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Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.
Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.
The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:
Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.
Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.
Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.
Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.
An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.
Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.
The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.
Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.
The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.
The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.
Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:
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India is better prepared to deal with potential Hantavirus outbreaks due to the healthcare infrastructure and quarantine systems established during the COVID-19 pandemic, according to Dr NK Ganguly, former Director General of the Indian Council of Medical Research (ICMR).
In an exclusive interview with HealthandMe, Dr Ganguly said that while isolated cases of Hantavirus have appeared in India in the past, especially in crowded peri-urban and urban settings in Kerala, large-scale outbreaks have largely been reported in countries such as China, Argentina, the UK, and the US.
Dr Ganguly said that India's healthcare system significantly improved after the deadly COVID pandemic.
“India is overprepared in a way that during the COVID-19, our system, even at the district level or in much more rural settings, got established,” he said.
He pointed out that hospitals now have access to ECMO, BPAP systems, ventilators, and oxygen management facilities to curb the spread in case of an outbreak.
Dr Ganguly also mentioned the availability of antiviral drugs and experimental vaccine efforts that could potentially be explored for hantavirus treatment. “There are some crude vaccines which are made here also,” he said.
He added that India’s quarantine systems and public health drills developed during COVID-19 would also help contain future outbreaks.
“I think India will be okay because of the sheer transmission dynamics of this virus,” he said.
Hantavirus is a zoonotic disease that primarily gets transmitted through contact with infected rodents or exposure to their urine, droppings, and saliva, though rare cases of person-to-person transmission have also been reported.
According to the World Health Organization (WHO), 11 cases — including three deaths — have been confirmed so far. However, additional suspected and confirmed cases are likely to emerge across countries.
Also read: Hantavirus Can Linger Indoors, Spread Through Contaminated Dust, Says Infectious Disease Expert
The One Health approach is critical in understanding and containing outbreaks like hantavirus, Dr Ganguly said.
The One Health approach, which integrates human health, animal health, and environmental monitoring, is also crucial to target the emerging infectious diseases, he noted.
Further, the noted microbiologist stressed the importance of strengthening surveillance across humans, animals, and the environment.
He explained that disease surveillance requires collaboration between bird specialists, forest experts, environmental scientists, and mammologists, especially for tracking zoonotic infections such as avian flu and hantavirus.
“In avian flu, birds follow special migration routes, so we needed bird specialists, forest experts, environmental experts, and mammologists,” Dr Ganguly said.
The expert also highlighted the growing challenge posed by shrinking spaces between humans and animals and the role of antimicrobial resistance (AMR) in emerging disease threats.
“Animal health is equally important. We need to maintain them, track their movements, and do surveillance,” he said.
Dr Ganguly also warned that rising temperatures and shrinking boundaries between humans and animals could increase the risk of future infections.
“It is an environmental infection. With the rise of temperature, more hantavirus infections occur,” he told HealthandMe.
Calling surveillance one of the most critical tools in outbreak prevention, he urged India to strengthen monitoring systems for animals, vectors, and humans alike.
“We need to set up a dedicated surveillance for hantavirus in India, and we need to track hantavirus,” he said.
Dr Ganguly explained that to date, hantavirus cases in India have been detected accidentally during testing for respiratory infections or flu-like illnesses using advanced panel-based diagnostic systems.
“Like now these days, what happens is that when you are getting respiratory infection or flu-like symptoms, they put up a test system which is known as bio-fire or a thing like that which identifies 26 panels and gives the CT scoring of that, so from there, hantavirus emerged,” he said.
He added that India should strengthen surveillance tools and continue monitoring infections in animals, vectors, and humans alike.
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Prateek Yadav (38), the son of late Samajwadi Party founder Mulayam Singh Yadav, died due to a massive blockage in the blood vessels of the lungs, leading to a collapse of the heart and respiratory system, as revealed in the postmortem examination report.
According to the autopsy findings, the provisional cause of death was recorded as “cardiorespiratory collapse due to massive pulmonary thromboembolism.” In simple terms, doctors said a large blood clot had blocked blood flow to the lungs, causing his heart and breathing to fail.
An embolism is any object (clot, fat, air, tissue) traveling through the bloodstream that becomes stuck, blocking blood flow. A thromboembolism is a specific type of embolism where that travelling object is a piece of a blood clot (thrombus) that has broken off from its original site.
It is a life-threatening condition that happens when a blood vessel in the lungs is blocked by a blood clot.
