We've all been there, you use the toilet, try to stand up, and suddenly your legs go numb. That odd pins-and-needles feeling can be surprising and uncomfortable. Though it might feel like a small inconvenience, it does have a scientific explanation. The numbness, also called transient paresthesia, happens when pressure blocks blood flow or presses on nerves in your lower extremities. It is normally harmless, but frequent occurrences can be signs of underlying health issues or poor toilet habits that must be addressed.

That weird numbness you experience after going to the bathroom is typically just a temporary annoyance, most often due to bad posture, straining, or sitting for an extended period. But if the numbness continues or gets worse, it is important to get medical guidance to make sure there are no underlying health issues. We discovered the top three reasons that could be responsible for this tingling and how can you avoid it? Let's dissect.

3 Reasons Your Legs Go Numb on the Toilet

1. You’re Straining Too Much

Struggling to push during a bowel movement can put excessive pressure on your abdomen and spine. This increased pressure can shift spinal discs, pressing against nerves that extend into your legs and feet. The result? A temporary loss of sensation, tingling, or weakness in your lower limbs.

Straining usually results from constipation, which in turn can be caused by a low-fiber diet, dehydration, or inactivity. If you notice that you're straining frequently, perhaps it's time to change your eating and drinking habits to help move your bowels more easily.

2. Inadequate Sitting Posture

The way you sit on the toilet can also be a cause of that numbness in your legs. Most people are prone to hunching over when they are using their phones, reading, or just focusing too intensely. But this position can compress nerves and blood vessels in your pelvis, causing tingling or numbness.

When you sit slumped forward, you cut off blood supply to the lower half of your body, compressing nerves that travel from your pelvis to your toes. That's why the numbness will often radiate past your thighs and into your toes.

3. Sitting for Too Long

The more time you spend sitting on the toilet, the higher your chance of getting numb legs. Protracted sitting continually puts pressure on the nerves within your lower limbs, slowing blood flow and leaving you with the familiar pins-and-needles feeling.

If you habitually stay on the toilet for a long time, either from digestive problems or distractions such as browsing your phone, you may find that there is more numbness over the course of time. If constipation is leaving you on the toilet longer than normal, diet changes can calm your system.

How to Stop Your Legs from Falling Asleep on the Toilet

Although periodic tingling is not a health issue, recurring numbness is a problem that needs to be addressed. Below are some professional-recommended ways of preventing it:

1. Proper Posture

Being seated with your knees higher than your hips can make all the difference. Sitting this way enables your colon to unwind, facilitating smooth bowel movements while minimizing pressure on the lower parts of your body.

Don't slouch, as this squishes nerves and blood vessels, making numbness more likely. If necessary, lean your back against the toilet tank or wall to keep your posture good.

2. Don't Spend Too Long on the Toilet

Specialists recommend five to ten minutes of toilet time per visit. If you are straining, stand up, walk around, and try later. Forcing the bowel movement can cause more damage than benefit, putting greater pressure on your spine and worsening numbness.

If constipation is a chronic problem, being hydrated and consuming fiber foods such as fruits, vegetables, and whole grains can get your digestive system back in working order.

3. Use a Toilet Stool

Raising your feet using a toilet stool may position your body for a more natural and strain-free bowel movement. A squatting position keeps the rectal canal open, minimizing the need to push and reducing the risk of leg numbness.

4. Try a Padded Toilet Seat

Hard toilet seats can restrict circulation in your lower body, increasing the risk of numbness. A cushioned or padded toilet seat can provide better support, improving blood flow to the legs and feet while reducing pressure on the pelvis.

When to Seek Medical Advice

While it's normal to have some numbness in your legs from time to time when sitting on the toilet, ongoing tingling or numbness in your lower extremities may be a symptom of an underlying medical condition. If you find yourself experiencing:

• Bathroom-use-independent frequent numbness
• Muscle weakness
• Pain or discomfort in legs or lower back
• Loss of bladder or bowel control

It's best to see a healthcare expert to exclude conditions such as nerve compression, circulatory disorder, or spinal condition.

A daily pill for weight loss can help people reduce their body weight by as much as a fifth, according to a large clinical trial that researchers say could reshape obesity treatment and make therapies more accessible. The drug, called orforglipron and manufactured by Eli Lilly, works by targeting the same GLP-1 receptors as popular injectable drugs such as Mounjaro and Wegovy.

The study, published in the New England Journal of Medicine and presented at the European Association for the Study of Diabetes meeting in Vienna, followed 3,127 adults with obesity but no diabetes across multiple countries. After 72 weeks, one in five participants taking the pill lost 20% or more of their body weight, a result health experts are calling a potential breakthrough.

