The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

Diwali is traditionally associated with celebrations, family gatherings, illuminated homes and the sound of festivities. However, for women who are pregnant, the festive season can bring an additional health concern that often goes unnoticed: deteriorating air quality. The combination of firecracker emissions, vehicular pollution, construction dust and seasonal changes can significantly increase the concentration of pollutants in the air, making it particularly important for expectant mothers to be mindful of their surroundings.

Pregnancy is a period of considerable physiological and developmental change. A woman's respiratory and cardiovascular systems undergo adaptations to support the growing baby, and exposure to pollutants such as fine particulate matter (PM2.5) can add to the body's environmental burden. These particles are small enough to penetrate deep into the lungs and trigger inflammatory responses. Research has associated maternal exposure to air pollution with adverse pregnancy outcomes, including preterm birth, low birth weight and babies being small for their gestational age.

However, this does not mean pregnant women need to withdraw completely from festive celebrations. The objective should be to make informed choices, reduce unnecessary exposure and understand how precautions can be adapted at different stages of pregnancy.

First Trimester: Prioritising Early Development and Reducing Exposure

The first trimester, particularly the initial 12 weeks, is a critical period of embryonic development, when major organs and body systems begin forming. During this stage, expectant mothers may also experience nausea, fatigue, dizziness and increased sensitivity to certain environmental triggers.

Exposure to firecracker smoke and heavily polluted environments should be minimised. Although an isolated exposure does not automatically indicate harm to the pregnancy, repeated or prolonged exposure to poor air quality is best avoided.

Women in their first trimester should consider the following precautions:

- Avoid standing near areas where firecrackers are being burst or smoke is accumulating. Even brief festive activities can result in unnecessary exposure when pollution levels are high.

- Check the local Air Quality Index (AQI) before stepping outdoors. Reschedule non-essential outdoor activities when air quality deteriorates.

- Avoid participating in activities involving firecracker lighting, including sparklers and other fireworks.

- Keep indoor environments as clean as possible by avoiding excessive incense, dhoop and other smoke-producing substances.

- Maintain adequate hydration, eat balanced meals and prioritise rest, particularly if experiencing pregnancy-related fatigue or nausea.

The first trimester is also when women should be particularly mindful of their overall health rather than attempting to maintain their usual festive routines at the cost of adequate rest.

Also read: Delhi Becomes World's Most Polluted City Ahead Of Diwali, Says Swiss Agency: Experts Recommend Precautions

Second Trimester: Balancing Mobility, Physical Activity and Environmental Safety

The second trimester is often considered a relatively comfortable phase of pregnancy. Many women experience a reduction in early pregnancy symptoms and may feel more energetic, making social gatherings and festive activities easier to manage.

However, feeling physically better should not translate into overlooking environmental risks. Continued exposure to fine particulate matter and other pollutants can affect maternal respiratory health and has been associated with adverse fetal growth outcomes.

A few practical adjustments can help women enjoy the festivities without unnecessary exposure.

- Choose indoor celebrations or smaller family gatherings instead of crowded outdoor events, especially in areas with visible smoke.

- Avoid evening walks or outdoor exercise when AQI levels are poor. Physical exertion can increase the volume of air inhaled, potentially increasing pollutant exposure.

- If outdoor movement is unavoidable, a properly fitted N95 mask may help reduce exposure to particulate matter. However, it does not eliminate all pollutants or replace the need to avoid heavily polluted environments.

- Keep windows closed during periods when outdoor pollution is particularly high. Ventilate the house when outdoor air quality improves.

- Continue pregnancy-appropriate physical activity as advised by the treating obstetrician, adapting the routine according to local air quality conditions.

Women should also avoid prolonged standing, excessive physical exertion and crowded spaces where access to clean air may be limited.

Also read: Can Prolonged Exposure To PM2.5 Increase The Risk Of Blood Clots And Stroke?

Third Trimester: Protecting Maternal Respiratory Health and Avoiding Physical Strain

During the third trimester, the growing uterus places additional pressure on the diaphragm, and many women experience breathlessness, fatigue, disturbed sleep and reduced physical mobility.

When these changes coincide with poor air quality, the importance of limiting exposure becomes even more relevant. Maternal exposure to air pollution has been associated with an increased likelihood of preterm birth and low birth weight, although these outcomes are influenced by several factors and cannot be attributed to a single exposure.

At this stage, the focus should be on maintaining comfort, avoiding unnecessary physical strain and ensuring timely medical attention when required.

