We often see celebrities go through weight loss transformations, with side-by-side comparisons of the before and after weight loss. But people often do not feel inspired or drawn to their stories as we all know that they have access to great personal trainers, high-end food products as well as better access to healthcare. But one story that was highlighted by Men’s Health in their ‘First Steps’ series can inspire many with the story of Simon Lafontant, who lost 150 pounds and went on to become a body builder.

Simon Lafontant, a 32-year-old from Calgary, had to deal with some serious health problems for a long time. These included low testosterone and Crohn's disease, which made his life difficult. But Simon decided he wanted to make a change. He got medical help for his low testosterone and then set a big goal for himself: to compete in a bodybuilding competition. He used social media to keep himself on track, and he ended up losing over 150 pounds and even winning the competition! His story is about how he went from struggling with his health to becoming a bodybuilding champion.

How A Disease Can Become A Turning Point

Simon talks about how he used to have bad habits and wasn't living a healthy lifestyle. This led to him feeling down, gaining weight, and losing motivation. Things got really serious in 2020 when his Crohn's disease caused him to be in the hospital for seven whole months. According to Mayo Clinic Crohn’s disease is a type of inflammatory bowel disease that is inflammation in your digestive tract which can be very painful and can cause people to need long term remission and time to heal the inflammation. Simon spoke about how he realized his poor lifestyle choices and being obese had made his symptoms worse!

While you may not wish to become a bodybuilder, there are many other aspects you can take away from the Simon’s story! Another trip to the doctors revealed that he had very low testosterone levels, which explained his lack of energy. This was a major turning point for him, as he finally understood some of the reasons behind his struggles.

What Role Does Testosterone Play?

One thing that made a huge difference in Simon’s weight loss journey was getting the TRT treatment for his low testosterone which had an almost immediate effect on him. He felt good, started enjoying things again, like going outside and working out. He also remembered how much he loved powerlifting and Strongman competitions, so this helped him get on to his path to bodybuilding and weight training!

Low testosterone affects both men and women, but in different ways. In women, it can cause low sex drive, tiredness, muscle weakness, trouble getting pregnant, irregular periods, vaginal dryness, mood changes like depression or anxiety, hair thinning, dry skin, and sleep problems. In men, low testosterone can lead to reduced sex drive, erectile dysfunction, hair loss, smaller testicles, hot flashes, and infertility. Other symptoms in men include feeling down, trouble concentrating or remembering things, and increased body fat. If you're experiencing any of these symptoms, it's a good idea to talk to a doctor.

A majority of women may experience infections during the crucial phase of pregnancy. Some infections during pregnancy may also not show clear symptoms. However, timely awareness and prevention can protect both the mother and the baby.

Pregnancy is a special and sensitive phase in a woman’s life. While most women focus on nutrition and regular check-ups, infections during pregnancy can often be neglected.

Some infections may cause only mild symptoms in the mother but can seriously affect the unborn baby if not detected early. Hence, regular screening, good hygiene, and timely medical care are crucial to prevent most pregnancy-related infections and ensure a safe and healthy pregnancy.

Common Infections During Pregnancy

• Urinary Tract Infections (UTIs)

• Vaginal infections

• Respiratory infections

• TORCH infections

• Hepatitis B and C can be passed from mother to baby during childbirth if not properly managed.

Tips To Follow To Prevent Infections During Pregnancy

• Pregnant women should go for regular antenatal check-ups, maintain good personal hygiene, and not use any chemical-laden products.
• Stay hydrated and drink enough water, eat home-cooked food, avoid raw or undercooked items, wash your hands frequently, and get vaccinated as recommended by the doctor.
• Take a flu shot on a priority basis. Avoid contact with rodents and pets.
• Make sure to consult the expert in case of symptoms such as fever, pain, or unusual discharge for prompt intervention.
• Get tested for sexually transmitted diseases (STDs) such as HPV, chlamydia, gonorrhea, herpes, syphilis, and trichomoniasis.
• Early detection and treatment will be beneficial in safeguarding both mother and baby and ensuring a healthy pregnancy.

A severe influenza A virus, commonly known as seasonal flu, may not only leave you coughing and feeling feverish, but also silently damage your heart, increasing the risk of heart attacks, according to a study.

A team of researchers from the Icahn School of Medicine at Mount Sinai, New York, US, unraveled that the influenza A virus directly damages the heart by hijacking immune cells. This leads to long-lasting cardiac dysfunction even after the lung infection is cleared.

The study, published in February 2026 in the journal Immunity, focused on an immune cell, known as pro-dendritic cell 3.

The researchers revealed that the pro-dendritic cell 3 acts as the ‘Trojan horse’ of the immune system during flu infection and carries the virus to the heart from the lungs.

Once in the heart, it produces large amounts of type 1 interferon and triggers the death of cardiomyocytes, impairing cardiac output.

