Metabolism plays a big role in our health, it’s not just about helping your digestive system work smoothly, but the way your body breaks down the food and helps nutrients get absorbed into the body that matters. But often due to one reason or the other, your metabolism can slow down, which then causes issues with people. Many people think that the reason they may be gaining weight could be because of their poor metabolism, so how does one go about fixing this issue and how do you even know that the fault lies with your metabolism.

To understand why your metabolism may be slowing down, we must understand what role it exactly plays. Metabolism is the process your body uses to turn food into energy. It's essential for everything from breathing and digestion to keeping you warm. Several things affect how fast your metabolism works, including your genes, health, and lifestyle. A slow metabolism means your body burns fewer calories, which can lead to tiredness, dry skin, weight gain, and cravings.

Why Does Your Metabolism Slow Down?

There can be many reasons why your metabolism may be slowing down. You inherit some of it, and it tends to slow down as you age, often due to changes in your body and less muscle. Men and women have different metabolisms because of body size, makeup, and hormones. What you eat matters too – not enough healthy food or a very low-calorie or high-fat diet can slow it down. A lazy lifestyle, lack of sleep, and stress can also make your metabolism sluggish. Certain health problems like diabetes or an underactive thyroid, and even environmental factors, may also play a role.

Signs You Need To Improve Your Metabolism

While these are some common signs, it is best to visit a healthcare professional and ask for their opinions before you try a solution. There are many underlying reasons as to why you are experiencing slow metabolism, it can also be a side-effect of some medicine. A healthy lifestyle goes a long way, especially for people who already have digestive issues, kidney or even mental health issues like stress and anxiety.

Constant Fatigue

Feeling tired all the time, even without a good reason, could mean your metabolism is slow. A slow metabolism means your body breaks down food into energy slowly, leaving you with low energy levels. You might feel sluggish or get tired easily throughout the day. Changes in what you eat or your body composition (how much fat and muscle you have) can also make you feel more tired.

Dry Skin

Dry skin is common in winter, but if you have it all the time, it could be a sign of a slow metabolism. Thyroid hormones help control your metabolism and also keep your skin hydrated. If your thyroid isn't working right and your metabolism is slow, your skin might get very dry.

Weight Gain

If you're eating healthy and exercising but still gaining weight, a slow metabolism could be the problem. A slow metabolism doesn't turn food into energy quickly, so you burn fewer calories. Extra calories are stored as fat, making it hard to lose weight.

Feeling Cold

Feeling cold even when it's not cold outside can be a sign of a slow metabolism. Your body generates heat through metabolism. If your metabolism is slow, your body temperature might be lower. Some studies show that people with an underactive thyroid or obesity may have lower body temperatures because of a slow metabolism. This can be because of problems with thyroid hormones, which help your body make heat.

Food Cravings

Craving sugary or fatty foods can be a sign of a slow metabolism. Studies show that cravings are related to metabolic health. This is especially true for people who don't eat enough healthy foods, have bad eating habits, or have low muscle mass and high fat mass. Cravings might also mean your body isn't getting enough energy from the food you eat, so it wants more energy.

Mood Swings

Everyone has mood swings sometimes. But if you have them often, it could be from a slow metabolism. Low energy and hormone problems that come with a slow metabolism can make you irritable and frustrated. Some older research also suggests a link between mental health issues and a slow metabolism.

Digestive Problems

Digestion and metabolism are connected. Digestion breaks down food, and metabolism turns it into energy. If your metabolism changes, like slowing down, it can affect your digestion. A slow metabolism can cause constipation, bloating, or diarrhea.

March is the month of colon cancer awareness and with the recent cases of colon cancer patients who are younger than 50. With the death of 48-year-old actor James Van Der Beek due to colorectal cancer, concerns are rising. While cancer death rates overall in people younger than 50may have dropped by 44% since 1990, colorectal cancer has become the leading cause of cancer death in people under 50.

Can Karlyle Morris, section chief for colorectal cancer at MD Anderson Center in Houston tells NBC News, "We anticipate that this is going to be a continued trend."

What Is Colon Cancer?

Colon (colorectal) cancer begins when small growths called polyps form on the inner lining of the colon or rectum. Over time, changes in the DNA of these cells can cause the polyps to become cancerous.

As abnormal cells multiply, they replace healthy cells and eventually form a mass known as a tumor. This process develops slowly, often taking up to ten years for a precancerous polyp to turn into cancer and begin showing symptoms.

