Stress is an unavoidable part of life, and while it often carries a negative connotation, it is actually a fundamental survival mechanism. When faced with a perceived threat, whether physical or emotional, the body instinctively reacts to protect itself. This automatic response is commonly known as the "fight, flight, or freeze" response. While it serves an essential function in dangerous situations, chronic activation of this response due to daily stressors can have significant consequences for mental and physical health.

The body’s response to stress is rooted in human evolution. When our ancestors encountered a predator, their nervous systems immediately prepared them to either confront the threat (fight), escape to safety (flight), or become still and unnoticed (freeze). While modern-day stressors may not include wild animals, our nervous system reacts similarly to job pressures, financial worries, or social conflicts.

According to the Cleveland Clinic, stress is the body's response to change, activating a physiological reaction that helps us adapt and protect ourselves. While short-term stress can be beneficial, prolonged exposure can lead to an overactive stress response, negatively impacting overall well-being.

The Three Stress Responses: Fight, Flight, and Freeze

1. Fight

The fight response prepares the body for direct action. When triggered, the nervous system releases adrenaline, increasing heart rate, blood pressure, and muscle tension. While this reaction once helped early humans fend off predators, today it manifests as irritability, frustration, or aggression.

For instance, the employee who has experienced too much workload may work extremely long hours just to succeed. In short term, the action may produce good results but mostly ends in burnout, anxiety, and physical illness, for example, tension headache or digestion problems.

2. Fight

The flight response triggers an intense need to remove oneself from a stressful situation. Just as our ancestors would flee from danger, modern individuals may avoid conflict, quit jobs impulsively, or detach from relationships when overwhelmed.

Flight mode is linked with restlessness and anxiety. Individuals may have a sense of needing to get up and go-pacing, changing environments constantly, or avoiding tasks that seem too overwhelming. Someone with a flight response might have the desire to change jobs constantly, relocate constantly, or become reclusive in order to avoid perceived dangers.

3. Freeze

The freeze response occurs when the nervous system perceives a threat as too overwhelming to fight or flee. Rather than taking action, individuals shut down, feeling numb, disconnected, or paralyzed by fear.

Unlike fight or flight, which involve heightened activation, freeze mode slows down physiological functions. A person experiencing freeze mode may feel physically unable to move, struggle to make decisions, or find themselves dissociating from their emotions. This can manifest in situations such as public speaking anxiety, where someone might "blank out" or feel stuck in the moment.

What Happens in the Body During A Stressful Event?

When faced with a stressor, the autonomic nervous system (ANS) activates, triggering physiological changes, including:

• Increased heart rate and breathing: The body pumps more oxygen to muscles and the brain in case action is needed.
• Muscle tension: The body prepares for movement, sometimes causing trembling or stiffness.
• Dilated pupils: Vision sharpens to detect potential threats.
• Dry mouth: Saliva production decreases as the body redirects energy to essential functions.
• Changes in skin tone: Blood flow is directed to vital organs, sometimes making the skin appear pale or flushed.

For those experiencing the freeze response, the body undergoes a different reaction, often reducing heart rate and causing physical immobility rather than heightened activation.

Strategies for Coping and Managing the Stress Response

While the stress response is necessary for survival, frequent activation due to daily stressors can take a toll on health. Recognizing your default response—whether fight, flight, or freeze—can help in developing effective coping mechanisms.

1. Moving to a Safe Space

If possible, changing your environment can help signal to your brain that the threat has passed. Stepping outside for fresh air, finding a quiet place, or distancing yourself from overwhelming stimuli can help regulate emotions.

2. Practicing Controlled Breathing

Deep, slow breathing can be used to counteract the stress response by engaging the parasympathetic nervous system, which promotes relaxation. Techniques such as diaphragmatic breathing or the 4-7-8 method (inhale for four seconds, hold for seven, exhale for eight) can be particularly effective in calming the body.

3. Engaging in Physical Activity

This helps release pent-up energy and aids in the endorphin cascade, natural boosters for our mood.

4. Seeking Social Support

Relieving oneself from stress can come in many ways, but sharing it with trusted friends, a family member, or a good therapist will sure give that psychological boost of hope. Social support is an especially effective way of cushioning people against the stressors that they are subjected to in chronic forms.

