Stress is an unavoidable part of life, and while it often carries a negative connotation, it is actually a fundamental survival mechanism. When faced with a perceived threat, whether physical or emotional, the body instinctively reacts to protect itself. This automatic response is commonly known as the "fight, flight, or freeze" response. While it serves an essential function in dangerous situations, chronic activation of this response due to daily stressors can have significant consequences for mental and physical health.

The body’s response to stress is rooted in human evolution. When our ancestors encountered a predator, their nervous systems immediately prepared them to either confront the threat (fight), escape to safety (flight), or become still and unnoticed (freeze). While modern-day stressors may not include wild animals, our nervous system reacts similarly to job pressures, financial worries, or social conflicts.

According to the Cleveland Clinic, stress is the body's response to change, activating a physiological reaction that helps us adapt and protect ourselves. While short-term stress can be beneficial, prolonged exposure can lead to an overactive stress response, negatively impacting overall well-being.

The Three Stress Responses: Fight, Flight, and Freeze

1. Fight

The fight response prepares the body for direct action. When triggered, the nervous system releases adrenaline, increasing heart rate, blood pressure, and muscle tension. While this reaction once helped early humans fend off predators, today it manifests as irritability, frustration, or aggression.

For instance, the employee who has experienced too much workload may work extremely long hours just to succeed. In short term, the action may produce good results but mostly ends in burnout, anxiety, and physical illness, for example, tension headache or digestion problems.

2. Fight

The flight response triggers an intense need to remove oneself from a stressful situation. Just as our ancestors would flee from danger, modern individuals may avoid conflict, quit jobs impulsively, or detach from relationships when overwhelmed.

Flight mode is linked with restlessness and anxiety. Individuals may have a sense of needing to get up and go-pacing, changing environments constantly, or avoiding tasks that seem too overwhelming. Someone with a flight response might have the desire to change jobs constantly, relocate constantly, or become reclusive in order to avoid perceived dangers.

3. Freeze

The freeze response occurs when the nervous system perceives a threat as too overwhelming to fight or flee. Rather than taking action, individuals shut down, feeling numb, disconnected, or paralyzed by fear.

Unlike fight or flight, which involve heightened activation, freeze mode slows down physiological functions. A person experiencing freeze mode may feel physically unable to move, struggle to make decisions, or find themselves dissociating from their emotions. This can manifest in situations such as public speaking anxiety, where someone might "blank out" or feel stuck in the moment.

What Happens in the Body During A Stressful Event?

When faced with a stressor, the autonomic nervous system (ANS) activates, triggering physiological changes, including:

• Increased heart rate and breathing: The body pumps more oxygen to muscles and the brain in case action is needed.
• Muscle tension: The body prepares for movement, sometimes causing trembling or stiffness.
• Dilated pupils: Vision sharpens to detect potential threats.
• Dry mouth: Saliva production decreases as the body redirects energy to essential functions.
• Changes in skin tone: Blood flow is directed to vital organs, sometimes making the skin appear pale or flushed.

For those experiencing the freeze response, the body undergoes a different reaction, often reducing heart rate and causing physical immobility rather than heightened activation.

Strategies for Coping and Managing the Stress Response

While the stress response is necessary for survival, frequent activation due to daily stressors can take a toll on health. Recognizing your default response—whether fight, flight, or freeze—can help in developing effective coping mechanisms.

1. Moving to a Safe Space

If possible, changing your environment can help signal to your brain that the threat has passed. Stepping outside for fresh air, finding a quiet place, or distancing yourself from overwhelming stimuli can help regulate emotions.

2. Practicing Controlled Breathing

Deep, slow breathing can be used to counteract the stress response by engaging the parasympathetic nervous system, which promotes relaxation. Techniques such as diaphragmatic breathing or the 4-7-8 method (inhale for four seconds, hold for seven, exhale for eight) can be particularly effective in calming the body.

3. Engaging in Physical Activity

This helps release pent-up energy and aids in the endorphin cascade, natural boosters for our mood.

4. Seeking Social Support

Relieving oneself from stress can come in many ways, but sharing it with trusted friends, a family member, or a good therapist will sure give that psychological boost of hope. Social support is an especially effective way of cushioning people against the stressors that they are subjected to in chronic forms.

