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Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.
Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.
The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:
Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.
Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.
Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.
Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.
An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.
Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.
The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.
Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.
The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.
The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.
Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:
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The NHS has released fresh guidance on how to manage flu symptoms, setting out four simple steps that could help people recover faster. Influenza, commonly known as flu, is a highly contagious viral illness that affects the respiratory system, including the nose, throat, and lungs. It is marked by a sudden onset of fever, muscle aches, headaches, a persistent dry cough, and extreme tiredness, making it far more serious than the common cold.
Recent data from NHS England shows that in the first week of January, an average of 2,924 hospital beds across England were taken up by patients with flu. This figure reflects a nine per cent increase compared with the previous week.
With flu cases continuing to climb, the NHS has shared several important steps that people can follow to help support a quicker recovery.
In a recent update, NHS England warned that social gatherings during Christmas and New Year may have led to a resurgence of winter illnesses. NHS national medical director Professor Meghana Pandit said: “It is clear that the pressure on the NHS this winter is far from easing, with hospitals once again seeing a rise in patients admitted with flu and other respiratory viruses last week.
“The colder weather is also bringing more vulnerable patients to A&E with breathing difficulties, along with an increase in injuries caused by slips and falls in icy conditions, making this an exceptionally demanding period.”
According to the Mirror, she added: “Staff continue to work extremely hard, with teams across the country doing everything possible to ensure patients receive the care they need. It remains important for people to seek care as usual, and there are still many opportunities to get vaccinated and protect yourself against flu.”
The NHS says flu symptoms tend to appear suddenly and may include:
Children may experience similar symptoms, but they can also have earaches and may appear more tired or less active than usual.
The NHS states: “If you have flu, there are steps you can take to help yourself recover more quickly.”
You should contact NHS 111 or arrange an urgent GP appointment if you or your child have flu symptoms and:
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Cipla, a global name in inhalation therapies, has announced the launch of Afrezza, the world’s only rapid-acting inhaled insulin, in India. The drug is approved for adults with type 1 and type 2 diabetes to help manage high blood sugar levels and represents a notable change in how insulin can be delivered in a country facing a growing diabetes crisis.
For many patients, injecting insulin during long workdays or in public spaces can be uncomfortable or inconvenient. While insulin injections are widely used, awareness around inhaled insulin remains limited. Below, we explain how inhaled insulin works and what it means for people living with diabetes.
Inhaled insulin is a fast-acting form of insulin that is taken as a fine powder through an inhaler. Instead of being injected, it is breathed into the lungs, where it is quickly absorbed into the bloodstream to manage blood sugar spikes that occur after meals. This makes it a needle-free option for adults with type 1 or type 2 diabetes.
It begins working very rapidly, often just before or at the start of a meal, and exits the body sooner than injectable insulin. Because of this, it may lower the risk of insulin stacking and offers greater flexibility around mealtimes. Afrezza is currently the main FDA-approved inhaled insulin available.
The insulin comes as a dry powder and is taken using a small, discreet inhaler with single-use cartridges available in 4, 8, and 12-unit doses. It has been approved by the FDA for adults with type 1 and type 2 diabetes to help control blood sugar rises after meals. “Its absorption into the bloodstream is faster than injectable rapid-acting insulins such as lispro or aspart,” said Dr Hetashvi Gondaliya, as reported by The Indian Express.
Before starting inhaled insulin, patients are required to undergo lung function tests. The insulin itself is identical to the insulin used in injections. What differs is the way it enters the body.
In simple terms, the insulin is not new, only the method of delivery is. Once inhaled, it is absorbed through the lungs, passes into the bloodstream, and helps control the rise in blood sugar levels that happens after eating.
Inhaled insulin is not necessarily better for everyone, but it offers an alternative to injections. It works faster to control post-meal blood sugar levels and may appeal to people who dislike needles. However, it is less efficient than injected insulin, requires a specific inhaler, and is not suitable for all patients.
Studies show that blood sugar control is similar to injectable insulin, but inhaled insulin must still be used along with long-acting basal insulin. It is best viewed as an option rather than a replacement.
According to the National Institutes of Health, inhaled insulin is not appropriate for everyone. It may be considered for adults with type 1 or type 2 diabetes who want a needle-free option or need rapid control of blood sugar after meals.
However, it is not recommended for people who smoke or have smoked in the past six months, or for those with lung conditions such as asthma, COPD, or bronchitis. It is also not approved for children or pregnant women. Lung health and ongoing insulin needs must be carefully evaluated before starting this treatment.
Always consult your doctor before switching to or starting inhaled insulin. Your healthcare provider can help determine whether it is safe and suitable for you based on your medical history and lung health.
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People should be aware of a rare and unpredictable condition called SCAD. Spontaneous coronary artery dissection occurs when the inner layers of a coronary artery split away from the outer wall. When this happens, blood can leak into the space between the layers, leading to clot formation. If these clots grow large enough, they can block blood flow to the heart and cause a heart attack.
Doctors are still struggling to fully understand this condition. The cause remains unknown, and it often strikes suddenly in people who do not have the usual risk factors linked to heart disease. SCAD is most commonly seen in women between the ages of 45 and 53, although it can affect people of any age or gender.
SCAD is an acronym that can refer to different things, but it is most widely used to describe Spontaneous Coronary Artery Dissection. This is a serious heart condition in which a tear forms in one of the arteries supplying blood to the heart, potentially triggering a heart attack. SCAD is also the name of the Savannah College of Art and Design, a well-known creative university in the United States, and an Indian NGO working in the field of social change and development.
According to the British Heart Foundation, SCAD is a condition that “can’t currently be predicted or prevented.” The charity stresses the importance of seeking medical help if symptoms appear, so the condition can be identified as early as possible. Many of the warning signs are similar to those of angina or a heart attack, which can make it difficult to recognise.
The symptoms of SCAD often resemble those associated with angina or a heart attack. These may include:
The British Heart Foundation advises anyone experiencing chest pain or these symptoms to call 999 straight away. One of the dangers of SCAD is that people may dismiss the symptoms, believing they are not at risk of a heart attack. Experts say the condition cannot be predicted or prevented.
Neck pain can sometimes be linked to arterial dissections, which involve a tear in blood vessels supplying vital organs. In such cases, the pain is often sudden, severe, and felt on one side of the neck. It may appear on its own or develop before more serious symptoms, such as those associated with a stroke or heart-related event.
The pain occurs due to damage to the artery wall and should always be treated as a medical emergency. While neck pain is commonly associated with muscle strain, experts warn that, in rare cases, it can signal a much more serious underlying problem.
According to the American Heart Association, neck pain related to arterial dissection may present in the following ways:
Around 80 percent of people diagnosed with SCAD are women, and the condition is known to occur during pregnancy or shortly after childbirth. Because it develops without warning, SCAD is often discovered only after a major medical event, such as a heart attack.
Treatment depends on the severity of the condition. Some patients are managed with medication to reduce the risk of blood clots, while others may require stents to keep the artery open. In rare cases, coronary artery bypass surgery is needed to restore blood flow.
The British Heart Foundation notes that receiving a SCAD diagnosis can be deeply unsettling, especially when it follows an emergency. Many patients report feeling isolated, largely because the condition is so rare and not widely understood.
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