Your body hosts trillions of bacteria, viruses, and fungi, collectively known as the microbiome. While some bacteria are linked to disease, many play essential roles in supporting your immune system, heart health, weight management, and overall well-being. This article delves into the significance of the gut microbiome and its impact on health.

What Is Gut Microbiome?

Interestingly, bacterial cells outnumber human cells in the body, with approximately 40 trillion bacterial cells compared to 30 trillion human cells. With up to 1,000 species of bacteria present in the gut, each plays a distinct role. While most bacteria contribute positively to health, some can be harmful. Together, these microbes weigh around 1–2 kilograms, functioning almost like an additional organ essential for overall well-being.

How Does Gut Microbiome Influence Your Health?

The relationship between humans and microbes has evolved over millions of years, with the gut microbiome playing a crucial role from birth. Initial exposure to microbes occurs during birth, and some evidence suggests that exposure begins in the womb. As the microbiome diversifies, it starts influencing key bodily functions:

Digestion of breast milk: Beneficial bacteria like Bifidobacteria help break down essential sugars in breast milk, supporting infant growth.

Fiber digestion: Some bacteria process fiber into short-chain fatty acids, which contribute to gut health and reduce risks of obesity, diabetes, and heart disease.

Immune system regulation: The gut microbiome interacts with immune cells, influencing how the body responds to infections.

Brain health: Emerging research suggests a link between the gut microbiome and brain function, potentially affecting mental health and neurological processes.

Gut Microbiome And Weight Management

An imbalance between beneficial and harmful microbes, known as gut dysbiosis, may contribute to weight gain. Studies on identical twins—one with obesity and the other without—suggest that microbiome composition plays a role in body weight independent of genetics. Additionally, animal studies indicate that gut bacteria can influence weight gain, even when calorie intake remains constant.

Probiotics, beneficial bacteria found in supplements and certain foods, can help restore gut balance and support weight loss, though their effects may be modest.

Gut Health And Disease Prevention

The gut microbiome plays a vital role in preventing and managing conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Imbalances in gut bacteria may lead to bloating, cramps, and digestive issues. On the other hand, beneficial bacteria like Bifidobacteria and Lactobacilli help strengthen the intestinal lining, reducing the risk of gut-related disorders.

Impact On Heart Health

Research suggests that the gut microbiome influences heart health by affecting cholesterol levels and blood pressure. Certain harmful bacteria produce trimethylamine N-oxide (TMAO), a compound linked to blocked arteries and heart disease. However, probiotics, particularly those containing Lactobacilli, may help reduce cholesterol levels and promote cardiovascular health.

Blood Sugar Regulation And Diabetes Risk

The gut microbiome also plays a role in regulating blood sugar levels. Research on infants genetically predisposed to type 1 diabetes indicates that gut microbiome diversity declines before disease onset. Furthermore, individual variations in gut bacteria may explain why people experience different blood sugar responses to the same foods.

Connection Between Gut And Brain

The gut is physically connected to the brain through nerves, and certain bacteria help produce neurotransmitters like serotonin, which influence mood and mental health. Studies indicate that people with mental health disorders often have different gut bacteria compared to those without such conditions. Additionally, some probiotics have shown promise in alleviating symptoms of depression and anxiety.

Tips For Healthier Gut Microbiome

Maintaining a balanced gut microbiome is crucial for overall health. Here are some strategies to support gut health:

• Eat a diverse range of foods: A varied diet rich in fiber, legumes, and fruits promotes microbial diversity.
• Consume fermented foods: Yogurt, kefir, and sauerkraut contain probiotics that enhance gut health.
• Limit artificial sweeteners: Some artificial sweeteners can encourage the growth of harmful bacteria.
• Include prebiotic foods: Bananas, oats, and asparagus contain fibers that nourish beneficial bacteria.
• Breastfeed infants when possible: Breastfeeding promotes a healthier gut microbiome in babies.
• Choose whole grains: Whole grains contain fiber and beneficial compounds that support digestive health.
• Opt for a plant-based diet: Vegetarian diets may reduce inflammation and support a healthier gut microbiome.
• Consume polyphenol-rich foods: Green tea, dark chocolate, and olive oil contain compounds that foster beneficial bacteria.
• Take probiotics if needed: Probiotic supplements can help restore gut balance after disruptions, such as antibiotic use.
• Use antibiotics cautiously: While antibiotics can be life-saving, overuse can harm beneficial gut bacteria.

A globally introduced, newer-generation cataract lens was used in India for the first time, enhancing patient’s recovery journey and treatment outcome

Since her diabetes diagnosis 5 months ago, Mrs Vani Vaish had done what doctors tell every diabetic to do - turn up regularly for an eye exam because diabetes can quietly damage the blood vessels and nerves in your eyes. The eye damage often gives no major noticeable warning until real damage has been done, which is exactly why the screening isn't optional, symptoms or not.

