Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.

What Is Gut Microbiome?

Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.

How Does Gut Microbiome Influence Your Health?

The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:

Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.

Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.

Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.

Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.

Gut Microbiome And Weight Management

An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.

Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.

Gut Health And Disease Prevention

The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.

Impact On Heart Health

Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.

Blood Sugar Regulation And Diabetes Risk

The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.

Connection Between Gut And Brain

The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.

Tips For Healthier Gut Microbiome

Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:

• Eat a diverse range of foods: A varied diet rich in fiber, legumes, and fruits promotes microbial diversity.
• Consume fermented foods: Yogurt, kefir, and sauerkraut contain probiotics that enhance gut health.
• Limit artificial sweeteners: Some artificial sweeteners can encourage the growth of harmful bacteria.
• Include prebiotic foods: Bananas, oats, and asparagus contain fibers that nourish beneficial bacteria.
• Breastfeed infants when possible: Breastfeeding promotes a healthier gut microbiome in babies.
• Choose whole grains: Whole grains contain fiber and beneficial compounds that support digestive health.
• Opt for a plant-based diet: Vegetarian diets may reduce inflammation and support a healthier gut microbiome.
• Consume polyphenol-rich foods: Green tea, dark chocolate, and olive oil contain compounds that foster beneficial bacteria.
• Take probiotics if needed: Probiotic supplements can help restore gut balance after disruptions, such as antibiotic use.
• Use antibiotics cautiously: While antibiotics can be life-saving, overuse can harm beneficial gut bacteria.

Living under constant psychosocial stress can significantly raise the risk of developing dementia and a stroke, a JAMA Network study suggests.

Psychosocial stress is a type of stress related to our relationships with others, usually arising from feeling judged, excluded, or not enough in others' eyes. It can also put a person in fight-or-flight mode, causing both mental and physical symptoms.

According to Chinese researchers, people who experience this form of stress in childhood as well as adulthood face more than a threefold higher risk of developing dementia compared with those in other groups.

Similarly, young people experiencing stressful situations in their adulthood had a significantly higher risk of stroke incidence that their counterparts.

Based on these results, the study highlights that early identification of psychosocial stressors, combined with effective mental health support and depression prevention, may reduce the long-term burden of neurodegenerative and cerebrovascular disease.

What Did The Study Find?

The scientists defined adverse childhood experiences (ACEs) as traumatic exposures occurring during childhood, typically grouped into 3 categories: household dysfunction, social dysfunction and family death or disability.

On the other hand, traumatic exposures occurring during adulthood were defined as adverse adult experiences (AAEs), which include events such as the death of a child, lifetime discrimination, ever being confined to bed, ever being hospitalized for a month or longer and ever leaving a job due to health conditions.

While analyzing the data they collected from the participants, the researchers also found that depression partly explained the links in all major relationships as it accounted for more than one-third of the connection between childhood adversity and dementia, and about one-fifth of the link between adulthood adversity and both dementia and stroke.

READ MORE: Avoid Doing These 3 Things Prevent Dementia, According To Neurologist

These findings suggest that long-term psychological stress may lead to brain and blood vessel diseases by causing ongoing emotional distress, unhealthy behaviours, and biological changes like inflammation and abnormal stress responses.

Psychosocial Stress: An Unseen Form Of Stress

Psychosocial stress can trigger physiological responses like increased heart rate, cortisol secretion, and inflammation, significantly increasing risks for hypertension, cardiovascular disease and mental health disorders.

This kind of stress can affect men, women, and people of all genders differently, but many of the symptoms are still the same. Common symptoms include:

• Sweating
• An increase in blood pressure
• Rapid heartbeat
• Dizziness
• Nausea and digestive problems
• Strong emotional reactions such as sadness or irritability
• Drug or alcohol abuse

These symptoms can be acute or chronic, meaning for some people they go away, and for others, they persist over a long period of time. Meeting with a therapist is often recommended for those living with chronic stress.

Experts typically suggest developing coping mechanisms include building support networks, utilizing relaxation techniques, and, in cases of severe mental impact, seeking professional support to help deal with psychosocial stress.

Cardiovascular disease remains the leading cause of death among women, claiming more lives each year than all cancers combined. Yet, it continues to be misunderstood, underdiagnosed, and often dismissed as a “male” health problem. In Ohio and across the US, women are now using a striking visual message to confront this reality head-on, by quite literally dressing for the cause.

February, observed as American Heart Month, marks a renewed push to educate communities about heart disease, especially among women. Health advocates stress that while the spotlight is brightest this month, the risks and responsibilities extend far beyond the calendar.

“It’s our Super Bowl,” said Lauren Thomas, development director for the American Heart Association of North Central West Virginia and Ohio Valley. “It’s about awareness. Heart health is not a one-month conversation. It has to be a year-round priority where people actively put their hearts first.”

Why Red Has Become a Warning Sign

Across Ohio, women are wearing red, a color long associated with love but also with danger. The message is deliberate. Red symbolizes the urgency of cardiovascular disease, a condition responsible for one in every three deaths among women.

“When we wear red, we start conversations that many people avoid,” said Melissa Pratt, a heart disease survivor, reported WBBJ News. “One in three women die from cardiovascular disease. Wearing red encourages women to get checked, understand their risks, and take their health seriously.”

