The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

Constipation is one of the most common digestive complaints affecting people of all ages. It is generally defined as having fewer than three bowel movements per week, passing hard stools, excessive straining, or a feeling of incomplete evacuation.

While occasional constipation is usually not a cause for concern and can often be managed through lifestyle changes, persistent or severe constipation may sometimes indicate an underlying health condition that requires medical attention.

Common Causes of Constipation

Several factors can contribute to constipation, including inadequate fiber intake, insufficient water consumption, lack of physical activity, stress, changes in routine, and certain medications. In many cases, improving dietary habits and maintaining an active lifestyle can help restore normal bowel function. However, when constipation becomes chronic or is accompanied by other symptoms, it should not be ignored.

Warning Signs

One of the most important warning signs is a sudden change in bowel habits, particularly in adults over the age of 50. Persistent constipation associated with unexplained weight loss, loss of appetite, fatigue, abdominal pain, bloating, or blood in the stool may indicate a more serious condition, such as colorectal cancer. Early detection is crucial, making timely medical evaluation essential.

What's Behind Chronic Constipation

Chronic constipation may also be linked to several medical disorders. Conditions such as hypothyroidism, diabetes, Parkinson’s disease, multiple sclerosis, and certain neurological disorders can affect the normal movement of the intestines. In some individuals, constipation may result from pelvic floor dysfunction, where the muscles involved in bowel movements do not coordinate properly.

Irritable Bowel Syndrome (IBS), particularly the constipation-predominant type, is another common cause of ongoing bowel difficulties. Inflammatory bowel diseases, intestinal narrowing, or bowel obstruction can also present with severe constipation and abdominal discomfort.

Many people rely on over-the-counter laxatives for relief. While these medications can be effective when used appropriately, long-term or excessive use without medical supervision may mask an underlying problem and can sometimes worsen bowel function over time.

How To Maintain Good Digestive Health

To maintain good digestive health, individuals should consume a fibre-rich diet that includes fruits, vegetables, whole grains, and legumes. Adequate hydration, regular exercise, and responding promptly to the urge to pass stools are equally important.

Constipation is often harmless, but persistent symptoms should never be dismissed. If constipation lasts for several weeks, becomes increasingly severe, or is associated with alarming symptoms such as bleeding, significant weight loss, or severe abdominal pain, seeking medical advice is essential. Recognizing these warning signs early can help identify serious health conditions and ensure timely treatment.

(By Dr. Pradeepta Kumar Sethy, Director Gastroenterology, Manipal Hospital EM Bypass & Mukundupur)

Yoga may offer benefits beyond flexibility and stress relief, with doctors from the All India Institute of Medical Sciences (AIIMS), New Delhi, ahead of International Yoga Day 2026, saying that studies have shown the ancient practice could help improve outcomes in conditions ranging from unexplained male infertility to autoimmune disorders such as rheumatoid arthritis and fibromyalgia.

This year marks the 12th International Day of Yoga, observed annually on June 21. The theme for this year, "Yoga for Healthy Ageing," highlights the practice's potential to enhance mobility, balance, flexibility, and mental well-being, helping people maintain health and independence at every stage of life.

Yoga And Unexplained Male Infertility

Dr. Rima Dada, Professor at the Laboratory for Molecular Reproduction and Genetics, Department of Anatomy, AIIMS Delhi, told HealthandMe that cases of unexplained male factor infertility have increased in recent decades. In many of these cases, standard sperm parameters appear normal, but sperm cells are affected by oxidative stress and DNA damage.

According to Dr. Rima, studies conducted in men with unexplained infertility found that regular yoga practice reduced oxidative stress, decreased sperm DNA damage, and normalized the expression of genes critical for early embryonic development. These benefits, however, generally require consistent practice for more than six months.

Also read:International Yoga Day 2026: 10 Desk Yoga Poses That Can Undo Hours of Sitting

Dr. Rima described yoga as an “art of living” that combines

• mindful asanas,
• relaxation techniques,
• pranayama,
• meditation,
• healthy nutrition,
• adequate sleep.

According to her, such lifestyle measures may improve sperm DNA quality, motility, and overall reproductive health while potentially reducing the burden of genetic and epigenetic disorders in future generations.

Yoga And Rheumatoid Arthritis

Dr. Rima also highlighted the role of yoga in rheumatoid arthritis, an autoimmune disease that typically affects small joints initially and may later involve larger joints as well as organs such as the lungs, heart, and brain.

She described yoga as an "art of living" that should be incorporated into daily life through mindful asanas, relaxation techniques, pranayama, meditation, a whole plant-based diet, and adequate sleep.

Read More: Trying to Quit Tobacco? Yoga Could Improve Your Chances, Suggests Study

She added that research has shown that yoga, including asanas, pranayama, and meditation, can help reduce inflammatory cytokines linked to swelling, pain, stiffness, and joint damage. Pranayama practices such as Anulom Vilom, Bhramari, and Ujjayi were highlighted as particularly beneficial.

