Oxytocin, commonly referred to as the "love hormone" because it is involved in bonding and social behavior, is now being investigated for its surprise effect on pregnancy. Although oxytocin is traditionally linked to childbirth, milk letdown during lactation, and emotional bonding, recent findings indicate that this hormone can possibly delay early pregnancy. A study on mice conducted recently has helped explain how the hormone can stop embryonic growth, which may provide new understanding of human fertility and pregnancy.
In a few mammals, such as marsupials, bats, and more than 130 others, a process called "diapause" takes place. This is a natural biological phenomenon that sees embryos suspend their development in order to wait until the right conditions prevail for pregnancy to resume. Although very uncommon and hard to monitor in human beings, clinical experience from in vitro fertilization clinics indicates that human embryos might at times show delayed implantation. One highly documented case in 1996 showed that an embryo implanted in a uterus was in a suspended state for five weeks before implantation took place.
The new research by scientists at the NYU Grossman School of Medicine investigated oxytocin's possible role in inducing this pause in pregnancy. Their results indicate that oxytocin could be a major player in controlling diapause in mice, and they raise questions about its possible role in human pregnancies.
To study the impact of oxytocin on pregnancy, scientists tested female mice who had recently given birth by letting them be mated while still lactating. The research revealed that nursing females had pregnancies that lasted about a week longer than those of the non-nursing mice. Since the normal pregnancy in mice takes only 19 to 21 days, this postponement is a drastic halt to embryonic development.
The research team then sought to determine how this pause occurred. Using optogenetics, a technique that enables the activation of specific neurons through light stimulation, they artificially triggered the release of oxytocin in pregnant mice. After five days of oxytocin stimulation, the researchers examined the mice’s uteruses and found that five out of six had embryos in a dormant state, indicative of diapause. Conversely, pregnant mice that were not administered oxytocin stimulation did not exhibit any indication of developmental arrest.
In further confirmation of their research findings, the scientists administered oxytocin to early-stage mouse embryos in the laboratory setting. They detected identical cellular alteration related to diapause, implying that oxytocin has a direct influence on suspended embryonic development.
The research showed that oxytocin slows down the process through which embryonic cells convert genetic information into proteins. This process, essential for growth and development of the cell, is copying DNA instructions into RNA, which then guides protein synthesis. By suppressing this process, oxytocin puts the embryo into suspended animation.
Interestingly, scientists also learned that embryos without oxytocin receptors were still able to enter diapause, suggesting that more than one biological pathway is used to trigger the pause. Still, having working oxytocin receptors seemed to increase the embryo's chances of surviving the halted state. When oxytocin receptors in the embryos were deactivated, survival rates while in diapause fell to 11% from 42%.
Although this research is in its infancy, it presents exciting possibilities for human fertility studies. A better grasp of the role oxytocin plays during early pregnancy may lead to significant advances in treating unexplained infertility and recurrent miscarriage. If human embryos can enter a state of diapause, further study could reveal how hormonal or environmental influences are responsible for early pregnancy loss.
Also, these discoveries may have greater implications outside pregnancy. As oxytocin is implicated in cell survival, researchers now want to know if what it does in diapause can help understand how to keep nerve cells from dying in the developing nervous system. What stops cells from dying early on might help neurobiology and regenerative medicine advance.
Even with these thrilling findings, much remains to be answered. How long can diapause be in various species, including humans? What are other biochemical signals that cooperate with oxytocin to control embryonic development? And might this information one day lead to targeted fertility treatments or interventions?
More studies are needed to uncover these secrets. As researchers learn more about the multifaceted functions of oxytocin, its image as just the "love hormone" is changing. This potent molecule seems to play a much more intricate function in reproductive biology than has been known, and it may play a role not only in when life starts, but in when it temporarily gets suspended.
Oxytocin's role in pregnancy is turning out to be more complex than originally thought. Though still a primary force behind labor and maternal attachment, it has also recently been found to retard embryonic development, which could have far-reaching consequences for reproductive science. As more research unfolds, the hormone could provide new insights into fertility, enhance IVF success, and even prevent early miscarriage. The possibility of oxytocin-based fertility therapies is an exciting one, and future research will be important to determine how this information can be translated to human pregnancy.
People who work out daily and maintain a healthy diet are deemed invincible and the epitome of discipline, strength, and self-consciousness but for Dilan Patel, a 25-year-old U.K.-based fitness coach, started waking up in the middle of the night sweating profusely night after night, he attributed it to an overheated room or the result of high-intensity workouts. For almost two years, he ignored the warning signs until his body could no longer be ignored. What was initially a nagging irritation was diagnosed as Stage 4B Hodgkin lymphoma, an uncommon blood cancer.
