The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.

Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.

Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.

1. HIV is a Virus; AIDS is a Syndrome

HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.

AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.

2. Not Everyone with HIV Develops AIDS

A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.

Without treatment, however, HIV progresses through three stages:

- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.

- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.

- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.

3. HIV is Transmissible; AIDS is Not

Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.

AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.

4. Diagnosis Methods Differ

HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.

AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.

5. Treatment Goals Are Different

The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.

For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.

Role of Community Engagement in Combatting HIV/AIDS

While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."

Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.

The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.

Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.

Actress Amanda Peet has opened up about her breast cancer diagnosis, revealing a “weird” change in the skin that did not feel like the typical lump many people associate with breast cancer.

A breast lump is a well-known warning sign of breast cancer, but the disease can also cause changes in the breast’s skin, shape or texture. This makes it important to pay attention to changes that may not feel like a distinct lump.

What Did Amanda Peet Feel?

Peet, 54, recalled noticing something unusual while getting dressed.

“I was in my closet, I was probably putting something on and I felt a weird — it just didn’t feel like normal skin, but it wasn’t the frozen pea that everybody talks about,” she told Today.com.

Peet described the sensation as a change in how the skin felt rather than a clearly defined lump.

Other breast cancer warning signs can include changes in breast size or shape, skin dimpling, swelling, redness, nipple changes or unusual discharge. Skin that becomes pitted and resembles an orange peel, known as peau d’orange, can also be a warning sign.

Importantly, breast cancer can sometimes be present without an obvious lump.

Peet had been undergoing regular breast screening and follow-up because of her breast health history. She has said that an MRI did not show the cancer, but a subsequent ultrasound detected an abnormality. A biopsy later confirmed a tumor.

She was diagnosed with hormone-receptor-positive, HER2-negative invasive lobular carcinoma and underwent a lumpectomy followed by radiation.

What Is Invasive Lobular Carcinoma?

Invasive lobular carcinoma (ILC) is the second most common type of invasive breast cancer and accounts for about 10% of invasive breast cancers.

Unlike many breast cancers that form a distinct lump, ILC can grow in a more diffuse pattern. It may cause thickening, fullness or a subtle change in the breast rather than a clearly defined mass.

Because of the way ILC grows, it can sometimes be harder to detect on mammography. Additional imaging, including ultrasound or MRI, may be used depending on an individual's symptoms, breast density and clinical assessment.

Most invasive lobular cancers are hormone-receptor positive. Peet wrote that she had been seeing a breast surgeon every six months for checkups. Her cancer was diagnosed at Stage 1.

“I think about how lucky I was in so many ways,” she said.

Why Early Detection Matters

Breast cancer screening is designed to detect cancer before signs or symptoms become apparent. The goal is early detection, when treatment may be more effective.

The appropriate screening schedule depends on age, breast cancer risk, family history and other factors. In the US, the US Preventive Services Task Force recommends that women at average risk aged 40 to 74 have a mammogram every two years.

People with a higher risk of breast cancer may need a different screening approach or additional imaging. Discussing individual risk and screening options with a healthcare professional can help determine what is appropriate.

October Is Breast Cancer Awareness Month

October marks Breast Cancer Awareness Month, with this year’s theme, “Every story is unique, every journey matters,” highlighting that every breast cancer experience is different.

According to the World Health Organization (WHO), breast cancer is the most common cancer among women. About 80% of breast cancers occur in women with no specific risk factors other than sex and age.

In 2024:

• 2.4 million women were diagnosed with breast cancer worldwide.
• 694,000 women died from the disease.
• 8.2 million women were living with breast cancer at the end of the year.

After eliminating measles in 2000, the US is now seeing a sharp increase in cases, with 3,659 confirmed cases reported as of September 24, 2026. Pennsylvania has reported five measles-related deaths this year, the first such deaths in the state in 35 years.

The number has risen significantly from previous years. The US reported 2,289 cases in 2025, compared with 285 in 2024 and just 85 cases in 2000.

Measles can cause serious complications, including pneumonia and encephalitis, or brain swelling, and can be fatal.

Two doses of the measles, mumps and rubella (MMR) vaccine can prevent measles by up to 97%, although breakthrough infections can still occur.

Around 95% of reported cases have been among unvaccinated people, although breakthrough infections have also been reported among people who were fully vaccinated. However, measles is not expected to be as severe in people who are vaccinated.

“Their illness will be much more mild and less likely to cause serious illness than if they had not received two vaccines,” Dr. Pia Fenimore, chief and vice chair of pediatrics at Penn Medicine Lancaster General Health.

Yet according to experts some people can take a booster shot to stay safe.

Who May Need a Measles Booster?

The first measles vaccine was introduced in the US in 1963, but the formulation used between 1963 and 1967 was less effective than current versions.

Adults vaccinated during that period may need another dose if they have not received a later measles vaccine.

People born before 1957 are generally considered to have presumptive evidence of immunity because measles circulated widely before routine vaccination, and most people in this age group were naturally infected.

