World Aids Day
The global challenge of HIV/AIDS remains one of the most pressing public health issues today. According to the latest data from UNAIDS, around 38.4 million people worldwide are living with HIV/AIDS, underlining the need for not only medical intervention but also comprehensive awareness, education, and social change. Despite the significant strides made in treatment and prevention, the confusion surrounding the relationship between HIV and AIDS still persists.
Young people have become influential advocates in the fight against HIV/AIDS. Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities. These young activists utilize digital platforms and peer-to-peer education to dispel myths, promote safe practices, and foster supportive environments for those affected by HIV/AIDS.
Dr Gowri Kulkarni, an expert in Internal Medicine, explains that while the terms HIV and AIDS are often used interchangeably, they are distinctly different. "HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system, whereas AIDS (Acquired Immunodeficiency Syndrome) is a condition that occurs when HIV severely damages the immune system," she clarifies. To understand the implications of these differences, it's important to explore the fundamental distinctions between the two.
HIV is the virus responsible for attacking the body’s immune system, specifically targeting CD4 cells, which are crucial for the body’s defense against infections. As HIV progresses, it destroys these cells, weakening the immune system over time. If left untreated, this continuous damage can lead to AIDS.
AIDS, on the other hand, is a syndrome, not a virus. Dr Kulkarni further elaborates that AIDS is a collection of symptoms and illnesses that emerge when the immune system is severely compromised due to prolonged HIV infection. It represents the most advanced stage of HIV, and is characterized by very low CD4 counts or the onset of opportunistic infections like tuberculosis, pneumonia, or certain cancers.
A key distinction to remember is that not everyone with HIV will progress to AIDS. Thanks to advancements in medicine, particularly antiretroviral therapy (ART), individuals living with HIV can manage the virus and maintain a healthy immune system for many years, or even decades, without ever developing AIDS. ART works by suppressing the virus to undetectable levels, effectively preventing the damage HIV would otherwise cause to the immune system.
Without treatment, however, HIV progresses through three stages:
- Acute HIV Infection: This stage occurs shortly after transmission and may include symptoms like fever, fatigue, and swollen lymph nodes.
- Chronic HIV Infection: Often asymptomatic or mildly symptomatic, the virus continues to damage the immune system but at a slower rate.
- AIDS: This is the final stage, marked by severe immune damage and the presence of infections that take advantage of the compromised immune defenses.
Another key distinction between HIV and AIDS is the way in which they are transmitted. HIV is highly contagious and can be transmitted through the exchange of bodily fluids such as blood, semen, vaginal fluids, and breast milk. It is primarily spread through unprotected sexual contact, sharing needles, or from mother to child during childbirth or breastfeeding.
AIDS, however, is not transmissible. It is not a disease that can be passed from one person to another. Rather, AIDS is the result of untreated, advanced HIV infection and is a direct consequence of the virus’s damage to the immune system.
HIV and AIDS are diagnosed through different methods. HIV is diagnosed through blood tests or oral swabs that detect the presence of the virus or antibodies produced by the immune system in response to the virus. Early detection of HIV is crucial, as it allows for timely intervention and treatment, which can prevent the virus from progressing to AIDS.
AIDS, on the other hand, is diagnosed using more specific criteria. Dr Kulkarni notes that the diagnosis of AIDS is made when the individual’s CD4 cell count falls below 200 cells/mm³, or when opportunistic infections or certain cancers (such as Kaposi's sarcoma or lymphoma) are detected. Diagnosing AIDS involves a more thorough assessment of the individual’s immune function and overall health, as opposed to just the detection of HIV.
The treatment goals for HIV and AIDS differ significantly, although both involve antiretroviral therapy (ART). For HIV, the primary treatment goal is to suppress the virus to undetectable levels, thus maintaining a strong immune system and preventing further transmission of the virus. People living with HIV can often live long, healthy lives if they adhere to ART.
