The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

Josie Gibson, English TV personality, opened up about her secret health disorder and that she is turning to a "last resort" surgery for the same. She revealed that this health challenge has left her with extreme pain. This Morning presenter, 40, appeared on the show and spoke to Cat Deeley and Ben Shephard about being diagnosed and having a "lipodema" body. She said, "A couple of years ago somebody actually said on Instagram, 'you have got a typical lipodema body'. I thought, 'what's lipedema?'"

She said she did not even have a clue, but she knew something was not right. But she did not know what lipedema was. She got diagnosed about a year ago and had a surgery. She told her fans that she has been "constantly fighting" her genetics.

What Did Josie Gibson Reveal About The Surgery?

Speaking on ITV’s This Morning, Gibson said surgery was a “last resort” but described herself as happy with the results after spending around £7,000 on liposuction to treat her calves. She explained that the procedure, which combines liposuction with a technique that tightens the skin, had to be carried out in stages.

“The last thing I want to do is put myself through surgery, but it was my last resort,” she said, adding that she had only treated her calves so far. Gibson said the change in her appearance had been significant, telling viewers: “All my life I have wanted to have ankles. I’ve finally got them.”

What Is Lipedema?

Lipoedema is a condition that mainly affects women and causes an abnormal build-up of fat, most commonly in the legs and sometimes the arms. It can make the lower body appear out of proportion and is often associated with pain, tenderness and a feeling of heaviness.

Gibson said she had always felt something “wasn’t right” with her body but was only diagnosed with lipoedema last September. She said specialists told her that diet and exercise would not remove the affected fat. “They said I could train seven days a week and I wouldn’t get rid of lipoedema fat like that,” she said.

Describing the impact of the condition, Gibson said her legs felt increasingly out of place compared with the rest of her body and that symptoms had worsened over time, now also affecting her arms. “I could train, train and train but really, I’m going down the surgery route now,” she added.

Lipoedema specialist Dr Dennis Wolf, who also appeared on the programme, said the condition is not currently treated on the NHS due to the lack of a formal diagnostic test and limited research. He said doctors often rely on symptoms and patient experiences to identify it and believes some people may have a genetic predisposition.

Dr Wolf explained that lipoedema fat is resistant to weight loss, meaning people can exercise and diet without seeing changes in affected areas. While surgery is the most common way to manage the condition, other treatments include compression garments to help reduce discomfort.

Gibson also shared a light-hearted moment from her surgery, admitting the anaesthetic left her flirtatious and apologetic towards her surgeons.

Fewer people are dying of heart disease, however, as per a new report from the American Heart Association (AHA), it is still the leading cause of death in the US. While the report noted a drop in rates of deaths by heart diseases for the first time in five years, the report also noted that it kills more American than any other condition. The report was published early Wednesday in the journal Circulation.

What Did The AHA Report Reveal?

The report found that annual rates of heart disease deaths have in fact decreased by 2.7% between 2022 and 2023. This means it went from 941,652 to 915, 973. However, cardiovascular diseases still killed more people in the US than cancer and accidents combined.

The report found that deaths caused by blockages in the coronary arteries, the blood vessels supplying the heart, fell by 5.9%, dropping from 371,506 to 349,470 over the same period. Coronary artery disease, a major cause of heart attacks, still claims two lives every three minutes. Other vessel-damaging chronic conditions also remain widespread.

The report found that the share of U.S. adults with high blood pressure edged up to 47.3%, while overall obesity rates dipped slightly to 50%. However, obesity is increasing among children and teenagers, rising from 25.4% to 28.1% in those aged 2 to 19.

Prevention remains the most powerful tool to reduce heart disease deaths, experts say. Because heart disease cannot be cured, waiting for symptoms often means focusing only on treatment rather than stopping the problem early. Early prevention, by contrast, has a much bigger impact on saving lives.

The report highlights four key lifestyle habits for heart health: eating a balanced diet, staying physically active, getting enough sleep and avoiding tobacco. It also stresses four important health measures: managing weight, cholesterol, blood sugar and blood pressure.

