The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

Ahead of Diwali festivities, Delhi is once again battling its annual air pollution crisis. The city's air quality index (AQI) - which measures PM2.5, fine particulate matter, has crossed 500 in some regions, entering the "hazardous" category, raising health concerns for millions in the capital.

The effects of air pollution are not just limited to physical health. Apart from your lungs and heart, long-term exposure to toxic air can render you feeling anxious, stressed, demotivated and mentally fatigued.

The reason behind this is not one-fold. The worsening of mental health due to air pollution is a culmination of many factors.

From particulate matter triggering inflammation and negatively affecting the body’s stress response to restrictions on outdoor activities, disturbance in sleep and lack of physical activity, air pollution contributes to mental health burden in many ways.

Dr Varsha Viswanathan, psychiatrist at Athulya Senior Care and Athulya Geriatric Care Hospital, Chennai, told HealthandMe that particulate matter in polluted air can enter the bloodstream and trigger inflammatory responses.

She explained, “This may lead to oxidative stress and affect brain functions involved in mood regulation, attention, memory and emotional processing. Over time, these changes may contribute to increased irritability, mood disturbances and difficulty managing emotional responses.”

Air Pollution & Stress

Also read: Climate Crisis Is A Health Crisis: Just 6 Actions Could Save 1.6 Million Lives, Says WHO

PM2.5, consists of tiny airborne particles that can penetrate into the lungs. Some can even enter the bloodstream and cause inflammation and oxidative stress. These effects may also affect the brain and its functions.

Cortisol is a hormone related to the body’s response to stress. Changes in stress regulation due to pollution may make it harder for some individuals to manage everyday challenges. Dr Viswanathan explains that air pollution may also affect the body’s stress-response system.

“Repeated exposure to environmental pollutants can affect the regulation of stress hormones such as cortisol. This may increase physiological stress and contribute to symptoms such as restlessness, heightened alertness, difficulty relaxing and persistent feelings of tension,” she says.

Air Pollution & Anxiety

Also read: Air Pollution In Delhi: Experts Warn Of Red Eyes, Itching, Watering In Children

Apart from stress, living in highly polluted cities can also cause one to feel constantly uncomfortable, uncertain and anxious. Kakul Faruqi, Senior Consultant Psychologist at LH Hiranandani Hospital, Mumbai, told HealthandMe that pollution can become a source of fear and withdrawal.

She said that someone who is prone to anxiety, breathing difficulty may be interpreted as a sign of immediate danger, which could trigger further fear and distress.

“Psychologically speaking, pollution can be a source of discomfort, fear and withdrawal. A coughing fit, trouble breathing and insomnia can exhaust an individual, making it more difficult for him or her to cope with daily stresses. An individual who is susceptible to panic attacks can experience fear and negative interpretations of physical symptoms due to trouble breathing,” Faruqi explains.

She also said that repeated exposure can also make the threat feel inescapable. Faruqi says that when individuals perceive pollution as a problem beyond their control, the resulting uncertainty can become extremely overwhelming.

Lack Of Outdoor Time May Contribute To Depression

Also read: Supreme Court Allows Green Crackers In Delhi-NCR Ahead Of Diwali: Are They Really Safe For Your Health?

Faruqi explains that pollution can make it harder to engage in behaviours that support psychological health.

When pollution levels are high, people normally avoid spending time outside socialising, exercising, walking, and spending time in green spaces. These activities often provide opportunities for physical movement, social connection and relaxation. Missing out on these activities can affect one emotional and mental well-being.

“The reduction in outlets for relaxation, in addition to experiencing feelings of loneliness and frustration, can lead to depression,” she says.

Dr Viswanathan also highlights how poor air quality can disrupt sleep, physical activity and normal social routines, which could further worsen mental well-being.

“Inadequate sleep and reduced physical activity can, in turn, affect emotional regulation, concentration and the ability to cope with everyday stress,” she says.

How To Protect Your Mental Health When AQI Is High?

When AQI is high, it is important to reduce exposure but at the same time, maintaining routines that help psychological well-being is also important. Faruqi recommends checking air quality in one’s locality, adjusting exercise habits accordingly and making an effort to preserve sleep and social interaction.

Some practical measures include:

• Adjust outdoor activities: Check local air quality levels and move exercise indoors when pollution is high. Avoid strenuous outdoor activity during severe pollution.

