The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

Smoking has long been recognized as one of the most preventable causes of disease and early death worldwide. It plays a major role in heart attacks, strokes and several chronic illnesses. While public health messaging often focuses on how much a person smokes, new research suggests that when someone starts smoking may be just as important for long-term health.

A large nationwide study published in Scientific Reports analyzed health data from over nine million adults in South Korea. The findings were striking. People who began smoking before the age of 20 faced a significantly higher risk of stroke, heart attack and early death compared to those who started later, even if their total lifetime smoking exposure was similar.

Smoking Before 20: Why the age matters

Traditionally, doctors and researchers estimate smoking-related harm using pack-years, which combines the number of cigarettes smoked per day with the number of years a person has smoked. While this remains useful, the new study highlights an important gap. Two people with the same pack-years may not have the same health risks if one started smoking much earlier in life.

The researchers found that early starters had a much higher risk of stroke and heart attack than those who took up smoking after the age of 20. This suggests that the body may be especially vulnerable to tobacco damage during adolescence and early adulthood, making age of initiation an independent risk factor.

Smoking and stroke: what we already know

The link between smoking and stroke is well established. Long-term studies, including the famous Framingham Heart Study, have consistently shown that smokers are far more likely to experience a stroke than non-smokers. The risk increases with the number of cigarettes smoked and affects people across age groups.

Smoking damages blood vessels, speeds up plaque build-up in arteries, raises blood pressure and makes blood more likely to clot. All of these changes increase the chances of both ischaemic and haemorrhagic strokes. Younger adults who smoke are not protected simply because of their age, and in many cases, their relative risk is even higher.

Key findings from the Korean cohort

The study followed participants for nearly nine years using data from a mandatory national health screening programme. Researchers looked at stroke, heart attack, combined cardiovascular events and overall death rates.

Those who started smoking before 20 had about a 78 percent higher risk of stroke compared to non-smokers, especially when they also had high smoking exposure. Early starters also showed a much greater risk of heart attacks and combined cardiovascular events. Importantly, they had a higher risk of death from all causes, not just heart-related conditions. These patterns were consistent across men and women and across different metabolic health profiles.

Why early smoking causes greater harm

There are several reasons why smoking at a younger age may be more damaging. During adolescence, the heart, blood vessels and brain are still developing, which may make them more sensitive to toxins in tobacco smoke. Starting early is also linked to stronger nicotine dependence, making quitting harder and often leading to longer periods of smoking.

Early exposure may also trigger lasting inflammatory and metabolic changes in the body. These changes can increase stroke risk later in life, even when total cigarette exposure appears similar on paper.

What this means for public health

The findings send a clear message. Preventing smoking during adolescence could significantly reduce the future burden of stroke and heart disease. School-based education, strong warning messages and policies that limit youth access to tobacco remain critical.

Delaying smoking initiation, even by a few years, may have lifelong benefits. With cardiovascular diseases already among the leading causes of death globally, protecting young people from tobacco use is not just about avoiding addiction. It is about safeguarding their long-term health.

A simple tennis ball might be able to tell you whether you have dementia or not. While it sounds strange, experts explain that the strength of your hands is a major clue for how well your mind is aging.

In a recent video, Neurologist Dr. Baibing Chen explains that your grip strength is a "window" into your cognitive health. To squeeze your hand, your brain must coordinate nerves, muscles, and blood flow all at once. When this system weakens, it often suggests that the brain’s "resilience" or ability to bounce back is also lower.

While weak hands don't cause dementia, they can be an early warning sign. In some conditions, like vascular dementia, physical changes like slowing down or dropping things often happen before memory loss even begins.

How To Do The Tennis Ball Test At Home?

You don't need expensive equipment to check your strength. You can use a standard tennis ball or a stress ball to track your progress:

Get Ready: Sit up straight with your feet flat on the floor and your arm stretched out in front of you.

Squeeze: Grip the ball as hard as you possibly can.

Hold: Try to keep that strong squeeze for 15 to 30 seconds.

Repeat: Do this three times with each hand and note if you feel tired or if your strength fades quickly.

What the Numbers Mean

Researchers have found that people in the bottom 20% of grip strength have a much higher risk of developing memory problems.

For example, a massive study of nearly 200,000 adults showed that as grip strength drops, the risk of dementia goes up by about 12% to 20%.

Specifically, if a man’s grip strength is below 22 kg or a woman’s is below 14 kg, doctors consider that a "red flag" for future cognitive decline. These numbers are helpful because they show changes in the body years before memory loss actually starts.

What If You Fail The Tennis Ball Dementia Test?

