As you grow old, your health starts to deteriorate. Everything, whether it is your mental health or your physical health, starts to slow down. However, with age, your mental health gets overshadowed by your physical health.

Signs You Should Note

If you note these signs in your ageing parents or grandparents, take note of it. Try to get involved with them. It is also important to ensure that they have a separate social circle apart from the family. This way, they can have friends who they can also relate to.

With age, suggests Sinha, you are more prone to be depressed, and anxious. “Mental health conditions like schizophrenia or bipolar disorders are not something that happens when you grow older. You may have been living with these for the last 40 years, but the management differs, she suggests.

As you grow old, your symptoms start to overlap with other mental health conditions. For the proper treatment professionals use differential diagnosis, suggests Sinha. “The lines become blurred and to differentiate the symptoms from one mental health condition to another becomes difficult,” she says.

Preventive Measures

There are also food habits like eating leafy vegetables, nuts, fish, virgin coconut and beans that help with brain functions.

Sinha suggests that keeping a social circle and continuing your hobbies can help your mind stay healthy. “Men especially face this issue, after they retire, they feel like they are at the loss of authority, and they start to lose control. It is thus important to keep doing things and learning a new skill to keep your brain active. While for women, since they continue taking care of the house, their brain stays active,” she says.

Cognitive stimulation is the key, especially to managing dementia, she notes.

“Just with weight training, you push your body and after a while, it becomes your muscle memory. Same with the brain. However, one should not get into solving too many puzzles, or trivia after being diagnosed with dementia. Because that would mean you are making your already injured brain exercise which might lead to agitation,” she recommends.

How to support?

“The most important part is for the caregiver to understand what is happening and come to terms with the conditions. Because the elderly with cognitive conditions are not able to understand, they cannot be told or instructed to do anything. Thus, the responsibility is solely on the caregiver,” points out Sinha.

So, what can be done?

Awareness

Reach out to therapists and counsellors to know the ways to create such a healthy environment.

Be Patient

She suggests adopting the same approach that you do with kids and with your pets. This is when you focus on gestures, body language and mood over language. Due to cognitive disorders, parents experience a loss of language and the only way to communicate and to understand what they are communicating is through these means.

Be Empathetic

Create a healthy environment by agreeing with them and listening to their stories. The responsibility of creating a safe environment is totally with you.

There might be times when your parents may do socially unacceptable or non-compliance behaviour. But it is important to understand the triggers and ensure that the triggers do not occur anymore.

Help Them Stay Fit

Vitiligo is an autoimmune condition that causes pigment loss in patches of skin. It is highly treatable and does not spread from person to person. However, stress, poor sleep, diet, and overall immune health may influence how active the condition becomes, experts said today on World Vitiligo Day.

Awareness around vitiligo remains low and is often clouded by misconceptions. Observed annually on June 25, World Vitiligo Day aims to raise awareness and challenge the stigma associated with the condition.

HealthandMe spoke to experts to understand the disease and the factors that may affect it.

Dr. Rashmi Ranjan, Consultant – Dermatology, Yatharth Super Speciality Hospital, Noida, said the biggest misconception is that vitiligo is contagious.

"It cannot spread from one person to another through touch, sharing food, or close contact."

Dr. Rashmi told HealthandMe that many people also incorrectly believe vitiligo is caused by poor hygiene or specific foods, claims that are not supported by scientific evidence.

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What Is Vitiligo?

Vitiligo occurs when the body's immune system attacks melanocytes, the cells responsible for producing skin pigment. While the condition is not life-threatening, it can have a significant emotional and psychological impact.

“As a chronic autoimmune disorder, vitiligo develops when the body's immune system mistakenly attacks melanocytes—the cells responsible for producing skin pigment. The result is the appearance of white patches that can develop anywhere on the body and may gradually increase in size or number over time,” Dr Hetanshu Parekh, Consultant Plastic Reconstructive & Cosmetic Surgeon, Bhailal Amin General Hospital, told HealthandMe.

The Emotional Impact of Vitiligo

The theme of World Vitiligo Day 2026 is "From Stigma to Strength".