• Maintain physical activity: Indoor exercise can help preserve movement and routine when outdoor conditions are unsuitable.

• Protect sleep: Maintain regular sleep and wake times, and reduce indoor pollution where possible.

• Stay socially connected: Continue interacting with friends and family, even when outdoor meetings are difficult.

• Limit repeated pollution checking: Stay informed through reliable sources, but avoid continuously monitoring pollution levels without taking practical steps to reduce exposure.

• Seek professional support: Constant anxiety, depressive symptoms or difficulty carrying out everyday activities should not be ignored.

Faruqi advises that “if one experiences persisting anxiety, depression, or impairment in functioning, a visit to a mental health professional would be advisable.”

Novo Nordisk’s GLP-1 weight loss pill, Wegovy, has been approved in Australia for sale. An alternative to weekly weight loss injections, the Therapeutic Goods Administration (TGA) has cleared Wegovy, which contains semaglutide, the same active ingredient found in GLP-1 weight loss injections: Wegovy and Ozempic.

The pill received TGA approval on November 3, 2026, and is expecting to reach the shelves by Christmas.

It is prescribed to eligible adults to help manage chronic obesity along with lifestyle changes. It is also approved to reduce the risk of major cardiovascular events in eligible patients.

Until now, Australians seeking GLP-1 medication for weight management have primarily had access to injectable formulations. The tablet offers a different approach.

How Does The Wegovy Weight Loss Pill Work?

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The new tablet contains semaglutide, a GLP-1 receptor agonist that mimics the action of the naturally occurring glucagon-like peptide-1 hormone.

GLP-1 medications act on appetite regulation. They help users feel full, reduce cravings and slow stomach emptying, which can lead to lower calorie intake and weight loss.

Unlike injectable Wegovy, which is administered once a week, this tablet should be taken every day.

The TGA has approved four tablet strengths for sale: 1.5 mg, 4 mg, 9 mg and 25 mg. Treatment starts at a lower dose, which is gradually increased over approximately 16 weeks under medical supervision. The tablet also has specific use requirements. Patients must:

• Take it first thing in the morning on an empty stomach.
• Swallow it with a small amount of water.
• Avoid eating, drinking or taking other oral medications for at least 30 minutes afterwards.

The fasting instructions are important because semaglutide is absorbed less efficiently when taken orally. So following that instruction is crucial as a 25 mg tablet has to achieve an effect comparable to the 2.4 mg weekly injectable Wegovy dose.

Eligibility For GLP-1 Weight Loss Pill In Australia

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The TGA approval covers adults who meet specific weight-related criteria. These include:

• Adults with obesity, defined as a body mass index (BMI) of 30 or higher.
• Adults who are overweight, with a BMI between 27 and 30, and have at least one weight-related health condition.

These conditions may include high blood pressure, abnormal cholesterol levels, type 2 diabetes, fatty liver disease or other weight-related complications.

The medication is also approved to reduce the risk of major adverse cardiovascular events in eligible adults with cardiovascular disease and those who are overweight or obese but don’t have diabetes.

However, approval does not mean everyone meeting these criteria should automatically take the medication. A doctor must assess your health, medical history, and risks before prescribing it.

Dr Brendan Hanrahan, an obesity medicine specialist at Brisbane's Wesley Hospital, welcomed wider access to the medication, saying GLP-1 drugs have "lived up to and exceeded the hype". However, he questioned whether BMI alone is enough to determine eligibility.

He suggested waist circumference could offer some information about health risks, saying that some people may experience complications related to weight even when their BMI falls within the ‘normal’ healthy range.

Side Effects And Risks Of Wegovy

The oral pill does not eliminate the side effects associated with semaglutide. Common adverse effects include:

• Nausea
• Vomiting
• Diarrhoea
• Constipation
• Abdominal discomfort
• Headache
• Fatigue
• Dizziness

Gastrointestinal symptoms can sometimes lead to dehydration, which may increase the risk of kidney problems.

The TGA also warns about more serious complications, including acute pancreatitis and diabetic retinopathy. People with diabetes, particularly those with pre-existing eye disease, may need clinical monitoring.

Semaglutide is not recommended during pregnancy, and people planning to become pregnant should discuss treatment and timing with their doctor.

The TGA has also warned of depression and suicidal thoughts or behaviours linked with GLP-1 medications.

