The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

In India, Pantop 40 has become almost a staple in many households, often consumed daily as casually as a multivitamin, particularly by those over 40. People frequently turn to it to manage acidity, often without considering the possible long-term consequences. What seems like a simple fix, however, can quietly lead to serious health issues. Recently, Dr. Shagun Agarwal, MBBS, M.S., FNB Joint Replacement, shared an advisory on Instagram highlighting the importance of limiting Pantop 40 use.

What Is Pantop 40 or Pantoprazole?

Pantoprazole is a medication designed to treat conditions caused by excessive stomach acid. It is commonly prescribed for erosive esophagitis or heartburn linked to gastroesophageal reflux disease (GERD), where stomach acid flows back into the esophagus. It can also be used for Zollinger-Ellison syndrome, a rare condition in which the stomach produces too much acid.

As a proton pump inhibitor (PPI), Pantoprazole works by lowering the amount of acid produced in the stomach. It is available only with a doctor’s prescription and comes in forms such as packets, delayed-release tablets, or powder for suspension.

Risks of Long-Term Pantop 40 Use

Many people in India rely on Pantop 40 regularly, often treating it as completely harmless. After the age of 40–50, taking it has almost become a routine, without fully appreciating the potential health risks.

Dr. Agarwal explains that using Pantoprazole for long periods can cause serious complications. It may lead to deficiencies in vitamin B12 and magnesium, weaken bones and increase the risk of fractures, inflame the kidneys, trigger digestive problems like IBS, and most concerningly, cause rebound acidity, where acid reflux becomes worse once the medication is stopped.

It is crucial to remember that Pantoprazole is only a temporary fix. While it reduces stomach acid, it does not address the root causes of acidity or other digestive issues. Relying solely on the drug may bring short-term relief, but it cannot replace the benefits of healthy lifestyle adjustments.

Pantop 40: Recommended Dosage

Dosage varies depending on the patient and condition. Follow your doctor’s instructions carefully. The following information reflects general guidelines:

For erosive esophagitis:

• Adults: 40 mg once daily for up to 8 weeks. In certain cases, your doctor may extend the duration.
• Children 5 years and older weighing 40 kg or more: 40 mg once daily for up to 8 weeks.
• Children 5 years and older weighing 15–39 kg: 20 mg once daily for up to 8 weeks.
• Children under 5 years: Use and dose must be determined by a doctor.

For Zollinger-Ellison syndrome:

• Adults: 40 mg twice daily initially, with possible adjustments as advised by the doctor.
• Children: Use and dose determined by a doctor.

Lifestyle Changes Are Key

Dr. Agarwal emphasizes that many people rely on Pantop 40 to avoid changing their habits. Small, consistent lifestyle adjustments can have a significant impact on acidity. Eating smaller meals, avoiding trigger foods like coffee, fried, or spicy items, having dinner 2–3 hours before bedtime, and losing 5–10% of body weight can reduce acidity by nearly half, often without the need for long-term medication.

In recent weeks, India’s air quality has taken a steep downturn, with “severe” pollution levels reported in cities such as Delhi, Gurugram, and others. Celebrity nutritionist and holistic wellness expert Luke Coutinho has issued a strong warning about the worsening air, calling it a public health crisis that is already affecting millions.

In a recent Instagram post, Luke admitted he is also struggling to cope with the toxic air—a feeling shared by many of his patients. “Dear citizens, this is more than a health issue; it’s a matter of social justice. Delhi’s air is a serious public health emergency, and parts of Mumbai are in poor to hazardous condition. This is a biological threat,” Luke stated in his post.

Air Pollution And PM2.5

Luke explains that the primary culprit is PM2.5, which are tiny particles can enter the bloodstream, bypassing the body’s natural defenses and causing inflammation. “This isn’t just about coughing. Long-term exposure increases the risk of heart disease, stroke, cancer, chronic lung disease, and even lung and brain damage in children,” he adds.

The good news is that research shows reducing exposure, improving nutrition, and training the lungs can lower inflammation by 20 to 40 percent, according to Luke. He also shares a guide to help families start protecting their lung health.

Luke Coutinho's Guide to Protecting Your Lungs

Foundation 1: Aggressive Exposure Reduction

To cut down exposure, the first step is to treat indoor spaces as your new outdoor environment. Avoid going out between 10 a.m. and 4 p.m., and check air quality indices like AQLin or SAFAR, especially keeping children indoors if the AQI is above 150. When stepping outside, wear a properly fitted N95 or KN95 mask to ensure 80–95 percent protection, as surgical masks are insufficient.

Indoors, treat air purifiers like essential medical devices. A HEPA purifier in the bedroom can reduce particulate matter by 50 to 70 percent, and it is important to replace filters regularly. Avoid incense, candles, and fireworks, and use a damp mop rather than sweeping to minimize dust.

Lastly, quit smoking entirely, as it compounds the lung damage caused by pollution. Reducing exposure is the single most effective step and can slow lung decline by up to 30 percent.

Foundation 2: An Anti-Inflammatory Nutrition Plan

A diet rich in anti-inflammatory, high-antioxidant foods can reduce pollution-related damage by as much as 35 percent. Include two cups of leafy greens like spinach, kale, and Swiss chard daily, which can be added to smoothies or soups. Add one to two cups of steamed cruciferous vegetables such as broccoli, cabbage, and cauliflower; quick steaming is better than boiling.

Consume two to three servings of antioxidant-rich fruits like guava, apples, and strawberries, with guava highlighted as an excellent source of vitamin C. Include one cup of carotenoids or lycopene from foods like carrots and tomatoes, noting that cooking tomatoes with a little oil improves absorption.