How A Routine Eye Check-Up Revealed A Cataract

During one of these routine visits, Mrs Ahuja complained of blurring in her vision and increasing glare around headlights and streetlamps at night. Her ophthalmologist identified a cataract. For people living with diabetes, regular eye examinations can be important for more than monitoring diabetic retinopathy, as diabetes can also increase the risk of developing cataracts and may lead to their occurrence at a younger age.

The treatment options were discussed with her in detail, including the potential benefits and limitations of the technology, individual variations in outcomes and the considerations involved in selecting a presbyopia-correcting lens. Following a detailed evaluation, Mrs Ahuja underwent cataract surgery with implantation of the Clareon PanOptix Pro, a newer-generation trifocal intraocular lens that had recently become available in India.

Also read: What Is Lutein? The Eye-Friendly Antioxidant You Crave—Yet Don’t Know About

What The Newer-Generation Lens Is Designed To Do

The significance of the technology lies in what it is designed to change in cataract vision correction. Trifocal lenses split incoming light to provide vision across near, intermediate and distance ranges. The newer-generation optical design used in PanOptix Pro is intended to use available light more efficiently and reduce light scatter — an advancement that aims to support better quality of vision across different distances while addressing some of the visual compromises associated with multifocal lens technology.

Because no two patients have the same visual demands, expanding access to newer technologies plays a critical role in modern care. Our role is to evaluate each patient’s unique needs and ensure that the most suitable and advanced treatments available actually reach the patient, giving them every opportunity for a better quality of life.

The procedure marked the first use in India of the globally introduced Clareon PanOptix Pro lens. For MRs Vaish, the outcome of the treatment has matched what she hoped for. She reports clear vision and no floaters or other visual disturbances. Her recovery has also been smooth, and she has not even needed the temporary protective glasses in the days following the procedure.

Why Regular Eye Exams Matter For People With Diabetes

Her case highlights two important aspects of modern eye care. Regular eye examinations are important especially for people living with diabetes. A routine screening intended to monitor retinal health can also help identify other conditions affecting vision, including cataracts.

It also demonstrates that access to advanced medical technologies can significantly expand treatment possibilities and enhance the patient's recovery journey. When newer innovations are combined with careful clinical evaluation and personalised decision-making, they can help doctors move beyond a one-size-fits-all approach to treatment and offer patients options better suited to their individual visual needs and lifestyles.

By Dr Sudipto Pakrasi, Chairman, Ophthalmology, Medanta Mediclinic Defence Colony

Major sporting events such as the IPL, FIFA World Cup, Olympics and Asian Games have become powerful platforms for brands to promote unhealthy products through sponsorships, endorsements and social media.

In an exclusive interview with HealthandMe, Dr. Robin Ireland, public health activist and honorary research fellow at the University of Glasgow, UK, discussed how the commercialization of sport has helped normalize junk food, sugary drinks and alcohol, and its impact on children “who may not always recognize the difference between advertising and fact”.

“It's an awful lot healthier to play sport than to watch it, because sport is now associated with junk food, sugary drinks and alcohol,” he said.

Excerpts from the interview

Q: How does unhealthy-product marketing in sport affect children? And do “zero sugar” or “alcohol-free” labels change that?

Dr. Robin: I think it has a huge impact. Worldwide, we're seeing major problems with overweight and obesity from a very early age, as well as type 2 diabetes. Many causes of cancer and heart disease are preventable through healthier lifestyles, yet we're constantly being promoted things that aren't good for us.

Alcohol companies often promote alcohol-free products. In India, I'm aware of surrogate marketing, where alcohol companies produce packaged drinking water using the same brand, colourway and distribution networks. So it's hardly surprising these brands are normalised to young people. Even where alcohol advertising is banned, alcohol can still be heavily promoted.

A lot of this comes down to what we eat, but very specifically what we drink — alcohol, sugary drinks and now energy drinks. For most of us, we're much better off drinking water.

Q: Does elite sport give sugary drinks, fast food and alcohol a “health halo”?

Dr. Robin: Sport presents glamour and excitement, and children look up to big performers and superstars who often promote products they probably don't consume themselves because they're not good for sporting performance. Yet their names and images are used to create that excitement and, as you described, a health halo.

Brands want to be associated with that healthy image. Athletes think that if they want to perform like a Sachin Tendulkar or another superstar, they need a sports drink or energy drink. And of course, they don't. But that's what the brands are trying to do.

Also read: Exclusive: GLP-1 Drugs Are The ‘New Statins’, Says University Hospital Birmingham Professor

Q: Cristiano Ronaldo famously pushed away a soft drink and asked for water. Where should athletes and sports bodies draw the line on unhealthy-product sponsorships?

Dr. Robin: It was one of those iconic moments, wasn't it, where he pushed the sponsored bottle away and said, “Agua.” The line is difficult for sportspeople. I don't necessarily want to blame them. It's the rules set by the governing bodies. I've just looked up the IPL sponsors, and you immediately find cola brands across the teams and on shirt branding. It's everywhere.

