How Does Your Gut Microbiome Impact Your Overall Health?

Updated Feb 26, 2025 | 07:32 AM IST

SummaryMicroorganisms, or microbes, reside in various parts of your body, but the majority are concentrated in the intestines, particularly in the cecum, a part of the large intestine.
How Does Your Gut Microbiome Impact Your Overall Health?

Credit: Canva

Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.

What Is Gut Microbiome?

Microorganisms, or microbes, reside in various parts of your body, but the majority are concentrated in the intestines, particularly in the cecum, a part of the large intestine. This collection of microbes is referred to as the gut microbiome.

Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.

How Does Gut Microbiome Influence Your Health?

The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:

Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.

Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.

Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.

Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.

Gut Microbiome And Weight Management

An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.

Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.

Gut Health And Disease Prevention

The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.

Impact On Heart Health

Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.

Blood Sugar Regulation And Diabetes Risk

The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.

Connection Between Gut And Brain

The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.

Tips For Healthier Gut Microbiome

Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:

  • Eat a diverse range of foods: A varied diet rich in fiber, legumes, and fruits promotes microbial diversity.
  • Consume fermented foods: Yogurt, kefir, and sauerkraut contain probiotics that enhance gut health.
  • Limit artificial sweeteners: Some artificial sweeteners can encourage the growth of harmful bacteria.
  • Include prebiotic foods: Bananas, oats, and asparagus contain fibers that nourish beneficial bacteria.
  • Breastfeed infants when possible: Breastfeeding promotes a healthier gut microbiome in babies.
  • Choose whole grains: Whole grains contain fiber and beneficial compounds that support digestive health.
  • Opt for a plant-based diet: Vegetarian diets may reduce inflammation and support a healthier gut microbiome.
  • Consume polyphenol-rich foods: Green tea, dark chocolate, and olive oil contain compounds that foster beneficial bacteria.
  • Take probiotics if needed: Probiotic supplements can help restore gut balance after disruptions, such as antibiotic use.
  • Use antibiotics cautiously: While antibiotics can be life-saving, overuse can harm beneficial gut bacteria.

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Rabies Deaths in India: Why People Still Die Despite Effective Vaccines

Health and Me

Updated Sep 16, 2025 | 04:56 PM IST

SummaryRecently, reports have emerged of people dying of rabies despite being vaccinated. Doctors, however, caution that the problem does not lie with medical science but with lack of awareness, and perhaps with a vaccination protocol that needs a change.
Rabies Deaths in India: Why People Still Die Despite Effective Vaccines

Credits: Canva

A 47-year-old autorickshaw driver from Royapettah, who had received a full course of vaccination after being bitten by a stray dog in July 2025, died of rabies at the Rajiv Gandhi Government General Hospital (RGGGH). He is the 22nd person to succumb to the disease in Tamil Nadu this year.

His death has left experts asking a difficult question, if protocols were followed, why are people still dying? Public health specialists suggest this may not just be a failure of administration, but a sign that India’s long-standing rabies protocol itself needs re-examination.

What Is Rabies?

Rabies is one of the deadliest yet most preventable viral infections known to humanity. The World Health Organization describes it as a vaccine-preventable zoonotic disease that attacks the central nervous system. In nearly 99% of human cases, the virus is transmitted by dogs.

“Rabies infects mammals, including dogs, cats, livestock and wildlife. It spreads to people through saliva, usually by bites, scratches, or direct contact with mucous membranes such as the eyes, mouth, or open wounds. Once symptoms appear, rabies is virtually 100% fatal,” explains Dr. Surrinder Kumar, MBBS, General Physician.

ALSO READ: Bird Flu In US: Are Cats Spreading A Deadly Disease?

Why Rabies Deaths Still Happen in India?

Despite the availability of effective vaccines, India continues to record thousands of rabies deaths every year. Dr. Surrinder says the problem is not medical science but lack of awareness and timely action. “Rabies remains endemic in India. Vaccines and immunoglobulins work, but the virus attacks the central nervous system and once symptoms begin, it is almost always fatal. The real challenges are late treatment, poor awareness, and preventive gaps.”

For those unversed, Rabies immunoglobulin is a medication made up of antibodies against the rabies virus. It is used to prevent rabies following exposure.

According to Dr Surrinder, the main reasons are:

  1. Delayed or No Medical Attention: Many victims dismiss dog bites as minor and fail to seek immediate treatment.
  2. Lack of Awareness: In rural and semi-urban areas, people often don’t know the importance of post-exposure vaccination.
  3. Reliance on Home Remedies: Turmeric, lime, oils, and other traditional remedies are still used, offering no protection.
  4. Incomplete Vaccination: Even if treatment begins, many patients drop out midway, making it ineffective.
  5. Limited Access to Rabies Immunoglobulin (RIG): For severe bites, RIG is essential along with vaccines, but its high cost and patchy availability block timely use.

