Cold sores are a common and often frustrating skin issue. While they may look like harmless blisters, cold sores are actually caused by the herpes simplex virus (HSV).

What Causes Cold Sores?

Cold sores are caused by the herpes simplex virus (HSV), which comes in two types: HSV-1 and HSV-2.

HSV-1 is the primary cause of cold sores, usually appearing around the mouth.

HSV-2 generally causes genital herpes but can also lead to cold sores.

While the appearance of cold sores caused by both HSV-1 and HSV-2 can look similar, their locations tend to differ. However, it is possible for HSV-1 to cause sores on the genitals and for HSV-2 to appear on the mouth.

How Do Cold Sores Spread?

Cold sores are highly contagious and can spread easily. The virus can be passed on through:

• Kissing or skin contact
• Sharing food, drinks, or cosmetics (such as lip balm)
• Oral sex, which can spread both cold sores and genital herpes

Even when a cold sore isn’t visible, the virus can still be spread through close contact. This makes prevention and management key to reducing outbreaks and the risk of infecting others.

Once someone contracts HSV, it stays in the body for life. While the virus remains dormant most of the time, it can reactivate and cause new sores, especially during periods of:

• Stress
• Illness
• A weakened immune system

Unfortunately, there’s no cure for the herpes virus, but the symptoms can be managed.

Symptoms of Cold Sores

Cold sores don’t just appear out of nowhere. Before the sore is visible, you may notice a tingling or burning sensation around the lips or face, which can occur several days before the sore forms. This is the best time to begin treatment to shorten the outbreak.

When a cold sore does appear, it often looks like a red, raised blister filled with fluid. The blister can be painful to touch, and there may be more than one. Cold sores usually last around two weeks and are contagious until they crust over and heal.

The Five Stages of a Cold Sore

Cold sores go through distinct stages as they develop and heal:

• Tingling and itching: You may feel these symptoms about 24 hours before the blister appears.
• Blisters: Small, fluid-filled blisters form, typically around the mouth.
• Bursting: The blisters burst and form painful sores.
• Scabbing: The sores dry out, scab over, and may itch or crack.
• Healing: The scab falls off, and the cold sore heals.

Risk Factors for Cold Sores

Certain factors can trigger the reactivation of HSV, leading to cold sores. These include:

• Infection, fever, or cold
• Sun exposure
• Stress
• Menstruation
• Dental work or injury
• Weakened immune system due to conditions like HIV/AIDS, eczema, or chemotherapy

Managing and Treating Cold Sores

There’s no cure for cold sores, but several treatments can ease the symptoms and help manage outbreaks.

Topical Ointments and Creams

Over-the-counter antiviral creams like docosanol (Abreva) or prescription ointments like penciclovir (Denavir) can help reduce the duration of an outbreak, especially if applied at the first sign of a cold sore.

Oral Medications

Prescription antiviral medications like acyclovir, valacyclovir, and famciclovir can also help, particularly for people who have frequent or severe outbreaks. Your doctor may recommend taking these medications regularly to prevent future outbreaks.

Home Remedies

There are also some home remedies that may provide relief, such as:

• Applying ice or a cold washcloth to the sore
• Using aloe vera gel or lemon balm lip balms
• Applying petroleum jelly to ease discomfort

Canker Sores vs. Cold Sores: What's the Difference?

While cold sores and canker sores may seem similar, they are quite different:

Cold sores are caused by the herpes virus, appear around the mouth, and are contagious.

Canker sores are not contagious and appear as ulcers inside the mouth or throat.

Preventing the Spread of Cold Sores

To avoid spreading cold sores:

• Wash your hands frequently
• Avoid close contact with others during an outbreak
• Don’t share food, drinks, or personal items like lip balm

Cold sores can be a persistent issue, but with proper care and management, you can reduce the frequency of outbreaks and prevent spreading the virus to others.

Vaccines are like insurance; they’re important for health as well as safe to take, said Dr NK Arora, the former Chairperson and currently a member of the National Technical Advisory Group on Immunization, NTAGI.

NTAGI is the highest advisory body on immunization in the country, which consists of independent experts who provide recommendations on vaccines after reviewing data on disease burden, efficacy, and cost-effectiveness of vaccines.

As part of the ongoing World Immunization Week, Dr. Arora, the Executive Director of The INCLEN Trust International, spoke in an exclusive interview with HealthandMe on the importance of vaccines.

