Many diseases share the same symptoms, causing people to get confused and either undermine or overwhelm themselves with worries. With the current flu season on the rise, people in the United States are being very careful about their health and are taking necessary precautions to make sure they do not catch any more respiratory illnesses. Often these diseases show symptoms like coughing and wheezing, nothing that warrants anything more than a general doctor’s visit, sometimes people even think it it is a simple cold, but it could be something worse!
The Centers For Disease Control and Prevention (CDC) report on 28 February, last Friday on Respiratory Virus Activity Levels reported a moderate number of people are seeking medical help for respiratory illnesses. The flu is sending many people to the emergency room, RSV Respiratory syncytial virus has been sending many people to the ER along with COVID-19.
While flu test results are slightly less positive than last week, COVID-19 and RSV test results are about the same. In our community's wastewater, the flu virus is still very high, COVID-19 is moderate, and RSV is low. Looking forward, we expect COVID-19 emergency room visits to stay low. While flu visits are still high, they should start to go down soon.
So, even though it might feel like winter is ending, these viruses are still active, and we need to be careful. They are not going away quickly and can still spread easily. Here are some symptoms that should be treated with urgency right now.
When you're really sick, you might not feel like eating or drinking. This can lead to dehydration, which is when your body doesn't have enough water. If your pee is dark yellow, or you feel dizzy, you might be dehydrated. If you pass out, get confused, or your heart beats really fast, you need to go to the hospital right away. Healthcare professionals can give you fluids through a needle to help you feel better. Being dehydrated is very dangerous, and it is important to take it seriously.
If you're having trouble breathing, or if you're breathing really fast, that's a big sign. It could mean that you have pneumonia or that your body isn't getting enough oxygen. Shortness of breath is always a reason to go to the emergency room. Your body is telling you that something is seriously wrong. It is very important to seek help right away. Do not wait it out at home.
If your lips or fingers start to turn blue, that means you're not getting enough oxygen. Also, if you're so tired that you can barely get out of bed, that's another sign that you need to go to the hospital. These are serious symptoms that mean your body needs help right away.
Some people are more likely to get very sick from these viruses. Pregnant people, little kids, and older adults are at higher risk. Also, people who have health problems like heart or lung disease, or people with weak immune systems, are more likely to have serious problems. Older adults are often hospitalized with the flu, COVID, and RSV. These groups need to be extra careful to avoid getting sick. It is very important that these groups get vaccinated.
RSV is especially dangerous for babies and young children. It's one of the main reasons why young kids end up in the hospital. This virus can make it very hard for them to breathe. It is very important to protect young children from this virus, especially in the first few years of their lives.
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Epilepsy is one of the most common neurological disorders and a leading cause of disability worldwide. Research has suggested that associated conditions, such as stigma, anxiety, and depression, can sometimes be more debilitating than the seizures themselves.
Stigma related to epilepsy can exist at both societal and individual levels, with many patients experiencing feelings of shame, fear, discrimination, and social isolation.
Now, research led by AIIMS New Delhi has suggested that yoga may help reduce epilepsy-related stigma while also improving seizure control. The 2023 study, published in Neurology, found that yoga-based interventions may offer benefits for both mental well-being and disease management.
“Yoga has been clinically proven to reduce the ‘felt stigma’ associated with epilepsy. By alleviating anxiety and improving both mindfulness and overall quality of life, mind-body interventions empower individuals to feel more in control and less socially isolated,” lead author Dr. Manjari Tripathi, Head of the Department of Neurology at AIIMS, told HealthandMe.
According to Dr. Manjari, the study identified three key benefits of yoga for people living with epilepsy:
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Dr. Rajesh Sagar, Professor of Psychiatry at AIIMS, told HealthandMe that yoga reduced the burden of epilepsy and improved the overall quality of life in epilepsy patients by reducing the perceived stigma. The overall quality of life was also improved in the yoga group.
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Researchers conducted a randomized clinical trial involving 160 adults with epilepsy who were followed for six months. Participants were assigned either a structured yoga program or a sham yoga intervention, while both groups also received epilepsy-related psychoeducation.
The yoga program included loosening exercises , breathing techniques, meditation, and positive affirmations.
While the impact on seizure frequency was reduced compared with the control group, the researchers cautioned that larger studies are needed to conclusively determine the effect of yoga on seizure control.
Further, mood disturbances have been common among people with epilepsy and often remain inadequately addressed, particularly in developing countries.
According to the researchers, yoga may offer a scalable and accessible option for helping patients manage these challenges alongside conventional treatment.
Dr. Rajesh further told HealthandMe that yoga has well-established benefits for mental health.