Get omega-3 fats from two to three servings of fatty fish per week or one handful of nuts and seeds daily, such as salmon, walnuts, or flaxseeds, which support heart health. Limit processed sugars, refined carbs, excess salt, and deep-fried foods to under 10 percent of total calories, as they promote inflammation. Stay well-hydrated with two to three liters of water daily to thin mucus and support the lungs’ natural cleansing processes.

Foundation 3: Evidence-Based Supplements

Luke suggests remembering key supplements with the code CODE-Z: C for vitamin C, O for omega-3s, D for vitamin D, E for vitamin E, and Z for zinc. Vitamin C (500–1000 mg/day) from guava and strawberries acts as a powerful antioxidant for the lungs. Omega-3s (EPA/DHA) from salmon or walnuts (1000–2000 mg/day) help reduce inflammation from pollution.

Vitamin D (2000–4000 IU/day), found in cod liver oil and fortified milk, supports immunity and lowers infection risk. Vitamin E (200–400 IU/day) from sunflower seeds and almonds protects lung cells with fat-soluble antioxidants. Supplements are helpful during acute pollution exposure, but food should remain the primary source of nutrients. It is important to take supplements under professional guidance, cycle them every 2.5 months, and consult a doctor before starting any new regimen, especially for children.

Foundation 4: Respiratory Resilience with Breathing Exercises

To strengthen the lungs, practice targeted breathing exercises and maintain humidified air. Pursed-lip breathing involves inhaling for two to four seconds and exhaling for four to six seconds through pursed lips; practicing this for five minutes twice daily can ease breathlessness.

Diaphragmatic breathing strengthens the main breathing muscle, allowing for deeper and more efficient breaths. Additionally, five minutes of steam or humidified air daily keeps airways moist and helps clear mucus, supporting overall respiratory resilience.

But remember, always keep your doctor informed before starting any new supplements or changing your diet, especially for children or if you have an existing health condition. Don’t ignore early warning signs, like persistent cough, fatigue, or shortness of breath, which should be checked promptly. Above all, focus on minimizing your exposure to polluted air first.

Melatonin use has increased around the world as people grow more aware of sleep health and seek quick solutions for restless nights. The market now includes both standalone melatonin tablets and mixed formulas combined with calming plant extracts. Many doctors, however, are urging caution, warning that daily use may not be as safe or effective as people assume.

Why Are Doctors Warning Against Daily Melatonin Use?

A few years ago, pediatric sleep specialist Dr Judith Owens began noticing something unusual in her clinic. Owens, who teaches neurology at Harvard Medical School and works at Boston Children’s Hospital, has spent decades treating children who struggle to sleep. What startled her was how many of them were now taking melatonin. She explains that in most cases parents had already tried the supplement before seeking medical help, a sharp change from what she saw earlier in her career.

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As per TIMES, adults have followed a similar path. Between 1999 and 2018, the number of people in the United States using melatonin rose more than fivefold. Because it is sold as a supplement, companies can promote it as a harmless, natural sleep helper without formal review by the U.S. Food and Drug Administration. Yet major sleep groups, including the American Academy of Sleep Medicine, do not recommend melatonin as a treatment for insomnia. Researchers continue to stress that its long-term impact remains uncertain.

How Much Melatonin Is Too Much

As night approaches, the pineal gland begins to release melatonin into the bloodstream. Levels rise through the night and decline after sunrise, helping the body understand the length of darkness and adjust internal functions accordingly.

Researchers have learned that melatonin’s reach extends beyond sleep. It influences immune activity, inflammation, and even the programmed death of cells. As per TIMES, experiments show that several tissues produce small amounts of melatonin on their own, and a wide range of cells carry receptors that respond to it.

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Disturbances in melatonin rhythms have been found in conditions such as depression, bipolar disorder, Type 2 diabetes, schizophrenia, some cancers, and Alzheimer’s disease.

Interestingly, melatonin can be helpful when used under medical direction. Blind individuals with disrupted circadian cycles often benefit from carefully timed doses. Children with autism may sleep better with prescribed melatonin, and scientists have explored whether it could aid recovery after heart attacks.

Melatonin And Heart Failure: Is There A Link?

Despite these potential uses, most people take melatonin in ways that do not match how doctors view the hormone. Since large clinical trials are limited, some researchers have turned to electronic health records to spot trends.

One recent abstract, presented at an American Heart Association meeting, examined adults who were prescribed melatonin and took it for at least a year. These individuals had a markedly higher rate of heart failure compared with similar patients who did not take melatonin. The study sparked attention, though specialists caution against assuming that melatonin caused the problem. Insomnia and heart disease often coexist, so the need for melatonin may simply reflect early signs of heart trouble.

Is Melatonin Bad For You?

Many experts believe that the main issue is the lack of long-term data. Doctors still cannot say whether regular supplementation weakens the body’s own melatonin production. Owens is especially concerned about children who take melatonin nightly for long stretches. Melatonin influences bone growth, immune function, and reproductive development, which raises questions about possible effects later in life.

Some evidence offers reassurance. A Dutch research group followed children with ADHD and other diagnoses who were on medically supervised melatonin for nearly four years. They did not see harmful outcomes. Still, these children were monitored closely and given doses tailored to their needs. Without such oversight, adults and children may easily take more than required, disrupting the body’s internal clock and worsening sleep.

Metabolism also differs from person to person. A dose that is modest for one individual may linger in another’s system well into the morning.

Melatonin Use: Long Term Effects

Both Owens and sleep researcher Dr Marie-Pierre St-Onge advise people to focus first on behavioral changes rather than pills. Cognitive behavioral therapy for insomnia, or CBT-I, is considered the most effective treatment for sleep problems in both adults and children. It relies on structured habits and practical adjustments that continue to help long after the treatment period ends.