The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

As temperatures fall, a growing number of people are seeking medical advice for sudden, painful rashes and nerve-related discomfort. Superdrug Online Doctor has reported a 50% rise in patients requesting consultations for shingles over recent weeks. Shingles develops when the chickenpox virus, which stays dormant in the body after childhood infection, becomes active again later in life.

What Is Shingles?

Shingles, also known as herpes zoster, is a viral illness that causes a painful, blistering rash, usually appearing on one side of the body. It occurs when the varicella-zoster virus, which causes chickenpox, becomes active again after lying dormant in the nerves for many years. This reactivation is more likely when the immune system is weakened.

Symptoms often begin with burning, tingling, or itching in a specific area, followed by clusters of fluid-filled blisters that eventually dry out and form scabs. Starting antiviral treatment early can help reduce the severity and length of the infection. A shingles vaccine is also available and is recommended, particularly for people over the age of 50, to lower the risk of developing shingles and to prevent complications such as long-lasting nerve pain, known as postherpetic neuralgia.

Who Is Most At Risk Of Shingles?

The condition is more likely to affect older adults and people with weakened immune systems. Dr Babak Ashrafi, Superdrug’s Online Doctor, explained that many patients are caught off guard by how quickly symptoms appear. “Shingles often begins unexpectedly,” he said. “People may wake up with a burning or tingling sensation, followed by a rash that rapidly becomes more painful. We typically see higher numbers during colder months, when immune defences are under greater pressure.”

Winter-related factors such as stress, poor sleep, and seasonal infections can all take a toll on the immune system. When immunity dips, the virus responsible for shingles has a greater chance of reactivating, increasing the likelihood of flare-ups during colder periods.

Shingles Early Warning Signs To Watch For

According to the NHS, early symptoms of shingles often include a tingling, itching, or painful sensation on one side of the body. Some people may also experience headaches or feel generally unwell before a rash appears. The rash usually develops a few days later and is most commonly seen on the chest or abdomen, although it can occur anywhere on the body.

Superdrug Online Doctor has outlined five situations where people should seek prompt medical advice rather than rely on self-care. These include cases where:

• the rash appears on or near the eye
• pain is severe or spreading
• the person has a weakened immune system
• the individual is pregnant
• symptoms are worsening quickly

Shingles Treatment

Superdrug Online Doctor provides an online assessment and photo-diagnosis service, allowing clinicians to review symptoms remotely. Where appropriate, patients can be prescribed antiviral medication without needing to wait for a GP appointment.

Dr Ashrafi stressed the importance of acting quickly, adding: “The most important advice is not to wait and see. Starting treatment early can make a significant difference to recovery and long-term outcomes.”

Doctors are reporting a change in the way the flu is presenting as a new strain spreads across the UK. Hospital admissions linked to the flu rose sharply at the beginning of the year, with an average of 2,924 people a day admitted by January 4. Four hospital trusts have declared critical incidents, citing ongoing and intense pressure on services. These include three trusts in Surrey and one in Kent.

Surrey Heartlands Trust said winter pressures had been made worse by a rise in flu and norovirus cases. NHS national medical director Professor Meghana Pandit said the situation remains difficult, with hospitals seeing another increase in patients admitted with flu and other respiratory infections last week.

She said it is still vital for people to seek medical help when needed and reminded the public that there are many chances to get vaccinated against flu. Health Secretary Wes Streeting also stressed that flu can be dangerous, especially for older adults, young children, and those with existing health problems. He urged everyone who qualifies to get their flu vaccine as soon as possible, calling it the best form of protection.

Doctors Report Unusual Symptoms As New Flu Strain Spreads Across The UK

Doctors say this latest flu strain appears to be causing different symptoms. The virus, known as subclade K, is a variant of the A H3N2 type of influenza.

Dr Mark Loafman told NBC Chicago that many patients are experiencing much higher fevers than usual. He said the fever can last five to seven days, which is longer than people typically expect and is a cause for concern.

