
Walking (Credit: Canva)
Walking is more than just a way to move from point A to point B—it may be a simple yet powerful way to boost your mental health. While it is constantly known to impact your physical well-being, research has found that it can also help you tackle depression. According to the study, adults walking 5,000 or more steps daily experienced fewer depression symptoms compared to those who walked less. Mental Health benefits increased with more steps. For instance, research participants, who walked over for at least 7,500 steps every day saw a 42% reduction in depression symptoms.
Interestingly, even a modest boost in daily steps made a difference. Adding just 1,000 extra steps daily was linked to a lower risk of depression. Another analysis from the same study highlighted that people who hit 7,000 steps or more each day were less likely to develop depression than those who walked less. Experts have said that walking may reliably reduce depression by measurable amounts while also potentially lowering the risk of developing depression.
For their research, experts reviewed data from 33 studies involving over 96,000 adults to explore the link between walking and reduced depression symptoms. The studies used wearable devices like pedometers and smartphones to measure participants' step counts, typically over a week. The meta-analysis found that walking not only reduced depression symptoms but also served as a practical, low-pressure alternative to structured exercise, especially for those who might find more intensive workouts intimidating.
However, the researchers acknowledged some limitations. People who walked more might already feel better, and the study didn’t explore other factors, such as the potential benefits of walking in nature or with others, which could further improve mood.
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Sleep is one of the most important factors for overall health and well-being, influencing both physical and mental health. Yet, how much sleep a person actually needs remains a common topic of debate.
Dr Sudhir Kumar, a neurologist at Apollo Hospitals, addressed several misconceptions and shared evidence-based insights about sleep that everyone should know.
In a detailed post on social media platform X, Dr Sudhir said that most adults need 7–9 hours of sleep per night.
While some may function well with slightly less or more sleep, he noted that "regularly sleeping less than six hours or more than 9–10 hours is associated with adverse health outcomes."
While sleep duration is important, sleep consistency is equally important.
"Going to bed and waking up at roughly the same time every day helps regulate your circadian rhythm," he said.
Irregular sleep schedules, on the other hand, are associated with poorer metabolic health, mood disturbances, and daytime sleepiness.
Dr Sudhir said that most modern adults follow a monophasic pattern, with one main sleep period at night.
However, "a biphasic pattern (night sleep plus a short afternoon nap) can also be healthy if total sleep duration is adequate and the nap does not interfere with nighttime sleep."
Not necessarily, said Dr Sudhir, popularly known as Hyderabaddoc on X, adding that many healthy adults do perfectly well without naps.
However, naps may be particularly useful for:
• Shift workers
• People with sleep debt
• Older adults with increased daytime sleepiness
• Those performing safety-critical tasks requiring sustained alertness
Further, he said that a 10–30-minute nap, also known as a power nap, is usually best, and may help:
• Improve alertness
• Improve concentration
• Reduce fatigue
• Enhance performance
However, naps lasting more than an hour may cause "sleep inertia" (grogginess) and disrupt nighttime sleep in some individuals.
"Night shift work is not biologically normal," Dr Sudhir said.
Humans are programmed to be awake during the day and asleep at night. Long-term night shift work has been associated with increased risks of:
• Obesity
• Type 2 diabetes
• Cardiovascular disease
• Mood disorders
• Workplace accidents
Dr Sudhir also addressed the common belief that people can make up for lost sleep during weekends.
While "partial recovery is possible," he said weekend catch-up sleep does not fully reverse the effects of chronic sleep deprivation.
Large shifts in sleep timing during weekends, often referred to as "social jet lag," can disrupt circadian rhythms.
He advised keeping wake-up and bedtime within about one to two hours of the weekday schedule.
He also warned against relying on multiple alarms every morning, which according to him "suggests insufficient sleep, poor sleep quality, and circadian misalignment."
Dr Sudhir said regularly sleeping more than 9–10 hours may be associated with higher risks of cardiovascular disease, depression, frailty, and mortality.
At the same time, the neurologist noted that "even one night of inadequate sleep can impair performance".
Short-term sleep deprivation can lead to:
• Reduced attention
• Slower reaction time
• Poor decision-making
• Mood changes
• Increased accident risk
Chronic insufficient sleep is associated with:
• Hypertension
• Type 2 diabetes
• Obesity
• Cardiovascular disease
• Depression and anxiety
• Cognitive decline
• Reduced quality of life
"Sleep is a fundamental biological requirement, just like nutrition and exercise," Dr Sudhir said.
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GLP-1 receptor agonists (GLP-1 RAs), including semaglutide widely used to improve diabetes control and promote weight loss, may also reduce the risk of colorectal cancer, according to a new study.
The study found that the effect was particularly notable among people with inflammatory bowel disease (IBD), as well as those with both IBD and type 2 diabetes. Both conditions are associated with a higher risk of colorectal cancer due to chronic inflammation and metabolic changes that may promote tumor development.
"GLP-1 RA use was associated with a significantly reduced incidence of colorectal cancer in all patients with IBD, as well as the subpopulation with both IBD and type 2 diabetes," said lead author Sarina Ailawadi of Case Western Reserve University, US.