It is very important to remember that a weak grip is not a guarantee of dementia. Many factors, such as arthritis, old injuries, or general lack of exercise, can cause your hands to feel weak.

The goal of this test is not to scare you, but to encourage you to be proactive. If you feel like your hands are getting "tired" faster during daily chores or you are dropping items more often, mention it to your doctor. They can help determine if it is just a muscle issue or something that needs more investigation.

How Is Dementia Diagnosed?

Dementia is one of the most common cognitive conditions in the world. According to the World Health Organization, there were 57 million people living with dementia in 2021, many of whom never had any treatment for it.

Early detection of dementia is an important part of the treatment. While it may not completely cure the disease, it can slow down the progress to help people retain as much of their abilities as possible.

Finding out if someone has Alzheimer’s is not as simple as taking one single test. Doctors act like detectives, gathering many different clues to figure out what is happening in the brain. To make an accurate diagnosis, healthcare providers use a combination of different tools and tests:

Brain Scans

Doctors may use imaging tests like MRI, CT, or PET scans to look at the physical structure of the brain and check for any unusual changes.

Cognitive Tests

There may be cognitive tests that check your recall skills. These are mental puzzles or questions that check your memory, problem-solving skills, and how well you can perform daily tasks.

Lab Work

This can also include blood tests or checking "spinal fluid" to look for specific markers that show up in people with certain types of dementia.

Physical Exams

A neurologist may also check your balance, your senses, and your reflexes to see how well your nerves are working.

Claire Danes recently revealed that she was shocked to learn that she was pregnant with her third child at 44. In an interview with Amy Poehler in an episode of Good Hang with Amy Poehler, the Beast In Me actress revealed that she burst into tears at her OB/GYN’s office, explaining that she didn’t know it was possible to be pregnant after 40.

Danes shared that she initially felt a strange sense of embarrassment about the pregnancy. Because she and her husband, Hugh Dancy, weren’t planning for a third, Danes felt like she had stepped outside of normal "parameters."

The debate surrounding pregnancies after 40 has always persisted. Many people like Claire believe that it is impossible to get pregnant after your biological clock runs out. However, in reality, things do not work like that. Dr Rohan Palshetkar, Consultant IVF specialist, at Bloom IVF explains a few factors one should know about.

Can You Get Pregnant After 40?

Yes, Dr Rohan explains that it is completely possible and safe with the current technological advancements. “Earlier we did have fetal medicine specialists, high resolution ultrasounds, better monitoring techniques and safter IVF options”

Screening tests are much more detailed, IVF options are more robust and egg freezing is also an empowering tool for women who wish to have pregnancies later in life, Dr Rohan explained.

However, he also pointed out that post 35 risks of having diabetes and hypertension increases, so consistent monitoring helps a lot.

What Are Some Risks Of Pregnancies After 40?

The chance of having a high-risk pregnancy increases for women above 40, according to the American College of Obstetricians & Gynecologists (ACOG). They explain that since women are born with all the eggs they will ever have, those eggs age right along with the body. As time goes on, the number of eggs decreases, and their quality can change.

While many women have healthy pregnancies in their 40s, here are some specific risks you should know about.

Chromosome Issues

Older eggs are more likely to have certain genetic changes. This means there is a higher chance for the baby to be born with a health condition like Down syndrome instead.

Miscarriage or Stillbirth

Women in their forties face a much higher statistical chance of losing a pregnancy. It is very important to stay in close contact with your doctor to monitor your baby's health.

Low Birth Weight

There is a greater risk that the baby will be born weighing less than what is considered healthy. Small babies often need extra medical care and stay in the hospital longer.

Blood Clots

Being pregnant naturally increases your risk of developing dangerous blood clots. However, this specific medical danger becomes even more likely for mothers who are over the age of thirty-five or forty.

Gestational Diabetes

This is a specific type of high blood sugar that some women develop only while they are pregnant. It requires careful diet management or medication to keep you and baby safe.

Preeclampsia

This is a very serious condition involving high blood pressure that can happen during pregnancy. It can be dangerous for the mother and the baby if it is not treated quickly.

Labor Challenges

Delivery can be more difficult for older mothers, often leading to longer labor times. Because of these complications, doctors are much more likely to recommend a surgical C-section birth instead.

How Doctors Support Pregnancies After 40

Being "high-risk" doesn’t mean something will go wrong; it just means your medical team will watch you more closely. Modern medicine has great tools to keep you and your baby safe, such as,

• Prenatal Screening
• Extra Ultrasounds
• Frequent Check-ups