Mold Exposure (Credit: Canva)
Mold is a type of fungus that has been found on the surface of the earth for millions of years. They can get inside your home through open doors, windows, and air conditioning systems. Inhaling mold spores or coming into contact with mold can have severe adverse effects on your health. Beyond physical symptoms like headache and allergic symptoms, it can have a significant impact on the brain and nervous system. Symptoms may vary, from mild headaches to more severe issues like memory loss or difficulty walking. While it can affect anybody, certain groups like children, the elderly, pregnant women, and those with weakened immune systems are particularly vulnerable to these effects.
How can mold impact your neurological health?
Mold, such as Cladophialophora bantiana, can cause infections in the brain and spinal cord, leading to serious conditions like central nervous system (CNS) infections. While such infections are rare, they can be life-threatening.
Mycotoxins are toxic chemicals produced by certain mold types. These toxins can be released into the air when mold grows indoors, and breathing them in can have direct harmful effects on brain function. Studies indicate that mycotoxins may interfere with the nervous system’s communication pathways, leading to cognitive issues such as memory problems and mood swings.
In fact, long exposure to mold can lead to a variety of neurological symptoms, which can differ depending on an individual’s health and the severity of the mold exposure. Some of them are:
Headaches are one of the most frequent symptoms of mold exposure. While most of the time, these headaches are described as dull, constant, or pressure-like, they can sometimes mimic migraines, accompanied by nausea or sensitivity to light and sound.
Exposure to molds can also trigger seizures. Mold produces toxic substances like mycotoxins that may disrupt the brain’s electrical activity, leading to seizure episodes.
Mold exposure can cause brain fog, which results in concentration, memory, and mental clarity. Studies suggest that mycotoxins can disrupt normal brain function, making it challenging to process information and think clearly.
Exposure to this fungus can also lead to emotional problems. People with this kind of exposure have complained of anxiety, depression, irritability, and sudden mood swings. This could be due to mold toxins interfering with brain chemicals responsible for regulating emotions.
Mold exposure may trigger inflammation, leading to muscle and joint pain. In case of prolonged exposure, it could lead to the development or worsening of fibromyalgia or complex regional pain syndrome (CRPS).
In some cases, mold exposure may lead to tremors, difficulty walking, or problems with muscle coordination. These issues may be linked to mycotoxins affecting the brain or nervous system.
Mold exposure can impact the brain areas responsible for movement and balance, making it harder to stand, walk, or perform fine motor tasks. Individuals may feel unsteady or experience difficulty using devices like phones or computers.
Delirium is a condition wherein a person experiences confusion or disorientation. An abnormal immune response to mold could contribute to this condition. Delirium can make it difficult for individuals to think clearly or understand their surroundings.
Credit: Canva
Do you know that congenital hypothyroidism, a rare disability, affects about 1 in 2,500–3,000 newborns globally, but in India, the incidence is higher -- approximately 1 in 1,000 births.
India records nearly 26 million births annually, with an estimated 10,000 babies born each year with Congenital Hypothyroidism.
This means 27 babies are born every day in India, with the condition that more than one is born every hour. Early treatment within the first 2 weeks of life can ensure normal brain development, while delayed treatment can reduce IQ by 30–50 points.
Congenital Hypothyroidism (CH) is a condition present at birth in which a baby’s thyroid gland does not produce enough thyroid hormone.
The thyroid is a small gland located in the neck. It produces a hormone called thyroxine (T4), which is essential for brain development, growth, and overall body metabolism. The thyroid hormone is especially important in the first few weeks of life.
The thyroid hormone helps in:
If a baby does not receive enough thyroid hormones soon after birth, it can lead to permanent intellectual disability and growth problems.
The good news is that congenital hypothyroidism is easily detectable and completely treatable if identified early.
What Causes Congenital Hypothyroidism? What Are The Symptoms?
Congenital Hypothyroidism may occur because:
One of the biggest challenges with Congenital Hypothyroidism is that most babies look completely normal at birth.
However, over time, some signs may appear:
How Is Congenital Hypothyroidism Detected?
