The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

As bird flu continues to trouble several countries, health officials in the United States have reported the first known human case of the H5N5 subtype of avian influenza. The Washington State Department of Health announced on November 14, 2025, that the virus was found in a resident of Grays Harbor County.

The patient, an older adult with existing medical issues, is currently in the hospital. Authorities noted that the individual kept poultry at home that had contact with wild birds, which is believed to be the likely source of the infection, though the investigation is still underway. Since H5N5 is newly identified in humans, many are asking whether it differs from the earlier H5N1 strain.

What Is the H5N1 Strain?

H5N1 is a highly pathogenic form of avian influenza that mainly affects birds but can also infect mammals, including humans. It can lead to severe illness in people and has a high fatality rate, though it rarely spreads from one person to another, as per the World Health Organization. The virus has moved across continents in wild and farmed birds and has recently been found in dairy cattle and several other mammals.

What Is The New H5N5 Strain?

The “new” H5N1 strain refers to the 2.3.4.4b clade of highly pathogenic avian influenza (HPAI), which has caused a widespread animal outbreak since appearing in 2020. This version is a newer genetic branch of H5N1 and has swept through wild birds, poultry farms and an increasing range of mammals, including dairy herds in the United States. At present, the patient infected in the U.S. has been diagnosed with the newer H5N5 subtype.

How Is H5N5 Different From H5N1?

According to the CDC, both H5N5 and H5N1 fall under the avian influenza family, with the main distinction being the type of neuraminidase (N) protein on the virus surface. H5N5 contains the N5 protein, while H5N1 carries the N1 protein. Although this genetic change can influence viral features, their overall pattern of illness and symptoms is expected to be much the same, particularly in birds and livestock.

The genetic structure is the only difference, with H5N1 strain containing a subtype of influenza A with a segmented genome while the other has a new reassortant virus formed from several subtypes, possibly including H5N1, as per National Institute of Health.

Is A Vaccine Available For The H5N1 Bird Flu Strain?

Vaccines for bird flu do exist, but they are not intended for general public use and are not easily available for everyday protection. Some vaccines have been created and stored for possible deployment in people at higher risk, such as poultry workers and farm staff, and they are also used in animals like chickens to help manage outbreaks. The United States and several other countries have stockpiled H5N1-specific vaccines that could be rolled out if the threat to humans grows. A few nations, including Finland, are already offering them to certain high-risk groups. At the moment, there is no advice for the wider public to take a bird flu vaccine, as there is no sustained human-to-human spread and no mass-market human vaccine in use.

Flu season is here again and global health experts are getting worried about a strain that came up in June. The worry's cause is that the strain came up four months after the makeup of this year's flu shot.

This is the strain H3N2. The strain has caused outbreaks in Canada and in the UK, and health officials have warned about the early wave that is sending people to the hospitals.

As per Dr Wenqing Zhang, who is the head of the World Health Organization (WHO)'s Global Respiratory Threats Unit, "Since it emerged, it is rapidly spreading and predominating in some countries so far in the Northern Hemisphere."

The New Strain

The version of H3N2, which has been circulated worldwide this year "acquired 7 new mutations over the summer," said Antonia Ho, a consultant in infectious disease at Scotland's University of Glasgow. As per her media statement, this "means the virus is quite different to the H3N2 strain included in this year's vaccine".

The strain is now picking up in Canada, after it has been active in the UK, leading to flu cases being triple to what it was the same time last year. Furthermore, generally, H3N2 is thought to cause more illness, and this could be worse for older adults. In fact, Japan is also experiencing an early and harsh flu season. Japanese news outlet Nippon TV reported that as of November 4, flu cases in Tokyo has surged six times to the level it had seen last year. This data has been confirmed by the Japanese Ministry of Health, Labor, and Welfare. As per the media outlet, more than 2,300 day cares and schools were partially closed.

What Is Happening In The US?

H3N2, which is a strain of influenza have had some cases in the US, where people reported positive for flu. However, the Centers for Disease Control and Prevention (CDC) has not provided any detailed national report on flu since September 26, ever since the government shutdown happened.

What About This Year's Flu Shot? Will It Be Of any Use?

