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Stress is an unavoidable part of life, and while it often carries a negative connotation, it is actually a fundamental survival mechanism. When faced with a perceived threat, whether physical or emotional, the body instinctively reacts to protect itself. This automatic response is commonly known as the "fight, flight, or freeze" response. While it serves an essential function in dangerous situations, chronic activation of this response due to daily stressors can have significant consequences for mental and physical health.
The body’s response to stress is rooted in human evolution. When our ancestors encountered a predator, their nervous systems immediately prepared them to either confront the threat (fight), escape to safety (flight), or become still and unnoticed (freeze). While modern-day stressors may not include wild animals, our nervous system reacts similarly to job pressures, financial worries, or social conflicts.
According to the Cleveland Clinic, stress is the body's response to change, activating a physiological reaction that helps us adapt and protect ourselves. While short-term stress can be beneficial, prolonged exposure can lead to an overactive stress response, negatively impacting overall well-being.
The fight response prepares the body for direct action. When triggered, the nervous system releases adrenaline, increasing heart rate, blood pressure, and muscle tension. While this reaction once helped early humans fend off predators, today it manifests as irritability, frustration, or aggression.
For instance, the employee who has experienced too much workload may work extremely long hours just to succeed. In short term, the action may produce good results but mostly ends in burnout, anxiety, and physical illness, for example, tension headache or digestion problems.
The flight response triggers an intense need to remove oneself from a stressful situation. Just as our ancestors would flee from danger, modern individuals may avoid conflict, quit jobs impulsively, or detach from relationships when overwhelmed.
Flight mode is linked with restlessness and anxiety. Individuals may have a sense of needing to get up and go-pacing, changing environments constantly, or avoiding tasks that seem too overwhelming. Someone with a flight response might have the desire to change jobs constantly, relocate constantly, or become reclusive in order to avoid perceived dangers.
The freeze response occurs when the nervous system perceives a threat as too overwhelming to fight or flee. Rather than taking action, individuals shut down, feeling numb, disconnected, or paralyzed by fear.
Unlike fight or flight, which involve heightened activation, freeze mode slows down physiological functions. A person experiencing freeze mode may feel physically unable to move, struggle to make decisions, or find themselves dissociating from their emotions. This can manifest in situations such as public speaking anxiety, where someone might "blank out" or feel stuck in the moment.
When faced with a stressor, the autonomic nervous system (ANS) activates, triggering physiological changes, including:
For those experiencing the freeze response, the body undergoes a different reaction, often reducing heart rate and causing physical immobility rather than heightened activation.
While the stress response is necessary for survival, frequent activation due to daily stressors can take a toll on health. Recognizing your default response—whether fight, flight, or freeze—can help in developing effective coping mechanisms.
If possible, changing your environment can help signal to your brain that the threat has passed. Stepping outside for fresh air, finding a quiet place, or distancing yourself from overwhelming stimuli can help regulate emotions.
Deep, slow breathing can be used to counteract the stress response by engaging the parasympathetic nervous system, which promotes relaxation. Techniques such as diaphragmatic breathing or the 4-7-8 method (inhale for four seconds, hold for seven, exhale for eight) can be particularly effective in calming the body.
This helps release pent-up energy and aids in the endorphin cascade, natural boosters for our mood.
Relieving oneself from stress can come in many ways, but sharing it with trusted friends, a family member, or a good therapist will sure give that psychological boost of hope. Social support is an especially effective way of cushioning people against the stressors that they are subjected to in chronic forms.
While occasional stress is normal, chronic activation of the fight, flight, or freeze response can indicate underlying mental health concerns, such as anxiety disorders or post-traumatic stress disorder (PTSD). If stress is affecting daily life—leading to sleep disturbances, difficulty concentrating, or persistent feelings of fear—it may be time to consult a mental health professional.
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The COVID pandemic was a disastrous time for human civilization. The effects of that time are still observable to this day. The lockdown and other aspects of the period affected every stratum of society and life. And one of the most impacted sectors was the health care sector, which was at the forefront of the global crisis. Thus, other routine healthcare, as important as cancer, got neglected and caused pain and despair.
A recent study by the International Agency for Research on Cancer in Lyon, France, published in The Lancet Oncology, sheds light on the magnitude of the healthcare disruption during the pandemic, as the research finds there were 55,000 cancers that remained undiagnosed due to the spread of COVID. The largest estimation at an international scale observed data from 2.6 million patients and 18 jurisdictions.
The researchers saw that developed first-world countries like Norway and New Zealand suffered due to the crisis, though the health care systems there saw a smaller decline, which was followed by faster recovery. On the other side, even developed and economic powerhouses like the United Kingdom, Canada, and Australia got the worst of it, and recovery was also slower.
