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We've all been there, you use the toilet, try to stand up, and suddenly your legs go numb. That odd pins-and-needles feeling can be surprising and uncomfortable. Though it might feel like a small inconvenience, it does have a scientific explanation. The numbness, also called transient paresthesia, happens when pressure blocks blood flow or presses on nerves in your lower extremities. It is normally harmless, but frequent occurrences can be signs of underlying health issues or poor toilet habits that must be addressed.
That weird numbness you experience after going to the bathroom is typically just a temporary annoyance, most often due to bad posture, straining, or sitting for an extended period. But if the numbness continues or gets worse, it is important to get medical guidance to make sure there are no underlying health issues. We discovered the top three reasons that could be responsible for this tingling and how can you avoid it? Let's dissect.
Struggling to push during a bowel movement can put excessive pressure on your abdomen and spine. This increased pressure can shift spinal discs, pressing against nerves that extend into your legs and feet. The result? A temporary loss of sensation, tingling, or weakness in your lower limbs.
Straining usually results from constipation, which in turn can be caused by a low-fiber diet, dehydration, or inactivity. If you notice that you're straining frequently, perhaps it's time to change your eating and drinking habits to help move your bowels more easily.
The way you sit on the toilet can also be a cause of that numbness in your legs. Most people are prone to hunching over when they are using their phones, reading, or just focusing too intensely. But this position can compress nerves and blood vessels in your pelvis, causing tingling or numbness.
When you sit slumped forward, you cut off blood supply to the lower half of your body, compressing nerves that travel from your pelvis to your toes. That's why the numbness will often radiate past your thighs and into your toes.
The more time you spend sitting on the toilet, the higher your chance of getting numb legs. Protracted sitting continually puts pressure on the nerves within your lower limbs, slowing blood flow and leaving you with the familiar pins-and-needles feeling.
If you habitually stay on the toilet for a long time, either from digestive problems or distractions such as browsing your phone, you may find that there is more numbness over the course of time. If constipation is leaving you on the toilet longer than normal, diet changes can calm your system.
Although periodic tingling is not a health issue, recurring numbness is a problem that needs to be addressed. Below are some professional-recommended ways of preventing it:
Being seated with your knees higher than your hips can make all the difference. Sitting this way enables your colon to unwind, facilitating smooth bowel movements while minimizing pressure on the lower parts of your body.
Don't slouch, as this squishes nerves and blood vessels, making numbness more likely. If necessary, lean your back against the toilet tank or wall to keep your posture good.
Specialists recommend five to ten minutes of toilet time per visit. If you are straining, stand up, walk around, and try later. Forcing the bowel movement can cause more damage than benefit, putting greater pressure on your spine and worsening numbness.
If constipation is a chronic problem, being hydrated and consuming fiber foods such as fruits, vegetables, and whole grains can get your digestive system back in working order.
Raising your feet using a toilet stool may position your body for a more natural and strain-free bowel movement. A squatting position keeps the rectal canal open, minimizing the need to push and reducing the risk of leg numbness.
Hard toilet seats can restrict circulation in your lower body, increasing the risk of numbness. A cushioned or padded toilet seat can provide better support, improving blood flow to the legs and feet while reducing pressure on the pelvis.
While it's normal to have some numbness in your legs from time to time when sitting on the toilet, ongoing tingling or numbness in your lower extremities may be a symptom of an underlying medical condition. If you find yourself experiencing:
It's best to see a healthcare expert to exclude conditions such as nerve compression, circulatory disorder, or spinal condition.
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Dehydration is a serious concern for people fasting during the month-long Ramadan period, and can severely impact kidney and prostate health. Experts suggested that avoiding excess salt and caffeine can help.
While Ramadan fasting is generally safe for people with early-stage chronic kidney disease (CKD), maintaining adequate hydration between iftar and sehri -- the two important meals each day for faithful observing the fasting -- is of significant importance.
Dehydration can lead to acute kidney injury and electrolyte imbalances for individuals with advanced CKD. As prolonged fasting hours -- more than 12 hours a day -- urine becomes concentrated, increasing the risk for kidney stones and Urinary Tract infections (UTIs).
For men with prostate problems, fasting during Ramadan can pose challenges, such as Benign Prostatic Hyperplasia (BPH) or an enlarged prostate, primarily due to dehydration.
“As a practicing urologist and kidney transplant surgeon in India, I often notice a rise in kidney stone pain and urinary infections during Ramzan. When patients fast for long hours -- especially in our warm climate -- urine becomes highly concentrated. That increases the risk of stones and UTIs. Men with prostate enlargement sometimes report worsening urinary flow because they consciously reduce fluid intake,” Dr. Pankaj Panwar, Additional Director, Urology, Fortis Escorts Okhla, New Delhi, told HealthandMe.
The doctor advised people “to hydrate strategically between Iftar and Sehri, avoid excess salt and caffeine”.
Consuming high-sodium foods such as processed meats, pickles, salty snacks, and fast food during iftar or sehri can increase thirst and dehydration.
High salt intake forces the body to pull water from cells to dilute the sodium, leading to severe thirst. It can also lead to bloating.
Similarly, caffeine in coffee, tea, chocolate, and energy drinks can be diuretic and cause the body to lose fluids and salts through increased urination. Particularly, drinking coffee or tea at sehri -- the pre-dawn meal -- can lead to faster dehydration during the day.
Caffeine consumption, especially late in the evening, can also interfere with sleep, making it harder to wake up for sehri.
