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Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.
Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.
The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:
Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.
Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.
Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.
Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.
An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.
Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.
The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.
Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.
The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.
The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.
Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:
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Actor Claire Foy has revealed that a long, uncomfortable health struggle picked up while travelling ended up reshaping her relationship with caffeine. The Crown star, 41, said she gave up tea and coffee after discovering she had stomach parasites, an experience she described as “gross” and “absolutely rank.”
Foy shared the story during her appearance on The Table Manners Podcast with hosts Jessie and Lennie Ware on February 4, where the conversation moved from food to a period of unexplained weight loss and constant hunger.
“I kept losing weight, and I didn’t know what was going on,” she told the hosts. Despite eating regularly, she said she never felt full. “I was so hungry,” Foy recalled, adding that the situation left her confused and worried.
The actor explained that the cause was eventually traced back to stomach parasites she had picked up while travelling in Morocco. The diagnosis came after medical tests, including stool samples, which she candidly described as unpleasant but necessary.
According to Foy, doctors told her she had been carrying the parasites for around five years, a length of time she herself described as “quite a long time.” While she did not name the specific parasites, she shared one detail that stuck with her. “They travel as a pair, I got told by the doctor,” she said, reacting with visible disgust even years later.
Living with the condition took a toll on her body and routine. The ongoing symptoms pushed her to rethink how she approached treatment and daily habits, including what she consumed.
Read: 10 Signs You May Have A Parasite
It was during treatment that Foy made the decision to give up caffeine entirely. She explained that she wanted to avoid very strong antibiotics if possible and instead followed a strict diet alongside other treatments. “I basically had to go on this diet,” she said. “I didn’t want to take really hardcore antibiotics.”
As part of that process, caffeine was cut out. “I took all this gross stuff and part of that was giving up caffeine,” Foy told the hosts. At the time, it was a major shift. She admitted she had been a heavy caffeine consumer, drinking around 15 cups of tea a day along with two coffees she had carefully planned into her schedule.
Giving up caffeine was not easy, but once she did, Foy decided to stick with it. “Once you’ve given it up, it’s such a mission to give it up, that I was like, well, maybe I’ll just give it a go,” she said.
Now fully caffeine-free, she even brought her own tea bags to the podcast recording. The show is known for hosts and guests sharing food and drinks in the Ware family kitchen, making her preparation a small but telling detail of how seriously she takes the change.
Medical experts note that parasitic infections usually require medication to clear completely, often involving antiparasitic drugs and sometimes antibiotics or antifungals. In many cases, a combination of treatments is needed.
Credits: Lisa Ray Instagram and BBC screengrab
"I went into chemo-induced menopause at 37," said Lisa Ray, a Canadian actress during an interview with BBC. She also shared the clip of the interview on her Instagram account talking about the importance of awareness about the side effects of cancer and its treatment on women. Sharing the clip on her Instagram story, she wrote "This is me in menopause. Menopause does not have one face...I went into premature chemo-induced menopause at 37."
She revealed that she had blood cancer, called Multiple Myeloma. "At that time, it was the least of my worries. I had a blood cancer called Multiple Myeloma to contend with… But after recovering, I could focus on what being in menopause suddenly at 37 would mean. And I had no one to talk to," said Lisa, now 53.
Chemotherapy do not just target cancer cells, but it can also harm healthy cells, which are fast diving. Ovaries fall into that category and thus they stop producing hormones like estrogen and progesterone, which pushes the body into sudden menopause.
This condition is called iatrogenic menopause or chemotherapy-induced ovarian failure. While it could be temporary for some people, for others, it could be permanent. Experts explain that women under 30 could see their periods return after the treatment.
Chemotherapy works by attacking cells that grow and divide rapidly. While this helps destroy cancer cells, it also affects healthy cells, such as those responsible for hair growth, which is why hair loss is a common side effect.
This process can also impact reproductive organs, including the ovaries, and disrupt hormone production. As a result, levels of estrogen and progesterone—the key hormones involved in menopause—may become imbalanced due to chemotherapy’s effects on the endocrine system.
