The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

The journey of a breast cancer patient does not end when their treatment comes to a conclusion. There is always a risk of recurrence, which makes regular follow-ups and adherence to treatment important.

At the Times Network India Health Summit and Awards 2026 in New Delhi, a panel formed by Dr Priya Parmar, Chief Operating Officer, Indian Cancer Society, Delhi, Dr. Jyoti Wadhwa - Principal Lead of Medical and Precision Oncology, Apollo Athena Women’s Cancer Centres, New Delhi and Apollo Hospital, Gurgaon, Dr. Meenu Walia, Chairman Medical Oncology, Max Healthcare, Dr Pankaj Goyal, Sr Consultant and Unit Head, Medical Oncology, RGCI, and Vaishali Iyer, Country Head, Communications, Patient Advocacy and CSR, Novartis in India, discussed the big picture after breast cancer treatment.

During a panel discussion titled “Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes,” experts highlighted the physical, emotional, social and financial challenges that women may continue to face after treatment among many more.

What Comes After Breast Cancer Treatment?

For many women, the period after breast cancer can involve more than medical monitoring. They may face fatigue, menopausal symptoms and changes in body image after undergoing a major physical change, while concerns about intimacy, fertility and relationships can affect emotional and mental well-being.

Dr. Priya Parmar highlighted how losing a breast or hair can affect a woman's sense of identity and femininity. Some survivors also face social stigma related to marriage and fertility, while sexual health and relationship concerns may remain difficult to discuss.

The burden can be greater for women who lack family support or have limited financial resources. These circumstances may affect not only emotional recovery but also their ability to attend follow-up appointments and continue treatment.

The financial strain can become particularly difficult if cancer returns and further investigations or treatment are required.

Dr. Meenu Walia said that treatment for advanced disease can add to the economic burden faced by patients and their families.

Also read: Vanessa Trump Recovers From 'Very Invasive' Breast Cancer, Reveals Early Sign Of The Disease

Risk Of Recurrence

The risk of breast cancer recurrence is not the same for every patient. It depends on the cancer's stage and subtype, tumour grade, lymph node involvement, response to treatment and whether treatment is timely.

Dr. Jyoti Wadhwa explained that different breast cancer subtypes can follow different recurrence patterns.

Triple-negative breast cancer tends to recur earlier, often within the first two to three years after treatment. Hormone receptor-positive, HER2-negative breast cancer, however, can return even 10 to 20 years later.

She also said that patients who achieve a pathological complete response after treatment given before surgery may have a lower risk of recurrence than those with residual disease.

However, a lower estimated risk does not mean the risk is eliminated. Continued monitoring is important even for patients who have responded well to treatment.

Also read: Beyond the Lump: Overlooked Breast Cancer Symptoms That Can Delay Diagnosis

Feeling Better Is Not A Reason To Skip Follow-Ups

One concern raised by the experts was that some patients stop taking prescribed oral hormone therapy or miss appointments after their symptoms improve.

“Your first attempt at treatment is always your best attempt,” Dr. Walia said, underlining the importance of appropriate diagnosis and treatment from the outset.

Follow-up care helps doctors monitor a patient's recovery, assess treatment-related effects and make decisions based on individual clinical circumstances. The appropriate schedule and any further treatment depend on the patient's diagnosis, risk profile and medical history.

Experts also cautioned against allowing the possibility of recurrence to dominate a survivor's life. Understanding individual risk should help patients make informed decisions, rather than leave them in constant fear that cancer will return.

Post-Treatment Care Needs More Than Medical Monitoring

The long-term effects of breast cancer also have implications beyond the individual patient. Vaishali Iyer, Country Head of Communications, Patient Advocacy and CSR at Novartis in India, highlighted an estimated 140 million productive hours lost due to breast cancer care, drawing attention to its wider economic impact.

Dr. Wadhwa emphasised the need to address treatment-related concerns, including menopausal symptoms and bone health, which may require attention even after primary cancer treatment has ended.

Dr. Pankaj Goyal, Senior Consultant and Unit Head of Medical Oncology at RGCI, stressed that doctors must build trust with patients and explain recurrence risks without causing unnecessary alarm. Discussions about care should also account for patients' personal circumstances and financial constraints.

The panel discussion, titled “Take Charge Together: Shaping a Future of Greater Breast Cancer Awareness and Better Outcomes,” took place at the Times Network India Health Summit and Awards 2026.

Padma Bhushan Dr Shiv Kumar Sarin, leading hepatologist, gastroenterologist, and medical educator who also serves as the Senior Professor, Chancellor, and Director of the Institute of Liver and Biliary Sciences (ILBS), recently spoke about the dos and don’ts to maintain a healthy liver at the Times Health Summit 2026.