According to the study, 16 percent of the cancer cases remained undiagnosed in nations like Australia, Canada, Denmark, Ireland, New Zealand, Norway, and the UK between April and December 2020. Though the biggest dip was seen in prostate cancer diagnoses, which fell by a massive 24 percent, followed by breast cancer and melanoma, both down 18 percent.
Isabelle Soerjomataram, deputy head of the agency’s Cancer Surveillance Branch and the study’s senior author, said, “A more detailed understanding of why some health systems were better able to withstand the pressures of the Covid-19 pandemic could provide valuable lessons for future crisis preparedness.”
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The gland in the male reproductive system that makes seminal fluid is the prostate. This is the most common type of slow-growing cancer in men, which sees the abnormal growth of cells in the gland; if detected early, it is very much curable. Some early-stage symptoms of the disease are blood in the urine or semen, trouble urinating, and erectile dysfunction, and if you’re asking yourself, why you?
You could probably blame age, family history or lifestyle choices. While we cannot change the ‘why’, we can master the ‘how’ of finding the right treatment in time. Step 1: Rule out the possibility of cancer with a simple Prostate-Specific Antigen (PSA) blood test.
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Melanoma is a type of skin cancer that develops in melanocytes, the cells responsible for producing melanin, the pigment that gives skin its colour. It can occur anywhere on the skin but often develops on areas exposed to the sun, such as the face, arms, back, and legs. Melanoma can also appear in less-exposed areas, like the soles of the feet, palms, or under the nails, particularly in individuals with darker skin tones. Although rare, melanoma may develop in the eyes, mouth, or internal organs. The primary sign of melanoma is a new or changing mole, freckle, or skin lesion.
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Mental health is a very important aspect of life, and the society at large, but a recent survey has shed light on the current state of mental health in adolescents and young adults. The survey of RAND was published in the journal JAMA Pediatrics. The survey finds that 1 in 5 adolescents and young people is using an AI chatbot for mental health.
The organization also did a similar survey back in 2025, but then about 13% of respondents admitted to using a chatbot for advice; that number has jumped up to 19% this year. The 63% of them confessed that they did not tell anyone about taking therapy from a chatbot.
Ryan McBain, a senior policy researcher at RAND and the lead author of the study, said, “It’s a sad number, because you’d hope that young people would have the sorts of supportive relationships that they would feel comfortable and empowered reaching out to those around them.”
McBain and his team asked people aged between 12 and 21 years about their use of AI chatbots, including ChatGPT, Google Gemini, or Character.AI, for mental health advice. They also asked whether the advice from the chatbots was helpful, and the majority of participants felt that the suggestions were useful.
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Over one million Americans have contracted chronic hepatitis B and are now forced to go through a lifelong treatment process. Though these treatment only helps in terminating the virus, the risk of liver cancer stays on, and the constant fear and torment remain. Now, a new study of a drug trial for hepatitis B patients has given hope to millions.
The trial saw 1 in 5 patients with chronic hepatitis B infection getting cured. The 24-week test had 1,838 patients from 29 countries in Asia, Europe, and North and South America. The research published in the New England Journal of Medicine concluded that 20% of patients got a functional cure, and no virus was detected in them after 48 hours.
The drug, bepirovirsen, is made by Ionis Pharmaceuticals and GlaxoSmithKline and can stop the virus from replicating itself while giving the immune system a chance to eradicate it. The treatment process will be done by administering an injection once a week. Notably, GlaxoSmithKline has already applied to the Food and Drug Administration for approval to market the drug.
Though there was an option of vaccination to prevent the disease, still, millions are infected. This effective functional cure option will be a great addition to the treatment of hepatitis B.
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Hepatitis B is a viral infection that affects the liver. Many adults can clear the virus after an acute infection. Some, however, go on to develop chronic hepatitis B, which increases the risk of liver cancer, liver failure, and cirrhosis, or permanent scarring of the liver.
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The hepatitis B virus is highly contagious. It spreads when blood, semen, or other bodily fluids from a person who carries the virus enter the body of someone who is not infected.
Certain medical conditions, personal habits, and other circumstances can raise the risk, such as injection drug use or sexual contact, but the virus can infect anyone. Hepatitis B can also pass from an infected mother to her baby during childbirth, whether through a vaginal delivery or a C-section.
Vaccination is the most reliable way to prevent hepatitis B. The shots offer strong protection in infancy and continue to shield individuals well into adulthood. Babies usually receive a three-dose series.
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