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Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.
Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.
The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:
Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.
Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.
Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.
Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.
An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.
Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.
The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.
Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.
The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.
The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.
Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:
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As measles continues to spread across the United States, with recent case numbers climbing to their highest level in 33 years, growing numbers of Americans are becoming concerned about how at risk they may be.
Health officials in Philadelphia confirmed a potential measles exposure at Philadelphia International Airport and several public transport locations across the city in early January. The Centers for Disease Control and Prevention has also flagged earlier measles outbreaks across Pennsylvania, New Jersey, and New York City.
Adding to the concern, infectious disease tracker BMJGroup reported that measles cases recorded in 2025 are the highest seen since at least 1992.
Against this backdrop, it is important to understand whether measles can be fatal and to recognise the symptoms that should not be ignored.
Yes, measles can be deadly and carries a significant risk of death, according to the Centers for Disease Control and Prevention.
“Measles can lead to serious health complications, including pneumonia, inflammation of the brain known as encephalitis, and death,” the CDC states. “Between one and three out of every 1,000 people infected with measles will die. Around one in five people with measles will require hospital care, and one in every 20 children with measles develops pneumonia, which is the leading cause of measles-related deaths in young children.
“One in every 1,000 people with measles will experience brain swelling, which can result in permanent brain damage.”
According to the Mayo Clinic, measles symptoms usually appear in three distinct stages.
Stage 1: Incubation period (10 to 14 days)
During this phase, there are typically no noticeable or warning symptoms.
Stage 2: Early symptoms begin
Symptoms at this stage may include a dry cough, fever, red and inflamed eyes known as conjunctivitis, a runny nose, and a sore throat.
Stage 3: Acute illness and rash
“In the third stage, a rash begins to develop, usually starting on the face. Small white spots called Koplik spots may appear inside the mouth two to three days after symptoms first appear,” the Mayo Clinic explains. “The measles rash typically shows up three to five days after the initial symptoms.
“Over the following days, the rash spreads to the arms, torso, and legs. Alongside the rash, fever often rises rapidly and can exceed 105 degrees Fahrenheit,” the guidance continues. “Eventually, the fever subsides, and the rash fades from the body starting at the head and moving downward.”
“If individuals aged six months or older are exposed to measles and do not have immunity from prior infection or vaccination, they can receive the measles vaccine within three days of contact with the virus,” the Mayo Clinic advises. “After vaccination, quarantine at home is not required.
“For children up to 11 months old who are exposed and are not immune, a dose of antibodies known as immune globulin can be given within six days of exposure to help the body fight the infection.”
Receiving this antibody treatment requires a 21-day quarantine period.
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The NHS has issued advice for anyone taking a widely prescribed medication, warning of possible “serious” side effects. If you are currently on atorvastatin, it’s important to be cautious about what other medicines or supplements you take alongside it.
Atorvastatin belongs to a class of drugs called statins, which help lower cholesterol levels. It is usually prescribed for people with high cholesterol to reduce the risk of heart disease, including heart attacks and strokes.
Your GP may also recommend atorvastatin if you have a family history of heart disease or a long-term condition such as type 1 or type 2 diabetes or rheumatoid arthritis. As with any medicine, it’s vital to follow official guidance on how to take it safely.
On its website, the NHS lists certain “cautions with other medicines.” This means you should check that atorvastatin is safe to take alongside any other drugs or supplements.
The NHS explained: “Some medicines can affect the way atorvastatin works and can increase the chances of you having serious side effects, such as muscle damage.” You should tell your doctor or pharmacist if you are taking any of the following:
If you need to take one of these medicines while on atorvastatin, your doctor may:
These are not all the drugs that can interact with atorvastatin. “For a full list, see the leaflet in your medicine packet or speak to your pharmacist,” the NHS said.
The health service also advised checking with your doctor or pharmacist before taking supplements like St John’s wort or CoQ10 while on atorvastatin.
The NHS lists these common side effects, which affect more than one in 100 people:
“Drinking large amounts of alcohol regularly increases the risk of side effects and liver problems while taking atorvastatin,” the NHS added. “If side effects make you want to stop taking the medicine, speak to your doctor first. They may be due to another cause, and your doctor can suggest lowering the dose or switching medicines.”
Stop taking atorvastatin and contact a doctor or call 111 immediately if you experience:
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Keeping the television on while falling asleep or leaving a light on in the bedroom may feel reassuring, but new international research suggests it could seriously affect heart health. A recent study has found that exposure to light at night significantly raises the risk of heart disease, even if a person believes they are sleeping well.
The findings come from a large, long-term study carried out by researchers in Australia and the United States. The team followed nearly 90,000 adults in the United Kingdom over a period of nine years. Participants were given light sensors to accurately measure how much light they were exposed to during sleep.
Researchers tracked cases of heart attack, heart failure, and stroke throughout the study period. The results were striking. Compared to people who slept in complete darkness, those exposed to light at night faced a 56 percent higher risk of cardiovascular problems. The risk of heart failure increased by 47 percent, while the likelihood of coronary artery disease rose by 32 percent. The study noted that this risk was particularly higher among women. The risk of stroke was also found to be up to 30 percent higher.
According to the research, published in JAMA Network Open, the main reason behind this increased risk is disruption of the body’s circadian rhythm. This internal biological clock regulates sleep, hormone release, metabolism, and other vital functions.
Artificial light at night interferes with this natural rhythm, pushing the body into a state of imbalance. Over time, this ongoing disruption places added strain on the cardiovascular system. Researchers warned that for people over the age of 40, exposure to light during sleep is emerging as a significant risk factor for heart disease.
Professor Frank Scheer, a neuroscientist at Brigham and Women’s Hospital, believes doctors should look beyond sleep duration when assessing patients’ sleep habits. He says physicians should also ask about bedroom conditions, including light exposure.
“There is no harm in keeping the bedroom completely dark,” he explained. “In fact, it is extremely beneficial for overall health.”
Experts suggest a few practical steps to reduce light exposure at night:
Researchers also noted that many people underestimate how much light they are exposed to at night. Even dim sources such as alarm clocks, charging indicators, or light filtering in from nearby buildings can affect the body’s natural night-time processes. Over years, this low-level but constant exposure may quietly increase the risk of high blood pressure, insulin resistance, and weight gain, all of which are closely linked to heart disease. The study reinforces a growing body of evidence that sleep quality is shaped not just by how long we sleep, but by the environment we sleep in.
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