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Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.
Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.
The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:
Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.
Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.
Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.
Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.
An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.
Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.
The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.
Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.
The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.
The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.
Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:
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Ramzan, the holiest month in Islam, marked by dawn-to-dusk fasting, poses health risks for people with diabetes. Health experts urge patients to consult their doctors before observing the fast.
Ramzan is a period of intense spiritual reflection, self-discipline, and devotion for Muslims worldwide. During the month-long fasting period, the believers refrain from eating and even drinking (including water), from dawn to sunset.
The faithful eat a modest meal (sehri) before the first light of dawn to provide energy for the day. The fast is broken at sunset, traditionally starting with dates and water, followed by a larger meal (iftar).
According to health experts, for individuals whose diabetes is well controlled, fasting may be possible with proper adjustments.
"Diabetes requires regular monitoring, balanced meals, and timely medication. When eating patterns change during Ramzan, blood glucose levels can fluctuate. That is why I strongly recommend consulting your doctor before you plan to fast,” Dr. Saptarshi Bhattacharya, Senior Consultant, Endocrinology, Indraprastha Apollo Hospitals, told HealthandMe.
The expert advised people not to skip sehri, and to include complex carbohydrates such as whole grains, along with protein like eggs, dal, or curd, and plenty of fluids to help maintain stable glucose levels throughout the day.
At iftar, avoid overeating. Start with light, balanced food and limit fried items, sweets, and sugary drinks, as these can cause a sudden spike in blood glucose, Dr. Bhattacharya said.
Type 2 Diabetes patients with good glycemic control, lifestyle management, or stable oral medications can fast safely.
However, those on multiple insulin doses, with complications, or with poor control are considered moderate to high risk, Dr. Kartik Thakkar, Consultant Medicine, Ruby Hall Clinic, told HealthandMe.
The health expert also noted that most Type 1 diabetes patients are considered high risk, especially those with brittle diabetes, frequent hypoglycemia (low blood sugar), or a history of diabetic ketoacidosis (DKA). Many are medically advised not to fast, particularly if glucose control is unstable.
Children and adolescents with type 1 diabetes are considered high risk and are usually advised against fasting due to the unpredictable nature of insulin requirements.
Dr. Thakkar said that such individuals fall into the very high-risk category and are medically exempt from fasting.
The expert also suggested clinical tests to determine whether a diabetic patient is fit to fast. These include:
A diabetic patient must break the fast if:
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A new study has shown that people who survived COVID-19 infections are more likely to develop obstructive sleep apnea (OSA) for years after the infection with the SARS-CoV-2 virus.
OSA is a common and serious sleep disorder that causes the throat muscles to relax and block the airway, resulting in fragmented, nonrestorative sleep, low blood oxygen, and loud snoring.
The February 2026 study, published on the preprint server medRxiv, found that people with both severe and non-severe COVID infections are at higher risk of developing sleep apnea and other sleep issues for 4.5 years.
"SARS-CoV-2 infection is independently associated with increased risk of new-onset OSA. These findings support targeted screening in post-COVID populations,” said Sagar Changela, Department of Radiology, Albert Einstein College of Medicine, in the paper.
Although an infection with the SARS-CoV-2 virus has been associated with long-term respiratory and neurological conditions, its role in new-onset OSA remains unclear.
The retrospective study, which has not been peer-reviewed, involved 910,393 patients. The results showed that patients hospitalized due to COVID were 41 percent at risk of new onset of OSA.
One-third of people with mild COVID infection, who weren't hospitalized, also suffered from sleep issues.
The researchers also linked OSA to cardiovascular, metabolic, and cognitive morbidity. The team found that OSA increased the risk of heart failure and pulmonary hypertension among hospitalized COVID patients, compared to those with mild infections.
On the other hand, the non-hospitalized COVID patients were significantly more likely than controls to develop obesity.
Further analyses showed that the risk of new-onset OSA was higher in hospitalized COVID patients with asthma and those who were younger than 60 years. Notably, women were also found at greater risk than men, while vaccination status did not vary by risk.
According to the team of researchers, the major factors for OSA among COVID patients are low-grade systemic inflammation after a SARS-CoV-2 infection that reduces upper-airway neuromuscular control.
In addition, the higher levels of inflammatory cytokines often seen in long-COVID patients can also affect respiratory drive and upper-airway stability -- key factors for OSA.
Sleep apnea is a serious sleep disorder where a person's airway can collapse completely or partially. It causes breathing lapses during sleep, and the body stops breathing many times while an individual is asleep. It also weakens throat muscles, leading to airway collapse during sleep. The decrease in oxygen saturation can also lead to death.