Colon cancer poses serious health risks because cancerous cells can invade healthy tissues. Over time, they may break away and spread to other parts of the body, making detection more difficult since the symptoms can resemble other conditions.

What Is The Right Age To Get Colonoscopy?

A colonoscopy is a 15 to 60 minute medical procedure that is used to examine the entire inner lining of the large intestine, which includes rectum and colon for abnormalities, such as polyps, inflammation, or cancer. A doctor uses a colonoscope, which is a thin, flexible tube with a camera to take images, remove polyps, or take issue samples.

Most health experts, including federal guidelines and the American Cancer Society, recommend that people at average risk for colorectal cancer start screening at age 45. This usually means getting a colonoscopy once every 10 years, or opting for stool-based tests every one to three years. These guidelines also play a role in whether insurance companies cover the tests.

Even so, most cases of colon cancer are still diagnosed in people over 50. What’s worrying, though, is the steady rise in cases among younger adults in their 20s, 30s and 40s over the past few decades.

Why Does Screening Begin At 45?

Colon cancer typically develops slowly. It often starts as small growths in the colon called polyps, which can eventually turn cancerous if not detected early.

In recent years, growing evidence has pushed experts to reconsider when screening should begin. In 2021, the U.S. Preventive Services Task Force lowered the recommended screening age from 50 to 45. The American Cancer Society had already made a similar recommendation back in 2018.

At the time, the change was not universally accepted. Some in the medical community felt 45 was still too young. Even today, there is ongoing debate.

Setting screening guidelines is not as simple as picking an age. Experts have to weigh the benefits of early detection against potential downsides, including costs, risks from procedures and even practical concerns like taking time off work.

The numbers also tell an important story. For people aged 40 to 44, the risk of colorectal cancer is about 21 cases per 100,000 individuals. That risk more than doubles to 47 per 100,000 between ages 45 and 49, which is one of the reasons screening begins at that point.

Still, younger adults account for a relatively small proportion of cases overall. According to the Mayo Clinic, about 10 percent of colorectal cancer cases occur in people under 50.

The Challenge Of Resources And Awareness

Another key factor is access. There are only so many specialists available to perform colonoscopies, and even now, people can wait months for an appointment.

On top of that, screening rates among younger eligible adults remain low. Only about one in five people aged 44 to 49 are up to date with recommended screenings.

Experts say that if the screening age were lowered further, participation might drop even more. For now, the focus remains on improving awareness and encouraging those already eligible to get screened on time.

For most parents, the toddler years are filled with first words, wobbly steps and dreams of the future. For Gus and Emily Forrester, those moments are now overshadowed by a diagnosis they describe as “every parent’s worst nightmare.”

Their two-year-old daughter, Leni, has been diagnosed with Sanfilippo Syndrome Type B, a rare genetic condition often referred to as childhood dementia. The disorder, formally known as Mucopolysaccharidosis type III, gradually robs children of their physical and cognitive abilities.

In an interview with ITV News, Leni’s parents spoke about the devastating reality of the condition, which has no approved cure or widely available treatment.

“All your dreams for your child's future are taken away,” her mother, Emily, said. “To be told that she has this condition, and there is no treatment and no cure and no support… it’s completely earth-shattering.”

What Is Childhood Dementia?

Sanfilippo Syndrome is a neurodegenerative disorder caused by the body’s inability to break down certain complex sugars. Over time, these substances build up in the brain, leading to progressive damage.

According to Cure Sanfilippo Foundation, symptoms usually begin appearing between the ages of one and six. Children may initially show mild developmental delays, but the disease gradually worsens, affecting speech, mobility and behaviour.

As the condition advances, many children lose the ability to talk, walk and recognise loved ones. Life expectancy is often limited to the early teenage years.

Emily explained the process in stark terms. Without treatment, she said, Leni’s body will slowly be overwhelmed by “toxic waste,” causing irreversible damage.

The Urgency of Early Treatment

For families like the Forresters, time is not just precious, it is critical.

“Early treatment is key for these children,” Emily said. “If she has to wait six months, that could mean she can no longer talk. If she waits 12 months, that could mean she loses the ability to walk.”

Although experimental therapies, including gene-based approaches, are being developed, access remains a major hurdle. Some clinical trials are expected to take place in the United States later this year, but Leni is not currently eligible.

Her parents are now campaigning for UK patients to be included in these trials, arguing that promising science already exists but remains out of reach for many families.