1. Newborn Screening Test (Heel-Prick Test)
2. Confirmatory Blood Tests
If the screening test is abnormal, the doctor will order:
3. Thyroid Scan
In some cases, imaging tests are needed. The ultrasound of the neck (less accurate) and Nuclear Medicine Thyroid scan (more accurate) may be done to check whether the gland is absent, small, or misplaced. However, treatment should not be delayed while waiting for imaging.
When Should Treatment Start?
Treatment should begin as early as possible -- ideally within the first 14 days of life. Starting treatment within the first two weeks allows normal brain development.
Delaying treatment increases the risk of permanent intellectual disability.
Doctors will monitor:
Initially, blood tests are done every 2–4 weeks, then less frequently as the child grows. Proper follow-up ensures the dose remains correct. Some babies may need treatment for life.
In certain cases, doctors may reassess thyroid function after 3 years of age to see whether the condition is temporary or permanent. Most children who receive early and proper treatment grow up with completely normal intelligence and physical development.
Can Congenital Hypothyroidism Be Prevented? Why Early Screening Is So Important
Most cases cannot be prevented. However:
A baby with Congenital Hypothyroidism may look perfectly healthy. Without screening, diagnosis may be delayed until symptoms appear—by then, brain development may already be affected.
With early testing the diagnosis is simple; treatment is affordable; and outcome is excellent. But without testing:
Congenital Hypothyroidism is one of the most preventable causes of intellectual disability in children. A small heel-prick test in the first few days of life can protect your baby’s brain forever.
If you are expecting a baby or have a newborn, speak to your doctor about newborn thyroid screening.
Early diagnosis. Simple treatment. Normal life.
Credit: Health Ministry
Prime Minister Narendra Modi today launched the nationwide Human Papillomavirus (HPV) vaccination campaign for girls aged 14 years from Rajasthan's Ajmer.
The initiative marks a decisive step towards eliminating cervical cancer through timely HPV vaccination. Cervical cancer remains the second most common cancer among women in India. Nearly 80,000 new cases and over 42,000 deaths are reported annually in the country.
"Today, I have had the opportunity to launch the HPV vaccine campaign from Ajmer. This campaign is an important step towards empowering women and daughters of this country,” PM Modi said.
“For us, this was a sensitive issue tied to the insult of our sisters and daughters, one that made them ill. That is why we resolved it at a crucial turning point in their mission,” he added.
The World Health Organization has also lauded India's mission to launch the HPV vaccine and prevent the risk of cervical cancer.
“We are leaving no stone unturned to ensure that the daughters of the country are healthy and prosperous. The objective of this initiative is the prevention of cervical cancer," the Prime Minister, earlier wrote in a post on social media platform X.
The nationwide program, based on expert recommendations of the National Technical Advisory Group on Immunization (NTAGI), will target girls aged 14 years.
At 14, the HPV vaccine offers maximum preventive benefit, well before potential exposure to the virus.
"By prioritizing prevention at the right age, the program is expected to provide lifelong protection and significantly reduce the future burden of cervical cancer in the country," the government said.
“The HPV vaccine works best at 9-14 years, before exposure, and when the immune response is strongest. Studies show effectiveness is highest in younger age groups and decreases with age,” Dr. Parmod Kumar, Associate Professor in Medical Oncology, AIIMS Jodhpur, shared on X.
Vaccination under the national program will be voluntary and free of cost.
The HPV vaccination will be conducted exclusively at designated government health facilities, including Ayushman Arogya Mandirs (Primary Health Centers), Community Health Centers, Sub-District and District Hospitals, and Government Medical Colleges.
Despite being preventable, cervical cancer continues to claim the life of a woman every two minutes globally, and the WHO South-East Asia Region bears nearly one-quarter of the global burden.
Dr. Catharina Boehme, Officer-in-Charge, WHO South-East Asia, stated that the introduction of HPV vaccination at a national scale in India "will have a far-reaching impact". It will accelerate progress not only for the country, but for the region and the world, she said.
“This landmark step, led at the highest level of government, reflects India’s strong commitment to protecting adolescent girls from cervical cancer," said Dr. Boehme.
With today’s milestone, nine of the 10 countries in the Region now include HPV vaccination in their national immunization programs.