Every February, global health experts and vaccine manufacturers decide which flu strains should be included in the Northern Hemisphere’s fall vaccine, based on the strains circulating in the Southern Hemisphere. This year’s flu shot targets three strains, two influenza A types and one influenza B.

While the annual flu vaccine doesn’t always prevent infection, it significantly reduces the severity of illness. Last year, it was up to 55% effective in preventing hospitalizations among adults with the flu.

On Tuesday, U.K. health authorities reported early data showing that this year’s vaccine is up to 40% effective at preventing hospitalizations in adults.

Despite the variation in effectiveness, experts stress the importance of getting vaccinated. “Decades of data show that even when the match isn’t perfect, the flu shot continues to prevent hospitalizations, ICU admissions, and helps keep people out of the cemetery,” said Dr William Schaffner, an infectious disease expert at Vanderbilt University Medical Center, in Nashville, Tennessee, as reported by NBC.

As of 7am today, Delhi's average AQI was registered at 446 as per aqi.in. However, the Early Warning System for Delhi, under the Ministry of Earth Sciences, Delhi's average AQI at 7am was registered at 341, slightly better, still close to 400. Dr Shivanshu Raj Goyal, a pulmonologist and Associate Director Pulmonary Medicine at MAX Healthcare in Gurugram and Delhi, in an Instagram video said that breathing this toxic air is equivalent to smoking 20 cigarettes in a day.

No One In Delhi Is A Non Smoker

The doctor starts his video with a rather strong statement, "At present, no one in Delhi-NCR is a non-smoker."

"With the AQI of around 400, if I break down the facts, with every 20 of an AQI of PM2.5, is equivalent to smoking a cigarette. So at the AQI of around 400, you are smoking easily 20 cigarettes a day. That is for everyone, each one of us, even a small change. So imagine the amount of damage that this AQI must be causing to your lungs," he says.

The doctor also states that on an average, a person breathes around 20,000 times in a day, so it means we are inhaling the toxic air at least 20,000 times a day.

As per Action on Smoking and Health (ASH), a cigarette contains nicotine, and tar, which is composed of chemicals like benzene, benzopyrene, and the gas includes carbon monoxide, ammonia, dimethyl nitrosamine, cadmium, formaldehyde, hydrogen cyanide and acrolein. Some of these marked irritant properties are also carcinogen, meaning, it can cause cancer.

Whereas Air Pollution contains pollutants like particulate matter PM 10 and PM 2.5, ozone, nitrogen dioxide, carbon monoxide, cadmium and sulfur dioxide. Air pollution, which is often a byproduct of combustion or released from vehicle exhaust also contain formaldehyde, benzopyrene, and benzene. As per the World Health Organization (WHO), the pollutants contain carcinogens, and the outdoor air pollution is in fact classified as Group 1 carcinogen.

Common Carcinogen In A Cigarette And Air Pollutants

Carbon Monoxide: a poisonous, flammable gas that is colorless, odorless, tasteless, and slightly less dense than air.

Benzene: a colorless and highly flammable liquid with a sweet smell, and is partially responsible for the aroma of gasoline.

Cadmium: a soft, silvery-white metal (atomic number 48) that is toxic and naturally found in the environment, but human activities have increased its levels. It is used in products like batteries, pigments, and coatings, and exposure can occur through tobacco smoke, contaminated food, and occupational inhalation. Cadmium is a known human carcinogen that can damage the kidneys and bones.

Formaldehyde: a colorless, flammable gas with a strong odor, whose exposure could cause cancer.

Benzopyrene: a group of organic compounds known as polycyclic aromatic hydrocarbons. It is a colorless crystalline solid found in sources like cigarette smoke, coal tar and is a known carcinogen that can cause cancer and other health problems like skin rashes and bronchitis, and exposure requires medical attention for any symptoms.

So, What Can Be Done To Protect Yourself Against These Carcinogen?

Dr Shivanshu Raj Goyal points out that these carcinogens could lead to long term lung and heart damage, as well ass cause chronic cough, breathlessness, asthma, and COPD. However, there are ways to protect yourself:

• Avoid outdoor activities during peak pollution hours
• Use N95 masks when stepping out
• Keep air purifiers on indoors
• Stay hydrated and include antioxidant-rich foods
• Visit a pulmonologist if you experience persistent breathing issues