increasing the risk of osteoporosis.
People who do not build strong bones during childhood and early adulthood are also at greater risk later in life. Factors such as lack of physical activity, eating disorders, and certain health conditions can prevent the body from achieving optimal bone mass during the younger years.
Doctors use imaging tests to measure bone density and diagnose osteoporosis. A DXA (dual-energy X-ray absorptiometry) scan is the standard diagnostic test and measures bone density in the spine, hip, and wrist using a very small amount of radiation.
Ultrasound can also assess bone quality, but it is not used alone to diagnose osteoporosis. If ultrasound findings suggest bone loss, a DXA scan is still required to confirm the diagnosis.
There is currently no cure for osteoporosis, but treatment and lifestyle changes can help slow bone loss and reduce the risk of fractures.
Experts recommend:
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