Together, these eight factors could prevent up to 40% of heart disease deaths and cut the risk of developing serious heart disease symptoms by as much as 74%. These same habits also benefit the brain, helping slow brain ageing and lower the risk of dementia, especially by keeping blood pressure under control.

Heart Health Is Also an Economic Issue

Cutting down cardiovascular disease in the U.S. would not only help people live healthier lives, it could also ease the strain on the economy, experts say. Heart disease carries a massive financial cost, with an estimated $414.7 billion spent each year on direct treatment and indirect losses between 2021 and 2022.

Even though the benefits of healthy habits are well known, getting people to prioritize heart health remains difficult. Only one in four U.S. adults meets national guidelines for both aerobic and muscle-strengthening exercise. Control of chronic conditions is also lacking, with less than half of Americans with type 2 diabetes managing their disease effectively.

Experts stress that regular physical activity, tailored to individual ability, can make a real difference. Simple, consistent movement and timely health checkups can go a long way in protecting both personal health and the wider economy.

Been noticing yellow deposits on your or your loved ones' eyelids? It may be a sign of a future heart attack, experts warn.

Xanthelasma is a harmless, yellow growth that appears on or around the corners of your eyelids next to the nose. These lesions are often painless and can vary in size, sometimes merging to form larger patches.

But while xanthelasma itself is not a disease, its development can signal elevated cholesterol levels and an increased risk of cardiovascular diseases such as coronary artery disease and atherosclerosis, which can lead to a heart attack in the future.

According to Dr Sudhir Kumar, a neurologist associated with Apollo Hospital in Hyderabad, xanthelasma patches can appear even when blood tests show normal cholesterol levels and should prompt 'a proper lipid evaluation, not just a cosmetic procedure'.

In an X post, he noted: "These yellow patches on the eyelids are NOT just cosmetic. They are called xanthelasma and they can be your skin’s clue to hidden heart risk. These are:

1. Often linked to abnormal lipids

2. Can be present even when LDL cholesterol is normal

3. Strongly associated with atherosclerosis & heart disease"

READ MORE: Heart Cells Can Regrow After A Cardiac Arrest, Scientists Say

Heart attacks occur when blood flow to the heart is severely reduced or blocked due to a buildup of plaque which is made of fat, cholesterol and other substances in the heart's arteries.

During a heart attack, a lack of blood flow causes the cells and tissue in the heart muscle to die, leading to irreversible damage that can result in serious complications like arrhythmias, heart failure, cardiogenic shock, or cardiac arrest

It is one of the leading causes of death in the country. Four Indians experience a heart attack every minute, with one in four dying of the cause. Experts have also noticed a rising trend of nearly 50 percent of heart attack patients being under the age of 40, with half of all heart attacks in Indian men occurring under 50.

Who Is At The Highest Risk For Xanthelasma?

• Being Overweight.
• A tobacco product habit.
• High cholesterol.
• Diabetes.
• High blood pressure.
• Family history of high cholesterol or xanthelasma are also at the highest risk of developing yellow plaques.

Can Xanthelasma Be A Sign Of Other Diseases?

Additionally, it can also indicate thyroid issues such as hypothyroidism. Xanthelasma and hypothyroidism are linked as both thyroid dysfunction and high cholesterol/lipid levels, often seen with hypothyroidism, can cause the eyelid plaques.

Coronary Artery Disease: The Silent Killer

Coronary artery disease (CAD) is one of the most common illnesses that can cause a heart attack in people. It develops over the years and has no clear signs and symptoms apart from a heart attack.

The illness begins due to a buildup of fats, cholesterol and other substances known as plaque in and on the artery walls.

Over time, this can cause narrowing or blockage of the coronary arteries and block the supply of oxygen-rich blood to heart which can lead to chest pain (angina), shortness of breath and ultimately, heart attacks.

Typically, those above the age of 45, having a biological family member with heart disease, lack of sleep, smoking, consuming saturated fats along with other autoimmune diseases such as lupus and rheumatoid arthritis, can increase the risk of developing CAD.

Nearly one in 10 Indian adults suffer from CAD and about two million people die from the disease annually. Apart from this, about 18 to 20 million American adults aged 20 and older are also affected about the disease.