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Stress is an unavoidable part of life, and while it often carries a negative connotation, it is actually a fundamental survival mechanism. When faced with a perceived threat, whether physical or emotional, the body instinctively reacts to protect itself. This automatic response is commonly known as the "fight, flight, or freeze" response. While it serves an essential function in dangerous situations, chronic activation of this response due to daily stressors can have significant consequences for mental and physical health.
The body’s response to stress is rooted in human evolution. When our ancestors encountered a predator, their nervous systems immediately prepared them to either confront the threat (fight), escape to safety (flight), or become still and unnoticed (freeze). While modern-day stressors may not include wild animals, our nervous system reacts similarly to job pressures, financial worries, or social conflicts.
According to the Cleveland Clinic, stress is the body's response to change, activating a physiological reaction that helps us adapt and protect ourselves. While short-term stress can be beneficial, prolonged exposure can lead to an overactive stress response, negatively impacting overall well-being.
The fight response prepares the body for direct action. When triggered, the nervous system releases adrenaline, increasing heart rate, blood pressure, and muscle tension. While this reaction once helped early humans fend off predators, today it manifests as irritability, frustration, or aggression.
For instance, the employee who has experienced too much workload may work extremely long hours just to succeed. In short term, the action may produce good results but mostly ends in burnout, anxiety, and physical illness, for example, tension headache or digestion problems.
The flight response triggers an intense need to remove oneself from a stressful situation. Just as our ancestors would flee from danger, modern individuals may avoid conflict, quit jobs impulsively, or detach from relationships when overwhelmed.
Flight mode is linked with restlessness and anxiety. Individuals may have a sense of needing to get up and go-pacing, changing environments constantly, or avoiding tasks that seem too overwhelming. Someone with a flight response might have the desire to change jobs constantly, relocate constantly, or become reclusive in order to avoid perceived dangers.
The freeze response occurs when the nervous system perceives a threat as too overwhelming to fight or flee. Rather than taking action, individuals shut down, feeling numb, disconnected, or paralyzed by fear.
Unlike fight or flight, which involve heightened activation, freeze mode slows down physiological functions. A person experiencing freeze mode may feel physically unable to move, struggle to make decisions, or find themselves dissociating from their emotions. This can manifest in situations such as public speaking anxiety, where someone might "blank out" or feel stuck in the moment.
When faced with a stressor, the autonomic nervous system (ANS) activates, triggering physiological changes, including:
For those experiencing the freeze response, the body undergoes a different reaction, often reducing heart rate and causing physical immobility rather than heightened activation.
While the stress response is necessary for survival, frequent activation due to daily stressors can take a toll on health. Recognizing your default response—whether fight, flight, or freeze—can help in developing effective coping mechanisms.
If possible, changing your environment can help signal to your brain that the threat has passed. Stepping outside for fresh air, finding a quiet place, or distancing yourself from overwhelming stimuli can help regulate emotions.
Deep, slow breathing can be used to counteract the stress response by engaging the parasympathetic nervous system, which promotes relaxation. Techniques such as diaphragmatic breathing or the 4-7-8 method (inhale for four seconds, hold for seven, exhale for eight) can be particularly effective in calming the body.
This helps release pent-up energy and aids in the endorphin cascade, natural boosters for our mood.
Relieving oneself from stress can come in many ways, but sharing it with trusted friends, a family member, or a good therapist will sure give that psychological boost of hope. Social support is an especially effective way of cushioning people against the stressors that they are subjected to in chronic forms.
While occasional stress is normal, chronic activation of the fight, flight, or freeze response can indicate underlying mental health concerns, such as anxiety disorders or post-traumatic stress disorder (PTSD). If stress is affecting daily life—leading to sleep disturbances, difficulty concentrating, or persistent feelings of fear—it may be time to consult a mental health professional.
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American stand-up comedian and actress Amy Schumer has opened up on her colonoscopy procedure didn’t go quite as planned.
Speaking at the Not Skinny But Not Fat podcast, the 44-year-old Amy Schumer stated that she’s feeling "happier than I've ever been before," but admitted that she's also been experiencing some struggles.
“I actually had kind of a botched colonoscopy, so I’m not feeling very sexual,” she noted.
Schumer, who filed for an uncontested divorce with her husband of seven years, Chris Fischer, in January, reportedly didn't share any further details.
Previously, the Trainwreck star shared major insight into her health journey over the years—including how her diagnosis with Cushing Syndrome influenced her weight loss journey.
“I didn’t lose 30lbs, I lost 50,” Amy wrote in a post on social media platform Instagram. “Not to look hot which does feel fun and temporary. I did it to survive. I had a disease that makes your face extremely puffy and can kill you but the internet caught it and that disease has cleared.”
Cushing Syndrome is a hormonal condition that causes elevated levels of cortisol, and can cause death if left untreated, as per the National Library of Medicine.
Amy has also spoken of losing weight by using Mounjaro and her physical transformation via plastic surgery.
"I have been working to be pain free and I finally am," she wrote in a November Instagram post. “My endometriosis is better. My back is healing. I no longer have Cushing syndrome so my face went back to normal. I am grateful to be strong and healthy, especially for my son.”
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A colonoscopy is a 15 to 60 minute medical procedure that is used to examine the entire inner lining of the large intestine, which includes rectum and colon for abnormalities, such as polyps, inflammation, or cancer.