While OSA is the most common type of the sleep disorder, other types include central sleep apnea and complex sleep apnea.
Obesity is the major cause of this disorder, and loud snoring is the most common symptom. The person suffering from the condition feels tired, even after getting adequate sleep.
Treating sleep apnea is key to preventing long-term health complications such as cardiovascular disease, hypertension, diabetes, stroke, and increased mortality.
CPAP machines, oral appliances, and lifestyle modifications are common and effective treatment measures.
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Are you still sitting down to put your sock on? A new study says that it may be an indicator that you are getting old. A research commissioned by American Pistachio Growers, partnered with British actor and comedian John Thomson, teamed up with nutritionist Rob Hobson to embrace aging positively. The research looked at common day-to-day signs of aging and found that 39 per cent of those surveyed (out of total 5,000 people over 40s) wanted a quiet drink over a night and they cared less about fashion. The research revealed that this could be an indicator that "you are creeping into the old category".
About one in three respondents (33 per cent) said they first felt they were no longer young when they caught themselves groaning while bending down.
Other telltale signs included discussing aches and pains with friends (30 per cent), preferring a quiet pub over a noisy bar (27 per cent) and naturally waking up at 6 am (12 per cent).
The survey also found people typically start feeling “not young” around 50, although 38 per cent believe old age now begins in the 80s rather than the 50s or 60s.
At the same time, 36 per cent said they have adopted habits to stay youthful, such as taking vitamins or supplements, choosing healthier snacks (19 per cent) and increasing protein intake (17 per cent).
"Getting older is inevitable, but you can still live life to the full. It is about embracing experience, having a laugh about the realities of aging and making small changes that actually make a difference. You don't need to overhaul your life, just make some healthy tweaks to your daily routine," said John.
Interestingly, only 36 per cent of people in the survey actually said they feel old. In fact, 27 per cent reported feeling more comfortable in their own skin now than when they were younger, and 18 per cent of those over 30 said they are more satisfied with life than they were in their thirties.
Lifestyle choices also seem to shift with age. Around 39 per cent now prioritize comfort over fashion, 34 per cent enjoy going for walks and 19 per cent have taken up gardening or DIY projects. Healthy eating becomes more intentional too, with 60 per cent of men and 61 per cent of women saying they are more health conscious than before.
Their motivations are practical: avoiding illness (59 per cent), staying active (58 per cent) and maintaining independence as they age (47 per cent).
TV nutritionist Rob Hobson, who partnered with American Pistachio Growers to promote the nut as an easy addition to a healthy routine, said ageing is less about decline and more about awareness. “Getting older isn’t about slowing down, it’s about making smarter choices,” he said. “Simple habits like eating nutrient-rich snacks, staying active and prioritizing sleep can help you feel youthful for longer. Age is just a number, but how you fuel your body makes all the difference.”
Suzanne Devereaux-McKinstrie, spokesperson for the non-profit organization, echoed the sentiment, saying later years can be empowering. “Getting older isn’t just about limitations, it’s about opportunities. It’s the perfect time to explore new hobbies, prioritise wellbeing and celebrate the confidence that comes with experience,” she said, adding that diet plays a key role in staying strong and active.
Top 25 Signs That Reveals You Are Getting Older
| 1 | Talking about aches and pains with friends |
| 2 | Groaning when bending down |
| 3 | Preferring quiet venues to noisy ones |
| 4 | Preferring a quiet drink over a night out |
| 5 | Enjoying an early night |
| 6 | Not caring about the latest fashion trends |
| 7 | Thinking that new music isn’t as good as it used to be |
| 8 | A recurring ache that doesn’t disappear |
| 9 | Using phrases like ‘back in my day’ or ‘remember when….?’ |
| 10 | Sitting down to put socks on |
| 11 | Caring less about how you look |
| 12 | Taking shoes off as soon as you get inside – slippers have become a necessity! |
| 13 | Noticing something you wore in your youth is now back in fashion |
| 14 | Starting conversations with ‘Do you remember when…?’ |
| 15 | Reading menus at arm’s length |
| 16 | Talking to yourself |
| 17 | Moaning about politics |
| 18 | Feeling more confident/self-assured |
| 19 | Getting up at 6am naturally |
| 20 | First “Who?” when watching the Brit Awards |
| 21 | Looking forward to gardening |
| 22 | Feeling confounded by AI |
| 23 | Listening to the radio or podcasts instead of club music |
| 24 | Getting excited about new home appliances |
| 25 | Checking the weather forecast hourly |
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