Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.

What Is Gut Microbiome?

Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.

How Does Gut Microbiome Influence Your Health?

The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:

Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.

Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.

Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.

Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.

Gut Microbiome And Weight Management

An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.

Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.

Gut Health And Disease Prevention

The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.

Impact On Heart Health

Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.

Blood Sugar Regulation And Diabetes Risk

The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.

Connection Between Gut And Brain

The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.

Tips For Healthier Gut Microbiome

Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:

• Eat a diverse range of foods: A varied diet rich in fiber, legumes, and fruits promotes microbial diversity.
• Consume fermented foods: Yogurt, kefir, and sauerkraut contain probiotics that enhance gut health.
• Limit artificial sweeteners: Some artificial sweeteners can encourage the growth of harmful bacteria.
• Include prebiotic foods: Bananas, oats, and asparagus contain fibers that nourish beneficial bacteria.
• Breastfeed infants when possible: Breastfeeding promotes a healthier gut microbiome in babies.
• Choose whole grains: Whole grains contain fiber and beneficial compounds that support digestive health.
• Opt for a plant-based diet: Vegetarian diets may reduce inflammation and support a healthier gut microbiome.
• Consume polyphenol-rich foods: Green tea, dark chocolate, and olive oil contain compounds that foster beneficial bacteria.
• Take probiotics if needed: Probiotic supplements can help restore gut balance after disruptions, such as antibiotic use.
• Use antibiotics cautiously: While antibiotics can be life-saving, overuse can harm beneficial gut bacteria.

A new global analysis by the World Health Organization and its cancer research arm, the International Agency for Research on Cancer, has found that prevention could dramatically reduce cancer cases worldwide. The report estimates that 37 percent of all new cancers in 2022, about 7.1 million cases, were linked to causes that can largely be avoided.

The findings are based on data from 185 countries and 36 cancer types and were released ahead of World Cancer Day. Researchers examined 30 risk factors including tobacco use, alcohol, obesity, lack of physical activity, air pollution, ultraviolet radiation and nine cancer causing infections. The report stresses that prevention may be the single most powerful tool available to reduce the global cancer burden.

According to WHO data, tobacco remains the biggest contributor, responsible for about 15 percent of all new cancer cases globally. Infections accounted for around 10 percent while alcohol contributed to roughly 3 percent. Three cancers together made up nearly half of all preventable cases worldwide. Lung cancer was strongly linked to smoking and polluted air, stomach cancer to Helicobacter pylori infection, and cervical cancer to human papillomavirus infection.

WHO cancer control experts said the analysis shows clearly how much cancer risk comes from factors people and governments can act on before the disease even develops.

Differences between men, women and regions

The report shows clear gender differences. Preventable cancer accounted for 45 percent of new cases among men compared with 30 percent among women. Among men, smoking alone contributed to 23 percent of new cancers followed by infections at 9 percent and alcohol at 4 percent. Among women, infections were the largest contributor at 11 percent, followed by smoking at 6 percent and high body mass index at 3 percent.

The burden also varied widely across regions. In women, preventable cancers ranged from 24 percent in North Africa and West Asia to 38 percent in sub Saharan Africa. Among men, East Asia had the highest share at 57 percent while Latin America and the Caribbean recorded the lowest at 28 percent. Researchers say these differences reflect lifestyle habits, environmental exposures, workplace safety standards and public health policies.

The WHO report highlights practical steps that could reduce cancer cases. These include stronger tobacco control laws, limits on alcohol use, vaccination against HPV and hepatitis B, improved air quality, safer workplaces and promotion of healthier diets and physical activity.

Health officials say coordinated action across sectors such as transport, education, labour and energy can prevent millions of cancer diagnoses and lower long term healthcare costs while improving overall population health.

Reality television personality Nicole “Snooki” Polizzi has revealed she has been diagnosed with stage-one cervical cancer after undergoing further testing for previously detected abnormal cells.

The Jersey Shore alum shared in a Feb. 20 TikTok video that a cone biopsy confirmed adenocarcinoma, a type of cancer that develops in gland-lining cells. Doctors discovered the disease less than a month after she first announced the presence of cancerous cervical cells.

“Not the news I was hoping for,” the 38-year-old said, adding that the early detection significantly improved her outlook.

Detected Early After Years Of Tests

Polizzi said she had experienced abnormal Pap smear results for several years before undergoing the procedure that led to the diagnosis. She encouraged followers not to delay screenings out of fear or discomfort, noting early detection made the cancer potentially curable.

Medical teams also informed her that the cancer had not spread deeper into the cervix — an encouraging sign — though adenocarcinoma can be more aggressive and may spread to lymph nodes if untreated.

Further Scans And Likely Surgery

Doctors have scheduled a PET scan to determine whether the cancer has spread elsewhere in the body. Depending on the findings, treatment options include chemotherapy, radiation or surgery.

Polizzi said she is leaning toward a hysterectomy, the surgical removal of the uterus, describing it as the most sensible course of action.

Message to Fans: Don’t Skip Screenings

The television star, a mother of three, thanked supporters for their encouragement and said she plans to keep sharing updates during treatment.

She also stressed the importance of routine check-ups, calling cervical cancer “nothing to joke about” and urging people to seek timely testing, even when it feels uncomfortable or frightening.

What Is Cervical Cancer?