The WHO global targets for 2030 include vaccinating 90 percent of girls by age 15, screening 70 percent of women by ages 35 and 45, and ensuring 90 percent of women with pre-cancer and invasive cancer receive appropriate treatment.
Credits: Canva
As we grow older, it is almost expected that memory will fade. Names slip. Dates blur. Thoughts take longer to form. Inside the aging brain, proteins can misfold and clump together, damaging cells and gradually eroding cognition. But not everyone follows this script.
Some people reach their 80s with memory and mental sharpness that rival those decades younger. Scientists call them “super-agers.” Now, new research published in Nature offers a possible explanation for why some brains hold up so remarkably well.
At the heart of the findings lies one of neuroscience’s most contested questions: can adult human brains grow new neurons?
Read: A Longevity Expert Who Studies 'Super Agers' Eats All THIS In A Day
For years, scientists have debated whether neurogenesis, the birth of new neurons, continues into adulthood. While it is well established in babies and young children, and in many animal species, evidence in adult humans has been mixed.
This new study adds weight to the idea that it does continue, even into advanced age.
Researchers examined brain tissue donated after death from several groups: younger adults with normal cognition, older adults with typical memory for their age, people with mild cognitive impairment, individuals with Alzheimer’s disease, and super-agers over 80 whose memory functioned like someone about 30 years younger.
They focused on the hippocampus, the brain’s memory hub and a region long suspected to be a birthplace for new neurons.
To detect neurogenesis, scientists looked for three types of cells: neural stem cells, neuroblasts, and immature neurons. In simple terms, stem cells are like infants, neuroblasts are adolescents, and immature neurons are on the brink of adulthood.
“We identified genetic markers for three key types of cells,” the researchers explained, tracing the pathway from stem cell to developing neuron.
All groups showed signs of these cell types. The difference lay in the numbers.
Super-agers had roughly twice as many new neurons as older adults with typical memory, and about two and a half times more than those with Alzheimer’s disease. In fact, their hippocampi contained even more immature neurons than the brains of younger adults.
“This paper shows biological proof that the aging brain is plastic,” Tamar Gefen told The New York Times. She added that this adaptability appears to persist “even into a person’s 80s.”
The immature neurons in super-agers also carried distinctive genetic and epigenetic signatures. According to Gefen, as quoted by The New York Times, “Super-aging happens not only because there’s more of these young cells, but because there is a type of genetic programming” that allows them to survive and resist age-related decline.
In other words, it is not just about quantity. It may also be about resilience.
The Alzheimer’s findings were equally intriguing.
People with Alzheimer’s actually had more neural stem cells than other older adults. But they had far fewer neuroblasts and immature neurons. This suggests that while the starting material was present, the developmental process stalled.
One interpretation is that neurogenesis becomes disrupted in Alzheimer’s. Stem cells may remain dormant, unable to mature into functioning neurons.
“If that’s true, that’s really opened up a new direction for the field,” Hongjun Song told The New York Times, suggesting that reactivating these dormant cells could one day become a therapeutic strategy.
It is an exciting possibility. Instead of only trying to prevent damage, scientists might be able to encourage regeneration.
The neurogenesis debate is far from settled.
Some researchers argue that methodological differences have led to conflicting conclusions over the years. Shawn Sorrells, who studies neurogenesis, told The New York Times that mapping how the hippocampus changes in people who age differently is “fantastically interesting and important,” but he cautioned that the findings should be validated using additional techniques.
Skepticism remains because detecting new neurons in adult human brains is technically difficult. Results often hinge on the markers and imaging tools used.
Even if this study does not end the debate, it opens new doors. If certain people naturally maintain robust neurogenesis into their 80s, researchers want to understand why. Is it genetics? Lifestyle? A combination of both?
Scientists are now exploring whether the special properties seen in super-agers’ immature neurons can be replicated or supported through medication or other interventions.
The bigger takeaway is hopeful. Aging does not necessarily mean inevitable cognitive collapse. The brain may retain more capacity for renewal than once believed.
If neurogenesis truly persists across the lifespan, the story of brain aging may need rewriting. Instead of focusing only on decline, researchers may increasingly look toward regeneration and resilience.
And for anyone worried about forgetting where they left their keys, that possibility feels quietly revolutionary.
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