Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.

What Is Gut Microbiome?

Microorganisms, or microbes, reside in various parts of your body, but the majority are concentrated in the intestines, particularly in the cecum, a part of the large intestine. This collection of microbes is referred to as the gut microbiome.

Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.

How Does Gut Microbiome Influence Your Health?

The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:

Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.

Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.

Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.

Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.

Gut Microbiome And Weight Management

An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.

Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.

Gut Health And Disease Prevention

The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.

Impact On Heart Health

Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.

Blood Sugar Regulation And Diabetes Risk

The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.

Connection Between Gut And Brain

The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.

Tips For Healthier Gut Microbiome

Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:

• Eat a diverse range of foods: A varied diet rich in fiber, legumes, and fruits promotes microbial diversity.
• Consume fermented foods: Yogurt, kefir, and sauerkraut contain probiotics that enhance gut health.
• Limit artificial sweeteners: Some artificial sweeteners can encourage the growth of harmful bacteria.
• Include prebiotic foods: Bananas, oats, and asparagus contain fibers that nourish beneficial bacteria.
• Breastfeed infants when possible: Breastfeeding promotes a healthier gut microbiome in babies.
• Choose whole grains: Whole grains contain fiber and beneficial compounds that support digestive health.
• Opt for a plant-based diet: Vegetarian diets may reduce inflammation and support a healthier gut microbiome.
• Consume polyphenol-rich foods: Green tea, dark chocolate, and olive oil contain compounds that foster beneficial bacteria.
• Take probiotics if needed: Probiotic supplements can help restore gut balance after disruptions, such as antibiotic use.
• Use antibiotics cautiously: While antibiotics can be life-saving, overuse can harm beneficial gut bacteria.

Days after eagle-eyed fans spotted Nick Jonas stepping out of the Golden Globes during the Nikki Glaser-hosted show in Los Angeles, the popstar has now revealed what led to him there.

In an X video from January 11, Jonas was seen standing alone outside of a tent at the Beverly Hilton hotel surrounded by palm trees and green foliage, looking like he was taking a breather while sipping from a glass bottle of water and rubbing his chin.

As the clip began to go viral online, users shared their guess on why he had to exit the ceremony, commenting, "Social anxiety got the best of him." Soon after, he did reveal that he anxiety had "hit him like a gut punch" on X.

Living with Type 1 diabetes, Jonas has previously spoken about the emotional challenges of managing a chronic condition and how it has affected his life.

What Is Social Anxiety?

As explained by Dr Sanil Sinhasan, Consultant Psychiatrist at Mind Care Clinic and SRV Hospital, Mumbai, to Health Shots: "Social anxiety disorder is an intense fear of being judged, rejected, or embarrassed in social or performance situations.

"People with social anxiety often worry excessively about how they look, speak or are perceived by others."

This kind of anxiety is typically triggered by meeting new people, public speaking or even everyday interactions like eating in public, stemming from fears of negative evaluation by others.

Symptoms include blushing, sweating, trembling, rapid heartbeat, nausea, dizziness, trouble speaking, stomach issues. If left untreated, social anxiety can become debilitating as it can also cause fast, shallow breathing, muscle tension, suffocation, symptoms that can intensify anxiety further and lead to serious medical events.

How To Overcome Social Anxiety?

Experts recommend practicing deep breathing and mindfulness to ease social anxiety in public settings. Additionally, lifestyle changes such as exercise, sleep nda healthy diet with mental strategies like challenging negative thoughts and shifting focus outward can also help.

Professional therapies such as Cognitive Behavioral Therapy (CBT) and medication such as antidepressants (SSRIs/SNRIs) can offer deeper solutions for managing fear and building skills.

Regular physical activity can also help release endorphins and reduce tension as well avoiding excess caffeine can support mental health.

Mental health experts also recommend opening up to loved ones and avoiding isolation. Speaking to loved ones and sharing how you’re feeling can help ensure your current state doesn’t aggravate.

Doctors also advise speaking therapist if social anxiety significantly impacts your life as professional help is crucial for lasting change.

Wondering if abnormal bleeding, pelvic pain and leg swelling are signs of something fatal?

According to Dr Ninad Katdare, Consultant Surgical Oncologist, Jaslok Hospital & Research Centre, they may be symptoms of cervical cancer. While many may expect drastic signs such as severe pain, heavy bleeding or obvious illness, identifying certain symptoms can help with early diagnosis and treatment.

Cervical cancer develops in a women's cervix (uterus opening) due to abnormal cell growth, primarily caused by persistent HPV infection, a common infection that's passed through sexual contact.

When exposed to HPV, the body's immune system typically prevents the virus from causing damage however, in a small percentage of people, the virus can survive for years and pave the way for some cervical cells to become cancerous.

Treatment involves surgery, radiation, and chemotherapy, with early detection significantly improving outcomes, though it remains a major cancer in low-income countries. Cervical cancer can also be prevented through vaccination and regular screening (Pap/HPV tests).

Dr Katdare told News18: "In its early stages, it is often more of a whisper than a shout. As a cancer surgeon who has treated hundreds of women with gynaecological cancers, I can say with confidence that recognising these subtle cues can lead to earlier diagnosis and significantly better outcomes."

He recommends looking out for these early signs:

1. Intermenstrual Bleeding

Intermenstrual bleeding occurs between regular menstrual periods, ranging from light spotting to heavier flow, often linked to hormonal shifts, ovulation or infections (cervicitis). However, according to Dr Katdare, this sign should not be ignored as it is one of the most common early warning signs of cervical cancer.