Also Read: Eli Lilly Sends Weight-Loss Pill For Approval: Is Oral GLP-1 As Effective As The Injections?

How Orforglipron Works

Orforglipron belongs to the class of GLP-1 receptor agonists, medications that lower blood sugar, slow digestion, and suppress appetite. These drugs mimic hormones naturally released in the gut, signaling to the brain a feeling of fullness.

While injectable GLP-1 drugs have been hailed as transformative, a pill version is seen as a “holy grail” because it is easier to store, distribute, and take, reducing the barriers to treatment. Pills are also expected to be cheaper than weekly injections, widening access for millions.

Results of the 72-Week Trial

Participants were randomly assigned to receive different daily doses of orforglipron, ranging from 6 mg to 36 mg, or a placebo. All had a body mass index (BMI) of 30 or higher.

Average weight loss:

• 7.5% with the lowest dose (6 mg)
• 11.2% with the highest dose (36 mg)

Proportion of patients with major weight reduction on 36 mg:

• 54.6% lost at least 10% of body weight
• 36% lost at least 15%
• 18.4% lost at least 20%

Beyond weight reduction, the study noted improvements in blood pressure, waist circumference, and cholesterol levels. Side effects were mostly gastrointestinal, such as nausea and diarrhea, and were generally mild to moderate.

Lead researcher Dr. Sean Wharton of McMaster University said:

“This could mean an expansion of obesity interventions to groups who are currently excluded due to the cost of and lack of access to injectable medications.”

Why the Pill Matters

The rise of GLP-1 drugs has already begun to reshape obesity and diabetes treatment. But injections create added costs and logistical hurdles for health services. A pill that achieves similar results could be a turning point for how obesity is managed globally.

Experts stress, however, that while the pill’s results are promising, it is not yet approved by the FDA or other global regulators. Eli Lilly has said it expects strong demand once it launches, potentially within the next year.

Eli Lilly vs Novo Nordisk

The trial’s publication coincides with another headline-making announcement: Eli Lilly reported that orforglipron outperformed rival Novo Nordisk’s oral drug, oral semaglutide (Rybelsus), in Novo Nordisk's own head-to-head study on Type 2 diabetes patients.

Blood sugar control at 52 weeks:

• Orforglipron (36 mg): 2.2% reduction in HbA1c
• Oral semaglutide (14 mg): 1.4% reduction

Weight loss:

• Orforglipron: average 9.2% (19.7 pounds)
• Oral semaglutide: average 5.3% (11 pounds)

When including all patients regardless of discontinuation, weight loss with orforglipron was 8.2% compared to 5.3% with oral semaglutide.

Eli Lilly’s chief scientific officer Dan Skovronsky said the pill could serve as “the main medicine” for patients needing both diabetes and obesity management. Independent experts have also praised the results. Dr. Michael Weintraub of NYU Langone noted the pill’s blood sugar control is “impressive not only compared to other oral medications but also injectables.”

Caveats and Next Steps

Despite the strong results, analysts caution against declaring a clear winner in the oral weight-loss pill race. Novo Nordisk is awaiting FDA approval for a 25 mg version of oral semaglutide for obesity and has tested a 50 mg dose. Higher doses could narrow or close the gap between the two companies.

Dr. Jaime Almandoz of UT Southwestern Medical Center said:

“It’s a little too early to say that one is the leader in this class. But having head-to-head data helps doctors make better decisions for patients.”

Eli Lilly says it plans to apply for regulatory approval of orforglipron for diabetes in 2026, with a global launch expected as early as next year. Detailed results from its head-to-head study will be presented at an upcoming medical meeting.

Your eyes could be giving you clues that your kidneys aren’t working the way they should. While most people associate kidney trouble with tiredness, swelling, or changes in urination, the effects can also show up in your vision. To understand this better, we spoke with Dr Manoj K. Singhal, Principal Director of Nephrology and Kidney Transplantation at Max Super Speciality Hospital, Vaishali.

5 Eye Symptoms Linked to Kidney Issues

The kidneys filter toxins and help maintain balance in the body. But when they start to weaken, some of the earliest signs may appear in unexpected places, like your eyes. Some of these symptoms, as per Dr Manoj are:

1. Persistent Puffiness

It’s normal to wake up with puffy eyes, but if the swelling doesn’t fade even after rest, it could point to protein leaking into your urine, a condition called proteinuria, which often signals kidney damage.

2. Blurred or Double Vision

Sudden blurriness may be tied to high blood pressure or diabetes—two major causes of kidney problems. These conditions damage small blood vessels in the eyes and can even lead to sudden vision loss.

3. Dry, Itchy Eyes

Many people with chronic kidney disease, especially those on dialysis, experience dryness or irritation in the eyes. This happens when mineral balance in the body is disrupted, leaving the eyes feeling gritty or uncomfortable.