Held under the theme “The Blueprint for a Future-Ready Healthcare Ecosystem – Innovation. Access. Self-Reliance,” the summit brought together healthcare professionals and industry stakeholders to discuss innovation, access to treatment and policy approaches shaping India's healthcare sector.

Should You Drink Hot Water In The Morning For Bowel Movement?

The doctor addressed the daily morning ritual of drinking hot water in the morning, which a lot of people follow to release bowels.

Dr Sarin said, “Don't use hot water or anything for that matter to make you go to the toilet because it is the connection between the brain and the bowel that is very important.

He also spoke about opting for other drinks like coconut water or lemon water with honey. He said that lemon can help improve iron absorption in your body.

He added, “As per coconut water is concerned, it has potassium which is very good for your bowel health but it should still not be an everyday thing. For nimbu and honey, you should remember that honey has fructose. So if you are consuming honey, you also need to churn that out."

Also read: Fatty Liver Disease: Scientists Identify 5 Subtypes With Different Health Risks

Ideal Time for Breakfast

Many of us do not know what is the right time for breakfast. It is especially important as eating after fasting for eight to ten hours affects your energy and metabolic health throughout the day.

Dr Sarin said, "It's after sunrise. Minimum 12 hours after the last food that you have eaten. Ussay pehle galti nahi kariyega khaanay ki. Let the stomach, and the bacteria and the intestine recover."

He also spoke about whether you should have fruits for breakfast. "Breakfast should be fruits. And, low calories fruits. Avoid carbs."

Also read: The Changing Obesity Treatment Landscape: Where Does Bariatric Surgery Fit in the Age of Weight-Loss Drugs?

How Coffee Affects The Liver

There is a lot of information as well as misinformation about coffee consumption and liver health. Dr S K Sarin spoke in its favour and said that it could prevent a lot of liver conditions.

He said, "It does many things. it clears several toxic things including fat, clears the flow of bile, good enzyme inducer, prevents fibrosis of the liver and can decrease cirrhosis and also the development of liver cancer."

He also warned ignoring healthy dietary habits and simply relying on coffee is also not ideal. He added, "Coffee is not medicine, it is something which can help you prevent and not treat."

Is Your Lunch Completely Healthy?

Dr Sarin also warned against eating more amount carbohydrates than the recommended limit. He explained how sitting next to an obese person can make you feel physically lethargic as their breath may emit endogenous alcohol.

When you eat a carbohydrate-heavy meal, your digestive system breaks down carbohydrates into sugars. Certain microorganisms in the gut, including yeasts and some bacteria, can ferment these sugars and produce small amounts of ethanol, or alcohol. This is known as endogenous alcohol production.

Dr Sarin recommends eating low-carb meals for lunch like sprouts, vegetables, yoghurt, buttermilk or low-sugar fruits.

Late-Night Eating Is A Red Flag

Dr Sarin recommends having dinner before sunset. He also said that having late-night dinners could disrupt your sleep.

He added, "Obesity during youth increases the risk of heart disease later in life. After the age of 40, eating one meal a day may have health implications. The total daily calorie intake should not exceed 300–400. Avoid eating late at night. Eating late can also affect your insulin resistance."

Yearly Screening To Keep Liver Health In Check

Dr Sarin also said that thin people can also have unhealthy fat that may cause fatty liver. He recommended yearly screens to keep liver health in check.

He said, "Even thin people can have excess body fat and low muscle mass, which may affect their health. Being thin does not necessarily mean being healthy. Maintaining good muscle mass is important."

In a significant step toward advancing xenotransplantation—the transplantation of organs or tissues from animals into humans—in India, a dedicated department has been established, with research and regulatory work underway. The country’s first animal-to-human organ transplant could follow, subject to government approval and the establishment of legal and ethical guidelines.

The initiative aims to help bridge the organ shortage in the country, Dr. Shikhar Tripathi, Director of the Department of Xenotransplantation Sciences at Sir Ganga Ram Hospital, New Delhi, helming the project, told HealthandMe.

Dr. Tripathi, who has trained with Dr. David K. C. Cooper, a British surgeon-scientist and pioneer of modern xenotransplantation, believes India could perform its first xenotransplant within six months of receiving government permission.

The push comes as xenotransplantation continues to make progress internationally. In 2025, a patient received a genetically engineered pig kidney and lived without dialysis for 271 days before subsequently receiving a human kidney transplant.

India recorded 20,138 organ transplants in 2025, ranking third globally. However, the gap between the demand for and supply of organs remains significant, with deceased-donor donations accounting for a small share of transplants.

Dr. Tripathi estimates India’s annual organ shortage at around 90,000. According to data reported by hospitals and transplant centers on the National Organ and Tissue Transplant Organization (NOTTO) National Registry Portal, the waiting list for major organs stood at 89,839 as of March 3, 2026.

Kidneys accounted for the largest share of patients on the waiting list, followed by livers, hearts, lungs and pancreases.