“Yoga is important in mental health care, and it has been found that the three important things, which are pranayama, that is, breathing techniques, asanas, that is, physical posture, and dhyana, that is, meditation, have a positive effect on anxiety and even depression, and also improve sleep".
He added that yoga can help reduce stress, improve mood, lower anxiety levels, and enhance sleep quality.
“There is substantial evidence from around the world showing that yoga can benefit people living with certain mental health disorders,” he said.
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Every morning, millions begin their day with a quick breakfast and blood pressure (BP) medication swallowed mechanically. But what happens when BP remains uncontrolled despite medicines? Uncontrolled hypertension is one of the most underestimated health threats. Often called the silent killer, it quietly damages the heart, brain, kidneys, and blood vessels.
The BP reading on the cuff captures only a visible measurement. BP that remains above goal over time despite treatment is concerning. Hypertension affects approximately 1.4 billion adults worldwide. Studies suggest that almost 54% of Indian patients have uncontrolled hypertension even while taking ≥2 medications. Thus, treatment does not necessarily mean control.
Global organizations recommend stricter BP targets, aiming for readings below 130/80 mmHg or even 120 mmHg if tolerated. Studies show that each 10 mmHg reduction in systolic BP can decrease the risk of major cardiovascular events by 20%, stroke by 27%, heart failure by 28%, and death by 13%.
On the other hand, uncontrolled hypertension increases the risk of heart attacks, strokes, heart failure, end-stage kidney disease, type 2 diabetes, and death.
In persistently uncontrolled hypertension that other causes cannot explain, a hidden culprit called aldosterone is an under-recognized driver. Normally, aldosterone balances sodium and water to regulate BP.
However, in patients with uncontrolled hypertension, aldosterone production may remain abnormally high, causing sodium and fluid buildup, increasing BP.
Approximately 30% of patients with hypertension may have aldosterone dysregulation, and patients with resistant hypertension, obesity, type 2 diabetes, sleep apnea, and hypokalemia are at greater risk. Nearly 10–20% of patients with hypertension are treatment resistant, increasing their risk. In these patients, aldosterone dysregulation could be an important cause.
It is time to look beyond the cuff, as uncontrolled hypertension is a chronic, progressive, and often silent condition with serious consequences. Improving patient outcomes requires greater urgency, earlier intervention, better treatment optimization, and stronger awareness of underlying drivers such as aldosterone.
It is time to identify and treat the root causes of uncontrolled hypertension, so that patients can regain lasting BP control.
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Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, affects millions of people worldwide. The lifelong condition commonly begins in adolescence or early adulthood and can require repeated hospital treatment, long-term immunosuppressive medication, and, in some cases, surgery.
Despite advances in treatment, many patients cycle through multiple therapies without achieving lasting disease control, impacting their lives and costing healthcare systems millions.
Now, a team of UK researchers from the Universities of Oxford, Newcastle, and Cambridge has identified an important driver of inflammatory bowel disease (IBD).
The findings, published in the New England Journal of Medicine, suggest that inflammatory bowel disease is not a single condition but a group of biologically distinct diseases driven by different underlying mechanisms.
"Understanding what drives the inflammation provides a clear explanation for disease in this group of people and opens the door to new treatments that target the autoantibodies themselves or cells that produce those autoantibodies," said Professor Holm Uhlig, a pediatric gastroenterologist and director of the Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford.
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The researchers analyzed more than 4,900 patients with IBD and discovered that:
Antibodies that block interleukin-10 (IL-10), a cell-to-cell messenger that normally acts as one of the body's key controls on inflammation, effectively remove the immune system's natural "brake" on inflammation, allowing inflammatory responses to continue unchecked.
The researchers found high levels of anti-IL-10 neutralizing autoantibodies in the blood of about 3.5% of IBD patients, including those with Crohn's disease and ulcerative colitis, but not in healthy individuals. This could equate to 15,000–20,000 people with IBD in the UK carrying these autoantibodies.
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The researchers also found that the presence of these antibodies was strongly linked to carriage of a particular genetic variant known as HLA-DRB1*01:03.
The link between HLA-DRB1*01:03 and a severe form of inflammatory bowel disease was first identified by Oxford researchers 30 years ago.
The new findings show that people carrying this variant are far more likely to develop antibodies that block IL-10, helping explain how the gene contributes to disease.
The researchers say the findings support the development of a blood test to identify this subgroup of patients, helping clinicians move quickly toward more appropriate treatment.
As per the Centers for Disease Control and Prevention (CDC), IBD refers to a group of lifelong diseases that affect your intestines. The main types of IBD are ulcerative colitis and Crohn's disease.
Ulcerative colitis affects the large intestine, while Crohn’s disease can inflame any part of the digestive tract. Both are lifelong conditions of unknown cause that trigger abdominal pain, diarrhea and other complications, with no known cure.
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