When to Seek Professional Help

While occasional stress is normal, chronic activation of the fight, flight, or freeze response can indicate underlying mental health concerns, such as anxiety disorders or post-traumatic stress disorder (PTSD). If stress is affecting daily life—leading to sleep disturbances, difficulty concentrating, or persistent feelings of fear—it may be time to consult a mental health professional.

Heart attacks are often associated with severe chest pain, but health experts warned that many cases present with unusual symptoms such as jaw pain and nausea that are frequently ignored or mistaken for less serious conditions.

Ischemic Heart Disease (IHD) or heart attacks is the leading cause of death worldwide, responsible for roughly 9 million deaths annually

Speaking to HealthandMe, the experts highlighted unusual symptoms that may indicate a heart attack — particularly in women, elderly people, and individuals with diabetes. These include:

• Jaw pain
• Nausea
• Sweating
• Dizziness
• Unusual fatigue
• Breathlessness
• Discomfort in the neck, back, or arms

Ignoring Symptoms Can Worsen Outcomes

Dr. Prasanthi Ganji, HOD - Emergency Medicine at Manipal Hospital, Gurugram, called these “referred symptoms”, where pain from the heart travels through shared nerve pathways and is felt in other parts of the body, including the jaw, neck, shoulders, or back.

The expert explained that nausea may occur because reduced blood flow and stress on the heart can affect the nervous system and digestive response.

Also read: Can Extreme Heat Trigger Heart Palpitations? Expert Explains Risks

According to her, many patients mistake these symptoms for acidity, fatigue, or muscle strain, leading to dangerous delays in treatment.

“Recognizing these warning signs during the critical golden hour can significantly improve survival and reduce long-term heart damage,” Dr. Prasanthi told HealthandMe, adding that symptoms lasting more than a few minutes should never be ignored.

Heart Attack: Silent Symptoms Often Overlooked

Dr. Saifa M. Latheef, Associate Professor and Clinical Head – Emergency Medicine at ShardaCare-Healthcity, said public awareness about silent or unusual heart attack symptoms remains low.

“Many people believe that a heart attack always causes severe chest pain. However, this is not true in every case,” she said.

Dr. Saifa noted that some patients may experience heaviness in the jaw, vomiting sensation, breathlessness, or extreme weakness without chest pain, causing them to delay emergency care.

“A heart attack occurs when blood flow to the heart suddenly gets blocked, making immediate medical attention crucial to save heart muscle and prevent complications,” the doctor told HealthandMe.

Doctors Warn Against Delaying Treatment

The health experts also flagged the delaying attitude of patients, which increases the risk of poorer outcomes.

Dr. Nitin Jagasia, Regional Director Emergency, Western Region, Apollo Hospitals, said the biggest mistake patients make is waiting too long before seeking help.

“As an emergency doctor, I meet patients every day who say, ‘Doctor, I thought it would go away,’” he told HealthandMe.

Dr. Jagasia warned that heart attacks do not always begin with crushing chest pain and that unusual symptoms like nausea, sweating, stomach discomfort, or unexplained fatigue are often mistaken for acidity or stress.

“A simple rule to remember is this: if a symptom is sudden, severe, or frightening, do not wait for it to pass,” he said.

Read More: Early Exposure To Lead And Lithium Can Cause A Lifetime Of Mental Exhaustion

How To Prevent

The experts emphasized that timely treatment, CPR awareness, and rapid emergency response remain the strongest defences against sudden cardiac emergencies.

They also highlighted the importance of preventive measures such as regular exercise, healthy eating, stress management, quitting smoking, and controlling diabetes and blood pressure.

Obesity is a very significant modifiable risk factor for brain stroke, which is an extremely dangerous illness caused by an insufficient or lack of blood supply to the brain. Stroke leads to disability, memory impairment, paralysis, and sometimes death. As obesity is related to many illnesses, regulation of weight can considerably decrease the probability of suffering a brain stroke.