Patel was 23 and like most young adults, establishing his career, pumping iron at the gym, and planning his future. Life was structured and good. But an odd trend persisted that he could not dispel.
"I'd wake up two or three times during the night, totally soaked. My clothes, my bed sheets—everything was wet," he said in a viral Instagram reel for its brutal honesty. "I thought I was just overheating from sleeping under too many blankets. I didn't think anything of it."
But it wasn't just night sweats. He had constant itchiness, which he ignored as dry skin, and visible lumps on his neck, which he explained away as muscle growth from weightlifting. "Everything had an explanation—or so I thought," he remembered.
Gradually, the symptoms worsened. The fatigue became unstoppable, and the night sweats intolerable. Patel consulted medical advice only then. What ensued was a diagnosis that would make his world spin around: Hodgkin lymphoma, an uncommon form of cancer that impacts the lymphatic system.
By the time it was detected, the disease had advanced to Stage 4B. Imaging revealed five tumors—one of which had already spread to his lung. The news was devastating.
“I couldn’t believe it,” he said. “I’d spent two years brushing off the warning signs. My body had been screaming at me.”
Hodgkin lymphoma is a type of blood cancer that starts in the lymphocytes, a form of white blood cell essential to the immune system of the body. It most commonly occurs in the lymph nodes but, as happened in Patel's situation, if not diagnosed promptly, can infect the lungs, liver, or bone marrow.
While uncommon—only around 2,200 new cases are diagnosed annually in the U.K., and less than 0.5% of all cancers—it's one of the more curable cancers if caught in time. Cancer Research UK says that approximately 75% of patients who are diagnosed with Hodgkin lymphoma are still alive ten years later.
In spite of its treatability, the disease is virulent and has the potential to severely compromise quality of life. Survivors have a higher risk of secondary cancers, cardiovascular disease, and respiratory complications from treatment.
One of the biggest problems with Hodgkin lymphoma is that its symptomatology is misleading. The disease may have vague signs that resemble less severe illnesses:
In Patel's situation, all these symptoms existed, but every one of them had an "everyday" cause that delayed his diagnosis. This is common, particularly for young adults, who usually equate these signs with stress, exercise, or changing seasons.
Although the exact cause of Hodgkin lymphoma is still unclear, Epstein-Barr virus (EBV), the same virus that causes mononucleosis, is believed to play a role in the development of approximately two out of five cases. Genetics, a weakened immune system, and environmental exposures are also being researched as possible risks.
Interestingly, although there has been an increase of 38% in rates since the 1990s, adults aged over 70 have registered the steepest rise. But there's also been an increase of 21% amongst younger adults, especially those in the 20-40 group to which Patel belongs.
Fitness professionals are usually the epitome of health. But that self-image can postpone diagnosis, as it did for Patel. Lumps are attributed to muscle gain. Fatigue is considered a normal effect of intense training. Itching and night sweats are attributed to diet or dehydration.
This is a cautionary tale, particularly for young adults who may think that they're too healthy to get sick. Hodgkin lymphoma doesn't care about lifestyle or dietary habits. Even people who look the healthiest can be quietly fighting a serious disease.
Hodgkin lymphoma is routinely treated with chemotherapy, and in certain instances, radiation. As good as the prognosis is, however, early detection remains the best weapon against the disease and reducing long-term side effects.
Even with his advanced diagnosis, however, Patel's tale is also one of determination and vigilance. He's sharing his message from his platform- Don't ignore what your body is trying to tell you.
“If there's one thing I’ve learned from this experience,” he said, “it’s to pay attention to your body. Those little signs? They’re there for a reason. Don’t wait until it’s too late.”
(Credit-Canva)
Home health is an important aspect of healthy living, right alongside healthy eating, and fitness etc. You may have hidden illnesses lurking around the corners of your home, these may seem harmless, but their effect is immediate and intense at times. One such danger that your home may be carrying is black mold. Black mold is a type of fungus that can trigger your immune system. On a milder side, it can cause sneezing, coughing, eye irritation and congestion in your airways. On the other hand, it can worsen asthma symptoms, and black mold allergies cannot be cured, however the symptoms can be treated.
Dealing with mold inside a home is unpleasant, as it can appear in various locations such as walls and ceilings. Black mold is a type of microscopic fungus that has a dark green or black appearance and can have negative consequences for one's health. Autumn Clayman claimed to have experienced several physical symptoms due to black mold after living in an apartment with it. She detailed these experiences in a video shared on TikTok.