The Ground Reality of Rabies Treatment

Dr Shaswath Kumar G. S., a Bengaluru-based veterinarian, explains that anyone bitten by a stray dog without a known vaccination history must undergo the full course of rabies shots, along with immunoglobulin injected directly at the bite site. Before this injection is given, patients are required to undergo an allergy test, which often causes hesitation. He also points out that it may not always be free in government hospitals. The procedure itself is painful since the immunoglobulin is delivered directly into the wound.

ALSO READ: Why 1 In 6 U.S. Parents Are Rejecting Vaccine Recommendations

Alongside immunoglobulin, at least five separate rabies vaccine doses are necessary. These, Dr. Shaswath says, are not without side effects, as “every time people take the vaccine, they get fever.” While cities are able to conduct mass vaccination campaigns, rural areas face significant challenges in this regard.

He further stresses that rabies is not confined to dog bites alone. The virus can also spread from other animals, and in rare cases even from humans, if infected saliva comes in contact with open wounds or mucous membranes. “A bite isn’t always necessary,” he warns.

Dr. Ranjeet Singh, Professor and Head of General Medicine at NIIMS Medical College and Hospital, echoes the same concerns. He emphasises that rabies deaths in India do not reflect a failure of the vaccine itself. Instead, the main reasons are late treatment, lack of awareness, incomplete vaccination, shortage of immunoglobulin, and limited access in rural areas.

Is India’s Rabies Vaccination System Flawed?

Experts stress that it would be wrong to doubt the vaccine itself. Doing so, they warn, could undermine public trust. “We have a robust programme. The National Action Plan for Rabies Elimination by 2030 (NAPRE) is already in place, and the vaccine’s efficacy is very strong,” doctors underline.

India follows the WHO-approved five-dose rabies vaccine protocol, with immunoglobulin recommended for severe (Category III) bites. But the bigger question, they say, is whether the protocol assumes ideal conditions, which is immediate wound washing, uninterrupted cold chain storage, and trained professionals administering injections at the wound site. In reality, these conditions are not always met.

Common Mistakes After a Dog Bite Which Can Lead To Rabies

Dr. Ranjeet Singh highlights errors that often cost lives:

  1. Not washing the wound immediately: The first step after a bite is washing with soap and running water for at least 15 minutes. Most skip it.
  2. Covering the wound too soon: Tying cloth or applying bandages traps the virus inside.
  3. Applying irritants: Substances like chili, lime, or ash worsen the wound and delay treatment.
  4. Ignoring minor bites or scratches: Even tiny wounds can transmit rabies if saliva enters.
  5. Stopping the vaccine midway: Completing the full course is essential; partial doses give no real protection.

To end rabies deaths in India, awareness must go hand in hand with medical access. Every bite, no matter how small, needs immediate action: wash, vaccinate, and if severe, take immunoglobulin.

“Rabies is 100% preventable but 100% fatal if ignored. No bite should ever be taken lightly. The key is simple, wash, vaccinate, and complete the course,” concludes Dr. Surrinder Kumar.

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Do This 1 Thing Before You Pop A Pill For Your Migraine, According To Pharmacist

Updated Sep 16, 2025 | 05:14 PM IST

SummarySometimes big problems can have a simple solution. We have all had days when the headache is so bad you have to resort to medicine. However, did you know that, before you grab your headache medicine, you should check whether you actually need medicine? Here’s a trick that may help.
Do This 1 Thing Before You Pop A Pill For Your Headache According To Pharmacist

(Credit- Canva)

Sometimes a simple headache can derail your entire day. It slows down your work, causes you issues etc. When that happens, the easiest way to get rid of it is by taking medicine. However, did you know, you may be able to avoid taking the medicine by doing a simple check before?

Sometimes, the cause isn't a lack of medicine—it's a lack of hydration. Dehydration is a very common cause of headaches, and it's often overlooked. In a post, Suzanne Soliman, a US board certified pharmacist, explained that your headache may be a simple issue, that may not need medicine. Before you grab a pain reliever, try this simple trick: Drink a full glass of water with a small pinch of salt. The salt helps your body absorb the water better.

But how does salt water help you get rid of headaches? Is there medical backing to this or is it a placebo trick that helps some people?

Can Salt Water Treat a Migraine?

For some people, drinking salt water can help relieve a migraine, but it depends on the cause. Here are a couple of reasons why it might work:

You're dehydrated

If you've been sweating a lot, you lose both water and salt. Rehydrating with a glass of water and a pinch of salt can restore your body's balance and ease the headache.

You're on a low-salt diet

Several studies, like a 2021 study published in the Medical Science journal, suggest that if your body is used to a high-salt diet (like the average American diet), suddenly reducing your sodium intake can trigger a "withdrawal" headache. In this case, eating or drinking something salty might help.

However, the evidence isn't clear, and drinking too much salt water can make you feel sick. If you want to try this, only add a tiny pinch of salt to a full glass of water. A better way to get more salt might be through salty snacks or a sports drink with electrolytes.,

Can Eating Salt Prevent or Worsen a Migraine?

There's a complex link between salt and migraines. Some people who eat a lot of salt regularly report fewer migraine symptoms, possibly because their bodies are used to a high-sodium diet.