Expectant mothers in their third trimester should:

- Avoid crowded firecracker celebrations, open-air events and prolonged exposure to smoke.

- Prefer celebrations at home or in well-ventilated indoor environments with cleaner air.

- Avoid lifting heavy decorations, climbing ladders or undertaking physically demanding festive preparations.

- Keep antenatal appointments on schedule and discuss any respiratory discomfort or concerns about pollution exposure with their obstetrician.

- Avoid unnecessary late-night outings, particularly when pollution levels tend to remain elevated.

Women experiencing persistent breathlessness, chest discomfort, wheezing or unusual fatigue should not dismiss these symptoms as routine pregnancy-related discomfort.

Beyond the Trimester: Five Air-Safety Habits Every Expectant Mother Should Follow

While pregnancy progresses through different developmental stages, the need to minimise pollution exposure remains consistent throughout all three trimesters. A few simple measures can make festive celebrations safer.

1. Make AQI checks part of your daily routine

Do not rely solely on visible smoke or haze to judge air quality. Check the local AQI through official monitoring platforms such as the Central Pollution Control Board before planning outdoor activities. Pollution levels can vary considerably between neighbourhoods and throughout the day.

2. Keep indoor air cleaner

Indoor spaces are not automatically pollution-free. Smoke from incense sticks, camphor, candles and firecrackers entering through open windows can affect indoor air quality. Avoid unnecessary smoke-producing activities and consider using a properly sized HEPA air purifier, if available.

3. Choose celebrations that do not involve firecrackers

Lighting diyas, decorating the home, preparing festive meals and spending time with family are meaningful ways to celebrate without adding to firecracker-related pollution. Staying away from areas where fireworks are being burst is particularly important.

4. Do not compromise on hydration and nutrition

A balanced diet containing seasonal fruits, vegetables and adequate protein supports maternal health. Drinking sufficient water helps maintain hydration, although neither hydration nor antioxidant-rich foods can neutralise the effects of inhaled pollutants.

5. Know when to seek medical attention

Persistent coughing, wheezing, chest pain, significant breathlessness, dizziness or other unusual symptoms warrant medical evaluation. Pregnant women with asthma or existing respiratory or cardiovascular conditions should discuss an individualised pollution-safety plan with their healthcare provider.

A Healthier Diwali Begins With Informed Choices

One of the biggest misconceptions surrounding pregnancy and pollution is that precautions are necessary only when air quality becomes visibly poor. In reality, exposure to particulate matter can occur even when the air appears relatively clear. This makes awareness and preventive action important throughout the festive period.

It is equally important to remember that pregnancy does not mean putting life on hold. Women can continue to participate in meaningful traditions, enjoy family gatherings and celebrate festivals by making sensible adjustments to their environment and activities.

There is no single trimester in which exposure to air pollution can be considered completely safe, and no precaution can eliminate exposure entirely. The emphasis should be on reducing avoidable exposure, following local air-quality advisories and seeking individualised medical guidance.

Diwali should be a celebration of light, happiness and togetherness. For expectant mothers, a little extra planning can help ensure that the festivities remain centred on what matters most: their health, comfort and the well-being of their growing baby.

By Dr Sudeshna Ray, Associate Director Obstetrician, Gynaecologist, Jaslok Hospital and Research Centre, Sr Consultant in Breach Candy & HN Reliance

Breast cancer is often associated with a distinct lump, but not all breast cancers grow in the same way. Invasive lobular carcinoma (ILC), a type of breast cancer that begins in the milk-producing lobules, can be particularly challenging to detect because it may not form a clearly defined lump. Its subtle presentation can make early detection difficult, even when a woman undergoes routine breast imaging.

ILC accounts for approximately 10–15% of invasive breast cancers. Unlike invasive ductal carcinoma, which often forms a more defined mass, lobular cancer cells tend to spread through breast tissue in thin, single-file patterns. They may infiltrate the surrounding tissue without significantly altering its overall structure. As a result, the cancer can blend with normal breast tissue and may not appear as an obvious abnormality on a mammogram.

Why mammograms may miss lobular breast cancer?

Mammography uses X-rays to identify suspicious changes in breast tissue. However, invasive lobular carcinoma may appear as a subtle area of density, tissue distortion or thickening rather than a distinct mass. These changes can be difficult to distinguish from normal breast tissue, particularly in women with dense breasts, where overlapping tissue can obscure abnormalities.