Autumn described her first symptom as a burning feeling all over her skin, particularly on her face and neck. She stated that upon entering her apartment, her neck and face would immediately feel like they were burning.
In her TikTok post, she included a picture showing red marks resembling burns on her lower face near her jawline and on her neck. She added that this burning sensation started "immediately" after she entered her apartment and gradually worsened over time.
The Centers of Disease Control and Prevention (CDC) explains that black mold allergy can cause itchiness and redness in eyes and skin
Autumn developed eczema, which initially appeared as a "little speck" on her neck before quickly spreading across her body, including her arms and legs. She noticed small eczema "bumps" all over her body that would then group together into clusters.
In a 2016 study published in Allergy and Asthma Proceedings, researchers aimed to find out the effects of ethnicity and environmental exposure on eczema. They found that factors inside the home, like mold, water damage, or using a humidifier, increased the risk of eczema in non-Hispanic white children even if their parents didn't have allergies.
Autumn also reported feeling more congested than ever before. Although she had previous sinus issues, she stated that she had difficulty breathing most of the time while inside her apartment.
The Cleveland Clinic explains that exposure to black mold can trigger shortness of breath, nasal congestion etc.
The fourth symptom Autumn attributed to black mold exposure was burning, itchy eyes. She claimed that her eyes were constantly irritated.
Autumn shared that despite getting sufficient sleep, she constantly felt exhausted and tired. She also recalled often feeling "depressed" and "drained," but initially thought this was just due to stress.
WebMD explains that exposure to black mold can not only give you joint and muscle pain, headaches, night sweats, as well as the tiredness even after resting.
After getting her apartment completely checked, she concluded that her apartment was the cause of her health problems because she had "never experienced health issues like this before," her stress levels were not unusually high, and she had "never dealt with eczema before."
Mould and dampness are caused by excessive moisture. Therefore, if these issues are present, it is advised to identify the source of the excess moisture in the home to facilitate repairs or take steps to reduce humidity. NHS Inform advises that while a professional may be needed for extensive mold removal, small amounts might be removable by the individual.
Move over white noise—pink noise is the latest trend gaining popularity among people seeking better sleep and deeper relaxation. This softer, more soothing sound is fast becoming a go-to tool, alongside brown and green noise, in what some call a 'rainbow of relaxation.' Each of these coloured sounds is believed to influence sleep, focus, and overall calm—but is there any science to support the claims?
Though the research is still in its early stages, that hasn’t stopped people from spending hours listening to these sounds on YouTube or through meditation apps that now offer curated colour-noise playlists under paid subscriptions.
To understand pink noise, it's helpful to first look at white noise — the most well-known of the group. White noise resembles the static heard on a television or radio and is defined by sound engineers as containing equal volume across all frequencies detectable by the human ear. It gets its name from white light, which contains all visible colour wavelengths.
However, white noise’s high frequencies can be harsh. That’s where pink noise comes in — it reduces the intensity of higher frequencies, producing a softer, lower-pitched sound similar to rain or ocean waves. Brown noise goes even deeper, offering a richer rumble that many find soothing.
While pink, white, and brown noise have clear definitions in audio engineering, other colour noises—like green or blue—are newer and more loosely defined.
Though still limited, there’s some emerging science behind colour noises. A recent review of small studies found that both white and pink noise may offer minor benefits to people with attention-deficit/hyperactivity disorder (ADHD). According to Joel Nigg, an ADHD researcher at Oregon Health & Science University, these noises may stimulate the brain without offering actual information—which helps prevent distraction.
White noise has also been used in tinnitus treatment—helping mask the ringing or buzzing in the ears. Meanwhile, scientists at Northwestern University are exploring how short bursts of pink noise might boost slow-wave brain activity during deep sleep. Preliminary studies suggest that these pink noise pulses could enhance memory and promote relaxation.
Dr. Roneil Malkani, a neurology professor at Northwestern University Feinberg School of Medicine, explains that pink noise closely mirrors the natural frequency distribution of brain waves seen during slow-wave sleep. This similarity could help explain its calming effect. If the research holds up, it may lead to devices that use personalised pink noise to improve memory or sleep quality. However, Dr. Malkani cautions that “there’s still a lot of work we have to do.”
If colour noises feel relaxing or help block distractions, they can be a helpful tool. Just be mindful of volume. “Keep it quiet to avoid hearing damage and give your ears regular breaks,” Nigg advises. As the trend grows, pink noise may prove to be more than just a fad, offering a gentle, non-invasive way to improve rest and well-being.
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