A doctor uses a colonoscope, which is a thin, flexible tube with a camera to take images, remove polyps, or take issue samples.
Most health experts, including federal guidelines and the American Cancer Society, recommend that people at average risk for colorectal cancer start screening at age 45. This usually means getting a colonoscopy once every 10 years, or opting for stool-based tests every one to three years. These guidelines also play a role in whether insurance companies cover the tests.
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Even so, most cases of colon cancer are still diagnosed in people over 50. What’s worrying, though, is the steady rise in cases among younger adults in their 20s, 30s and 40s over the past few decades.
Access to colonoscopies remains a concern, especially in low and middle income countries. Further, screening rates among younger eligible adults remain low. Only about one in five people aged 44 to 49 are up to date with recommended screenings.
Experts say that if the screening age were lowered further, participation might drop even more. For now, the focus remains on improving awareness and encouraging those already eligible to get screened on time.
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Feeling anxious, unable to perform well, and feeling burnt out at the workplace is a common problem facing employees slogging for over nine hours every day. But now, a study suggests that taking short vacations every two months can help reduce stress accumulation.
In a 2025 research paper titled “Maximizing Recovery: The Superiority of Frequent Vacations”, Selvaraj Giridharan from the Oncology Department at Tawam Hospital in Abu Dhabi suggests that taking short breaks can help improve mental well-being and boost work performance.
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The study argued that instead of a long annual vacation, frequent short breaks are often more effective and help people mentally detach from work. This also helps them recover from burnout faster.
Researchers also found that the positive effects of vacations usually fade within a few weeks after returning to work, making regular breaks important for maintaining emotional balance and productivity.
"We emphasize how regular vacations facilitate recovery and enhance well-being, thereby reducing stress and improving performance. We advocate the integration of frequent breaks into workplace culture through practical strategies for both individuals and organizations," wrote study author Selvaraj Giridharan.
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Amid discussions around 70-hour work weeks advocated by industrialists like Narayana Murthy, the study comes as a breather.
The researchers, including experts from the National Health Service, stressed that sustained work-related stress causes significant psychobiological strain. This depletes physiological and psychological resources, manifesting as elevated cortisol levels, cognitive fatigue, and emotional exhaustion.
Without periodic recovery, this strain accumulates, increasing the risk of burnout, reduced productivity, and adverse health outcomes. India has seen several recent cases where workplace stress has affected people’s mental health, with some collapsing at work while others resorted to suicide.
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The paper cited a meta-analysis of 22 studies that showed that vacations provide substantial psychological, physiological, and cognitive benefits.
It noted post-vacation reductions in exhaustion, improvements in mood, and increases in life satisfaction among employees.
The findings were found consistent with several studies which identified physiological improvements, including reduced cortisol levels, enhanced heart rate variability, and better sleep quality. These outcomes reflect mitigation of the physiological burden of chronic stress and position vacations as vital health interventions.
The researcher stated that vacations are essential for mitigating the psychobiological impacts of contemporary work and providing psychological, physiological, and cognitive advantages.
Although the duration of vacations is significant, frequent and shorter vacations are more effective in maintaining well-being through regular recovery, they said.
"This evidence-based perspective, rooted in effort-recovery theory, advocates strategic vacation planning by organisations and policymakers to prioritise workforce health. Societies should promote vacation policies that emphasise frequency in order to enhance employee well-being and performance,” the paper said.
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In India, poor reproductive health awareness remains one of the most overlooked gaps in women’s healthcare. Many women continue to ignore gynecological symptoms, assuming them to be routine, temporary, or too embarrassing to discuss.
Persistent vaginal infections, irregular bleeding, untreated hormonal disorders, chronic pelvic pain, or recurring inflammation are often dismissed until they become severe. In some cases, these untreated or undiagnosed conditions can silently contribute to long-term health risks, including certain cancers.
Today, many women have heard of conditions like PCOS, endometriosis, or fibroids. But awareness is often incomplete. Women may know the name of a condition, yet not know its warning signs, complications, or when medical attention is necessary.
For example, prolonged hormonal imbalance, obesity, irregular periods, and chronic inflammation may increase the risk of certain gynecological cancers over time. Similarly, lack of awareness about HPV, cervical screening, and vaccination continues to delay prevention and early diagnosis of cervical cancer.
Fertility awareness is another important gap. Many women are not familiar with their menstrual cycle, ovulation pattern, or normal reproductive changes. When women do not know what is normal for their own body, it becomes harder to recognize when something is wrong.
Social media has added another layer to this problem. While it has improved access to health information, it has also created confusion. Quick tips, unverified remedies, and incomplete advice can delay proper diagnosis and treatment.
Reproductive literacy is not just about knowing symptoms. It means understanding one’s body, menstrual cycle, sexual health, fertility, contraception, screening options, vaccination, and access to safe healthcare.
Unfortunately, stigma around sexual and reproductive health still prevents many women from seeking timely care. Symptoms such as abnormal discharge, bleeding after intercourse, pelvic pain, or irregular bleeding are often hidden out of fear, shame, or hesitation.
This delay is especially dangerous in cancers such as cervical, uterine, ovarian, and vaginal cancers, where early evaluation can make a major difference.
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