For individuals diagnosed with AIDS, the treatment plan becomes more complex. While ART remains an essential part of managing the virus, treatment for AIDS also focuses on addressing the opportunistic infections and secondary health complications associated with severe immune suppression. The goal of treatment for AIDS is not only to manage the HIV virus but also to improve the quality of life and extend survival by treating these secondary health issues.
While the medical community has made great strides in managing HIV, the battle to curb its transmission is also a social and cultural issue. Dr Daman Ahuja, a public health expert, highlights that HIV/AIDS awareness and education are vital to reducing transmission rates and supporting those affected by the virus. "Young people, especially, have become key advocates in the fight against HIV/AIDS," says Dr Ahuja. "Research from UNICEF shows that youth-led initiatives can lower HIV transmission rates by as much as 45% in targeted communities."
Additionally, grassroots activism plays a significant role in raising awareness and addressing stigma. As the World Health Organization reports, community-based interventions have been proven to increase HIV testing rates and improve treatment adherence, which are crucial in the fight against the pandemic.
The ultimate goal of organizations like UNAIDS is to eliminate the HIV/AIDS pandemic by 2030. Achieving this requires global collaboration, from medical treatment advancements to public health strategies, education, and advocacy. Dr Kulkarni’s insight underscores the importance of early detection, treatment adherence, and community support in the fight against HIV/AIDS.
Dr Gowri Kulkarni is Head of Medical Operations at MediBuddy and Dr Daman Ahuja, a public health expert and has been associated with Red Ribbon Express Project of NACO between 2007-12.
Credits: Canva
A little-known virus is spreading steadily across different parts of the world, prompting growing concern among health experts. Often described as “untreatable” because there is no targeted antiviral medicine available, adenovirus is drawing attention due to how tough it is and how quickly it can pass from person to person.
Eric Sachinwalla, medical director of infection prevention and control at Jefferson Health, has cautioned that while most healthy individuals develop only mild illness, people in high-risk groups may face more serious health problems. This raises an important question: just how contagious is this mystery illness that is spreading?
Yes, adenovirus is highly contagious and spreads with ease in several ways. It can pass through respiratory droplets released during coughing or sneezing, close physical contact such as hugging or shaking hands, and contact with contaminated surfaces like toys and towels.
It can also spread through fecal matter, particularly during diaper changes, and in some cases through water. According to the CDC, the virus spreads quickly in crowded settings such as schools and daycare centres and can survive for long periods on surfaces, making good hygiene especially important for young children and people with weakened immune systems.
Adenoviruses can infect people of all age groups, but they are most commonly seen in children under the age of five. In babies and young children, the virus often spreads in daycare environments where close contact is common. Children are also more likely to put shared objects in their mouths and may not wash their hands as regularly.
Among adults, adenoviruses tend to spread in crowded living conditions. People staying in dormitories or military housing may have a higher risk of infection. The virus is also known to circulate in hospitals and nursing homes, as per CDC.
Those with weakened immune systems are more likely to become seriously ill from an adenovirus infection. This includes people who have undergone organ or stem cell transplants, as well as those living with cancer or HIV/AIDS. Individuals with existing heart or lung conditions may also face a higher risk of severe illness.
The symptoms of an adenovirus infection depend on the part of the body affected. Most commonly, the virus targets the respiratory system. When it infects the airways, it can cause symptoms similar to a cold or the flu. These may include:
Adenoviruses can also infect the digestive system. When this happens, diarrhea may occur, along with gastroenteritis. Gastroenteritis is inflammation of the stomach or intestines and can lead to stomach pain, diarrhea, nausea, and vomiting.
In rarer cases, adenoviruses can affect the bladder or the nervous system. Infection of the bladder may result in urinary tract infections. When the nervous system is involved, it can lead to serious conditions affecting the brain, including encephalitis and meningitis.
Credits: Canva
Influenza, commonly called the flu, is a respiratory infection caused by the influenza virus. It is contagious, which means it passes easily from one person to another. Although influenza viruses can circulate throughout the year, infections are seen more often during the fall and winter months. This time is known as the flu season. As flu cases are rising across many parts of the US and UK, here are a few key points to understand, from the incubation period to how easily the virus spreads.