Another challenge is that lobular cancer may involve a relatively extensive area of the breast without producing a clear boundary. Consequently, imaging may underestimate the actual size or extent of the disease. This does not mean mammography is ineffective; rather, it highlights the limitations of any single screening test.

What symptoms should women watch for?

Women should not rely solely on the presence of a lump to identify a possible breast problem. Invasive lobular carcinoma may present as a feeling of fullness, thickening or firmness in one area of the breast. Other possible changes include skin dimpling, a change in breast shape or size, or a newly inverted nipple.

These symptoms do not necessarily indicate cancer, but persistent or unexplained changes warrant medical assessment. A normal mammogram should not automatically end the investigation if a breast surgeon remains concerned following a clinical examination.

Also read: Unspoken Side Of Breast Cancer: Experts Discuss Recurrence Risk, Emotional Toll & Societal Impact At Times Health Summit 2026

What happens when a mammogram is inconclusive?

Doctors may recommend additional investigations depending on the symptoms, examination findings and individual risk factors. Breast ultrasound can help assess a suspicious area, while magnetic resonance imaging (MRI) may be useful when lobular cancer is suspected or already diagnosed and its extent needs clarification.

A biopsy, in which a small tissue sample is examined under a microscope, is generally required to confirm the diagnosis. The choice of investigations should be individualised rather than based on the assumption that every woman needs additional imaging.

Why awareness and follow-up matter

Regular screening remains important, even when a woman has no symptoms. However, screening recommendations vary according to age, personal risk and family history. Breast self-awareness also plays a role in helping women recognise changes that are unusual for them.

The key message is that a normal mammogram is reassuring, but it is not an absolute guarantee that breast cancer is absent. Persistent breast changes deserve timely evaluation, and further assessment may be necessary when symptoms and imaging findings do not agree.

Early diagnosis depends on appropriate screening, awareness of symptoms and prompt follow-up when something does not appear right.

As an orthopaedic surgeon, one question I increasingly hear from patients in their 30s and 40s is, “Doctor, am I too young to have knee problems?”

The answer is that while significant arthritis is less common at this age, knee pain certainly isn’t. And more often than not, our everyday habits can play a role.

We spend hours sitting at our desks, take the elevator instead of the stairs, gain a few kilograms over the years, and then expect our knees to perform perfectly during an occasional game of badminton or a weekend trek. Unfortunately, our joints don’t quite work that way.

Why Regular Physical Activity Is Important For Knee Health

The first thing I tell my patients is that knees are meant to be used, not preserved in a showcase. Avoiding physical activity out of fear of wear and tear can do more harm than good. Walking, cycling, swimming and regular exercise help maintain joint function. Just as importantly, strong thigh and hip muscles provide the support and stability our knees need.

The second point is weight. We often underestimate how much our knees have to carry. During everyday activities, the forces passing through the knee can be several times our body weight. Losing even a few kilograms can make a meaningful difference, particularly for people who are overweight.

Also read: In-Toeing In Children: When It Needs Assessment

The Weekend Warrior Syndrome: Why Inactivity Can Hurt Your Knees

Then there is what I call the weekend warrior syndrome. Five days of inactivity followed by two hours of intense sport is hardly a recipe for healthy joints. Our muscles and tendons need regular conditioning to handle physical demands. Consistency, rather than occasional bursts of enthusiasm, is what builds resilience.

Another misconception I frequently encounter is that squatting, sitting cross-legged or climbing stairs will inevitably damage the knees. These are natural movements, not problems in themselves. For most people with healthy knees, they are perfectly acceptable when performed comfortably and with adequate strength. However, pain should never be ignored or repeatedly pushed through.

When Should You See An Orthopaedic Specialist?

Finally, not every click or crack is a sign of arthritis. However, persistent pain, swelling, locking or instability deserves medical attention. Early diagnosis can often help address problems before they become more troublesome.

My message is simple: don’t wait for your knees to hurt before you start looking after them.

You don’t need expensive supplements, fancy equipment or complicated routines. Move a little more, sit a little less, strengthen your muscles and keep your weight in check.

After all, the goal isn’t just to have pain-free knees today, but to keep them healthy enough to help you live independently, actively and confidently for decades to come.

Invest in your knees at 30, so they can continue supporting you at 70.

By Dr. Vaibhav Bagariaia, Dr. Vaibhav Bagaria, Director, Orthopaedics, Sir HN Reliance Foundation Hospital