Importantly, the findings showed that an annual flu vaccine can prevent damage to the heart.

“We have known for years that the frequency of heart attacks increases during flu season, yet outside of clinical intuition, scant evidence exists of the underlying mechanisms of that phenomenon,” said senior author Filip Swirski, Director of the Cardiovascular Research Institute at the Icahn.

“These findings offer great promise for the development of new therapies, which are desperately needed since there are currently no viable clinical options to prevent cardiac damage,” Swirski added.

What The Study Found

The team studied autopsies of 35 hospitalized patients who died of influenza. Of these, more than 85 percent had at least one significant cardiovascular comorbidity, such as hypertension. A majority of them also had multiple comorbidities, including atherosclerosis and cardiac fibrosis, underscoring cardiovascular disease as a major driver of influenza mortality.

The study also provided evidence that a cutting-edge modified mRNA treatment that dampens an interferon signaling pathway in the heart can significantly mitigate cardiac damage following viral infection while preserving the protective antiviral response of the immune system.

“The hopeful news for patients is that by injecting a novel mod-RNA therapeutic that modulates the IFN-1 signaling pathway, we reduced levels of cardiac damage, as evidenced by lower troponin, and improved cardiac function, as measured by higher left ventricular ejection fraction,” explained Jeffrey Downey, a member of Dr. Swirski’s laboratory who served as lead author.

Influenza A Virus And The Heart

Global statistics show that influenza A viruses cause an estimated 1 billion infections each year. This ranges from seasonal flu outbreaks locally to pandemics globally.

While most infections are mild and self-resolving, in some cases, they can become severe or even fatal. When the virus travels to the heart, it triggers the death of cardiomyocytes -- specialized muscle cells that are responsible for the rhythmic contraction and relaxation of the heart.

Ramzan, the holiest month in Islam, marked by dawn-to-dusk fasting, poses health risks for people with diabetes. Health experts urge patients to consult their doctors before observing the fast.

Ramzan is a period of intense spiritual reflection, self-discipline, and devotion for Muslims worldwide. During the month-long fasting period, the believers refrain from eating and even drinking (including water), from dawn to sunset.

The faithful eat a modest meal (sehri) before the first light of dawn to provide energy for the day. The fast is broken at sunset, traditionally starting with dates and water, followed by a larger meal (iftar).

According to health experts, for individuals whose diabetes is well controlled, fasting may be possible with proper adjustments.

"Diabetes requires regular monitoring, balanced meals, and timely medication. When eating patterns change during Ramzan, blood glucose levels can fluctuate. That is why I strongly recommend consulting your doctor before you plan to fast,” Dr. Saptarshi Bhattacharya, Senior Consultant, Endocrinology, Indraprastha Apollo Hospitals, told HealthandMe.

The expert advised people not to skip sehri, and to include complex carbohydrates such as whole grains, along with protein like eggs, dal, or curd, and plenty of fluids to help maintain stable glucose levels throughout the day.

At iftar, avoid overeating. Start with light, balanced food and limit fried items, sweets, and sugary drinks, as these can cause a sudden spike in blood glucose, Dr. Bhattacharya said.

Type 2 Diabetes patients with good glycemic control, lifestyle management, or stable oral medications can fast safely.

However, those on multiple insulin doses, with complications, or with poor control are considered moderate to high risk, Dr. Kartik Thakkar, Consultant Medicine, Ruby Hall Clinic, told HealthandMe.

The health expert also noted that most Type 1 diabetes patients are considered high risk, especially those with brittle diabetes, frequent hypoglycemia (low blood sugar), or a history of diabetic ketoacidosis (DKA). Many are medically advised not to fast, particularly if glucose control is unstable.

Children and adolescents with type 1 diabetes are considered high risk and are usually advised against fasting due to the unpredictable nature of insulin requirements.

Who Should Avoid Fasting Altogether?

• People with a history of severe hypoglycemia in the last 3 months;
• Recurrent hypoglycemia;
• Advanced kidney disease;
• Elderly patients with frailty; and
• Pregnant women with diabetes

Dr. Thakkar said that such individuals fall into the very high-risk category and are medically exempt from fasting.

The expert also suggested clinical tests to determine whether a diabetic patient is fit to fast. These include:

• Glycemic control (HbA1c levels)
• Duration of diabetes (long-standing diabetes can increase complication risk)
• Presence of complications (neuropathy, nephropathy, cardiovascular disease)
• Kidney function and hydration status

What Warning Signs Should Prompt Breaking The Fast Immediately?

A diabetic patient must break the fast if:

• Blood glucose <70 mg/dL (3.9 mmol/L)
• Blood glucose >300 mg/dL (16.7 mmol/L)
• Severe dizziness or fainting
• Confusion or blurred vision
• Persistent vomiting
• Symptoms of dehydration (extreme thirst, very low urine output)
• Chest pain or breathlessness