Dr Bhupesh Kumar Mansukhani, Director of Neurology at Neuromet Wellness Care & Diagnostics, in an interview with Health and Me, said, "Obesity is an excessive accumulation of fat in the body, which causes damage to health. Obesity is determined using the BMI index. Those who suffer from obesity are more prone to illnesses like hypertension, diabetes, and elevated cholesterol levels, all of which put people at a higher risk of suffering a brain stroke. Excessive fat, particularly abdominal fat, affects the arteries, leading to their constriction."

Can hypertension trigger a stroke?

Hypertension, or high blood pressure, is yet another major connection between obesity and stroke. Obesity causes stress on the cardiovascular system and elevates blood pressure levels. Such a state poses a risk of injury to the blood vessels in the brain, causing their rupture or blockage. Obesity usually results in diabetes, and both conditions harm the walls of the blood vessels and increase the risk of blood clot formation. Besides, the increased concentration of cholesterol contributes to plaque accumulation in the arteries.

The presence of obesity in the body stimulates inflammatory reactions and reduces the rate of circulation, which may cause the formation of blood clots. As a result, these clots are delivered to the brain and prevent blood from delivering oxygen to it, and ischaemia becomes the trigger for an ischaemic stroke, which is the leading type of stroke.

Is obesity a modifiable risk factor?

The advantage here is that obesity is a modifiable risk factor, which can actually be avoided or managed. Proper nutrition, physical exercise, adequate sleep, and the absence of negative behaviours will enable an individual to maintain a healthy body weight. It is also important to take part in preventive measures, such as having regular medical examinations and testing one’s blood pressure, glucose levels, and cholesterol.

To conclude, it can be noted that obesity contributes significantly to increased risks of developing a brain stroke due to many reasons, including hypertension, diabetes mellitus, and vascular diseases. Being a modifiable risk factor, it can be easily avoided.

Cancer is, without a doubt, one of the most feared diseases known to man. According to the Indian Council of Medical Research - National Cancer Registry Programme (ICMR-NCRP), India gets 1.5 million new cases of the disease every year, with one in nine people likely to develop cancer in their lifetime. On the other hand, the American Cancer Society (ACS) and National Cancer Institute (NCI) expect about 2,114,850 new cases in the United States this year alone.

A new study claims that the weight loss drug, glucagon-like peptide-1 (GLP-1), may help slow the spread of some cancers. The research was done by the Cleveland Clinic and claimed that the medications may slow down the spread of several obesity-related cancers, including lung, breast, colorectal, and liver cancers.

The official press release by the Cleveland Clinic mentions their research being included 12,112 patients with the following types of obesity-related cancers, ranging from stage 1 to stage 3, and half of these participants started a GLP-1 medication after their cancer diagnosis. The others were taking a DPP-4 inhibitor comparator, "gliptins," a different class of diabetes medications.

The comparison between the two groups clearly shows that the patients who took GLP-1 have a much lower progression to stage 4 disease for four types of cancers.

The study author, Mark David Orland, MD, of the Taussig Cancer Institute at Cleveland Clinic, said, "Our study found that use of GLP-1 drugs, compared to DPP-4 inhibitors and other antidiabetic drugs, was associated with a meaningful reduction in cancer progression across four solid tumor types."

How To Reduce The Risk Of Cancer?

• Consuming a healthy and balanced diet rich in fruits, vegetables, whole grains, and lean proteins can reduce cancer risk.
• Regular physical activity keeps the body fit and reduces the risk of breast, colon, and endometrial cancers.
• Smoking and alcohol consumption should be avoided.
• Skin cancer is one of the most preventable types of cancer. Applying sunscreen with high SPF, finding shade, and avoiding tanning beds would save you from harmful ultraviolet rays.
• Long-term stress can weaken the immune system and may contribute to an increased risk of cancer. Incorporating stress-relief techniques such as mindfulness, practising deep-breathing exercises, and engaging in enjoyable hobbies can enhance overall well-being.
• Exposure to environmental elements like pesticides, pollutants, and workplace chemicals can increase the risk of cancer. To avoid this risk, wearing protective gear, opting for organic produce, and ensuring adequate ventilation in living or working areas can greatly assist.
• By vaccinating against Hepatitis B and HPV, individuals can protect themselves against infections closely linked to liver and cervical cancers; apart from vaccination, adopting proper hygiene practices and steering clear of high-risk activities can help prevent the risk of cancer-causing infections.