In an interview with HealthandMe, Dr. Tripathi, who is also working with Dr. Cooper at the Thomas E. Starzl Transplantation Institute in Pittsburgh, US, discussed the scientific barriers, infection risks, regulatory requirements and potential of xenotransplantation in India.

Also read: Pig Kidney Works In Human Body For 271 Days: Why Xenotransplants Could Bridge The Organ Transplant Gap

Q. A pig kidney functioned for 271 days without dialysis in a human. What does this milestone mean for xenotransplantation?

Dr. Shikhar Tripathi: Xenotransplantation has achieved significant milestones, but researchers are still working toward long-term viability. For now, it could serve as a bridge for patients who need an organ while researchers work to address complications and improve graft survival.

“Xenotransplantation has achieved some really significant milestones in the last year or so.”

Q. What are the main barriers to long-term survival of a transplanted animal organ?

Dr. Tripathi: Genetic engineering has helped researchers modify the pig genome to reduce the risk of early rejection. The challenge now is managing late complications, particularly in kidney xenotransplantation.

Two major concerns are proteinuria, or leakage of proteins through the kidney, and thrombotic microangiopathy (TMA), which involves injury to microscopic blood vessels.

“The current barrier we face is late complications of xenotransplantation.”

He added that his group has published research identifying potential pathways involved in proteinuria and TMA and is investigating ways to address these complications.

Read More: World Organ Donation Day 2026: Too Old Or Too Sick To Donate Organs? Doctors Bust Key Myths

Q. What are the infection risks associated with xenotransplantation, and why is lifelong monitoring important?

Dr. Tripathi: One concern is zoonosis, or the transmission of infection from an animal or animal organ to a human. Genetic modifications are intended to address this risk.

“There have been as many as 69 gene edits that have been done by eGenesis,” he said, referring to the company developing genetically engineered organs for transplantation.

Dr. Tripathi believes the risk of zoonotic infection is minimal, but this does not eliminate the risk of infection. Patients also face infections associated with immunosuppression, which is used to prevent their immune systems from rejecting a transplanted organ.

Dr. Tripathi’s group is also working toward accommodation and tolerance, which could allow transplanted organs to function with less immunosuppression.

He said lifelong monitoring of recipients will be needed to track outcomes and ensure continued medical care.

Q. India continues to face a significant organ shortage. How could xenotransplantation help bridge the gap between demand and supply?

Dr. Tripathi: India’s annual organ shortage is around 90,000, and it is increasing. The challenge is not just finding donors but ensuring they are medically fit and compatible with recipients.

He recalled a case in which an 85-year-old father-in-law was willing to donate a kidney to his daughter-in-law, but his age made him unsuitable, and no other family member was a match.

“The question is not whether you have a donor available. It’s also whether your donor is healthy or not,” he said.

He also raised ethical concerns about dependence on deceased-donor organs, arguing that patients should have alternatives that do not depend on another person’s death.

“I think xenotransplantation is not just going to solve a medical problem. It’s going to solve a moral problem,” he said.

READ: India Records 20,138 Organ Transplants In 2025; Deceased Donor Transplants Reach 3,526

Q. What is Sir Ganga Ram Hospital doing to advance xenotransplantation in India?

Dr. Tripathi: The aim is to carry out the first procedure with scientific support and within the necessary legal and ethical framework.

The team is prepared to move forward once the required guidelines are established and government permission is granted.

Q. How soon could India perform its first xenotransplant, and which type of transplant might reach clinical practice first?

Dr. Tripathi: I believe pancreatic islet-cell xenotransplantation could reach clinical practice before whole-organ transplantation.

Islet cells in the pancreas produce insulin, making them a potential area of research for conditions such as type 1 diabetes.

“It’s my scientific belief that islet-cell xenotransplantation would be the first one to hit the clinics,” he said.

As for India’s first xenotransplant, the timeline depends on government approval. “Potentially, six months from the day of the permission, we can perform the first transplant,” he said.

Q. What scientific, regulatory and biosecurity hurdles must India overcome before its first xenotransplant, and what lessons does the 1997 pig-organ transplant case involving Dr. Dhaniram Baruah in Assam offer today?

Dr. Tripathi: India’s first xenotransplant will have scientific, legal and ethical backing, along with patient consent. He said there was no comparison with the 1997 case involving Dr. Dhaniram Baruah in Assam, in which the patient died seven days after the procedure following multiple infections.

“We will not take a single step out of the legal ambit or the ethical ambit,” he said.

Q. Looking ahead five years, could India become a global leader in xenotransplantation?

Dr. Tripathi: India could play a leading international role. “India will be one of the leaders,” he said.

India can also establish its own xenorgan facilities over the next five to eight years. Until then, transporting organs from overseas companies could be an option, provided a secure transportation system is established in coordination with government authorities.