ALSO READ: What Is Babesia That Could Block Your Lyme Disease Recovery?

4. Red or Bloodshot Eyes

Frequent redness can be a warning sign of uncontrolled blood pressure or diabetes. In some rare cases, kidney-related conditions like lupus nephritis can also cause eye problems.

5. Difficulty Seeing Colours

Kidney disease can sometimes affect the optic nerve or retina, making it harder to distinguish certain colours, especially shades of blue and yellow.

When To Seek Help?

Not every eye problem points to kidney disease, but if these symptoms persist or worsen, it’s worth getting both your vision and kidney health checked. Routine eye exams can sometimes reveal early warning signs before bigger problems develop.

If you notice changes in your eyesight alongside other symptoms like fatigue, swelling, or urinary changes, don’t ignore them. Catching kidney issues early can make all the difference for both your eye health and your overall well-being.

ALSO READ: COVID-19 Is No Longer One Of The Top 10 Causes Of Death In US, What Diseases Remain In the Updated List

How To Protect Your Kidneys and Eyes

While some kidney issues are unavoidable, there are steps you can take to reduce your risk and protect both your kidney and eye health, as suggested by Dr Manoj:

• Maintain a Healthy Blood Pressure and Blood Sugar: High blood pressure and diabetes are major risk factors for kidney disease. Regular monitoring and a balanced diet can help keep these in check.
• Stay Hydrated: Drinking enough water supports kidney function and helps flush out toxins.
• Eat a Balanced Diet: Focus on fruits, vegetables, whole grains, and lean proteins while limiting salt, processed foods, and excess sugar.
• Exercise Regularly: Physical activity improves circulation and helps maintain healthy blood pressure, supporting both kidney and eye health.
• Avoid Smoking and Excess Alcohol: Both can damage blood vessels, increasing the risk of kidney and eye problems.
• Schedule Regular Checkups: Routine blood tests, urine tests, and eye exams can help catch early signs of kidney issues before they worsen.

Taking care of your overall health is the best way to safeguard your kidneys. and your eyes from long-term damage.

Suicides are one of the leading causes of death around the world. While it is easy to say that the person who chose to take their lives did it of their own violation, Harvard psychologist Dr. Matthew Nock, explains the other side. “90% of people who try and kill themselves say, I didn't want to die per se. I wanted to escape from seemingly intolerable.” Speaking on the On Purpose podcast with Jay Shetty, Dr. Nock pointed out that the link between work pressure and suicidal thoughts varies by race and ethnicity.

The concerning rise in suicide cases tied to work pressure has fueled a social media conversation about toxic work culture. What was once considered a normal part of the professional grind is now being openly challenged, as people share personal stories of the anxiety, depression, and isolation caused by unhealthy work environments.

What Professions Are At High Risk Of Suicide?

According to Dr. Matthew Nock, certain careers are linked to a higher risk of suicide.

Police Officers

He noted that physicians and police officers are among those at high risk. He mentioned a spike in suicides among New York City police officers, who are predominantly white men, and shared that female police officers, in particular, face a higher risk, even when accounting for factors like age, race, and ethnicity.

According to a 2025 study published in the Police Practice and Research, on average, 21.4 out of every 100,000 officers died by suicide each year.

The study showed that the suicide rate was much higher for male officers (22.7 per 100,000) than for female officers (12.7 per 100,000).

Physicians

Dr. Nock explained that access to means is a significant factor in these high-risk professions, which helps explain why physicians, police officers, and military members have a much higher risk of suicide compared to others.

Another study published in 2024 The BMJ, showed that the number of suicides among doctors has been going down, female doctors are still at a much higher risk than other people.

When looking at all the data, male doctors were found to have a 5% higher risk of suicide compared to the general population.

In a more recent analysis of the last few years, the overall suicide rate for doctors has decreased, which is good news. But even with this improvement, female doctors still have a 24% higher risk than the general public.

Why We Need To Talk More About Suicide

Dr. Nock stresses the importance of openly discussing suicide, particularly in schools. He compared it to fire drills or earthquake preparedness, saying that since 15% of people will experience suicidal thoughts, it's crucial to equip everyone with a safety plan..Dr. Matthew Nock said, "We know that asking about suicide, talking about suicide, does not make people suicidal."

He noted that the people who act on suicidal thoughts often show different signs than those who just have the thoughts. While depression is a strong predictor of having suicidal thoughts, other factors like anxiety, aggressiveness, poor behavioral control, and drug or alcohol use are more closely linked to a person actually attempting suicide.

He believes that a small educational module on suicide in health class could help save lives by teaching people what to do if they or someone they know is struggling.