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Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.
Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.
The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:
Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.
Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.
Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.
Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.
An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.
Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.
The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.
Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.
The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.
The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.
Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:
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A 47-year-old autorickshaw driver from Royapettah, who had received a full course of vaccination after being bitten by a stray dog in July 2025, died of rabies at the Rajiv Gandhi Government General Hospital (RGGGH). He is the 22nd person to succumb to the disease in Tamil Nadu this year.
His death has left experts asking a difficult question, if protocols were followed, why are people still dying? Public health specialists suggest this may not just be a failure of administration, but a sign that India’s long-standing rabies protocol itself needs re-examination.
“Rabies infects mammals, including dogs, cats, livestock and wildlife. It spreads to people through saliva, usually by bites, scratches, or direct contact with mucous membranes such as the eyes, mouth, or open wounds. Once symptoms appear, rabies is virtually 100% fatal,” explains Dr. Surrinder Kumar, MBBS, General Physician.
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For those unversed, Rabies immunoglobulin is a medication made up of antibodies against the rabies virus. It is used to prevent rabies following exposure.
According to Dr Surrinder, the main reasons are:
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Alongside immunoglobulin, at least five separate rabies vaccine doses are necessary. These, Dr. Shaswath says, are not without side effects, as “every time people take the vaccine, they get fever.” While cities are able to conduct mass vaccination campaigns, rural areas face significant challenges in this regard.
He further stresses that rabies is not confined to dog bites alone. The virus can also spread from other animals, and in rare cases even from humans, if infected saliva comes in contact with open wounds or mucous membranes. “A bite isn’t always necessary,” he warns.
Dr. Ranjeet Singh, Professor and Head of General Medicine at NIIMS Medical College and Hospital, echoes the same concerns. He emphasises that rabies deaths in India do not reflect a failure of the vaccine itself. Instead, the main reasons are late treatment, lack of awareness, incomplete vaccination, shortage of immunoglobulin, and limited access in rural areas.
India follows the WHO-approved five-dose rabies vaccine protocol, with immunoglobulin recommended for severe (Category III) bites. But the bigger question, they say, is whether the protocol assumes ideal conditions, which is immediate wound washing, uninterrupted cold chain storage, and trained professionals administering injections at the wound site. In reality, these conditions are not always met.
To end rabies deaths in India, awareness must go hand in hand with medical access. Every bite, no matter how small, needs immediate action: wash, vaccinate, and if severe, take immunoglobulin.
“Rabies is 100% preventable but 100% fatal if ignored. No bite should ever be taken lightly. The key is simple, wash, vaccinate, and complete the course,” concludes Dr. Surrinder Kumar.
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Sometimes a simple headache can derail your entire day. It slows down your work, causes you issues etc. When that happens, the easiest way to get rid of it is by taking medicine. However, did you know, you may be able to avoid taking the medicine by doing a simple check before?
Sometimes, the cause isn't a lack of medicine—it's a lack of hydration. Dehydration is a very common cause of headaches, and it's often overlooked. In a post, Suzanne Soliman, a US board certified pharmacist, explained that your headache may be a simple issue, that may not need medicine. Before you grab a pain reliever, try this simple trick: Drink a full glass of water with a small pinch of salt. The salt helps your body absorb the water better.
But how does salt water help you get rid of headaches? Is there medical backing to this or is it a placebo trick that helps some people?
For some people, drinking salt water can help relieve a migraine, but it depends on the cause. Here are a couple of reasons why it might work:
If you've been sweating a lot, you lose both water and salt. Rehydrating with a glass of water and a pinch of salt can restore your body's balance and ease the headache.
Several studies, like a 2021 study published in the Medical Science journal, suggest that if your body is used to a high-salt diet (like the average American diet), suddenly reducing your sodium intake can trigger a "withdrawal" headache. In this case, eating or drinking something salty might help.
However, the evidence isn't clear, and drinking too much salt water can make you feel sick. If you want to try this, only add a tiny pinch of salt to a full glass of water. A better way to get more salt might be through salty snacks or a sports drink with electrolytes.,
There's a complex link between salt and migraines. Some people who eat a lot of salt regularly report fewer migraine symptoms, possibly because their bodies are used to a high-sodium diet.