From landmarks lit in red to workplaces, neighborhoods, and social media feeds filled with crimson outfits, the visual campaign is meant to disrupt complacency. It asks a confronting question. If heart disease is killing women at this scale, why is it still not treated like a crisis?

Ohio Valley And Downtown Jackson Women Taking the Lead

Coinciding with American Heart Month, the Ohio Valley Women of Impact campaign launches this Friday. Six local women, Crissy Clutter, Jan Pattishall-Krupinski, Lacy Ferguson, Shelbie Smith, Jennifer Hall-Fawson, and Laurie Conway, are leading fundraising and awareness efforts aimed at improving women’s heart health.

Their work focuses on education, early detection, and supporting research that better understands how heart disease presents differently in women. Symptoms in women can be subtle, ranging from fatigue and nausea to jaw or back pain, which often delays diagnosis and treatment.

Turning Awareness Into Action

To mark the start of the month, the American Heart Association hosted a National Wear Red Day breakfast on Friday morning at the LIFT Wellness Center in Jackson Walk Plaza. The event brought together survivors, advocates, and health professionals to reinforce a simple but powerful message. Awareness must lead to action.

Health experts continue to urge women to prioritize regular checkups, manage blood pressure, cholesterol, and stress, and recognize early warning signs. Lifestyle changes, timely screenings, and informed conversations can significantly reduce risk.

Dressed In Death, Fighting For Life

The women of Ohio are not wearing red for fashion. They are wearing it as a warning, a remembrance, and a call to action. In dressing themselves in the color of urgency, they are confronting a disease that has taken too many lives quietly. This February, their message is clear. Heart disease is not inevitable, but ignoring it can be deadly.

If your roots trace back to the Indian subcontinent, your risk of developing type 2 diabetes is significantly higher than that of Europeans. Research shows that Indians, Pakistanis, and Bangladeshis are up to six times more likely to develop the condition, often at a younger age and at lower body weights. For years, carbohydrate-heavy diets were blamed. But growing scientific evidence points to a far deeper and darker cause: repeated famines during British colonial rule that may have altered metabolic resilience across generations.

Can Hunger Change Human Biology?

The idea that starvation can leave a genetic imprint may sound extreme, but science supports it. Prolonged nutrient deprivation can permanently affect how the body stores fat, processes glucose, and responds to food abundance later in life. Even a single famine can raise the risk of metabolic disorders such as diabetes in future generations.

This understanding forms the basis of the “thrifty genotype hypothesis,” a concept widely discussed in evolutionary biology.

The Thrifty Genotype Hypothesis Explained

The thrifty genotype hypothesis suggests that populations exposed to repeated famines develop genetic traits that help conserve energy. These traits are lifesaving during scarcity but become harmful in times of plenty, increasing the risk of obesity and diabetes.

Economic historian Mike Davis documents that India experienced 31 major famines during 190 years of British rule between 1757 and 1947, roughly one every six years. By contrast, only 17 famines occurred in the previous 2,000 years. Davis estimates that 29 million people died in the Victorian era alone. Economic anthropologist Jason Hickel places the death toll from colonial policies between 1880 and 1920 at around 100 million.

Scientific Evidence Linking Famines to Diabetes

A study published in Frontiers in Public Health titled The Elevated Susceptibility to Diabetes in India: An Evolutionary Perspective argues that these famines reshaped metabolic traits. The researchers note that Indians tend to have a higher fat-to-lean mass ratio, lower average birth weight, and reduced ability to clear glucose. This combination increases metabolic stress and lowers resilience, explaining earlier onset of diabetes compared to Europeans.

A Nation That Shrunk Over Time

Colonial-era famines also affected physical growth. Studies show that average Indian height declined by about 1.8 cm per century during British rule. Historian accounts describe ancient Indians as tall and robust, with even Greek chroniclers noting their stature during Alexander’s invasion. By the 1960s, however, Indians were about 15 cm shorter than their Mesolithic ancestors.

Read: How Colonialism Continues To Bear An Impact On The South Asian Health Crisis

While the British did not cause early declines, widespread impoverishment under colonial rule sharply accelerated the trend. Only in the past 50 years has average height begun to recover.

Famines Were Policy Failures, Not Nature

Mike Davis argues that colonial famines were driven not by food shortages but by policy. Grain continued to be exported even as millions starved. During the 1876 famine, Viceroy Robert Bulwer-Lytton refused to halt exports, and relief work was deliberately discouraged. Davis describes these deaths as the result of state policy, not natural disaster.

Medical journal The Lancet estimated that 19 million Indians died during famines in the 1890s alone.

Breaking the Diabetes Cycle

India now faces the consequences. According to the Indian Council of Medical Research, over 101 million Indians live with diabetes today. Experts argue that prevention must begin early, with reduced sugar intake, low-glycaemic diets, healthier fats, and compulsory physical activity in schools. Education about famine-linked intergenerational health risks could also help younger generations make informed choices.

India has avoided famine since Independence in 1947. The next challenge is ensuring that history’s biological scars do not continue to shape its future.