A breast cancer diagnosis can change more than a woman’s immediate health priorities. Suddenly, appointments, treatment decisions and medical advice become part of everyday life, alongside work deadlines, family responsibilities, relationships and personal plans. Even as women focus on getting better, questions about how treatment might affect their routines, independence and future can be difficult to navigate.

For women diagnosed with early breast cancer, treatment offers an opportunity to address the disease and reduce the risk of it returning. But the experience is about more than medical outcomes alone. How women feel during treatment, the support available to them and their ability to continue doing the things that matter to them are also important considerations.

Treating early breast cancer involves looking beyond the immediate diagnosis to understand what matters to each patient. While our priority is to recommend treatment that offers the best possible clinical benefit, it is equally important to discuss how treatment may affect everyday life, from managing side effects to maintaining relationships and planning for the future. By encouraging open conversations about advanced therapies and addressing patients’ concerns early, we can help women make informed decisions while supporting their quality of life throughout the treatment journey.

Here are four ways women can approach treatment while keeping their personal well-being in focus.

1. Make your everyday life part of the treatment conversation

Breast cancer treatment can affect everyday life in different ways, from recovery after surgery to managing side effects or making time for regular appointments. For women balancing work, family responsibilities and personal commitments, understanding what treatment involves can help them plan ahead and arrange the support they need.

Advances in breast cancer care have expanded treatment options for eligible patients, with some targeted therapies offering a more tailored approach that may help reduce certain treatment-related side effects. Understanding the potential benefits and impact of each option on quality of life can help women make informed decisions with their oncologist. Discussing how treatment may affect daily routines, energy levels and recovery can also help women plan for the journey ahead while continuing to prioritise what matters to them.

Also read: Unspoken Side Of Breast Cancer: Experts Discuss Recurrence Risk, Emotional Toll & Societal Impact At Times Health Summit 2026

2. Prepare for physical changes rather than waiting for them to become overwhelming

Breast cancer treatment affects every woman differently. Depending on the therapy, side effects may include fatigue, nausea, joint pain, sleep disturbances or changes in hair and weight, potentially making everyday activities more challenging.

Women should discuss potential side effects with their healthcare team and seek advice early on, as appropriate interventions can help manage symptoms. Gentle physical activity, a balanced diet and adequate rest may also support overall well-being, depending on individual needs and medical advice. The goal is to find a manageable routine that supports recovery and quality of life without putting every other aspect of life on hold.

3. Give emotional well-being, relationships and personal plans the same consideration

The emotional impact of breast cancer can be as significant as the physical effects. Uncertainty about the future, changes in body image and concerns about loved ones can affect emotional well-being. Talking to trusted friends, joining a support group or seeking professional guidance can help women navigate these challenges, while open conversations with family can make it easier to ask for support.

Personal concerns, including fertility, intimacy and sexual health, also deserve attention. Women should discuss these with their healthcare team before treatment begins, particularly when fertility preservation may be an option. Addressing these concerns early can help women understand their choices and ensure their emotional well-being and personal priorities remain part of the treatment journey.

Also read: Hot Flashes To Night Sweats: Leading US OB-GYN Group Updates Menopause Treatment Guidance After 12 Years

4. Keep the future in view while focusing on the present

Looking beyond initial treatment can help women prepare for the next stages of care. Depending on the cancer’s characteristics, doctors may recommend additional treatment to reduce recurrence risk, with some women continuing medication for several years. Understanding the purpose, expected benefits and duration of treatment can help women plan ahead.

Regular follow-up appointments remain important for monitoring recovery and addressing new symptoms or ongoing side effects. If treatment becomes difficult to manage, women should speak to their healthcare team, who may suggest ways to manage symptoms or explore suitable alternatives. Staying informed about the care plan can help women look ahead with greater confidence while prioritising their long-term health and quality of life.

Making room for the life beyond the diagnosis

An early breast cancer diagnosis can bring uncertainty, but it does not erase the other parts of a woman’s life. Work, relationships, family, personal ambitions and everyday pleasures remain important, even while treatment becomes a priority.

Making space for these aspects of life starts with asking questions, communicating concerns and seeking support before challenges become overwhelming. Clinical outcomes and recurrence risk remain important considerations, but so does the experience of living through treatment.

The goal is not to manage every aspect of the journey perfectly. It is to ensure that women have the information, care and support they need to navigate treatment in a way that considers both their health and their quality of life.

By Dr. Sachin Sekhar Biswal, Consultant Medical Oncologist, Manipal Hospital, Bhubaneswar