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Cold sores are a common and often frustrating skin issue. While they may look like harmless blisters, cold sores are actually caused by the herpes simplex virus (HSV).
Cold sores are caused by the herpes simplex virus (HSV), which comes in two types: HSV-1 and HSV-2.
HSV-1 is the primary cause of cold sores, usually appearing around the mouth.
HSV-2 generally causes genital herpes but can also lead to cold sores.
While the appearance of cold sores caused by both HSV-1 and HSV-2 can look similar, their locations tend to differ. However, it is possible for HSV-1 to cause sores on the genitals and for HSV-2 to appear on the mouth.
Cold sores are highly contagious and can spread easily. The virus can be passed on through:
Even when a cold sore isn’t visible, the virus can still be spread through close contact. This makes prevention and management key to reducing outbreaks and the risk of infecting others.
Once someone contracts HSV, it stays in the body for life. While the virus remains dormant most of the time, it can reactivate and cause new sores, especially during periods of:
Unfortunately, there’s no cure for the herpes virus, but the symptoms can be managed.
Cold sores don’t just appear out of nowhere. Before the sore is visible, you may notice a tingling or burning sensation around the lips or face, which can occur several days before the sore forms. This is the best time to begin treatment to shorten the outbreak.
When a cold sore does appear, it often looks like a red, raised blister filled with fluid. The blister can be painful to touch, and there may be more than one. Cold sores usually last around two weeks and are contagious until they crust over and heal.
Cold sores go through distinct stages as they develop and heal:
Certain factors can trigger the reactivation of HSV, leading to cold sores. These include:
There’s no cure for cold sores, but several treatments can ease the symptoms and help manage outbreaks.
Over-the-counter antiviral creams like docosanol (Abreva) or prescription ointments like penciclovir (Denavir) can help reduce the duration of an outbreak, especially if applied at the first sign of a cold sore.
Prescription antiviral medications like acyclovir, valacyclovir, and famciclovir can also help, particularly for people who have frequent or severe outbreaks. Your doctor may recommend taking these medications regularly to prevent future outbreaks.
There are also some home remedies that may provide relief, such as:
While cold sores and canker sores may seem similar, they are quite different:
Cold sores are caused by the herpes virus, appear around the mouth, and are contagious.
Canker sores are not contagious and appear as ulcers inside the mouth or throat.
To avoid spreading cold sores:
Cold sores can be a persistent issue, but with proper care and management, you can reduce the frequency of outbreaks and prevent spreading the virus to others.
A majority of women may experience infections during the crucial phase of pregnancy. Some infections during pregnancy may also not show clear symptoms. However, timely awareness and prevention can protect both the mother and the baby.
Pregnancy is a special and sensitive phase in a woman’s life. While most women focus on nutrition and regular check-ups, infections during pregnancy can often be neglected.
Some infections may cause only mild symptoms in the mother but can seriously affect the unborn baby if not detected early. Hence, regular screening, good hygiene, and timely medical care are crucial to prevent most pregnancy-related infections and ensure a safe and healthy pregnancy.
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A severe influenza A virus, commonly known as seasonal flu, may not only leave you coughing and feeling feverish, but also silently damage your heart, increasing the risk of heart attacks, according to a study.
A team of researchers from the Icahn School of Medicine at Mount Sinai, New York, US, unraveled that the influenza A virus directly damages the heart by hijacking immune cells. This leads to long-lasting cardiac dysfunction even after the lung infection is cleared.
The study, published in February 2026 in the journal Immunity, focused on an immune cell, known as pro-dendritic cell 3.
The researchers revealed that the pro-dendritic cell 3 acts as the ‘Trojan horse’ of the immune system during flu infection and carries the virus to the heart from the lungs.
Once in the heart, it produces large amounts of type 1 interferon and triggers the death of cardiomyocytes, impairing cardiac output.
Importantly, the findings showed that an annual flu vaccine can prevent damage to the heart.