For people living with rheumatoid arthritis, she recommended beginning with gentle loosening exercises under the supervision of a trained yoga therapist and avoiding strenuous postures during acute flare-ups. Pranayama and meditation, she said, may help reduce inflammation, improve emotional resilience, and support longer periods of remission.

Yoga As An Adjunct Therapy

Dr. Uma Kumar, Head of the Department of Rheumatology at AIIMS New Delhi, explained that autoimmune diseases occur when the immune system mistakenly attacks the body’s own tissues and organs.

Conditions such as rheumatoid arthritis, systemic lupus erythematosus, Sjogren’s syndrome, myositis, antiphospholipid antibody syndrome, and IgG4-related disease can significantly affect quality of life, often leading to pain, fatigue, depression, sleep disturbances, and reduced mobility.

“All these components are improved by yoga,” Dr. Kumar said.

However, she stressed that yoga should be viewed as an adjunct to medical treatment rather than a replacement. According to her, yoga may complement conventional therapies by improving sleep, flexibility, mental well-being, lifestyle habits, and overall quality of life.

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Yoga's Benefits For Fibromyalgia

Dr. Renu Bhatia, Additional Professor in the Department of Physiology at AIIMS Delhi, said supervised yoga therapy may help improve physical activity, sleep quality, muscle blood flow, pain levels, and flexibility in people with fibromyalgia.

The experts described fibromyalgia as a condition characterized by widespread pain despite normal laboratory findings and the absence of obvious inflammation.

Dr. Renu noted that studies have shown six weeks of supervised yoga intervention can reduce tender points while improving sensory symptoms, brain function, and neural excitability. However, she cautioned that yoga should be practiced under supervision, as excessive joint movement may aggravate symptoms in some patients.

Sickle cell disease (SCD) is one of India’s most pressing inherited blood disorders, with an estimated 1 in 86 births among tribal and disadvantaged groups affected.

Despite advances in diagnostics and treatment, families continue to face uncertainty, stigma, and limited awareness.

Why Genetic Counselling Matters

A crucial distinction often overlooked is between sickle cell trait (SCT) and sickle cell disease. Carriers with one gene are usually healthy but can pass the trait to their children, while those with two defective genes live with lifelong complications.

When both parents carry SCT, each child has a 50% chance of inheriting the trait and a 25% chance of developing the disease. This is why genetic counselling must be recognized as an integral part of the care continuum.

Genetic counselling provides clarity on inheritance patterns, transmission risks, and reproductive choices. In high-prevalence communities, it serves as a preventive strategy. Counselling is equally vital after diagnosis, guiding parents on managing complications, navigating education and employment, and preparing adolescents to understand their carrier status before marriage.

Also read: Sickle Cell Disease: Why India Must Add Curative Treatment to Meet Its 2047 Elimination Goal

The Role of National Sickle Cell Anemia Elimination Mission

India’s National Sickle Cell Anaemia Elimination Mission (2023) prioritizes screening in high-burden states, with clear objectives:

• to provide affordable, accessible, and quality care to all SCD patients;
• reduce prevalence through awareness campaigns and premarital genetic counselling;
• conduct targeted screening and early detection using validated Point-of-Care Testing (POCT) kits;
• ensure holistic management through primary, secondary, and tertiary healthcare facilities;
• enable community involvement by linking patients with social security schemes.

Embedding counselling into primary healthcare ensures every positive test is followed by culturally sensitive, professional support.

Sickle Cell Disease: Tackling Stigma and Misconceptions

SCD is often misinterpreted as a curse or lifestyle issue, leading to stigma and blame. Such misconceptions not only deepen emotional distress but also delay timely medical intervention. Genetic counselling reframes the condition as a scientifically understood, inherited disorder, shifting the narrative from superstition to evidence-based care.

By normalizing dialogue, it drives empathy-centered healthcare conversations and strengthens community resilience.

SCD is also often misinterpreted as a curse or lifestyle issue, leading to stigma and often blame. Such misconceptions not only deepen emotional distress but also delay timely medical intervention.

Genetic counselling reframes the condition as a scientifically understood, inherited disorder, shifting the narrative from superstition to evidence-based care. By normalizing dialogue, it encourages empathy-driven healthcare conversations and strengthens community resilience.

Sickle Cell Disease: Why Genetic Counseling Is Important

Sickle cell care cannot stop at diagnosis; counselling must accompany patients across every life stage from childhood through adolescence, marriage, pregnancy, and adulthood. This continuity transforms care from reactive to proactive, ensuring families are never left alone in their journey.

At the same time, awareness, education, and collaboration among clinicians, policymakers, patient groups, and communities are essential. Genetic counselling serves as the bridge between science and lived experience, enabling informed choices, reducing stigma, and promoting compassionate care that strengthens both families and the wider community.

(The author is Dr Manisha Madkaikar, Director - ICMR-National Institute for Research on Blood and Immune Disorders – Mumbai).