A Family's Fight For Hope

In response to the diagnosis, the Forresters have launched a fundraiser to support Leni’s care and potential treatment options. They have also pledged to donate part of the funds to Great Ormond Street Hospital, where Leni is receiving care, and to the Cure Sanfilippo Foundation, which supports affected families.

So far, donations have crossed $250,000, reflecting the growing awareness and concern around rare childhood conditions.

Leni’s father, Gus, said the emotional toll of the diagnosis is hard to put into words. “As parents, your role is to protect your children and provide every opportunity you can. Without any treatment, her future and her reality is very, very dark.”

Beyond fundraising, the couple is also raising awareness about childhood dementia and advocating for newborn screening programmes that could help detect such conditions earlier.

Experts working on experimental therapies say greater government investment is urgently needed. Without it, many children may never benefit from treatments that could slow or alter the course of the disease.

For now, Leni remains a cheerful two-year-old, full of life and affection. But for her parents, every passing day is a reminder of how quickly that could change, and how urgently answers are needed.

Every year, March 24 is observed as World Tuberculosis Day to spread awareness about the infectious disease. In India, it remains one of the most pressing infectious diseases. Dr Arup Halder, Consultant Pomologist at CK Birla Hospitals, CMRI says that India still accounts for roughly a quarter to over a quarter of world's tuberculosis or TB cases. "In 2023–2024, India reported around 25–26 lakh TB patients out of an estimated 27 lakh cases, reflecting improved detection but also highlighting a persistently high burden," he points out.

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While TB incidence has fallen by about 20 per cent since 2015 and mortality has also declined to roughly 21 deaths per lakh population, it still remains well above national elimination targets for 2025.

TB Could Happen Even Without A Persistent Cough

What makes TB so difficult to eliminate? While many associate TB with persistent coughing, studies show that 80 per cent of patients do not show the symptoms of cough that is "presumed" to be a common symptom. This is why, TB could go ignored until it is too late.

A research led by Amsterdam UMC and the Amsterdam Institute for Global Health and Development analyzed data on more than 600,000 individuals in Africa and Asia and found that around 82.8 per cent of those with TB had no persistent cough. The study also found that 62.5 per cent had no cough at all. The findings were published in the Lancet Infectious Diseases.

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The study in fact noted that this could be the "probable reason why, despite huge efforts to diagnose and treat the disease, the tb burden across Africa and Asia is hardly declining". Frank Cobelens, Professor of Global Health at Amsterdam UMC and Senior Fellow at the AIGHD says, "A persistent cough is often the entry point for a diagnosis, but if 80 per cent of those with TB do not have one, then it means that a diagnosis will happen later, possibly after the infection has already been transmitted to many others, or not at all."

Another 2019 study published in Elsevier notes: "Coughing does not appear to be a necessary prerequisite for TB transmission." The study further mentions, "Frequency of cough is associated with infectivity but this does not imply mechanistic causality for TB transmission."

Does It Mean Coughing Is Harmless?

The simple answer to this is: No. Coughing does not mean harmless, especially when it is a persistent one. The study only shows that TB does not always mean persistent coughing, however, if one experiences this symptom, they should always get a test done and should not ignore the symptoms.

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies working with colleagues from UT Southwestern Medical Center note that TB coughing could cause pain. This is one of the way one can distinguish the symptoms. The findings published in journal Cell notes that before this study, "no one had even shown that TB produces an irritant that acts directly on the sensory innervation of the lungs".

Corresponding author Dr Michael Shiloh, associate professor of internal medicine and microbiology at UT Southwestern said, "People with active tuberculosis can cough for months and spread disease even when they are receiving appropriate treatment."

Read: World Tuberculosis Day 2026: Theme, Origin, And Significance

What Is India Doing To Control TB Cases?

On World TB Day, President Droupadi Murmu stressed that TB continues to pose a significant public health challenge and has affected millions of lives across the world. She urged all stakeholders to work together with collective resolve to end TB once for all.

To act on it, Union Health Minister Jagat Prakash Nadda will launch a series of initiatives, including 'TB Mukt Bharat Abhiyaan - 100 Days Campaign', the TB Mukt Bharat App, and the TB Mukt Urban Ward Initiative. These measures are designed to strengthen the case detection, improve treatment adherence, and enhance last-mile delivery of TB services, especially in high-burden areas. The initiatives have also been aligned with the objectives of the National Tuberculosis Elimination Programme.