2. Changes In Vaginal Discharge

Vaginal discharge is a normal, natural fluid that cleans and protects the vagina and can vary in color (clear to white), consistency (watery to thick) and amount throughout the menstrual cycle.

But Dr Katdare warns that any sudden or abnormal changes in discharge may be a symptom of the cancer. “Because discharge issues are commonly linked to infections, many women self-medicate or delay seeking care," he said. “While infections are far more common, chronic or unusual discharge especially in older women requires thorough evaluation."

Discharge may become persistent, watery, foul-smelling, or tinged with blood or pink, brown, or rust-colored if you're suffering from this kind of cancer.

3. Persistent Pelvic Pain

Consistent pelvic pain particularly that occurs outside the menstrual cycle or during sexual intercourse should be a point of concern. According to Dr Katdare, "Pain during intercourse, or dyspareunia, is especially important. It should not be dismissed as ‘just dryness’ or an age-related change. In cervical cancer, this pain may result from inflammation or tumour growth involving the cervix and surrounding tissues."

4. Leg Swelling

Unnatural and unexplained leg swelling of one leg, particularly if it occurs on one side may suggest that the cancer is progressing and spreading in the body. “This happens due to pressure on pelvic blood vessels," explained Dr. Katdare, “and should not be ignored."

5. Urinary And Bowel Symptoms

As cervical cancer advances to higher stages, it can begin to affect nearby organs including the bladder and kidneys. Symptoms such as frequent urination, difficulty emptying the bladder, constipation, or rectal discomfort may also begin to develop.

“These symptoms are often evaluated in isolation because they don’t seem related to the cervix," said Dr Katdare, “which can delay the correct diagnosis."

Ultimately the expert advised: "“Cervical cancer does not always announce itself loudly,. Sometimes, it leaves silent clues. The sooner you listen to them, the better the outcome. If something feels ‘off,’ trust that instinct and seek medical advice. Early action can make the difference between a curable disease and a life-altering diagnosis."

Angina, a symptom of coronary artery disease, is a type of chest pain caused by the heart muscle not getting enough oxygen-rich blood, usually due to narrowed coronary arteries from plaque buildup.

Itis often described as squeezing, pressure, or heaviness in the chest, potentially radiating to arms, neck, jaw, or back and at times, can feel like indigestion. Experiencing an angina is warning sign of heart disease, not of a heart attack.

However, Shexiang Tongxin Dropping Pill (STDP), a Chinese traditional medicine that can help ease angina pain as it helps improve blood flow and protects heart microcirculation through its anti-inflammatory, anti-oxidant and anti-apoptotic (promoting cell survival) characteristics, according to an EMJ study.

What Is Shexiang Tongxin Dropping Pill?

STDP is essentially a complex herbal preparation containing ingredients like artificial musk, ginseng, borneol, toad venom as well as bezoar and has been approved for use by the Chinese FDA (now National Medical Products Administration).

In this a randomized controlled study, 200 adults with angina and coronary slow flow phenomenon were assigned to receive either STDP or a placebo. The study measured coronary blood flow using corrected TIMI frame count (CTFC).

Patients who received STDP had improved blood flow in two major coronary arteries, while those given placebo showed no improvement. The improvement with STDP was significantly greater than with placebo.

The scientists concluded that using STDP to increase blood flow in the body was beneficial with no major safety concerns reported during the trial, allowing them to conclude that this Chinese medication can help the flow of blood through the heart’s smallest blood vessels, which supply oxygen and nutrients to the heart muscle with no side-effects.

Researchers are yet to conclude how the medication works and helps the heart.

Coronary Artery Disease: The Silent Killer

Despite being as a common heart disease, coronary artery disease (CAD) develops over years and has no clear signs and symptoms apart from chest pain and a heart attack. The illness begins due to a buildup of fats, cholesterol and other substances known as plaque in and on the artery walls.

Over time, this can cause narrowing or blockage of the coronary arteries and block the supply of oxygen-rich blood to heart which can lead chest pain (angina), shortness of breath and ultimately, heart attacks.

Typically, those above the age of 45, having a biological family member with heart disease, lack of sleep, smoking, consuming saturated fats along with other autoimmune diseases such as lupus and rheumatoid arthritis can increase the risk of developing CAD.

Treatment options may include medicines and surgery. Eating a nutritious diet, getting regular exercise and not smoking can help also prevent CAD and the conditions that can cause it.

Nearly one in 10 Indian adults suffer from CAD and about two million people die from the disease annually. Apart from this, about 18 to 20 million American adults aged 20 and older are also affected about the disease.

How Much You Should Exercise To Prevent CAD?

The American Health Association recommends performing at least 150 minutes per week of moderate-intensity aerobic activity such as brisk walking, dancing and gardening or 75 minutes per week of vigorous aerobic activity, such as hiking, running, cycling or and playing tennis or a combination of both, preferably spread throughout the week to maintain heart health.

Moreover, regular exercise can also reduce the risk of Type 2 diabetes, high blood pressure, dementia and Alzheimer’s, several types of cancer. It can also help improve sleep, cognition, including memory, attention and processing speed.

Dr Hayes recommends opting for a cardiac evaluation such as an electrocardiogram, or EKG; stress test; a cardiac MRI or CT scan to generate images of your heart if you notice changes in your ability to exercise or cannot perform consistent levels of exercise.