Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.

What Is Gut Microbiome?

Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.

How Does Gut Microbiome Influence Your Health?

The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:

Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.

Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.

Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.

Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.

Gut Microbiome And Weight Management

An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.

Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.

Gut Health And Disease Prevention

The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.

Impact On Heart Health

Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.

Blood Sugar Regulation And Diabetes Risk

The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.

Connection Between Gut And Brain

The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.

Tips For Healthier Gut Microbiome

Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:

• Eat a diverse range of foods: A varied diet rich in fiber, legumes, and fruits promotes microbial diversity.
• Consume fermented foods: Yogurt, kefir, and sauerkraut contain probiotics that enhance gut health.
• Limit artificial sweeteners: Some artificial sweeteners can encourage the growth of harmful bacteria.
• Include prebiotic foods: Bananas, oats, and asparagus contain fibers that nourish beneficial bacteria.
• Breastfeed infants when possible: Breastfeeding promotes a healthier gut microbiome in babies.
• Choose whole grains: Whole grains contain fiber and beneficial compounds that support digestive health.
• Opt for a plant-based diet: Vegetarian diets may reduce inflammation and support a healthier gut microbiome.
• Consume polyphenol-rich foods: Green tea, dark chocolate, and olive oil contain compounds that foster beneficial bacteria.
• Take probiotics if needed: Probiotic supplements can help restore gut balance after disruptions, such as antibiotic use.
• Use antibiotics cautiously: While antibiotics can be life-saving, overuse can harm beneficial gut bacteria.

A new Lancet study titled Burden of MASLD and liver fibrosis: evidence from the Phenome India cohort published in The Lancet Regional Health - South Asia found that nearly four in 10 Indian adults have fatty liver or what scientifically is known as the metabolic dysfunction-associated steatotic liver disease (MASLD), formerly non as NAFLD or non-alcoholic fatty liver disease.

The study also highlights a more worrying condition that a sizeable proportion of the Indian population already show signs of liver fibrosis. This is an early scarring process that could lead to cirrhosis or liver cancer if left unchecked.

Lancet Study: How Was It Conducted?

The study analyzed data from more than 7,700 adults across 27 cities in India. The study found that 38.9 per cent of participants had MASLD. The authors also noted that this figure is similar to the global estimates, however, is deeply concerning for India's population and size of the country, including the ever-rising burden of diabetes and obesity.

The study also found that 6.3 per cent of people who live with MASLD had significant liver fibrosis, as compared to 1.7 per cent of those without fatty liver.

Read: Indians Are At Most Risk Of Having Fatty Liver Disease, According To Doctor

The study also found that 2.4 per cent of the entire population analyzed showed evidence of significant fibrosis. Why is this concerning? Fibrosis is a strong predicator of future complications. With the advancement of scarring, liver failure, cirrhosis, and liver caser risk also rises.

Lancet Study: Who Are At Risk?

The study found that people with obesity, diabetes, and central or abdominal fat were more likely to have MASLD. Obesity also was seen as the strongest risk factor, with likelihood rising steeply from overweight to severe obesity.

Another factor was also age. Liver fibrosis was seen in adults over the age of 60 years and in people with diabetes, among whom nearly one in ten showed fibrotic changes.

The study also showed that there was a presence of "Lean MASLD", which means it could also happen in people who are not overweight and have a normal body mass index. This is often linked to insulin resistance and visceral fat, which is the fat around internal organs. This tend to accumulate abdominal fat even at lower body weights.

Lancet Study: Can MASLD And Other Liver Diseases Be Prevented?

As per the authors of the study, MASLD is highly modifiable, especially at early stages. There are evidence that show that weight loss reduces liver fat and inflammation. Regular physical activity also improves insulin sensitivity, along with balanced diet. The diet must be consumed without or with very low sugar and ultra-processed food, which helps in control of diabetes and cholesterol and slows down disease progression.

Authors also noted that people should get their fatty liver disease scanned regularly. Especially because MASLD is common among people with obesity and diabetes. There are many non-aggressive tools that could also detect fibrosis early.

When Robert F Kennedy Jr took charge of America's health as the Secretary of Health and Human Services in 2025, the promise was sweeping. It included: restoring trust, clean up the food supply, rethink vaccine, though he clearly did state during debates that he is not against it, and reshape a system he said had failed many families for decades.