“We have known for years that the frequency of heart attacks increases during flu season, yet outside of clinical intuition, scant evidence exists of the underlying mechanisms of that phenomenon,” said senior author Filip Swirski, Director of the Cardiovascular Research Institute at the Icahn.
“These findings offer great promise for the development of new therapies, which are desperately needed since there are currently no viable clinical options to prevent cardiac damage,” Swirski added.
The team studied autopsies of 35 hospitalized patients who died of influenza. Of these, more than 85 percent had at least one significant cardiovascular comorbidity, such as hypertension. A majority of them also had multiple comorbidities, including atherosclerosis and cardiac fibrosis, underscoring cardiovascular disease as a major driver of influenza mortality.
The study also provided evidence that a cutting-edge modified mRNA treatment that dampens an interferon signaling pathway in the heart can significantly mitigate cardiac damage following viral infection while preserving the protective antiviral response of the immune system.
“The hopeful news for patients is that by injecting a novel mod-RNA therapeutic that modulates the IFN-1 signaling pathway, we reduced levels of cardiac damage, as evidenced by lower troponin, and improved cardiac function, as measured by higher left ventricular ejection fraction,” explained Jeffrey Downey, a member of Dr. Swirski’s laboratory who served as lead author.
Global statistics show that influenza A viruses cause an estimated 1 billion infections each year. This ranges from seasonal flu outbreaks locally to pandemics globally.
While most infections are mild and self-resolving, in some cases, they can become severe or even fatal. When the virus travels to the heart, it triggers the death of cardiomyocytes -- specialized muscle cells that are responsible for the rhythmic contraction and relaxation of the heart.
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Ramzan, the holiest month in Islam, marked by dawn-to-dusk fasting, poses health risks for people with diabetes. Health experts urge patients to consult their doctors before observing the fast.
Ramzan is a period of intense spiritual reflection, self-discipline, and devotion for Muslims worldwide. During the month-long fasting period, the believers refrain from eating and even drinking (including water), from dawn to sunset.
The faithful eat a modest meal (sehri) before the first light of dawn to provide energy for the day. The fast is broken at sunset, traditionally starting with dates and water, followed by a larger meal (iftar).
According to health experts, for individuals whose diabetes is well controlled, fasting may be possible with proper adjustments.
"Diabetes requires regular monitoring, balanced meals, and timely medication. When eating patterns change during Ramzan, blood glucose levels can fluctuate. That is why I strongly recommend consulting your doctor before you plan to fast,” Dr. Saptarshi Bhattacharya, Senior Consultant, Endocrinology, Indraprastha Apollo Hospitals, told HealthandMe.
The expert advised people not to skip sehri, and to include complex carbohydrates such as whole grains, along with protein like eggs, dal, or curd, and plenty of fluids to help maintain stable glucose levels throughout the day.
At iftar, avoid overeating. Start with light, balanced food and limit fried items, sweets, and sugary drinks, as these can cause a sudden spike in blood glucose, Dr. Bhattacharya said.
Type 2 Diabetes patients with good glycemic control, lifestyle management, or stable oral medications can fast safely.
However, those on multiple insulin doses, with complications, or with poor control are considered moderate to high risk, Dr. Kartik Thakkar, Consultant Medicine, Ruby Hall Clinic, told HealthandMe.
The health expert also noted that most Type 1 diabetes patients are considered high risk, especially those with brittle diabetes, frequent hypoglycemia (low blood sugar), or a history of diabetic ketoacidosis (DKA). Many are medically advised not to fast, particularly if glucose control is unstable.
Children and adolescents with type 1 diabetes are considered high risk and are usually advised against fasting due to the unpredictable nature of insulin requirements.
Dr. Thakkar said that such individuals fall into the very high-risk category and are medically exempt from fasting.
The expert also suggested clinical tests to determine whether a diabetic patient is fit to fast. These include:
A diabetic patient must break the fast if:
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