According to the 2021 study, the relief people feel when they eat salty foods during a migraine isn't a cure, but rather a temporary relief from withdrawal symptoms. This might help explain why some studies have found that people who eat more salt tend to have fewer migraines—their bodies are simply getting the high amount of salt they're used to.
On the other hand, consuming too much salt can also be a migraine trigger. Eating too much salt can increase your blood pressure, which is a known cause of headaches and migraines. Studies have shown that for some people, a high-salt diet can actually make a migraine episode last longer.
Also Read: Frank Grillo On Steroid Use: 'I’m Not Cheating At Anything Except Aging'
A 2023 study published in JAMA included 213 people with a median age of 61. The group was 65% female and 64% Black. Each person followed three different diets: their usual diet, a high-salt diet, and a low-salt diet.
If your headaches are related to high blood pressure, a low-salt diet may be more beneficial
Salt's effect on migraines is different for everyone. It might help if your headache is caused by dehydration or a sudden drop in sodium, but it could also trigger a migraine or make it worse if you have high blood pressure or are sensitive to salt. Always talk to your doctor to figure out what's best for you and your symptoms.
Salt's effect on migraines is different for everyone. It might help if your headache is caused by dehydration or a sudden drop in sodium, but it could also trigger a migraine or make it worse if you have high blood pressure or are sensitive to salt. Always talk to your doctor to figure out what's best for you and your symptoms.
(Credit- Frank Grillo Instagram)
Frank Grillo, the 60-year-old actor known for his roles in superhero films like Superman Peacemaker, recently opened up about how he gets in shape for the big screen. In a recent interview on the Men’s Health “Strong Talk” podcast, he candidly discussed his use of steroids, revealing that many actors use similar methods to prepare for roles.
Grillo spoke on his use of the steroid medication, and gave his view on its criticism. As a part of his Testosterone Replacement Therapy treatment, which helps improve symptoms of low testosterone, he took the medication, and it helped him deal with many age-related health issues.
Grillo shared that about six years ago, he found out his natural testosterone levels were low. To fix this, he started using testosterone replacement therapy. He says this treatment has helped him in many ways, like improving his sleep, speeding up his recovery after workouts, and making him feel happier in general. Grillo doesn't hide his use of steroids.
Also Read: Do This 1 Thing Before You Pop A Pill For Your Headache According To Pharmacist
He pushes back against people who call it “cheating,” arguing that as an actor, he isn’t competing in a sport like football or wrestling. Instead, he’s simply trying to look the part for a movie role and, in his words, is "not cheating at anything except aging." He also points out that when actors are hired for a superhero movie, there’s an expectation to look a certain way, and sometimes that means using medications like Anavar, a steroid that acts like testosterone.
Grillo claims that what he's doing is not uncommon in Hollywood. He believes that many other actors also use steroids to quickly achieve dramatic body transformations for their roles. He mentioned that drugs like Anavar and Deca, which is another type of steroid, are now often prescribed by doctors, which means their use can be monitored by a medical professional.
Grillo was very clear that incredibly muscular bodies aren't natural. He explains that it's just not realistic for someone to look one way for most of the year and then suddenly gain 35 pounds of muscle. He says that while many actors might not want to talk about it, everyone in the industry knows exactly what’s going on.
According to US National Cancer Institute, Oxandrolone is a man-made drug that's very similar to testosterone, a natural hormone in our bodies. It works by attaching to and activating certain receptors, which are like tiny switches in our cells. Because of this, oxandrolone is used for several reasons, including:
Testosterone replacement therapy: To help men who have low testosterone levels.
HIV-wasting syndrome: To help people with HIV who are losing a lot of weight and muscle.
Other conditions: To help the body hold onto more nitrogen (which is key for building muscle) and to increase lean muscle mass.
According to Hospital for Special Surgery (HSS), as men get older, it's common for them to experience a natural decline in both testosterone and muscle mass. While this is a normal part of aging, there are ways to fight back against it.
Testosterone is a crucial hormone for men. It helps build muscle by creating proteins, which in turn increases muscle strength. Starting around age 40, a man's testosterone levels gradually drop by about 1-2% each year. This decline can lead to symptoms like fatigue, hair loss, and depression, but many men don't realize what's causing these changes because testosterone levels aren't always checked during a routine doctor's visit.
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