On February 13, 2025, the day he was sworn in, the US President Trump said, "Our public health system has squandered the trust of our citizens. They don’t trust us. They don’t trust anybody, frankly. They’ve gone through hell.” Trump promised that Kennedy would "lead out campaign of historic reforms and restore faith in American health care". A year from now, Health and Me analyzes those MAHA (Make America Healthy Again) promises.

he Make America Healthy Again (MAHA) movement produced policy changes, lawsuits, agency upheavals and intense public debate, but also falling trust in public health agencies and uncertain long-term impact.

Read: I'm Not Afraid Of Germs, I Snorted Cocaine Off Toilet Seats, Says US Secretary of Health, RFK Jr

The Fight Against Ultra Processed Foods

Kennedy’s campaign had centered on a simple message: American children are sicker because their food is broken. As health secretary, he created a MAHA Commission to investigate children’s health.

Its first report blamed rising chronic illness partly on diet and raised alarms about herbicides like glyphosate and atrazine being found in children and pregnant women. Farmers and food companies revolted, lobbying lawmakers in agricultural states.

The backlash worked. By the commission’s follow-up report in September, pesticide references had vanished entirely, a clear sign of political limits.

Read: Under RFK Jr's MAHA, More Food Dyes Are Getting Banned In US

Still, Kennedy pushed nutrition policy aggressively. New dietary guidelines promoted whole milk, red meat and less ultraprocessed food. Supporters applauded a focus on real food, and food companies even pledged to remove artificial dyes by 2027.

But critics said the results were partial at best. Nutrition expert Dr. Marion Nestle told CNN that despite momentum, progress stalled: “One big disappointment is the lack of progress on removing industrial and agricultural chemicals from the food supply.”

An Anti-vaxxer's Vaccine Policy

No area defined Kennedy’s first year more than vaccines.

He fired members of a CDC advisory panel, replaced them, sometimes with skeptics, and cut the list of routinely recommended childhood vaccines from 17 to 11, aligning the U.S. closer to Denmark’s schedule. Several vaccines, including flu and hepatitis A, were removed from routine recommendations.

Supporters framed it as restoring parental choice. Critics called it dangerous.

Read: RFK Jr. Removes Entire CDC Vaccine Advisory Committee

Yale public health expert Dr. Jason Schwartz told CNN the consequences could be severe: “Today, the federal government’s public health agencies and leaders represent the greatest threat to efforts to prevent measles… a scenario that would have been inconceivable a few years ago.”

Outbreaks soon followed, measles deaths returned after a decade without them. And polling showed trust in the CDC falling from 59% to 47%.

Kennedy argued declining trust started before him and that transparency would fix it. But many scientists disagreed. Infectious disease expert Dr. Michael Osterholm told CNN the new approach replaced evidence with politics: “Decisions are being made based on ideology.”

Health Agencies Saw A Lot Of Hirings, Firings, And Restructuring

Within days of Kennedy’s swearing-in, thousands of employees across CDC, FDA and NIH were fired in a sweeping reorganization aimed at shrinking the department by about 20,000 workers.

Leadership churn followed. A CDC director was ousted, nominees withdrawn, senior officials resigned, and a major shooting at CDC headquarters, carried out by a man angry about vaccines, intensified tensions. Hundreds of staff later urged Kennedy to stop spreading misinformation.

Researchers warned expertise was disappearing. Johns Hopkins epidemiologist Dr. Caitlin Rivers told CNN local health departments depend on federal specialists: "A lot of those people aren’t there anymore.”

Read: How Susan Monarez's Appoint As CDC Director Can Change US Health Sector?

Meanwhile, Kennedy struggled with forces outside his control. According to Politico reporting, his attempts to regulate agricultural chemicals faltered because authority belonged to the Environmental Protection Agency and Republican lawmakers pushed back heavily.

At the Food and Drug Administration, Kennedy’s agenda pulled in two directions.

On one hand, the administration sought cheaper drugs and faster access. On the other, it raised evidence standards and blocked or slowed approvals, including scrutiny of a muscular dystrophy therapy after patient deaths.

Also Read: Top U.S. Medical Associations Ousted from CDC Vaccine Workgroups in Sudden Shake-Up

Even allies noticed contradictions. The agency alternated between right-to-try deregulation and skepticism toward pharmaceutical safety. The result: uncertainty for both industry and patients.