When to Seek Professional Help

While occasional stress is normal, chronic activation of the fight, flight, or freeze response can indicate underlying mental health concerns, such as anxiety disorders or post-traumatic stress disorder (PTSD). If stress is affecting daily life—leading to sleep disturbances, difficulty concentrating, or persistent feelings of fear—it may be time to consult a mental health professional.

A Parliamentary Standing Committee on Health and Family Welfare has raised serious concerns about growing doctor burnout, especially among junior and senior resident doctors, and warned that it is now affecting both doctor well-being and patient safety. Noting that overworked doctors are a risk for patient safety, the panel said that fatigue-driven errors and burnout could compromise care.

To tackle this, the committee recommended that the government introduce and strictly enforce a formal “Clinical Duty Hours Regulation” policy. This should mandate fixed rest periods and monitored duty rosters, with oversight mechanisms to prevent violations, stated the panel in its 172nd report presented before the Parliament.

The recommendation comes amid growing concern over long, unregulated shifts in teaching hospitals, where residents often work extended hours with limited rest.

The panel warned that such conditions not only increase the likelihood of clinical mistakes but also contribute to burnout and mental health stress among young doctors.

What The Parliamentary Panel Said

The Panel noted that due to persistent human resource shortages, the working hours of junior and senior residents doctors often stretch from 24 to 36 hours. This increases risk of clinical errors and burnout, thereby compromising patient safety. Thus it recommended a mandatory working-hour regulatory framework:

• to minimize fatigue-induced clinical errors
• safeguard their mental and physical well-being,
• improving patient safety.

However, it noted the contractual engagement must not substitute regular appointments, as excessive reliance on contractual staff may dilute institutional accountability and continuity.

Instead, the panel has recommended adopting a "Total Support model for medical professionals" to attract and retain qualified doctors and specialists in the public health system.

Also read:India Must Integrate Technology To Build Preventive, Holistic Healthcare: Experts

What Is Clinical Duty Hours Regulation policy

The policy calls to:

• Ensure mandatory rest periods, monitored rosters.
• Ensure the presence of senior faculty in wards and in operating theatres during peak hours
• Align faculty schedules with clinical demand
• Offer Structured mentorship
• Protected teaching time for trainees to gain supervised clinical experience
• Improved working conditions, including accommodation, transportation, and administrative support, on par with the facilities afforded to senior civil servants,
• Transparent career progression with time-bound promotions.
• Integrate Yoga and the Indian Knowledge System (IKS) within the workforce to address depression and psychiatric issues.

Also read: Doctors Share Preventable Risk Factors That Can Land You in the Emergency Ward

What Is Burnout?

Burnout is distinct from depression, which influences every aspect of life and often involves persistent thoughts of hopelessness or worthlessness. Burnout typically involves limited manifestations to the work environment, although its impact can resonate into other areas.

Symptoms of Burnout

1. Exhaustion: Prolonged mental and physical depletion of your energy levels.

2. Depersonalization: Cynicism and lack of concern creep into relationships and communication.

3 Reduced Personal Achievement: Your work loses worth, and you may feel you are not up to standards, giving in to frustration and reduced originality.

These signs frequently coincide with physical signs (headaches, muscle pain, sleeplessness), emotional signs (self-doubt, loneliness, unhappiness), and behavioral signs (social withdrawal, outbursts of anger, abandonment of obligations).

Continuing the legacy of football legend Joe Thompson, his wife Chantelle revealed she is pregnant with his baby after IVF treatment using frozen embryos.

Joe Thompson died in 2025 after developing cancer for a third time - beating the illness twice.

But after the former Manchester United star was diagnosed with Hodgkin Lymphoma for a third time, which had spread to his lungs, he died aged 36.

"It just means absolutely everything. I know it's never going to replace Joe obviously. Joe's Joe. But to be able to bring his baby into the world again is beautiful," Chantelle said.

She said Joe had two visions of their family with a baby boy before he died, and he even gave her the name for the baby boy he predicted, and she got pregnant on her first attempt of IVF after he had died.