Some people may need individualized vaccination guidance rather than standard recommendations, including:

• People with uncertain vaccination status or no vaccination records
• People who received an inactivated measles vaccine between 1963 and 1967
• People with a weakened immune system
• Pregnant people

A measles vaccine booster may also be considered for children who received only one MMR dose, high-risk adults such as healthcare workers or international travelers, and people whose testing shows they lack immunity.

Can A Blood Test Check Measles Immunity?

In cases where people do not remember or have no records of two-dose measles vaccination, an Immunoglobulin G (IgG) antibody test can help assess whether they have antibodies against measles.

If testing shows sufficient measles IgG antibodies, the person is considered immune. If immunity is not established, vaccination may be recommended based on their individual circumstances.

Why Adults Also Need To Be Alert

Measles is often associated with children, but adults can also become infected.

“We often forget about adults getting measles ... 38% to 40% of cases this year of measles have been in adults. Adults become infected at the same, if not higher, rates than children themselves ... in 2025, just over half of the measles hospitalizations were actually ... adults,” Dr. Gavin Harris, an infectious diseases physician with Emory Healthcare in Georgia and the associate medical director of the Serious Communicable Diseases Unit.

What If You Were Exposed To Measles?

Measles is highly contagious and can spread through even limited exposure to the virus. With the virus outbreak, it is likely for people to get exposed to it.

The measles vaccine remains the absolute best way to prevent disease.

A shot within three days of exposure to the contagious virus can help prevent the disease. Intravenous immunoglobulin (IVIG) given within six days can also provide protection after exposure.

A 30-year-old law student with Type 1 diabetes was hospitalized with diabetic ketoacidosis (DKA) after allegedly being advised to stop insulin while following the “VRK Diet” promoted by social media personality Veeramachineni Ramakrishna, popularly known as VRK.

According to the complaint, the student had been living with Type 1 diabetes since 2018. He alleged that he came across VRK’s social media videos claiming that the diet could permanently cure conditions including Type 1 diabetes, cancer and kidney disease.

The student later visited the VRK Health Care Centre in Hyderabad in September 2025, where he alleged that he was orally advised to stop taking insulin. He said he paid around ₹26,000 for supplements and services at the center.

Two days later, he was admitted to a private hospital with DKA and severe dehydration, according to the complaint. He was later discharged.

Hyderabad police have booked Ramakrishna and another person in an alleged fake-doctor and fraud case.

Why Type 1 Diabetes Patients Must Never Stop Insulin

Also read: Gut Microbiome Linked To 3x Higher Type 1 Diabetes Risk In Children

More than 9 million people worldwide are estimated to be living with Type 1 diabetes, including about 1.8 million children and adolescents.

Type 1 diabetes occurs when the body cannot produce insulin. Insulin helps glucose move from the blood into cells, where it is used for energy. People with Type 1 diabetes therefore need insulin to control their blood glucose.

“Insulin is not optional in Type 1 diabetes,” Dr Sudhir Kumar, neurologist at Apollo Hospitals, Hyderabad, said in a post on X.

He advised people with Type 1 diabetes to never stop insulin on their own, including when they are unwell or unable to eat.

“Insulin doses may sometimes need adjustment, but this should be done with guidance from your diabetes team,” he said.

What Happens If Insulin Is Stopped?

The NHS UK explains that the human body needs insulin to break down glucose, i.e. sugar, to turn it into energy. People who have type 1 diabetes need insulin devices as their own body cannot produce it.

When the body does not have enough insulin, it cannot properly use glucose for energy. It starts breaking down fat instead, producing chemicals called ketones.

If ketones build up in the blood, they can cause diabetic ketoacidosis, a serious and potentially life-threatening complication.

DKA can develop when there is too little insulin, including when a person with Type 1 diabetes misses insulin doses.

Dr Kumar advised people with Type 1 diabetes to regularly monitor their blood glucose and check blood or urine ketones when indicated, particularly during illness or persistent high blood sugar.

Also read: H. pylori, HPV Among Five Infections Behind 1 In 8 Cancers Worldwide: Lancet

Warning Signs Of Diabetic Ketoacidosis

Dr Kumar said people with Type 1 diabetes should know the warning signs of DKA, including:

• Excessive thirst
• Frequent urination
• Nausea or vomiting
• Abdominal pain
• Dehydration
• Rapid or deep breathing
• Drowsiness or confusion

Anyone with symptoms suggestive of DKA should seek urgent medical care.

Can Diet Or Supplements Replace Insulin?

Type 1 diabetes is an incurable condition. Dr Kumar warned people to be extremely cautious about claims that Type 1 diabetes can be “cured” through supplements, diets, herbs or alternative treatments that allow insulin to be stopped.

“Check the qualifications and registration of anyone giving medical advice. Social-media popularity is NOT a substitute for medical training,” he said.

“One wrong piece of advice can have life-threatening consequences. For Type 1 diabetes, evidence-based medical care and uninterrupted access to insulin are essential,” he added.