Restoring Faith In Public Health

Trump promised Kennedy would restore faith in public health. Instead, surveys show trust in both health agencies and Kennedy himself fell.

Read: What Is 'Make America Healthy Again' All About?

Nutrition reforms gained modest support. Drug price messaging resonated politically. But experts repeatedly emphasized the same conclusion: vaccine policy overshadowed everything else.

Nutrition policy expert Dr. Jerold Mande told CNN messaging that authorities had lied for decades may have backfired:

“Most people will take from that: we shouldn’t trust anybody."

The World Health Organization (WHO) is urging countries to accelerate efforts to provide proper eye care, as a new Lancet Global Health study shows that nearly half of all people across the world facing cataract‑related blindness still need access to surgery.

As of now, statistical models predict that the global coverage of cataract surgery is set to increase by about 8.4 percent this decade. However, progress needs to accelerate sharply to meet the World Health Assembly target of a 30 percent increase by 2030.

Devora Kestel, Director, WHO Department of Noncommunicable Diseases and Mental Health: "Cataract surgery is one of the most powerful tools we have to restore vision and transform lives. When people regain their sight, they regain independence, dignity, and opportunity."

The literature review, which analyzed reports from 68 country estimates for 2023 and 2024 shows that the African Region faces the greatest gap, with three in four people who need cataract surgery remaining untreated.

Additionally, women are disproportionately affected across all regions, consistently experiencing lower access to care than men.

Researchers noted that the gap in access to surgery was mostly due to long-standing structural barriers, including shortages and unequal distribution of trained eye-care professionals, high out-of-pocket costs, long waiting times and limited awareness or demand for surgery, even where services exist.

In addition, while age is the primary risk factor for cataract, other contributors such as prolonged UV-B exposure, tobacco use, corticosteroid use and diabetes can accelerate its development.

What Is A Cataract?

Most cataracts develop slowly and don't disturb eyesight early on. But with time, cataracts will eventually affect vision. Symptoms of cataracts include:

• Clouded, blurred or dim vision.
• Trouble seeing at night.
• Sensitivity to light and glare.
• Need for brighter light for reading and other activities.
• Seeing "halos" around lights.
• Frequent changes in eyeglass or contact lens prescription.
• Fading or yellowing of colors.
• Double vision in one eye.

At first, stronger lighting and eyeglasses can help deal with cataracts. But if impaired vision affects usual activities, cataract surgery might be needed. Surgery is generally a safe, effective procedure.

Can Rising Pollution Levels In India Worsen Eye Health?

The doctors confirmed that most cases now appear with patients who have allergies, dryness, burning sensations and excessive watering in the eyes. The pollution is not only affecting children, but adults are also equally impacted.

Dr Ikeda Lal, Senior Cornea, Cataract and Refractive Surgery Specialist at Delhi Eye Centre and Sir Ganga Ram Hospital told PTI: "Every year after Diwali, we brace for a rise in eye complaints. The number of patients complaining of itching, redness, and irritation has gone up by almost 50-60 per cent."

A study from 2022 published in the International Journal of Environmental Research and Public Health notes the adverse effects of air pollution on the eyes. Air pollution is a mix of complex gas-phase pollutants and particles that are disbursed into the atmosphere and are harmful.

It comprises:

• Sulfur dioxide
• Nitrogen dioxide
• Carbon dioxide
• Nitrogen monoxide
• Carbon monoxide
• Nitrogen oxides
• Particulate matter 2.5 or PM2.5
• Particulate matter 10 or PM10

Air pollution is known to cause cardiovascular disorders, respiratory tract problems, ocular disease, neurologic disease, cancer, and even death, notes the study.

In terms of its impact on the eyes, the pollutants usually work as irritants, which can cause inflammation and irritation in the eyes.

The cornea is the most sensitive structure in the human body due to its innervation in the ocular surface, which makes it extremely sensitive to environmental agents. The pollutants could thus cause conjunctivitis, which could become a frequent problem.

In addition to that, household pollution could also produce volatile organic compounds; for instance, formaldehyde could cause DNA damage in animal cells, and its carcinogenicity has been assessed by many studies too.