How Egg Freezing Works

Egg freezing, also known as oocyte cryopreservation, is an option that has gained significant traction in recent years. It offers women the ability to pause their biological clock and preserve the possibility of having children in the future.

Egg freezing takes a woman's unfertilized eggs from her ovaries and stores them at sub-zero temperatures to be utilized later. It is made to enable women to keep their fertility intact, especially if they are not yet ready to have a baby.

Dr. Pavithra M, Obstetrician, Gynecologist, and Infertility Specialist, told HealthandMe that the workup begins with hormone workup and evaluation of various parameters, such as age, body mass index (BMI), and ovarian reserve.

"On the second day of the menstrual cycle, baseline ultrasound scanning is performed to assess the number of follicles; thereafter, various tests of blood are conducted to assess hormone levels. If a woman's parameters are all normal, then she is administered hormonal injections for about 10-12 days."

It causes ovarian hyperstimulation and multiple mature eggs, monitored through ultrasound scans. A trigger shot is administered once the follicles have reached optimal size to help with final egg maturation. It takes 34-35 hours from the trigger shot, wherein eggs are retrieved by minimally invasive procedures under general anesthesia.

"Using a transvaginal ultrasound probe with a needle, each follicle is punctured, and the follicular fluid is aspirated. The retrieved eggs are then screened for quality before undergoing vitrification—a rapid freezing technique that minimizes ice crystal formation and cellular damage," Dr. Pavithra added. The eggs are then stored in liquid nitrogen tanks for long-term preservation.

While egg freezing is possible at various stages of life, experts recommend doing it at an optimal age -- in the late 20s or early 30s when the eggs are of higher quality-- for better outcomes.

Annabelle Gurwitch, an American author, actress, and television host, has opened up about her lung cancer diagnosis in her new memoir.

In her sixth book, ‘The End of My Life Is Killing Me’, Annabelle Gurwitch offers a satirical take on her journey with stage 4 lung cancer. The best-selling author found out about her cancer status in 2020, when she went for a COVID-19 test.

In the book, Annabelle Gurwitch writes about her life as a "cancer slacker", her divorce, treatment with a targeted therapy that turns off the gene that has gone rogue, radiation, and chemotherapy, all with a humorous take.

Lung Cancer: A Stealthy Disease, Says Annabelle Gurwitch

Notably, the American actress had no symptoms and was not a smoker. She went to get her “persistent little cough” tested for COVID, when a doctor told her that there was something suspicious on her lungs.

Soon after, an X-ray and a biopsy confirmed her diagnosis of stage 4 cancer.

Annabelle Gurwitch called lung cancer a “stealthy disease" as, other than her little cough, she exercised every day and felt like she was in really good health.

“You know, you can be asymptomatic with Stage 4 lung cancer because lung cancer is a really stealthy disease, and this is why it's such a big killer, still the No. 1 cause of cancer deaths, because some lung cancers, like the one I have, are not recognized by the immune system," Annabelle Gurwitch told NPR.

"So my body didn't know that it was - anything was happening, which is, I mean, I was going to regular doctor's appointments. And this is why it's often diagnosed at a late stage, and such a big killer because it's not diagnosed at an earlier stage,” she added.

Also read: Early-Stage Lung Cancer Surgery Safe, Effective Even After 80, Reveals Lancet Study

Can Non-Smokers Get Lung Cancer?

Contrary to long-held assumptions, a significant proportion of lung cancer cases now occur in people with no history of smoking. The American Cancer Society reports that approximately 10-20 percent of lung cancers in the U.S are found in non-smokers, often attributed to genetic mutations like EGFR, environmental exposures, or radon gas.

These cases are more common in women, younger adults, and individuals of East Asian descent, but they can affect anyone.

Also read: New AIIMS Study To Probe How PM2.5 Is Surging Lung Cancer Risk In India

Early Signs and Symptoms to Look Out For

Lung cancer symptoms can mimic less serious conditions, which is why they’re often dismissed or misdiagnosed. If you experience the following symptoms persistently, don’t ignore them—regardless of your age or smoking history:

• Chest pain or discomfort
• Unexplained shortness of breath
• Persistent cough or wheezing
• Shoulder, back, or rib pain
• Fatigue or sudden weight loss
• Blood in sputum (though not always present).