Comparing vaccines to insurance, Dr Arora highlighted the importance of immunization for both the young and the elderly. He emphasized that vaccines provide preventive protection against serious diseases, much like insurance offers financial security before a crisis occurs. He also underlined that timely immunization across all age groups is essential to reduce disease burden, prevent outbreaks, and ensure long-term public health safety.

“What I will say is that vaccination is like insurance. This is insurance for our health. And so it ensures the health of our children, ensures the health of our women, and pregnant women. It will ensure the health of our adolescents where the vaccination is going on,” said the expert.

The expert also urged people not to waste their time with anti-vaccine rumors and noted that vaccines, approved and given in the public health system, are safe and free of cost. These are initiated only after rigorous trials.

“Please do not hesitate to take the vaccine,” he said, adding that “vaccines are developed after extensive studies, both before it is first used in human beings and then again in human beings. And safety is something of paramount importance”.

He said people must get a vaccine, not when sick, but when we are in good health, and importantly urged the need to dispel myths around vaccines.

“I would like to assure all my readers that all the vaccines which are approved and given in the public health system are safe. Occasionally, you will hear some misinformation, some rumor, and this needs to be dispelled. If you are not very sure, please contact your physician, the nearest physician who looks after you and your family, and get clarifications from them. Rather than putting your weight on social media news and hearsay from neighbors and others, please get it. But I again assure you that all the vaccines available in India today are very safe”.

World Immunization Week

World Immunization Week is observed every year from April 24 to 30. The theme for 2026 is ‘For Every Generation, Vaccines Work.’

According to the WHO, vaccines have saved more than 150 million lives over the past 50 years.

"That’s 6 lives every minute, every day, for more than 5 decades," the WHO said.

Currently, more than 30 life-threatening diseases and infections are prevented by vaccines.

However, 20 million children missed at least one vaccine dose in 2024, leaving far too many at risk of preventable disease.

Vaccination in India: Progress with Gaps

In India, vaccines have played a significant role in improving public health. The country's immunization campaigns have been key to eradicating polio and smallpox. It has also eliminated yaws and maternal and neonatal tetanus in India. In addition, child mortality rates, measles-rubella, and tuberculosis have also been considerably reduced.

As per an official government statement, full immunization coverage has risen from 62 per cent in 2015 to 98.4 per cent in January 2026.

The percentage of zero-dose children to the total population has declined from 0.11 per cent in 2023 to 0.06 per cent in 2024.

However, gaps remain in child vaccination. These include:

Only 76.4 per cent of children (12–23 months) are fully vaccinated (NFHS-5)

India accounts for 6.4 per cent of global zero-dose children and 49.2 per cent in South Asia.

In 2024, 909,000 children remained unvaccinated, while 454,000 were partially vaccinated.

In a shocking case highlighting delayed diagnosis, a UK-based man visited doctors 24 times in a year for persistent back and leg pain but was repeatedly dismissed. He died just 12 days after being diagnosed with cancer.

The symptoms of 61-year-old Nigel began with lower back and leg pain. As the cancer spread across his body, he suffered from indigestion and severe weight loss. His doctors ignored his symptoms and could not even pinpoint the exact cancer till his death.

It was only a week after his death that the doctors were able to find that Nigel had pancreatic cancer — a type of cancer that often goes undiagnosed due to a lack of early detection tests, said his wife, Liv Williams, writing in an essay for Metro.co.uk.

“Nigel saw a healthcare professional 24 times, and even then, we didn't know it was pancreatic cancer. If something like the breath test had been available, maybe Nigel could have had treatment to give him more time with us,” Liv explained.

Also read: Former US Senator Ben Sasse Opens Up About Battle With Terminal Stage 4 Pancreatic Cancer

Nigel, a father of three, began experiencing lower back and leg pain in early 2023. Liv said that his primary care doctor referred him to a physiotherapist, but the wait took months and his condition worsened. He also developed serious indigestion.

“From March to June, Nigel sought medical advice, and each time he was sent away, either empty-handed or with medication for pain or indigestion,” she said.

Thinking the pain must be related to a spinal issue, the family paid out-of-pocket for an MRI. The lumbar spine MRI scan revealed nothing.

"But what is it then?, we asked in frustration numerous times; always to be told it would get better on its own," Liv wrote in the essay.

By July, Nigel could not stand the pain, and Liv was forced to take him to the Emergency Room (ER).

“His painful leg was getting thinner and thinner, like it was wasting away, and the pain was unbearable,” she said. Nigel lost significant weight, struggled to eat, relied on crutches, and could not sleep due to constant pain.