Damage to cells and these hormonal shifts can trigger menopausal symptoms and, in some cases, cause periods to stop altogether.
For people over 40, hormone levels may already be naturally declining. In such cases, chemotherapy can accelerate a menopausal transition that has already begun.
The symptoms are same as one experiences in natural menopause, which include:
However, Lisa also points out the emotional impact, which could be intense especially for someone who is young and was not expecting to face menopause for decades. “Both menopause and disease-induced menopause have been treated with shame and silence for too long,” Lisa wrote on her Instagram post.
Hormone Replacement Therapy (HRT): When considered safe and not restricted by hormone-sensitive cancers, HRT can help manage symptoms while supporting bone strength and heart health.
Non-hormonal treatments: Certain medications, including SSRIs, SNRIs, and gabapentin, may reduce hot flashes, while vaginal moisturizers and lubricants can relieve dryness.
Lifestyle changes: Staying physically active, following a calcium and vitamin D-rich diet, maintaining a healthy weight, and managing stress can significantly support overall wellbeing.
Fertility support: Options such as egg or embryo freezing before treatment, along with consultations with a fertility specialist afterward, may help preserve future parenthood possibilities.
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Long winters and lack of sunlight has renewed attention on vitamin D deficiency, a condition closely linked to bone health and overall well-being. Health data show that the problem is far more widespread than many realize, with potential consequences that range from brittle bones to mood changes.
Vitamin D plays a crucial role in helping the body absorb calcium, an essential mineral for strong bones and teeth. Without enough vitamin D, calcium absorption drops, weakening bone structure over time. This increases the risk of fractures, particularly among older adults.
Beyond bone metabolism, vitamin D also supports muscle function and contributes to a healthy immune response. Researchers have also explored its influence on mental well-being, as vitamin D receptors are present in several areas of the brain.
According to figures from the Robert Koch Institute, around 30 percent of adults in Germany have insufficient vitamin D levels. This is striking, given that the vitamin is produced by the body when skin is exposed to sunlight.
Experts point to modern lifestyles as a key reason. Many people spend most of their day indoors, often working in offices with little exposure to natural light. Seasonal factors also play a role, as sunlight is weaker and less frequent during autumn and winter months. In such conditions, relying on sunlight alone is often not enough to maintain healthy vitamin D levels.
Food can support vitamin D intake, although it usually provides smaller amounts compared to sunlight. Fatty fish are among the best dietary sources. Salmon, herring, eel, tuna, and pike perch contain relatively high levels of the vitamin and are often recommended for people at risk of deficiency.
Other animal-based options include eggs, liver, beef, and butter. For those who avoid animal products, plant-based sources can contribute modest amounts. Mushrooms, spinach, kale, broccoli, and Brussels sprouts are commonly mentioned. Some fruits such as avocados, kiwis, oranges, bananas, and figs are also included in vitamin D-friendly diets, though their contribution is limited.
Read: Vitamin D Supplements Under Scrutiny As It Fails Safety Test
Because many of these foods are eaten infrequently, especially fish, diet alone often fails to correct a deficiency.
Vitamin D deficiency can show up in different ways. Many people report persistent fatigue, low mood, or depressive symptoms. While studies support a connection, researchers note that the exact biological pathways are still being studied.
Physical signs are often related to bone health. Weakened bones can increase the risk of fractures and cause general bone pain. Digestive issues and reduced tolerance to certain foods have also been reported in some cases. A deficiency is usually confirmed through a blood test ordered by a doctor.
While deficiency is common, excessive vitamin D intake can also pose risks. Health experts stress that overdoses do not occur through sunlight or normal diets, but through high-dose supplements taken over time.
Too much vitamin D can raise calcium levels in the blood, a condition known as hypercalcemia. This may lead to kidney damage, heart rhythm problems, and calcification of blood vessels. Individual risk varies depending on factors such as body weight, metabolism, and alcohol consumption, making medical guidance essential before supplement use.
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