So it's hard to criticise individual athletes. Some earn huge sums of money, so perhaps it would be nice if one or two took the Ronaldo position. There are also athletes who, because of their religion, will not drink alcohol or associate themselves with alcohol products.

But I think it's the governing bodies. How have we allowed this to happen? This deluge of sugary drinks at a time when we have high levels of type 2 diabetes and children living with overweight and obesity. It's really wrong.

Q: What can sport learn from the ban on tobacco advertising when regulating alcohol, sugary drinks and ultra-processed foods?

Dr. Robin: The short answer is I believe yes, but I think we're quite a long way from that. I grew up with tobacco advertising all over the place, particularly in cricket and F1. I remember F1 saying, “We're not going to be able to survive without tobacco advertising.” They were basically mobile tobacco packet ads with Marlboro ads on the cars going past; it was completely absurd. And we've got rid of it.

That was partly through the World Health Organization Framework Convention on Tobacco Control. We simply have to take these things much more seriously.

I get very cross with people who say we couldn't survive without this. I love sport, but I think we probably could. Across pretty much all sport, there is a lot of money coming in from other places. We don't have to be dependent on junk food and alcohol. It's completely inappropriate.

Read More: High Sugar, Salt Or Fat? India May Mandate Red Hexagon Labels On Food Packs

Q: Are food labels enough, or should sports advertising also be restricted?

Dr. Robin: Labelling helps, but it's only part of the solution. Not everybody has the time or resources to read labels, and people will still buy what they can afford and what is accessible.

In the UK, we've had some advertising controls, but as we saw with tobacco, sport does its own thing. Sport seems to be allowed a free ride.

In India and the UK, sport is huge, and politicians are in love with it. Advertising, particularly for junk food, is everywhere. Sport will find a way around restrictions unless it's specifically mentioned. In India, you're not allowed to have alcohol advertising, but sport seems to have found a way around it.

We need to take regulation more seriously and recognise that people will find ways around it. It has to be robust to work.

Q: What would effective regulation of unhealthy-product marketing in sport look like?

Dr. Robin: We could be talking about that a long time, so let's come up with one or two manageable measures. I don't think sugary drinks companies or alcohol should be named in event titles. I also don't think brands should appear on the front of shirts or uniforms.

You can also have rules around advertising when events are broadcast. In the UK, we've taken steps around gambling. In the English Premier League, gambling brands have been removed from the front of shirts, and gambling ads can't be shown during the advertising break in the middle of games. It's a limited move, but it's a start.

The IPL has a cola sponsor and a packaged drinking water sponsor that happens to be an alcohol brand. We need to get away from that. It's inappropriate. The Asian Games, interestingly, has 62 sponsors. As far as I can tell, only one is particularly unhealthy, and I'd rather they weren't there either, because it's an official hydration partner that is yet again a sugary drink. But it shows there are people willing to support sport outside these industries, and we perhaps need to look at them more.

For many Indians, especially those with busy work schedules, a morning cup of tea or coffee has become a daily necessity. From a quick cup before heading to work to coffee breaks during long office hours, caffeine is now a regular part of urban routines. But this habit may have implications for digestive health.

For most healthy people, moderate coffee consumption can be part of a normal diet. In some individuals, however, it may lead to symptoms like heartburn, acidity, abdominal discomfort, bloating, or an increased urge to pass stools.

Coffee can affect the digestive system in multiple ways. It is known to stimulate the secretion of gastric acid and increase movement in the colon. This is why some people feel the need to use the toilet shortly after having coffee. The intensity of these effects varies from person to person.

The link between coffee and gastroesophageal reflux disease, or GERD, is often discussed. Coffee may worsen reflux symptoms in certain people, although research findings have not been entirely consistent. A 2026 systematic review and meta-analysis involving over 122,000 people found a small statistical increase in GERD among coffee drinkers, but the clinical significance of this association is still considered uncertain.

This suggests that not everyone with acidity needs to stop drinking coffee altogether. It is more important to observe whether coffee consistently triggers symptoms. Factors such as the quantity consumed, the timing of consumption, individual sensitivity, and what is added to the drink can all play a role.

In India, people often drink coffee with generous amounts of sugar, milk, or cream. For some people, these additions may contribute to digestive discomfort. Drinking several cups a day can also increase overall caffeine intake, which may aggravate symptoms in sensitive individuals.

Rather than blaming coffee entirely for digestive issues, it helps to identify individual triggers. If coffee repeatedly causes heartburn or other discomfort, it may be sensible to reduce intake and consult a gastroenterologist for guidance.

The stimulating effect of coffee on intestinal movement, which leads to a bowel movement soon after the morning cup for some, is not necessarily a sign of an unhealthy gut.

However, persistent symptoms such as frequent heartburn, difficulty in swallowing, repeated vomiting, unexplained weight loss, ongoing abdominal pain, or a significant change in bowel habits should not be attributed to coffee alone and require proper medical evaluation.

Dr. Pradipta Kumar Sethy, Director, Gastroenterology, Manipal Hospitals, EM Bypass and Mukundapur