Cervical cancer, also known as cancer of the cervix, begins on the surface of the cervix and involves the growth of abnormal cells in its lining. Cervical cancer is primarily caused by infection with the human papillomavirus (HPV), which is preventable with a vaccine.

There are three main types of cervical cancer:

• Squamous cell carcinoma: This type forms in the lining of the cervix and accounts for about 70% of cases.
• Adenocarcinoma: This type forms in the cells that produce mucus and is less common.
• Mixed carcinoma: This type has features of both squamous cell carcinoma and adenocarcinoma.

Preventive measures, including the HPV vaccine and regular screenings, are crucial in reducing the risk of cervical cancer. Early detection and treatment significantly improve the chances of successful outcomes.

Symptoms of Cervical Cancer

In its early stages, cervical cancer typically doesn’t show any symptoms, which is why regular screening is important to catch it at this stage. Once symptoms do start appearing, they include abnormal vaginal bleeding (in between periods) and unusual vaginal discharge. Pain during sex in the pelvic region is another common symptom. As the cancer worsens, patients may experience more severe symptoms like weight loss, fatigue and leg swelling.

Precancerous changes in cervical cells rarely cause symptoms. The only way to detect abnormal cells that may develop into cancer is through a cervical screening test. If these early cell changes progress into cervical cancer, the most common signs include:

• Vaginal bleeding between periods
• Menstrual bleeding that is longer or heavier than usual
• Pain during intercourse
• Bleeding after intercourse
• Pelvic pain
• Changes in vaginal discharge, such as increased discharge or discharge with a strong or unusual color or smell
• Vaginal bleeding after menopause

These symptoms can be caused by other conditions, but if you are worried or symptoms persist, it is essential to contact your doctor. This is important for anyone with a cervix, including individuals who are straight, lesbian, gay, bisexual, or transgender.

Early signs of cervical cancer can include:

• Pain during sex
• Unusual vaginal bleeding, such as after sex, between periods, after menopause, or following a pelvic exam
• Unusual vaginal discharge that is watery, bloody, and/or has a strong odour

As cervical cancer progresses, it can cause additional symptoms, such as:

• Pelvic pain
• Trouble urinating
• Swollen legs
• Kidney failure
• Bone pain
• Weight loss and lack of appetite
• Fatigue
• Backache
• Stomach pain

It is crucial to note that you might not notice symptoms of cervical cancer until it has advanced. Regular screenings and prompt medical consultation for any concerning symptoms are vital for early detection and effective treatment.

Adolescents who use cannabis could face a significantly higher risk of developing psychotic (doubled), bipolar (doubled), depressive and anxiety disorders, a study shows.

Researchers from Kaiser Permanente, the Public Health Institute's Getting it Right from the Start, the University of California, San Francisco and the University of Southern California, who studied 463,396 adolescents ages 13 to 17 through age 26, found that children between these ages were extremely prone to developing mental illnesses.

Lynn Silver, MD, program director of the Getting it Right from the Start, a program of the Public Health Institute, and study co-author noted: "As cannabis becomes more potent and aggressively marketed, this study indicates that adolescent cannabis use is associated with double the risk of incident psychotic and bipolar disorders, two of the most serious mental health conditions.

"The evidence increasingly points to the need for an urgent public health response - one that reduces product potency, prioritizes prevention, limits youth exposure and marketing and treats adolescent cannabis use as a serious health issue, not a benign behavior."

"Even after accounting for prior mental health conditions and other substance use, adolescents who reported cannabis use had a substantially higher risk of developing psychiatric disorders - particularly psychotic and bipolar disorders.

"This study adds to the growing body of evidence that cannabis use during adolescence could have potentially detrimental, long-term health effects. It's imperative that parents and their children have accurate, trusted, and evidence-based information about the risks of adolescent cannabis use," Kelly Young-Wolff, Ph.D., lead author of the study and senior research scientist at the Kaiser Permanente Division of Research, added.

The observational US-focused study also found that cannabis use was more common among adolescents enrolled in Medicaid and those living in more socioeconomically deprived neighborhoods.

How Does Cannabis Usage In Teens Affect Overall Health?

Strong links have also been found between adolescent cannabis use and mental health issues, including increased risk of depression, anxiety, and, in some cases, schizophrenia or other psychotic disorders.

Additionally, smoking cannabis can lead to breathing problems similar to tobacco, such as chronic bronchitis. It can also cause an increased heart rate, and some studies suggest a higher risk of heart attacks.

Early initiation, especially before age 16, increases the risk of developing Cannabis Use Disorder (addiction). High-potency products can lead to rapid onset of withdrawal symptoms, mood changes, and even physical complications like Cannabis Hyperemesis Syndrome (severe nausea/vomiting)

Why Should Early Cannabis Usage Be Discouraged?

Compared to teens who don't use cannabis, those who do are more likely to drop out of high school or not finish a college degree. Using cannabis can cause several immediate and long-term problems for teens:

• Difficulty Thinking
• Memory Issues
• Poor Coordination
• Attention Problems
• School and Social Troubles
• Cannabis use can also lead to more serious issues that affect a teen's overall life.
• Increased Mental Health Risks

Driving under the influence of cannabis is illegal and unsafe, as it severely slows reaction time. Cannabis reduces coordination and concentration, impacting all the skills necessary for responsible and safe driving.

Around 30 percent of cannabis users are also known to develop an addiction (cannabis use disorder). Failing to quit or choosing the drug over family activities are signs. This risk is higher for frequent teen users.