"Given the elevated colorectal cancer risk in IBD, these findings suggest a potential protective effect of GLP-1 RA use in this high-risk population. Prospective studies will be important to further analyze and confirm this potential benefit," she added.
The findings will be presented at the 2026 American Society of Clinical Oncology (ASCO) Breakthrough meeting, scheduled for June 25–27 in Singapore.
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This retrospective cohort study analyzed data from 69,221 people in the US, including GLP-1 RA users and non-users.
Researchers also identified 209,649 people with both IBD and type 2 diabetes, including 38,567 who had taken a GLP-1 RA.
After matching users and non-users for various characteristics, data from 37,740 patients were analyzed. The GLP-1 RA group included people taking semaglutide, dulaglutide, tirzepatide, exenatide, liraglutide, or lixisenatide.
The researchers compared the five-year incidence of colorectal cancer between GLP-1 RA users and non-users.
Among people with IBD, the five-year incidence of colorectal cancer was 0.2% in GLP-1 RA users compared with 0.42% in non-users. The odds ratio was 0.49, indicating a 51% lower likelihood of developing colorectal cancer among GLP-1 RA users.
Among patients with both IBD and type 2 diabetes, the five-year incidence of colorectal cancer was 0.31% in GLP-1 RA users and 0.57% in non-users. The odds ratio was 0.54, suggesting a 46% lower likelihood of developing colorectal cancer.
The researchers noted that prospective studies are needed to confirm the potential protective effect of GLP-1 RAs on colorectal cancer risk.
Inflammatory bowel disease is associated with a higher risk of colorectal cancer, likely because of chronic inflammation in the intestines. People with IBD are estimated to be six times more likely to develop colorectal cancer than those without the condition.
Type 2 diabetes, the most common form of diabetes, also increases colorectal cancer risk and is becoming more common among people with IBD. Scientists believe that individuals with both conditions may face an especially high risk because of the combined effects of chronic inflammation and metabolic dysfunction.
GLP-1 receptor agonists are a class of drugs that help lower blood sugar levels and promote weight loss. Originally developed to treat type 2 diabetes, many are now widely used for weight management.
These medications mimic the action of the GLP-1 hormone by stimulating insulin release, slowing digestion, and increasing feelings of fullness.
Beyond blood sugar control and weight loss, GLP-1 RAs have been linked to several health benefits, including lower blood pressure and reduced cardiovascular risk. Previous studies have also suggested that they may lower the risk of colorectal cancer and other obesity-related cancers.
However, their specific impact on colorectal cancer risk among people with IBD has remained unclear until now.
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A new study involving more than 13,000 parents suggests that parents who have sons may experience faster cognitive decline in later life compared to parents who only have daughters. While the findings may sound surprising, researchers stress that the results are linked to long-term caregiving and social support—not biology.
The research, published in the Journal of Psychiatric Research, explored how family composition might affect cognitive health as people grow older.
Researchers from Columbia University and Charles University analyzed data from 13,222 adults aged 50 and above who participated in the US Health and Retirement Study.
The team discovered several important patterns:
Parents with at least one son showed a faster rate of cognitive decline than parents who had only daughters.
The association was observed in both mothers and fathers, suggesting the effect is driven by social and caregiving factors rather than biological differences.
Parents with multiple sons experienced an even steeper decline in cognitive function over time compared to parents whose children were all daughters.
The researchers concluded that having sons was associated with a faster decline in memory and thinking abilities during older adulthood.
The researchers believe the explanation lies in family dynamics rather than genetics.
Previous studies have consistently shown that daughters are more likely to provide emotional support, regular communication, and hands-on caregiving as their parents age. This ongoing engagement may help keep parents mentally active and socially connected—two factors that are strongly associated with healthier brain aging.
Experts often refer to this as the "daughter effect." Strong emotional bonds and frequent social interactions are known to protect cognitive function and may reduce the risk of age-related mental decline.
Participants' cognitive abilities were evaluated every two years using several standard mental performance tests, including:
These assessments allowed researchers to track changes in memory, attention, and problem-solving skills over several years.
Even after adjusting for factors such as age, education, health status, and socioeconomic background, the relationship between having sons and faster cognitive decline remained significant.
Previous Research Supports Similar Findings:
The study also builds on earlier research that linked having more sons with poorer long-term maternal health outcomes, including an increased risk of dementia.
By examining both mothers and fathers, the new research suggests the relationship extends beyond pregnancy-related biological factors and is more likely connected to differences in caregiving and emotional support provided by adult children.
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The findings should not be interpreted as a reason to worry about having sons. Instead, they highlight the importance of maintaining strong family relationships, staying socially active, and ensuring older adults receive emotional and practical support regardless of their children's gender.
Researchers say that healthy aging depends on many interconnected factors, and supportive relationships can play an important role in preserving cognitive function over time.
The study suggests that parents with sons may experience faster cognitive decline than parents with only daughters, with the effect becoming stronger as the number of sons increases. However, experts caution that family composition is just one small piece of the puzzle. Healthy lifestyle habits, social connections, education, and quality caregiving remain the most important factors for maintaining brain health throughout aging.
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