“Just before Christmas, I demanded a blood test from his GP – but three weeks later, a few days before the scheduled tests, Nigel couldn't urinate, which left him in agony,” she added. A visit to the ER was unfruitful as they had to rush back due to his pain.

The next time they visited the hospital, Nigel "screamed with pain", and seeing this, "a nurse promptly set him up on a bed with an IV".

The next day, the doctors informed Liv that Nigel had cancer. But as it had metastasized so much that his doctors could not pinpoint the exact cancer.

In just 12 days on February 9, 2024, Nigel died surrounded by his family.

Also read: Benjamin Netanyahu Undergoes Treatment For Early-stage Prostate Cancer: Symptoms You Should Not Ignore

What Is Pancreatic Cancer? Know The Warning Signs

Pancreatic cancer has long been one of the toughest challenges in oncology. With a five-year survival rate hovering around 13 percent and recurrence rates approaching 80 percent after treatment, the odds have historically been stacked against patients.

The prevention and early detection remain vital.

Experts warn that pancreatic cancer often masquerades as common ailments, delaying diagnosis. Here are some early symptoms that should never be ignored:

• Abdominal or back pain that worsens over time or eases when leaning forward.
• Unexplained weight loss without changes in diet or exercise.
• Jaundice, including yellowing of the eyes and skin, sometimes with intense itching.
• Changes to urine or stool, such as dark urine or pale, greasy stools.
• New-onset diabetes without obvious risk factors.
• Persistent fatigue unrelated to poor sleep or lifestyle

Kidneys are extraordinary organs that perform critical tasks on a continual basis, e.g., filtering out waste, keeping electrolytes balanced, controlling blood pressure, and providing metabolic stability.

However, many people don’t pay enough attention to keeping their kidneys healthy until they discover that substantial damage has already happened.

Some of the most prevalent and underestimated threats to kidney functioning include uncontrolled blood pressure, chronic anxiety, and unhealthy living.

The Effect Of Hypertension On Kidney Function

Hypertension (high blood pressure) is considered one of the most prevalent causes of CKD (chronic kidney disease) worldwide.

The kidneys need the support of a complicated design of tiny blood vessels to carry out their task of removing waste from the bloodstream. An ongoing and increased blood pressure level will slowly harm these small blood vessels by reducing their ability to function normally. As time passes, this injury will result in scar formation of the kidney tissue, causing a continual decline in the kidney’s ability to filter.

Hypertension is known as a silent killer because it frequently has no symptoms for many years. By the time someone experiences symptoms of high blood pressure, their kidneys may have already been damaged for a considerable period.

Chronic stress is often overlooked as an indirect cause of kidney damage. When we are under chronic stress, our sympathetic nervous system is activated, and the amount of stress hormones (cortisol and adrenaline) in our bodies increases.

These physiological changes lead to prolonged increases in blood pressure and blood glucose; both of these risk factors are bad for our kidneys. Chronic stress may cause people to engage in unhealthy coping strategies like poor diet, smoking, consuming alcohol, or not being physically active, which also increases their risk of kidney damage.

Our long-term kidney function is largely determined by lifestyle choices, including our dietary habits. Diets high in sodium, processed foods, and unhealthy fats increase the probability that you will develop hypertension, metabolic disorders, or some combination of both of these, which puts even more strain on your kidneys.

The sedentary lifestyle associated with obesity, insulin resistance, and cardiovascular disease are all significant contributors to chronic kidney disease. Dehydration, taking large amounts of over-the-counter medications (especially NSAIDs), and using tobacco products are all additional risk factors for progressive loss of kidney function.

Preventative Interventions For Kidney Health

Many of these risk factors can be addressed through prevention.

Regular monitoring of blood pressure, using mindfulness and other methods to manage stress levels, and maintaining a healthy diet full of fruits, vegetables, and whole grains will all help to reduce the strain on your kidneys.

Regular health screenings for people who have some of the above-mentioned risk factors (e.g., diabetes, high blood pressure, etc.) will give people an opportunity to identify problems early, giving them time to adjust their lifestyle or possibly seek some other type of treatment (e.g., taking medication).

The Importance of Early Awareness and Intervention

Gaining and maintaining awareness of what contributes to the health of the kidneys can help protect the kidneys.

Gaining awareness of and taking action against hidden risks, such as high blood pressure or chronic stress, and making positive changes to your lifestyle will help maintain kidney function and minimize the likelihood of developing long-term complications in the future.

Early intervention is the most effective method for protecting the health of your kidneys.