“Ramzan is a sacred month of fasting, but prolonged abstinence from water, especially in hot climates, can increase dehydration risk. Concentrated urine puts stress on the kidneys and may worsen kidney stones or trigger urinary tract infections,” Dr. Mangesh Patil, Urologist at Saifee Hospital, Mumbai, told HealthandMe.
Dehydration during Ramadan fasting can lead to symptoms like headaches, extreme thirst, fatigue, and dizziness. But in case of severe dizziness, fever, confusion, or blurred vision, the experts warned of immediate medical help.
“Do not ignore warning signs like flank pain, fever, or difficulty passing urine. A little planning can prevent an emergency hospital visit,” Panwar said.
Patil said warning signs include severe flank pain, burning urination, fever, vomiting, blood in urine, or reduced urine output. Men with Benign Prostatic Hyperplasia may notice worsening urinary symptoms.
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Colon (colorectal) cancer begins when small growths called polyps form on the inner lining of the colon or rectum. Over time, changes in the DNA of these cells can cause the polyps to become cancerous.
As abnormal cells multiply, they replace healthy cells and eventually form a mass known as a tumor. This process develops slowly, often taking up to ten years for a precancerous polyp to turn into cancer and begin showing symptoms.
Colon cancer poses serious health risks because cancerous cells can invade healthy tissues. Over time, they may break away and spread to other parts of the body, making detection more difficult since the symptoms can resemble other conditions.
Colon cancer can be difficult to detect because it often develops without obvious symptoms. However, doctors emphasize that the number one warning sign is rectal bleeding or blood in your stool.
"Colon cancer can be hard to diagnose because it can develop asymptomatically,” said Dr. John Nathanson, a gastroenterologist at New York-Presbyterian Allen Hospital.
Dr. Pratima Dibba adds that this symptom should not be misdiagnosed as hemorrhoids, infection, or constipation, since early signs of colon cancer can look similar.
She urges patients to get checked promptly to rule out serious conditions.
Research from the Cleveland Clinic also shows that blood in stool can originate anywhere in the gastrointestinal tract, including the colon.
Detecting colon cancer early is critical, as survival rates can be as high as 90 percent when caught in its initial stages.
Persistent changes in bowel habits (diarrhea, constipation, or narrowing of stool). Other signs include:
Colorectal cancer (CRC) is a major health concern worldwide. In India, it is the fourth most common cancer among both men and women. In 2022, there were 64,863 new cases and 38,367 deaths.
Projections suggest that incidence will continue to rise by 2026, reflecting both lifestyle changes and improved detection.
Compared to developed countries, survival rates in India remain lower, largely due to late-stage diagnosis and limited access to screening programs.
The American Cancer Society notes that colorectal cancer is a cancer that starts in the colon or the rectum. Colorectal cancer impacts around 1.9 million people every year, noted the World Health Organization (WHO) as per its 2022 data.
Some of the risk factors include risk factors involve being over the age 50, family history, certain genetic syndromes (like Lynch syndrome), inflammatory bowel diseases, and lifestyle factors (diet high in red meat, alcohol, smoking, inactivity).
The most effective way to prevent colorectal cancer is through annual colonoscopies, screening and stool tests.
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Ever wondered how your body generates antibodies in the face of a virus attack? A new study by French researchers showed that our age, biological sex, and human genetic factors can determine our immunity levels.
The human body, when exposed to a virus, defends itself by producing molecules called antibodies. Their main function is to identify pathogens and kill them.
Scientists from the Institut Pasteur, the CNRS, and the Collège de France noted that these factors not only boost the quantity of antibodies produced in the body but also determine the specific viral regions to target.
The February 2026 study, published in the journal Nature Immunology, can pave the way for the development of personalized treatments, especially for individuals who are most vulnerable to infection.
"This study provides a detailed, integrated view of how age, sex, and human genetics shape the antibody response," said Lluis Quintana-Murci, Head of the Human Evolutionary Genetics laboratory at the Institut Pasteur.
"It shows that these factors even determine which specific regions of a given virus are targeted by antibodies, with important implications for vaccine and therapeutic design," Quintana-Murci added.
How Age And Sex Influence Immunity
The findings revealed that individuals produce antibodies that target different parts of the virus when attacked by the same virus. Age was identified as the dominant factor influencing antibody production. The team noted that more than half of the antibody repertoire varies depending on age.
Further, some antibodies were found to increase with age, while others decreased. This was seen particularly in the case of influenza H1N1 and H3N2 viruses.
In young adults, the antibodies mainly targeted a part of the viral surface protein known as hemagglutinin (HA), which evolves rapidly. In older individuals, it focused on a more stable region of the same protein known as the stalk domain.
Women were also found to produce more antibodies against HA. On the other hand, men tended to target other viral proteins (NP and M1), despite comparable vaccination rates between the two sexes.
How Human Genetics Shape Antibody Production
The team identified mutations in genomic regions known to encode the immunoglobulin repertoire. These variants determine which genes are used to produce antibodies.
Using an African cohort, the study revealed population disparities in terms of the molecular targets of their antibody repertoires.
In the case of Epstein-Barr virus (EBV), antibodies were found to recognize different viral proteins depending on the geographical and epidemiological context.
This difference can be explained by the level of exposure -- Africans are more exposed to a particular strain of EBV in which the protein EBNA-4 is the primary antibody target.
How Was The Study Conducted?
The research is based on data from the Milieu Intérieur cohort, launched 15 years ago to study variations in the immune response in 1,000 healthy individuals.
Using an innovative sequencing technology, the scientists analyzed blood plasma samples to measure antibody responses against more than 90,000 fragments of viral proteins, covering a large number of viruses responsible for infections such as influenza, respiratory infections, gastroenteritis, and herpesvirus infections.
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