According to the 2021 study, the relief people feel when they eat salty foods during a migraine isn't a cure, but rather a temporary relief from withdrawal symptoms. This might help explain why some studies have found that people who eat more salt tend to have fewer migraines—their bodies are simply getting the high amount of salt they're used to.

Can Too Much Salt Trigger Migraine?

On the other hand, consuming too much salt can also be a migraine trigger. Eating too much salt can increase your blood pressure, which is a known cause of headaches and migraines. Studies have shown that for some people, a high-salt diet can actually make a migraine episode last longer.

Also Read: Frank Grillo On Steroid Use: 'I’m Not Cheating At Anything Except Aging'

A 2023 study published in JAMA included 213 people with a median age of 61. The group was 65% female and 64% Black. Each person followed three different diets: their usual diet, a high-salt diet, and a low-salt diet.

If your headaches are related to high blood pressure, a low-salt diet may be more beneficial

Salt's effect on migraines is different for everyone. It might help if your headache is caused by dehydration or a sudden drop in sodium, but it could also trigger a migraine or make it worse if you have high blood pressure or are sensitive to salt. Always talk to your doctor to figure out what's best for you and your symptoms.

Salt's effect on migraines is different for everyone. It might help if your headache is caused by dehydration or a sudden drop in sodium, but it could also trigger a migraine or make it worse if you have high blood pressure or are sensitive to salt. Always talk to your doctor to figure out what's best for you and your symptoms.

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Frank Grillo On Steroid Use: 'I’m Not Cheating At Anything Except Aging'

Updated Sep 16, 2025 | 05:08 PM IST

SummaryKnown for his superhero roles and fitness, Frank Grillo opened up about his health habits, physique and the challenges he faced in a podcast interview. Not shying away from talking about steroids and Testosterone Replacement treatment, “There’s nothing wrong with using those drugs” he said. Here is what you need to know about it.
Frank Grillo On Steroid Use: 'I’m Not Cheating At Anything Except Aging'

(Credit- Frank Grillo Instagram)

Frank Grillo, the 60-year-old actor known for his roles in superhero films like Superman Peacemaker, recently opened up about how he gets in shape for the big screen. In a recent interview on the Men’s Health “Strong Talk” podcast, he candidly discussed his use of steroids, revealing that many actors use similar methods to prepare for roles.

Grillo spoke on his use of the steroid medication, and gave his view on its criticism. As a part of his Testosterone Replacement Therapy treatment, which helps improve symptoms of low testosterone, he took the medication, and it helped him deal with many age-related health issues.

Why Does Frank Grillo Use Steroids?

Grillo shared that about six years ago, he found out his natural testosterone levels were low. To fix this, he started using testosterone replacement therapy. He says this treatment has helped him in many ways, like improving his sleep, speeding up his recovery after workouts, and making him feel happier in general. Grillo doesn't hide his use of steroids.

Also Read: Do This 1 Thing Before You Pop A Pill For Your Headache According To Pharmacist

He pushes back against people who call it “cheating,” arguing that as an actor, he isn’t competing in a sport like football or wrestling. Instead, he’s simply trying to look the part for a movie role and, in his words, is "not cheating at anything except aging." He also points out that when actors are hired for a superhero movie, there’s an expectation to look a certain way, and sometimes that means using medications like Anavar, a steroid that acts like testosterone.

How Do You Build ‘Superhero’ Physiques?

Grillo claims that what he's doing is not uncommon in Hollywood. He believes that many other actors also use steroids to quickly achieve dramatic body transformations for their roles. He mentioned that drugs like Anavar and Deca, which is another type of steroid, are now often prescribed by doctors, which means their use can be monitored by a medical professional.

Grillo was very clear that incredibly muscular bodies aren't natural. He explains that it's just not realistic for someone to look one way for most of the year and then suddenly gain 35 pounds of muscle. He says that while many actors might not want to talk about it, everyone in the industry knows exactly what’s going on.

What Is Anavar/ Oxandrolone?

According to US National Cancer Institute, Oxandrolone is a man-made drug that's very similar to testosterone, a natural hormone in our bodies. It works by attaching to and activating certain receptors, which are like tiny switches in our cells. Because of this, oxandrolone is used for several reasons, including:

Testosterone replacement therapy: To help men who have low testosterone levels.

HIV-wasting syndrome: To help people with HIV who are losing a lot of weight and muscle.

Other conditions: To help the body hold onto more nitrogen (which is key for building muscle) and to increase lean muscle mass.

How Does Aging Effect Testosterone For Men?

According to Hospital for Special Surgery (HSS), as men get older, it's common for them to experience a natural decline in both testosterone and muscle mass. While this is a normal part of aging, there are ways to fight back against it.

Testosterone is a crucial hormone for men. It helps build muscle by creating proteins, which in turn increases muscle strength. Starting around age 40, a man's testosterone levels gradually drop by about 1-2% each year. This decline can lead to symptoms like fatigue, hair loss, and depression, but many men don't realize what's causing these changes because testosterone levels aren't always checked during a routine doctor's visit.

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