The flu is an infection caused by the influenza virus. It usually leads to symptoms such as body and head aches, sore throat, fever, and breathing-related discomfort, which can sometimes become serious. Flu cases tend to peak during the winter months, when large numbers of people may fall ill at the same time, a situation described as an epidemic, according to the Cleveland Clinic.
The average incubation period of the flu is around 2 days, though it can vary from 1 to 4 days. In simple terms, this means most people begin to notice flu symptoms a few days after the virus enters the body.
After catching the flu virus, a person can start passing it on to others about 1 dayTrusted Source before symptoms appear. Keep in mind that the usual incubation period is about 2 days. So, if someone is exposed to the virus on a Saturday morning, they may already be able to spread it by Sunday evening. By Monday afternoon, flu symptoms are likely to show up. These symptoms can be mild or severe.
Some people may not develop symptoms at all, but they can still spread the virus. The flu is usually most contagious during the first 3 days of illness. After symptoms begin, a person may continue to infect others for another 5 to 7 days. Children, older adults, and people with weaker immune systems may remain contagious for a longer time.
Unlike the common cold, which tends to develop slowly, flu symptoms often appear suddenly.
Common symptoms include:
Most people start to feel better within a few days to two weeks. However, some individuals may need antiviral medication, particularly those at higher risk of serious complications.
The flu mainly spreads through tiny respiratory droplets released when an infected person coughs or sneezes. In crowded places, these particles can be inhaled by others, leading to infection. The virus can also spread by touching objects or surfaces that carry the virus, such as door handles or shared personal items. Outside the body, the virus can survive on surfaces for up to one day.
If someone touches a contaminated surface and then touches their eyes, nose, or mouth, the flu virus can enter the body and cause infection.
Credits: Canva
People who are prescribed blood thinners, also known as anticoagulants, could unknowingly weaken the effect of their medication by eating a widely consumed and otherwise healthy vegetable, a doctor has warned.
Anticoagulants are routinely given to reduce the risk of blood clots and are often prescribed to those who face a higher chance of such complications. This group also includes people at increased risk of heart attacks or strokes. These medicines, which include rivaroxaban, apixaban and warfarin, work by interrupting the clotting process and play a key role in preventing serious conditions such as strokes, heart attacks, pulmonary embolism and deep vein thrombosis.
While anticoagulants are effective and often lifesaving, patients are being advised that a familiar garden vegetable could interfere with how well these drugs work. The warning comes from Dr Chris Steele, who appeared on ITV’s This Morning to explain how certain foods can interact negatively with different medications.
As part of his advice, he said, as per Express, “Leafy greens are high in vitamin K, which helps blood to clot. Warfarin works by blocking vitamin K production, so if you suddenly increase how many greens you eat, it can affect how the medicine works.”
He added: “Other foods that contain a lot of vitamin K include green vegetables, egg yolks, chickpeas and lentils. These foods don’t need to be removed from the diet, but it is important to keep your intake steady and consistent. You should also avoid drinking large amounts of cranberry juice or using cranberry products while on anticoagulants, as they can alter the effect of warfarin. Garlic and ginger should be limited too, as they can raise the risk of bleeding.”
Dr Chris also highlighted that many other medicines can react in unexpected ways when taken alongside certain foods and drinks. For example, he noted that some antibiotics, including ciprofloxacin, can react poorly with milk.
He explained: “Calcium can reduce how well some antibiotics work, so these medicines should not be taken at the same time as foods high in calcium, such as milk, yoghurt or cheese. Calcium supplements should also be avoided for a few hours before and after taking these antibiotics.
“You should not drink milk when taking certain antibiotics, including tetracycline and ciprofloxacin, which are quinolone antibiotics, or some osteoporosis drugs like alendronate, also known as Fosamax.”
He further advised avoiding the following combinations with specific medicines:
Dr Chris stressed: “Always speak to your doctor about any precautions you should follow when starting a new medication. You may need to avoid certain foods, make changes to your lifestyle, or take other steps to prevent unwanted side effects.”
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