According to Dr. Rashmi, visible skin changes often attract unwanted attention, questions and social judgment. Some people may avoid social gatherings or experience challenges in relationships and employment because of persistent misconceptions.

Children may face bullying, while adults can struggle with anxiety and low self-esteem. Emotional support from family, friends and healthcare professionals is therefore crucial.

A recent study also highlighted a strong link between vitiligo and mental health in India. Nearly 89% of patients reported moderate to severe depression, while close to 60% said they covered their patches, underscoring the continuing impact of stigma.

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Vitiligo and the Role of Lifestyle Factors

Dr Hetanshu said vitiligo is often viewed as a skin condition alone, but the disease is far more complex. He explained that

Stress

• Stress can disrupt immune balance and increase inflammation, potentially worsening vitiligo.
• New or expanding patches are often observed after major life events such as exams, work pressure, illness, financial difficulties or bereavement.

Sleep

• Quality sleep is essential for immune regulation and overall health.
• Chronic sleep deprivation, irregular sleep schedules or less than six hours of sleep may worsen autoimmune conditions, including vitiligo.

Diet

• There is no specific "vitiligo diet" and no food can cure the condition.
• Deficiencies in Vitamin B12, Vitamin D, folate and copper may affect immune and skin health.
• Experts recommend an anti-inflammatory diet rich in fruits, vegetables, whole grains, nuts, seeds and omega-3 fatty acids.
• Smoking and excessive alcohol consumption should be avoided.

Skin Protection

• Repeated friction, cuts, burns and excessive sun exposure may trigger vitiligo patches (Koebner phenomenon).
• Use sunscreen regularly, wear protective clothing and avoid unnecessary skin trauma from tight straps, jewellery or repetitive rubbing.

Is Vitiligo Treatable?

Advances in targeted topical medications, phototherapy and immune-modulating therapies have expanded treatment options and enabled more personalized care, said Dr. Rashmi told HealthandMe.

Dr Hetanshu stressed that lifestyle measures should complement, not replace, medical treatment. Treatment measures include:

• For small, stable patches, doctors commonly prescribe corticosteroid creams and tacrolimus ointment.
• More extensive or rapidly spreading vitiligo may require narrowband UVB phototherapy, excimer laser therapy, oral corticosteroids or newer JAK inhibitors such as tofacitinib and ritlecitinib.
• Patients with stable disease for six to twelve months may be candidates for surgical procedures such as skin grafting and melanocyte transplantation.
• Medical tattooing and camouflage techniques can help in difficult-to-treat areas.

Blood cancers are among the most challenging, but advances in treatments, such as targeted therapies, advanced transplantation techniques, and increasingly customized approaches, are offering a new ray of hope for patients. Among these innovations, Chimeric Antigen Receptor T-cell therapy, commonly known as CAR-T cell therapy, represents one of the most important breakthroughs in modern cancer care in recent times.

Unlike conventional treatments that directly target cancer cells, CAR-T cell therapy harnesses the patient's immune system to identify and attack cancer. It is a powerful example of how medicine is moving towards personalized treatment strategies that are designed around an individual's disease biology.

How CAR-T Cell Therapy Works

To understand CAR-T therapy, it is important to understand the role of T-cells. These are specialized immune cells responsible for recognizing and eliminating abnormal cells in the body. In some blood cancers, cancer cells develop mechanisms that allow them to evade immune surveillance. CAR-T therapy addresses this challenge by genetically modifying a patient's T-cells in a laboratory to recognize specific proteins present on cancer cells.

The process begins with the collection of T-cells from the patient's blood through leukapheresis. These cells are then engineered to express specialized receptors, called chimeric antigen receptors (CARs), which enable them to recognize cancer cells more effectively. Once modified and multiplied, the cells are infused back into the patient's bloodstream, where they seek out and destroy cancer cells.

Potential of CAR-T

Currently, CAR-T cell therapy has shown encouraging results in several blood cancers, including certain forms of acute lymphoblastic leukemia, diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma, follicular lymphoma, and multiple myeloma. For some patients whose disease has relapsed after multiple lines of treatment or failed to respond to conventional therapies, CAR-T therapy has offered a valuable new treatment option.