In some cases, doctors say the fever does not respond well to common medicines such as paracetamol or ibuprofen. Lung specialist Dr Juanita Mora said this strain is linked to very high temperatures, a severe and persistent cough with heavy phlegm, vomiting, diarrhoea, and widespread joint and muscle pain.

Doctors have also noticed a rise in stomach-related symptoms, including nausea and vomiting, often referred to as gastrointestinal or GI issues. Dr Loafman said that, based on what doctors are seeing, adults infected with the subclade K strain seem to be showing more signs of GI illness than usual.

According to the NHS, flu symptoms usually appear suddenly and tend to be much more severe than those of a common cold. While most people start to recover within about a week, the illness can feel particularly harsh while it lasts.

Key Symptoms of Flu

The main symptoms usually begin abruptly and include:

• A sudden high temperature of 38C or higher
• Body aches affecting muscles and joints
• Extreme tiredness or exhaustion
• A dry cough
• A sore throat
• Headaches
• Problems sleeping
• Reduced appetite
• Nausea, vomiting, or diarrhoea, which are more common in children

How To Treat Flu at Home

Most people can deal with flu symptoms at home without needing to see a doctor. The NHS advises the following self-care measures:

• Rest and Sleep: Allow your body time and energy to fight off the infection.
• Stay Warm: Use extra layers or blankets to maintain body warmth.
• Hydration: Drink plenty of fluids to prevent dehydration. Your urine should be pale yellow or clear.
• Pain Relief: Paracetamol or ibuprofen can help reduce fever and ease aches. Avoid taking combination flu medicines alongside paracetamol tablets, as this can lead to taking too much.
• Sore Throat Relief: Gargle with salt water if you are an adult, or have hot drinks such as lemon and honey to ease discomfort.

People across the UK are being urged to follow basic safety steps as concerns grow over so-called “evolving” bacteria. A few decades ago, antibiotics were routinely prescribed for a wide range of illnesses and minor infections.

Today, many GPs are far more cautious about giving them out, largely because of the steady rise in bacteria that no longer respond to treatment. Figures from the UK Health Security Agency show that close to 400 antibiotic-resistant infections are being recorded every week in England.

What Are Antibiotic-Resistant Infections?

According to the World Health Organisation (WHO), antibiotic-resistant infections develop when bacteria change over time and stop responding to the medicines meant to kill them. As a result, infections that were once easy to treat become much harder, and in some cases impossible, to cure. This can lead to serious illness, longer hospital stays, and a higher risk of death.

While antibiotic resistance can occur naturally, the WHO warns that misuse and overuse of antibiotics in both humans and animals greatly speeds up the process. This allows resistant bacteria, often referred to as “superbugs,” to survive, multiply, and spread more easily.

Why Is Antibiotic Resistance Dangerous?

The biggest risk linked to these “superbugs” is that they are much harder to treat because standard antibiotics no longer work against them. Infections caused by resistant bacteria can lead to serious complications, including pneumonia and bloodstream infections, which can be life-threatening if not controlled quickly.

In a post shared on X, the UKHSA said: “Bacteria are evolving against antibiotics, with nearly 400 new resistant infections appearing each week in England.” NHS guidance has also warned that several bacteria have already developed resistance as a result of antibiotic overuse. These include MRSA, Clostridium difficile, and the bacteria linked to multidrug-resistant tuberculosis.

A major concern is that this growing trend could eventually lead to new strains of bacteria that cannot be treated with any existing antibiotics.

How To Reduce The Risk Of Antibiotic-Resistant Infections?

According to UKHSA advice, people can play a role in slowing the spread of resistant bacteria by following a few simple precautions in daily life. These include:

• Returning unused antibiotics to a pharmacy so they can be disposed of safely and do not contribute to resistance in the environment
• Practising safe sex, particularly to reduce the spread of infections such as gonorrhoea, which is becoming harder to treat
• Staying up to date with vaccinations, which can help prevent infections in the first place
• Talking to a healthcare professional before taking antibiotics, as they are not always necessary
• Washing hands thoroughly and staying at home when feeling unwell to avoid spreading infection