The common symptoms may include:
The blood clot starts in a deep vein in the leg and travels to the lung in most cases. Rarely, the clot forms in a vein in another part of the body, noted Mayo Clinic. When a blood clot forms in one or more of the deep veins in the body, it is called a deep vein thrombosis or DVT.
Other symptoms of pulmonary embolism include:
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Meanwhile, Karnataka's Planning and Statistics Minister, D. Sudhakar (66), passed away after a prolonged battle with a lung infection.
The most common lung infections that people experience are pneumonia, bronchitis, tuberculosis, influenza-related infections, and severe viral illnesses.
Experts noted that these lung infections cause fluid or pus to fill the air sacs, which prevents oxygen from entering the bloodstream.
"What may initially appear as a routine cough, fever, or chest infection can progress to severe pneumonia, respiratory failure, sepsis, or permanent lung damage,” Dr. Vikas Mittal, Director - Pulmonologist, CK Birla Hospital, Delhi, told HealthandMe.
Warning signs include
Dr. Nikhil Rajvanshi, Consultant - Paediatric Pulmonology, Rainbow Hospital, Delhi, told HealthandMe that children may be more at risk of pulmonary infections as they can become dangerous quickly because their lungs and immune systems are still developing.
Common illnesses such as bronchiolitis, pneumonia, influenza, and other viral infections may rapidly lead to breathing difficulty, low oxygen levels, dehydration, and respiratory distress. Infants, premature babies, malnourished children, and those with asthma or congenital disorders are at higher risk of complications.
The experts called for
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US President Donald Trump's attempt to clarify the meaning of "sea" while discussing drug smuggling has again raised concerns of dementia.
While the 79-year-old President rambled between “sea and see” in the middle of discussing drug problems in the US, social media went rife with the rumor of his cognitive decline.
"Drugs coming by sea meaning coming by water. A lot of people don’t know what I mean by sea. They think I mean vision. I’m talking about sea like the sea," he said. He was speaking at the White House, while hosting law enforcement officials for a dinner in the Rose Garden in celebration of National Police Week.
His comments were called out by social media as his apparently worsening cognitive capabilities.
"When he says 'a lot of people' he means 'me.' His cognitive issues are a crisis," one social media user declared, while another admitted, "He’s getting worse."
Trump has spoken on sea and see, during a maternal healthcare event last week, where he also referred to himself as the “father of fertility.”
Earlier, speaking at the White House Small Business Summit, Trump said he has taken the Montreal Cognitive Assessment three times and “aced each one,” claiming a doctor told him it was the first time they had seen a perfect score, The Daily Beast reported.
The US President said he answered the test questions easily, suggesting he is cognitively in good condition—a claim that critics have repeatedly questioned.
“The first question is very easy,” he said. “You have a lion, a bear, an alligator, and a—what’s another good…? A squirrel. Which is the squirrel?” He added that the difficulty increases as the test progresses. “By the time you get to the middle, they’re very tough.”
However, the test’s creator, Canadian neurologist Ziad Nasreddine, has challenged Trump’s claims. “It wasn’t designed to be a test of IQ,” he told nine.com.au. “It was designed to assess normal cognitive performance.”
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A group of medical experts, including neurologists, psychiatrists, and other physicians, has sounded the alarm over what they’ve described as Trump’s deteriorating mental health.
The experts have not specifically examined Trump face-to-face. But, they analyzed Trump's statements and behaviors over the past year, and stated that he’s “mentally unfit” and must be removed from office “with the greatest urgency” amid the escalating tension around the world, according to their statement published in The BMJ.
“It is our professional opinion that they (Trump's statements) reflect a rapidly worsening, reality-untethered, increasingly dangerous decline,” the experts said.
They also listed some of Trump’s observable serious medical issues, such as “Marked deterioration in cognitive functioning, evidenced by disorganized and tangential speech, rambling digressions, factual confusions, unexplained sudden changes of course in strategic matters, both national and international, episodes of apparent somnolence during critical public proceedings.”
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What The White House Says
The White House has continued to say that Trump remains in strong health.
In October 2025, White House physician Captain Sean Barbabella said the president “continues to demonstrate excellent overall health,” AOl.com reported.
"President Trump’s sharpness, unmatched energy, and historic accessibility stand in stark contrast to what we saw during the last administration when Democrats and other lunatics intentionally covered up Joe Biden’s serious mental and physical decline from the American people,” White House spokesman Davis Ingle was quoted as saying to The Daily Beast.
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