One of the most promising aspects of CAR-T therapy is its potential for durable responses. In selected patients, the engineered immune cells can continue to remain active within the body, providing ongoing surveillance against cancer recurrence. While every patient may not experience the same outcome, the ability to achieve long-lasting remission in heavily pre-treated cancers has generated significant optimism within the oncology community.

CAR-T therapy: The Challenges And Side Effects

All that being said, CAR-T therapy is a highly specialized treatment that requires careful patient selection and close monitoring. Some patients may also experience side effects such as cytokine release syndrome (CRS), neurological complications, or temporary suppression of normal blood cell production. Fortunately, advances in supportive care and growing clinical experience have substantially improved the management of these complications.

The Future of Blood Cancer Care

Researchers across the world are working on next-generation CAR-T platforms designed to improve effectiveness, reduce toxicity and expand treatment eligibility. Investigational approaches include "off-the-shelf" CAR-T products derived from healthy donors, dual-target CAR-T cells capable of recognizing multiple cancer markers, and therapies aimed at overcoming treatment resistance.

Scientists have also been exploring the potential of CAR-T therapy in other blood cancers and even selected solid tumors. While significant challenges remain, ongoing research continues to push the boundaries of what immune-based therapies can achieve. As research advances and access continues to improve, CAR-T cell therapy is expected to play a very important role in the future of blood cancer care. For patients, families, and clinicians alike, it represents a powerful reminder that innovation continues to redefine what is possible in the fight against cancer.

(By Dr. Dinesh Bhurani, Director – Hemato-Oncology & Bone Marrow Transplant, Rajiv Gandhi Cancer Institute & Research Centre (RGCIRC))

Keeping your cholesterol levels in a healthy range is one of the best things you can do for your heart. High cholesterol is a major risk factor for heart disease, but the good news is that what you eat can make a significant difference. While some people may need medication, research shows that certain foods can naturally help lower LDL cholesterol and support overall cardiovascular health.

One of the easiest places to start is with oats. Oats are packed with a soluble fiber called beta-glucan, which helps reduce the amount of cholesterol absorbed into your bloodstream. A review published in Nutrients found that regularly eating oat beta-glucan can lead to meaningful reductions in LDL cholesterol, especially when combined with an overall heart-healthy diet.

Legumes such as beans, lentils, and chickpeas are another powerful addition to your plate. They're rich in fiber and plant-based protein, making them an excellent alternative to processed meats and other foods high in saturated fat. Research has consistently linked regular legume consumption with lower LDL cholesterol levels and better heart health.

Nuts also deserve a place in a cholesterol-friendly diet. Almonds, walnuts, and other tree nuts provide healthy unsaturated fats, fiber, and antioxidants. According to studies published in the American Journal of Clinical Nutrition, moderate nut consumption can help improve cholesterol levels and support cardiovascular health.

Fatty fish like salmon, sardines, and mackerel are well known for their heart-protective benefits. These fish are rich in omega-3 fatty acids, which can help lower triglycerides and support healthy blood vessels. The American Heart Association recommends eating fatty fish at least twice a week as part of a balanced diet.

Fruits and vegetables remain some of the most important foods for maintaining healthy cholesterol levels. Apples, berries, oranges, leafy greens, and broccoli provide fiber, vitamins, antioxidants, and plant compounds that help protect the heart. Numerous studies have shown that diets rich in fruits and vegetables are associated with a lower risk of cardiovascular disease.

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Avocados are another heart-smart choice. They contain monounsaturated fats and fiber, both of which can help improve cholesterol levels when used in place of foods high in saturated fat. A clinical study published in the Journal of the American Heart Association found that people who ate one avocado daily experienced greater reductions in LDL cholesterol than those following similar diets without avocado.

The bottom line is that controlling cholesterol doesn't require a drastic diet overhaul. Small, consistent changes—such as eating more whole grains, legumes, nuts, fruits, vegetables, fatty fish, and healthy fats—can have a lasting impact on heart health. Combined with regular exercise and other healthy lifestyle habits, these foods can help keep your cholesterol in check and support long-term well-being.